GO:0090102

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Name cochlea development
Categary Process
Go Slim No
Go Link GO:0090102
Unique Molecular Interactions 57
Total Molecular Interactions 65
Total Single Events 435
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cochlea development. They are ordered first by their pain relevance and then by number of times they were reported for cochlea development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT112033 Gabrb3 Positive_regulation of Plcg1 1 0.05 0.18 1.49
2 INT112034 Gabrb3 Positive_regulation of Pik3r1 1 0.08 0.18 1.48
3 INT292988 Negative_regulation of SGCG Positive_regulation of GABRB3 1 0.01 0.3 0.89
4 INT292990 SGCG Positive_regulation of Gene_expression of GABRB3 1 0.01 0.29 0.87
5 INT292989 SGCG Positive_regulation of GABRB3 1 0.01 0.29 0.87
6 INT285656 Cnrip1 Negative_regulation of Kcnk3 1 0.00 0.23 0.85
7 INT309366 Pax2 Negative_regulation of Transcription of Slc6a5 1 0.03 0 0.31
8 INT309369 Ptf1a Positive_regulation of Pax2 1 0.10 0 0.3
9 INT122311 Sst Regulation of Kcnk3 1 0.14 0.28 0.29
10 INT122312 Prkaca Regulation of Kcnk3 1 0.13 0.28 0.28
11 INT356231 Binding of Gabrb3 and Gad1 1 0.32 1.25 0.23
12 INT274005 KCNK3 Positive_regulation of SYNM 1 0.06 0 0.23
13 INT52459 Binding of SUCLA2 and HEY2 1 0.01 0.09 0.21
14 INT297545 Pou3f3 Regulation of Hes1 1 0.05 0.41 0.2
15 INT328143 Gabrb3 Positive_regulation of Ube3a 1 0.56 0.99 0.11
16 INT309371 Lhx1 Positive_regulation of Gene_expression of Pax2 1 0.08 0.07 0.11
17 INT309372 Lhx5 Positive_regulation of Gene_expression of Pax2 1 0.09 0.07 0.11
18 INT328146 Gabrb3 Negative_regulation of Ube3a 1 0.48 0.99 0.11
19 INT297548 Neurod1 Regulation of Hes1 1 0.05 0.2 0.1
20 INT23780 Ntrk3 Positive_regulation of Localization of Prl 1 0.11 0 0.08
21 INT250865 Binding of Fgf8 and Fgfr3 1 0.18 0.3 0.05
22 INT264735 Binding of Hes1 and Mir199b 1 0.08 0.93 0
23 INT244839 Lbx1 Positive_regulation of Pax2 1 0.39 0 0
24 INT264738 Mir199b Regulation of Gene_expression of Hes1 1 0.08 0.89 0
25 INT264736 Hes1 Regulation of Notch2 1 0.20 0.13 0
26 INT197316 Hes1 Regulation of Atoh1 1 0.01 0.14 0
27 INT240723 Atp2b2 Positive_regulation of Localization of Ca2 1 0.11 0.43 0
28 INT197304 Ahr Regulation of Hes1 1 0.06 0.17 0
29 INT264731 Gene_expression of Hes1 Negative_regulation of Positive_regulation of Musd1 1 0.00 0.18 0
30 INT240724 Atp2b2 Positive_regulation of Ca2 1 0.11 0.54 0
31 INT328141 Binding of Chrne and Gabrb3 1 0.41 0.08 0
32 INT297691 Binding of Fut1 and Pax2 1 0.03 0 0
33 INT264729 Mir199b Regulation of Hes1 1 0.05 0.25 0
34 INT301366 Fgf18 Positive_regulation of Fgfr3 1 0.04 0.34 0
35 INT197310 Hes1 Regulation of Ascl1 1 0.01 0.14 0
36 INT264725 Binding of Hes1 and Notch1 1 0.03 0.84 0
37 INT264734 Mir199b Negative_regulation of Negative_regulation of Hes1 1 0.07 0.1 0
38 INT264739 Mir199b Negative_regulation of Gene_expression of Hes1 1 0.07 0.82 0
39 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0
40 INT264733 Hes1 Regulation of Mir199b 1 0.05 0.43 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cochlea development. They are ordered first by their pain relevance and then by number of times they were reported in cochlea development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT21132 Gene_expression of GABRB3 36 0.33 11.32 17.61
2 INT67116 Gene_expression of Ntrk3 20 0.59 7.64 8.94
3 INT73114 Gene_expression of Kcnk3 32 0.77 1.57 4.03
4 INT183560 Binding of GABRB3 12 0.23 2.59 3.77
5 INT137532 Negative_regulation of HEY2 1 0.31 1.69 3.18
6 INT261712 Regulation of GABRB3 6 0.09 3.03 3.14
7 INT109496 Gene_expression of KCNK3 9 0.78 0.59 3.02
8 INT292993 Positive_regulation of Gene_expression of GABRB3 4 0.17 0.9 2.63
9 INT292992 Negative_regulation of Gene_expression of GABRB3 3 0.15 0.78 2.41
10 INT60156 Regulation of Kcnk3 7 0.42 2.47 2.4
11 INT74361 Negative_regulation of Gabrb3 4 0.58 0.73 2.28
12 INT21130 Positive_regulation of GABRB3 4 0.27 1.88 2.21
