GO:0072593

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Name reactive oxygen species metabolic process
Categary Process
Go Slim No
Go Link GO:0072593
Unique Molecular Interactions 398
Total Molecular Interactions 497
Total Single Events 5156
Pain Genes Associated 23

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for reactive oxygen species metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for reactive oxygen species metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
2 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
3 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
4 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
5 INT285561 Il23a Positive_regulation of Gene_expression of Il22 2 0.06 2.45 0.93
6 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
7 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
8 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
9 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
10 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
11 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
12 INT205706 P2rx7 Regulation of Gene_expression of Il18 1 0.21 1.35 0.7
13 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
14 INT246335 Fig4 Regulation of Localization of P2rx7 1 0.01 0 0.67
15 INT205702 P2rx7 Regulation of Gene_expression of Il1 1 0.04 1.38 0.67
16 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
17 INT316674 Binding of CRP and SFTPD 1 0.16 2.02 0.59
18 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 0.07 1.42 0.58
19 INT308174 Binding of TNF and P2rx7 1 0.02 0.84 0.56
20 INT226517 Binding of IL19 and Il20ra 1 0.00 0.69 0.53
21 INT185490 Atp5o Negative_regulation of Gene_expression of P2rx7 1 0.01 0.87 0.53
22 INT216941 P2rx7 Regulation of Ryr1 1 0.01 0.55 0.52
23 INT278122 Negative_regulation of P2rx7 Negative_regulation of Binding of P2RX7 1 0.03 0 0.51
24 INT228449 PMAIP1 Negative_regulation of Fgf2 1 0.00 0.07 0.49
25 INT228448 PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49
26 INT228447 Negative_regulation of PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49
27 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
28 INT300544 Il22 Positive_regulation of Gene_expression of Mcpt1 1 0.02 1.15 0.47
29 INT306731 Il22 Positive_regulation of Gene_expression of Il2 1 0.12 1.07 0.46
30 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
31 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
32 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
33 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
34 INT169859 P2rx7 Regulation of Gene_expression of Grin1 1 0.17 0 0.43
35 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
36 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
37 INT332248 Ccl2 Positive_regulation of Ctgf 1 0.04 1.13 0.42
38 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
39 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
40 INT316675 Binding of CALR and SFTPD 1 0.35 0.96 0.37
41 INT316672 Binding of LRP1 and SFTPD 1 0.35 0.96 0.37
42 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
43 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
44 INT205704 P2rx7 Regulation of Localization of Il18 1 0.09 0.67 0.35
45 INT228446 PMAIP1 Regulation of Transcription of Mtpn 1 0.00 0 0.34
46 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
