GO:0072108

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Name positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
Categary Process
Go Slim No
Go Link GO:0072108
Unique Molecular Interactions 164
Total Molecular Interactions 224
Total Single Events 971
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
2 INT180774 Gdnf Positive_regulation of Trpv1 1 0.33 2.43 4.37
3 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06
4 INT103330 Ngf Positive_regulation of Gdnf 2 0.28 1.27 2.45
5 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42
6 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
7 INT108129 GDNF Regulation of Gene_expression of GRHL3 1 0.21 0.39 1.71
8 INT180812 Gdnf Positive_regulation of Gene_expression of Sorbs1 1 0.02 0.83 1.61
9 INT180811 Gdnf Positive_regulation of Regulation of Sorbs1 1 0.01 0.83 1.61
10 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
11 INT180790 Gdnf Regulation of Localization of Trpv1 1 0.15 1.21 1.43
12 INT83197 Binding of Ntrk1 and Gdnf 1 0.01 1.05 1.36
13 INT180802 Gdnf Positive_regulation of Sorbs1 1 0.02 0.98 1.34
14 INT180764 Calca Regulation of Positive_regulation of Gdnf 1 0.21 0 1.32
15 INT242605 Gdnf Positive_regulation of Trpv1 1 0.26 0.17 1.3
16 INT148435 Binding of Bdnf and Gdnf 2 0.35 1.9 1.17
17 INT180814 Binding of Ret and Gdnf 1 0.01 1.31 1.17
18 INT242625 Gdnf Positive_regulation of Pax3 1 0.01 0.34 1.15
19 INT142413 Oprm1 Positive_regulation of Gdnf 1 0.19 0.29 1.09
20 INT8416 LIF Regulation of TAC1 1 0.13 0.36 1.04
21 INT8415 LIF Regulation of VIP 1 0.13 0.36 1.04
22 INT56743 LIF Positive_regulation of Cck 1 0.08 0.18 1.02
23 INT180770 Gdnf Positive_regulation of Zbtb38 1 0.00 0.27 0.99
24 INT56742 LIF Positive_regulation of Chat 1 0.02 0.2 0.98
25 INT147504 Binding of Ncam1 and Gdnf 1 0.31 0.87 0.98
26 INT180780 Ngf Regulation of Gdnf 1 0.22 0.28 0.96
27 INT180803 Sorbs1 Regulation of Gdnf 1 0.01 0.28 0.95
28 INT180787 Calca Regulation of Gdnf 1 0.18 0.28 0.95
29 INT147505 Binding of Ret and Gdnf 1 0.27 0.81 0.92
30 INT242621 Gdnf Positive_regulation of Gene_expression of Scn11a 1 0.05 0.12 0.88
31 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87
32 INT108128 GDNF Regulation of Localization of GRHL3 1 0.24 0.18 0.83
33 INT98479 Lif Regulation of Gene_expression of Grin1 1 0.04 0.35 0.82
34 INT103331 Ngf Positive_regulation of Gdnf 1 0.01 0.57 0.8
35 INT103334 Gdnf Regulation of Gene_expression of TRPV1 1 0.02 0.53 0.77
36 INT103333 Gdnf Regulation of TRPV1 1 0.02 0.53 0.77
37 INT149597 Lif Regulation of Regulation of Gal 1 0.30 0.69 0.73
38 INT180773 Calca Regulation of Binding of Gdnf 1 0.18 0.15 0.72
39 INT180783 Binding of Gdnf and Man2a2 1 0.00 0.52 0.71
40 INT180775 Binding of Gdnf and Gfra1 1 0.06 0.52 0.71
41 INT102121 Gdnf Regulation of Gene_expression of Cnr1 1 0.45 0.42 0.71
42 INT144367 Gdnf Negative_regulation of Positive_regulation of Th 1 0.11 0.77 0.7
43 INT149596 Lif Negative_regulation of Negative_regulation of Gal 1 0.10 0.5 0.7
44 INT82267 Lif Regulation of Gene_expression of Gal 1 0.40 2.76 0.62
45 INT122777 Gdnf Negative_regulation of Gene_expression of Trpv1 1 0.36 0.8 0.62
