GO:0072661

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Name protein targeting to plasma membrane
Categary Process
Go Slim No
Go Link GO:0072661
Unique Molecular Interactions 58
Total Molecular Interactions 79
Total Single Events 199
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein targeting to plasma membrane. They are ordered first by their pain relevance and then by number of times they were reported for protein targeting to plasma membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT309708 Palm Regulation of Positive_regulation of Penk 1 0.19 1.25 0.91
2 INT139079 Tnip1 Negative_regulation of Ptch1 1 0.20 0.63 0.62
3 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
4 INT28562 SOD1 Negative_regulation of Pacs1 1 0.03 2.63 0.19
5 INT299113 Binding of INPP5K and GOPC 1 0.18 2.69 0.19
6 INT67619 Inpp5k Negative_regulation of Ptgs1 1 0.03 0.5 0.13
7 INT345343 PTCH1 Regulation of Negative_regulation of SMO 1 0.09 2.3 0.13
8 INT312218 INPP5K Positive_regulation of Protein_catabolism of IGFBP3 1 0.17 0.39 0.11
9 INT312212 Binding of ADAM12 and INPP5K 1 0.16 0.46 0.11
10 INT262751 Binding of PTCH1 and SMO 1 0.25 1.29 0.1
11 INT270457 Binding of Ptch1 and Gli1 1 0.02 1.3 0.08
12 INT312228 INPP5K Regulation of TGFB1 1 0.06 0.08 0.05
13 INT312226 INPP5K Positive_regulation of IGFBP5 1 0.12 0.07 0.05
14 INT255756 Ptch1 Positive_regulation of Phosphorylation of Pik3r1 1 0.16 1.08 0.03
15 INT255733 Ptch1 Positive_regulation of Pik3r1 1 0.16 1.08 0.03
16 INT312224 INPP5K Regulation of Negative_regulation of COL1A1 1 0.08 0 0
17 INT255758 Ptch1 Positive_regulation of Akt1 1 0.21 1.14 0
18 INT312221 Binding of TGFB1 and INPP5K 1 0.09 0 0
19 INT255732 Ptch1 Positive_regulation of hs 1 0.06 1.26 0
20 INT312220 IL4 Positive_regulation of Regulation of INPP5K 1 0.05 0.24 0
21 INT312222 IFNA1 Positive_regulation of Regulation of INPP5K 1 0.05 0.24 0
22 INT205975 Binding of PTCH1 and Smo 1 0.02 0.72 0
23 INT255755 Ptch1 Regulation of Positive_regulation of Ins1 1 0.05 0.28 0
24 INT312230 INPP5K Regulation of Gene_expression of COL2A1 1 0.06 0 0
25 INT312225 Positive_regulation of INPP5K Positive_regulation of CD44 1 0.15 0.1 0
26 INT205958 GLI1 Positive_regulation of Gene_expression of PTCH1 1 0.35 0.57 0
27 INT205960 Binding of PTCH1 and SHH 1 0.21 0.71 0
28 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
29 INT312214 INPP5K Regulation of Gene_expression of COL1A1 1 0.08 0 0
30 INT255753 Ptch1 Positive_regulation of Phosphorylation of Gopc 1 0.13 1.33 0
31 INT312223 INPP5K Negative_regulation of Gene_expression of COL10A1 1 0.04 0.1 0
32 INT312227 INPP5K Regulation of Negative_regulation of COL2A1 1 0.06 0 0
33 INT260074 Binding of BRCA2 and PTCH1 1 0.40 0.15 0
34 INT256632 Binding of PTCH1 and Jkamp 1 0.00 2.32 0
35 INT312215 INPP5K Negative_regulation of COL10A1 1 0.03 0.1 0
36 INT255744 Binding of hs and Ptch1 1 0.06 1.32 0
37 INT205965 Binding of Ptch1 and Smo 1 0.03 0.72 0
38 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
39 INT255750 Ptch1 Positive_regulation of Ins1 1 0.10 0.35 0
40 INT260073 Binding of FANCC and PTCH1 1 0.33 0.49 0
41 INT312229 INPP5K Positive_regulation of CD44 1 0.15 0.1 0
42 INT312216 INPP5K Negative_regulation of Gene_expression of RUNX2 1 0.15 0.1 0
43 INT260067 Binding of PTCH1 and XPA 1 0.26 1.08 0
44 INT205976 Binding of Ptch1 and SMOX 1 0.21 0.72 0
45 INT205962 Binding of PTCH1 and SMOX 1 0.14 0.72 0
46 INT255734 Ptch1 Regulation of Ins1 1 0.09 1.46 0
47 INT255760 Ptch1 Regulation of TNF 1 0.13 1.33 0
48 INT255741 Ptch1 Positive_regulation of Phosphorylation of Ins1 1 0.09 2.21 0
49 INT205977 Binding of SHH and Ptch1 1 0.31 0.71 0
