GO:0071456

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Name cellular response to hypoxia
Categary Process
Go Slim No
Go Link GO:0071456
Unique Molecular Interactions 1881
Total Molecular Interactions 2683
Total Single Events 21753
Pain Genes Associated 66

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular response to hypoxia. They are ordered first by their pain relevance and then by number of times they were reported for cellular response to hypoxia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
3 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
4 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
5 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
6 INT202965 Binding of STC2 and BAG3 1 0.02 7.86 2.96
7 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81
8 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
9 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
10 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
11 INT147659 Prkce Positive_regulation of TRPV1 1 0.04 1.42 2.43
12 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
13 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
14 INT202963 Binding of STC2 and CPP 1 0.02 5.16 2.04
15 INT135582 Prok2 Positive_regulation of Localization of Prkce 1 0.06 1.02 1.87
16 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83
17 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
18 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
19 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
20 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
21 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
22 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
23 INT324926 Ptpro Positive_regulation of Bdkrb2 1 0.01 2.25 1.5
24 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
25 INT202958 Binding of STC2 and MCRS1 1 0.01 3.48 1.44
26 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
27 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
28 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
29 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
30 INT48881 TWIST1 Positive_regulation of Localization of Abat 1 0.02 0.44 1.29
31 INT112961 NGF Positive_regulation of ICAM1 1 0.40 0.96 1.28
32 INT177232 ICAM1 Regulation of Gene_expression of Vcam1 1 0.03 5.52 1.28
33 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25
34 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
35 INT151657 Vcam1 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
36 INT151658 F3 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
37 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
38 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
39 INT334129 Acsm3 Positive_regulation of Gene_expression of Icam1 1 0.22 2.89 1.22
40 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
41 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
42 INT150835 Gper Positive_regulation of Localization of Prkce 1 0.15 0.62 1.18
43 INT111221 MMEL1 Negative_regulation of HMOX1 1 0.01 1 1.16
44 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
45 INT189017 Binding of Pax3 and Lmna 1 0.14 0.42 1.16
46 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
47 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
48 INT147660 Positive_regulation of Prkce Positive_regulation of TRPV1 1 0.04 0.69 1.12
49 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
50 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
51 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
52 INT229913 Positive_regulation of Ntsr1 Positive_regulation of Gene_expression of Egr1 1 0.12 1.33 1.11
53 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
54 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
55 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07
56 INT96905 Plxna3 Regulation of Regulation of Prkce 1 0.18 0.71 1.07
57 INT139230 Icam1 Negative_regulation of Cmklr1 1 0.19 1.13 1.07
58 INT139227 Icam1 Negative_regulation of Timp1 1 0.37 1.13 1.06
59 INT139225 Calca Negative_regulation of Icam1 1 0.44 1.13 1.06
60 INT139226 Icam1 Negative_regulation of Calca 1 0.44 1.12 1.05
61 INT151218 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.26 1.03
62 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02
63 INT121743 Negative_regulation of Src Negative_regulation of Ephb1 1 0.27 0 1.02
