GO:0090184

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Name positive regulation of kidney development
Categary Process
Go Slim No
Go Link GO:0090184
Unique Molecular Interactions 87
Total Molecular Interactions 126
Total Single Events 971
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of kidney development. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of kidney development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT31772 Ednra Positive_regulation of Nppa 1 0.05 0.13 1.33
2 INT172500 Ednra Positive_regulation of Coc 1 0.01 1 1.2
3 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
4 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97
5 INT123023 Ednra Regulation of Adarb1 1 0.00 0 0.93
6 INT123024 Csf2 Regulation of Ednra 1 0.06 0 0.92
7 INT128701 Ednra Regulation of EDNRB 1 0.17 0.58 0.84
8 INT128702 Ednra Regulation of EDNRA 1 0.00 0.58 0.84
9 INT134286 PLD2 Regulation of Regulation of EDNRA 1 0.10 0 0.67
10 INT219921 EDNRA Negative_regulation of Trpv1 1 0.13 0.36 0.63
11 INT219919 EDNRA Negative_regulation of Edn1 1 0.15 0.36 0.63
12 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62
13 INT230734 Negative_regulation of Binding of EDNRA and Pah 1 0.02 3.26 0.61
14 INT230735 Binding of EDNRA and Pah 1 0.02 3.22 0.6
15 INT278824 Positive_regulation of Binding of EDNRA and EDNRB 1 0.12 1.65 0.53
16 INT99571 Edn1 Positive_regulation of Localization of Ednra 1 0.01 0.32 0.47
17 INT219910 EDN1 Positive_regulation of Positive_regulation of EDNRA 1 0.00 0.3 0.45
18 INT94093 Pnoc Positive_regulation of EDNRA 1 0.03 0.1 0.44
19 INT334763 Ednra Positive_regulation of Gabrg1 1 0.01 0 0.4
20 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39
21 INT77683 Ednra Negative_regulation of LH 1 0.03 0.23 0.39
22 INT185530 Binding of AGT and EDNRA 1 0.00 0.31 0.38
23 INT80444 Binding of EDNRA and SPR 1 0.05 0.1 0.36
24 INT303030 Binding of Ednra and MCPH1 1 0.00 1.02 0.32
25 INT119603 H2-Ab1 Regulation of EDNRA 1 0.00 0.07 0.32
26 INT119602 EDNRA Regulation of H2-Ab1 1 0.00 0.07 0.32
27 INT303005 Binding of Ednra and Pah 1 0.06 1.02 0.32
28 INT69365 Binding of EDNRA and Pnoc 1 0.00 0 0.31
29 INT284137 EDNRB Regulation of EDNRA 1 0.07 0.09 0.3
30 INT117588 Binding of C5AR1 and EDNRA 1 0.40 0.38 0.3
31 INT178102 EDNRA Positive_regulation of Localization of TIMP1 1 0.06 0.97 0.28
32 INT178088 EDNRA Positive_regulation of Transcription of TIMP1 1 0.06 0.97 0.28
33 INT239226 Binding of Edn1 and Ednra 2 0.06 1.59 0.26
34 INT124117 Apcs Negative_regulation of Ednra 1 0.09 0 0.26
35 INT219918 Positive_regulation of EDNRA Positive_regulation of Trpv1 1 0.13 0 0.26
36 INT36875 Binding of EDNRA and SYNCRIP 1 0.01 0 0.24
37 INT284139 EDNRB Positive_regulation of Gene_expression of EDNRA 1 0.12 0.45 0.22
38 INT36876 EDNRA Regulation of Negative_regulation of PRB1 1 0.00 0 0.21
39 INT106825 Ednra Negative_regulation of Igf1 1 0.07 0.07 0.2
40 INT287894 VEGFA Positive_regulation of Localization of BMP4 1 0.04 2.49 0.2
41 INT178086 Binding of EDNRA and PTK2 1 0.07 0.82 0.2
42 INT60778 Edn1 Positive_regulation of EDNRA 1 0.00 0 0.18
43 INT334769 Ednra Positive_regulation of Car2 1 0.02 0.49 0.18
44 INT278828 Positive_regulation of Binding of EDN1 and EDNRA 1 0.06 0.51 0.15
