GO:0071392

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Name cellular response to estradiol stimulus
Categary Process
Go Slim No
Go Link GO:0071392
Unique Molecular Interactions 271
Total Molecular Interactions 371
Total Single Events 3902
Pain Genes Associated 16

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular response to estradiol stimulus. They are ordered first by their pain relevance and then by number of times they were reported for cellular response to estradiol stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95
2 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
3 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
4 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
5 INT155460 Tnfrsf1a Positive_regulation of Positive_regulation of Nfkb1 1 0.42 2.39 1.82
6 INT192161 Mmp14 Positive_regulation of Mmp2 2 0.19 1.23 1.81
7 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
8 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
9 INT155459 Tnfrsf1a Positive_regulation of Nfkb1 1 0.42 2.45 1.63
10 INT40827 Sstr1 Negative_regulation of Localization of Gh1 1 0.13 0 1.58
11 INT130838 Gfap Positive_regulation of Aqp4 1 0.51 1.9 1.56
12 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54
13 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
14 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
15 INT19012 Ghsr Negative_regulation of Localization of Sstr1 1 0.10 0 1.44
16 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
17 INT112097 Sstr1 Positive_regulation of Adarb1 1 0.02 0.15 1.29
18 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
19 INT172141 IL10 Negative_regulation of Gene_expression of HLA-DRA 2 0.14 0.89 1.23
20 INT70036 LTA Regulation of Negative_regulation of IL10 1 0.03 1.42 1.21
21 INT70046 IL12A Regulation of IL10 1 0.07 1.42 1.21
22 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
23 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
24 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
25 INT70041 LTA Regulation of IL10 1 0.03 1.42 1.21
26 INT70034 IL12A Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
27 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
28 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18
29 INT203103 ACAN Negative_regulation of Gene_expression of IL10 1 0.02 1.31 1.12
30 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
31 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
32 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
33 INT120313 Gnrhr Negative_regulation of Mmp2 1 0.03 0.85 1.07
34 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
35 INT292531 Il10 Negative_regulation of Positive_regulation of Mapk14 1 0.15 1.13 1.06
36 INT5107 Gal Positive_regulation of Localization of Sstr1 1 0.09 0 0.98
37 INT292530 Il10 Negative_regulation of Localization of Il1a 1 0.06 1.09 0.97
38 INT5104 Gal Positive_regulation of Sstr1 1 0.06 0 0.96
39 INT277831 Binding of TNFRSF1A and NPEPPS 1 0.01 1.1 0.87
40 INT226337 Binding of IL10 and IL10RA 2 0.24 2.51 0.85
41 INT221034 IL10 Positive_regulation of Localization of CCL18 1 0.19 1.3 0.84
42 INT192158 Binding of Mmp2 and Mmp9 1 0.21 0.94 0.83
43 INT108811 Esr2 Positive_regulation of Binding of Oprm1 1 0.46 0.44 0.79
44 INT130286 MC1R Positive_regulation of Localization of IL10 1 0.24 0.07 0.79
45 INT13428 Gabrd Regulation of Localization of Sstr2 1 0.31 0 0.79
46 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78