46 INT149595 Lif Negative_regulation of Negative_regulation of Trpv1 1 0.34 0.44 0.61
47 INT122774 Gdnf Negative_regulation of Positive_regulation of Trpv1 1 0.32 0.78 0.61
48 INT242584 Gdnf Regulation of Gene_expression of Qrfp 1 0.00 0.09 0.58
49 INT91267 Gdnf Negative_regulation of Gdnf 1 0.05 0.81 0.58
50 INT8440 Cntf Regulation of LIF 1 0.33 0.18 0.52
51 INT242598 Binding of Gdnf and Gfra2 4 0.16 0.38 0.51
52 INT242614 Binding of Gdnf and Gfra1 1 0.03 0 0.51
53 INT356279 Gdnf Regulation of Positive_regulation of Mapk1 1 0.03 0.76 0.5
54 INT98117 Gdnf Regulation of SCN11A 1 0.05 0.39 0.5
55 INT242597 Gene_expression of Gdnf Negative_regulation of Trpv1 1 0.27 0.08 0.5
56 INT98116 Gdnf Regulation of SCN10A 1 0.03 0.39 0.5
57 INT242638 Binding of BDNF and Gdnf 1 0.29 0 0.49
58 INT242600 Binding of Gdnf and Gopc 1 0.06 0 0.49
59 INT98480 Lif Positive_regulation of Pnoc 1 0.18 0.2 0.49
60 INT165582 Binding of Bdnf and Gdnf 1 0.36 0.47 0.49
61 INT242604 Gdnf Regulation of Gene_expression of Trpv1 1 0.17 0.36 0.48
62 INT98484 Lif Regulation of Gene_expression of Gal 1 0.04 0.16 0.47
63 INT98482 Lif Positive_regulation of Gene_expression of Pnoc 1 0.16 0.17 0.46
64 INT98119 Gdnf Regulation of SCN10A 1 0.01 0.34 0.45
65 INT98118 Gdnf Regulation of SCN11A 1 0.01 0.34 0.45
66 INT98481 Lif Regulation of Regulation of Oprl1 1 0.04 0.16 0.45
67 INT104459 Gdnf Regulation of Ngf 1 0.26 0.56 0.45
68 INT188205 OSM Regulation of LIF 1 0.09 1.12 0.43
69 INT127074 Gdnf Regulation of Gene_expression of Jun 1 0.10 0.28 0.43
70 INT188207 LIF Regulation of IL6 1 0.17 1.12 0.43
71 INT127072 Gdnf Regulation of Gene_expression of Fos 1 0.38 0.28 0.43
72 INT127077 Gdnf Positive_regulation of Gene_expression of IER3 1 0.02 0.26 0.42
73 INT127079 Gene_expression of Gdnf Positive_regulation of Gene_expression of IER3 1 0.02 0.26 0.42
74 INT148436 Binding of Gdnf and Ngf 1 0.35 1.14 0.4
75 INT91719 Binding of BDNF and LIF 1 0.09 1.65 0.38
76 INT78627 Gdnf Negative_regulation of Negative_regulation of P2rx3 1 0.00 0.42 0.38
77 INT140869 Binding of Gdnf and Trib3 1 0.04 0.15 0.37
78 INT309366 Pax2 Negative_regulation of Transcription of Slc6a5 1 0.03 0 0.31
79 INT309369 Ptf1a Positive_regulation of Pax2 1 0.10 0 0.3
80 INT356278 Gdnf Positive_regulation of Mapk1 1 0.05 0.17 0.3
81 INT356282 Gdnf Positive_regulation of Trib3 1 0.00 0.17 0.3
82 INT180788 Gdnf Regulation of Trpv1 1 0.13 0.2 0.28
83 INT277434 Cd5 Regulation of Gdnf 1 0.01 0 0.21
84 INT82268 Lif Regulation of Gene_expression of Iapp 1 0.06 0.9 0.2
85 INT222426 Lif Positive_regulation of Localization of Pomc 1 0.02 0.75 0.17
86 INT32211 POMC Positive_regulation of Gene_expression of Lif 1 0.01 0.61 0.15
87 INT326385 Mtdh Regulation of Gdnf 1 0.00 0.41 0.14
88 INT193551 Mtpn Positive_regulation of Gene_expression of Gdnf 1 0.02 0.34 0.13
89 INT193552 Gdnf Positive_regulation of Gene_expression of Mtpn 1 0.02 0.34 0.13
90 INT277433 Wibg Positive_regulation of Gdnf 1 0.01 0.6 0.13
91 INT277430 Wibg Positive_regulation of Gene_expression of Gdnf 1 0.01 0.6 0.13
92 INT193548 Gdnf Positive_regulation of Ephb1 1 0.40 0.34 0.13
93 INT141281 ARTN Regulation of Gdnf 1 0.48 0.32 0.12
