GO:0071548

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Name response to dexamethasone stimulus
Categary Process
Go Slim No
Go Link GO:0071548
Unique Molecular Interactions 87
Total Molecular Interactions 109
Total Single Events 2575
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to dexamethasone stimulus. They are ordered first by their pain relevance and then by number of times they were reported for response to dexamethasone stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
2 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57
3 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
4 INT88875 Ifng Positive_regulation of Transcription of Nos2 1 0.02 0.27 1.03
5 INT88887 IRF6 Positive_regulation of Transcription of Nos2 1 0.21 0.27 1.02
6 INT88874 Ifng Regulation of Nos2 1 0.01 0.26 1.01
7 INT88884 IRF6 Regulation of Nos2 1 0.12 0.26 1
8 INT88886 IRF6 Positive_regulation of Nos2 1 0.22 0.26 1
9 INT88888 Regulation of IRF6 Positive_regulation of Nos2 1 0.20 0.26 1
10 INT108687 Nfkb1 Regulation of Positive_regulation of Nos2 1 0.50 1.28 0.88
11 INT108686 Nfkb1 Regulation of Nos2 1 0.69 1.27 0.88
12 INT102931 Nos3 Positive_regulation of Nos2 1 0.43 1.63 0.83
13 INT65807 Nr3c1 Positive_regulation of Cyp3a23/3a1 1 0.14 0 0.82
14 INT88885 IRF6 Positive_regulation of Gene_expression of Nos2 1 0.21 0.1 0.81
15 INT88878 Negative_regulation of Nfkb1 Positive_regulation of Gene_expression of Nos2 1 0.06 0.1 0.81
16 INT128815 Mapk14 Regulation of Gene_expression of Nos2 1 0.21 0.46 0.74
17 INT128813 Mapk8 Regulation of Gene_expression of Nos2 1 0.23 0.46 0.74
18 INT187522 ATIC Negative_regulation of Gene_expression of Nos2 1 0.02 1.46 0.7
19 INT220035 Nos1 Positive_regulation of Nos2 1 0.29 0.45 0.66
20 INT266489 Dcps Positive_regulation of Gene_expression of Nos2 1 0.06 3.43 0.63
21 INT128812 Mapk8 Negative_regulation of Gene_expression of Nos2 1 0.19 0.37 0.61
22 INT128817 Ephb1 Negative_regulation of Gene_expression of Nos2 1 0.16 0.37 0.61
23 INT124831 Fbp1 Positive_regulation of Nos2 1 0.36 0.64 0.61
24 INT339072 Eae1 Positive_regulation of Gene_expression of Nos2 1 0.02 3.76 0.59
25 INT128810 Il1b Positive_regulation of Gene_expression of Nos2 1 0.04 0.31 0.59
26 INT143426 Positive_regulation of B4GALNT1 Negative_regulation of Gene_expression of Nos2 1 0.00 0.83 0.58
27 INT151459 Olr1745 Negative_regulation of Gene_expression of Nos2 1 0.04 0.82 0.57
28 INT78588 Positive_regulation of Binding of Nfkb1 and Nos2 1 0.01 0.33 0.56
29 INT81546 TNF Positive_regulation of Gene_expression of Nos2 1 0.04 0.54 0.56
30 INT78587 Binding of Nfkb1 and Nos2 1 0.01 0.33 0.55
31 INT78590 Nos2 Positive_regulation of PTGS1 2 0.00 0.85 0.5
32 INT132060 NBN Positive_regulation of Nos2 1 0.01 0.21 0.49
33 INT148634 Abat Negative_regulation of Transcription of Nos2 1 0.19 0.52 0.44
34 INT97789 Positive_regulation of Cnr1 Negative_regulation of Gene_expression of Nos2 1 0.12 0.23 0.4
35 INT187487 Cebpg Positive_regulation of Gene_expression of Nos2 1 0.03 0.38 0.4
36 INT81300 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.02 0.38 0.39
37 INT61954 IFNA1 Positive_regulation of Nos2 1 0.05 0.46 0.38
38 INT97790 Foxm1 Negative_regulation of Gene_expression of Nos2 1 0.03 0.16 0.36
39 INT89500 Nos2 Positive_regulation of Il6 1 0.04 1.07 0.35
40 INT187488 Positive_regulation of Ros1 Positive_regulation of Gene_expression of Nos2 1 0.01 0.88 0.35
41 INT276214 Binding of Nos2 and Nfkb1 1 0.12 0.31 0.34
42 INT89505 Nos2 Positive_regulation of Ptgs2 1 0.05 1.07 0.34