47 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
48 INT221415 IRF6 Positive_regulation of Gene_expression of IL10 2 0.05 1.73 0.75
49 INT176473 IL10 Positive_regulation of Gene_expression of PECAM1 1 0.05 1.1 0.75
50 INT308176 TNF Regulation of Tnfrsf1a 1 0.05 1.19 0.75
51 INT40826 Pomc Negative_regulation of Binding of Sstr1 1 0.05 0 0.74
52 INT150997 Sfpq Positive_regulation of Gene_expression of Il10 1 0.09 0.71 0.74
53 INT144453 Binding of GPM6A and SSTR2 1 0.02 0 0.74
54 INT266765 IL2 Positive_regulation of Localization of IL10 1 0.01 1.03 0.72
55 INT194685 MAPK1 Regulation of Gene_expression of IL10 1 0.06 1.18 0.7
56 INT104835 IRF6 Positive_regulation of IL10 4 0.32 0.91 0.69
57 INT172146 IL10 Positive_regulation of Protein_catabolism of TNF 2 0.15 1.69 0.69
58 INT186123 Binding of GIF and IL10 1 0.23 1.17 0.69
59 INT263049 Positive_regulation of Binding of Mmp2 and Mmp9 1 0.35 0.83 0.69
60 INT172142 IL10 Positive_regulation of Protein_catabolism of IL1B 2 0.03 1.69 0.68
61 INT155457 Tnfrsf1a Positive_regulation of Mapk14 1 0.20 1.17 0.67
62 INT152299 Mmp2 Negative_regulation of Tsc22d1 1 0.16 0.16 0.66
63 INT152297 Mmp2 Negative_regulation of Mmp9 1 0.39 0.16 0.65
64 INT155458 Tnfrsf1a Regulation of Gene_expression of Il6 1 0.22 1.11 0.63
65 INT314051 THL Negative_regulation of Localization of Mmp2 1 0.14 1.1 0.62
66 INT95431 Il1a Regulation of Mmp2 1 0.48 0.25 0.61
67 INT154530 Positive_regulation of Ifng Negative_regulation of Il10 1 0.33 0.63 0.61
68 INT95433 Mmp3 Regulation of Mmp2 1 0.17 0.24 0.6
69 INT154531 Ifng Negative_regulation of Il10 1 0.30 0.61 0.6
70 INT109802 Binding of Esr2 and Oprl1 1 0.22 0.1 0.59
71 INT172145 IL10 Negative_regulation of Gene_expression of CSF2 1 0.04 0.69 0.59
72 INT130287 POMC Regulation of Localization of IL10 1 0.12 0.1 0.59
73 INT181471 Binding of Il10 and Ptbp1 1 0.05 2.14 0.58
74 INT342624 VEGFA Negative_regulation of Mmp2 1 0.09 1.54 0.58
75 INT342619 Mmp2 Negative_regulation of Timp2 1 0.42 1.48 0.57
76 INT303652 Binding of SST and SSTR2 1 0.26 0.46 0.57
77 INT203105 MMP3 Negative_regulation of Gene_expression of IL10 1 0.06 0.69 0.56
78 INT286349 IRF6 Positive_regulation of Localization of IL10 1 0.03 1.22 0.55
79 INT351332 Positive_regulation of Il4 Positive_regulation of Gene_expression of Il10 1 0.09 1.78 0.53
80 INT314043 THL Negative_regulation of Mmp2 1 0.22 2.11 0.53
81 INT329722 Binding of Il10rb and Il10 1 0.00 0.79 0.51
82 INT329721 Positive_regulation of Binding of Il10rb and Il10 1 0.00 0.79 0.51
83 INT271874 IL10 Negative_regulation of TNF 1 0.07 0.78 0.5
84 INT235956 Binding of Aqp4 and NMO-IgG 1 0.04 4.53 0.5
85 INT150921 ZNF398 Negative_regulation of Gene_expression of Mmp2 1 0.00 0.46 0.5
86 INT230532 LILRB1 Positive_regulation of Gene_expression of Mmp2 1 0.14 1.04 0.5
87 INT194676 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of IL10 1 0.05 0.34 0.5
88 INT285344 Il10 Negative_regulation of Gene_expression of Tnf 1 0.15 1.91 0.49
89 INT161166 Binding of Aqp4 and Igh-6 1 0.03 2.58 0.49
90 INT70930 Sstr2 Regulation of Localization of Gh1 1 0.15 0 0.49
91 INT271873 IL10 Regulation of Gene_expression of IK 1 0.00 0.81 0.47
92 INT271872 IL10 Regulation of IK 1 0.00 0.81 0.47
93 INT314053 VEGFA Positive_regulation of Gene_expression of Mmp2 1 0.02 0.2 0.47
94 INT252634 Binding of TNF and Tnfrsf1a 4 0.02 2.4 0.46
95 INT72088 IL10 Positive_regulation of POMC 1 0.15 0 0.46
