GO:0090004

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Name positive regulation of establishment of protein localization in plasma membrane
Categary Process
Go Slim No
Go Link GO:0090004
Unique Molecular Interactions 672
Total Molecular Interactions 912
Total Single Events 5842
Pain Genes Associated 16

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of establishment of protein localization in plasma membrane. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of establishment of protein localization in plasma membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
2 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79
3 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
4 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
5 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
6 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
7 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
8 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
9 INT151965 SORBS1 Positive_regulation of TRPV1 1 0.18 0 1.89
10 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
11 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
12 INT122428 Binding of Ighm and Prkci 1 0.00 0 1.66
13 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
14 INT180812 Gdnf Positive_regulation of Gene_expression of Sorbs1 1 0.02 0.83 1.61
15 INT180811 Gdnf Positive_regulation of Regulation of Sorbs1 1 0.01 0.83 1.61
16 INT180804 Bdnf Positive_regulation of Gene_expression of Sorbs1 1 0.01 0 1.44
17 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
18 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
19 INT180809 Ngf Positive_regulation of Positive_regulation of Sorbs1 1 0.03 0.84 1.4
20 INT180808 Ngf Positive_regulation of Gene_expression of Sorbs1 1 0.03 0.84 1.4
21 INT122430 Negative_regulation of Binding of Ighm and Prkci 1 0.00 0 1.36
22 INT180802 Gdnf Positive_regulation of Sorbs1 1 0.02 0.98 1.34
23 INT180807 Calca Regulation of Sorbs1 1 0.02 0 1.32
24 INT153589 Binding of PRKCI and Oprm1 1 0.06 0 1.17
25 INT68157 Alox5 Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.13
26 INT68154 Mthfs Positive_regulation of Pdpk1 1 0.01 0.63 1.12
27 INT68158 Pla2g1b Positive_regulation of Pdpk1 1 0.05 0.63 1.12
28 INT68159 Pla2g1b Positive_regulation of Positive_regulation of Pdpk1 1 0.05 0.64 1.12
29 INT68163 Mthfs Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.12
30 INT68165 Alox5 Positive_regulation of Pdpk1 1 0.01 0.63 1.12
31 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
32 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
33 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
34 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
35 INT108547 AKT1 Regulation of MAPKAPK5 1 0.04 1.2 1.08
36 INT122432 Prkci Regulation of Negative_regulation of Oprd1 1 0.01 0 1.06
37 INT180806 Ngf Positive_regulation of Regulation of Sorbs1 1 0.03 0.28 1.04
38 INT151218 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.26 1.03
39 INT122429 Prkci Regulation of Gene_expression of Ighm 1 0.00 0 1.02
40 INT122431 Prkci Negative_regulation of Negative_regulation of Ighm 1 0.00 0 1.02
