GO:0071506

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Name cellular response to mycophenolic acid
Categary Process
Go Slim No
Go Link GO:0071506
Unique Molecular Interactions 118
Total Molecular Interactions 142
Total Single Events 1383
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular response to mycophenolic acid. They are ordered first by their pain relevance and then by number of times they were reported for cellular response to mycophenolic acid. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
2 INT229913 Positive_regulation of Ntsr1 Positive_regulation of Gene_expression of Egr1 1 0.12 1.33 1.11
3 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02
4 INT61860 Akr1d1 Regulation of Egr1 1 0.01 0 0.96
5 INT61861 Akr1d1 Regulation of Positive_regulation of Egr1 1 0.01 0 0.96
6 INT61859 Akr1d1 Positive_regulation of Egr1 1 0.01 0 0.92
7 INT61862 Slc3a1 Positive_regulation of Egr1 1 0.05 0 0.92
8 INT123494 Binding of Egr1 and Ccr5 1 0.04 0.94 0.71
9 INT92025 Egr1 Positive_regulation of Jun 1 0.15 0.61 0.67
10 INT92026 Egr1 Positive_regulation of Fos 1 0.50 0.61 0.67
11 INT312106 EGR1 Regulation of Gene_expression of PTGES 1 0.31 1.06 0.64
12 INT98629 VEGFA Positive_regulation of Gene_expression of EGR1 1 0.52 0.42 0.61
13 INT98628 VEGFA Positive_regulation of Transcription of EGR1 1 0.52 0.42 0.61
14 INT115146 MAPK1 Positive_regulation of EGR1 3 0.13 2.43 0.57
15 INT261478 Positive_regulation of Ephb1 Regulation of Gene_expression of Egr1 1 0.10 0.23 0.55
16 INT130930 Egr1 Negative_regulation of Positive_regulation of Thbs1 1 0.58 0.64 0.38
17 INT123495 Negative_regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
18 INT123493 Regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
19 INT90722 Nr4a1 Positive_regulation of Egr1 1 0.20 0.48 0.35
20 INT312124 EGR1 Regulation of Binding of PTGES 1 0.31 0.41 0.35
21 INT90723 Nr4a2 Positive_regulation of Egr1 1 0.22 0.49 0.35
22 INT90724 Egr3 Positive_regulation of Egr1 1 0.33 0.48 0.35
23 INT144966 MAPK1 Positive_regulation of Localization of EGR1 1 0.08 0.83 0.35
24 INT126097 Ddc Positive_regulation of Egr1 1 0.08 0 0.32
25 INT225021 PDGFB Positive_regulation of Ccl21 1 0.10 0.07 0.3
26 INT225026 PDGFB Positive_regulation of Gene_expression of Ccl21 1 0.10 0.07 0.3
27 INT202313 Gene_expression of PDGFB Positive_regulation of Positive_regulation of Pdgfrb 1 0.14 1 0.29
28 INT74334 Penk Regulation of Transcription of Egr1 1 0.40 0.25 0.29
29 INT202314 Gene_expression of PDGFB Positive_regulation of Phosphorylation of Pdgfrb 1 0.14 1 0.29
30 INT74336 Crh Regulation of Transcription of Egr1 1 0.49 0.24 0.28
31 INT147356 Egr1 Positive_regulation of Gene_expression of Btg1 1 0.14 1.56 0.28
32 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28
33 INT147358 Egr1 Positive_regulation of Gene_expression of Gdf15 1 0.14 1.56 0.28
34 INT58182 Fos Regulation of Egr1 1 0.49 0.09 0.27
35 INT147359 Positive_regulation of Pik3cd Positive_regulation of Egr1 1 0.09 1.51 0.27
36 INT216128 EGR1 Regulation of TP53 1 0.11 0.21 0.27