94 INT188197 LIF Positive_regulation of STAT3 1 0.35 0.27 0.12
95 INT141279 Nrtn Regulation of Gdnf 1 0.14 0.32 0.12
96 INT141280 PSPN Regulation of Gdnf 1 0.48 0.32 0.12
97 INT96518 Regulation of Gdnf Positive_regulation of Ret 1 0.00 0.23 0.11
98 INT309371 Lhx1 Positive_regulation of Gene_expression of Pax2 1 0.08 0.07 0.11
99 INT309372 Lhx5 Positive_regulation of Gene_expression of Pax2 1 0.09 0.07 0.11
100 INT294440 KLK4 Negative_regulation of LIF 1 0.00 0 0.1
101 INT213554 Gdnf Regulation of Bdnf 1 0.13 0.14 0.1
102 INT213550 Bdnf Regulation of Gdnf 1 0.13 0.14 0.1
103 INT96519 Gdnf Positive_regulation of Ret 1 0.00 0.22 0.1
104 INT356275 Gdnf Positive_regulation of Phosphorylation of Mapk1 1 0.05 0.21 0.09
105 INT242594 Binding of Gdnf and Ret 1 0.21 0 0.08
106 INT355019 Lif Positive_regulation of JAK1 1 0.00 0.69 0.08
107 INT326381 Binding of Gdnf and Pcdhb16 1 0.00 0.3 0.08
108 INT326382 Binding of Gdnf and Ncam1 1 0.01 0.3 0.08
109 INT299539 Lif Positive_regulation of Phosphorylation of Stat3 1 0.08 0 0.08
110 INT355020 Lif Positive_regulation of SOAT1 1 0.02 0.7 0.08
111 INT355010 Lif Positive_regulation of Il6st 1 0.02 0.69 0.08
112 INT277431 Positive_regulation of Grm3 Positive_regulation of Gene_expression of Gdnf 1 0.18 0 0.07
113 INT299548 Binding of TGFB1 and Lif 1 0.02 0 0.07
114 INT12987 LIF Regulation of Localization of Prl 1 0.09 0 0.07
115 INT299535 Binding of Egf and Lif 1 0.07 0 0.07
116 INT277432 Ptpn2 Positive_regulation of Gdnf 1 0.29 1.41 0.06
117 INT268652 Binding of CLDN4 and LIF 1 0.35 0.44 0.04
118 INT79985 Gdnf Negative_regulation of Negative_regulation of GAD1 1 0.04 0.46 0.04
119 INT79986 Gdnf Negative_regulation of Gene_expression of GAD1 1 0.03 0.46 0.04
120 INT261388 Nsdhl Regulation of Lif 1 0.08 0.67 0.04
121 INT261377 Nsdhl Positive_regulation of Lif 1 0.08 0.6 0.03
122 INT242601 Gdnf Positive_regulation of Chat 1 0.29 0.15 0.03
123 INT266075 LIF Regulation of Gene_expression of PAEP 1 0.19 0.43 0.03
124 INT266070 LIF Regulation of Gene_expression of PAPPA 1 0.35 0.49 0.03
125 INT277429 Ptpn2 Regulation of Gdnf 1 0.34 0.47 0.03
126 INT266072 LGALS1 Regulation of Gene_expression of LIF 1 0.17 0.43 0.03
127 INT266067 PAPPA Regulation of Gene_expression of LIF 1 0.35 0.49 0.03
128 INT277427 Ptpn2 Positive_regulation of Gene_expression of Gdnf 1 0.32 0.47 0.03
129 INT266076 LIF Regulation of Gene_expression of LGALS1 1 0.17 0.43 0.03
130 INT277428 Positive_regulation of Ptpn2 Positive_regulation of Gdnf 1 0.29 0.47 0.03
131 INT66341 LIF Positive_regulation of Gene_expression of FOS 1 0.11 1.07 0
132 INT66339 LIF Positive_regulation of Phosphorylation of CLIP2 1 0.45 1.57 0
133 INT268651 NUPL2 Positive_regulation of Gene_expression of LIF 1 0.66 0.07 0
134 INT244839 Lbx1 Positive_regulation of Pax2 1 0.39 0 0
135 INT115368 Binding of GDNF and RAPGEF5 1 0.32 0 0
136 INT342043 Binding of Gdnf and Unc5a 1 0.20 0.78 0
137 INT252888 Binding of SLC5A5 and PAX8 1 0.02 0.22 0
138 INT240271 Binding of GDNF and RET 1 0.09 1.04 0
139 INT66342 LIF Positive_regulation of Phosphorylation of CLIP1 1 0.60 1.57 0
140 INT236171 Binding of LIF and Hmgcr 1 0.02 0 0
141 INT297691 Binding of Fut1 and Pax2 1 0.03 0 0
