GO:0090181

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Name regulation of cholesterol metabolic process
Categary Process
Go Slim No
Go Link GO:0090181
Unique Molecular Interactions 39
Total Molecular Interactions 79
Total Single Events 275
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of cholesterol metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for regulation of cholesterol metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT128860 NR1H4 Negative_regulation of Gene_expression of OPRM1 1 0.15 0.31 0.92
2 INT177269 Binding of CXADR and NR1H4 1 0.04 0 0.58
3 INT5935 Por Regulation of Oprm1 1 0.19 0.51 0.28
4 INT173120 Binding of PPARA and NR1H4 8 0.09 2.79 0.23
5 INT278610 CDCA2 Negative_regulation of NR1H4 1 0.01 0.62 0.13
6 INT264403 NR1H4 Negative_regulation of IL1R2 1 0.04 0.09 0.12
7 INT177263 Binding of NR1H4 and FAUP1 1 0.00 0 0.09
8 INT238472 Binding of AVP and POR 1 0.02 0.85 0.09
9 INT342232 Binding of POR and SEPP1 1 0.02 0.75 0.08
10 INT177278 Binding of HLA-DRB4 and NR1H4 1 0.02 0 0.08
11 INT279416 NR1H4 Regulation of PPARA 1 0.01 0.13 0.08
12 INT177265 Binding of CYP3A4 and NR1H4 1 0.03 0 0.08
13 INT279421 Binding of NR1H4 and MLXIPL 1 0.00 0.27 0.07
14 INT177255 Binding of SV2A and NR1H4 1 0.04 0 0.07
15 INT182943 Binding of DR1 and NR1H4 3 0.03 0.14 0.06
16 INT113862 Binding of CA2 and NR1H4 1 0.00 0 0.06
17 INT113861 Binding of CA3 and NR1H4 1 0.00 0 0.06
18 INT177276 Positive_regulation of Binding of CXADR and NR1H4 1 0.04 0 0.05
19 INT177282 Regulation of Binding of CXADR and NR1H4 1 0.02 0 0.05
20 INT177270 Binding of TNFRSF25 and NR1H4 2 0.02 0.21 0.04
21 INT177272 Binding of ABCB1 and NR1H4 1 0.02 0 0.04
22 INT256418 PPARA Positive_regulation of NR1H4 1 0.01 1.17 0.04
23 INT264382 NR1H4 Positive_regulation of VDR 1 0.04 0.09 0.03
24 INT264396 NR1H4 Positive_regulation of THRA 1 0.01 0.09 0.03
25 INT182950 Binding of VDR and NR1H4 5 0.03 1.16 0
26 INT182924 Binding of RARA and NR1H4 3 0.02 1.9 0
27 INT290033 Binding of PPARD and NR1H4 1 0.01 0.39 0
28 INT264979 Binding of POR and BAG3 1 0.15 0.38 0
29 INT290027 Binding of PPARG and NR1H4 1 0.03 0.39 0
30 INT290029 Binding of INS and NR1H4 1 0.01 0.47 0
31 INT183014 Binding of NR1H4 and Dre 1 0.00 0.06 0
32 INT182955 Positive_regulation of Binding of VDR and NR1H4 1 0.03 0 0
33 INT302303 Binding of NR1H4 and Rdh5 1 0.02 0.11 0
34 INT330956 Binding of TEP1 and NR1H4 1 0.00 1.07 0
35 INT234439 Binding of NR1H4 and HCC 1 0.06 0.82 0
36 INT278605 CDCA2 Positive_regulation of NR1H4 1 0.01 0.36 0
37 INT182930 Binding of TNFRSF10B and NR1H4 1 0.02 0 0
38 INT135128 Binding of NR1I2 and NR1H4 1 0.09 0.57 0
39 INT182963 Binding of NR1H4 and KCNIP3 1 0.03 0.45 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of cholesterol metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in regulation of cholesterol metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132575 Binding of NR1H4 57 0.20 22.06 2.82
2 INT38384 Regulation of Por 5 0.47 0.58 2.4
3 INT12131 Gene_expression of POR 17 0.77 9.42 2.17
4 INT114953 Gene_expression of NR1H4 23 0.29 16.58 2.02
5 INT59302 Positive_regulation of POR 19 0.49 15.18 1.95
6 INT135132 Positive_regulation of NR1H4 17 0.30 8.63 1.38
7 INT151 Positive_regulation of Por 5 0.62 0.42 1.31
8 INT114961 Positive_regulation of Gene_expression of NR1H4 6 0.16 3.55 1.23
9 INT49013 Gene_expression of Por 6 0.75 2.19 1.22
10 INT115821 Transcription of Por 1 0.33 0.51 1.02
11 INT49012 Regulation of Gene_expression of Por 1 0.44 0 1.02
12 INT58960 Regulation of POR 5 0.25 1.04 0.68
13 INT40164 Binding of Por 2 0.37 0.5 0.51
14 INT265 Negative_regulation of Por 4 0.59 0.34 0.41
15 INT234463 Phosphorylation of NR1H4 23 0.34 14.56 0.39
16 INT12249 Binding of POR 5 0.35 2.76 0.35
17 INT234456 Negative_regulation of Gene_expression of NR1H4 2 0.18 1.05 0.32
18 INT12132 Positive_regulation of Gene_expression of POR 5 0.31 1.96 0.27
19 INT64189 Protein_catabolism of POR 1 0.37 0.16 0.18
20 INT234469 Negative_regulation of Phosphorylation of NR1H4 2 0.14 1.25 0.16
21 INT234464 Negative_regulation of NR1H4 6 0.19 3.54 0.12
22 INT115825 Positive_regulation of Gene_expression of Por 2 0.22 0.47 0.12
23 INT167018 Negative_regulation of POR 3 0.37 1.9 0.11
24 INT234468 Protein_catabolism of NR1H4 2 0.32 0.87 0.09
25 INT115833 Negative_regulation of Transcription of Por 1 0.20 0.52 0.09
26 INT115828 Negative_regulation of Gene_expression of Por 1 0.20 0.52 0.09
27 INT177318 Negative_regulation of Binding of NR1H4 5 0.14 3.39 0.08
28 INT234477 Localization of NR1H4 3 0.24 2.23 0.07
29 INT67606 Localization of POR 3 0.68 1.22 0.06
30 INT177301 Positive_regulation of Binding of NR1H4 3 0.29 0.45 0
31 INT234451 Positive_regulation of Phosphorylation of NR1H4 1 0.22 5.15 0
32 INT323616 Phosphorylation of POR 1 0.05 0.7 0
33 INT323617 Positive_regulation of Phosphorylation of POR 1 0.03 0.7 0
34 INT264980 Transcription of POR 1 0.38 0.73 0
35 INT234475 Transcription of NR1H4 1 0.17 1.62 0
36 INT234470 Positive_regulation of Protein_catabolism of NR1H4 1 0.22 0.93 0
37 INT264439 Regulation of Binding of NR1H4 1 0.19 0 0
38 INT191529 Negative_regulation of Positive_regulation of POR 1 0.02 1.5 0
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