GO:0090274

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Name positive regulation of somatostatin secretion
Categary Process
Go Slim No
Go Link GO:0090274
Unique Molecular Interactions 71
Total Molecular Interactions 107
Total Single Events 526
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of somatostatin secretion. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of somatostatin secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
2 INT142207 Adcyap1 Positive_regulation of Localization of Gh 1 0.07 0 1.3
3 INT74467 Adcyap1 Positive_regulation of Localization of Gh1 1 0.37 0 1.25
4 INT133496 Binding of Oprm1 and Cckbr 1 0.15 0 1.19
5 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
6 INT133497 Binding of Oprm1 and Cckbr 1 0.03 0 1.1
7 INT48260 Binding of Adcyap1 and Calca 1 0.35 0 1.04
8 INT210015 Binding of Adcyap1 and Crh 1 0.47 0.88 1
9 INT11392 Cck Positive_regulation of Cckbr 1 0.52 0 0.96
10 INT161769 Cck Regulation of Cckar 1 0.27 0.53 0.92
11 INT120825 Adcyap1 Positive_regulation of Localization of Nos1 1 0.26 0.62 0.85
12 INT142208 Adcyap1 Positive_regulation of Transcription of Gh 1 0.05 0 0.77
13 INT142210 Adcyap1 Positive_regulation of Gh 1 0.05 0 0.77
14 INT74468 Adcyap1 Positive_regulation of Localization of Gnrhr 1 0.27 0 0.67
15 INT84213 Cck Regulation of Cckbr 1 0.41 0 0.67
16 INT142209 Adcyap1 Positive_regulation of Gene_expression of Gh 1 0.05 0 0.63
17 INT59155 Binding of Adcyap1 and Vip 2 0.34 0.08 0.55
18 INT142206 Negative_regulation of Adcyap1 Positive_regulation of Gh 1 0.04 0 0.54
19 INT106662 Adcyap1 Regulation of Penk 1 0.00 0 0.49
20 INT106664 Adcyap1 Regulation of Gene_expression of Vip 1 0.00 0 0.49
21 INT106663 Adcyap1 Regulation of Vip 1 0.00 0 0.49
22 INT26009 Cck Negative_regulation of Positive_regulation of Cckbr 1 0.26 0 0.47
23 INT55261 Cck Regulation of Positive_regulation of Cckbr 1 0.18 0 0.45
24 INT55264 Pigt Regulation of Positive_regulation of Cckbr 1 0.03 0 0.44
25 INT190739 Adcyap1 Regulation of Gene_expression of Scn2a1 1 0.13 0 0.39
26 INT273045 Vip Regulation of Adcyap1 1 0.17 0.5 0.38
27 INT187230 Binding of Adcyap1 and Vipr1 1 0.11 0.92 0.38
28 INT187228 Binding of Adcyap1 and Vipr2 1 0.11 0.91 0.38
29 INT190751 Adcyap1 Positive_regulation of Vipr2 2 0.16 1.02 0.36
30 INT315385 Adcyap1 Positive_regulation of Phosphorylation of Bad 1 0.05 0.44 0.32
31 INT315387 Adcyap1 Positive_regulation of Phosphorylation of Gopc 1 0.03 0.44 0.32
32 INT168948 Binding of CCK and CCKAR 1 0.23 0 0.3
33 INT118239 Binding of CCKAR and CYP2B6 1 0.32 0.19 0.29
34 INT139125 Adcyap1 Regulation of Ier3 1 0.54 0.8 0.29
35 INT58898 Adcyap1 Regulation of Localization of Acot1 1 0.17 0 0.28
36 INT63654 VIP Positive_regulation of Adcyap1 1 0.27 0.15 0.27
37 INT74118 Adcyap1 Positive_regulation of Localization of Avp 1 0.33 0 0.26
38 INT106658 Adcyap1 Positive_regulation of Gene_expression of Npy 1 0.54 0.16 0.25
39 INT106660 Adcyap1 Positive_regulation of Gene_expression of Chga 1 0.54 0.16 0.25
40 INT190741 Adcyap1 Positive_regulation of Gria2 1 0.00 0 0.24
41 INT69073 Adcyap1 Regulation of Localization of Gnrh1 2 0.66 0 0.22
42 INT273046 Vip Negative_regulation of Gene_expression of Adcyap1 1 0.20 1.14 0.21
43 INT190745 Adcyap1 Regulation of Car2 1 0.08 0 0.21
