GO:0071930

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Name negative regulation of transcription involved in G1/S phase of mitotic cell cycle
Categary Process
Go Slim No
Go Link GO:0071930
Unique Molecular Interactions 97
Total Molecular Interactions 144
Total Single Events 779
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of transcription involved in G1/S phase of mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of transcription involved in G1/S phase of mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT54942 Rb1 Regulation of Gab1 1 0.02 0.39 0.59
2 INT164262 TGM7 Negative_regulation of E2F1 1 0.16 1.08 0.53
3 INT163040 E2f1 Positive_regulation of Transcription of Oprm1 1 0.00 0 0.46
4 INT306824 Binding of E2F1 and E2F2 1 0.15 0.15 0.46
5 INT85782 Rb1 Regulation of PRKG1 1 0.00 0.38 0.37
6 INT85778 Rb1 Regulation of Prkaca 1 0.00 0.38 0.36
7 INT85779 Rb1 Regulation of Prkcg 1 0.01 0.38 0.36
8 INT204080 HP Negative_regulation of Phosphorylation of Rb1 1 0.00 3.53 0.34
9 INT54943 Gab1 Regulation of Rb1 1 0.02 0.2 0.31
10 INT119264 Binding of RB1 and PPM1E 1 0.00 0.46 0.17
11 INT221899 Rb1 Positive_regulation of Transcription of Ccl20 1 0.01 0.62 0.16
12 INT221908 Rb1 Positive_regulation of Transcription of TNIP2 1 0.01 0.62 0.16
13 INT255258 Binding of Rb1 and Tsp1 1 0.38 0.95 0.15
14 INT310263 Rb1 Negative_regulation of Gene_expression of Tnf 1 0.07 0.97 0.15
15 INT325056 Binding of E2f1 and Ang 1 0.06 1.3 0.12
16 INT226907 Binding of E2f1 and Nfkb1 1 0.14 0.6 0.12
17 INT238392 RB1 Regulation of E2F2 1 0.01 0.36 0.08
18 INT255256 Positive_regulation of Binding of Rb1 and Tsp1 1 0.50 0.48 0.08
19 INT76862 Dynll1 Positive_regulation of Rb1 1 0.37 0.1 0.06
20 INT257867 Negative_regulation of Eif4e Positive_regulation of Rb1 1 0.05 0.54 0.06
21 INT197617 Binding of S100a6 and Rb1 1 0.03 0 0.06
22 INT298806 Binding of Hdac3 and Rb1 1 0.02 0.77 0.05
23 INT169962 Binding of Rb1 and E2f4 1 0.25 0.56 0.04
24 INT333848 Binding of Ccna1 and Rb1 1 0.04 0.48 0.04
25 INT197587 Ppt1 Positive_regulation of Rb1 1 0.18 0 0.03
26 INT197593 Dlat Positive_regulation of Rb1 1 0.04 0 0.03
27 INT94157 CDCP1 Negative_regulation of RB1 1 0.02 0.92 0.03
28 INT94159 Positive_regulation of CDK1 Negative_regulation of RB1 1 0.45 0.93 0.03
29 INT94158 CDK1 Negative_regulation of RB1 1 0.41 0.92 0.03
30 INT238393 Binding of E2F2 and RB1 3 0.04 0.24 0
31 INT225610 Ncoa6 Regulation of Rb1 1 0.03 0.21 0
32 INT196954 Binding of Atp8a1 and E2f1 1 0.40 0.49 0
33 INT301244 Rb1 Regulation of Hbp1 1 0.03 0.75 0
34 INT337402 LEF1 Positive_regulation of E2F1 1 0.11 0 0
35 INT337270 E2F1 Positive_regulation of Transcription of THBS1 1 0.67 0.19 0
36 INT345505 E2f1 Positive_regulation of PMAIP1 1 0.18 0.62 0
37 INT334322 Binding of RB1 and TP53 1 0.34 2 0
38 INT337268 E2F1 Regulation of Transcription of THBS1 1 0.44 0 0