41 INT122433 Prkci Negative_regulation of Ighm 1 0.00 0 1.02
42 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
43 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96
44 INT180803 Sorbs1 Regulation of Gdnf 1 0.01 0.28 0.95
45 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
46 INT107335 Pdpk1 Positive_regulation of Regulation of Sigmar1 1 0.02 0 0.93
47 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
48 INT317541 Oprd1 Negative_regulation of Akt1 1 0.06 0 0.91
49 INT249012 Binding of Akt1 and Gabrg1 1 0.01 0 0.9
50 INT132226 Binding of Akt1 and Pik3cg 1 0.30 0.49 0.9
51 INT54854 Sorbs1 Regulation of Ins1 1 0.34 0.23 0.9
52 INT199109 Binding of Akt1 and Arhgdia 1 0.02 2.73 0.87
53 INT69084 Binding of Adrb1 and Positive_regulation of Positive_regulation of Pdpk1 1 0.02 0.08 0.83
54 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
55 INT317556 Phosphorylation of Gopc Positive_regulation of Akt1 1 0.10 0.08 0.82
56 INT317514 Akt1 Regulation of Localization of Oprm1 1 0.21 0.07 0.82
57 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
58 INT111888 Akt1 Regulation of Regulation of Oprm1 1 0.04 0 0.77
59 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
60 INT335592 Ltp Positive_regulation of Positive_regulation of Akt1 1 0.01 0.19 0.74
61 INT162164 ARF6 Regulation of Positive_regulation of PLD2 1 0.60 0 0.74
62 INT106527 Akt1 Positive_regulation of Jun 1 0.05 0.53 0.74
63 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
64 INT162162 ARF6 Regulation of OPRM1 1 0.19 0 0.71
65 INT180805 Bdnf Regulation of Sorbs1 1 0.01 0.14 0.67
66 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
67 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66
68 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65
69 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
70 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
71 INT317560 Binding of Pdpk1 and Pik3r1 1 0.13 0 0.65
72 INT169293 PTPLA Positive_regulation of AKT1 1 0.10 0.15 0.64
73 INT134047 Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
74 INT134044 Positive_regulation of Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
75 INT278695 MTX1 Negative_regulation of Phosphorylation of AKT1 1 0.04 0.81 0.62
76 INT200808 Binding of Akt1 and Insrr 2 0.00 0.98 0.61
77 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61
78 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6
79 INT248994 Binding of Akt1 and Ptar1 1 0.00 0 0.58
80 INT323176 PRKCA Positive_regulation of Phosphorylation of Akt1 1 0.02 0 0.56
81 INT302832 Tnfsf10 Positive_regulation of Akt1 1 0.04 1.63 0.56
82 INT201944 CXCL10 Positive_regulation of Phosphorylation of AKT1 1 0.09 0.79 0.55
83 INT114064 Agtr2 Positive_regulation of Phosphorylation of Akt1 1 0.24 0.41 0.54
84 INT282284 Cpox Positive_regulation of Akt1 1 0.02 0.47 0.54
85 INT282282 Ptger2 Positive_regulation of Akt1 1 0.03 0.47 0.54
86 INT162994 Binding of Akt1 and Trib3 1 0.04 0.09 0.54
87 INT127320 Gpx3 Regulation of Akt1 2 0.00 3.11 0.53
88 INT317523 Oprm1 Positive_regulation of Gene_expression of Akt1 1 0.32 0.05 0.53
