GO:0071361

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Name cellular response to ethanol
Categary Process
Go Slim No
Go Link GO:0071361
Unique Molecular Interactions 75
Total Molecular Interactions 112
Total Single Events 1184
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular response to ethanol. They are ordered first by their pain relevance and then by number of times they were reported for cellular response to ethanol. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT107801 Ugt1a5 Positive_regulation of Localization of Prl 3 0.76 1 3.9
2 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
3 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
4 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
5 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46
6 INT147659 Prkce Positive_regulation of TRPV1 1 0.04 1.42 2.43
7 INT135582 Prok2 Positive_regulation of Localization of Prkce 1 0.06 1.02 1.87
8 INT150835 Gper Positive_regulation of Localization of Prkce 1 0.15 0.62 1.18
9 INT147660 Positive_regulation of Prkce Positive_regulation of TRPV1 1 0.04 0.69 1.12
10 INT96905 Plxna3 Regulation of Regulation of Prkce 1 0.18 0.71 1.07
11 INT109842 Prkce Positive_regulation of Localization of Trpv1 1 0.13 1.31 0.91
12 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
13 INT87490 CALCA Positive_regulation of Gene_expression of CCL5 1 0.30 0.14 0.81
14 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
15 INT104749 Ugt1a1 Regulation of Positive_regulation of G2e3 1 0.00 0.07 0.77
16 INT149493 PNOC Negative_regulation of CCL5 1 0.14 0.16 0.77
17 INT104748 Ugt1a1 Regulation of Positive_regulation of LOC100359830 1 0.01 0.07 0.77
18 INT258644 Binding of CCL2 and CCL5 1 0.36 1.6 0.74
19 INT258643 Positive_regulation of Binding of CCL2 and CCL5 1 0.49 1.61 0.74
20 INT67809 Ugt2b1 Negative_regulation of Ugt2b7 1 0.47 0 0.7
21 INT148454 Gene_expression of Inhbe Positive_regulation of Prkce 1 0.08 0.67 0.69
22 INT154766 Nox1 Positive_regulation of Localization of Prkce 1 0.47 0.45 0.66
23 INT112513 Binding of Prkaca and Prkce 1 0.04 0.4 0.64
24 INT112516 Binding of Prkce and Trib3 1 0.01 0.4 0.64
25 INT316831 CCL5 Positive_regulation of Gene_expression of MMP2 1 0.02 0.51 0.59
26 INT60481 Binding of Ugt1a1 and UGT1A6 1 0.23 0 0.55
27 INT144129 Prkce Positive_regulation of Phosphorylation of Gja1 1 0.42 0.48 0.55
28 INT144128 Binding of Gja1 and Prkce 1 0.40 0.5 0.52
29 INT140356 Prkca Regulation of Phosphorylation of Prkce 1 0.18 0.44 0.52
30 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
31 INT107803 Ugt1a5 Positive_regulation of Prl 2 0.44 0.48 0.48
32 INT171278 TNFSF12 Positive_regulation of CCL5 1 0.02 0.93 0.48
33 INT316830 TNF Regulation of CCL5 1 0.02 1.02 0.39
34 INT107802 Ugt1a5 Regulation of Localization of Prl 1 0.29 0.19 0.32
35 INT103279 PGR Negative_regulation of Gene_expression of CCL5 1 0.32 0.31 0.27
36 INT266802 Dlst Positive_regulation of CCL5 1 0.00 0.95 0.25
37 INT252815 Binding of CCL5 and TNF 1 0.02 0.75 0.25
38 INT56632 Ugt2b17 Regulation of Mgst1 1 0.04 0.06 0.24
39 INT80286 IFNG Positive_regulation of Gene_expression of CCL5 1 0.24 0.37 0.23
40 INT80287 IL4 Positive_regulation of Gene_expression of CCL5 1 0.21 0.37 0.23
41 INT196635 CFTR Positive_regulation of Gene_expression of CCL5 1 0.07 0.44 0.21
42 INT295713 PTGER2 Positive_regulation of Regulation of CCL5 1 0.01 0.82 0.21
43 INT170995 Binding of IFNA1 and Positive_regulation of Localization of CCL5 1 0.03 0.34 0.19
