GO:0071371

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Name cellular response to gonadotropin stimulus
Categary Process
Go Slim No
Go Link GO:0071371
Unique Molecular Interactions 86
Total Molecular Interactions 98
Total Single Events 1313
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular response to gonadotropin stimulus. They are ordered first by their pain relevance and then by number of times they were reported for cellular response to gonadotropin stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT89873 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.23 0 1.29
2 INT89876 Pdyn Positive_regulation of Gata4 1 0.23 0 1.28
3 INT229913 Positive_regulation of Ntsr1 Positive_regulation of Gene_expression of Egr1 1 0.12 1.33 1.11
4 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02
5 INT61860 Akr1d1 Regulation of Egr1 1 0.01 0 0.96
6 INT61861 Akr1d1 Regulation of Positive_regulation of Egr1 1 0.01 0 0.96
7 INT61859 Akr1d1 Positive_regulation of Egr1 1 0.01 0 0.92
8 INT61862 Slc3a1 Positive_regulation of Egr1 1 0.05 0 0.92
9 INT101259 Gata6 Negative_regulation of Gene_expression of ALOX15 1 0.42 0.67 0.89
10 INT122350 Ngf Regulation of Hsd3b1 1 0.34 0 0.87
11 INT101258 Gene_expression of Gata6 Negative_regulation of Positive_regulation of ALOX15 1 0.42 0.65 0.87
12 INT123494 Binding of Egr1 and Ccr5 1 0.04 0.94 0.71
13 INT92025 Egr1 Positive_regulation of Jun 1 0.15 0.61 0.67
14 INT92026 Egr1 Positive_regulation of Fos 1 0.50 0.61 0.67
15 INT231027 LOC100366054 Negative_regulation of Gene_expression of Pgr 1 0.02 0 0.62
16 INT109065 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.00 0 0.58
17 INT261478 Positive_regulation of Ephb1 Regulation of Gene_expression of Egr1 1 0.10 0.23 0.55
18 INT231034 Sec22b Positive_regulation of Gene_expression of Pgr 1 0.04 0.09 0.53
19 INT197591 Esr1 Regulation of Pgr 1 0.04 0 0.38
20 INT265015 Pgr Positive_regulation of Sds 1 0.04 0.49 0.37
21 INT245328 Binding of Esr2 and Pgr 1 0.03 0.41 0.37
22 INT123495 Negative_regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
23 INT123493 Regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
24 INT90722 Nr4a1 Positive_regulation of Egr1 1 0.20 0.48 0.35
25 INT90723 Nr4a2 Positive_regulation of Egr1 1 0.22 0.49 0.35
26 INT90724 Egr3 Positive_regulation of Egr1 1 0.33 0.48 0.35
27 INT126097 Ddc Positive_regulation of Egr1 1 0.08 0 0.32
28 INT74334 Penk Regulation of Transcription of Egr1 1 0.40 0.25 0.29
29 INT74336 Crh Regulation of Transcription of Egr1 1 0.49 0.24 0.28
30 INT5935 Por Regulation of Oprm1 1 0.19 0.51 0.28
31 INT130060 PPARG Positive_regulation of Positive_regulation of Egr1 1 0.22 0.46 0.24
32 INT197590 Esr2 Positive_regulation of Negative_regulation of Pgr 1 0.16 0 0.24
33 INT259817 Ltp Positive_regulation of Egr1 1 0.03 0.28 0.2
34 INT259812 Gtf3a Regulation of Egr1 1 0.01 0.58 0.19
35 INT259814 Binding of Arc and Egr1 1 0.34 0.55 0.19
36 INT259813 Binding of Egr1 and Arc 1 0.32 0.55 0.19
37 INT149096 PITX2 Positive_regulation of Gene_expression of Egr1 1 0.01 1.23 0.19
