GO:0071791

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Name chemokine (C-C motif) ligand 5 binding
Categary Function
Go Slim No
Go Link GO:0071791
Unique Molecular Interactions 80
Total Molecular Interactions 130
Total Single Events 773
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for chemokine (C-C motif) ligand 5 binding. They are ordered first by their pain relevance and then by number of times they were reported for chemokine (C-C motif) ligand 5 binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
2 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
3 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
4 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
5 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47
6 INT222213 TFAM Positive_regulation of Gene_expression of Ccr1 1 0.02 3.96 1.4
7 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03
8 INT106248 Binding of CCR5 and YY1 1 0.54 0.19 0.98
9 INT275406 Binding of ITIH4 and Ccr5 1 0.09 2.88 0.97
10 INT275390 Binding of Ccr5 and Htatsf1 1 0.01 3.26 0.97
11 INT128652 ITIH4 Regulation of Gene_expression of CCR5 1 0.36 1.46 0.93
12 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
13 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
14 INT222243 Negative_regulation of Binding of Trpv1 and Ccr5 1 0.21 0.57 0.86
15 INT222244 Binding of Trpv1 and Ccr5 1 0.19 0.57 0.86
16 INT209035 Il2 Positive_regulation of Ccr1 1 0.00 0.38 0.73
17 INT209038 Il4 Positive_regulation of Ccr1 1 0.01 0.38 0.73
18 INT209065 Il3 Positive_regulation of Ccr1 1 0.00 0.38 0.73
19 INT209031 Il12b Positive_regulation of Ccr1 1 0.02 0.37 0.72
20 INT209041 Il10 Positive_regulation of Ccr1 1 0.01 0.37 0.72
21 INT209060 Il6 Positive_regulation of Ccr1 1 0.01 0.38 0.72
22 INT123494 Binding of Egr1 and Ccr5 1 0.04 0.94 0.71
23 INT222211 TFAM Positive_regulation of Ccr1 1 0.02 1.89 0.68
24 INT297307 Negative_regulation of Binding of Ccr1 and Ccl3 1 0.27 0.73 0.67
25 INT297313 Negative_regulation of Binding of Ccr1 and Ccl5 1 0.28 0.74 0.67
26 INT106247 Binding of CCR5 and CCL4 1 0.54 0.06 0.64
27 INT244232 Binding of Ccr5 and Ccl4 3 0.17 1.48 0.55
28 INT97635 ABCF1 Positive_regulation of Localization of CCR1 1 0.05 0.51 0.55
29 INT275387 Binding of Lamp1 and Ccr5 1 0.01 1.45 0.52
30 INT275405 Binding of GOLPH3 and Ccr5 1 0.00 1.46 0.52
31 INT275407 Binding of ERVW-1 and Ccr5 1 0.00 1.74 0.46
32 INT178664 Binding of CCR5 and TH1L 1 0.04 1.04 0.44
33 INT181081 Binding of Ccr1 and Darc 1 0.01 1.08 0.39
34 INT123511 TIAF1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0.6 0.37
35 INT123495 Negative_regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
36 INT123493 Regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
37 INT189494 Negative_regulation of Ccr5 Negative_regulation of Gene_expression of Hand1 1 0.16 0.66 0.32
38 INT244233 Ccr1 Positive_regulation of Cxcr1 1 0.16 0.08 0.32
39 INT284229 Binding of ITIH4 and Ccr5 1 0.10 0.27 0.31
40 INT268766 Tlr4 Positive_regulation of Gene_expression of Ccr1 1 0.04 0.4 0.26
41 INT275553 Negative_regulation of Binding of Ccr5 and Ccl3 1 0.05 0.73 0.26
42 INT268768 Mip Regulation of Positive_regulation of Ccr1 1 0.44 0.83 0.23
43 INT170993 IL10 Positive_regulation of Gene_expression of CCR1 1 0.12 0.34 0.22
44 INT181445 Binding of Ccr5 and Hand1 1 0.12 1.01 0.22
45 INT182634 Binding of CCR5 and MIP 2 0.39 1.29 0.2
46 INT158209 Binding of CCR1 and AHSA1 1 0.17 0.3 0.2
47 INT158225 Binding of CCR1 and MAPK1 1 0.18 0.3 0.2
48 INT158231 TNFSF14 Positive_regulation of CCR1 1 0.07 0.3 0.2