44 INT303937 Positive_regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
45 INT303940 Regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
46 INT226344 Gene_expression of IL9 Positive_regulation of CCL5 1 0.07 1.03 0.18
47 INT303938 Binding of GLI2 and CCL5 1 0.01 0 0.18
48 INT319173 TXN Positive_regulation of Gene_expression of SOD2 1 0.23 0.1 0.18
49 INT329795 IL6 Positive_regulation of Transcription of CCL5 1 0.02 0.59 0.17
50 INT50607 Ugt1a5 Regulation of Cpa5 1 0.02 0 0.14
51 INT50609 Ugt1a5 Regulation of Ins1 1 0.07 0 0.14
52 INT134614 Prkce Regulation of Trpv1 1 0.30 0.15 0.13
53 INT110107 Acot1 Positive_regulation of Localization of Prkce 1 0.11 0 0.12
54 INT171295 CXCL10 Positive_regulation of CCL5 1 0.04 0.06 0.12
55 INT171297 TNF Positive_regulation of Localization of CCL5 1 0.17 0.66 0.07
56 INT302131 Negative_regulation of SOD2 Regulation of BAK1 1 0.09 1.22 0.07
57 INT302128 SOD2 Regulation of BAK1 1 0.09 1.22 0.07
58 INT145626 Binding of PKLR and UGT1A1 1 0.02 0 0.06
59 INT122216 IL1B Positive_regulation of CCL5 3 0.67 0.53 0.04
60 INT171279 IL6 Positive_regulation of CCL5 1 0.04 0.38 0.04
61 INT171301 TNF Positive_regulation of CCL5 1 0.16 0.38 0.04
62 INT122217 IL1B Positive_regulation of Gene_expression of CCL5 2 0.52 0.08 0
63 INT127690 TNF Positive_regulation of Regulation of CCL5 1 0.33 0.17 0
64 INT171282 TNFSF12 Positive_regulation of Gene_expression of CCL5 1 0.01 0 0
65 INT169448 Binding of Prkce and Trpv4 1 0.04 0.08 0
66 INT156700 Binding of Crp and UGT1A1 1 0.40 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular response to ethanol. They are ordered first by their pain relevance and then by number of times they were reported in cellular response to ethanol. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09
2 INT78901 Localization of CCL5 67 0.78 40.79 20.59
3 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62
4 INT64563 Gene_expression of UGT1A1 27 0.75 3.31 13.43
5 INT88650 Negative_regulation of Prkce 13 0.57 11.93 11.16
6 INT4240 Positive_regulation of CCL5 32 0.58 20.55 10.65
7 INT91948 Positive_regulation of Prkce 16 0.64 11.36 10.32
8 INT78895 Regulation of CCL5 30 0.46 20.45 10.18
9 INT87495 Positive_regulation of Gene_expression of CCL5 26 0.69 13.85 9.46
10 INT72148 Positive_regulation of Prkce 17 0.68 5.06 9.44
11 INT89589 Negative_regulation of Ccl5 9 0.40 4.62 7.39
12 INT103824 Positive_regulation of SOD2 26 0.70 17.42 7.17
13 INT58625 Gene_expression of Ugt2b1 19 0.77 1.95 7.05
14 INT39282 Negative_regulation of SOD2 27 0.59 16.89 7.03
15 INT110104 Localization of Prkce 17 0.79 3.75 6.92
16 INT92470 Negative_regulation of Gene_expression of CCL5 15 0.50 5.46 5.86
17 INT13685 Positive_regulation of Ugt2b17 13 0.69 3.3 5.75
18 INT60475 Gene_expression of Ugt1a1 17 0.77 4.26 5.62
19 INT101497 Phosphorylation of Prkce 9 0.81 2.55 5.59
20 INT91946 Regulation of Prkce 6 0.44 4.13 5.46
21 INT109838 Phosphorylation of Prkce 6 0.67 5.26 4.95
22 INT82887 Positive_regulation of Ccl5 10 0.40 3.4 4.91
23 INT89590 Negative_regulation of Gene_expression of Ccl5 8 0.36 3.97 4.67
24 INT60758 Gene_expression of Prkce 8 0.20 4.12 4.59
25 INT20052 Negative_regulation of UGT1A1 12 0.58 4.51 4.29
26 INT4239 Negative_regulation of CCL5 15 0.40 10.92 4.26
27 INT20096 Binding of Ugt2b17 1 0.22 0 4.15
28 INT103281 Transcription of CCL5 10 0.67 5.95 3.7
29 INT39199 Positive_regulation of Ugt1a1 9 0.45 1.78 3.69
30 INT89592 Localization of Ccl5 10 0.61 7.65 3.62
31 INT99453 Gene_expression of SOD2 25 0.77 13.28 3.6