38 INT18043 Binding of SIGMAR1 and Pgr 1 0.00 0.06 0.16
39 INT247267 Binding of Egr1 and Mecp2 1 0.12 0.18 0.13
40 INT261262 AIS Negative_regulation of Cyp19a1 1 0.01 0.2 0.08
41 INT213933 AR Negative_regulation of Cyp19a1 1 0.07 0.79 0.07
42 INT267016 Bdnf Positive_regulation of Egr1 1 0.12 0.09 0.07
43 INT168976 Binding of Wt1 and Calb2 1 0.01 1.39 0.07
44 INT339110 ERBB2 Positive_regulation of GATA6 1 0.31 0.67 0.06
45 INT197586 Esr2 Regulation of Pgr 1 0.09 0 0.06
46 INT181601 Binding of TP53 and WT1 1 0.30 0.9 0.05
47 INT181814 Gsk3b Regulation of Gata4 1 0.06 0.37 0.05
48 INT60221 Agt Regulation of Gene_expression of Egr1 1 0.42 0 0.04
49 INT276583 Binding of Wt1 and IgG 1 0.07 0 0.04
50 INT187388 Esr2 Positive_regulation of Gene_expression of Pgr 1 0.00 0.8 0.03
51 INT176564 Binding of Cyp17a1 and Cyp19a1 1 0.03 0.33 0
52 INT276586 Binding of Wt1 and Actn1 1 0.34 0.41 0
53 INT269944 Gata6 Regulation of Gene_expression of Foxj1 1 0.19 0 0
54 INT259451 Binding of DHCR7 and Cyp11a1 1 0.01 0.3 0
55 INT252910 PTTG1 Negative_regulation of Transcription of SLC5A5 1 0.02 0.36 0
56 INT197615 Esr1 Regulation of Gene_expression of Pgr 1 0.01 0.21 0
57 INT218973 Gen1 Regulation of Gene_expression of Pgr 1 0.06 0.09 0
58 INT252898 Binding of SLC5A5 and USF1 1 0.01 0.22 0
59 INT252906 Binding of SLC5A5 and PTTG1 1 0.01 0.69 0
60 INT197614 Esr1 Regulation of Pgr 1 0.01 0.07 0
61 INT259811 Narp Positive_regulation of Gene_expression of Egr1 1 0.26 0.86 0
62 INT252888 Binding of SLC5A5 and PAX8 1 0.02 0.22 0
63 INT217780 MIR181A1 Regulation of GATA6 1 0.17 0.7 0
64 INT274434 Binding of Gata4 and Zfpm2 1 0.12 0.56 0
65 INT252905 PTTG1IP Negative_regulation of Transcription of SLC5A5 1 0.01 0.35 0
66 INT197912 Dlst Positive_regulation of Gene_expression of Pgr 1 0.01 0.34 0
67 INT99772 Pgr Regulation of THBS1 1 0.00 0 0
68 INT197676 ESR1 Regulation of Gene_expression of Pgr 1 0.06 0.1 0
69 INT242178 CYP19A1 Regulation of Cyp11a1 1 0.01 0.35 0
70 INT176569 Binding of FSHR and Cyp19a1 1 0.04 0.06 0
71 INT242179 Cyp11a1 Regulation of CYP19A1 1 0.01 0.7 0
72 INT197588 Dlat Regulation of Pgr 1 0.04 0.26 0
73 INT259452 Binding of STAR and Cyp11a1 1 0.25 0.06 0
74 INT97181 Tm2d1 Positive_regulation of Transcription of Pgr 1 0.06 0 0
75 INT181599 Binding of EWSR1 and WT1 1 0.40 0.29 0
76 INT178628 Igf1 Regulation of Gene_expression of Pgr 1 0.24 0.19 0
77 INT197595 Ppt1 Regulation of Pgr 1 0.08 0.26 0
78 INT252903 PTTG1IP Regulation of Gene_expression of SLC5A5 1 0.00 0.43 0
79 INT276590 Binding of Wt1 and KTWS 1 0.02 0.3 0
80 INT252899 PTTG1 Regulation of Gene_expression of SLC5A5 1 0.01 0.43 0
81 INT277622 Esr1 Positive_regulation of Gene_expression of Cyp19a1 1 0.03 1.37 0
82 INT252890 PTTG1IP Negative_regulation of SLC5A5 1 0.01 0.34 0
83 INT269956 Gata6 Regulation of Gene_expression of Scgb1a1 1 0.17 0 0
84 INT99773 Pgr Regulation of PGR 1 0.02 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular response to gonadotropin stimulus. They are ordered first by their pain relevance and then by number of times they were reported in cellular response to gonadotropin stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13