96 INT138152 IL6 Positive_regulation of Transcription of Mmp2 1 0.00 0.23 0.46
97 INT138154 IL1B Positive_regulation of Transcription of Mmp2 1 0.04 0.23 0.46
98 INT327995 Positive_regulation of TRPV1 Positive_regulation of Tnfrsf1a 1 0.16 0.63 0.46
99 INT323903 CNDP1 Positive_regulation of IL10 1 0.00 0.9 0.46
100 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
101 INT303651 Binding of SSTR2 and SSTR5 1 0.24 0.23 0.45
102 INT323906 ACCS Positive_regulation of IL10 1 0.05 0.9 0.45
103 INT314050 THL Negative_regulation of Transcription of Mmp2 1 0.16 0.81 0.44
104 INT352986 IL10 Negative_regulation of Gene_expression of Il6 1 0.01 1 0.43
105 INT316121 IL10 Regulation of Gene_expression of HLA-DRA 1 0.09 0.46 0.42
106 INT314042 THL Negative_regulation of Gene_expression of Mmp2 1 0.19 2.97 0.42
107 INT261374 Nsdhl Regulation of Esr2 1 0.05 0.76 0.41
108 INT294780 IL6 Positive_regulation of IL10 2 0.10 1.26 0.39
109 INT227906 IL10 Regulation of Gene_expression of IL1B 1 0.07 0.57 0.38
110 INT179851 Il11 Positive_regulation of Mmp2 1 0.04 0 0.38
111 INT227909 IL10 Regulation of Gene_expression of TNF 1 0.21 0.57 0.38
112 INT342622 Binding of MMP14 and Mmp2 1 0.39 1.15 0.37
113 INT60817 Binding of Sstr1 and Bcl2l11 1 0.06 0 0.37
114 INT342617 Binding of Col18a1 and Mmp2 1 0.11 1.15 0.37
115 INT245328 Binding of Esr2 and Pgr 1 0.03 0.41 0.37
116 INT179201 NLRP1 Regulation of Gene_expression of IL10 1 0.06 0.77 0.36
117 INT104836 IGKV2OR2-1 Negative_regulation of Gene_expression of IL10 1 0.01 0 0.36
118 INT227904 TNFRSF1A Regulation of TNF 1 0.01 0.41 0.36
119 INT77791 fut10 Regulation of Regulation of Tnfrsf1a 1 0.02 0.85 0.36
120 INT194641 Binding of IL10 and TNF 2 0.14 1.09 0.35
121 INT144049 IL10 Negative_regulation of Gene_expression of PTGES 1 0.35 0.47 0.35
122 INT140183 Il4 Positive_regulation of Gene_expression of Il10 1 0.12 0.73 0.34
123 INT336336 Il10 Regulation of Il13 1 0.04 0.67 0.34
124 INT140181 Gene_expression of Il4 Positive_regulation of Gene_expression of Il10 1 0.17 0.73 0.34
125 INT266806 Hand2 Regulation of Gene_expression of IL10 1 0.00 1.23 0.32
126 INT77792 fut10 Negative_regulation of Positive_regulation of Tnfrsf1a 1 0.04 0.82 0.32
127 INT307019 MT1JP Positive_regulation of Gene_expression of IL10 1 0.03 0.58 0.32
128 INT303446 Timp1 Negative_regulation of Mmp2 1 0.19 0.33 0.31
129 INT326090 Binding of Erbb2 and Mmp2 1 0.09 1.39 0.31
130 INT235958 Binding of Ighg1 and Aqp4 1 0.14 1.32 0.3
131 INT207823 SSTR2 Negative_regulation of Localization of GCG 1 0.06 0 0.29
132 INT227910 TNF Positive_regulation of Gene_expression of IL10 1 0.22 0.68 0.29
133 INT328222 Mmp2 Regulation of Positive_regulation of Mmp13 1 0.05 0.69 0.28
134 INT194682 Negative_regulation of MAPK1 Positive_regulation of Gene_expression of IL10 1 0.05 0.17 0.27
135 INT120856 PRL Positive_regulation of Localization of IL10 1 0.29 0.5 0.26
136 INT328064 IL10 Positive_regulation of FAAH 1 0.05 1.48 0.26
137 INT235959 Nqo1 Positive_regulation of Localization of Aqp4 1 0.02 1.39 0.26
138 INT136367 RYBP Negative_regulation of Positive_regulation of Il10 1 0.00 0.37 0.26
139 INT148223 CXCL14 Regulation of Localization of Mmp2 1 0.01 0.71 0.26
140 INT226361 Binding of IL10 and IL22RA1 1 0.00 0.17 0.26
141 INT5109 Gal Regulation of Localization of Sstr1 1 0.06 0 0.25
142 INT244687 Mmp14 Positive_regulation of Mmp2 1 0.23 0.48 0.25
143 INT203165 Binding of IL10 and PTGER2 1 0.01 0.5 0.25
144 INT113419 IL10 Negative_regulation of Gene_expression of IL18 1 0.31 0.86 0.24