47 INT205713 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of IL8 1 0.03 0.77 0.33
48 INT217025 P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
49 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
50 INT316676 Binding of CRX and SFTPD 1 0.05 0.65 0.33
51 INT217024 Regulation of P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
52 INT205703 P2rx7 Regulation of Positive_regulation of Casp1 1 0.11 0.66 0.33
53 INT205711 P2rx7 Regulation of Localization of IL8 1 0.02 0.92 0.33
54 INT316488 Il22 Positive_regulation of Il10 1 0.29 0.63 0.32
55 INT145682 Binding of P2rx4 and P2rx7 2 0.25 0.36 0.31
56 INT258763 Binding of Drd5 and ADHD1 1 0.07 1.11 0.31
57 INT309366 Pax2 Negative_regulation of Transcription of Slc6a5 1 0.03 0 0.31
58 INT316487 Il22 Regulation of Il22ra1 1 0.12 0.61 0.31
59 INT309369 Ptf1a Positive_regulation of Pax2 1 0.10 0 0.3
60 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
61 INT225021 PDGFB Positive_regulation of Ccl21 1 0.10 0.07 0.3
62 INT225026 PDGFB Positive_regulation of Gene_expression of Ccl21 1 0.10 0.07 0.3
63 INT202313 Gene_expression of PDGFB Positive_regulation of Positive_regulation of Pdgfrb 1 0.14 1 0.29
64 INT215789 Fig4 Positive_regulation of Localization of P2rx7 1 0.03 0.53 0.29
65 INT202314 Gene_expression of PDGFB Positive_regulation of Phosphorylation of Pdgfrb 1 0.14 1 0.29
66 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28
67 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28
68 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27
69 INT355734 Pdgfb Regulation of Bdnf 1 0.22 1.5 0.27
70 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
71 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26
72 INT272157 Gh1 Negative_regulation of Bcl2 1 0.23 1.2 0.26
73 INT272158 Gh1 Regulation of Bcl2 1 0.15 1.2 0.26
74 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26
75 INT205701 P2rx7 Positive_regulation of Il1 1 0.04 0.8 0.25
76 INT260840 NRP2 Positive_regulation of Gene_expression of Bcl2 1 0.00 0.85 0.24
77 INT185489 Atp5o Negative_regulation of P2rx7 1 0.01 0.29 0.24
78 INT316815 Ctgf Negative_regulation of Gene_expression of Sparc 1 0.47 0.64 0.24
79 INT306795 Binding of LEP and SFTPD 1 0.08 1.13 0.23
80 INT216911 Positive_regulation of P2rx7 Positive_regulation of Localization of Plg 1 0.02 0.13 0.23
81 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23
82 INT107219 Binding of P2rx7 and Atp5o 1 0.03 0.07 0.21
83 INT216946 P2rx7 Regulation of Il10 1 0.28 0.17 0.21
84 INT107223 APEH Negative_regulation of P2rx7 1 0.00 0.13 0.21
85 INT226373 IL19 Positive_regulation of Gene_expression of IL5 1 0.02 0.56 0.2
86 INT226336 IL19 Positive_regulation of Gene_expression of IL13 1 0.01 0.56 0.2
87 INT226379 IL19 Positive_regulation of IL5 1 0.02 0.55 0.2
88 INT226377 IL19 Positive_regulation of IL13 1 0.01 0.56 0.2
89 INT226384 INCENP Positive_regulation of IL19 1 0.00 0.58 0.2
90 INT92691 Tgfb1 Positive_regulation of Ctgf 1 0.16 0.91 0.2
91 INT226338 IL19 Positive_regulation of Gene_expression of IL10 1 0.01 0.56 0.2
92 INT226542 Negative_regulation of Adora2b Positive_regulation of IL19 1 0.08 0.58 0.2
93 INT226369 IL19 Positive_regulation of IL4 1 0.03 0.55 0.2
94 INT226525 Adora2b Positive_regulation of IL19 1 0.03 0.58 0.2
95 INT226351 IL19 Positive_regulation of IL10 1 0.01 0.55 0.2