2 INT5862 Positive_regulation of Egr1 82 0.70 30.4 33.96
3 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93
4 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19
5 INT10597 Gene_expression of Cyp19a1 27 0.78 7.48 9.11
6 INT6055 Transcription of Egr1 47 0.69 3.61 7.68
7 INT6057 Negative_regulation of Gene_expression of Egr1 17 0.57 4.17 7.17
8 INT47707 Negative_regulation of Egr1 9 0.41 0.17 7.03
9 INT5860 Regulation of Gene_expression of Egr1 20 0.62 3.02 6.38
10 INT135760 Regulation of Gene_expression of Cyp19a1 2 0.62 1.15 5.81
11 INT47704 Regulation of Egr1 17 0.60 2.43 5.18
12 INT47706 Negative_regulation of Positive_regulation of Egr1 9 0.41 6.11 5.1
13 INT51944 Positive_regulation of Transcription of Egr1 12 0.49 1.96 4.72
14 INT37652 Positive_regulation of Pgr 29 0.59 9.09 4.67
15 INT88947 Positive_regulation of Gene_expression of Pgr 22 0.64 7 4.39
16 INT123502 Binding of Egr1 11 0.35 6.7 3.77
17 INT112340 Gene_expression of Cyp11a1 11 0.77 5.19 3.7
18 INT31580 Negative_regulation of Cyp11a1 14 0.57 3.48 3.61
19 INT10824 Negative_regulation of Cyp19a1 38 0.57 25.18 3.56
20 INT116376 Transcription of Cyp19a1 2 0.40 0.74 3.04
21 INT64386 Binding of Cyp11a1 13 0.46 5.09 3.01
22 INT101246 Gene_expression of Gata6 6 0.68 3.03 2.68
23 INT38384 Regulation of Por 5 0.47 0.58 2.4
24 INT22605 Regulation of Pgr 22 0.62 7.1 2.26
25 INT178632 Regulation of Gene_expression of Pgr 11 0.35 1.56 2.26
26 INT13267 Binding of Pgr 15 0.40 3.5 2.22
27 INT80599 Regulation of Positive_regulation of Egr1 3 0.28 0.46 2.09
28 INT342803 Positive_regulation of Transcription of Cyp19a1 1 0.30 0.33 2.08
29 INT81347 Regulation of Cyp19a1 7 0.40 2.1 1.94
30 INT122346 Gene_expression of Hsd3b1 1 0.75 0 1.78
31 INT101252 Negative_regulation of Gene_expression of Gata6 1 0.51 1.3 1.74
32 INT101244 Regulation of Gata6 3 0.40 1.52 1.7
33 INT112339 Localization of Cyp11a1 2 0.71 0.94 1.68
34 INT10596 Positive_regulation of Cyp19a1 10 0.42 2.08 1.62
35 INT45711 Localization of Pgr 7 0.61 1.27 1.56
36 INT89871 Gene_expression of Gata4 11 0.69 1.05 1.53
37 INT53003 Positive_regulation of Positive_regulation of Egr1 6 0.64 2.36 1.44
38 INT10570 Positive_regulation of Cyp11a1 9 0.47 2.67 1.4
39 INT122345 Positive_regulation of Gene_expression of Hsd3b1 1 0.49 0 1.34
40 INT151 Positive_regulation of Por 5 0.62 0.42 1.31
41 INT49013 Gene_expression of Por 6 0.75 2.19 1.22
42 INT27938 Negative_regulation of Pgr 12 0.38 1.98 1.05
43 INT123503 Positive_regulation of Binding of Egr1 3 0.13 2.34 1.04
44 INT115821 Transcription of Por 1 0.33 0.51 1.02
45 INT49012 Regulation of Gene_expression of Por 1 0.44 0 1.02
46 INT109069 Transcription of Gata4 4 0.64 0.52 1.01
47 INT109070 Positive_regulation of Transcription of Gata4 1 0.03 0 1.01
48 INT123501 Negative_regulation of Binding of Egr1 2 0.12 2.04 0.99
49 INT122347 Transcription of Hsd3b1 1 0.52 0 0.99
50 INT51947 Regulation of Transcription of Egr1 2 0.59 0.15 0.96
51 INT10578 Transcription of Cyp11a1 3 0.53 0.84 0.93
