GO:0071360

From wiki-pain
Jump to: navigation, search
Name cellular response to exogenous dsRNA
Categary Process
Go Slim No
Go Link GO:0071360
Unique Molecular Interactions 58
Total Molecular Interactions 71
Total Single Events 377
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular response to exogenous dsRNA. They are ordered first by their pain relevance and then by number of times they were reported for cellular response to exogenous dsRNA. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT165183 Ifnb1 Positive_regulation of P2rx4 1 0.04 1.73 1.73
2 INT142661 Binding of IFIT1 and NPY2R 1 0.00 2.49 1.08
3 INT116771 Binding of MAVS and MRGPRX1 1 0.00 0.51 0.89
4 INT150733 Negative_regulation of Tlr3 Negative_regulation of Positive_regulation of Il1b 1 0.48 1.34 0.83
5 INT116020 Positive_regulation of Binding of Il4 and Mavs 1 0.02 0.08 0.7
6 INT116021 Binding of Il4 and Mavs 1 0.02 0.08 0.7
7 INT116019 Negative_regulation of Binding of Il4 and Mavs 1 0.02 0.08 0.7
8 INT183695 Binding of Tlr3 and Ducm1 1 0.04 2.75 0.56
9 INT158599 Tlr3 Positive_regulation of Binding of Fas 1 0.55 0.86 0.48
10 INT296795 Binding of Tlr9 and Tlr3 2 0.22 1.29 0.45
11 INT140574 Ifnb1 Positive_regulation of Il6 1 0.05 0.9 0.39
12 INT140571 Ifng Positive_regulation of Ifnb1 1 0.01 0.82 0.36
13 INT140575 Il6 Positive_regulation of Ifnb1 1 0.02 0.82 0.36
14 INT140572 Ifng Positive_regulation of Gene_expression of Ifnb1 1 0.01 0.82 0.36
15 INT140573 Positive_regulation of Ifng Positive_regulation of Ifnb1 1 0.01 0.83 0.36
16 INT174699 Binding of Tlr2 and Tlr3 3 0.14 0.66 0.35
17 INT330383 Binding of TLR2 and TLR3 1 0.07 2.77 0.31
18 INT330378 Positive_regulation of Binding of TLR2 and TLR3 1 0.10 2.78 0.31
19 INT137167 Binding of IFNG and TLR3 1 0.24 0.32 0.27
20 INT324873 Binding of Jun and Tlr3 1 0.01 1.54 0.22
21 INT350006 Tlr4 Regulation of Positive_regulation of Tlr3 1 0.41 0.17 0.21
22 INT350005 Tlr3 Positive_regulation of Il17rb 1 0.09 0.32 0.21
23 INT330371 Binding of TLR3 and Ifx 1 0.17 1.12 0.2
24 INT339505 Tlr3 Positive_regulation of Eif2ak2 1 0.14 0.09 0.19
25 INT246414 TLR4 Regulation of Gene_expression of TLR3 1 0.35 1.16 0.17
26 INT350711 Ifnb1 Negative_regulation of Gene_expression of DICER1 1 0.03 0.15 0.14
27 INT346500 TLR3 Positive_regulation of Nfkb1 1 0.01 0.49 0.13
28 INT290314 MAVS Positive_regulation of DDX58 1 0.06 0.63 0.13
29 INT183702 Binding of Tlr3 and Pilra 1 0.02 0.64 0.11
30 INT183694 Ducm1 Positive_regulation of Gene_expression of Tlr3 1 0.03 0.23 0.11
31 INT324870 Binding of Ticam1 and Tlr3 1 0.03 0.76 0.11
32 INT254223 Tlr3 Positive_regulation of Myd88 1 0.16 0.23 0.08
33 INT346452 TLR3 Positive_regulation of TBK1 1 0.03 0.45 0.06
34 INT346456 TLR3 Positive_regulation of IKBKE 1 0.02 0.45 0.06
35 INT329045 Binding of Unc93b1 and Tlr3 1 0.03 0.7 0.05
36 INT246413 TLR4 Regulation of TLR3 1 0.28 0.81 0.05