142 INT66353 LIF Regulation of Ctf2p 1 0.02 0.47 0
143 INT342038 Binding of Gdnf and Ntn1 1 0.01 0.78 0
144 INT356271 Gdnf Positive_regulation of Positive_regulation of Mapk1 1 0.05 0.25 0
145 INT66340 LIF Positive_regulation of C1orf61 1 0.12 0.52 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT74389 Gene_expression of Gdnf 131 0.78 58.52 57.06
2 INT48890 Gene_expression of Gdnf 91 0.77 28.62 31.49
3 INT77793 Positive_regulation of Gdnf 54 0.70 23.76 25.08
4 INT102897 Positive_regulation of Gene_expression of Gdnf 34 0.69 11.13 13.28
5 INT79981 Positive_regulation of Gene_expression of Gdnf 27 0.70 12.49 10.77
6 INT82950 Positive_regulation of Gdnf 36 0.51 11.72 10.5
7 INT85844 Regulation of Gdnf 18 0.50 11.08 10.43
8 INT21952 Gene_expression of GDNF 42 0.78 20.32 9.62
9 INT98111 Negative_regulation of Gdnf 12 0.59 10.85 9.29
10 INT77795 Localization of Gdnf 26 0.81 6.29 8.55
11 INT77794 Binding of Gdnf 15 0.48 8.38 8.22
12 INT92003 Positive_regulation of Transcription of Gdnf 10 0.66 5.54 7.84
13 INT87546 Transcription of Gdnf 15 0.71 7.49 7.76
14 INT2111 Gene_expression of LIF 34 0.77 16.82 6.76
15 INT92001 Regulation of Gene_expression of Gdnf 12 0.62 6.62 6.65
16 INT87548 Negative_regulation of Gene_expression of Gdnf 9 0.54 5.67 5.94
17 INT115087 Negative_regulation of Gdnf 10 0.51 5.78 5.73
18 INT78626 Regulation of Gdnf 7 0.45 3.3 4.64
19 INT32208 Gene_expression of Lif 23 0.74 6.23 3.7
20 INT88008 Positive_regulation of Gene_expression of GDNF 14 0.70 8.9 3.61
21 INT78625 Regulation of Gene_expression of Gdnf 7 0.37 2.5 3.47
22 INT82265 Gene_expression of Lif 7 0.50 6.17 3.4
23 INT76240 Positive_regulation of Lif 6 0.69 6.04 3.13
24 INT209744 Transcription of Gdnf 5 0.67 1.36 2.84
25 INT144366 Negative_regulation of Positive_regulation of Gdnf 4 0.41 1.43 2.41
26 INT33895 Positive_regulation of LIF 9 0.67 2.47 2.34
27 INT98650 Positive_regulation of Localization of Gdnf 4 0.68 0.94 2.27
28 INT88006 Positive_regulation of GDNF 5 0.45 2.55 2.14
29 INT180801 Regulation of Binding of Gdnf 1 0.20 1.31 2.03
30 INT209745 Positive_regulation of Transcription of Gdnf 4 0.58 0.97 1.91
31 INT44027 Positive_regulation of Lif 7 0.40 2.76 1.9
32 INT93182 Binding of Gdnf 7 0.35 1.96 1.64
33 INT253751 Localization of Lif 3 0.73 3.94 1.58
34 INT98651 Regulation of Positive_regulation of Gdnf 3 0.44 0.97 1.58
35 INT21951 Negative_regulation of Gene_expression of GDNF 5 0.43 2.82 1.57
36 INT50437 Regulation of LIF 6 0.44 2.12 1.53
37 INT50436 Negative_regulation of Positive_regulation of LIF 1 0.37 0.33 1.42
38 INT87547 Negative_regulation of Transcription of Gdnf 1 0.58 1.24 1.4
39 INT34933 Positive_regulation of Gene_expression of LIF 6 0.67 3.41 1.38
40 INT108130 Localization of GDNF 3 0.74 1.36 1.38
41 INT98653 Negative_regulation of Localization of Gdnf 1 0.57 0.31 1.35
42 INT180795 Positive_regulation of Positive_regulation of Gdnf 2 0.29 0.1 1.07
43 INT108985 Negative_regulation of Regulation of Gdnf 1 0.43 1.11 1.04
44 INT149594 Positive_regulation of Gene_expression of Lif 2 0.47 0.89 1
45 INT102819 Regulation of Lif 8 0.53 2.05 0.87
46 INT98478 Negative_regulation of Lif 3 0.42 1.29 0.84