52 INT178633 Negative_regulation of Gene_expression of Pgr 2 0.21 0.26 0.86
53 INT101248 Negative_regulation of Gata6 1 0.37 0.83 0.85
54 INT101251 Negative_regulation of Positive_regulation of Gata6 1 0.38 0.83 0.85
55 INT101250 Positive_regulation of Gata6 1 0.41 0.83 0.84
56 INT101245 Transcription of Gata6 2 0.47 0.85 0.82
57 INT79344 Binding of Cyp19a1 4 0.33 0.61 0.8
58 INT161339 Localization of Cyp19a1 1 0.73 1.32 0.71
59 INT101209 Gene_expression of Wt1 19 0.72 25.77 0.7
60 INT6050 Localization of Egr1 4 0.68 0.53 0.7
61 INT102686 Phosphorylation of Egr1 3 0.59 2.57 0.64
62 INT89867 Negative_regulation of Gene_expression of Gata4 3 0.38 0.17 0.61
63 INT13724 Positive_regulation of WT1 5 0.69 4.99 0.59
64 INT89868 Negative_regulation of Gata4 1 0.38 0 0.57
65 INT88694 Gene_expression of WT1 17 0.75 21.88 0.56
66 INT353896 Negative_regulation of Phosphorylation of Cyp19a1 1 0.22 0.47 0.55
67 INT353893 Phosphorylation of Cyp19a1 1 0.31 0.46 0.55
68 INT81061 Regulation of Negative_regulation of Egr1 1 0.22 0 0.53
69 INT40164 Binding of Por 2 0.37 0.5 0.51
70 INT122348 Regulation of Hsd3b1 1 0.60 0 0.46
71 INT68725 Regulation of Cyp11a1 6 0.19 2.62 0.44
72 INT121113 Protein_catabolism of Cyp11a1 2 0.65 0.37 0.44
73 INT140949 Positive_regulation of Positive_regulation of Pgr 4 0.59 1.23 0.42
74 INT84915 Negative_regulation of Gene_expression of Cyp19a1 2 0.15 1.29 0.42
75 INT265 Negative_regulation of Por 4 0.59 0.34 0.41
76 INT181122 Positive_regulation of Gene_expression of Cyp19a1 1 0.02 0.68 0.36
77 INT109058 Positive_regulation of Gene_expression of Gata4 2 0.29 0 0.33
78 INT188498 Negative_regulation of Transcription of Egr1 3 0.41 0.14 0.32
79 INT97179 Transcription of Pgr 17 0.67 4.54 0.3
80 INT117760 Regulation of Gene_expression of Cyp11a1 2 0.42 0.36 0.25
81 INT114703 Positive_regulation of Wt1 5 0.46 4.25 0.24
82 INT197602 Negative_regulation of Transcription of Pgr 1 0.25 0.09 0.24
83 INT306713 Regulation of Positive_regulation of Pgr 1 0.06 0.39 0.24
84 INT92079 Negative_regulation of Binding of Pgr 1 0.34 0 0.22
85 INT154282 Positive_regulation of Gene_expression of WT1 3 0.55 3.41 0.19
86 INT187614 Phosphorylation of Cyp17a1 1 0.25 0.06 0.17
87 INT13723 Negative_regulation of Positive_regulation of WT1 1 0.03 1.26 0.17
88 INT187609 Negative_regulation of Phosphorylation of Cyp17a1 1 0.13 0.06 0.17
89 INT10575 Positive_regulation of Transcription of Cyp11a1 1 0.05 0 0.17
90 INT102793 Regulation of Phosphorylation of Egr1 1 0.33 0 0.17
91 INT187610 Positive_regulation of Cyp17a1 1 0.14 0.06 0.17
92 INT319048 Transcription of WT1 2 0.56 1.87 0.16
93 INT10572 Positive_regulation of Positive_regulation of Cyp11a1 1 0.05 0 0.16
94 INT101208 Positive_regulation of Gene_expression of Wt1 3 0.47 3.08 0.15
95 INT115825 Positive_regulation of Gene_expression of Por 2 0.22 0.47 0.12
96 INT178195 Localization of Wt1 4 0.69 2.64 0.1
97 INT115833 Negative_regulation of Transcription of Por 1 0.20 0.52 0.09
98 INT115828 Negative_regulation of Gene_expression of Por 1 0.20 0.52 0.09