37 INT130931 Sis Negative_regulation of Egr1 1 0.01 0.52 0.27
38 INT58176 Junb Regulation of Egr1 1 0.46 0.09 0.27
39 INT355734 Pdgfb Regulation of Bdnf 1 0.22 1.5 0.27
40 INT147360 Pik3cd Positive_regulation of Egr1 1 0.12 1.51 0.27
41 INT125521 EGR1 Regulation of GDF15 1 0.13 0.47 0.26
42 INT98631 Negative_regulation of VEGFA Positive_regulation of EGR1 1 0.44 0.18 0.24
43 INT130060 PPARG Positive_regulation of Positive_regulation of Egr1 1 0.22 0.46 0.24
44 INT98630 VEGFA Positive_regulation of EGR1 1 0.52 0.18 0.24
45 INT144967 MAPK1 Positive_regulation of Positive_regulation of EGR1 1 0.08 0.63 0.24
46 INT184162 Egr1 Positive_regulation of Transcription of Ptges2 1 0.08 0.42 0.22
47 INT184160 Binding of Egr1 and Ptges2 1 0.07 0.4 0.22
48 INT271853 Ngf Positive_regulation of Gene_expression of Egr1 1 0.53 1.36 0.21
49 INT259817 Ltp Positive_regulation of Egr1 1 0.03 0.28 0.2
50 INT259812 Gtf3a Regulation of Egr1 1 0.01 0.58 0.19
51 INT184159 Egr1 Positive_regulation of Ptges2 1 0.07 0.34 0.19
52 INT58178 Gtf3a Positive_regulation of Egr1 1 0.07 0.09 0.19
53 INT184161 Negative_regulation of Egr1 Positive_regulation of Ptges2 1 0.07 0.34 0.19
54 INT259814 Binding of Arc and Egr1 1 0.34 0.55 0.19
55 INT259813 Binding of Egr1 and Arc 1 0.32 0.55 0.19
56 INT149096 PITX2 Positive_regulation of Gene_expression of Egr1 1 0.01 1.23 0.19
57 INT58181 Gtf3a Positive_regulation of Gene_expression of Egr1 1 0.07 0.1 0.19
58 INT355733 Pdgfb Regulation of Transcription of Bdnf 1 0.10 0.86 0.19
59 INT312090 EGR1 Regulation of Positive_regulation of PTGES 1 0.42 0.21 0.18
60 INT317895 Fos Regulation of Transcription of Egr1 1 0.41 1.03 0.17
61 INT317897 Egr1 Regulation of Transcription of Fosb 1 0.34 1.08 0.17
62 INT317892 Egr1 Regulation of Transcription of Fos 1 0.41 1.03 0.17
63 INT355732 Pdgfb Negative_regulation of Bdnf 1 0.13 0.87 0.17
64 INT312109 ELANE Positive_regulation of EGR1 1 0.15 0.23 0.16
65 INT312100 ELANE Positive_regulation of Binding of EGR1 1 0.16 0.23 0.16
66 INT202312 PDGFB Positive_regulation of Gene_expression of Col7a1 1 0.01 0.7 0.16
67 INT202311 PDGFB Positive_regulation of Gene_expression of Fn1 1 0.02 0.7 0.16
68 INT146025 EGR1 Negative_regulation of Gene_expression of GDF15 1 0.28 0.81 0.15
69 INT312092 ELANE Positive_regulation of Gene_expression of EGR1 1 0.19 0.21 0.15
70 INT168806 Tlr4 Positive_regulation of Gene_expression of Egr1 1 0.18 0.3 0.15
71 INT223084 Binding of Pdgfa and Pdgfb 2 0.17 0.83 0.13
72 INT115140 PPARG Positive_regulation of EGR1 1 0.36 0.45 0.13
73 INT247267 Binding of Egr1 and Mecp2 1 0.12 0.18 0.13
74 INT321408 INS Positive_regulation of EGR1 1 0.03 2.36 0.13
75 INT115141 TGM7 Positive_regulation of EGR1 1 0.26 0.44 0.13
76 INT225024 PDGFB Positive_regulation of Gene_expression of Cxcl5 1 0.16 0.08 0.13
77 INT321414 INS Positive_regulation of Transcription of EGR1 1 0.03 2.36 0.13
78 INT321410 EGR1 Negative_regulation of Gene_expression of TNFSF10 1 0.10 2.07 0.12