64 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
65 INT61860 Akr1d1 Regulation of Egr1 1 0.01 0 0.96
66 INT121744 Src Positive_regulation of Positive_regulation of Ephb1 1 0.35 0 0.96
67 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
68 INT61861 Akr1d1 Regulation of Positive_regulation of Egr1 1 0.01 0 0.96
69 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96
70 INT275097 Twist1 Regulation of Ltp 1 0.01 0.37 0.96
71 INT142709 Binding of TWIST1 and CEBPZ 2 0.17 1.16 0.95
72 INT161231 Positive_regulation of Htr1a Positive_regulation of Gene_expression of VEGFA 1 0.67 0.16 0.95
73 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
74 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
75 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
76 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
77 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
78 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
79 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
80 INT61859 Akr1d1 Positive_regulation of Egr1 1 0.01 0 0.92
81 INT61862 Slc3a1 Positive_regulation of Egr1 1 0.05 0 0.92
82 INT289461 IRF6 Positive_regulation of ICAM1 1 0.08 0.61 0.91
83 INT109842 Prkce Positive_regulation of Localization of Trpv1 1 0.13 1.31 0.91
84 INT317541 Oprd1 Negative_regulation of Akt1 1 0.06 0 0.91
85 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
86 INT249012 Binding of Akt1 and Gabrg1 1 0.01 0 0.9
87 INT132226 Binding of Akt1 and Pik3cg 1 0.30 0.49 0.9
88 INT40636 Mif Negative_regulation of Pomc 1 0.25 0.07 0.9
89 INT101259 Gata6 Negative_regulation of Gene_expression of ALOX15 1 0.42 0.67 0.89
90 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
91 INT277832 Binding of TNFRSF1B and NPEPPS 1 0.01 1.1 0.88
92 INT277831 Binding of TNFRSF1A and NPEPPS 1 0.01 1.1 0.87
93 INT199109 Binding of Akt1 and Arhgdia 1 0.02 2.73 0.87
94 INT101258 Gene_expression of Gata6 Negative_regulation of Positive_regulation of ALOX15 1 0.42 0.65 0.87
95 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87
96 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
97 INT285660 Cnrip1 Negative_regulation of Kcnk3 1 0.00 0.23 0.85
98 INT285656 Cnrip1 Negative_regulation of Kcnk3 1 0.00 0.23 0.85
99 INT124427 NPEPPS Positive_regulation of Protein_catabolism of COL7A1 1 0.00 0.56 0.84
100 INT116108 VEGFA Positive_regulation of SEC23IP 1 0.10 0.3 0.83
101 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
102 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
103 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
104 INT317556 Phosphorylation of Gopc Positive_regulation of Akt1 1 0.10 0.08 0.82
105 INT317514 Akt1 Regulation of Localization of Oprm1 1 0.21 0.07 0.82
106 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
107 INT108331 EGF Positive_regulation of Phosphorylation of BAD 1 0.49 6.72 0.8
108 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
109 INT150643 Binding of Bdkrb2 and Trpa1 1 0.36 0.55 0.78
110 INT182814 Binding of ICAM1 and PECAM1 2 0.02 3.32 0.77
111 INT111888 Akt1 Regulation of Regulation of Oprm1 1 0.04 0 0.77
112 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
113 INT140790 Positive_regulation of Ptger3 Negative_regulation of Negative_regulation of Bdkrb2 1 0.00 0.07 0.76
114 INT81299 Ifng Positive_regulation of Gene_expression of Hmox1 1 0.52 0.75 0.76
115 INT152867 HTR1A Negative_regulation of Localization of S100b 1 0.46 0 0.75
116 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74
117 INT335592 Ltp Positive_regulation of Positive_regulation of Akt1 1 0.01 0.19 0.74
118 INT106527 Akt1 Positive_regulation of Jun 1 0.05 0.53 0.74
119 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73
120 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73
121 INT243626 Twist1 Regulation of Hand1 1 0.15 1.55 0.72
122 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
123 INT123494 Binding of Egr1 and Ccr5 1 0.04 0.94 0.71
124 INT120018 VEGFA Positive_regulation of CCL3 1 0.01 1 0.7
125 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
126 INT40703 Mif Negative_regulation of Negative_regulation of POMC 1 0.24 0.49 0.7
127 INT120036 VEGFA Positive_regulation of Prap1 1 0.00 1 0.7
128 INT148454 Gene_expression of Inhbe Positive_regulation of Prkce 1 0.08 0.67 0.69
