GO:0072372

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Name primary cilium
Categary Component
Go Slim No
Go Link GO:0072372
Unique Molecular Interactions 41
Total Molecular Interactions 54
Total Single Events 224
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for primary cilium. They are ordered first by their pain relevance and then by number of times they were reported for primary cilium. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT156622 Umod Regulation of Phosphorylation of Creb1 1 0.05 0.33 2.27
2 INT156623 Umod Regulation of Phosphorylation of Ephb1 1 0.05 0.33 2.27
3 INT75200 Umod Positive_regulation of Transcription of Psma4 1 0.02 1.04 0.92
4 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
5 INT297342 Binding of Gnb5 and Smo 1 0.02 1.67 0.34
6 INT66813 Umod Negative_regulation of POMC 1 0.03 0.42 0.26
7 INT196823 Adcy5 Positive_regulation of Prkaca 1 0.13 0 0.22
8 INT196822 Negative_regulation of Adcy5 Positive_regulation of Pde1a 1 0.01 0 0.19
9 INT196815 Adcy5 Positive_regulation of Pde1a 1 0.01 0 0.19
10 INT156057 UMOD Regulation of GABRG3 1 0.01 0.54 0.14
11 INT196811 Binding of Pde1a and Adcy5 1 0.01 0 0.14
12 INT13014 Avp Positive_regulation of Adcy5 1 0.00 0.07 0.13
13 INT345343 PTCH1 Regulation of Negative_regulation of SMO 1 0.09 2.3 0.13
14 INT156056 AKR1C1 Negative_regulation of UMOD 1 0.03 0.41 0.1
15 INT262751 Binding of PTCH1 and SMO 1 0.25 1.29 0.1
16 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
17 INT350010 Binding of IL6 and AHI1 1 0.01 0.29 0.06
18 INT340427 Positive_regulation of P2rx7 Positive_regulation of Regulation of Pkhd1 1 0.01 1 0.05
19 INT262757 SMO Positive_regulation of Regulation of GLI1 1 0.34 0.6 0.04
20 INT270458 Binding of Gli1 and Smo 1 0.00 0.65 0.04
21 INT283346 Binding of Srr and Kif3a 1 0.17 0 0
22 INT324347 Binding of UMOD and Scr 1 0.20 2.23 0
23 INT324342 UMOD Positive_regulation of Scr 1 0.17 1.29 0
24 INT324312 Binding of GATM and UMOD 1 0.02 1.62 0
25 INT205975 Binding of PTCH1 and Smo 1 0.02 0.72 0
26 INT324346 Regulation of UMOD Positive_regulation of Scr 1 0.10 1.31 0
27 INT205974 Smo Positive_regulation of GLI1 1 0.04 0.66 0
28 INT352525 SLC25A16 Negative_regulation of SMO 1 0.00 1.1 0
29 INT346596 Sh2d1b2 Negative_regulation of Umod 1 0.23 0 0
30 INT324305 Binding of CST3 and UMOD 1 0.05 3.22 0
31 INT324313 Binding of STC1 and UMOD 1 0.29 3.22 0
32 INT324311 Binding of UMOD and SHROOM3 1 0.29 1.62 0
33 INT324344 Positive_regulation of UMOD Regulation of Scr 1 0.24 0.29 0
34 INT286589 Binding of PKHD1 and Pkd2 1 0.09 0.52 0
35 INT205965 Binding of Ptch1 and Smo 1 0.03 0.72 0
36 INT324341 UMOD Regulation of Scr 1 0.21 0.29 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for primary cilium. They are ordered first by their pain relevance and then by number of times they were reported in primary cilium. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT75197 Gene_expression of Umod 3 0.75 2.48 4.75
2 INT14068 Positive_regulation of Umod 4 0.49 2.3 3.53
3 INT37130 Negative_regulation of Umod 5 0.41 1.81 2.91
4 INT135134 Positive_regulation of Gene_expression of Umod 2 0.49 1.13 1.91
5 INT62972 Gene_expression of Adcy5 3 0.67 0.23 1.72
6 INT13013 Positive_regulation of Adcy5 4 0.67 0.3 1.49
7 INT12034 Positive_regulation of Umod 6 0.69 3.25 1.33
8 INT61429 Gene_expression of Adcy5 6 0.60 1.49 1.27