89 INT5631 Ubqln1 Positive_regulation of Pdpk1 1 0.05 0 0.53
90 INT109307 Pik3r1 Positive_regulation of Phosphorylation of Akt1 1 0.29 0.4 0.53
91 INT317574 Oprm1 Positive_regulation of Akt1 1 0.22 0.05 0.52
92 INT97952 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of AKT1 1 0.03 0.72 0.51
93 INT151221 Negative_regulation of SIGMAR1 Negative_regulation of Akt1 1 0.00 0.13 0.51
94 INT97951 ST3GAL3 Positive_regulation of AKT1 1 0.04 0.7 0.5
95 INT102844 Pdc Regulation of Akt1 1 0.03 0 0.49
96 INT259180 Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
97 INT259181 Phosphorylation of Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
98 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
99 INT309126 Edc4 Positive_regulation of Akt1 1 0.02 0.99 0.47
100 INT309144 Dlat Positive_regulation of Akt1 1 0.03 0.99 0.47
101 INT276207 Binding of Akt1 and Myo1f 1 0.11 0.05 0.47
102 INT162932 TXNRD1 Negative_regulation of Phosphorylation of AKT1 1 0.14 1.01 0.47
103 INT114065 Akt1 Regulation of Gene_expression of Insr 1 0.13 0.28 0.46
104 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
105 INT95469 P2ry6 Positive_regulation of Positive_regulation of Pdpk1 1 0.15 0 0.46
106 INT162929 NQO1 Negative_regulation of Phosphorylation of AKT1 1 0.41 1 0.46
107 INT139900 Kcne2 Positive_regulation of Akt1 1 0.06 2.95 0.44
108 INT15024 Prkcg Regulation of Pdpk1 1 0.09 0 0.43
109 INT151184 Pdpk1 Positive_regulation of Trpv1 1 0.08 0 0.42
110 INT151183 Pdpk1 Positive_regulation of Phosphorylation of Trpv1 1 0.08 0 0.42
111 INT160047 PTEN Regulation of Gene_expression of AKT1 1 0.33 0.6 0.42
112 INT348785 Ins1 Positive_regulation of Phosphorylation of Akt1 1 0.17 3.5 0.42
113 INT322396 Hist1h1t Positive_regulation of Akt1 1 0.01 0 0.42
114 INT160048 INPPL1 Regulation of Gene_expression of AKT1 1 0.28 0.6 0.42
115 INT322395 Akt1 Regulation of Pik3cb 1 0.08 0 0.42
116 INT121851 AKT1 Regulation of ROS1 1 0.16 0.52 0.41
117 INT122749 Cyp3a23/3a1 Positive_regulation of Phosphorylation of Akt1 1 0.07 0.24 0.41
118 INT121848 AKT1 Regulation of CASP8 1 0.18 0.52 0.41
119 INT121854 AKT1 Regulation of BID 1 0.17 0.52 0.41
120 INT276216 Binding of Akt1 and Ins1 2 0.03 2.61 0.4
121 INT108197 AKT1 Regulation of JUN 1 0.29 0.25 0.4
122 INT231842 Pcdh8 Positive_regulation of Akt1 1 0.00 1.59 0.4
123 INT121853 Gene_expression of ROS1 Negative_regulation of AKT1 1 0.25 0.49 0.4
124 INT322409 Positive_regulation of OPRM1 Positive_regulation of Phosphorylation of Akt1 1 0.04 0 0.4
125 INT166155 Ccr9 Positive_regulation of Akt1 1 0.58 2.14 0.39
126 INT236111 Binding of Pdpk1 and Ppara 1 0.26 1.21 0.39
127 INT146611 Ins1 Positive_regulation of Phosphorylation of Akt1 9 0.23 4.34 0.37
128 INT89386 INS Positive_regulation of Phosphorylation of AKT1 3 0.43 1.48 0.36
129 INT299288 AKT1 Positive_regulation of RPTOR 1 0.34 0.05 0.36
130 INT112617 Pdpk1 Regulation of Il1b 1 0.03 1.11 0.36
131 INT112618 Pdpk1 Regulation of Tnf 1 0.03 1.11 0.36
132 INT148243 Binding of Akt1 and Kit 1 0.03 0.44 0.35
133 INT122758 Positive_regulation of Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