129 INT253994 Cyp3a23/3a1 Positive_regulation of Localization of Mif 1 0.09 0.96 0.69
130 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
131 INT99743 Olr1742 Regulation of Gene_expression of Hmox1 1 0.00 0 0.68
132 INT167355 VEGFA Regulation of RYBP 1 0.01 0.53 0.68
133 INT168295 PROC Regulation of Gene_expression of VEGFA 2 0.00 1.6 0.67
134 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
135 INT92025 Egr1 Positive_regulation of Jun 1 0.15 0.61 0.67
136 INT92026 Egr1 Positive_regulation of Fos 1 0.50 0.61 0.67
137 INT70998 IL1B Regulation of Gene_expression of Icam1 1 0.44 0.95 0.67
138 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
139 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
140 INT335054 LPL Positive_regulation of Localization of VLDLR 1 0.04 1.48 0.67
141 INT154766 Nox1 Positive_regulation of Localization of Prkce 1 0.47 0.45 0.66
142 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66
143 INT334133 Acsm3 Positive_regulation of Icam1 1 0.23 1.61 0.66
144 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
145 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65
146 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
147 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
148 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
149 INT243639 Twist1 Negative_regulation of Gene_expression of Il2 1 0.24 1.28 0.65
150 INT66603 TFF2 Positive_regulation of Gene_expression of ICAM1 1 0.02 0 0.64
151 INT112513 Binding of Prkaca and Prkce 1 0.04 0.4 0.64
152 INT99744 Calca Positive_regulation of Positive_regulation of Hmox1 1 0.48 0 0.64
153 INT112516 Binding of Prkce and Trib3 1 0.01 0.4 0.64
154 INT134047 Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
155 INT134044 Positive_regulation of Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
156 INT346141 ADM Positive_regulation of Gene_expression of ICAM1 1 0.19 1.75 0.63
157 INT66601 WDR87 Positive_regulation of Gene_expression of ICAM1 1 0.00 0 0.63
158 INT66604 SARDH Positive_regulation of Gene_expression of ICAM1 1 0.01 0 0.63
159 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63
160 INT176475 IL1B Positive_regulation of Gene_expression of ICAM1 1 0.02 0.56 0.62
161 INT121460 KNG1 Positive_regulation of Bdkrb2 1 0.08 0.44 0.62
162 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
163 INT121459 Bdkrb2 Positive_regulation of KNG1 1 0.09 0.44 0.62
164 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61
165 INT200808 Binding of Akt1 and Insrr 2 0.00 0.98 0.61
166 INT224731 Binding of VEGFA and Cia1 1 0.01 0.91 0.61
167 INT224733 Negative_regulation of Binding of VEGFA and Cia1 1 0.01 0.91 0.61
168 INT98629 VEGFA Positive_regulation of Gene_expression of EGR1 1 0.52 0.42 0.61
169 INT98628 VEGFA Positive_regulation of Transcription of EGR1 1 0.52 0.42 0.61
170 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
171 INT182815 Binding of CD63 and ICAM1 1 0.00 1.63 0.61
172 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61
173 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6
174 INT145661 Ptger2 Positive_regulation of Gene_expression of VEGFA 4 0.27 2.73 0.6
175 INT299286 VEGFA Positive_regulation of PI3 1 0.16 0.46 0.6
176 INT121453 Bdkrb2 Positive_regulation of Trpv1 1 0.28 0.42 0.6
177 INT164990 Mif Positive_regulation of Gene_expression of Grina 1 0.24 0.53 0.6
178 INT168416 MIR146A Regulation of Irak1 1 0.24 0.99 0.59
179 INT248994 Binding of Akt1 and Ptar1 1 0.00 0 0.58
180 INT102864 Prkaca Regulation of Twist1 1 0.48 0.05 0.58
181 INT202970 Binding of STC2 and CAP1 1 0.00 1.25 0.58
182 INT342624 VEGFA Negative_regulation of Mmp2 1 0.09 1.54 0.58
183 INT100225 Binding of Egf and Src 1 0.01 0.67 0.58
184 INT327339 Gtf3a Positive_regulation of VEGFA 1 0.00 2.34 0.58
185 INT277828 Negative_regulation of Binding of ICAM1 and ITGAL 2 0.22 1.27 0.57
186 INT202961 MCRS1 Negative_regulation of STC2 1 0.00 1.63 0.57
187 INT304326 Ptger1 Positive_regulation of Gene_expression of VEGFA 1 0.19 1.37 0.57
188 INT342621 VEGFA Negative_regulation of Timp2 1 0.09 1.53 0.57
189 INT66600 TFF2 Regulation of Positive_regulation of ICAM1 1 0.01 0 0.56
190 INT323176 PRKCA Positive_regulation of Phosphorylation of Akt1 1 0.02 0 0.56
191 INT81303 Tlr4 Positive_regulation of Gene_expression of Hmox1 1 0.03 0.55 0.56
192 INT302832 Tnfsf10 Positive_regulation of Akt1 1 0.04 1.63 0.56