96 INT226353 IL19 Positive_regulation of Gene_expression of IL4 1 0.03 0.56 0.2
97 INT153457 Tgfb1 Positive_regulation of Gene_expression of Ctgf 1 0.13 1.15 0.19
98 INT153460 Inhba Positive_regulation of Gene_expression of Ctgf 1 0.77 1.14 0.19
99 INT153461 Tnf Positive_regulation of Gene_expression of Ctgf 1 0.48 1.13 0.19
100 INT205710 CAMP Positive_regulation of P2rx7 1 0.02 0.47 0.19
101 INT300563 Binding of Drd5 and ADHD1 1 0.01 1.13 0.19
102 INT226349 Binding of IL19 and IL20RA 1 0.00 0.24 0.19
103 INT355733 Pdgfb Regulation of Transcription of Bdnf 1 0.10 0.86 0.19
104 INT236307 SFTPD Positive_regulation of IGKV2D-38 1 0.03 0.57 0.18
105 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17
106 INT226521 IL19 Positive_regulation of Gene_expression of Il6 1 0.01 0.41 0.17
107 INT300305 Mapk14 Positive_regulation of Gene_expression of Ctgf 1 0.19 1.25 0.17
108 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
109 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
110 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
111 INT155233 TXNIP Regulation of BCL2 1 0.23 0.15 0.17
112 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17
113 INT229203 Binding of Bcl2 and Cyp2c11 1 0.36 1.2 0.17
114 INT155068 Csf2 Negative_regulation of Bcl2 1 0.12 1.88 0.17
115 INT226364 IL19 Positive_regulation of Gene_expression of TNF 1 0.11 0.41 0.17
116 INT355732 Pdgfb Negative_regulation of Bdnf 1 0.13 0.87 0.17
117 INT226357 Binding of IL24 and IL19 1 0.01 0.23 0.16
118 INT347445 CD99 Positive_regulation of BCL2 1 0.17 0.95 0.16
119 INT202312 PDGFB Positive_regulation of Gene_expression of Col7a1 1 0.01 0.7 0.16
120 INT202311 PDGFB Positive_regulation of Gene_expression of Fn1 1 0.02 0.7 0.16
121 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15
122 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
123 INT153458 Ctgf Positive_regulation of Gene_expression of Il6 1 0.34 1.03 0.15
124 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
125 INT95104 TGFBR2 Positive_regulation of BCL2 1 0.08 0.61 0.14
126 INT294106 Binding of DNASE1L3 and DRD5 1 0.02 0 0.14
127 INT223084 Binding of Pdgfa and Pdgfb 2 0.17 0.83 0.13
128 INT309139 Edc4 Positive_regulation of Bcl2 1 0.03 0.12 0.13
129 INT148594 Binding of BCL2 and CD34 1 0.39 1.17 0.13
130 INT309142 Edc4 Regulation of Bcl2 1 0.02 0.12 0.13
131 INT246016 Negative_regulation of Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
132 INT270827 P2rx7 Positive_regulation of Localization of Panx1 1 0.41 0.18 0.13
133 INT225024 PDGFB Positive_regulation of Gene_expression of Cxcl5 1 0.16 0.08 0.13
134 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
135 INT348542 BCL2 Negative_regulation of NLRP1 1 0.07 2.02 0.13
136 INT246017 Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
137 INT172899 Binding of Bcl2 and Bcl2l1 3 0.02 5.54 0.12
138 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 0.03 1 0.12
139 INT305194 Bcl2 Positive_regulation of Epo 1 0.06 0.29 0.12
140 INT216945 Positive_regulation of P2rx7 Positive_regulation of Positive_regulation of Casp1 1 0.14 0.18 0.12
141 INT263429 Pdgfb Positive_regulation of Localization of Abl1 1 0.01 0 0.12
142 INT273063 Negative_regulation of Fas Negative_regulation of Positive_regulation of Bcl2 1 0.01 0.72 0.11
143 INT309371 Lhx1 Positive_regulation of Gene_expression of Pax2 1 0.08 0.07 0.11