39 INT337274 E2F1 Regulation of THBS1 1 0.44 0 0
40 INT337269 Binding of E2F1 and Positive_regulation of Gene_expression of THBS1 1 0.45 0.21 0
41 INT273774 Binding of GPER and RB1 1 0.01 0.45 0
42 INT305542 Binding of Rb1 and Trp53 1 0.00 0.9 0
43 INT169963 Positive_regulation of Binding of Rb1 and Rbl2 1 0.33 0.1 0
44 INT306825 Positive_regulation of Binding of E2F2 and RB1 1 0.04 0.05 0
45 INT196959 Hmga2 Positive_regulation of Localization of E2f1 1 0.54 0.24 0
46 INT196958 Phosphorylation of Rb1 Positive_regulation of Localization of E2f1 1 0.45 0.44 0
47 INT169959 Binding of Rb1 and Rbl2 1 0.26 0.1 0
48 INT337264 Binding of E2F1 and THBS1 1 0.47 0.78 0
49 INT333448 RB1 Positive_regulation of TFDP1 1 0.05 0 0
50 INT330696 Phosphorylation of RB1 Positive_regulation of Gene_expression of E2F2 1 0.01 1 0
51 INT337273 E2F1 Regulation of Gene_expression of THBS1 1 0.60 0 0
52 INT196940 Positive_regulation of Hmga2 Positive_regulation of E2f1 1 0.50 0.47 0
53 INT196955 Binding of E2f1 and Rb1 1 0.36 1 0
54 INT217149 MIR20A Regulation of Gene_expression of E2F1 1 0.19 0.86 0
55 INT330698 PCNA Regulation of RB1 1 0.00 0.3 0
56 INT196946 Binding of E2f1 and Hdac1 1 0.26 0.65 0
57 INT176284 Binding of E2f1 and p53-ps 1 0.02 0.28 0
58 INT337266 E2F1 Positive_regulation of Gene_expression of THBS1 1 0.67 0.21 0
59 INT337491 Binding of E2F1 and Tcf7 1 0.19 0 0
60 INT337401 Binding of E2F1 and HDAC1 1 0.07 0 0
61 INT337261 Binding of E2F1 and PRB1 1 0.17 1.19 0
62 INT196943 E2f1 Negative_regulation of Rb1 1 0.42 0.44 0
63 INT196961 Binding of Hmga2 and Rb1 1 0.48 6.47 0
64 INT337265 Negative_regulation of E2F1 Positive_regulation of THBS1 1 0.42 0 0
65 INT247427 CDKN2A Negative_regulation of Negative_regulation of RB1 1 0.07 1.16 0
66 INT337272 E2F1 Positive_regulation of THBS1 1 0.49 1.27 0
67 INT337267 THBS1 Positive_regulation of E2F1 1 0.49 0.05 0
68 INT196950 Binding of Rb1 and E2f2 1 0.01 0.6 0
69 INT196947 Binding of Rb1 and Positive_regulation of Hmga2 1 0.50 0.3 0
70 INT196951 Hmga2 Positive_regulation of E2f1 1 0.50 0.98 0
71 INT196941 Hdac1 Negative_regulation of Rb1 1 0.27 0.44 0
72 INT196945 Rb1 Negative_regulation of Transcription of E2f1 1 0.42 0.35 0
73 INT196944 Binding of Rb1 and Hdac1 1 0.24 0.4 0
74 INT196942 Binding of E2f1 and Hmga2 1 0.39 0.87 0
75 INT217147 MIR17 Regulation of Gene_expression of E2F1 1 0.20 0.85 0
76 INT305336 TP53 Negative_regulation of Phosphorylation of RB1 1 0.29 0.96 0
77 INT147144 E2F1 Positive_regulation of Transcription of TYMS 1 0.26 0 0
78 INT196953 Hmga2 Negative_regulation of Rb1 1 0.59 0.35 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of transcription involved in G1/S phase of mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of transcription involved in G1/S phase of mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21