49 INT158210 Binding of CCR1 and TNFSF14 1 0.05 0.3 0.2
50 INT158212 Negative_regulation of Binding of CCR1 and AHSA1 1 0.20 0.3 0.2
51 INT158200 Positive_regulation of Binding of CCR1 and AHSA1 1 0.23 0.3 0.2
52 INT158201 Positive_regulation of Binding of CCR1 and TNFSF14 1 0.07 0.3 0.2
53 INT158221 Positive_regulation of Binding of CCR1 and MAPK1 1 0.25 0.3 0.2
54 INT158230 Negative_regulation of Binding of CCR1 and TNFSF14 1 0.06 0.3 0.2
55 INT158219 Negative_regulation of Binding of CCR1 and MAPK1 1 0.21 0.3 0.2
56 INT23585 Binding of KRIT1 and CCR1 1 0.40 0.97 0.19
57 INT244240 Binding of IL8 and Ccr5 1 0.03 0.05 0.18
58 INT172250 Binding of APLNR and CCR1 1 0.12 0 0.17
59 INT284230 Positive_regulation of Binding of ITIH4 and Ccr5 1 0.10 0 0.17
60 INT88311 ITIH4 Positive_regulation of CCR5 1 0.49 1.57 0.16
61 INT284226 Negative_regulation of Binding of Ccr5 and Hivan1 1 0.01 0.27 0.14
62 INT284217 Binding of Ccr5 and Hivan1 1 0.01 0.27 0.14
63 INT352417 Ccl2 Positive_regulation of Ccr5 1 0.06 0.26 0.14
64 INT333652 Binding of Ccr5 and Msc 1 0.10 0.07 0.13
65 INT268765 Tlr4 Positive_regulation of Positive_regulation of Ccr1 1 0.04 0.27 0.13
66 INT284219 Binding of Ccr5 and Avpr1b 1 0.01 0.46 0.12
67 INT284208 Binding of Ccr5 and Eclc 1 0.08 0.3 0.12
68 INT241748 CCR5 Regulation of CD4 1 0.21 0.39 0.11
69 INT284220 Binding of Ccr5 and Mela 1 0.12 0.23 0.1
70 INT284222 Binding of Ccr5 and Musd1 1 0.01 0.5 0.07
71 INT284216 Binding of Ccr5 and Arhgap4 1 0.02 0.31 0.07
72 INT284209 Negative_regulation of Binding of Ccr5 and Mela 1 0.14 0.12 0.05
73 INT251296 Binding of CCR5 and ITIH4 1 0.16 0.08 0.04
74 INT284225 Binding of Cd4 and Ccr5 1 0.30 0.26 0.04
75 INT241749 ITIH4 Negative_regulation of Binding of CCR5 1 0.16 0.71 0.04
76 INT183767 Csf2 Negative_regulation of Transcription of CCR5 1 0.17 0.92 0.03
77 INT183758 INCENP Negative_regulation of Transcription of CCR5 1 0.00 0.93 0.03
78 INT121652 Binding of CCR5 and CXCL12 1 0.33 0.2 0
79 INT328477 Mkrn1 Positive_regulation of CCR5 1 0.01 0.69 0
80 INT336168 Binding of CCR5 and HIVEP1 1 0.01 0.44 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for chemokine (C-C motif) ligand 5 binding. They are ordered first by their pain relevance and then by number of times they were reported in chemokine (C-C motif) ligand 5 binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT88322 Gene_expression of CCR5 111 0.78 77.36 39.84
2 INT141612 Gene_expression of Ccr1 92 0.77 72.09 24.14
3 INT167679 Gene_expression of Ccr5 74 0.75 59.03 18.16
4 INT89293 Positive_regulation of Gene_expression of CCR5 29 0.70 22.14 15
5 INT87393 Gene_expression of Ccr5 19 0.65 11 10.51
6 INT89292 Positive_regulation of CCR5 27 0.70 15.12 8.59
7 INT166881 Positive_regulation of Ccr1 31 0.69 18.14 7.9
8 INT91758 Binding of CCR5 28 0.45 20.16 7.07
9 INT153268 Positive_regulation of Ccr5 25 0.66 19 7.02
10 INT93144 Gene_expression of CCR1 18 0.75 14.69 6.84
11 INT141611 Positive_regulation of Gene_expression of Ccr1 25 0.69 20.32 6.42
12 INT107315 Negative_regulation of CCR5 22 0.57 13.82 6.11
13 INT120089 Negative_regulation of Ccr5 7 0.58 10.36 5.91
14 INT103847 Positive_regulation of Ccr5 11 0.55 6.04 5.79
15 INT181406 Binding of Ccr5 16 0.45 17 5.78
16 INT181022 Binding of Ccr1 15 0.37 10.69 5.37
17 INT150237 Localization of Ccr1 10 0.75 9.25 4.72
18 INT65700 Localization of CCR1 7 0.51 4 3.91
19 INT103843 Positive_regulation of Gene_expression of Ccr5 5 0.42 2.31 3.89
20 INT166879 Localization of Ccr5 4 0.71 3.62 2.97
21 INT110233 Regulation of Gene_expression of CCR5 6 0.34 7.14 2.76