134 INT288208 Binding of Mapk14 and Positive_regulation of Akt1 1 0.01 0.42 0.35
135 INT176135 AKT1 Regulation of Localization of CYCS 1 0.43 2.16 0.35
136 INT122756 Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
137 INT309118 Dlat Positive_regulation of Positive_regulation of Akt1 1 0.03 0.32 0.34
138 INT249019 Gabrg1 Positive_regulation of Akt1 1 0.02 0 0.34
139 INT196820 Negative_regulation of Ppp1cc Positive_regulation of Akt1 1 0.00 0 0.34
140 INT89381 INS Positive_regulation of AKT1 6 0.43 3.06 0.33
141 INT222721 Binding of HTR1A and Pdpk1 1 0.00 0.35 0.33
142 INT214377 Akt1 Regulation of Amph 1 0.15 0 0.33
143 INT165580 Binding of Akt1 and Grin2b 1 0.02 0.2 0.32
144 INT337410 AKT3 Negative_regulation of AKT1 1 0.09 0.49 0.32
145 INT337414 AKT2 Negative_regulation of AKT1 1 0.10 0.5 0.32
146 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31
147 INT303063 Akt1 Negative_regulation of Gene_expression of Syn1 1 0.09 0.45 0.31
148 INT165921 Tlr4 Positive_regulation of Akt1 1 0.16 0.75 0.31
149 INT165920 Negative_regulation of Tlr4 Positive_regulation of Akt1 1 0.13 0.75 0.31
150 INT299307 AKT1 Positive_regulation of Positive_regulation of AKT1S1 1 0.10 0 0.3
151 INT299289 AKT1 Positive_regulation of Positive_regulation of TSC2 1 0.17 0 0.3
152 INT122575 Akt1 Positive_regulation of Phosphorylation of Nos3 4 0.37 3.89 0.29
153 INT291202 Positive_regulation of INS Positive_regulation of AKT1 1 0.01 0.76 0.29
154 INT132367 Lgals1 Positive_regulation of Akt1 1 0.22 0.13 0.28
155 INT317533 Akt1 Positive_regulation of Nos1 1 0.43 0 0.28
156 INT149322 Amph Positive_regulation of Akt1 1 0.39 0 0.27
157 INT18994 Negative_regulation of Pdpk1 Negative_regulation of Regulation of Cck 1 0.10 0 0.26
158 INT223930 Binding of Akt1 and Pik3cb 1 0.07 0.35 0.26
159 INT223929 Negative_regulation of Binding of Akt1 and Pik3cb 1 0.08 0.36 0.26
160 INT303082 Akt1 Negative_regulation of Gene_expression of Mafk 1 0.20 0.37 0.26
161 INT308661 Akt1 Positive_regulation of Chuk 1 0.02 0.6 0.25
162 INT314047 THL Negative_regulation of Phosphorylation of Akt1 1 0.14 0.71 0.25
163 INT326094 Akt1 Positive_regulation of Gene_expression of Gopc 1 0.03 0.49 0.24
164 INT326092 Gene_expression of Akt1 Negative_regulation of Gopc 1 0.03 0.55 0.24
165 INT326093 Akt1 Positive_regulation of Gopc 1 0.03 0.43 0.23
166 INT265886 IGF1 Positive_regulation of AKT1 1 0.11 3.06 0.23
167 INT323173 THRA Positive_regulation of Phosphorylation of Akt1 1 0.00 0 0.22
168 INT260844 NRP2 Positive_regulation of Akt1 1 0.00 0.73 0.22
169 INT116467 Vegfa Positive_regulation of Akt1 1 0.33 1.41 0.21
170 INT323174 DBT Positive_regulation of Phosphorylation of Akt1 1 0.01 0 0.21
171 INT120716 Binding of AKT1 and TEP1 1 0.05 0.46 0.21
172 INT116468 VEGFA Positive_regulation of Akt1 1 0.04 1.39 0.21
173 INT289356 Binding of Akt1 and Fgf2 1 0.03 0.82 0.21
174 INT309661 C5 Positive_regulation of Phosphorylation of Akt1 1 0.51 0.45 0.21
175 INT221237 Prkca Regulation of Phosphorylation of Akt1 1 0.01 0.28 0.2
176 INT224688 Pten Regulation of Akt1 1 0.04 1.12 0.19
177 INT58006 DYT10 Positive_regulation of Positive_regulation of Pdpk1 1 0.02 0.14 0.18