193 INT261478 Positive_regulation of Ephb1 Regulation of Gene_expression of Egr1 1 0.10 0.23 0.55
194 INT126641 Binding of KNG1 and Bdkrb2 1 0.11 0.42 0.55
195 INT144129 Prkce Positive_regulation of Phosphorylation of Gja1 1 0.42 0.48 0.55
196 INT133049 TNF Positive_regulation of ICAM1 4 0.47 2.49 0.54
197 INT114064 Agtr2 Positive_regulation of Phosphorylation of Akt1 1 0.24 0.41 0.54
198 INT282284 Cpox Positive_regulation of Akt1 1 0.02 0.47 0.54
199 INT282282 Ptger2 Positive_regulation of Akt1 1 0.03 0.47 0.54
200 INT162994 Binding of Akt1 and Trib3 1 0.04 0.09 0.54

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular response to hypoxia. They are ordered first by their pain relevance and then by number of times they were reported in cellular response to hypoxia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
2 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6
3 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71
4 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
5 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
6 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13
7 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
8 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
9 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
10 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
11 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
12 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28
13 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
14 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55
15 INT5862 Positive_regulation of Egr1 82 0.70 30.4 33.96
16 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
17 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
18 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18
19 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
20 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
21 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68
22 INT116737 Localization of Mif 63 0.81 52.97 28.11
23 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
24 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34
25 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93
26 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
27 INT48235 Negative_regulation of NPEPPS 72 0.46 44.54 25.03
28 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
29 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
30 INT48407 Positive_regulation of Gene_expression of Icam1 61 0.70 57.91 21.54
31 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
32 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61
33 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
34 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
35 INT62826 Negative_regulation of Gene_expression of ICAM1 75 0.58 46.39 17.72
36 INT76406 Gene_expression of Hmox1 140 0.78 85.86 17.15
37 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
38 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
39 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
40 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37
41 INT5333 Gene_expression of NPEPPS 45 0.65 26.34 15.25
42 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89
43 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66
44 INT37803 Positive_regulation of Bdkrb2 18 0.68 14.21 13.99
45 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
46 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
47 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8
48 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39
49 INT26534 Regulation of Akt1 34 0.61 14.47 11.86
50 INT114674 Gene_expression of Mdm2 15 0.78 3.51 11.85
51 INT72949 Binding of Mif 31 0.46 23.12 11.65
52 INT65713 Localization of ICAM1 42 0.81 39.55 11.49
53 INT88223 Gene_expression of Bdkrb2 17 0.69 13.94 11.44
54 INT10874 Negative_regulation of Twist1 89 0.50 36.84 11.32
55 INT88650 Negative_regulation of Prkce 13 0.57 11.93 11.16
56 INT15305 Positive_regulation of Mtor 51 0.67 8.28 11
57 INT56448 Regulation of ICAM1 52 0.60 55.1 10.96
58 INT111223 Positive_regulation of HMOX1 47 0.70 39.14 10.92
59 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4
60 INT91948 Positive_regulation of Prkce 16 0.64 11.36 10.32
61 INT20166 Negative_regulation of Mtor 32 0.56 10.64 10.25