79 INT154803 Gene_expression of EGR1 Positive_regulation of Positive_regulation of GDF15 1 0.33 0.84 0.12
80 INT263429 Pdgfb Positive_regulation of Localization of Abl1 1 0.01 0 0.12
81 INT48194 Pdgfb Positive_regulation of Setd1a 1 0.23 0 0.09
82 INT216130 SRF Positive_regulation of Gene_expression of EGR1 1 0.49 0.32 0.07
83 INT267016 Bdnf Positive_regulation of Egr1 1 0.12 0.09 0.07
84 INT223085 Binding of Pdgfb and Insrr 1 0.01 0.91 0.07
85 INT129184 Gene_expression of EGR1 Positive_regulation of ATF3 1 0.72 0.22 0.07
86 INT279280 Binding of PDGFA and PDGFB 1 0.06 0.9 0.06
87 INT343477 Epo Positive_regulation of Pdgfb 1 0.11 0.31 0.06
88 INT225023 PDGFB Regulation of Transcription of Ccl21 1 0.11 0 0.06
89 INT94852 PDGFB Regulation of Gene_expression of COL7A1 1 0.09 0.06 0.06
90 INT225022 PDGFB Regulation of Ccl21 1 0.11 0 0.06
91 INT343471 Epo Positive_regulation of Gene_expression of Pdgfb 1 0.11 0.31 0.06
92 INT129183 EGR1 Negative_regulation of Positive_regulation of ATF3 1 0.44 0.19 0.06
93 INT202310 Binding of PDGFB and Pdgfrb 1 0.11 0.39 0.04
94 INT263427 Pdgfb Positive_regulation of Phosphorylation of Rock1 1 0.00 0 0.04
95 INT223086 Binding of Pdgfb and Pdgfrb 1 0.33 0.46 0.04
96 INT60221 Agt Regulation of Gene_expression of Egr1 1 0.42 0 0.04
97 INT243766 Binding of Egr1 and Proc 1 0.01 0.2 0.03
98 INT279288 PDGFB Positive_regulation of NCOR2 1 0.00 0.52 0.03
99 INT279285 PDGFB Positive_regulation of TXK 1 0.05 0.52 0.03
100 INT313618 Binding of Acly and Pdgfb 1 0.00 0.18 0.03
101 INT328408 Nlrp1a Positive_regulation of Pdgfb 1 0.07 0.74 0.03
102 INT279277 PDGFB Positive_regulation of PDGFRB 1 0.14 0.52 0.03
103 INT184955 EGR1 Regulation of Regulation of TGFB1 1 0.39 0.3 0
104 INT332409 Egr1 Regulation of Hgf 1 0.26 0.14 0
105 INT177793 EGR1 Positive_regulation of Negative_regulation of TP53 1 0.18 0.44 0
106 INT240122 Nab2 Regulation of Egr1 1 0.09 0.59 0
107 INT332408 Binding of Egr1 and Hgf 1 0.35 0.14 0
108 INT243770 Egr1 Regulation of Nab2 1 0.28 0.09 0
109 INT312114 EGR1 Positive_regulation of Positive_regulation of PTGES 1 0.32 0 0
110 INT259811 Narp Positive_regulation of Gene_expression of Egr1 1 0.26 0.86 0
111 INT269014 Binding of EGR1 and COPD 1 0.12 0.96 0
112 INT328411 Nlrp1a Negative_regulation of Pdgfb 1 0.08 0.39 0
113 INT224993 INCENP Regulation of PDGFB 1 0.00 0 0
114 INT223083 Gene_expression of Pdgfb Positive_regulation of Cm3 1 0.02 1 0
115 INT286770 Skil Negative_regulation of Egr1 1 0.08 0.75 0
116 INT225020 Binding of PDGFB and Mtpn 1 0.01 0.15 0
117 INT277703 Binding of Pdgfrb and Pdgfb 1 0.02 0.23 0
118 INT285641 Zfp36 Negative_regulation of Egr1 1 0.06 0.28 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular response to mycophenolic acid. They are ordered first by their pain relevance and then by number of times they were reported in cellular response to mycophenolic acid. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13
2 INT5862 Positive_regulation of Egr1 82 0.70 30.4 33.96
3 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93
4 INT57874 Gene_expression of Egr1 113 0.78 68.46 24.95