32 INT109840 Localization of Prkce 5 0.74 3.01 3.45
33 INT124123 Positive_regulation of Localization of CCL5 12 0.67 7 3.37
34 INT65120 Regulation of Ugt1a1 3 0.45 1.07 3.29
35 INT82879 Regulation of Ccl5 9 0.30 6.19 3.17
36 INT110100 Negative_regulation of Prkce 5 0.57 0.68 3.16
37 INT78898 Regulation of Gene_expression of CCL5 9 0.42 5.7 3.11
38 INT115617 Binding of Ccl5 5 0.33 0.58 3.11
39 INT194661 Binding of CCL5 9 0.46 6.07 2.73
40 INT128184 Positive_regulation of Positive_regulation of Prkce 4 0.41 1.3 2.64
41 INT58624 Positive_regulation of Ugt2b1 5 0.69 0.22 2.5
42 INT88225 Transcription of Ugt1a1 5 0.61 1.51 2.4
43 INT128185 Gene_expression of Prkce 4 0.69 1.39 2.23
44 INT109334 Regulation of SOD2 13 0.60 7.48 2.14
45 INT99410 Positive_regulation of UGT1A1 10 0.45 2.2 2.07
46 INT136941 Positive_regulation of Localization of Prkce 3 0.43 1.42 2.06
47 INT115616 Positive_regulation of Binding of Ccl5 3 0.25 0.59 2.04
48 INT124052 Binding of Prkce 2 0.06 2.52 2.03
49 INT63672 Negative_regulation of Ugt2b1 7 0.57 1.07 1.9
50 INT103061 Positive_regulation of Gene_expression of Ccl5 4 0.35 1.67 1.9
51 INT38195 Localization of Ugt1a5 2 0.55 0.3 1.87
52 INT148944 Transcription of UGT1A1 3 0.59 0.07 1.84
53 INT194660 Positive_regulation of Binding of CCL5 1 0.42 2.74 1.72
54 INT78896 Negative_regulation of Localization of CCL5 8 0.57 2.43 1.59
55 INT2316 Positive_regulation of Ugt1a5 5 0.67 0.84 1.52
56 INT178615 Binding of SOD2 12 0.48 6.93 1.51
57 INT171015 Positive_regulation of Positive_regulation of CCL5 3 0.42 3.63 1.51
58 INT44288 Binding of Ugt1a1 7 0.45 0.54 1.48
59 INT88224 Positive_regulation of Transcription of Ugt1a1 1 0.29 0.54 1.48
60 INT78889 Binding of UGT1A1 10 0.47 3.41 1.47
61 INT58626 Positive_regulation of Gene_expression of Ugt2b1 3 0.50 0.07 1.45
62 INT115895 Phosphorylation of Ccl5 1 0.55 0 1.31
63 INT91947 Negative_regulation of Negative_regulation of Prkce 1 0.42 0.69 1.3
64 INT67810 Regulation of Ugt2b1 1 0.45 0.1 1.26
65 INT110099 Positive_regulation of Localization of Prkce 4 0.68 1.3 1.25
66 INT91949 Regulation of Positive_regulation of Prkce 1 0.44 0.72 1.24
67 INT110106 Regulation of Prkce 4 0.44 0.4 1.2
68 INT149554 Transcription of Ccl5 2 0.59 0.55 1.14
69 INT115893 Negative_regulation of Binding of Ccl5 1 0.37 0 1.14
70 INT110102 Negative_regulation of Localization of Prkce 3 0.49 0.17 1.13
71 INT131238 Negative_regulation of Positive_regulation of Prkce 1 0.41 0.44 1.12
72 INT20095 Negative_regulation of Ugt2b17 4 0.42 0.76 1.03
73 INT208244 Regulation of Gene_expression of Ccl5 1 0.26 1.92 1.01
74 INT135111 Regulation of Gene_expression of Prkce 1 0.51 0.15 0.96
75 INT135115 Regulation of Localization of Prkce 1 0.38 0.15 0.96
76 INT69779 Transcription of Ugt2b1 9 0.69 0.94 0.93
77 INT39198 Negative_regulation of Ugt1a1 7 0.52 1.35 0.92
78 INT103285 Regulation of Localization of CCL5 3 0.44 1.11 0.89
79 INT35376 Gene_expression of Ugt2b17 6 0.64 0.61 0.88
80 INT149555 Negative_regulation of Positive_regulation of Ccl5 1 0.15 0 0.88
81 INT136944 Positive_regulation of Positive_regulation of Prkce 2 0.46 0.8 0.85
82 INT57168 Binding of Ugt2b1 2 0.48 0 0.81
83 INT103823 Positive_regulation of Gene_expression of SOD2 10 0.68 4.69 0.79
84 INT9974 Regulation of Ugt2b17 3 0.61 0.95 0.79
85 INT109839 Positive_regulation of Phosphorylation of Prkce 1 0.18 1.27 0.71
86 INT154761 Positive_regulation of Gene_expression of Prkce 1 0.44 0.5 0.7
87 INT154762 Negative_regulation of Phosphorylation of Prkce 1 0.38 0.48 0.69