37 INT350802 Binding of MYD88 and TLR3 1 0.01 0 0.04
38 INT350800 Binding of TLR3 and TICAM1 1 0.01 0 0.04
39 INT337167 Binding of TLR3 and Positive_regulation of CD83 1 0.13 0.31 0.03
40 INT337174 Binding of TLR3 and Positive_regulation of CCR7 1 0.15 0.31 0.03
41 INT337183 Binding of TLR3 and Positive_regulation of CD274 1 0.16 0.31 0.03
42 INT337179 Binding of TLR3 and Positive_regulation of CD86 1 0.10 0.31 0.03
43 INT204997 Ppp1r15b Regulation of Mavs 1 0.00 0.87 0
44 INT284563 Tlr3 Positive_regulation of Mat1a 1 0.22 2.43 0
45 INT348015 Binding of Tlr4 and Tlr3 1 0.19 0 0
46 INT285422 Regulation of Binding of TLR1 and TLR3 1 0.30 0 0
47 INT246412 Binding of TLR3 and TLR4 1 0.38 0 0
48 INT285426 Binding of TLR1 and TLR3 1 0.25 0 0
49 INT20010 Binding of Ifnb1 and Ifng 1 0.01 0 0
50 INT246411 Positive_regulation of Binding of TLR3 and TLR4 1 0.51 0 0
51 INT217314 IFNA1 Positive_regulation of MAVS 1 0.01 1.47 0
52 INT284566 Tlr3 Positive_regulation of Mthfd1 1 0.17 2.43 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular response to exogenous dsRNA. They are ordered first by their pain relevance and then by number of times they were reported in cellular response to exogenous dsRNA. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT183681 Positive_regulation of Tlr3 20 0.62 16.25 4.54
2 INT137178 Gene_expression of TLR3 46 0.72 24.97 4.33
3 INT158595 Gene_expression of Tlr3 25 0.69 12.09 4.07
4 INT158596 Binding of Tlr3 24 0.47 11.66 3.69
5 INT64982 Positive_regulation of Ifnb1 10 0.48 6.16 2.35
6 INT109010 Negative_regulation of Ifnb1 1 0.12 2.47 1.56
7 INT23986 Positive_regulation of Ifnb1 4 0.42 0.62 1.39
8 INT14335 Gene_expression of Ifnb1 5 0.40 2.7 1.38
9 INT186810 Positive_regulation of TLR3 13 0.65 6.37 1.37
10 INT150730 Regulation of Tlr3 2 0.45 6.51 1.37
11 INT150729 Negative_regulation of Tlr3 3 0.43 3.26 1.14
12 INT186807 Positive_regulation of Gene_expression of TLR3 8 0.53 7.19 1.08
13 INT288489 Transcription of Tlr3 1 0.51 3.85 1.05
14 INT288483 Gene_expression of Tlr3 8 0.72 4.51 0.97
15 INT126566 Binding of Ifnb1 3 0.31 2.43 0.85
16 INT186804 Binding of TLR3 14 0.45 8.41 0.79
17 INT136147 Regulation of Ifnb1 2 0.44 1.75 0.72
18 INT255974 Transcription of Tlr3 10 0.49 6.11 0.7
19 INT186798 Regulation of TLR3 5 0.42 3.13 0.69
20 INT116007 Negative_regulation of Mavs 1 0.03 0.08 0.69
21 INT142662 Binding of IFIT1 2 0.02 2.26 0.66
22 INT29259 Gene_expression of Ifnb1 4 0.65 1.32 0.62
23 INT204525 Negative_regulation of Gene_expression of TLR3 2 0.54 1.8 0.61
24 INT288485 Regulation of Transcription of Tlr3 1 0.20 0.85 0.61
25 INT246423 Negative_regulation of TLR3 1 0.40 2.2 0.6
26 INT254177 Positive_regulation of Positive_regulation of Tlr3 3 0.41 2.06 0.58
27 INT183685 Positive_regulation of Gene_expression of Tlr3 4 0.61 1.5 0.53
28 INT29258 Positive_regulation of Gene_expression of Ifnb1 2 0.42 2.16 0.51