2 INT29929 Gene_expression of Rb1 20 0.69 5.81 3.1
3 INT54938 Regulation of Rb1 6 0.44 4.41 2.69
4 INT57970 Positive_regulation of Rb1 17 0.67 7.03 2.36
5 INT73266 Gene_expression of RB1 50 0.70 29.09 2.31
6 INT163283 Gene_expression of E2F1 21 0.71 3.77 2.26
7 INT57971 Regulation of Rb1 5 0.41 2.36 1.66
8 INT94169 Negative_regulation of Phosphorylation of RB1 16 0.41 8.87 1.57
9 INT169907 Gene_expression of Rb1 25 0.60 21.95 1.32
10 INT63905 Regulation of RB1 13 0.62 12.67 1.28
11 INT306868 Positive_regulation of Gene_expression of E2F1 6 0.46 1.01 1.28
12 INT22815 Positive_regulation of RB1 20 0.49 14.58 1.26
13 INT41124 Negative_regulation of Rb1 11 0.44 3.17 1.22
14 INT118368 Positive_regulation of E2F1 10 0.69 0.8 1.13
15 INT126993 Binding of E2F1 5 0.44 1.39 1.12
16 INT174188 Positive_regulation of Gene_expression of RB1 9 0.45 6.22 0.94
17 INT169911 Phosphorylation of Rb1 35 0.73 18.58 0.79
18 INT126990 Positive_regulation of Binding of E2F1 4 0.58 0 0.79
19 INT41123 Positive_regulation of Rb1 12 0.44 3.03 0.73
20 INT169931 Localization of Rb1 6 0.70 4.79 0.65
21 INT306839 Negative_regulation of Gene_expression of E2F1 2 0.39 0.24 0.61
22 INT62266 Phosphorylation of Rb1 4 0.71 2.68 0.54
23 INT118369 Regulation of E2F1 5 0.56 3.51 0.52
24 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51
25 INT163038 Binding of E2f1 2 0.44 0.08 0.5
26 INT93397 Negative_regulation of Phosphorylation of Rb1 1 0.51 0.32 0.48
27 INT163035 Gene_expression of E2f1 8 0.71 2.68 0.47
28 INT163037 Positive_regulation of Gene_expression of E2f1 1 0.11 0 0.44
29 INT163036 Positive_regulation of E2f1 1 0.11 0 0.44
30 INT169952 Gene_expression of E2f1 12 0.64 4.35 0.43
31 INT194993 Binding of RB1 15 0.37 10.96 0.4
32 INT196916 Negative_regulation of Rb1 13 0.42 14.29 0.4
33 INT172626 Localization of E2F1 3 0.78 1.97 0.4
34 INT41125 Positive_regulation of Localization of Rb1 2 0.38 0.78 0.39
35 INT41126 Localization of Rb1 2 0.61 0.78 0.39
36 INT147152 Negative_regulation of E2F1 6 0.56 0.89 0.38
37 INT196925 Positive_regulation of Gene_expression of Rb1 4 0.45 3.16 0.33
38 INT169918 Negative_regulation of Phosphorylation of Rb1 8 0.37 6.64 0.32
39 INT197599 Transcription of Rb1 4 0.63 0.87 0.3
40 INT126991 Regulation of Binding of E2F1 1 0.23 0 0.28
41 INT126992 Positive_regulation of Regulation of E2F1 1 0.58 0 0.28
42 INT207163 Regulation of Gene_expression of Rb1 3 0.39 1.08 0.22
43 INT196920 Transcription of E2f1 4 0.68 2.65 0.21
44 INT196929 Positive_regulation of E2f1 10 0.66 4.29 0.19
45 INT293677 Transcription of RB1 1 0.62 0.8 0.18
46 INT169930 Binding of Rb1 15 0.43 5.91 0.16
47 INT94168 Positive_regulation of Phosphorylation of RB1 12 0.60 6.6 0.15
48 INT325053 Regulation of E2f1 1 0.19 2.02 0.15
49 INT197627 Localization of RB1 3 0.69 4.16 0.13
50 INT169928 Positive_regulation of Gene_expression of E2f1 3 0.48 1.29 0.13