62 INT56450 Negative_regulation of Gene_expression of Icam1 33 0.52 27.21 10.15
63 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
64 INT80549 Binding of ICAM1 53 0.47 42.76 9.72
65 INT75137 Regulation of Akt1 74 0.48 37.89 9.7
66 INT63341 Negative_regulation of ICAM1 42 0.59 30.45 9.5
67 INT72148 Positive_regulation of Prkce 17 0.68 5.06 9.44
68 INT15307 Regulation of Mtor 27 0.48 4.7 9.34
69 INT130497 Gene_expression of Cbs 5 0.77 16.93 9.34
70 INT63338 Regulation of Gene_expression of ICAM1 42 0.62 28.26 9.06
71 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01
72 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98
73 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97
74 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69
75 INT43820 Positive_regulation of Twist1 75 0.59 42.15 8.47
76 INT9573 Regulation of Bdkrb2 9 0.43 6.04 8.41
77 INT82450 Negative_regulation of Hmox1 33 0.55 19.07 8.12
78 INT62944 Regulation of Icam1 33 0.47 23.52 7.94
79 INT114675 Positive_regulation of Gene_expression of Mdm2 1 0.70 1.98 7.9
80 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83
81 INT48404 Regulation of Gene_expression of Icam1 21 0.62 15.1 7.81
82 INT6055 Transcription of Egr1 47 0.69 3.61 7.68
83 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
84 INT103925 Negative_regulation of Positive_regulation of Akt1 32 0.58 15.19 7.39
85 INT81293 Positive_regulation of Gene_expression of Hmox1 53 0.70 41.54 7.25
86 INT6057 Negative_regulation of Gene_expression of Egr1 17 0.57 4.17 7.17
87 INT126748 Positive_regulation of Positive_regulation of Akt1 26 0.55 11.15 7.08
88 INT47707 Negative_regulation of Egr1 9 0.41 0.17 7.03
89 INT110104 Localization of Prkce 17 0.79 3.75 6.92
90 INT117299 Localization of S100b 19 0.78 1.58 6.8
91 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63
92 INT517 Regulation of Mif 16 0.62 5.43 6.55
93 INT65295 Negative_regulation of Bdkrb2 9 0.37 6.36 6.49
94 INT5860 Regulation of Gene_expression of Egr1 20 0.62 3.02 6.38
95 INT23465 Gene_expression of S100b 31 0.76 15.09 6.2
96 INT117721 Positive_regulation of Gene_expression of Akt1 22 0.69 6.26 6.08
97 INT516 Negative_regulation of Mif 13 0.59 6.69 6.08
98 INT135170 Positive_regulation of Hif1a 86 0.67 99.4 6.07
99 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06
100 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
101 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88
102 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78
103 INT82451 Negative_regulation of HMOX1 18 0.51 13.29 5.74
104 INT71727 Negative_regulation of Icam1 25 0.45 17.76 5.73
105 INT101497 Phosphorylation of Prkce 9 0.81 2.55 5.59
106 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
107 INT65712 Positive_regulation of Localization of ICAM1 14 0.70 16.72 5.5
108 INT91946 Regulation of Prkce 6 0.44 4.13 5.46
109 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45
110 INT135172 Gene_expression of Hif1a 56 0.76 46.49 5.44
111 INT136664 Positive_regulation of Gene_expression of Twist1 49 0.69 25.91 5.41
112 INT100222 Binding of Src 9 0.26 5.41 5.37
113 INT94028 Regulation of Twist1 37 0.44 22.41 5.33
114 INT156134 Regulation of Gene_expression of Aqp1 5 0.59 7.2 5.3
115 INT60585 Regulation of TP53 59 0.59 54.55 5.21
116 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19
117 INT47704 Regulation of Egr1 17 0.60 2.43 5.18
118 INT106667 Gene_expression of NDRG1 18 0.70 9.96 5.14
119 INT47706 Negative_regulation of Positive_regulation of Egr1 9 0.41 6.11 5.1
120 INT23611 Gene_expression of Mtor 23 0.66 3.57 5.02
121 INT89844 Positive_regulation of Phosphorylation of Src 10 0.43 4.71 4.95
122 INT174339 Positive_regulation of Localization of Mif 7 0.61 8.27 4.95
123 INT109838 Phosphorylation of Prkce 6 0.67 5.26 4.95
124 INT85328 Negative_regulation of Aqp1 5 0.54 6.02 4.94
125 INT100220 Negative_regulation of Src 13 0.41 6.37 4.93
126 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9
127 INT116527 Positive_regulation of Gene_expression of HMOX1 29 0.70 25.79 4.87
128 INT60066 Positive_regulation of NPEPPS 17 0.22 11.99 4.83
129 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79
130 INT51944 Positive_regulation of Transcription of Egr1 12 0.49 1.96 4.72
131 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