44 INT315384 Adcyap1 Negative_regulation of Positive_regulation of Casp3 1 0.02 0.53 0.2
45 INT315386 Adcyap1 Positive_regulation of Bad 1 0.03 0.52 0.2
46 INT80049 Adcyap1 Positive_regulation of Positive_regulation of Slc4a4 1 0.19 0 0.2
47 INT273048 Adcyap1 Positive_regulation of Adcyap1r1 1 0.11 1.02 0.19
48 INT315396 Adcyap1 Regulation of IFNA1 1 0.02 0.14 0.17
49 INT190749 Adcyap1 Positive_regulation of Vipr1 1 0.11 0 0.17
50 INT190744 Adcyap1 Positive_regulation of Car2 1 0.10 0.08 0.16
51 INT74030 Adcyap1 Positive_regulation of Transcription of Penk 1 0.56 0.24 0.15
52 INT190747 Adcyap1 Regulation of Positive_regulation of Prkaca 1 0.05 0 0.14
53 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13
54 INT315388 Binding of Adcyap1r1 and Adcyap1 1 0.02 0.5 0.12
55 INT190743 Adcyap1 Regulation of Gene_expression of Car2 1 0.10 0.06 0.12
56 INT72729 Adcyap1 Positive_regulation of Localization of Slc4a4 1 0.23 0 0.12
57 INT93478 Adcyap1 Regulation of Vip 1 0.31 0 0.1
58 INT139250 CCKAR Positive_regulation of Localization of POMC 1 0.35 0.61 0.09
59 INT41574 POMC Regulation of CCKAR 1 0.00 0 0.09
60 INT315383 Adcyap1 Regulation of Stat1 1 0.10 0.07 0.09
61 INT171400 Binding of Adcyap1 and Prkcg 1 0.01 0.24 0.08
62 INT190742 Adcyap1 Regulation of Gria2 1 0.00 0 0.08
63 INT110952 Adcyap1 Regulation of Localization of LH 1 0.22 0 0.07
64 INT315399 Adcyap1 Positive_regulation of Binding of IFNA1 1 0.02 0 0.06
65 INT190750 Adcyap1 Regulation of Positive_regulation of Adcyap1r1 1 0.11 0 0.06
66 INT206675 Adcyap1 Positive_regulation of Gene_expression of Per1 1 0.05 0 0.05
67 INT171401 Binding of Adcyap1 and Npr1 1 0.02 0.23 0.04
68 INT190738 Adcyap1 Positive_regulation of Gene_expression of Gnb2l1 1 0.08 0 0.03
69 INT190748 Adcyap1 Regulation of Gene_expression of Gopc 1 0.05 0 0.03
70 INT191614 Adcyap1 Positive_regulation of Rtcd1 1 0.01 0.93 0
71 INT74023 Adcyap1 Regulation of Transcription of Penk 1 0.32 0.2 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of somatostatin secretion. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of somatostatin secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT54077 Gene_expression of Adcyap1 62 0.78 23.17 16.75
2 INT58896 Localization of Adcyap1 35 0.81 4.57 14.77
3 INT48259 Positive_regulation of Adcyap1 33 0.67 10.94 14.39
4 INT65965 Gene_expression of Adcyap1 52 0.78 22.53 13.14
5 INT106199 Positive_regulation of Adcyap1 32 0.68 13.68 9.14
6 INT52116 Regulation of Adcyap1 20 0.53 6.1 8.14
7 INT6856 Gene_expression of Cckbr 10 0.77 1.8 7.69
8 INT51062 Negative_regulation of Cckbr 7 0.59 1.98 7.68
9 INT65964 Regulation of Adcyap1 13 0.45 10.1 7.54
10 INT43224 Negative_regulation of Adcyap1 17 0.54 3.69 6.19
11 INT23725 Gene_expression of CCKAR 14 0.55 0.14 5.3
12 INT26008 Positive_regulation of Cckbr 5 0.65 1.47 5.01
13 INT66048 Positive_regulation of Gene_expression of Adcyap1 5 0.49 8.21 4.52
14 INT54776 Binding of Cckbr 5 0.42 0 4.45
15 INT106548 Localization of Adcyap1 14 0.80 5.05 4.33
16 INT138209 Positive_regulation of Localization of Adcyap1 2 0.41 2.07 4.08
17 INT115877 Negative_regulation of Adcyap1 14 0.59 5.31 3.74
18 INT59154 Binding of Adcyap1 12 0.48 4.16 3.71
19 INT52170 Regulation of Cckbr 5 0.58 1.34 3.69