50 INT205961 GLI1 Positive_regulation of Negative_regulation of PTCH1 1 0.25 0.58 0
51 INT312213 INPP5K Regulation of COL2A1 1 0.06 0 0
52 INT243232 Ighmbp2 Negative_regulation of Ptch1 1 0.02 0.22 0
53 INT312217 Binding of INS and INPP5K 1 0.03 0 0
54 INT255749 Ptch1 Positive_regulation of Phosphorylation of Slc2a4 1 0.15 1.32 0
55 INT255735 Ptch1 Positive_regulation of Phosphorylation of Akt1 1 0.27 2.83 0
56 INT255746 Hspa1a Positive_regulation of Positive_regulation of Ptch1 1 0.19 0.99 0
57 INT255739 Ptch1 Positive_regulation of Gene_expression of Hspa1a 1 0.18 0.75 0
58 INT255759 Ptch1 Positive_regulation of Phosphorylation of hs 1 0.06 1.34 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein targeting to plasma membrane. They are ordered first by their pain relevance and then by number of times they were reported in protein targeting to plasma membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15157 Gene_expression of INPP5K 30 0.67 15.49 2.85
2 INT67618 Positive_regulation of Inpp5k 3 0.45 0.77 2.64
3 INT141455 Negative_regulation of Inpp5k 2 0.36 1.09 1.51
4 INT113151 Positive_regulation of Ptch1 7 0.64 3.8 1.41
5 INT125296 Regulation of Inpp5k 1 0.22 0 1.32
6 INT139077 Negative_regulation of Ptch1 5 0.56 5.22 1.29
7 INT143846 Positive_regulation of INPP5K 5 0.40 6.4 1.17
8 INT135299 Binding of PTCH1 10 0.48 12.16 0.84
9 INT142416 Binding of Ptch1 6 0.34 4.92 0.74
10 INT153257 Regulation of Ptch1 6 0.36 5.92 0.67
11 INT131421 Localization of INPP5K 9 0.74 4.3 0.59
12 INT299115 Regulation of INPP5K 6 0.39 4.11 0.59
13 INT65919 Gene_expression of Ptch1 11 0.75 6.47 0.56
14 INT327693 Regulation of Palm 1 0.18 0 0.54
15 INT309707 Positive_regulation of Palm 1 0.39 0.28 0.46
16 INT132881 Binding of INPP5K 7 0.48 4.35 0.33
17 INT119907 Binding of Inpp5k 3 0.33 0.6 0.32
18 INT183055 Gene_expression of PTCH1 10 0.77 15.54 0.26
19 INT173164 Negative_regulation of INPP5K 4 0.51 2.01 0.24
20 INT146414 Binding of Pacs1 2 0.30 0.06 0.2
21 INT146413 Positive_regulation of Binding of Pacs1 1 0.40 0.06 0.2
22 INT260083 Regulation of PTCH1 11 0.27 4.46 0.09
23 INT270454 Regulation of Transcription of Ptch1 1 0.25 0.55 0.09
24 INT28560 Positive_regulation of Pacs1 1 0.07 1.33 0.09
25 INT270450 Transcription of Ptch1 1 0.49 0.55 0.09
26 INT165148 Regulation of Binding of Ptch1 1 0.22 0.08 0.08
27 INT270452 Regulation of Gene_expression of Ptch1 1 0.25 0.25 0.08
28 INT165154 Negative_regulation of Positive_regulation of Ptch1 1 0.34 0.09 0.07
29 INT183056 Positive_regulation of Transcription of PTCH1 1 0.28 0.46 0.07
30 INT299116 Regulation of Gene_expression of INPP5K 1 0.39 1.13 0.06
31 INT255719 Phosphorylation of Ptch1 1 0.32 3.7 0.06
32 INT322923 Positive_regulation of Positive_regulation of INPP5K 1 0.39 1.51 0.06
33 INT255726 Localization of Ptch1 1 0.33 1.74 0.05
34 INT183070 Transcription of PTCH1 2 0.68 0.95 0.04
35 INT285357 Positive_regulation of Gene_expression of Inpp5k 1 0.16 0.17 0.03
36 INT285359 Gene_expression of Inpp5k 1 0.22 0.17 0.03
37 INT183064 Regulation of Gene_expression of PTCH1 1 0.34 0.22 0.03
38 INT205968 Negative_regulation of PTCH1 2 0.58 2.35 0
39 INT255723 Positive_regulation of Gene_expression of Ptch1 2 0.39 1.3 0
40 INT256631 Positive_regulation of PTCH1 2 0.13 1.97 0
41 INT260088 Negative_regulation of Transcription of PTCH1 1 0.43 0.4 0
42 INT260089 Localization of PTCH1 1 0.70 0.37 0
43 INT270455 Negative_regulation of Gene_expression of Ptch1 1 0.39 0.66 0
44 INT315772 Gene_expression of Pacs1 1 0.03 1.44 0
45 INT183052 Positive_regulation of Gene_expression of PTCH1 1 0.38 0.26 0
46 INT260080 Negative_regulation of Gene_expression of PTCH1 1 0.58 2.09 0
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