45 INT115205 Positive_regulation of Ednra Positive_regulation of Localization of Avp 1 0.36 0 0.14
46 INT334770 Ednra Positive_regulation of Pla2g4a 1 0.00 0.24 0.14
47 INT334765 Ednra Positive_regulation of Positive_regulation of Car2 1 0.02 0.24 0.14
48 INT219920 EDNRA Positive_regulation of Trpv1 1 0.14 0 0.13
49 INT334759 Ednra Regulation of Gabrg1 1 0.01 0 0.13
50 INT334761 Binding of Ednra and Gopc 1 0.03 0 0.11
51 INT293627 GHRL Positive_regulation of EDNRA 1 0.00 0.96 0.1
52 INT139476 Edn1 Positive_regulation of Ednra 1 0.00 1.07 0.1
53 INT287887 WNT1 Positive_regulation of Localization of BMP4 1 0.04 1.13 0.1
54 INT284141 Binding of EDNRA and PAH 1 0.05 0.1 0.09
55 INT178089 Binding of EDNRA and Positive_regulation of PTK2 1 0.09 0.74 0.09
56 INT214752 EDNRA Positive_regulation of PLCB1 1 0.02 0 0.08
57 INT88752 Map3k7 Negative_regulation of Ednra 1 0.05 0 0.08
58 INT115204 Ednra Regulation of Localization of Avp 1 0.55 0 0.08
59 INT192908 Edn1 Positive_regulation of Ednra 1 0.21 0.35 0.07
60 INT337297 PTAFR Positive_regulation of EDNRA 1 0.04 1.2 0.06
61 INT178084 EDNRA Positive_regulation of Phosphorylation of GJA1 1 0.10 0.88 0.06
62 INT337303 Positive_regulation of PTAFR Positive_regulation of EDNRA 1 0.04 1.21 0.06
63 INT339778 Binding of EDNRA and PTH 1 0.12 0.35 0.05
64 INT210261 Bmp4 Regulation of Gene_expression of Tff3 1 0.64 0 0.05
65 INT274095 Binding of EDNRA and OPA1 1 0.12 0.65 0.04
66 INT107859 PRSS1 Positive_regulation of EDNRA 1 0.03 0.69 0.04
67 INT322891 Sox9 Regulation of Transcription of Col2a1 1 0.10 0.12 0.04
68 INT306560 BMP4 Positive_regulation of MAPK1 1 0.09 0.09 0.03
69 INT184208 IL1B Negative_regulation of SOX9 1 0.32 0 0.03
70 INT239229 Regulation of Binding of Edn1 and Ednra 1 0.01 0.37 0.03
71 INT210260 Sox9 Negative_regulation of Cdx2 1 0.20 0 0.03
72 INT115611 Binding of EDNRA and ERBB2 1 0.08 0.78 0
73 INT186603 Binding of ERBB2 and Ednra 1 0.02 0.53 0
74 INT320029 Gene_expression of SOX9 Positive_regulation of Gene_expression of COL7A1 1 0.03 0 0
75 INT334771 Binding of Ednra and Gfap 1 0.03 0 0
76 INT245726 SOX9 Regulation of SGCG 1 0.00 0.29 0
77 INT333879 Shc1 Positive_regulation of SOX9 1 0.01 0 0
78 INT225570 Ncoa6 Regulation of Sox9 1 0.16 0.72 0
79 INT196023 Bmp2 Negative_regulation of Gene_expression of Bmp4 1 0.09 0.07 0
80 INT196021 Bmp2 Positive_regulation of Gene_expression of Bmp4 1 0.09 0.08 0
81 INT156367 Ednra Positive_regulation of Gene_expression of Il10 1 0.01 0 0
82 INT196022 Bmp7 Regulation of Bmp4 1 0.06 0.06 0
83 INT245735 SOX9 Regulation of COL5A2 1 0.07 0.29 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of kidney development. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of kidney development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT23937 Gene_expression of EDNRA 103 0.65 55.63 24.67
2 INT6728 Gene_expression of Ednra 43 0.65 13.41 17.38
3 INT70905 Positive_regulation of EDNRA 49 0.67 24.33 11.79
4 INT6727 Positive_regulation of Ednra 27 0.64 18.75 8.71
5 INT30382 Negative_regulation of Ednra 21 0.42 12.06 8.19
6 INT77804 Regulation of Ednra 9 0.39 2.71 7.94
7 INT54978 Binding of EDNRA 36 0.41 14.97 7.86
8 INT67170 Gene_expression of Ednra 22 0.65 9.35 7.57
9 INT167049 Binding of Ednra 3 0.07 3.47 6.84
