GO:0090009

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Name primitive streak formation
Categary Process
Go Slim No
Go Link GO:0090009
Unique Molecular Interactions 33
Total Molecular Interactions 40
Total Single Events 168
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for primitive streak formation. They are ordered first by their pain relevance and then by number of times they were reported for primitive streak formation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT324224 Binding of OTX2 and H9 1 0.11 0.17 0.33
2 INT93833 Binding of Fos and Srf 1 0.00 0 0.3
3 INT93832 Binding of Elk1 and Srf 1 0.00 0 0.29
4 INT162599 Wnt5a Regulation of Gene_expression of IL4I1 1 0.00 0.1 0.28
5 INT287884 WNT5A Positive_regulation of THEMIS 1 0.00 0.08 0.13
6 INT280484 Bdnf Positive_regulation of Gene_expression of Lhx1 1 0.48 1.49 0.11
7 INT309371 Lhx1 Positive_regulation of Gene_expression of Pax2 1 0.08 0.07 0.11
8 INT233510 Wnt5a Positive_regulation of Gene_expression of Il12a 1 0.03 0.33 0.1
9 INT211960 Wnt5a Positive_regulation of Car2 1 0.13 0.38 0.08
10 INT287879 Binding of WNT5A and FZD5 1 0.06 1.16 0.08
11 INT216130 SRF Positive_regulation of Gene_expression of EGR1 1 0.49 0.32 0.07
12 INT216129 SRF Positive_regulation of Gene_expression of FOS 1 0.28 0.32 0.07
13 INT319558 Positive_regulation of Creb1 Regulation of Srf 1 0.31 0.06 0.04
14 INT319559 Creb1 Regulation of Srf 1 0.28 0.06 0.04
15 INT262169 Binding of Foxa2 and Nr1i2 1 0.17 0.33 0
16 INT262183 Foxa2 Positive_regulation of Gene_expression of Hmgcs2 1 0.10 0.22 0
17 INT132849 Homer1 Regulation of Srf 1 0.01 0.15 0
18 INT302321 Negative_regulation of Binding of Lrp6 and SOST 1 0.16 0.26 0
19 INT190632 Binding of Srf and Yy1 1 0.20 0.14 0
20 INT335884 Akt1 Regulation of Positive_regulation of Wnt5a 1 0.03 0.15 0
21 INT269954 Sox17 Regulation of Gene_expression of Foxa2 1 0.43 0 0
22 INT302320 Binding of Lrp6 and SOST 1 0.18 0.26 0
23 INT269933 Foxa2 Regulation of Gene_expression of Foxj1 1 0.27 0 0
24 INT185453 Binding of PRKCB and Lhx1 1 0.35 1.99 0
25 INT225590 Ncoa6 Regulation of Srf 1 0.08 0.21 0
26 INT335887 Akt1 Regulation of Lrp6 1 0.06 0.15 0
27 INT244857 Lbx1 Positive_regulation of Lhx1 1 0.37 0 0
28 INT335883 Binding of Lrp6 and Wnt5a 1 0.27 0.08 0
29 INT269927 Foxa2 Regulation of Gene_expression of Scgb1a1 1 0.26 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for primitive streak formation. They are ordered first by their pain relevance and then by number of times they were reported in primitive streak formation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4114 Gene_expression of Srf 9 0.70 6.11 2.63
2 INT10447 Negative_regulation of Srf 3 0.40 0.95 1.98
3 INT108519 Binding of Lrp6 8 0.44 1.47 1.19
4 INT150074 Gene_expression of WNT5A 8 0.75 6.3 1.17
5 INT10448 Positive_regulation of Srf 3 0.47 0.89 1.03
6 INT135032 Negative_regulation of SRF 1 0.49 0 1.03
7 INT26531 Regulation of Srf 3 0.18 0.62 0.9