99 INT245059 Localization of PAX8 1 0.51 1.43 0.08
100 INT168975 Binding of Wt1 14 0.43 7.37 0.07
101 INT166389 Binding of WT1 7 0.36 8.25 0.07
102 INT339183 Positive_regulation of GATA6 1 0.16 0.66 0.06
103 INT197611 Regulation of Regulation of Pgr 1 0.16 0 0.06
104 INT307902 Negative_regulation of Localization of Wt1 1 0.34 0.21 0.05
105 INT140315 Regulation of Positive_regulation of Cyp11a1 1 0.19 0.07 0.05
106 INT176561 Gene_expression of Cyp17a1 3 0.25 1.38 0.04
107 INT201049 Negative_regulation of SLC5A5 5 0.05 2.25 0.03
108 INT248540 Positive_regulation of Gata4 2 0.23 0.95 0.03
109 INT181604 Localization of WT1 1 0.63 1.41 0.03
110 INT27939 Positive_regulation of Negative_regulation of Pgr 6 0.27 1.44 0
111 INT201051 Gene_expression of SLC5A5 6 0.09 2.08 0
112 INT285960 Negative_regulation of WT1 6 0.47 10.02 0
113 INT276530 Negative_regulation of Wt1 5 0.53 2.97 0
114 INT97180 Regulation of Transcription of Pgr 5 0.38 2.2 0
115 INT201053 Positive_regulation of Gene_expression of SLC5A5 3 0.06 1.18 0
116 INT285959 Negative_regulation of Gene_expression of WT1 3 0.46 4.9 0
117 INT274404 Binding of Gata4 2 0.16 0.89 0
118 INT276519 Regulation of Wt1 2 0.24 1.7 0
119 INT201052 Negative_regulation of Gene_expression of SLC5A5 2 0.07 0.55 0
120 INT276550 Transcription of Wt1 2 0.66 1.35 0
121 INT218972 Positive_regulation of Binding of Pgr 2 0.28 0.46 0
122 INT252985 Transcription of SLC5A5 1 0.05 0.35 0
123 INT197609 Positive_regulation of Transcription of Pgr 1 0.29 0.07 0
124 INT341925 Positive_regulation of Localization of SLC5A5 1 0.03 0.17 0
125 INT217818 Gene_expression of GATA6 1 0.17 1.07 0
126 INT276547 Positive_regulation of Binding of Wt1 1 0.63 0.29 0
127 INT307906 Negative_regulation of Transcription of Wt1 1 0.54 1.3 0
128 INT252987 Positive_regulation of SLC5A5 1 0.03 0.35 0
129 INT280013 Binding of SLC5A5 1 0.01 1.03 0
130 INT213932 Negative_regulation of Negative_regulation of Cyp19a1 1 0.31 0.7 0
131 INT194353 Negative_regulation of Binding of Cyp19a1 1 0.15 0 0
132 INT197610 Negative_regulation of Negative_regulation of Pgr 1 0.25 0.49 0
133 INT197604 Positive_regulation of Regulation of Pgr 1 0.29 0.49 0
134 INT276551 Positive_regulation of Localization of Wt1 1 0.45 0 0
135 INT197598 Negative_regulation of Localization of Pgr 1 0.21 0.28 0
136 INT197597 Positive_regulation of Localization of Pgr 1 0.25 0.29 0
137 INT276534 Negative_regulation of Binding of Wt1 1 0.38 0 0
138 INT259446 Positive_regulation of Gene_expression of Cyp11a1 1 0.28 0 0
139 INT341927 Localization of SLC5A5 1 0.04 0.17 0
140 INT319051 Regulation of Positive_regulation of WT1 1 0.36 1.11 0
141 INT272385 Negative_regulation of Positive_regulation of Pgr 1 0.04 0.21 0
142 INT181811 Localization of Gata4 1 0.54 0.3 0
143 INT328768 Positive_regulation of Gene_expression of Gata6 1 0.19 0.61 0
144 INT176563 Binding of Cyp17a1 1 0.13 0.32 0
145 INT307903 Negative_regulation of Gene_expression of Wt1 1 0.39 1.31 0
146 INT339154 Negative_regulation of GATA6 1 0.14 0.86 0
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