10 INT70907 Negative_regulation of EDNRA 30 0.36 19.68 5.49
11 INT60776 Regulation of EDNRA 20 0.51 16.62 5.36
12 INT92858 Negative_regulation of Ednra 6 0.57 1.25 4.81
13 INT246315 Localization of Ednra 22 0.15 2.73 4.64
14 INT21953 Binding of Ednra 12 0.33 4.72 4.56
15 INT115203 Negative_regulation of Positive_regulation of Ednra 5 0.33 1.27 3.32
16 INT49971 Regulation of Ednra 10 0.35 2.4 3.06
17 INT93058 Positive_regulation of Gene_expression of Ednra 8 0.28 4.11 2.88
18 INT76836 Positive_regulation of Ednra 6 0.55 2.65 2.72
19 INT156677 Regulation of Gene_expression of Ednra 4 0.15 0.25 2.05
20 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
21 INT72021 Localization of Ednra 7 0.58 3.13 1.53
22 INT23938 Positive_regulation of Gene_expression of EDNRA 8 0.45 9.82 1.47
23 INT129488 Regulation of Gene_expression of EDNRA 5 0.51 3.39 1.44
24 INT134663 Gene_expression of SOX9 40 0.75 9.07 1.2
25 INT72024 Localization of EDNRA 11 0.57 8.22 0.96
26 INT76835 Negative_regulation of Gene_expression of Ednra 2 0.10 0.89 0.96
27 INT166715 Gene_expression of Sox9 16 0.65 6.39 0.92
28 INT178133 Negative_regulation of Positive_regulation of EDNRA 2 0.35 2.18 0.88
29 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
30 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
31 INT145306 Gene_expression of Sox9 5 0.54 2.47 0.8
32 INT186579 Positive_regulation of Gene_expression of Ednra 5 0.07 0.89 0.76
33 INT313697 Phosphorylation of Ednra 1 0.18 0 0.7
34 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63
35 INT184222 Negative_regulation of SOX9 7 0.41 2.68 0.58
36 INT157103 Transcription of SOX9 6 0.59 1.2 0.58
37 INT157104 Positive_regulation of SOX9 6 0.66 1.66 0.52
38 INT186686 Regulation of Positive_regulation of EDNRA 5 0.22 2.35 0.51
39 INT157105 Positive_regulation of Transcription of SOX9 4 0.58 0.88 0.51
40 INT126442 Negative_regulation of Gene_expression of Ednra 3 0.33 1.94 0.51
41 INT115202 Positive_regulation of Positive_regulation of Ednra 2 0.39 2.88 0.49
42 INT120405 Phosphorylation of EDNRA 1 0.61 0.38 0.48
43 INT145304 Regulation of Gene_expression of Sox9 1 0.43 1.04 0.46
44 INT142124 Binding of Bmp4 1 0.35 0.46 0.45
45 INT324888 Transcription of Ednra 2 0.13 0.66 0.43
46 INT180688 Transcription of Bmp4 3 0.58 0.35 0.41
47 INT180702 Positive_regulation of Transcription of Bmp4 3 0.42 0.35 0.41
48 INT158057 Positive_regulation of Positive_regulation of EDNRA 2 0.15 0 0.41
49 INT72022 Positive_regulation of Localization of Ednra 2 0.32 0.07 0.3
50 INT350970 Negative_regulation of Binding of EDNRA 1 0.41 0.86 0.29
51 INT159213 Gene_expression of BMP4 8 0.74 2.1 0.28
52 INT159212 Positive_regulation of Gene_expression of BMP4 2 0.66 0.91 0.28
53 INT334747 Regulation of Binding of Ednra 1 0.06 0.05 0.28
54 INT185009 Negative_regulation of BMP4 2 0.56 1.04 0.25
55 INT145303 Regulation of Sox9 2 0.28 0.71 0.22
56 INT245763 Regulation of SOX9 4 0.43 1.68 0.21
57 INT142121 Positive_regulation of Gene_expression of Bmp4 3 0.47 7 0.21
58 INT334746 Positive_regulation of Localization of Ednra 1 0.07 0 0.2
59 INT134662 Positive_regulation of Gene_expression of SOX9 9 0.48 1.69 0.19
60 INT324881 Regulation of Transcription of Ednra 1 0.08 0.66 0.19
