GO:0072686

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Name mitotic spindle
Categary Component
Go Slim No
Go Link GO:0072686
Unique Molecular Interactions 54
Total Molecular Interactions 57
Total Single Events 279
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for mitotic spindle. They are ordered first by their pain relevance and then by number of times they were reported for mitotic spindle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT93781 Racgap1 Positive_regulation of Positive_regulation of Gnptab 1 0.02 0.07 1.49
2 INT93782 Racgap1 Positive_regulation of Rgs9 1 0.55 0.07 1.49
3 INT93783 Racgap1 Positive_regulation of Gnptab 1 0.02 0.07 1.49
4 INT70288 Negative_regulation of Atxn2l Positive_regulation of Racgap1 1 0.02 0.3 1.19
5 INT70289 Atxn2l Positive_regulation of Racgap1 1 0.04 0.29 1.15
6 INT221747 Gtf3a Positive_regulation of Positive_regulation of Racgap1 1 0.00 0.33 1
7 INT65462 Bri3 Negative_regulation of Racgap1 1 0.02 0.39 0.93
8 INT97949 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of CDC42 1 0.06 0.72 0.51
9 INT97953 ST3GAL3 Positive_regulation of CDC42 1 0.09 0.7 0.5
10 INT330107 Racgap1 Regulation of Positive_regulation of Nox3 1 0.01 0.87 0.49
11 INT330108 Racgap1 Positive_regulation of Cybb 1 0.03 0.86 0.46
12 INT330110 Racgap1 Regulation of Gene_expression of Ros1 1 0.00 1.12 0.41
13 INT71925 Binding of Ptprs and Positive_regulation of Racgap1 1 0.10 0 0.35
14 INT71924 Ptprs Positive_regulation of Racgap1 1 0.10 0 0.35
15 INT330106 Racgap1 Positive_regulation of Positive_regulation of Mapk8 1 0.01 1.32 0.35
16 INT330109 Binding of Racgap1 and Rac1 1 0.03 1.22 0.32
17 INT285567 Binding of IL1B and Cdc42 1 0.03 0.77 0.31
18 INT126942 Binding of PKD2 and ZACN 1 0.00 1.38 0.28
19 INT269490 Binding of Racgap1 and HHIP 1 0.00 0 0.27
20 INT292565 MAP3K5 Positive_regulation of Positive_regulation of CDC42 1 0.02 0 0.23
21 INT71923 Ptprs Regulation of Racgap1 1 0.09 0 0.21
22 INT126944 Binding of PKD2 and Pkd1 2 0.08 2.09 0.19
23 INT231836 Pcdh8 Regulation of Positive_regulation of Racgap1 1 0.00 0.58 0.18
24 INT231866 INCENP Regulation of Positive_regulation of Racgap1 1 0.00 0.58 0.18
25 INT354823 IFNA1 Positive_regulation of Racgap1 1 0.00 1.4 0.15
26 INT337164 Binding of DIAPH1 and Iqgap1 1 0.53 0.37 0.14
27 INT269491 Racgap1 Negative_regulation of RAB5A 1 0.01 0 0.12
28 INT287267 EGF Positive_regulation of CDC42 1 0.12 0.16 0.11
29 INT202407 Binding of Osm and Racgap1 1 0.04 0.13 0.09
30 INT202399 Binding of Mapk14 and Racgap1 1 0.07 0.13 0.09
31 INT221470 Binding of Racgap1 and Camkk2 1 0.00 0.06 0.05
32 INT221469 Binding of Racgap1 and Rrad 1 0.02 0.06 0.05
33 INT340427 Positive_regulation of P2rx7 Positive_regulation of Regulation of Pkhd1 1 0.01 1 0.05
34 INT215240 Binding of Myo1f and Racgap1 1 0.01 0.77 0.04
35 INT215244 Binding of Racgap1 and Mlph 1 0.04 0.76 0.04
36 INT181083 Binding of Akt1 and Cdc42 1 0.00 0.79 0.03
37 INT241459 Gart Positive_regulation of Racgap1 1 0.01 0 0.03
38 INT183896 Gene_expression of CAV1 Negative_regulation of Positive_regulation of Racgap1 1 0.01 0.64 0.03
39 INT295702 PTGER2 Positive_regulation of Racgap1 1 0.05 0.22 0
40 INT295701 Positive_regulation of Binding of RAC1 and Racgap1 1 0.28 0.16 0
41 INT295704 Positive_regulation of Binding of RHOA and Racgap1 1 0.15 0.16 0
42 INT326163 Binding of Racgap1 and RAB12 1 0.00 0.68 0
43 INT183895 CAV1 Regulation of Positive_regulation of Racgap1 1 0.01 0.37 0
44 INT234996 Ctnnd1 Positive_regulation of CDC42 1 0.01 0.07 0
45 INT261883 PKD2 Positive_regulation of Localization of Ca2 1 0.02 0.67 0
46 INT194333 Binding of MFN2 and Racgap1 1 0.01 0.38 0
47 INT249148 Binding of Was and Racgap1 1 0.03 0.18 0
48 INT295700 Binding of RAC1 and Racgap1 1 0.21 0.16 0
49 INT183897 Binding of RHOC and Racgap1 1 0.01 0.2 0
50 INT249149 Binding of Cdc42 and Was 1 0.08 0.18 0