145 INT197590 Esr2 Positive_regulation of Negative_regulation of Pgr 1 0.16 0 0.24
146 INT159163 Binding of Esr2 and Regulation of Gper 1 0.41 0.27 0.23
147 INT168709 Ifng Regulation of Il10 1 0.02 0.3 0.23
148 INT234755 IL10 Positive_regulation of IFN1@ 1 0.08 0.68 0.23
149 INT194702 MAPK1 Negative_regulation of Gene_expression of IL10 1 0.05 0.16 0.23
150 INT261389 Nsdhl Positive_regulation of Esr2 1 0.06 1.04 0.23
151 INT352163 SNRPA Positive_regulation of Localization of IL10 1 0.06 0.87 0.23
152 INT227905 IL10 Positive_regulation of Gene_expression of TIMP1 1 0.01 0.48 0.22
153 INT170993 IL10 Positive_regulation of Gene_expression of CCR1 1 0.12 0.34 0.22
154 INT221022 IL10 Positive_regulation of CCL18 1 0.19 0.38 0.22
155 INT285342 Mtx1 Regulation of Il10 1 0.03 0.78 0.22
156 INT330382 IFNA1 Positive_regulation of Gene_expression of IL10 1 0.06 0.83 0.21
157 INT60523 Binding of IL1B and TNFRSF1A 1 0.25 1.73 0.21
158 INT209857 IL10 Negative_regulation of Gene_expression of CD36 1 0.31 0.16 0.2
159 INT226338 IL19 Positive_regulation of Gene_expression of IL10 1 0.01 0.56 0.2
160 INT226351 IL19 Positive_regulation of IL10 1 0.01 0.55 0.2
161 INT286348 IL8 Positive_regulation of IL10 1 0.08 0.18 0.19
162 INT221023 IL13 Positive_regulation of Gene_expression of IL10 1 0.01 0.13 0.19
163 INT262905 Binding of IL10 and MDD1 1 0.40 1.03 0.19
164 INT221021 IL4 Positive_regulation of Gene_expression of IL10 1 0.01 0.13 0.19
165 INT222499 Il10 Regulation of Positive_regulation of Hpse 1 0.00 0.8 0.19
166 INT123923 asa Positive_regulation of Il10 1 0.04 1.97 0.19
167 INT264189 HR Positive_regulation of Gene_expression of IL10 1 0.00 1.48 0.19
168 INT221032 IL10 Positive_regulation of Gene_expression of CCL18 1 0.14 0.13 0.19
169 INT40838 Sstr1 Negative_regulation of Positive_regulation of Vip 1 0.10 0 0.19
170 INT323134 Binding of IL10 and IL12A 1 0.06 0.55 0.18
171 INT198382 Binding of AR and SRD5A1 2 0.06 0.84 0.17
172 INT316129 Binding of HLA-DRA and IL10 1 0.12 3.1 0.17
173 INT316132 IL10 Regulation of MARCH1 1 0.11 2.12 0.17
174 INT316122 IL10 Regulation of Gene_expression of MARCH1 1 0.19 2.12 0.17
175 INT220531 Atf3 Negative_regulation of Gene_expression of Mmp2 1 0.02 1.09 0.16
176 INT353036 IL4 Positive_regulation of Localization of IL10 1 0.03 0.99 0.16
177 INT303659 SSTR2 Negative_regulation of Gene_expression of SST 1 0.30 0.94 0.16
178 INT104829 Negative_regulation of IRF6 Positive_regulation of IL10 1 0.30 0 0.16
179 INT303657 Gene_expression of SSTR2 Negative_regulation of Gene_expression of SST 1 0.30 0.94 0.16
180 INT301121 Tgm7 Regulation of Gene_expression of Mmp2 1 0.52 2.53 0.16
181 INT85274 SGCG Positive_regulation of Mmp2 1 0.09 0.46 0.16
182 INT220515 Il10 Negative_regulation of Gene_expression of Mmp2 1 0.01 1.1 0.16
183 INT86951 Ads3 Positive_regulation of Gene_expression of Il10 1 0.00 0.42 0.16
184 INT198307 IL10 Positive_regulation of Gene_expression of IGHG3 2 0.01 1.21 0.15
185 INT250908 Binding of Mmp2 and Tsp1 1 0.04 0.09 0.15
186 INT104830 IGKV2OR2-1 Regulation of Gene_expression of IL10 1 0.00 0 0.15
187 INT247851 Negative_regulation of Aqp4 Negative_regulation of Positive_regulation of Narfl 1 0.09 1.78 0.15
188 INT250906 Binding of Mmp2 and Thbs2 1 0.06 0.09 0.15
189 INT104832 Binding of IL10 and NFKB1 1 0.15 0 0.15
190 INT139336 Il1b Regulation of Tnfrsf1a 1 0.27 1.3 0.14
191 INT139338 Cts8 Regulation of Tnfrsf1a 1 0.05 1.3 0.14