178 INT334631 Igf1r Positive_regulation of Phosphorylation of Akt1 1 0.19 0.5 0.18
179 INT303058 Akt1 Negative_regulation of Gene_expression of Syt1 1 0.21 0.43 0.18
180 INT221231 Pdpk1 Positive_regulation of Akt1 1 0.09 0.13 0.18
181 INT221244 Pdpk1 Positive_regulation of Phosphorylation of Akt1 1 0.09 0.13 0.18
182 INT298192 EGFR Positive_regulation of AKT1 1 0.10 0.65 0.18
183 INT121582 AKT1 Regulation of Gene_expression of GDF15 1 0.21 0.4 0.18
184 INT318324 Binding of AKT1 and PRKCA 1 0.03 0.63 0.18
185 INT253129 Ins1 Regulation of Phosphorylation of Akt1 3 0.11 1.66 0.17
186 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17
187 INT179841 Il11 Regulation of Positive_regulation of Akt1 1 0.08 0.07 0.17
188 INT105334 PTGER1 Positive_regulation of Positive_regulation of AKT1 1 0.05 0.66 0.17
189 INT282858 Bpifa2 Negative_regulation of Akt1 1 0.05 0.91 0.17
190 INT176134 AKT1 Regulation of Gene_expression of BIRC3 1 0.08 1.09 0.17
191 INT179849 Il11 Regulation of Positive_regulation of Pdpk1 1 0.05 0.07 0.17
192 INT226209 Pik3cb Positive_regulation of Phosphorylation of Akt1 1 0.10 1.16 0.17
193 INT282861 Bpifa2 Negative_regulation of Phosphorylation of Akt1 1 0.05 0.91 0.17
194 INT161547 Trpv1 Regulation of Sorbs1 1 0.03 0.25 0.17
195 INT218937 Akt1 Positive_regulation of Parn 1 0.01 0.65 0.16
196 INT316484 Akt1 Positive_regulation of Positive_regulation of Stat3 1 0.01 0.87 0.16
197 INT343475 Epo Regulation of Akt1 1 0.18 0.41 0.16
198 INT178079 EDN1 Positive_regulation of Positive_regulation of AKT1 1 0.05 0.91 0.16
199 INT343478 Epo Regulation of Gene_expression of Akt1 1 0.40 0.41 0.16
200 INT218930 Akt1 Positive_regulation of Xiap 1 0.06 0.64 0.16

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of establishment of protein localization in plasma membrane. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of establishment of protein localization in plasma membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
2 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
3 INT1232 Positive_regulation of Pdpk1 78 0.42 24.33 50.17
4 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
5 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
6 INT18992 Negative_regulation of Pdpk1 53 0.42 19.02 40.95
7 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
8 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
9 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
10 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
11 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
12 INT48769 Regulation of Pdpk1 20 0.35 9.78 20.36
13 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61
14 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44
15 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59
16 INT26733 Gene_expression of Pdpk1 17 0.48 5.74 13.91
17 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
18 INT74838 Positive_regulation of Sorbs1 18 0.34 6.93 12.63
19 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54
20 INT8533 Regulation of Sorbs1 9 0.27 3.01 11.98
21 INT26534 Regulation of Akt1 34 0.61 14.47 11.86