61 INT72023 Positive_regulation of Localization of EDNRA 1 0.02 0.07 0.18
62 INT72025 Negative_regulation of Localization of EDNRA 1 0.01 0.07 0.18
63 INT72020 Negative_regulation of Localization of Ednra 1 0.24 0.07 0.18
64 INT120085 Negative_regulation of Gene_expression of Bmp4 5 0.55 0.61 0.17
65 INT173335 Negative_regulation of Gene_expression of EDNRA 2 0.19 0.71 0.17
66 INT70908 Transcription of EDNRA 1 0.08 0.33 0.12
67 INT211949 Negative_regulation of Sox9 1 0.31 0.83 0.12
68 INT70906 Negative_regulation of Transcription of EDNRA 1 0.05 0.33 0.12
69 INT287912 Localization of BMP4 1 0.18 1.13 0.1
70 INT184220 Negative_regulation of Gene_expression of SOX9 4 0.36 0.58 0.09
71 INT196033 Negative_regulation of Gene_expression of Bmp4 3 0.21 0.45 0.09
72 INT211948 Regulation of Gene_expression of Sox9 2 0.33 0.94 0.08
73 INT334742 Negative_regulation of Transcription of Ednra 1 0.06 0 0.08
74 INT334749 Positive_regulation of Transcription of Ednra 1 0.07 0 0.08
75 INT210243 Negative_regulation of Bmp4 1 0.55 0.55 0.07
76 INT210242 Positive_regulation of Sox9 3 0.43 0.35 0.06
77 INT211939 Regulation of Sox9 1 0.33 0.35 0.06
78 INT283233 Regulation of Regulation of EDNRA 1 0.04 2.22 0.05
79 INT196030 Positive_regulation of Bmp4 6 0.62 2.55 0.04
80 INT210238 Positive_regulation of Negative_regulation of Bmp4 1 0.47 0 0.04
81 INT246353 Protein_catabolism of EDNRA 1 0.01 0.48 0.04
82 INT253182 Positive_regulation of Positive_regulation of Bmp4 1 0.45 0.58 0.04
83 INT225365 Binding of Sox9 2 0.28 0.48 0.03
84 INT145302 Positive_regulation of Sox9 2 0.48 1.42 0.03
85 INT334738 Negative_regulation of Positive_regulation of Ednra 1 0.06 0 0.03
86 INT334748 Positive_regulation of Positive_regulation of Ednra 1 0.07 0 0.03
87 INT196034 Positive_regulation of Gene_expression of Bmp4 4 0.45 0.63 0
88 INT260779 Negative_regulation of Bmp4 4 0.23 0.94 0
89 INT162339 Regulation of Gene_expression of SOX9 4 0.32 0.42 0
90 INT245757 Localization of SOX9 4 0.62 0.8 0
91 INT211945 Negative_regulation of Gene_expression of Sox9 3 0.44 0.63 0
92 INT196027 Binding of Bmp4 2 0.13 0.97 0
93 INT142119 Regulation of Bmp4 2 0.58 0.29 0
94 INT322883 Regulation of Transcription of Sox9 1 0.43 0.18 0
95 INT339667 Localization of Bmp4 1 0.38 0.27 0
96 INT211943 Transcription of Sox9 1 0.50 0.3 0
97 INT323815 Negative_regulation of Transcription of SOX9 1 0.41 0.18 0
98 INT246319 Regulation of Gene_expression of Ednra 1 0.05 0 0
99 INT322886 Transcription of Sox9 1 0.50 0.25 0
100 INT145307 Positive_regulation of Positive_regulation of Sox9 1 0.48 0.07 0
101 INT245752 Positive_regulation of Binding of SOX9 1 0.41 0.48 0
102 INT334743 Negative_regulation of Binding of Ednra 1 0.06 0 0
103 INT186688 Regulation of Binding of EDNRA 1 0.03 0.36 0
104 INT245765 Binding of SOX9 1 0.31 0.87 0
105 INT312245 Positive_regulation of Localization of SOX9 1 0.10 0 0
106 INT334741 Regulation of Localization of Ednra 1 0.06 0 0
107 INT351554 Negative_regulation of Gene_expression of BMP4 1 0.26 0 0
108 INT186687 Negative_regulation of Regulation of EDNRA 1 0.03 0.28 0
109 INT352010 Protein_catabolism of Sox9 1 0.22 0.07 0
110 INT308349 Positive_regulation of Gene_expression of Sox9 1 0.40 0.69 0
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