5 INT57878 Positive_regulation of Gene_expression of Egr1 36 0.70 20.42 14.45
6 INT49660 Positive_regulation of EGR1 54 0.69 32.17 9.89
7 INT57876 Positive_regulation of Egr1 46 0.70 25.6 9.41
8 INT73021 Gene_expression of EGR1 43 0.77 24.65 9.18
9 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
10 INT6055 Transcription of Egr1 47 0.69 3.61 7.68
11 INT6057 Negative_regulation of Gene_expression of Egr1 17 0.57 4.17 7.17
12 INT47707 Negative_regulation of Egr1 9 0.41 0.17 7.03
13 INT73022 Positive_regulation of Gene_expression of EGR1 21 0.69 10.61 6.5
14 INT5860 Regulation of Gene_expression of Egr1 20 0.62 3.02 6.38
15 INT47704 Regulation of Egr1 17 0.60 2.43 5.18
16 INT47706 Negative_regulation of Positive_regulation of Egr1 9 0.41 6.11 5.1
17 INT57376 Transcription of EGR1 20 0.69 12.94 4.84
18 INT51944 Positive_regulation of Transcription of Egr1 12 0.49 1.96 4.72
19 INT117936 Regulation of Gene_expression of Egr1 18 0.60 9.37 4.45
20 INT74531 Regulation of PDGFB 14 0.26 7.57 4.38
21 INT123502 Binding of Egr1 11 0.35 6.7 3.77
22 INT70897 Positive_regulation of Gene_expression of PDGFB 15 0.57 13.04 3.52
23 INT70895 Localization of PDGFB 20 0.52 8.98 3.4
24 INT70885 Gene_expression of Pdgfb 48 0.67 42.27 3.19
25 INT74527 Positive_regulation of PDGFB 14 0.38 13.31 2.54
26 INT96640 Negative_regulation of Gene_expression of Egr1 13 0.43 7.22 2.48
27 INT98634 Positive_regulation of Positive_regulation of EGR1 9 0.68 3.43 2.47
28 INT74262 Negative_regulation of Egr1 15 0.57 7.51 2.41
29 INT15243 Regulation of Egr1 19 0.61 7.6 2.13
30 INT80599 Regulation of Positive_regulation of Egr1 3 0.28 0.46 2.09
31 INT73023 Binding of EGR1 7 0.48 4.23 1.86
32 INT57375 Regulation of EGR1 5 0.40 1.94 1.78
33 INT57875 Positive_regulation of Positive_regulation of Egr1 6 0.49 2.74 1.75
34 INT57877 Negative_regulation of Positive_regulation of Egr1 4 0.42 1.63 1.57
35 INT74528 Negative_regulation of PDGFB 11 0.40 10.34 1.48
36 INT74530 Transcription of PDGFB 7 0.65 4.56 1.47
37 INT53003 Positive_regulation of Positive_regulation of Egr1 6 0.64 2.36 1.44
38 INT98635 Negative_regulation of Gene_expression of EGR1 5 0.58 2.2 1.42
39 INT44529 Positive_regulation of Pdgfb 11 0.43 7.98 1.36
40 INT141344 Transcription of Egr1 11 0.70 5.59 1.34
41 INT192349 Negative_regulation of Gene_expression of PDGFB 5 0.31 2.64 1.25
42 INT70886 Positive_regulation of Gene_expression of Pdgfb 13 0.45 12.57 1.17
43 INT98633 Negative_regulation of Transcription of EGR1 3 0.43 0.79 1.11
44 INT123503 Positive_regulation of Binding of Egr1 3 0.13 2.34 1.04
45 INT123501 Negative_regulation of Binding of Egr1 2 0.12 2.04 0.99
46 INT51947 Regulation of Transcription of Egr1 2 0.59 0.15 0.96
47 INT98638 Positive_regulation of Transcription of EGR1 3 0.49 2.83 0.91
48 INT98636 Negative_regulation of Positive_regulation of EGR1 3 0.58 2.21 0.73
49 INT202307 Regulation of Gene_expression of PDGFB 2 0.26 1.24 0.71
50 INT6050 Localization of Egr1 4 0.68 0.53 0.7
51 INT141341 Binding of Egr1 5 0.48 2.65 0.67