51 INT286589 Binding of PKHD1 and Pkd2 1 0.09 0.52 0
52 INT295703 Binding of RHOA and Racgap1 1 0.11 0.16 0
53 INT271978 Positive_regulation of Racgap1 Regulation of Mtor 1 0.00 0.54 0
54 INT181085 Binding of Cdc42 and Errfi1 1 0.08 0.67 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for mitotic spindle. They are ordered first by their pain relevance and then by number of times they were reported in mitotic spindle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT12725 Positive_regulation of Racgap1 66 0.68 32.74 19.29
2 INT60285 Negative_regulation of Racgap1 27 0.56 21.71 8.14
3 INT52839 Regulation of Racgap1 14 0.25 9.46 3.37
4 INT70286 Negative_regulation of Positive_regulation of Racgap1 2 0.43 3.78 2.42
5 INT54515 Positive_regulation of Positive_regulation of Racgap1 6 0.12 2.33 2.34
6 INT70283 Gene_expression of Racgap1 19 0.44 9.64 2.33
7 INT65459 Binding of Racgap1 9 0.07 4.57 2.28
8 INT97955 Positive_regulation of CDC42 8 0.49 2.47 1.19
9 INT161682 Positive_regulation of Cdc42 8 0.53 4.55 0.9
10 INT330076 Regulation of Positive_regulation of Racgap1 1 0.04 1.98 0.73
11 INT137850 Gene_expression of PKD2 9 0.65 6.68 0.63
12 INT289327 Regulation of Negative_regulation of Racgap1 2 0.05 2.09 0.62
13 INT180107 Regulation of Cdc42 3 0.16 0.18 0.6
14 INT97956 Negative_regulation of CDC42 3 0.27 1.58 0.55
15 INT199077 Localization of Racgap1 7 0.73 2.43 0.42
16 INT288080 Regulation of Gene_expression of Racgap1 3 0.04 3.42 0.41
17 INT330074 Negative_regulation of Binding of Racgap1 1 0.03 1.47 0.35
18 INT330075 Negative_regulation of Transcription of Racgap1 1 0.03 1.05 0.33
19 INT330077 Transcription of Racgap1 1 0.05 1.04 0.33
20 INT270418 Negative_regulation of Negative_regulation of Racgap1 1 0.02 0.53 0.31
21 INT183881 Localization of CDC42 3 0.49 1.92 0.23
22 INT183876 Regulation of CDC42 3 0.30 1.94 0.19
23 INT197290 Gene_expression of Cdc42 9 0.35 2.52 0.15
24 INT251975 Positive_regulation of Pkhd1 5 0.10 8.98 0.15
25 INT337163 Localization of DIAPH1 1 0.68 0.41 0.14
26 INT206133 Binding of CDC42 3 0.25 0.8 0.12
27 INT197282 Positive_regulation of Gene_expression of Cdc42 3 0.26 0.12 0.08
28 INT286583 Localization of PKD2 1 0.35 0.17 0.06
29 INT261879 Binding of PKD2 3 0.13 2.59 0.05
30 INT206169 Gene_expression of CDC42 2 0.26 1.05 0.05
31 INT206167 Positive_regulation of Gene_expression of CDC42 1 0.08 0.05 0.05
32 INT340406 Regulation of Pkhd1 1 0.01 0.99 0.05
33 INT288079 Positive_regulation of Gene_expression of Racgap1 1 0.06 0.74 0.04
34 INT206049 Negative_regulation of Localization of Racgap1 1 0.01 0.12 0.04
35 INT286581 Gene_expression of PKHD1 1 0.24 0.19 0.03
36 INT340405 Gene_expression of Pkhd1 1 0.03 1.14 0.03
37 INT286580 Positive_regulation of Gene_expression of PKHD1 1 0.16 0.1 0.03
38 INT292996 Binding of Pkhd1 3 0.07 3.12 0
39 INT241245 Negative_regulation of PKD2 2 0.42 2.35 0
40 INT254795 Negative_regulation of Cdc42 2 0.12 1.53 0
41 INT270614 Localization of Cdc42 1 0.55 0.95 0
42 INT197294 Regulation of Gene_expression of Cdc42 1 0.13 0 0
43 INT246980 Binding of DIAPH1 1 0.04 0.11 0
44 INT286588 Positive_regulation of Localization of PKHD1 1 0.16 0.79 0
45 INT286576 Binding of PKHD1 1 0.12 0.63 0
46 INT282269 Binding of Cdc42 1 0.08 0.33 0
47 INT232493 Negative_regulation of Positive_regulation of PKD2 1 0.23 0.61 0
48 INT297037 Regulation of DIAPH1 1 0.27 0.1 0
49 INT261878 Negative_regulation of Binding of PKD2 1 0.14 0.6 0
50 INT287281 Positive_regulation of Positive_regulation of CDC42 1 0.26 0 0
51 INT282272 Positive_regulation of Binding of Cdc42 1 0.11 0.33 0
52 INT232491 Positive_regulation of PKD2 1 0.27 0.56 0
53 INT269630 Positive_regulation of DIAPH1 1 0.01 0 0
54 INT286584 Positive_regulation of PKHD1 1 0.13 1.01 0
55 INT286579 Localization of PKHD1 1 0.24 0.79 0
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