192 INT314039 THL Negative_regulation of Binding of Mmp2 1 0.16 1.62 0.14
193 INT139346 Cts8 Regulation of Gene_expression of Tnfrsf1a 1 0.05 1.3 0.14
194 INT221031 IL10 Positive_regulation of Binding of TNF 1 0.05 0.28 0.14
195 INT220305 Binding of IL6 and IL10 1 0.00 0.51 0.14
196 INT139347 Il1b Regulation of Gene_expression of Tnfrsf1a 1 0.27 1.3 0.14
197 INT235961 Binding of Nqo1 and Aqp4 1 0.02 0.9 0.14
198 INT250911 Thbs2 Regulation of Mmp2 1 0.05 0.3 0.13
199 INT296031 Negative_regulation of TGFB1 Regulation of IL10 1 0.01 1.01 0.13
200 INT330370 Positive_regulation of Binding of IL10 and Il4 1 0.01 0.47 0.13

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular response to estradiol stimulus. They are ordered first by their pain relevance and then by number of times they were reported in cellular response to estradiol stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52
2 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84
3 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72
4 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5
5 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5
6 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68
7 INT130837 Gene_expression of Aqp4 205 0.78 151.23 29.63
8 INT5097 Localization of Sstr1 30 0.64 0.38 27.92
9 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66
10 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25
11 INT15511 Gene_expression of Tnfrsf1a 84 0.76 63.3 24.03
12 INT74423 Localization of IL10 91 0.80 61.6 22.95
13 INT12114 Positive_regulation of Tnfrsf1a 46 0.69 36.26 22.54
14 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73
15 INT50814 Positive_regulation of Mmp2 72 0.68 51.37 20.42
16 INT69304 Negative_regulation of Il10 47 0.59 36.88 19.79
17 INT74286 Regulation of Il10 42 0.44 28.06 19.44
18 INT72564 Localization of Il10 41 0.78 28.62 17.6
19 INT48892 Transcription of Il10 31 0.71 27.26 16.77
20 INT86950 Negative_regulation of Gene_expression of Il10 26 0.42 18.92 12.73
21 INT70050 Negative_regulation of IL10 56 0.58 37.45 12.39
22 INT86291 Negative_regulation of Mmp2 33 0.57 20.38 10.76
23 INT74681 Positive_regulation of Gene_expression of Mmp2 23 0.55 15.58 10.74
24 INT13423 Localization of Sstr2 17 0.78 0.56 10.47
25 INT81929 Negative_regulation of Gene_expression of IL10 41 0.57 27.99 9.87
26 INT99495 Gene_expression of SRD5A1 14 0.77 5 9.21
27 INT73497 Regulation of IL10 33 0.45 22.6 9.19
28 INT77790 Positive_regulation of Gene_expression of Tnfrsf1a 16 0.67 15.88 8.5
29 INT18194 Positive_regulation of Localization of Sstr1 5 0.40 0 8.41
30 INT111903 Regulation of Mmp2 9 0.61 3.95 7.98
31 INT103289 Binding of Il10 15 0.35 13.67 7.42
32 INT136304 Negative_regulation of Aqp4 54 0.59 48.42 7.4
33 INT111398 Localization of Mmp2 37 0.76 23.78 7.17
34 INT91906 Regulation of Gene_expression of Il10 13 0.58 8.92 7.06
35 INT31333 Gene_expression of Esr2 19 0.69 8.78 6.83
36 INT60527 Transcription of IL10 16 0.56 13.57 6.42
37 INT123551 Regulation of Mmp2 17 0.57 11.6 6
38 INT5094 Negative_regulation of Localization of Sstr1 8 0.36 0 5.98
39 INT15132 Gene_expression of TNFRSF1A 33 0.75 20.09 5.93
40 INT87468 Negative_regulation of Mmp2 24 0.57 10.79 5.55
41 INT40719 Binding of Sstr1 7 0.25 0.1 5.49
42 INT18195 Regulation of Localization of Sstr1 5 0.33 0 5.24
43 INT126751 Regulation of Gene_expression of IL10 16 0.44 10.84 5.22
44 INT142162 Binding of IL10 30 0.37 21.9 4.84