51 INT314724 Regulation of Localization of RB1 1 0.15 1.25 0.13
52 INT190563 Regulation of Binding of Rb1 1 0.08 0.7 0.13
53 INT169940 Positive_regulation of Localization of Rb1 2 0.61 1.74 0.11
54 INT257732 Regulation of Positive_regulation of RB1 2 0.39 2.35 0.09
55 INT62267 Negative_regulation of Gene_expression of Rb1 1 0.12 0.82 0.07
56 INT163282 Negative_regulation of Phosphorylation of E2F1 1 0.35 0.33 0.07
57 INT62265 Negative_regulation of Positive_regulation of Rb1 1 0.12 0.85 0.07
58 INT163288 Phosphorylation of E2F1 1 0.66 0.33 0.07
59 INT197606 Binding of Rb1 2 0.28 0.14 0.06
60 INT169929 Negative_regulation of E2f1 12 0.41 3.03 0.04
61 INT245909 Positive_regulation of Transcription of Rb1 1 0.05 0.49 0.04
62 INT196912 Binding of E2f1 6 0.46 2.3 0.03
63 INT236701 Negative_regulation of Gene_expression of Rb1 4 0.10 4.55 0.03
64 INT169945 Positive_regulation of Phosphorylation of Rb1 4 0.41 1.75 0.03
65 INT298776 Regulation of Phosphorylation of Rb1 1 0.04 0.39 0.03
66 INT174197 Negative_regulation of Gene_expression of RB1 4 0.47 4.25 0
67 INT348463 Protein_catabolism of RB1 2 0.11 2.22 0
68 INT225170 Regulation of Phosphorylation of RB1 2 0.36 1.12 0
69 INT225167 Negative_regulation of Binding of RB1 2 0.34 1.25 0
70 INT247431 Positive_regulation of Negative_regulation of RB1 2 0.45 2.58 0
71 INT196935 Negative_regulation of Binding of Rb1 1 0.38 0.24 0
72 INT197596 Negative_regulation of Transcription of Rb1 1 0.38 0.22 0
73 INT217169 Positive_regulation of Transcription of E2F1 1 0.46 0.79 0
74 INT293681 Positive_regulation of Positive_regulation of RB1 1 0.39 0.27 0
75 INT197608 Positive_regulation of Gene_expression of Rb1 1 0.44 0 0
76 INT258060 Positive_regulation of Protein_catabolism of E2F1 1 0.08 0.52 0
77 INT169927 Protein_catabolism of E2f1 1 0.44 0.12 0
78 INT293672 Positive_regulation of Transcription of RB1 1 0.45 0.4 0
79 INT196911 Phosphorylation of E2f1 1 0.77 0.39 0
80 INT196926 Localization of E2f1 1 0.76 1.17 0
81 INT196910 Positive_regulation of Binding of Rb1 1 0.45 0.81 0
82 INT273783 Regulation of Gene_expression of RB1 1 0.29 0.67 0
83 INT196922 Positive_regulation of Positive_regulation of E2f1 1 0.44 0.75 0
84 INT196933 Positive_regulation of Binding of E2f1 1 0.44 0.31 0
85 INT196924 Negative_regulation of Gene_expression of E2f1 1 0.41 0.43 0
86 INT258047 Negative_regulation of Protein_catabolism of E2F1 1 0.07 0.52 0
87 INT204055 Positive_regulation of Negative_regulation of Rb1 1 0.03 0.55 0
88 INT217233 Transcription of E2F1 1 0.48 0.78 0
89 INT196930 Regulation of E2f1 1 0.43 0.23 0
90 INT147150 Negative_regulation of Negative_regulation of E2F1 1 0.41 0 0
91 INT258062 Protein_catabolism of E2F1 1 0.11 1.05 0
92 INT337280 Regulation of Gene_expression of E2F1 1 0.41 0.16 0
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