47 INT82262 Regulation of Lif 3 0.31 1.67 0.83
48 INT354449 Positive_regulation of Localization of Lif 1 0.33 1.24 0.83
49 INT121947 Negative_regulation of Positive_regulation of Gdnf 1 0.20 0.07 0.76
50 INT68794 Negative_regulation of LIF 6 0.41 1.38 0.7
51 INT236094 Localization of Gdnf 4 0.70 2.51 0.68
52 INT209746 Regulation of Positive_regulation of Gdnf 2 0.37 0.11 0.68
53 INT2109 Negative_regulation of Gene_expression of LIF 4 0.41 0.89 0.66
54 INT241673 Phosphorylation of GDNF 2 0.79 1.06 0.61
55 INT85138 Binding of GDNF 6 0.37 2.01 0.58
56 INT98112 Positive_regulation of Negative_regulation of Gdnf 1 0.05 0.44 0.57
57 INT216834 Localization of Lif 2 0.34 0.23 0.46
58 INT299516 Phosphorylation of Lif 1 0.26 0.56 0.46
59 INT127069 Regulation of Localization of Gdnf 1 0.34 0.46 0.46
60 INT2110 Localization of LIF 5 0.73 1.59 0.44
61 INT32207 Regulation of Gene_expression of Lif 3 0.19 1.01 0.42
62 INT148433 Negative_regulation of Binding of Gdnf 1 0.41 1.14 0.4
63 INT213507 Gene_expression of Pax2 10 0.67 1.41 0.34
64 INT88012 Regulation of Gene_expression of GDNF 2 0.43 0.48 0.31
65 INT299519 Binding of Lif 2 0.21 0.67 0.29
66 INT309354 Regulation of Pax2 1 0.10 0 0.29
67 INT309339 Negative_regulation of Localization of Pax2 1 0.15 0 0.28
68 INT242536 Negative_regulation of Gene_expression of Gdnf 1 0.30 0.06 0.28
69 INT188235 Phosphorylation of LIF 1 0.53 0.48 0.23
70 INT318610 Positive_regulation of Binding of Lif 1 0.28 0.67 0.19
71 INT188224 Regulation of Gene_expression of LIF 1 0.23 0.53 0.18
72 INT188216 Positive_regulation of Regulation of LIF 1 0.39 1.13 0.17
73 INT88007 Regulation of GDNF 2 0.34 0.82 0.16
74 INT338147 Negative_regulation of Gene_expression of Lif 1 0.38 0.29 0.15
75 INT216451 Negative_regulation of Lif 1 0.36 0.77 0.15
76 INT309352 Localization of Pax2 1 0.27 0 0.14
77 INT277419 Positive_regulation of Positive_regulation of Gdnf 1 0.47 0 0.12
78 INT88013 Transcription of GDNF 2 0.40 0.22 0.11
79 INT88011 Positive_regulation of Transcription of GDNF 1 0.35 0.22 0.11
80 INT333440 Protein_catabolism of Lif 1 0.23 0.2 0.08
81 INT277418 Regulation of Binding of Gdnf 1 0.42 0 0.08
82 INT245059 Localization of PAX8 1 0.51 1.43 0.08
83 INT216454 Binding of Lif 2 0.27 0.85 0.07
84 INT347981 Positive_regulation of Phosphorylation of Gdnf 1 0.11 0.79 0.07
85 INT347993 Regulation of Phosphorylation of Gdnf 1 0.10 0.87 0.07
86 INT347980 Phosphorylation of Gdnf 1 0.19 0.79 0.07
87 INT299524 Positive_regulation of Localization of Lif 1 0.21 0 0.06
88 INT244741 Positive_regulation of Gene_expression of Pax2 1 0.38 0 0.06
89 INT333439 Positive_regulation of Gene_expression of Lif 1 0.18 0.18 0.04
90 INT266088 Positive_regulation of Localization of LIF 1 0.34 0.45 0.03
91 INT66346 Binding of LIF 7 0.47 0.9 0
92 INT244782 Negative_regulation of Pax2 1 0.44 0 0
93 INT159329 Transcription of Lif 1 0.36 0.15 0
94 INT300189 Negative_regulation of Localization of Lif 1 0.41 0.47 0
95 INT268657 Regulation of Localization of LIF 1 0.38 0.07 0
96 INT213529 Negative_regulation of Gene_expression of Pax2 1 0.37 0.23 0
97 INT331205 Protein_catabolism of Gdnf 1 0.03 0.57 0
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