45 INT18193 Positive_regulation of Sstr1 6 0.31 1.82 4.8
46 INT130290 Positive_regulation of Localization of IL10 16 0.47 9.38 4.75
47 INT29502 Localization of Mmp2 18 0.79 3.49 4.64
48 INT118230 Binding of Tnfrsf1a 15 0.42 7.63 4.39
49 INT143337 Binding of Aqp4 30 0.40 23.73 4.24
50 INT24805 Gene_expression of Sstr1 4 0.37 1 4.06
51 INT140542 Gene_expression of SSTR2 18 0.65 13.58 3.94
52 INT77385 Gene_expression of Esr2 18 0.75 4.69 3.92
53 INT169748 Positive_regulation of Gene_expression of Aqp4 38 0.69 34.29 3.79
54 INT86293 Positive_regulation of Gene_expression of Mmp2 21 0.64 11.69 3.79
55 INT98624 Regulation of Aqp4 27 0.62 30.76 3.77
56 INT225965 Localization of Aqp4 26 0.81 18.85 3.75
57 INT99889 Transcription of SRD5A1 5 0.71 1.45 3.74
58 INT13425 Positive_regulation of Localization of Sstr2 4 0.67 0.19 3.65
59 INT77786 Negative_regulation of Tnfrsf1a 5 0.56 5.03 3.58
60 INT74157 Negative_regulation of Positive_regulation of Il10 5 0.43 5.83 3.56
61 INT77788 Regulation of Tnfrsf1a 14 0.57 11.24 3.53
62 INT130836 Transcription of Aqp4 6 0.72 5.93 3.52
63 INT89521 Positive_regulation of Localization of Il10 8 0.44 6.45 3.51
64 INT40653 Gene_expression of Sstr2 6 0.54 1.28 3.43
65 INT96700 Positive_regulation of Positive_regulation of Tnfrsf1a 6 0.69 3.93 3.42
66 INT52899 Positive_regulation of TNFRSF1A 16 0.46 19.04 3.34
67 INT48893 Positive_regulation of Transcription of Il10 3 0.69 4.29 3.29
68 INT130835 Positive_regulation of Transcription of Aqp4 3 0.68 4.5 3.28
69 INT165821 Positive_regulation of Aqp4 27 0.70 24.37 3.22
70 INT13422 Regulation of Localization of Sstr2 4 0.44 0 3.1
71 INT138141 Transcription of Mmp2 10 0.64 6.52 2.99
72 INT16616 Negative_regulation of SRD5A1 44 0.57 34.81 2.96
73 INT115579 Positive_regulation of Positive_regulation of Il10 7 0.68 4.82 2.91
74 INT50320 Transcription of Sstr1 3 0.43 0.53 2.58
75 INT19006 Negative_regulation of Sstr1 5 0.28 0.1 2.55
76 INT103603 Negative_regulation of Gene_expression of Mmp2 16 0.51 12.29 2.47
77 INT13421 Positive_regulation of Sstr2 5 0.54 0.46 2.32
78 INT225966 Regulation of Gene_expression of Aqp4 18 0.62 20.39 2.3
79 INT18196 Regulation of Sstr1 3 0.34 0 2.26
80 INT48894 Negative_regulation of Transcription of Il10 5 0.26 2.79 2.22
81 INT127740 Regulation of Localization of Il10 3 0.60 0.65 2.18
82 INT180923 Negative_regulation of Localization of Mmp2 6 0.46 7.84 2.17
83 INT49769 Binding of SSTR2 4 0.48 1.39 2.14
84 INT263046 Negative_regulation of Gene_expression of Mmp2 7 0.34 5.98 2.09
85 INT342815 Positive_regulation of Transcription of SRD5A1 1 0.49 0.33 2.04
86 INT46332 Binding of Mmp2 10 0.34 5.63 2
87 INT109800 Binding of Esr2 8 0.42 1.79 1.93
88 INT148705 Binding of TNFRSF1A 8 0.38 5.19 1.81
89 INT152292 Regulation of Gene_expression of Mmp2 6 0.61 3.46 1.76
90 INT153918 Binding of Esr2 3 0.33 2.56 1.7
91 INT40863 Negative_regulation of Sstr2 2 0.57 0.15 1.7
92 INT107485 Regulation of Sstr2 1 0.35 1.16 1.65
93 INT30076 Negative_regulation of Esr2 1 0.01 0 1.63
94 INT86294 Regulation of Gene_expression of Mmp2 3 0.60 1.12 1.62
95 INT133443 Transcription of Mmp2 8 0.69 2.48 1.61
96 INT164480 Negative_regulation of Gene_expression of Aqp4 14 0.58 10.84 1.52
97 INT262908 Negative_regulation of Localization of IL10 5 0.43 4 1.5
98 INT60528 Negative_regulation of TNFRSF1A 6 0.42 4.86 1.45
99 INT86292 Positive_regulation of Positive_regulation of Mmp2 4 0.46 3.09 1.4
100 INT107924 Localization of Tnfrsf1a 5 0.70 3.86 1.37