52 INT102686 Phosphorylation of Egr1 3 0.59 2.57 0.64
53 INT74529 Binding of PDGFB 13 0.36 7.41 0.62
54 INT277699 Gene_expression of Pdgfb 5 0.20 4.84 0.59
55 INT73020 Positive_regulation of Binding of EGR1 1 0.49 0.46 0.56
56 INT202306 Negative_regulation of Localization of PDGFB 2 0.25 0.76 0.55
57 INT98632 Negative_regulation of EGR1 6 0.42 3.38 0.54
58 INT81061 Regulation of Negative_regulation of Egr1 1 0.22 0 0.53
59 INT202309 Regulation of Localization of PDGFB 1 0.36 0.92 0.49
60 INT168801 Localization of Egr1 4 0.78 0.7 0.48
61 INT223081 Negative_regulation of Gene_expression of Pdgfb 2 0.37 3.07 0.47
62 INT313617 Positive_regulation of Pdgfb 4 0.35 1.53 0.46
63 INT141342 Negative_regulation of Transcription of Egr1 4 0.43 2.39 0.45
64 INT70884 Localization of Pdgfb 8 0.35 6.22 0.42
65 INT243756 Regulation of Positive_regulation of Egr1 7 0.45 1.18 0.4
66 INT76143 Positive_regulation of Regulation of PDGFB 1 0.01 0.08 0.4
67 INT74532 Positive_regulation of Transcription of PDGFB 1 0.57 0.73 0.4
68 INT317875 Binding of Pdgfb 3 0.10 1.15 0.36
69 INT153261 Positive_regulation of Localization of PDGFB 2 0.37 1.98 0.36
70 INT144968 Positive_regulation of Localization of EGR1 1 0.69 0.82 0.35
71 INT144970 Localization of EGR1 1 0.80 0.82 0.34
72 INT188498 Negative_regulation of Transcription of Egr1 3 0.41 0.14 0.32
73 INT224441 Negative_regulation of Pdgfb 2 0.33 1.61 0.27
74 INT177838 Regulation of Gene_expression of EGR1 2 0.17 2.38 0.25
75 INT141343 Positive_regulation of Transcription of Egr1 1 0.47 1.43 0.24
76 INT349702 Positive_regulation of Transcription of Pdgfb 1 0.35 0 0.23
77 INT277701 Localization of Pdgfb 3 0.23 1.49 0.22
78 INT349701 Transcription of Pdgfb 1 0.40 0 0.22
79 INT346813 Positive_regulation of Regulation of Egr1 1 0.49 0.27 0.21
80 INT102793 Regulation of Phosphorylation of Egr1 1 0.33 0 0.17
81 INT115159 Regulation of Positive_regulation of EGR1 1 0.20 0.18 0.16
82 INT225004 Regulation of Positive_regulation of PDGFB 1 0.26 0.1 0.13
83 INT346814 Phosphorylation of Egr1 1 0.62 0 0.12
84 INT346807 Regulation of Transcription of Egr1 1 0.44 0.27 0.09
85 INT319408 Negative_regulation of Binding of PDGFB 1 0.15 0.89 0.09
86 INT320268 Positive_regulation of Negative_regulation of EGR1 1 0.26 0.69 0.07
87 INT355724 Negative_regulation of Positive_regulation of Pdgfb 1 0.13 0.6 0.07
88 INT319411 Negative_regulation of Transcription of PDGFB 1 0.15 1.03 0.07
89 INT277702 Positive_regulation of Gene_expression of Pdgfb 2 0.10 0.55 0.05
90 INT225003 Positive_regulation of Binding of PDGFB 1 0.29 0 0.03
91 INT202308 Phosphorylation of PDGFB 1 0.34 0.43 0.03
92 INT223077 Regulation of Pdgfb 1 0.23 0.34 0
93 INT343453 Phosphorylation of Pdgfb 1 0.13 0.1 0
94 INT277700 Binding of Pdgfb 1 0.09 0.67 0
95 INT277696 Regulation of Positive_regulation of Pdgfb 1 0.03 0.52 0
96 INT285638 Regulation of Negative_regulation of Egr1 1 0.37 0.14 0
97 INT223079 Regulation of Gene_expression of Pdgfb 1 0.23 1.17 0
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