22 INT106433 Regulation of CCR5 11 0.59 6.93 2.75
23 INT87395 Binding of Ccr5 5 0.29 2.5 2.6
24 INT113775 Negative_regulation of Gene_expression of CCR5 6 0.43 3.97 2.28
25 INT181356 Positive_regulation of Gene_expression of Ccr5 11 0.66 8.3 2.24
26 INT23588 Positive_regulation of CCR1 6 0.67 4.44 2.24
27 INT181402 Negative_regulation of Ccr1 8 0.42 7 2.2
28 INT96743 Transcription of Ccr5 2 0.54 2.72 2.17
29 INT112970 Regulation of Ccr1 8 0.29 7.77 1.93
30 INT87394 Negative_regulation of Ccr5 3 0.32 1.3 1.74
31 INT241757 Localization of CCR5 6 0.71 5.7 1.14
32 INT268754 Negative_regulation of Gene_expression of Ccr1 5 0.43 2.76 1.13
33 INT268753 Negative_regulation of Positive_regulation of Ccr1 1 0.42 2.59 0.96
34 INT87396 Negative_regulation of Gene_expression of Ccr5 1 0.12 1.02 0.92
35 INT189482 Regulation of Gene_expression of Ccr5 4 0.44 3.38 0.86
36 INT160410 Positive_regulation of Positive_regulation of Ccr5 2 0.38 1.31 0.83
37 INT181359 Transcription of Ccr1 4 0.53 1.66 0.8
38 INT268746 Positive_regulation of Binding of Ccr1 1 0.50 1.81 0.79
39 INT171946 Positive_regulation of Binding of CCR5 1 0.47 3.86 0.66
40 INT115892 Positive_regulation of Phosphorylation of Ccr5 1 0.00 0 0.66
41 INT115896 Phosphorylation of Ccr5 1 0.01 0 0.65
42 INT181364 Regulation of Ccr5 3 0.32 1.81 0.62
43 INT189481 Regulation of Gene_expression of Ccr1 3 0.45 1.97 0.58
44 INT172297 Binding of CCR1 1 0.36 0.08 0.56
45 INT97637 Positive_regulation of Localization of CCR1 1 0.08 0.51 0.55
46 INT260124 Positive_regulation of Positive_regulation of CCR5 1 0.14 0.84 0.51
47 INT103844 Regulation of Gene_expression of Ccr5 1 0.22 0.55 0.51
48 INT181376 Negative_regulation of Gene_expression of Ccr5 3 0.41 2.12 0.49
49 INT182225 Transcription of CCR1 1 0.57 0.45 0.47
50 INT181397 Transcription of Ccr5 2 0.62 1.33 0.46
51 INT87392 Regulation of Ccr5 1 0.17 0.53 0.46
52 INT222240 Positive_regulation of Transcription of Ccr5 1 0.37 0.7 0.4
53 INT268761 Positive_regulation of Positive_regulation of Ccr1 1 0.43 1.51 0.39
54 INT322707 Protein_catabolism of Ccr5 1 0.22 0.32 0.37
55 INT171023 Negative_regulation of Gene_expression of CCR1 2 0.37 1.53 0.36
56 INT221044 Positive_regulation of Negative_regulation of CCR5 1 0.19 0.62 0.35
57 INT171025 Negative_regulation of Localization of CCR1 1 0.37 0.4 0.25
58 INT268747 Positive_regulation of Localization of Ccr1 1 0.43 0.8 0.23
59 INT104449 Transcription of CCR5 4 0.53 2.73 0.21
60 INT268750 Positive_regulation of Transcription of Ccr1 2 0.46 0.26 0.21
61 INT23591 Regulation of CCR1 1 0.26 0.96 0.19
62 INT268764 Regulation of Positive_regulation of Ccr1 1 0.45 0.83 0.18
63 INT181340 Negative_regulation of Negative_regulation of Ccr1 1 0.28 0.67 0.18
64 INT284203 Positive_regulation of Negative_regulation of Ccr5 1 0.41 0.41 0.18
65 INT107316 Negative_regulation of Positive_regulation of CCR5 2 0.41 1.96 0.17
66 INT158243 Positive_regulation of Positive_regulation of CCR1 1 0.39 0.26 0.17
67 INT158248 Negative_regulation of Positive_regulation of CCR1 1 0.36 0.26 0.17
68 INT284206 Negative_regulation of Negative_regulation of Ccr5 1 0.40 0 0.12
69 INT241759 Negative_regulation of Binding of CCR5 2 0.41 0.94 0.11
70 INT285555 Positive_regulation of Gene_expression of CCR1 1 0.16 1.11 0.1
71 INT322703 Negative_regulation of Binding of Ccr5 1 0.32 0.41 0.09
72 INT268757 Phosphorylation of Ccr1 1 0.81 0.08 0.08
73 INT284205 Phosphorylation of Ccr5 1 0.59 0.08 0.04
74 INT183763 Negative_regulation of Transcription of CCR5 1 0.15 0.92 0.03
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