101 INT317979 Positive_regulation of Transcription of Mmp2 4 0.46 2.63 1.37
102 INT77785 Negative_regulation of Gene_expression of Tnfrsf1a 4 0.56 3.1 1.35
103 INT238074 Negative_regulation of Positive_regulation of Mmp2 4 0.34 1.79 1.31
104 INT198387 Regulation of SRD5A1 2 0.60 1.29 1.26
105 INT77782 Negative_regulation of Positive_regulation of Tnfrsf1a 3 0.41 1.21 1.16
106 INT182847 Regulation of Binding of Il10 2 0.41 1.26 1.15
107 INT265004 Positive_regulation of Binding of Tnfrsf1a 1 0.36 1.23 1.1
108 INT164533 Positive_regulation of Regulation of Il10 4 0.46 2.09 1.06
109 INT154493 Regulation of Gene_expression of SRD5A1 3 0.45 0.58 1.03
110 INT122647 Transcription of Tnfrsf1a 5 0.60 2.63 1.02
111 INT66862 Regulation of Esr2 3 0.24 1.56 1.01
112 INT91907 Positive_regulation of Negative_regulation of Il10 2 0.48 1.37 1
113 INT139333 Regulation of Gene_expression of Tnfrsf1a 3 0.40 5.41 0.98
114 INT144461 Negative_regulation of SSTR2 2 0.49 1.03 0.98
115 INT180925 Positive_regulation of Localization of Mmp2 4 0.54 3.21 0.95
116 INT29501 Positive_regulation of Localization of Mmp2 3 0.60 0.42 0.94
117 INT74424 Regulation of Localization of IL10 3 0.31 0.91 0.93
118 INT47039 Regulation of SFRP1 14 0.62 7.44 0.92
119 INT29500 Regulation of Localization of Mmp2 3 0.53 0.47 0.92
120 INT54432 Transcription of Sstr2 3 0.09 0 0.89
121 INT171008 Positive_regulation of Transcription of IL10 1 0.15 1.33 0.89
122 INT152290 Regulation of Transcription of Mmp2 1 0.27 0.15 0.8
123 INT182059 Positive_regulation of Positive_regulation of IL10 3 0.17 1.86 0.77
124 INT158075 Positive_regulation of Esr2 1 0.28 0.5 0.77
125 INT98131 Regulation of TNFRSF1A 5 0.31 5.28 0.76
126 INT235953 Regulation of Binding of Aqp4 4 0.45 4.4 0.76
127 INT235951 Positive_regulation of Positive_regulation of Aqp4 4 0.57 5.13 0.75
128 INT123773 Positive_regulation of Positive_regulation of Mmp2 2 0.17 1.83 0.75
129 INT265557 Protein_catabolism of Mmp2 3 0.55 3.15 0.73
130 INT266797 Negative_regulation of Negative_regulation of Mmp2 1 0.05 0.96 0.7
131 INT47038 Gene_expression of SFRP1 14 0.67 9.6 0.63
132 INT327768 Regulation of Transcription of IL10 1 0.17 0.13 0.61
133 INT60816 Binding of Sstr2 1 0.05 0 0.59
134 INT86444 Positive_regulation of Gene_expression of Sstr1 1 0.25 0.15 0.57
135 INT283569 Protein_catabolism of Mmp2 5 0.77 3.25 0.56
136 INT257406 Localization of TNFRSF1A 3 0.46 2.6 0.55
137 INT244679 Binding of Mmp2 4 0.30 3.75 0.54
138 INT342614 Positive_regulation of Binding of Mmp2 1 0.46 0.6 0.54
139 INT342811 Positive_regulation of Gene_expression of SRD5A1 1 0.45 0.22 0.5
140 INT30075 Localization of Esr2 2 0.01 0.78 0.49
141 INT135366 Localization of SFRP1 4 0.75 1.82 0.47
142 INT145144 Positive_regulation of Negative_regulation of Mmp2 1 0.11 0.7 0.46
143 INT323141 Positive_regulation of Negative_regulation of IL10 1 0.37 1.06 0.44
144 INT305077 Localization of CRHBP 1 0.76 0.28 0.44
145 INT244683 Regulation of Positive_regulation of Mmp2 2 0.36 0.78 0.43
146 INT109801 Transcription of Esr2 2 0.69 2.08 0.41
147 INT352983 Protein_catabolism of IL10 1 0.13 1.04 0.41
148 INT348631 Regulation of Esr2 1 0.40 0.87 0.4
149 INT279364 Regulation of Negative_regulation of IL10 1 0.04 0.49 0.39
150 INT279367 Negative_regulation of Regulation of IL10 1 0.06 0.49 0.39
151 INT186535 Negative_regulation of Gene_expression of Esr2 2 0.25 1.07 0.38
152 INT253242 Positive_regulation of Transcription of Tnfrsf1a 2 0.44 0.77 0.38
153 INT77783 Regulation of Positive_regulation of Tnfrsf1a 1 0.44 0.85 0.36
154 INT299223 Negative_regulation of Transcription of Aqp4 3 0.59 1.36 0.35
155 INT235950 Regulation of Regulation of Aqp4 1 0.37 1.96 0.34
156 INT202106 Positive_regulation of Gene_expression of TNFRSF1A 3 0.22 1.17 0.31
157 INT66863 Regulation of Gene_expression of Esr2 1 0.03 0 0.31
158 INT102992 Regulation of Negative_regulation of SRD5A1 4 0.60 3.59 0.29
159 INT247097 Binding of CRHBP 3 0.34 0.4 0.28
160 INT114603 Negative_regulation of Localization of Il10 1 0.21 0.61 0.28
161 INT299798 Negative_regulation of Transcription of IL10 1 0.07 0.73 0.27
162 INT29504 Negative_regulation of Localization of Mmp2 1 0.58 0.13 0.26
163 INT247863 Positive_regulation of Negative_regulation of Aqp4 3 0.45 2.63 0.25
164 INT235946 Positive_regulation of Localization of Aqp4 1 0.41 1.32 0.25
165 INT148219 Regulation of Localization of Mmp2 1 0.02 0.69 0.25
166 INT247870 Negative_regulation of Localization of Aqp4 3 0.43 2 0.24
167 INT114896 Negative_regulation of Positive_regulation of TNFRSF1A 1 0.17 0.83 0.23
168 INT126794 Binding of SRD5A1 2 0.36 3.26 0.22
169 INT235947 Regulation of Localization of Aqp4 1 0.37 1.25 0.22
170 INT303672 Negative_regulation of Gene_expression of SSTR2 1 0.49 0.95 0.21
171 INT291081 Positive_regulation of Protein_catabolism of Mmp2 1 0.29 0.96 0.2
172 INT291083 Negative_regulation of Protein_catabolism of Mmp2 1 0.24 0.96 0.2
173 INT140543 Transcription of SSTR2 2 0.22 1.25 0.19
174 INT159640 Negative_regulation of Regulation of Aqp4 1 0.42 0.78 0.18
175 INT182061 Regulation of Positive_regulation of IL10 1 0.12 1.07 0.18
176 INT269999 Regulation of Gene_expression of TNFRSF1A 2 0.44 0.53 0.17
177 INT303677 Positive_regulation of SSTR2 1 0.42 0.56 0.16
178 INT303668 Positive_regulation of Gene_expression of SSTR2 1 0.42 0.66 0.16
179 INT231956 Phosphorylation of IL10 1 0.26 0.07 0.16
180 INT104841 Negative_regulation of Positive_regulation of IL10 1 0.27 0 0.14
181 INT340783 Transcription of TNFRSF1A 1 0.17 0.37 0.13
182 INT332570 Phosphorylation of Aqp4 1 0.59 0.9 0.13
183 INT219179 Positive_regulation of Regulation of IL10 1 0.08 0.45 0.13
184 INT340784 Positive_regulation of Transcription of TNFRSF1A 1 0.17 0.37 0.13
185 INT236875 Localization of SRD5A1 2 0.73 0.8 0.11
186 INT248410 Negative_regulation of Regulation of Il10 1 0.27 0.38 0.11
187 INT265543 Negative_regulation of Transcription of Mmp2 1 0.09 1.27 0.1
188 INT339391 Regulation of Positive_regulation of Il10 1 0.26 0.31 0.09
189 INT261361 Negative_regulation of Esr2 1 0.15 0.67 0.09
190 INT265553 Negative_regulation of Transcription of Mmp2 2 0.30 1.18 0.08
191 INT98128 Positive_regulation of Regulation of TNFRSF1A 2 0.30 1.95 0.07
192 INT327398 Negative_regulation of Regulation of Mmp2 1 0.28 1.25 0.07
193 INT301115 Negative_regulation of Positive_regulation of Mmp2 3 0.38 3.04 0.06
194 INT236876 Negative_regulation of Localization of SRD5A1 1 0.41 0.81 0.06
195 INT206866 Positive_regulation of SFRP1 7 0.51 3.97 0.05
196 INT287913 Positive_regulation of Gene_expression of SFRP1 2 0.25 2.12 0.05
197 INT176573 Positive_regulation of Esr2 2 0.01 1.43 0.04
198 INT292575 Phosphorylation of TNFRSF1A 1 0.39 0.2 0.04
199 INT226885 Regulation of Regulation of Mmp2 1 0.17 0.32 0.03
200 INT235949 Regulation of Positive_regulation of Aqp4 1 0.37 0 0.03
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