132 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
133 INT134657 Localization of Akt1 37 0.68 11.58 4.62
134 INT60758 Gene_expression of Prkce 8 0.20 4.12 4.59
135 INT79902 Gene_expression of AQP1 33 0.78 24.72 4.55
136 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
137 INT122569 Negative_regulation of Gene_expression of Akt1 34 0.54 17.15 4.44
138 INT4283 Positive_regulation of Cbs 10 0.46 6.85 4.44
139 INT5332 Negative_regulation of Gene_expression of NPEPPS 11 0.04 7.79 4.29
140 INT112704 Positive_regulation of Hif1a 25 0.67 21.49 4.23
141 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22
142 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17
143 INT75136 Binding of Akt1 27 0.27 8.81 4.15
144 INT60067 Localization of NPEPPS 9 0.26 3.36 4.15
145 INT33229 Gene_expression of Bad 9 0.70 6.95 4.15
146 INT21681 Positive_regulation of CD34 54 0.66 33.95 4.14
147 INT139898 Negative_regulation of Positive_regulation of Akt1 15 0.42 4.66 4.06
148 INT202978 Gene_expression of STC2 11 0.50 13.46 4.06
149 INT73114 Gene_expression of Kcnk3 32 0.77 1.57 4.03
150 INT118835 Positive_regulation of Vegfa 18 0.59 11.2 3.91
151 INT88221 Positive_regulation of Gene_expression of Bdkrb2 5 0.36 3.35 3.91
152 INT97096 Regulation of Hmox1 18 0.61 6.42 3.9
153 INT280193 Positive_regulation of Gene_expression of Cbs 1 0.69 6.59 3.81
154 INT116738 Positive_regulation of Gene_expression of Mif 14 0.68 10.99 3.8
155 INT60415 Regulation of NPEPPS 13 0.27 5.81 3.78
156 INT202976 Positive_regulation of STC2 1 0.04 9.73 3.78
157 INT123502 Binding of Egr1 11 0.35 6.7 3.77
158 INT70996 Positive_regulation of Positive_regulation of Icam1 8 0.60 6.02 3.74
159 INT85326 Positive_regulation of Aqp1 7 0.65 5.9 3.71
160 INT132223 Negative_regulation of Negative_regulation of Akt1 6 0.42 2.75 3.66
161 INT136692 Localization of Akt1 12 0.78 2.14 3.65
162 INT122327 Regulation of Src 6 0.59 0.59 3.6
163 INT104570 Localization of Aqp1 8 0.77 5.83 3.51
164 INT109840 Localization of Prkce 5 0.74 3.01 3.45
165 INT141148 Gene_expression of BMP7 24 0.71 14.34 3.44
166 INT64766 Gene_expression of TWIST1 41 0.76 37.89 3.4
167 INT202983 Regulation of STC2 1 0.03 11.98 3.33
168 INT135773 Negative_regulation of Gene_expression of HMOX1 31 0.53 28.31 3.32
169 INT202977 Binding of STC2 1 0.02 8.53 3.31
170 INT67379 Positive_regulation of Cd34 38 0.58 26.18 3.28
171 INT157687 Regulation of Gene_expression of Akt1 9 0.62 4.96 3.27
172 INT99687 Negative_regulation of Transcription of VEGFA 17 0.43 10.3 3.25
173 INT111547 Negative_regulation of Phosphorylation of VEGFA 13 0.42 5.08 3.22
174 INT88220 Transcription of Bdkrb2 6 0.65 3.08 3.21
175 INT110100 Negative_regulation of Prkce 5 0.57 0.68 3.16
176 INT70994 Negative_regulation of Positive_regulation of Icam1 8 0.51 3.49 3.12
177 INT101034 Protein_catabolism of NPEPPS 8 0.65 2.08 3.12
178 INT82168 Positive_regulation of S100b 20 0.68 9.72 3.08
179 INT117720 Negative_regulation of Gene_expression of Akt1 11 0.37 2.33 3.08
180 INT112365 Regulation of HIF1A 27 0.60 21.24 3.05
181 INT109496 Gene_expression of KCNK3 9 0.78 0.59 3.02
182 INT137609 Localization of Vegfa 22 0.78 14.67 3.01
183 INT8103 Binding of TP53 46 0.44 40.2 2.96
184 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88
185 INT116540 Binding of Twist1 35 0.48 16.32 2.85
186 INT41721 Negative_regulation of MTOR 40 0.58 32.49 2.83
187 INT117715 Regulation of Phosphorylation of Akt1 15 0.51 3.23 2.78
188 INT126636 Binding of Bdkrb2 3 0.33 2.18 2.78
189 INT228678 Phosphorylation of Mtor 15 0.78 3.18 2.76
190 INT74216 Binding of Icam1 16 0.48 10.11 2.69
191 INT134756 Positive_regulation of Gene_expression of Hif1a 8 0.50 11.14 2.68
192 INT101246 Gene_expression of Gata6 6 0.68 3.03 2.68
193 INT43719 Positive_regulation of Vegfa 21 0.69 5.15 2.64
194 INT128184 Positive_regulation of Positive_regulation of Prkce 4 0.41 1.3 2.64
195 INT214355 Binding of Akt1 13 0.36 3.72 2.59
196 INT152865 Positive_regulation of Localization of S100b 3 0.68 0 2.53
197 INT29983 Localization of Bad 5 0.28 4.44 2.52
198 INT88222 Positive_regulation of Transcription of Bdkrb2 3 0.47 1.32 2.51
199 INT106668 Positive_regulation of Gene_expression of NDRG1 3 0.10 1.93 2.49
200 INT81291 Regulation of Gene_expression of Hmox1 11 0.60 8.78 2.46
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