13 INT145539 Negative_regulation of KCNK3 3 0.59 0 2.07
14 INT73112 Negative_regulation of Kcnk3 7 0.58 1.2 1.55
15 INT74360 Gene_expression of Gabrb3 2 0.77 3.85 1.49
16 INT183557 Localization of GABRB3 3 0.46 1.01 1.34
17 INT13530 Negative_regulation of GABRB3 4 0.17 1.48 1.31
18 INT39503 Positive_regulation of KCNK3 3 0.47 0.09 1.29
19 INT90397 Positive_regulation of Kcnk3 3 0.68 1.31 1.29
20 INT145919 Regulation of KCNK3 5 0.62 0.09 1.22
21 INT292991 Negative_regulation of Localization of GABRB3 2 0.13 0.44 1.18
22 INT67117 Negative_regulation of Gene_expression of Ntrk3 1 0.30 0.24 0.96
23 INT67115 Transcription of Ntrk3 1 0.37 0.19 0.81
24 INT67118 Regulation of Gene_expression of Ntrk3 1 0.31 0.17 0.79
25 INT318278 Regulation of Gene_expression of GABRB3 1 0.14 0.47 0.77
26 INT82071 Regulation of Ntrk3 1 0.14 0.25 0.76
27 INT118469 Gene_expression of Fgfr3 5 0.72 6.98 0.75
28 INT264709 Gene_expression of Hes1 24 0.76 7.04 0.63
29 INT148385 Positive_regulation of HEY2 1 0.38 1.09 0.62
30 INT74362 Regulation of Gabrb3 1 0.28 0 0.58
31 INT86339 Positive_regulation of Gabrb3 1 0.14 0.14 0.51
32 INT147368 Negative_regulation of Regulation of Kcnk3 1 0.25 0.6 0.47
33 INT245016 Transcription of GABRB3 1 0.17 0 0.47
34 INT53282 Negative_regulation of Atp2b2 4 0.15 2.6 0.45
35 INT292608 Positive_regulation of Regulation of GABRB3 1 0.05 1.58 0.45
36 INT318270 Positive_regulation of Negative_regulation of GABRB3 1 0.11 0.09 0.36
37 INT213507 Gene_expression of Pax2 10 0.67 1.41 0.34
38 INT237469 Positive_regulation of Ntrk3 1 0.46 0.05 0.34
39 INT309354 Regulation of Pax2 1 0.10 0 0.29
40 INT309339 Negative_regulation of Localization of Pax2 1 0.15 0 0.28
41 INT328133 Localization of Gabrb3 1 0.75 1.35 0.27
42 INT318277 Phosphorylation of GABRB3 1 0.19 0.45 0.25
43 INT90398 Regulation of Gene_expression of Kcnk3 1 0.27 0 0.24
44 INT356219 Binding of Gabrb3 1 0.29 1.25 0.23
45 INT145920 Regulation of Gene_expression of KCNK3 1 0.27 0 0.22
46 INT274011 Positive_regulation of Positive_regulation of KCNK3 1 0.08 0 0.21
47 INT274012 Negative_regulation of Gene_expression of KCNK3 1 0.07 0.09 0.21
48 INT264701 Negative_regulation of Gene_expression of Hes1 1 0.42 0.73 0.18
49 INT328139 Negative_regulation of Gene_expression of Gabrb3 1 0.43 0.1 0.15
50 INT309352 Localization of Pax2 1 0.27 0 0.14
51 INT240716 Negative_regulation of Gene_expression of Atp2b2 1 0.09 0.78 0.1
52 INT240713 Gene_expression of Atp2b2 1 0.14 1.16 0.09
53 INT250839 Binding of Fgfr3 1 0.16 0.19 0.08
54 INT240714 Negative_regulation of Localization of Atp2b2 1 0.09 1.3 0.08
55 INT244741 Positive_regulation of Gene_expression of Pax2 1 0.38 0 0.06
56 INT240715 Localization of Atp2b2 1 0.16 1.07 0.04
57 INT264717 Negative_regulation of Hes1 7 0.42 0.77 0.03
58 INT264704 Regulation of Hes1 4 0.44 1.03 0.03
59 INT277248 Localization of HEY2 1 0.73 0.5 0.03
60 INT264702 Positive_regulation of Gene_expression of Hes1 1 0.68 1.39 0.03
61 INT264719 Regulation of Gene_expression of Hes1 2 0.28 0.12 0
62 INT276327 Positive_regulation of Gene_expression of Fgfr3 2 0.43 1.83 0
63 INT264708 Transcription of Hes1 1 0.67 0.83 0
64 INT243057 Positive_regulation of Fgfr3 1 0.46 0.79 0
65 INT303553 Regulation of Gene_expression of Fgfr3 1 0.25 0.3 0
66 INT244782 Negative_regulation of Pax2 1 0.44 0 0
67 INT328126 Positive_regulation of Gene_expression of Gabrb3 1 0.50 1.08 0
68 INT243058 Positive_regulation of Positive_regulation of Fgfr3 1 0.46 0.8 0
69 INT328138 Protein_catabolism of Gabrb3 1 0.88 0 0
70 INT118104 Transcription of Kcnk3 1 0.52 0.07 0
71 INT264705 Binding of Hes1 1 0.35 0.07 0
72 INT264706 Positive_regulation of Hes1 1 0.40 0.14 0
73 INT301359 Positive_regulation of Fgfr3 1 0.19 0.64 0
74 INT213529 Negative_regulation of Gene_expression of Pax2 1 0.37 0.23 0
75 INT301357 Negative_regulation of Positive_regulation of Fgfr3 1 0.16 0.35 0
76 INT341052 Gene_expression of HEY2 1 0.04 0.12 0
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