22 INT5630 Localization of Pdpk1 10 0.45 5.21 11.36
23 INT75137 Regulation of Akt1 74 0.48 37.89 9.7
24 INT8535 Localization of Sorbs1 9 0.80 2.71 9.07
25 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98
26 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69
27 INT72539 Gene_expression of Sorbs1 10 0.78 4.98 8.14
28 INT104013 Negative_regulation of Gene_expression of Pdpk1 4 0.31 2.36 7.89
29 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83
30 INT103925 Negative_regulation of Positive_regulation of Akt1 32 0.58 15.19 7.39
31 INT126748 Positive_regulation of Positive_regulation of Akt1 26 0.55 11.15 7.08
32 INT71824 Phosphorylation of Pdpk1 14 0.38 4.9 6.86
33 INT117721 Positive_regulation of Gene_expression of Akt1 22 0.69 6.26 6.08
34 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06
35 INT55077 Positive_regulation of Positive_regulation of Pdpk1 6 0.26 1.77 5.78
36 INT68465 Positive_regulation of Gene_expression of Pdpk1 7 0.19 2.35 5.49
37 INT105336 Regulation of AKT1 52 0.56 32.53 4.89
38 INT134657 Localization of Akt1 37 0.68 11.58 4.62
39 INT72538 Negative_regulation of Sorbs1 7 0.59 4.49 4.61
40 INT122569 Negative_regulation of Gene_expression of Akt1 34 0.54 17.15 4.44
41 INT109450 Positive_regulation of Phosphorylation of AKT1 62 0.64 25.18 4.21
42 INT75136 Binding of Akt1 27 0.27 8.81 4.15
43 INT1231 Negative_regulation of Positive_regulation of Pdpk1 6 0.35 1.88 4.13
44 INT139898 Negative_regulation of Positive_regulation of Akt1 15 0.42 4.66 4.06
45 INT132223 Negative_regulation of Negative_regulation of Akt1 6 0.42 2.75 3.66
46 INT136692 Localization of Akt1 12 0.78 2.14 3.65
47 INT8536 Binding of Sorbs1 2 0.14 1.24 3.64
48 INT157687 Regulation of Gene_expression of Akt1 9 0.62 4.96 3.27
49 INT108203 Negative_regulation of Gene_expression of AKT1 28 0.54 16.38 3.19
50 INT117720 Negative_regulation of Gene_expression of Akt1 11 0.37 2.33 3.08
51 INT89392 Negative_regulation of Positive_regulation of AKT1 23 0.50 15.69 3.02
52 INT89401 Negative_regulation of Phosphorylation of AKT1 68 0.58 35.61 2.8
53 INT117715 Regulation of Phosphorylation of Akt1 15 0.51 3.23 2.78
54 INT47846 Negative_regulation of Localization of Pdpk1 2 0.33 1.12 2.75
55 INT96763 Positive_regulation of Localization of Pdpk1 1 0.39 2.08 2.65
56 INT214355 Binding of Akt1 13 0.36 3.72 2.59
57 INT122060 Positive_regulation of Positive_regulation of Sorbs1 2 0.34 0.06 2.57
58 INT122424 Gene_expression of Prkci 1 0.58 0 2.56
59 INT118791 Binding of AKT1 32 0.48 15.51 2.25
60 INT138286 Regulation of Positive_regulation of Akt1 13 0.45 4.93 2.22
61 INT8537 Negative_regulation of Regulation of Sorbs1 1 0.18 0 2.17
62 INT101866 Positive_regulation of Gene_expression of AKT1 49 0.52 17.47 2.14
63 INT122423 Negative_regulation of Gene_expression of Prkci 1 0.43 0 2.04
64 INT26735 Regulation of Gene_expression of Pdpk1 2 0.24 0.56 1.84
65 INT123130 Positive_regulation of Positive_regulation of AKT1 22 0.49 11.77 1.83
66 INT142236 Regulation of Phosphorylation of Akt1 13 0.61 5.02 1.75
67 INT104014 Negative_regulation of Phosphorylation of Pdpk1 2 0.23 0.59 1.72