144 INT74504 Binding of P2rx7 and Rp2 1 0.02 0.19 0.11
145 INT309372 Lhx5 Positive_regulation of Gene_expression of Pax2 1 0.09 0.07 0.11
146 INT221684 Binding of Bcl2 and FRTS 1 0.01 1.19 0.11
147 INT265888 BCL2 Regulation of Gene_expression of BAD 1 0.04 1.08 0.1
148 INT265890 BCL2 Regulation of Gene_expression of BAX 1 0.04 1.08 0.1
149 INT239643 Binding of BCL2 and BCL2L11 3 0.16 2.26 0.09
150 INT282094 Apoa2 Negative_regulation of BCL2 1 0.06 1.15 0.09
151 INT205708 Binding of Icam1 and P2rx7 1 0.08 1.03 0.09
152 INT275183 Bad Positive_regulation of Gene_expression of Bcl2 1 0.08 0.63 0.09
153 INT265887 IGF1 Negative_regulation of BCL2 1 0.09 1.02 0.09
154 INT48194 Pdgfb Positive_regulation of Setd1a 1 0.23 0 0.09
155 INT294637 Bcl2a1a Positive_regulation of Gene_expression of Bcl2 1 0.15 0.97 0.09
156 INT217036 IRF6 Positive_regulation of Gene_expression of P2rx7 1 0.02 0 0.09
157 INT270824 Binding of P2rx7 and Panx1 1 0.34 0.15 0.09
158 INT204300 Bcl2 Negative_regulation of Positive_regulation of Bak1 1 0.02 1.13 0.09
159 INT304464 Binding of P2rx7 and P2rx6 1 0.05 0 0.09
160 INT257342 Mapk4 Positive_regulation of Gene_expression of Ctgf 1 0.01 0.39 0.08
161 INT314011 VEGFA Regulation of IL19 1 0.04 1.11 0.08
162 INT243156 Positive_regulation of P2rx7 Positive_regulation of NOS1 1 0.00 0.08 0.08
163 INT350908 Binding of Bcl2 and Twist1 1 0.04 1.9 0.08
164 INT258756 Binding of Drd5 and Lmo1 1 0.03 0.64 0.08
165 INT270829 P2rx7 Positive_regulation of Panx1 1 0.66 0.08 0.08
166 INT201456 Hmox1 Positive_regulation of Gene_expression of Bcl2 1 0.06 0.74 0.08
167 INT340420 Hmmr Regulation of P2rx7 1 0.01 1.12 0.08
168 INT285025 Bnip3 Positive_regulation of Bak1 1 0.11 0.78 0.07
169 INT204299 Bcl2 Negative_regulation of Localization of Aifm1 1 0.06 1.22 0.07
170 INT285032 Bnip3 Positive_regulation of Bax 1 0.28 0.77 0.07
171 INT223085 Binding of Pdgfb and Insrr 1 0.01 0.91 0.07
172 INT270835 Positive_regulation of P2rx7 Positive_regulation of Localization of DPEP1 1 0.04 0.08 0.07
173 INT297733 Cbr1 Regulation of Gene_expression of Bcl2 1 0.05 0.94 0.07
174 INT279280 Binding of PDGFA and PDGFB 1 0.06 0.9 0.06
175 INT343477 Epo Positive_regulation of Pdgfb 1 0.11 0.31 0.06
176 INT225023 PDGFB Regulation of Transcription of Ccl21 1 0.11 0 0.06
177 INT302177 PTGER2 Positive_regulation of BCL2 1 0.04 2.08 0.06
178 INT94852 PDGFB Regulation of Gene_expression of COL7A1 1 0.09 0.06 0.06
179 INT316819 Sparc Negative_regulation of Gene_expression of Ctgf 1 0.41 0.24 0.06
180 INT225022 PDGFB Regulation of Ccl21 1 0.11 0 0.06
181 INT316822 Sparc Regulation of Gene_expression of Ctgf 1 0.68 0.48 0.06
182 INT352299 Regulation of Binding of BCL2 and VIM 1 0.10 1.07 0.06
183 INT343471 Epo Positive_regulation of Gene_expression of Pdgfb 1 0.11 0.31 0.06
184 INT352298 Binding of BCL2 and VIM 1 0.09 1.06 0.06
185 INT341375 Sod2 Regulation of Bcl2 1 0.08 1.96 0.05
186 INT340427 Positive_regulation of P2rx7 Positive_regulation of Regulation of Pkhd1 1 0.01 1 0.05
187 INT190824 Binding of Cl and Bcl2 1 0.02 1.4 0.05
188 INT333252 Positive_regulation of Binding of Bcl2 and Mcl1 1 0.03 0.88 0.04
189 INT202310 Binding of PDGFB and Pdgfrb 1 0.11 0.39 0.04
190 INT270825 P2rx7 Positive_regulation of Slc37a4 1 0.01 0 0.04
191 INT268664 Ptger2 Positive_regulation of Bcl2 1 0.02 0.9 0.04
192 INT263427 Pdgfb Positive_regulation of Phosphorylation of Rock1 1 0.00 0 0.04