29 INT84573 Regulation of Mavs 1 0.01 1.37 0.49
30 INT123720 Negative_regulation of Positive_regulation of Ifnb1 1 0.34 0.26 0.45
31 INT76021 Negative_regulation of Positive_regulation of Ifnb1 1 0.40 0.19 0.44
32 INT166728 Regulation of MAVS 1 0.32 0.15 0.44
33 INT237905 Positive_regulation of Binding of Tlr3 1 0.30 0.79 0.42
34 INT183680 Localization of Tlr3 6 0.71 1.69 0.39
35 INT140576 Positive_regulation of Regulation of Ifnb1 1 0.30 0.9 0.39
36 INT140577 Positive_regulation of Gene_expression of Ifnb1 1 0.30 0.81 0.36
37 INT246419 Positive_regulation of Negative_regulation of TLR3 1 0.43 0.67 0.34
38 INT346492 Protein_catabolism of MAVS 1 0.06 1.74 0.31
39 INT51504 Negative_regulation of Gene_expression of Ifnb1 1 0.01 0.49 0.25
40 INT303626 Positive_regulation of IFIT1 1 0.02 1.59 0.23
41 INT118614 Regulation of IFIT1 1 0.00 0.38 0.21
42 INT186803 Transcription of TLR3 6 0.67 1.54 0.2
43 INT254194 Regulation of Positive_regulation of Tlr3 2 0.52 0.79 0.19
44 INT288491 Positive_regulation of Transcription of Tlr3 1 0.37 1.85 0.19
45 INT346978 Negative_regulation of IFIT1 1 0.13 1.83 0.17
46 INT336418 Negative_regulation of Binding of Tlr3 1 0.36 0.59 0.16
47 INT204974 Positive_regulation of Mavs 1 0.02 3.77 0.16
48 INT204989 Gene_expression of Mavs 3 0.02 0.86 0.15
49 INT346493 Binding of MAVS 1 0.03 0.54 0.15
50 INT287133 Negative_regulation of Binding of Ifnb1 1 0.11 0.31 0.15
51 INT279781 Gene_expression of MAVS 4 0.15 3.51 0.12
52 INT186797 Localization of TLR3 2 0.70 2.69 0.12
53 INT186809 Positive_regulation of Transcription of TLR3 2 0.65 0.5 0.11
54 INT246420 Regulation of Gene_expression of TLR3 1 0.57 0.79 0.11
55 INT255970 Regulation of Transcription of Tlr3 1 0.24 0.89 0.09
56 INT329066 Positive_regulation of Gene_expression of Tlr3 1 0.43 1.12 0.08
57 INT217383 Regulation of Regulation of Mavs 1 0.01 0.79 0.08
58 INT228376 Binding of Tlr3 2 0.45 2.2 0.07
59 INT285436 Negative_regulation of Transcription of TLR3 1 0.24 0.32 0.07
60 INT217374 Positive_regulation of Regulation of Mavs 1 0.01 0.37 0.05
61 INT329051 Positive_regulation of Tlr3 1 0.65 0.33 0.04
62 INT320335 Positive_regulation of Transcription of Tlr3 1 0.43 0.13 0.03
63 INT204980 Regulation of Gene_expression of Mavs 1 0.01 0.3 0.03
64 INT186806 Positive_regulation of Binding of TLR3 1 0.39 0.07 0.03
65 INT265417 Positive_regulation of Positive_regulation of TLR3 2 0.16 1.1 0
66 INT323996 Localization of IFIT1 1 0.56 0.37 0
67 INT260426 Regulation of Gene_expression of Tlr3 1 0.23 0.77 0
68 INT303646 Gene_expression of IFIT1 1 0.03 0.97 0
69 INT303642 Positive_regulation of Positive_regulation of IFIT1 1 0.02 0.55 0
70 INT322621 Regulation of Positive_regulation of TLR3 1 0.04 0.41 0
71 INT273927 Transcription of Mavs 1 0.00 0 0
72 INT303645 Positive_regulation of Gene_expression of IFIT1 1 0.02 0.97 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox