GO:0071417

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Name cellular response to organic nitrogen
Categary Process
Go Slim No
Go Link GO:0071417
Unique Molecular Interactions 72
Total Molecular Interactions 123
Total Single Events 616
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular response to organic nitrogen. They are ordered first by their pain relevance and then by number of times they were reported for cellular response to organic nitrogen. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT128860 NR1H4 Negative_regulation of Gene_expression of OPRM1 1 0.15 0.31 0.92
2 INT177269 Binding of CXADR and NR1H4 1 0.04 0 0.58
3 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
4 INT173120 Binding of PPARA and NR1H4 8 0.09 2.79 0.23
5 INT278610 CDCA2 Negative_regulation of NR1H4 1 0.01 0.62 0.13
6 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
7 INT264403 NR1H4 Negative_regulation of IL1R2 1 0.04 0.09 0.12
8 INT177263 Binding of NR1H4 and FAUP1 1 0.00 0 0.09
9 INT177278 Binding of HLA-DRB4 and NR1H4 1 0.02 0 0.08
10 INT279416 NR1H4 Regulation of PPARA 1 0.01 0.13 0.08
11 INT177265 Binding of CYP3A4 and NR1H4 1 0.03 0 0.08
12 INT279421 Binding of NR1H4 and MLXIPL 1 0.00 0.27 0.07
13 INT177255 Binding of SV2A and NR1H4 1 0.04 0 0.07
14 INT182943 Binding of DR1 and NR1H4 3 0.03 0.14 0.06
15 INT113862 Binding of CA2 and NR1H4 1 0.00 0 0.06
16 INT113861 Binding of CA3 and NR1H4 1 0.00 0 0.06
17 INT204074 Tp53 Positive_regulation of Cdkn1b 1 0.00 0.59 0.06
18 INT253377 Lep Negative_regulation of Phosphorylation of Prkaa2 1 0.24 1.24 0.06
19 INT177276 Positive_regulation of Binding of CXADR and NR1H4 1 0.04 0 0.05
20 INT177282 Regulation of Binding of CXADR and NR1H4 1 0.02 0 0.05
21 INT177270 Binding of TNFRSF25 and NR1H4 2 0.02 0.21 0.04
22 INT177272 Binding of ABCB1 and NR1H4 1 0.02 0 0.04
23 INT253413 ATIC Positive_regulation of Gene_expression of Prkaa2 1 0.02 0 0.04
24 INT253417 ATIC Positive_regulation of Prkaa2 1 0.02 0.31 0.04
25 INT253363 Lep Regulation of Prkaa2 1 0.15 0.08 0.04
26 INT256418 PPARA Positive_regulation of NR1H4 1 0.01 1.17 0.04
27 INT253365 Il6 Negative_regulation of Prkaa2 1 0.23 0 0.04
28 INT228591 Adipoq Positive_regulation of Phosphorylation of Prkaa2 1 0.31 0.61 0.04
29 INT253415 ATIC Regulation of Phosphorylation of Prkaa2 1 0.03 0 0.03
30 INT253418 ATIC Regulation of Prkaa2 1 0.02 0 0.03
31 INT264382 NR1H4 Positive_regulation of VDR 1 0.04 0.09 0.03
32 INT264396 NR1H4 Positive_regulation of THRA 1 0.01 0.09 0.03
33 INT253370 Lep Negative_regulation of Prkaa2 1 0.29 0.18 0.03
34 INT182950 Binding of VDR and NR1H4 5 0.03 1.16 0
35 INT182924 Binding of RARA and NR1H4 3 0.02 1.9 0
36 INT290033 Binding of PPARD and NR1H4 1 0.01 0.39 0
37 INT253359 Positive_regulation of Prkaa2 Negative_regulation of Mtor 1 0.26 0.27 0
38 INT315395 Regulation of Binding of IFNA1 and Tp53 1 0.00 0.46 0
39 INT290027 Binding of PPARG and NR1H4 1 0.03 0.39 0
40 INT253368 Positive_regulation of Lep Positive_regulation of Prkaa2 1 0.26 0.19 0
41 INT290029 Binding of INS and NR1H4 1 0.01 0.47 0
42 INT315397 Binding of IFNA1 and Tp53 1 0.00 0.43 0
43 INT286044 Wwox Positive_regulation of Tp53 1 0.05 0.63 0
44 INT337708 Naf1 Regulation of Gene_expression of Tp53 1 0.09 0.22 0
45 INT183014 Binding of NR1H4 and Dre 1 0.00 0.06 0
46 INT182955 Positive_regulation of Binding of VDR and NR1H4 1 0.03 0 0
47 INT302303 Binding of NR1H4 and Rdh5 1 0.02 0.11 0
48 INT253382 Il6 Positive_regulation of Prkaa2 1 0.42 0.19 0
49 INT253361 Il6 Negative_regulation of Phosphorylation of Prkaa2 1 0.26 0.16 0
50 INT330226 Positive_regulation of Prkaa2 Positive_regulation of Trib3 1 0.00 0.07 0
51 INT330956 Binding of TEP1 and NR1H4 1 0.00 1.07 0
52 INT325375 Binding of Tp53 and Positive_regulation of Positive_regulation of PARP1 1 0.05 0.59 0
53 INT253369 Prkaa2 Negative_regulation of Mtor 1 0.24 0.27 0
54 INT330225 Binding of Tmprss5 and Positive_regulation of Positive_regulation of Prkaa2 1 0.01 0.18 0
55 INT351977 Binding of Tp53 and Trib3 1 0.01 0.79 0
56 INT330224 Tmprss5 Positive_regulation of Prkaa2 1 0.01 0 0
57 INT253379 Lep Positive_regulation of Prkaa2 1 0.39 0.19 0
58 INT253373 Binding of Mtor and Prkaa2 1 0.20 0.26 0
59 INT234439 Binding of NR1H4 and HCC 1 0.06 0.82 0
60 INT300307 Binding of Tp53 and Sirt1 1 0.24 0.98 0