193 INT333245 Binding of Bcl2 and Bcl2l11 1 0.03 0.87 0.04
194 INT268666 Ptger2 Positive_regulation of Gene_expression of Bcl2 1 0.02 0.9 0.04
195 INT223086 Binding of Pdgfb and Pdgfrb 1 0.33 0.46 0.04
196 INT348881 Atpif1 Positive_regulation of If3 1 0.01 0.08 0.04
197 INT348885 Atpif1 Positive_regulation of EIF5B 1 0.01 0.08 0.04
198 INT350905 Binding of Bcl2 and Pcsk4 1 0.03 0.96 0.04
199 INT333253 Binding of Bcl2 and Mcl1 1 0.02 2.14 0.04
200 INT250025 Map3k1 Positive_regulation of Regulation of Bcl2 1 0.01 1.1 0.04

Single Events

The table below shows the top 100 pain related interactions that have been reported for reactive oxygen species metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in reactive oxygen species metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
2 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
3 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
4 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
5 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
6 INT160564 Gene_expression of Il22 64 0.55 59.29 20.9
7 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
8 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
9 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
10 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
11 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
12 INT92686 Gene_expression of Ctgf 51 0.77 34.4 11.93
13 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
14 INT73427 Localization of P2rx7 24 0.79 8.65 9.87
15 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
16 INT48257 Negative_regulation of P2rx7 18 0.41 7.82 8.42
17 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
18 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
19 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
20 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
21 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
22 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
23 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
24 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
25 INT88326 Negative_regulation of P2rx7 16 0.58 8.77 6.25
26 INT94608 Regulation of P2rx7 19 0.23 8.06 6.19
27 INT68882 Binding of P2rx7 16 0.23 4.33 6.17
28 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
29 INT145680 Regulation of P2rx7 22 0.61 11.92 5.42
30 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
31 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
32 INT236335 Gene_expression of SFTPD 26 0.75 15.92 4.59
33 INT92682 Positive_regulation of Gene_expression of Ctgf 17 0.69 12.16 4.51
34 INT74531 Regulation of PDGFB 14 0.26 7.57 4.38
35 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
36 INT185484 Positive_regulation of Gene_expression of P2rx7 8 0.31 7.44 4.28
37 INT296054 Positive_regulation of Il22 13 0.33 17.97 4.06
38 INT144830 Positive_regulation of Gene_expression of P2rx7 22 0.68 9.78 3.92
39 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
40 INT285489 Positive_regulation of Gene_expression of Il22 9 0.32 10.97 3.63
41 INT70897 Positive_regulation of Gene_expression of PDGFB 15 0.57 13.04 3.52
42 INT92681 Positive_regulation of Ctgf 13 0.69 9.78 3.47
43 INT113604 Negative_regulation of Gene_expression of Ctgf 19 0.58 9.37 3.43
44 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