88 INT2317 Gene_expression of Ugt1a5 2 0.58 0.35 0.68
89 INT112173 Regulation of Transcription of SOD2 3 0.60 2.25 0.67
90 INT108857 Transcription of SOD2 5 0.70 3.51 0.66
91 INT162521 Regulation of Gene_expression of Ugt2b1 1 0.54 0.19 0.66
92 INT115897 Positive_regulation of Phosphorylation of Ccl5 1 0.41 0 0.66
93 INT159283 Negative_regulation of Transcription of Ugt1a1 1 0.38 0.15 0.62
94 INT159281 Negative_regulation of Transcription of Ugt2b1 1 0.39 0.15 0.62
95 INT159280 Negative_regulation of Transcription of Ugt2b17 1 0.41 0.15 0.62
96 INT159279 Transcription of Ugt2b17 1 0.67 0.15 0.61
97 INT108856 Regulation of Gene_expression of SOD2 3 0.44 0.79 0.58
98 INT152068 Regulation of Gene_expression of Prkce 1 0.05 0.74 0.56
99 INT136942 Negative_regulation of Positive_regulation of Prkce 1 0.39 0.66 0.48
100 INT59208 Positive_regulation of Gene_expression of Ugt1a5 1 0.25 0.09 0.46
101 INT133783 Positive_regulation of Gene_expression of Ugt1a1 5 0.46 0.94 0.44
102 INT194658 Positive_regulation of Transcription of CCL5 1 0.45 0.68 0.44
103 INT267606 Protein_catabolism of CCL5 2 0.48 1.39 0.43
104 INT322698 Protein_catabolism of Ccl5 1 0.49 0.33 0.38
105 INT159542 Localization of SOD2 5 0.80 1.91 0.36
106 INT128693 Localization of Ugt2b17 1 0.71 0 0.36
107 INT67103 Negative_regulation of Ugt1a5 1 0.34 0 0.34
108 INT139941 Localization of Ugt1a1 2 0.70 0.21 0.33
109 INT195733 Phosphorylation of CCL5 2 0.10 1.04 0.33
110 INT103283 Negative_regulation of Transcription of CCL5 1 0.50 0.28 0.27
111 INT319179 Positive_regulation of Positive_regulation of SOD2 1 0.68 0.51 0.27
112 INT147521 Regulation of Gene_expression of Ugt1a1 2 0.23 0.39 0.26
113 INT322710 Positive_regulation of Transcription of Ccl5 1 0.43 0.56 0.26
114 INT159284 Localization of Ugt2b1 1 0.73 0.07 0.25
115 INT69778 Positive_regulation of Transcription of Ugt2b1 3 0.64 0.14 0.24
116 INT109333 Negative_regulation of Gene_expression of SOD2 2 0.42 0.71 0.24
117 INT19022 Regulation of Ugt1a5 2 0.14 0.55 0.24
118 INT140351 Binding of Prkce 2 0.28 0.32 0.22
119 INT278672 Positive_regulation of Transcription of UGT1A1 1 0.27 0.07 0.22
120 INT282377 Regulation of Positive_regulation of CCL5 1 0.05 1.12 0.22
121 INT169685 Regulation of Positive_regulation of Prkce 1 0.61 0.36 0.22
122 INT133784 Protein_catabolism of Ugt1a1 1 0.26 0.49 0.19
123 INT319182 Positive_regulation of Negative_regulation of SOD2 1 0.46 0.95 0.17
124 INT232580 Protein_catabolism of SOD2 2 0.97 1.22 0.16
125 INT89593 Negative_regulation of Localization of Ccl5 1 0.03 0.46 0.15
126 INT105897 Regulation of UGT1A1 3 0.60 1.6 0.13
127 INT195730 Negative_regulation of Binding of CCL5 1 0.05 0.51 0.13
128 INT319178 Regulation of Negative_regulation of SOD2 1 0.27 0.53 0.11
129 INT333947 Regulation of Regulation of SOD2 1 0.42 0.14 0.07
130 INT278678 Positive_regulation of Gene_expression of UGT1A1 1 0.37 0.09 0.06
131 INT104744 Negative_regulation of Gene_expression of Ugt1a1 2 0.53 0.85 0
132 INT333949 Positive_regulation of Localization of SOD2 1 0.46 0.32 0
133 INT108855 Positive_regulation of Transcription of SOD2 1 0.47 0.07 0
134 INT349463 Negative_regulation of Gene_expression of UGT1A1 1 0.22 1.05 0
135 INT104747 Positive_regulation of Binding of Ugt1a1 1 0.45 0 0
136 INT168332 Regulation of Transcription of Ugt2b1 1 0.44 0.19 0
137 INT330964 Negative_regulation of Transcription of SOD2 1 0.15 1.22 0
138 INT169684 Positive_regulation of Phosphorylation of Prkce 1 0.49 0.05 0
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