43 INT276209 Negative_regulation of Binding of Nos2 and Nfkb1 1 0.14 0.31 0.34
44 INT89502 Positive_regulation of Nos2 Positive_regulation of Ptgs2 1 0.05 1.07 0.34
45 INT115261 Gene_expression of Nos2 Positive_regulation of Positive_regulation of Npr1 1 0.05 0.67 0.31
46 INT71309 Il1a Positive_regulation of Nos2 1 0.21 0.26 0.26
47 INT273055 Plat Positive_regulation of Gene_expression of Nos2 1 0.01 1.34 0.23
48 INT132382 Nos2 Positive_regulation of PTGS2 1 0.02 0.1 0.23
49 INT133163 Nos2 Regulation of Tnf 1 0.36 0.97 0.22
50 INT104846 TNF Positive_regulation of Nos2 1 0.10 0.83 0.22
51 INT333397 CFD Negative_regulation of Gene_expression of Nos2 1 0.04 0.8 0.22
52 INT222568 Vip Negative_regulation of Transcription of Nos2 1 0.06 0.3 0.19
53 INT222473 Mzb1 Negative_regulation of Transcription of Nos2 1 0.04 0.29 0.19
54 INT52306 Nr3c1 Negative_regulation of Transcription of Penk 1 0.26 0 0.18
55 INT81302 Tlr4 Negative_regulation of Gene_expression of Nos2 1 0.02 0.18 0.18
56 INT81298 Ifng Negative_regulation of Gene_expression of Nos2 1 0.40 0.18 0.18
57 INT81297 Positive_regulation of Pparg Regulation of Gene_expression of Nos2 1 0.23 0.17 0.17
58 INT75036 Slc6a14 Negative_regulation of Cyp11b1 1 0.00 0.17 0.17
59 INT94864 Regulation of Litaf Positive_regulation of Nos2 1 0.05 0.05 0.15
60 INT94865 Litaf Positive_regulation of Nos2 1 0.08 0.05 0.15
61 INT139343 Il1b Positive_regulation of Nos2 1 0.09 1.26 0.14
62 INT194975 Negative_regulation of Alox5 Negative_regulation of Gene_expression of Nos2 1 0.13 0.69 0.13
63 INT129094 Binding of GRP and Pik3r1 1 0.00 0.49 0.12
64 INT129075 Binding of Pik3r1 and Lyn 1 0.00 0.47 0.12
65 INT194976 Alox5 Regulation of Gene_expression of Nos2 1 0.07 0.56 0.12
66 INT151423 Tfrc Positive_regulation of Gene_expression of Nos2 1 0.24 0.49 0.1
67 INT92956 Edn1 Regulation of Positive_regulation of Nos2 1 0.18 0.17 0.09
68 INT92957 Edn1 Regulation of Gene_expression of Nos2 1 0.18 0.17 0.09
69 INT75033 Slc6a14 Negative_regulation of Gene_expression of Cyp11b1 1 0.00 0.08 0.08
70 INT245642 Nr3c1 Regulation of Gene_expression of Hpse 1 0.05 1.33 0.08
71 INT244291 Nos2 Positive_regulation of Positive_regulation of Hmox1 1 0.34 0.07 0.07
72 INT249955 Cpa1 Positive_regulation of Nos2 1 0.02 0.33 0.06
73 INT181568 Positive_regulation of Mapk1 Positive_regulation of Gene_expression of Nos2 1 0.16 1.35 0.05
74 INT96044 Rasgrp1 Positive_regulation of Gene_expression of Nos2 1 0.14 0.05 0
75 INT249935 Nos3 Regulation of Nos2 1 0.25 0.19 0
76 INT290909 Negative_regulation of Binding of Nos2 and Ntn1 1 0.12 0 0
77 INT111719 Cd68 Positive_regulation of Nos2 1 0.03 0.17 0
78 INT290903 Binding of Nos2 and Ntn1 1 0.10 0 0
79 INT143286 Negative_regulation of Nfkb1 Negative_regulation of Gene_expression of Nos2 1 0.01 0 0
80 INT166848 Tnf Positive_regulation of Nos2 1 0.23 0 0
81 INT290898 Shh Positive_regulation of Nos2 1 0.46 0.05 0
82 INT295292 Jun Positive_regulation of Transcription of Nos2 1 0.01 0 0
83 INT295291 Mapk14 Positive_regulation of Gene_expression of Nos2 1 0.04 0.05 0
84 INT249952 Cpa1 Regulation of Nos2 1 0.02 0.08 0
85 INT249934 Nos1 Regulation of Nos2 1 0.20 0.19 0
86 INT290899 Prkcg Regulation of Positive_regulation of Nos2 1 0.14 0 0
87 INT223734 Binding of VEGFA and Nos2 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to dexamethasone stimulus. They are ordered first by their pain relevance and then by number of times they were reported in response to dexamethasone stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08