8 INT45293 Transcription of Srf 2 0.47 0.79 0.76
9 INT45489 Gene_expression of SRF 5 0.77 3.29 0.71
10 INT150075 Positive_regulation of Gene_expression of WNT5A 2 0.67 2.53 0.59
11 INT45292 Negative_regulation of Transcription of Srf 1 0.06 0.65 0.59
12 INT216363 Gene_expression of OTX2 4 0.54 0.32 0.55
13 INT18821 Positive_regulation of Gene_expression of Srf 2 0.35 0.63 0.31
14 INT185428 Gene_expression of Lhx1 4 0.75 2.6 0.28
15 INT7610 Localization of Srf 3 0.67 0.98 0.27
16 INT335875 Regulation of Lrp6 1 0.57 0.43 0.27
17 INT185427 Negative_regulation of Lhx1 4 0.42 3.48 0.17
18 INT335861 Localization of Lrp6 1 0.69 0.54 0.17
19 INT89766 Binding of SRF 1 0.17 0.89 0.15
20 INT89767 Positive_regulation of Binding of SRF 1 0.23 0.89 0.15
21 INT162574 Gene_expression of Wnt5a 7 0.47 0.92 0.1
22 INT282594 Localization of WNT5A 2 0.18 0.89 0.1
23 INT233483 Regulation of Gene_expression of Wnt5a 1 0.19 0.33 0.1
24 INT162576 Positive_regulation of Wnt5a 3 0.48 0.71 0.08
25 INT22789 Binding of Srf 1 0.37 0.07 0.07
26 INT290078 Regulation of WNT5A 1 0.07 2.3 0.07
27 INT22790 Positive_regulation of Binding of Srf 1 0.50 0.07 0.07
28 INT190544 Transcription of Srf 1 0.19 0.43 0.06
29 INT190570 Localization of Srf 1 0.20 0.49 0.06
30 INT335865 Positive_regulation of Phosphorylation of Lrp6 1 0.64 0.46 0.05
31 INT335862 Phosphorylation of Lrp6 1 0.76 0.37 0.05
32 INT185429 Regulation of Lhx1 1 0.12 1.33 0.04
33 INT225411 Positive_regulation of Srf 1 0.05 0.27 0.03
34 INT268102 Transcription of SRF 1 0.53 0.85 0.03
35 INT225413 Binding of Srf 1 0.10 0.27 0.03
36 INT157800 Gene_expression of Srf 2 0.45 0.88 0
37 INT200834 Positive_regulation of Foxa2 2 0.32 0.08 0
38 INT105753 Positive_regulation of Gene_expression of SRF 1 0.01 0.13 0
39 INT185426 Binding of Lhx1 1 0.36 1.96 0
40 INT335872 Positive_regulation of Gene_expression of Lrp6 1 0.46 0.18 0
41 INT335880 Regulation of Wnt5a 1 0.32 0.07 0
42 INT262045 Phosphorylation of Foxa2 1 0.34 0.08 0
43 INT282947 Negative_regulation of OTX2 1 0.35 0 0
44 INT105752 Positive_regulation of SRF 1 0.01 0.13 0
45 INT324222 Binding of OTX2 1 0.20 0 0
46 INT268104 Negative_regulation of Gene_expression of SRF 1 0.38 0.16 0
47 INT213446 Regulation of Gene_expression of SRF 1 0.22 0.71 0
48 INT262071 Binding of Foxa2 1 0.15 0.68 0
49 INT347117 Negative_regulation of Binding of Lrp6 1 0.28 0.5 0
50 INT335866 Regulation of Transcription of Lrp6 1 0.42 0.25 0
51 INT262084 Negative_regulation of Binding of Foxa2 1 0.18 0.23 0
52 INT162572 Positive_regulation of Gene_expression of Wnt5a 1 0.02 0.3 0
53 INT225408 Negative_regulation of Srf 1 0.05 0.39 0
54 INT157799 Negative_regulation of Gene_expression of Srf 1 0.18 0.07 0
55 INT262125 Negative_regulation of Foxa2 1 0.18 0.08 0
56 INT157794 Phosphorylation of Srf 1 0.26 0.07 0
57 INT335881 Gene_expression of Lrp6 1 0.62 0.09 0
58 INT269888 Gene_expression of Foxa2 1 0.65 0 0
59 INT335873 Transcription of Lrp6 1 0.64 0.25 0
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