45 INT70895 Localization of PDGFB 20 0.52 8.98 3.4
46 INT129441 Regulation of Gene_expression of P2rx7 8 0.24 4.29 3.32
47 INT162372 Positive_regulation of SFTPD 15 0.67 11.8 3.21
48 INT70885 Gene_expression of Pdgfb 48 0.67 42.27 3.19
49 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
50 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
51 INT144828 Binding of P2rx7 19 0.47 7.84 3.16
52 INT105884 Binding of Bcl2 19 0.35 15.67 3
53 INT107216 Negative_regulation of Gene_expression of P2rx7 10 0.56 3.39 2.61
54 INT306726 Localization of Il22 4 0.57 5.52 2.57
55 INT74527 Positive_regulation of PDGFB 14 0.38 13.31 2.54
56 INT105694 Binding of SFTPD 11 0.46 8.47 2.45
57 INT140091 Gene_expression of Ctgf 26 0.78 14.21 2.39
58 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
59 INT63394 Gene_expression of Drd5 7 0.76 1.85 2.3
60 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
61 INT144829 Localization of P2rx7 12 0.79 2.92 2.12
62 INT63392 Positive_regulation of Drd5 5 0.46 1.73 2.08
63 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
64 INT69702 Positive_regulation of PMAIP1 7 0.35 8.81 1.98
65 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
66 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
67 INT245577 Localization of SFTPD 7 0.63 10.43 1.84
68 INT216936 Negative_regulation of Gene_expression of P2rx7 5 0.42 2.59 1.84
69 INT101958 Positive_regulation of Transcription of Bcl2 4 0.50 2.22 1.65
70 INT137513 Negative_regulation of Positive_regulation of BCL2 6 0.35 5.3 1.62
71 INT212048 Negative_regulation of SFTPD 3 0.42 5.45 1.61
72 INT23786 Positive_regulation of Positive_regulation of P2rx7 5 0.44 2.21 1.58
73 INT125735 Transcription of P2rx7 3 0.62 1.34 1.58
74 INT74528 Negative_regulation of PDGFB 11 0.40 10.34 1.48
75 INT74530 Transcription of PDGFB 7 0.65 4.56 1.47
76 INT215757 Transcription of P2rx7 3 0.21 1.84 1.45
77 INT92685 Transcription of Ctgf 7 0.72 3.92 1.44
78 INT205691 Regulation of Gene_expression of P2rx7 5 0.44 3.25 1.42
79 INT336571 Gene_expression of DRD5 1 0.06 0.73 1.41
80 INT285482 Negative_regulation of Il22 3 0.30 3.02 1.37
81 INT44529 Positive_regulation of Pdgfb 11 0.43 7.98 1.36
82 INT205690 Positive_regulation of Positive_regulation of P2rx7 14 0.68 6.26 1.3
83 INT101107 Positive_regulation of Localization of Bcl2 3 0.48 3.13 1.28
84 INT192349 Negative_regulation of Gene_expression of PDGFB 5 0.31 2.64 1.25
85 INT285470 Regulation of Il22 4 0.11 4.18 1.21
86 INT70886 Positive_regulation of Gene_expression of Pdgfb 13 0.45 12.57 1.17
87 INT158565 Regulation of Ctgf 3 0.61 3.93 1.14
88 INT103859 Positive_regulation of Drd5 2 0.49 0.81 1.14
89 INT180975 Gene_expression of IL19 20 0.75 9.12 1.13
90 INT158563 Negative_regulation of Ctgf 6 0.56 4.31 1.12
91 INT172855 Binding of Bcl2 37 0.32 23.41 1.09
92 INT70021 Localization of BCL2 23 0.74 21.6 1.09
93 INT103857 Gene_expression of Drd5 2 0.23 0.92 1.08
94 INT63393 Positive_regulation of Gene_expression of Drd5 3 0.49 1.21 1.02
95 INT105986 Positive_regulation of Transcription of Ctgf 2 0.69 2.43 1.01
96 INT216661 Regulation of Positive_regulation of P2rx7 1 0.07 0 1
97 INT306723 Binding of Il22 3 0.11 2.44 0.97
98 INT346123 Negative_regulation of Gene_expression of Il22 3 0.30 1.97 0.97
99 INT113887 Positive_regulation of Negative_regulation of P2rx7 1 0.22 1.02 0.96