68 INT165332 Negative_regulation of Negative_regulation of Akt1 5 0.42 3.27 1.7
69 INT117714 Regulation of Positive_regulation of Akt1 3 0.61 0.44 1.61
70 INT67464 Positive_regulation of Negative_regulation of Pdpk1 1 0.19 0.15 1.41
71 INT118927 Positive_regulation of Phosphorylation of Pdpk1 2 0.04 0.76 1.38
72 INT180763 Positive_regulation of Binding of Sorbs1 1 0.02 1.25 1.26
73 INT180762 Negative_regulation of Binding of Sorbs1 1 0.02 1.24 1.26
74 INT221206 Phosphorylation of Pdpk1 3 0.53 0.13 1.25
75 INT167409 Regulation of Gene_expression of AKT1 8 0.56 4.86 1.23
76 INT104011 Transcription of Pdpk1 1 0.28 0 1.2
77 INT104012 Regulation of Transcription of Pdpk1 1 0.14 0 1.2
78 INT26734 Binding of Pdpk1 4 0.29 1.01 1.19
79 INT135556 Localization of AKT1 38 0.69 12.78 1.17
80 INT118792 Regulation of Positive_regulation of AKT1 8 0.61 3.73 1.15
81 INT176147 Regulation of Phosphorylation of AKT1 14 0.41 6.41 1.13
82 INT207203 Transcription of Akt1 6 0.67 3.73 1.1
83 INT191050 Positive_regulation of Negative_regulation of Akt1 6 0.31 1.82 1.03
84 INT122421 Phosphorylation of Prkci 1 0.47 0 1.02
85 INT68467 Regulation of Regulation of Pdpk1 1 0.05 0.09 0.96
86 INT134660 Positive_regulation of Localization of Akt1 10 0.32 6.33 0.94
87 INT162167 Negative_regulation of Gene_expression of ARF6 1 0.38 0 0.94
88 INT163508 Regulation of Gene_expression of Akt1 3 0.45 1.65 0.92
89 INT162168 Gene_expression of ARF6 1 0.68 0 0.92
90 INT266561 Negative_regulation of Positive_regulation of Sorbs1 1 0.01 1.01 0.88
91 INT151170 Regulation of Regulation of Akt1 2 0.45 3.28 0.73
92 INT153565 Gene_expression of PRKCI 1 0.75 0 0.72
93 INT299338 Negative_regulation of Regulation of AKT1 2 0.31 2.32 0.68
94 INT207204 Regulation of Transcription of Akt1 3 0.35 1.41 0.66
95 INT166024 Protein_catabolism of AKT1 5 0.46 2.6 0.64
96 INT281466 Negative_regulation of Regulation of Akt1 1 0.33 0.31 0.63
97 INT153568 Binding of PRKCI 1 0.36 0 0.6
98 INT123131 Negative_regulation of Negative_regulation of AKT1 6 0.42 3.23 0.58
99 INT122420 Regulation of Prkci 1 0.44 0 0.58
100 INT79249 Regulation of Negative_regulation of Pdpk1 1 0.03 0.09 0.57
101 INT218900 Regulation of Negative_regulation of Akt1 3 0.15 1.73 0.53
102 INT98037 Negative_regulation of Negative_regulation of Pdpk1 1 0.05 0.26 0.52
103 INT276189 Regulation of Localization of Akt1 1 0.43 0.2 0.5
104 INT323479 Phosphorylation of Sorbs1 1 0.06 1.8 0.49
105 INT30080 Binding of Arhgef16 1 0.11 0.54 0.45
106 INT34037 Regulation of Arhgef16 1 0.15 0.6 0.45
107 INT235660 Gene_expression of EPHA2 27 0.75 23.46 0.4
108 INT102722 Phosphorylation of PDPK1 3 0.82 1.39 0.4
109 INT236107 Binding of Pdpk1 2 0.26 1.38 0.39
110 INT236105 Negative_regulation of Binding of Pdpk1 1 0.30 1.22 0.39
111 INT254484 Positive_regulation of Gene_expression of Sorbs1 4 0.12 1.9 0.37
112 INT235655 Positive_regulation of Gene_expression of EPHA2 14 0.67 13.48 0.35
113 INT179816 Positive_regulation of Pdpk1 4 0.31 0.36 0.35
114 INT235658 Positive_regulation of EPHA2 4 0.67 3.42 0.32
115 INT321348 Positive_regulation of Localization of Akt1 1 0.30 0.08 0.32
116 INT238439 Positive_regulation of PDPK1 2 0.20 1.3 0.31