61 INT253372 Prkaa2 Regulation of Mtor 1 0.13 0.09 0
62 INT351976 Binding of Tp53 and Stk11 1 0.13 2.3 0
63 INT286029 Binding of Tp53 and Atf2 1 0.03 0.33 0
64 INT253381 Il6 Regulation of Prkaa2 1 0.16 0 0
65 INT294428 PSEN2 Regulation of Gene_expression of Tp53 1 0.49 0.86 0
66 INT278605 CDCA2 Positive_regulation of NR1H4 1 0.01 0.36 0
67 INT294429 PSEN2 Negative_regulation of Tp53 1 0.46 1.03 0
68 INT182930 Binding of TNFRSF10B and NR1H4 1 0.02 0 0
69 INT135128 Binding of NR1I2 and NR1H4 1 0.09 0.57 0
70 INT182963 Binding of NR1H4 and KCNIP3 1 0.03 0.45 0
71 INT265547 Positive_regulation of Tp53 Positive_regulation of Gene_expression of Kras 1 0.01 0.93 0
72 INT330223 Binding of Tmprss5 and Positive_regulation of Prkaa2 1 0.01 0.18 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular response to organic nitrogen. They are ordered first by their pain relevance and then by number of times they were reported in cellular response to organic nitrogen. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
2 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
3 INT132575 Binding of NR1H4 57 0.20 22.06 2.82
4 INT114953 Gene_expression of NR1H4 23 0.29 16.58 2.02
5 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
6 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
7 INT135132 Positive_regulation of NR1H4 17 0.30 8.63 1.38
8 INT145221 Binding of Tp53 10 0.37 8.59 1.37
9 INT114961 Positive_regulation of Gene_expression of NR1H4 6 0.16 3.55 1.23
10 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
11 INT71747 Positive_regulation of Prkaa2 19 0.46 8.76 0.98
12 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
13 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
14 INT228570 Phosphorylation of Prkaa2 24 0.61 7.9 0.5
15 INT286035 Negative_regulation of Gene_expression of Tp53 5 0.32 6.2 0.49
16 INT234463 Phosphorylation of NR1H4 23 0.34 14.56 0.39
17 INT139976 Regulation of Tp53 7 0.44 6.49 0.39
18 INT145220 Negative_regulation of Binding of Tp53 1 0.20 0.75 0.36
19 INT234456 Negative_regulation of Gene_expression of NR1H4 2 0.18 1.05 0.32
20 INT71752 Negative_regulation of Prkaa2 17 0.39 2.81 0.3
21 INT71750 Regulation of Prkaa2 12 0.41 2.98 0.29
22 INT187504 Gene_expression of Prkaa2 5 0.65 1.3 0.22
23 INT253395 Negative_regulation of Phosphorylation of Prkaa2 9 0.39 1.35 0.2
24 INT300284 Regulation of Phosphorylation of Tp53 1 0.16 1.51 0.17
25 INT234469 Negative_regulation of Phosphorylation of NR1H4 2 0.14 1.25 0.16
26 INT253401 Positive_regulation of Positive_regulation of Prkaa2 2 0.33 1.39 0.15
27 INT168244 Regulation of Transcription of Tp53 1 0.33 0.57 0.13
28 INT234464 Negative_regulation of NR1H4 6 0.19 3.54 0.12
29 INT187495 Positive_regulation of Gene_expression of Prkaa2 1 0.49 0.09 0.11
30 INT297456 Protein_catabolism of Tp53 1 0.11 0.72 0.1
31 INT111139 Localization of Tp53 4 0.45 2.4 0.09
32 INT253404 Positive_regulation of Phosphorylation of Prkaa2 3 0.29 1.23 0.09
33 INT234468 Protein_catabolism of NR1H4 2 0.32 0.87 0.09
34 INT177318 Negative_regulation of Binding of NR1H4 5 0.14 3.39 0.08
35 INT253390 Negative_regulation of Positive_regulation of Prkaa2 4 0.28 0.76 0.08
36 INT234477 Localization of NR1H4 3 0.24 2.23 0.07
37 INT253387 Negative_regulation of Regulation of Prkaa2 1 0.28 0.08 0.05
38 INT178927 Regulation of Gene_expression of Tp53 6 0.26 2.23 0
39 INT177301 Positive_regulation of Binding of NR1H4 3 0.29 0.45 0
40 INT253402 Binding of Prkaa2 2 0.24 0.43 0
41 INT214913 Positive_regulation of Positive_regulation of Tp53 2 0.08 2.47 0
42 INT234451 Positive_regulation of Phosphorylation of NR1H4 1 0.22 5.15 0
43 INT204059 Positive_regulation of Phosphorylation of Tp53 1 0.07 0.76 0
44 INT253408 Positive_regulation of Negative_regulation of Prkaa2 1 0.33 0.44 0
45 INT330234 Localization of Prkaa2 1 0.21 0 0
46 INT234475 Transcription of NR1H4 1 0.17 1.62 0
47 INT253394 Negative_regulation of Negative_regulation of Prkaa2 1 0.28 0.33 0
48 INT179957 Positive_regulation of Binding of Tp53 1 0.08 0.48 0
49 INT234470 Positive_regulation of Protein_catabolism of NR1H4 1 0.22 0.93 0
50 INT264439 Regulation of Binding of NR1H4 1 0.19 0 0
51 INT223765 Negative_regulation of Positive_regulation of Tp53 1 0.07 1.69 0
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