100 INT85999 Binding of Drd5 2 0.27 0.84 0.94
101 INT151115 Regulation of Regulation of Bcl2 4 0.21 4.12 0.88
102 INT92117 Phosphorylation of BCL2 26 0.80 9.93 0.86
103 INT151776 Positive_regulation of Transcription of P2rx7 1 0.03 0.53 0.86
104 INT236328 Regulation of SFTPD 6 0.38 3.04 0.85
105 INT70019 Binding of BCL2 25 0.47 17.55 0.79
106 INT271589 Regulation of Transcription of P2rx7 1 0.05 0.5 0.78
107 INT109404 Transcription of BCL2 6 0.69 4.49 0.77
108 INT124844 Regulation of Positive_regulation of Bcl2 3 0.43 2.55 0.75
109 INT155392 Negative_regulation of Negative_regulation of Bcl2 3 0.21 1.64 0.74
110 INT226464 Localization of IL19 3 0.73 1.69 0.72
111 INT134444 Positive_regulation of Binding of Bcl2 3 0.47 2.67 0.72
112 INT25663 Localization of PMAIP1 3 0.38 2.47 0.71
113 INT202307 Regulation of Gene_expression of PDGFB 2 0.26 1.24 0.71
114 INT300588 Regulation of Drd5 1 0.32 0.67 0.69
115 INT306800 Positive_regulation of Localization of SFTPD 1 0.16 2.1 0.68
116 INT184846 Negative_regulation of Drd5 1 0.19 2.28 0.68
117 INT125734 Negative_regulation of Transcription of P2rx7 1 0.38 0.81 0.67
118 INT25664 Negative_regulation of Localization of PMAIP1 1 0.09 0.09 0.66
119 INT236330 Regulation of Gene_expression of SFTPD 2 0.59 1.55 0.65
120 INT74529 Binding of PDGFB 13 0.36 7.41 0.62
121 INT306730 Regulation of Gene_expression of Il22 1 0.06 1.04 0.62
122 INT185485 Negative_regulation of Localization of P2rx7 1 0.26 0.95 0.62
123 INT164585 Regulation of PMAIP1 2 0.20 2.07 0.61
124 INT277699 Gene_expression of Pdgfb 5 0.20 4.84 0.59
125 INT70025 Positive_regulation of Positive_regulation of BCL2 3 0.27 0.96 0.58
126 INT103858 Regulation of Gene_expression of Drd5 1 0.08 0.92 0.58
127 INT178128 Negative_regulation of Phosphorylation of BCL2 7 0.27 3.94 0.56
128 INT202306 Negative_regulation of Localization of PDGFB 2 0.25 0.76 0.55
129 INT155090 Regulation of Positive_regulation of BCL2 3 0.26 1.78 0.54
130 INT192946 Gene_expression of PMAIP1 2 0.27 1.77 0.52
131 INT157718 Binding of DRD5 1 0.33 0.57 0.52
132 INT164584 Positive_regulation of Positive_regulation of PMAIP1 1 0.20 0.9 0.52
133 INT144696 Regulation of Transcription of Bcl2 5 0.44 2.96 0.51
134 INT153099 Negative_regulation of Positive_regulation of P2rx7 1 0.42 0.25 0.5
135 INT180974 Positive_regulation of Gene_expression of IL19 4 0.49 2.66 0.49
136 INT134445 Positive_regulation of Positive_regulation of Bcl2 3 0.47 2.43 0.49
137 INT215732 Negative_regulation of Binding of P2rx7 1 0.11 0.74 0.49
138 INT202309 Regulation of Localization of PDGFB 1 0.36 0.92 0.49
139 INT221676 Protein_catabolism of Bcl2 4 0.24 2.77 0.48
140 INT167377 Regulation of Gene_expression of Ctgf 2 0.25 1.35 0.48
141 INT27543 Positive_regulation of ALOX12 1 0.09 2.09 0.48
142 INT158296 Positive_regulation of Gene_expression of Ctgf 5 0.47 4.82 0.47
143 INT223081 Negative_regulation of Gene_expression of Pdgfb 2 0.37 3.07 0.47
144 INT313617 Positive_regulation of Pdgfb 4 0.35 1.53 0.46
145 INT204052 Transcription of Bcl2 5 0.51 3.25 0.45
146 INT278114 Negative_regulation of Negative_regulation of P2rx7 1 0.21 0 0.45
147 INT140090 Negative_regulation of Gene_expression of Ctgf 5 0.58 1.77 0.44
148 INT140295 Protein_catabolism of BCL2 4 0.64 5.7 0.44
149 INT220424 Positive_regulation of Negative_regulation of Bcl2 2 0.14 1.81 0.44