20 INT23728 Negative_regulation of CCKAR 6 0.42 0.48 3.53
21 INT58897 Regulation of Localization of Adcyap1 4 0.45 1.82 3.48
22 INT120823 Positive_regulation of Gene_expression of Adcyap1 10 0.68 6.71 3.22
23 INT85947 Regulation of Cckar 2 0.36 2.4 2.86
24 INT23534 Regulation of CCKAR 8 0.32 0.17 2.56
25 INT40505 Positive_regulation of CCKAR 3 0.40 0 2.42
26 INT54076 Transcription of Adcyap1 4 0.67 1.65 1.98
27 INT77300 Negative_regulation of Positive_regulation of Adcyap1 3 0.35 0 1.88
28 INT66047 Regulation of Gene_expression of Adcyap1 2 0.58 3.36 1.84
29 INT30373 Localization of CCKAR 5 0.68 0.17 1.79
30 INT54775 Binding of Cckar 1 0.34 0 1.43
31 INT59153 Positive_regulation of Binding of Adcyap1 3 0.43 0.56 1.37
32 INT168954 Binding of CCKAR 1 0.28 0 1.36
33 INT23727 Positive_regulation of Gene_expression of CCKAR 4 0.31 0 1.34
34 INT141010 Positive_regulation of Gene_expression of Cckbr 1 0.44 0.67 1.34
35 INT141009 Transcription of Cckbr 1 0.47 0.67 1.33
36 INT106549 Binding of Adcyap1 3 0.35 1.83 1.08
37 INT85610 Positive_regulation of Positive_regulation of Cckbr 1 0.14 0.25 1.06
38 INT43221 Negative_regulation of Negative_regulation of Adcyap1 1 0.18 0 0.85
39 INT23726 Positive_regulation of Negative_regulation of CCKAR 1 0.08 0 0.82
40 INT23953 Gene_expression of Cckar 3 0.65 0.2 0.74
41 INT210014 Regulation of Binding of Adcyap1 1 0.38 0.25 0.73
42 INT210012 Regulation of Transcription of Adcyap1 1 0.44 0.48 0.7
43 INT210011 Negative_regulation of Gene_expression of Adcyap1 1 0.36 1.22 0.69
44 INT168965 Negative_regulation of Binding of CCKAR 1 0.22 0 0.63
45 INT168966 Positive_regulation of Localization of CCKAR 1 0.29 0 0.62
46 INT25006 Negative_regulation of Gene_expression of CCKAR 1 0.30 0 0.62
47 INT137580 Negative_regulation of Gene_expression of Adcyap1 3 0.43 0.15 0.57
48 INT62101 Protein_catabolism of CCKAR 1 0.01 0 0.54
49 INT39113 Negative_regulation of Cckar 2 0.41 0.28 0.5
50 INT68358 Regulation of Positive_regulation of Adcyap1 1 0.44 0 0.5
51 INT26007 Negative_regulation of Positive_regulation of Cckbr 1 0.33 0 0.47
52 INT203480 Negative_regulation of Transcription of Adcyap1 1 0.41 0.81 0.47
53 INT51063 Regulation of Negative_regulation of Cckbr 1 0.25 0 0.47
54 INT203479 Transcription of Adcyap1 1 0.67 0.81 0.47
55 INT115876 Regulation of Gene_expression of Adcyap1 1 0.38 0.47 0.44
56 INT190727 Negative_regulation of Positive_regulation of Adcyap1 1 0.27 0 0.25
57 INT69072 Positive_regulation of Negative_regulation of Adcyap1 1 0.50 0 0.25
58 INT30371 Regulation of Localization of CCKAR 1 0.18 0.17 0.22
59 INT54751 Localization of Cckbr 1 0.71 0 0.21
60 INT10042 Protein_catabolism of Cckar 1 0.08 0 0.18
61 INT76880 Localization of Cckar 2 0.07 0.08 0.17
62 INT284590 Regulation of Localization of Adcyap1 1 0.07 0 0.17
63 INT190732 Regulation of Positive_regulation of Adcyap1 1 0.33 0 0.13
64 INT116635 Positive_regulation of Localization of Adcyap1 1 0.70 0 0.11
65 INT273033 Regulation of Binding of Adcyap1 1 0.31 0.63 0.1
66 INT315377 Negative_regulation of Binding of Adcyap1 1 0.18 0.07 0.09
67 INT131055 Positive_regulation of Cckar 1 0.36 0 0.09
68 INT87511 Regulation of Regulation of Adcyap1 1 0.23 0.57 0.08
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