2 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87
3 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53
4 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15
5 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67
6 INT61953 Transcription of Nos2 101 0.72 46.64 25.49
7 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01
8 INT61949 Regulation of Nos2 74 0.58 34.08 16.7
9 INT48956 Negative_regulation of Positive_regulation of Nos2 34 0.46 13.15 11.15
10 INT70850 Positive_regulation of Transcription of Nos2 30 0.70 18.95 9.68
11 INT72337 Positive_regulation of Positive_regulation of Nos2 37 0.65 17.02 8.11
12 INT7564 Positive_regulation of Nr3c1 16 0.68 4.98 6.25
13 INT52814 Negative_regulation of Nr3c1 9 0.57 5.69 5.41
14 INT77252 Gene_expression of Nr3c1 17 0.67 9.71 5.38
15 INT73608 Localization of Nos2 21 0.75 9.58 5.05
16 INT61950 Regulation of Positive_regulation of Nos2 17 0.43 9.01 4.87
17 INT89784 Regulation of Transcription of Nos2 14 0.42 8.39 4.24
18 INT49712 Regulation of Nr3c1 10 0.28 5.65 4.06
19 INT61952 Negative_regulation of Transcription of Nos2 17 0.54 5.1 3.34
20 INT126223 Binding of Nos2 17 0.37 6 3.22
21 INT72757 Negative_regulation of Negative_regulation of Nos2 8 0.42 4.23 2.68
22 INT77250 Positive_regulation of Gene_expression of Nr3c1 4 0.44 3.32 2.64
23 INT79609 Positive_regulation of Negative_regulation of Nos2 5 0.49 3.6 2.43
24 INT8484 Localization of Nr3c1 8 0.53 3.12 2.32
25 INT99039 Negative_regulation of Gene_expression of Nr3c1 2 0.37 1.96 2.08
26 INT135313 Regulation of Gene_expression of Nr3c1 3 0.39 3.44 1.94
27 INT52305 Binding of Nr3c1 7 0.15 3.95 1.9
28 INT181574 Phosphorylation of Nos2 9 0.70 2.92 1.55
29 INT49448 Positive_regulation of Positive_regulation of Nr3c1 1 0.38 0 1.55
30 INT7578 Transcription of Nr3c1 5 0.32 0.43 1.47
31 INT61951 Regulation of Negative_regulation of Nos2 5 0.58 3.08 1.39
32 INT248304 Positive_regulation of Localization of Nr3c1 2 0.10 1.39 0.87
33 INT7576 Positive_regulation of Transcription of Nr3c1 1 0.19 0.3 0.62
34 INT96323 Regulation of Transcription of Nr3c1 1 0.20 0 0.59
35 INT96037 Positive_regulation of Localization of Nos2 2 0.49 0.78 0.52
36 INT349037 Regulation of Phosphorylation of Nos2 1 0.39 1.02 0.51
37 INT290850 Regulation of Positive_regulation of Nr3c1 1 0.12 0.75 0.47
38 INT52815 Regulation of Negative_regulation of Nr3c1 1 0.08 0.05 0.43
39 INT208368 Negative_regulation of Regulation of Nos2 1 0.42 0.35 0.42
40 INT106275 Regulation of Localization of Nos2 1 0.25 0.38 0.32
41 INT132377 Negative_regulation of Binding of Nos2 5 0.29 0.75 0.28
42 INT117878 Positive_regulation of Regulation of Nos2 3 0.41 1.35 0.25
43 INT124200 Negative_regulation of Localization of Nos2 1 0.22 0.7 0.25
44 INT11846 Regulation of Cyp11b1 3 0.15 0 0.19
45 INT317595 Negative_regulation of Transcription of Nr3c1 1 0.05 0.14 0.18
46 INT268931 Positive_regulation of Regulation of Nr3c1 1 0.10 0.34 0.13
47 INT129082 Positive_regulation of Pik3r1 1 0.00 0.47 0.11
48 INT75015 Gene_expression of Cyp11b1 1 0.01 0.08 0.08
49 INT75021 Negative_regulation of Gene_expression of Cyp11b1 1 0.01 0.08 0.08
50 INT134850 Positive_regulation of Negative_regulation of Nr3c1 1 0.02 0 0.04
51 INT349470 Regulation of Binding of Nos2 1 0.35 0 0
52 INT245628 Regulation of Localization of Nr3c1 1 0.15 0 0
53 INT109125 Positive_regulation of Protein_catabolism of Nos2 1 0.39 0 0
54 INT109126 Protein_catabolism of Nos2 1 0.55 0 0
55 INT97919 Negative_regulation of Cyp11b1 1 0.33 0 0
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