150 INT314034 Negative_regulation of Localization of IL19 1 0.41 0.86 0.44
151 INT353938 Positive_regulation of Negative_regulation of Il22 1 0.36 0.9 0.44
152 INT215741 Positive_regulation of Transcription of P2rx7 1 0.15 1.15 0.43
153 INT70884 Localization of Pdgfb 8 0.35 6.22 0.42
154 INT220436 Binding of IL19 4 0.36 1.92 0.41
155 INT199078 Gene_expression of Nox4 3 0.59 3.83 0.41
156 INT76143 Positive_regulation of Regulation of PDGFB 1 0.01 0.08 0.4
157 INT74532 Positive_regulation of Transcription of PDGFB 1 0.57 0.73 0.4
158 INT155724 Negative_regulation of Transcription of Bcl2 6 0.53 2.35 0.37
159 INT285496 Regulation of Negative_regulation of Il22 1 0.10 1.13 0.37
160 INT344086 Binding of Drd5 1 0.36 0.06 0.37
161 INT317875 Binding of Pdgfb 3 0.10 1.15 0.36
162 INT153261 Positive_regulation of Localization of PDGFB 2 0.37 1.98 0.36
163 INT119248 Binding of Ctgf 1 0.35 1.5 0.35
164 INT213507 Gene_expression of Pax2 10 0.67 1.41 0.34
165 INT225264 Positive_regulation of IL19 4 0.49 1.58 0.34
166 INT316678 Regulation of Positive_regulation of SFTPD 1 0.38 0.96 0.34
167 INT153465 Regulation of Gene_expression of Ctgf 3 0.61 2.5 0.33
168 INT121239 Regulation of Positive_regulation of P2rx7 2 0.61 1.32 0.32
169 INT236323 Positive_regulation of Transcription of SFTPD 1 0.12 0.47 0.32
170 INT236324 Transcription of SFTPD 1 0.17 0.47 0.32
171 INT236327 Positive_regulation of Gene_expression of SFTPD 1 0.12 0.47 0.32
172 INT253424 Protein_catabolism of SFTPD 2 0.74 1.12 0.31
173 INT306727 Positive_regulation of Positive_regulation of Il22 1 0.12 1.26 0.3
174 INT285014 Gene_expression of Bnip3 4 0.61 10.38 0.29
175 INT168140 Regulation of Ctgf 2 0.60 2.15 0.29
176 INT309354 Regulation of Pax2 1 0.10 0 0.29
177 INT216937 Regulation of Binding of P2rx7 1 0.44 0.08 0.29
178 INT178114 Positive_regulation of Phosphorylation of BCL2 11 0.49 4.44 0.28
179 INT309339 Negative_regulation of Localization of Pax2 1 0.15 0 0.28
180 INT300593 Regulation of Gene_expression of Drd5 1 0.33 0.13 0.28
181 INT224441 Negative_regulation of Pdgfb 2 0.33 1.61 0.27
182 INT136840 Positive_regulation of Ctgf 2 0.35 1.34 0.27
183 INT292743 Negative_regulation of Binding of Bcl2 1 0.05 1.97 0.24
184 INT216938 Negative_regulation of Localization of P2rx7 1 0.37 0.25 0.24
185 INT285003 Positive_regulation of Regulation of Bcl2 1 0.46 0.68 0.23
186 INT349702 Positive_regulation of Transcription of Pdgfb 1 0.35 0 0.23
187 INT277701 Localization of Pdgfb 3 0.23 1.49 0.22
188 INT349701 Transcription of Pdgfb 1 0.40 0 0.22
189 INT108563 Negative_regulation of Regulation of Bcl2 1 0.32 0.74 0.22
190 INT133762 Gene_expression of Atpif1 3 0.17 0.34 0.21
191 INT226485 Regulation of IL19 1 0.07 0.56 0.21
192 INT216940 Negative_regulation of Binding of P2rx7 1 0.37 0.15 0.2
193 INT158567 Negative_regulation of Transcription of Ctgf 1 0.43 0.73 0.2
194 INT220426 Regulation of Negative_regulation of Bcl2 1 0.05 0.81 0.18
195 INT216889 Phosphorylation of P2rx7 1 0.23 0 0.18
196 INT220437 Negative_regulation of IL19 1 0.41 0.68 0.18
197 INT238507 Regulation of Regulation of BCL2 3 0.44 5.14 0.16
198 INT101109 Negative_regulation of Localization of Bcl2 1 0.03 0.62 0.16
199 INT307467 Regulation of Binding of P2rx7 1 0.08 0 0.16
200 INT229235 Regulation of Localization of BCL2 2 0.29 3.7 0.15
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