9 INT65190 Regulation of Umod 2 0.44 0.51 1.26
10 INT183068 Gene_expression of SMO 2 0.17 0.27 1.2
11 INT11266 Positive_regulation of UMOD 2 0.43 1.25 1.16
12 INT196743 Binding of Adcy5 1 0.25 0 1.04
13 INT150779 Regulation of Gene_expression of Umod 1 0.44 0.14 1.01
14 INT51244 Gene_expression of Umod 7 0.60 2.03 0.95
15 INT149962 Positive_regulation of Positive_regulation of Umod 1 0.49 0.76 0.94
16 INT75194 Positive_regulation of Negative_regulation of Umod 1 0.49 1.05 0.91
17 INT59884 Gene_expression of UMOD 4 0.78 2.32 0.82
18 INT196762 Negative_regulation of Adcy5 5 0.39 1.49 0.8
19 INT270447 Binding of Smo 2 0.07 2.61 0.78
20 INT196734 Positive_regulation of Adcy5 1 0.35 0 0.75
21 INT62973 Positive_regulation of Gene_expression of Adcy5 1 0.05 0.16 0.74
22 INT174517 Localization of AHI1 2 0.24 1.62 0.68
23 INT95337 Negative_regulation of AHI1 2 0.02 0.75 0.68
24 INT205957 Negative_regulation of Smo 4 0.08 2.57 0.6
25 INT341654 Localization of UMOD 1 0.73 2.2 0.57
26 INT35699 Binding of Umod 3 0.41 2.3 0.46
27 INT51242 Localization of Umod 3 0.80 0.96 0.38
28 INT324332 Binding of UMOD 7 0.41 7.07 0.35
29 INT330611 Negative_regulation of Gene_expression of Umod 2 0.45 0.39 0.35
30 INT156054 Binding of Umod 1 0.30 0.35 0.35
31 INT164337 Localization of Adcy5 1 0.38 0 0.33
32 INT164338 Regulation of Adcy5 1 0.14 0 0.33
33 INT356400 Transcription of Smo 1 0.02 0.05 0.3
34 INT277474 Positive_regulation of Gene_expression of SMO 1 0.11 0 0.29
35 INT216120 Negative_regulation of SMO 2 0.49 3.05 0.27
36 INT196792 Binding of Adcy5 1 0.35 0 0.25
37 INT63041 Positive_regulation of Gene_expression of Umod 2 0.46 0.1 0.19
38 INT156053 Phosphorylation of Umod 1 0.67 0.1 0.19
39 INT51243 Negative_regulation of Umod 3 0.33 0.52 0.18
40 INT296875 Positive_regulation of AHI1 2 0.15 3.53 0.16
41 INT251975 Positive_regulation of Pkhd1 5 0.10 8.98 0.15
42 INT76794 Gene_expression of AHI1 3 0.04 1.69 0.14
43 INT3293 Negative_regulation of UMOD 1 0.35 0.36 0.11
44 INT196776 Negative_regulation of Negative_regulation of Adcy5 1 0.22 0 0.11
45 INT48325 Localization of Umod 2 0.58 0.39 0.09
46 INT76793 Regulation of Gene_expression of AHI1 1 0.00 0.13 0.07
47 INT145889 Positive_regulation of Gene_expression of AHI1 1 0.01 0.47 0.07
48 INT345344 Regulation of SMO 1 0.23 1.07 0.06
49 INT196788 Positive_regulation of Binding of Adcy5 1 0.22 0 0.05
50 INT262772 Binding of SMO 1 0.27 0.59 0.05
51 INT340406 Regulation of Pkhd1 1 0.01 0.99 0.05
52 INT262777 Localization of SMO 1 0.59 0.6 0.04
53 INT286581 Gene_expression of PKHD1 1 0.24 0.19 0.03
54 INT283314 Localization of Kif3a 1 0.69 0 0.03
55 INT340405 Gene_expression of Pkhd1 1 0.03 1.14 0.03
56 INT286580 Positive_regulation of Gene_expression of PKHD1 1 0.16 0.1 0.03
57 INT292996 Binding of Pkhd1 3 0.07 3.12 0
58 INT330613 Regulation of Gene_expression of Umod 2 0.21 0.07 0
59 INT252242 Gene_expression of Smo 1 0.01 0.23 0
60 INT283316 Gene_expression of Kif3a 1 0.55 0 0
61 INT286588 Positive_regulation of Localization of PKHD1 1 0.16 0.79 0
62 INT286576 Binding of PKHD1 1 0.12 0.63 0
63 INT283315 Positive_regulation of Kif3a 1 0.46 0 0
64 INT283328 Binding of Kif3a 1 0.34 0 0
65 INT205956 Localization of Smo 1 0.06 0.71 0
66 INT286584 Positive_regulation of PKHD1 1 0.13 1.01 0
67 INT286579 Localization of PKHD1 1 0.24 0.79 0
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