117 INT239464 Regulation of Negative_regulation of Akt1 3 0.31 0.37 0.25
118 INT102717 Gene_expression of PDPK1 1 0.77 3.11 0.25
119 INT102719 Negative_regulation of PDPK1 1 0.58 3 0.21
120 INT200666 Transcription of AKT1 8 0.66 4.23 0.2
121 INT230483 Protein_catabolism of Akt1 2 0.10 1.11 0.2
122 INT352913 Regulation of EPHA2 1 0.05 0.74 0.2
123 INT276192 Transcription of Akt1 1 0.66 0.47 0.18
124 INT176153 Regulation of Negative_regulation of AKT1 3 0.39 2.13 0.16
125 INT135557 Positive_regulation of Localization of AKT1 3 0.46 0.49 0.15
126 INT226185 Protein_catabolism of Akt1 7 0.53 2.43 0.14
127 INT302248 Negative_regulation of Binding of AKT1 2 0.25 1 0.14
128 INT285902 Positive_regulation of Transcription of AKT1 1 0.06 0.6 0.13
129 INT102720 Positive_regulation of Gene_expression of PDPK1 1 0.69 1.61 0.13
130 INT214360 Negative_regulation of Binding of Akt1 2 0.41 0.09 0.12
131 INT236109 Localization of Pdpk1 1 0.49 0.75 0.12
132 INT355216 Positive_regulation of Binding of Akt1 1 0.37 0.35 0.12
133 INT199082 Positive_regulation of Binding of Akt1 4 0.17 1.25 0.11
134 INT192239 Positive_regulation of Binding of AKT1 2 0.26 0.91 0.08
135 INT102718 Negative_regulation of Phosphorylation of PDPK1 1 0.43 0.83 0.08
136 INT302629 Positive_regulation of Rhog 1 0.33 0.07 0.07
137 INT104656 Regulation of Phosphorylation of Pdpk1 1 0.05 1.74 0.07
138 INT307475 Positive_regulation of Negative_regulation of Akt1 1 0.12 0.12 0.07
139 INT243988 Binding of Nrxn1 1 0.01 0.21 0.07
140 INT182302 Negative_regulation of Localization of AKT1 5 0.39 3.52 0.06
141 INT120564 Gene_expression of Pdpk1 2 0.62 1.54 0.06
142 INT209184 Regulation of PRKCI 1 0.02 0.06 0.06
143 INT243932 Gene_expression of Nrxn1 1 0.02 0.28 0.06
144 INT120565 Positive_regulation of Gene_expression of Pdpk1 1 0.40 1.26 0.06
145 INT302628 Gene_expression of Rhog 1 0.45 0.2 0.05
146 INT236706 Regulation of Pdpk1 1 0.12 0.38 0.04
147 INT300989 Positive_regulation of Negative_regulation of AKT1 2 0.41 1.27 0.03
148 INT288183 Positive_regulation of Regulation of Akt1 1 0.05 0.06 0.03
149 INT336399 Transcription of EPHA2 1 0.24 2.21 0.03
150 INT235654 Binding of EPHA2 5 0.36 4.26 0
151 INT268244 Negative_regulation of Localization of Akt1 2 0.28 2 0
152 INT173193 Binding of SORBS1 2 0.14 1.29 0
153 INT293479 Positive_regulation of Protein_catabolism of Akt1 1 0.26 0.53 0
154 INT331203 Positive_regulation of Binding of Pdpk1 1 0.15 0.17 0
155 INT273545 Negative_regulation of Epha2 1 0.28 0.08 0
156 INT340543 Regulation of Binding of Akt1 1 0.23 0.18 0
157 INT230480 Positive_regulation of Protein_catabolism of Akt1 1 0.06 0.75 0
158 INT198028 Regulation of Regulation of AKT1 1 0.22 1.08 0
159 INT189989 Negative_regulation of Pdpk1 1 0.08 1.48 0
160 INT223603 Regulation of Localization of AKT1 1 0.23 0.65 0
161 INT339743 Positive_regulation of SORBS1 1 0.06 0.39 0
162 INT235652 Localization of EPHA2 1 0.72 0.89 0
163 INT300629 Transcription of Epha2 1 0.22 1.11 0
164 INT200688 Negative_regulation of Transcription of AKT1 1 0.54 1.53 0
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