GO:0090303

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Name positive regulation of wound healing
Categary Process
Go Slim No
Go Link GO:0090303
Unique Molecular Interactions 97
Total Molecular Interactions 133
Total Single Events 1209
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of wound healing. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of wound healing. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT123451 Binding of YY1 and Adra2a 1 0.37 0 2.98
2 INT25708 Oprl1 Positive_regulation of Adra2a 1 0.25 0.15 2.63
3 INT147659 Prkce Positive_regulation of TRPV1 1 0.04 1.42 2.43
4 INT113550 Binding of FN1 and VTN 6 0.30 5.24 1.91
5 INT135582 Prok2 Positive_regulation of Localization of Prkce 1 0.06 1.02 1.87
6 INT24817 Binding of POMC and VTN 8 0.42 0.39 1.71
7 INT18786 Binding of Adra2a and Nisch 2 0.19 0 1.7
8 INT150835 Gper Positive_regulation of Localization of Prkce 1 0.15 0.62 1.18
9 INT147660 Positive_regulation of Prkce Positive_regulation of TRPV1 1 0.04 0.69 1.12
10 INT96905 Plxna3 Regulation of Regulation of Prkce 1 0.18 0.71 1.07
11 INT41175 Adra2a Regulation of Th 1 0.59 0 1.04
12 INT144661 Dnm1 Negative_regulation of Binding of Hbegf 1 0.24 0 1.01
13 INT63543 Binding of Adra2a and Serpini1 1 0.13 0 1
14 INT127263 Adra2a Regulation of Gene_expression of Jun 1 0.07 1.1 0.95
15 INT109842 Prkce Positive_regulation of Localization of Trpv1 1 0.13 1.31 0.91
16 INT28921 Adra2a Positive_regulation of Localization of Prl 1 0.24 0 0.9
17 INT43796 Binding of CDS1 and Adra2a 1 0.06 0 0.86
18 INT63544 Adra2a Regulation of Nisch 1 0.18 0 0.79
19 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
20 INT113549 Binding of VTN and alphavbeta3 integrin receptor 1 0.09 2.05 0.76
21 INT108611 Adra2a Regulation of Gene_expression of Nos1 1 0.10 0 0.75
22 INT84283 Binding of Adra2a and Htr1f 1 0.16 0.15 0.74
23 INT20688 Adra2a Regulation of Localization of Gh1 1 0.26 0.37 0.7
24 INT81968 Binding of PLEK and Adra2a 1 0.07 0.1 0.7
25 INT148454 Gene_expression of Inhbe Positive_regulation of Prkce 1 0.08 0.67 0.69
26 INT154766 Nox1 Positive_regulation of Localization of Prkce 1 0.47 0.45 0.66
27 INT132152 Adra2a Regulation of Localization of Abat 1 0.03 0 0.66
28 INT153921 Positive_regulation of Adra2a Regulation of Ednrb 1 0.01 0 0.66
29 INT112513 Binding of Prkaca and Prkce 1 0.04 0.4 0.64
30 INT112516 Binding of Prkce and Trib3 1 0.01 0.4 0.64
31 INT152766 TAT Positive_regulation of Positive_regulation of MYLK 1 0.44 0.67 0.61
32 INT17187 Binding of Adra2a and Fabp6 1 0.16 0.69 0.61
33 INT17186 Positive_regulation of Binding of Adra2a and Fabp6 1 0.21 0.69 0.61
34 INT152765 TAT Regulation of Positive_regulation of MYLK 1 0.40 0.66 0.6
35 INT41250 Binding of Adra2a and Eef1a1 1 0.06 0.4 0.56
36 INT227911 Binding of VTN and MMRN1 1 0.01 1.16 0.56
37 INT144129 Prkce Positive_regulation of Phosphorylation of Gja1 1 0.42 0.48 0.55
38 INT144128 Binding of Gja1 and Prkce 1 0.40 0.5 0.52
39 INT140356 Prkca Regulation of Phosphorylation of Prkce 1 0.18 0.44 0.52
40 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
41 INT7851 Man2a2 Positive_regulation of Adra2a 1 0.13 0 0.49
42 INT146113 Binding of Adra2a and Lrp1 1 0.01 1.07 0.48
43 INT26448 Adra2a Regulation of Positive_regulation of Npy 1 0.06 0 0.46
44 INT106001 Binding of PLAUR and VTN 2 0.23 1.5 0.45
45 INT86380 Adra2a Regulation of Gene_expression of Tnf 1 0.15 0.79 0.44
46 INT56576 Adra2a Positive_regulation of Localization of Gnrh1 1 0.44 0 0.43
47 INT55395 Binding of Htr1a and Adra2a 1 0.42 0 0.43
48 INT34987 Adra2a Positive_regulation of Localization of Gnrhr 1 0.43 0 0.4
49 INT346148 Binding of ADM and VTN 1 0.15 0.93 0.39
50 INT134167 Binding of ADRA2A and APLP1 1 0.09 0.64 0.39
51 INT346142 Positive_regulation of Binding of ADM and VTN 1 0.20 0.93 0.39
52 INT113551 Binding of ITGA3 and VTN 1 0.02 1.03 0.38
53 INT70656 Adra2a Regulation of Gene_expression of Npy 1 0.23 0 0.38
54 INT113555 Negative_regulation of Binding of FN1 and VTN 1 0.23 0.87 0.37
55 INT113559 Binding of PLAU and VTN 1 0.28 0.82 0.37
56 INT113554 Negative_regulation of Binding of PLAU and VTN 1 0.32 0.87 0.37
57 INT113547 Negative_regulation of Binding of PLAUR and VTN 1 0.26 0.87 0.37
58 INT67030 Negative_regulation of Adra2a Negative_regulation of Etf1 1 0.00 0.64 0.33
59 INT67028 Adra2a Negative_regulation of Nts 1 0.06 0.64 0.33
60 INT67029 Adra2a Negative_regulation of Etf1 1 0.00 0.64 0.33
61 INT31182 Adra2a Regulation of Localization of Gh 1 0.01 0.35 0.32
62 INT95061 Binding of Adra2a and ADHD1 1 0.02 0.8 0.27
63 INT42635 Adra2a Positive_regulation of epi 1 0.00 0 0.26
64 INT55641 Binding of CHRM1 and Adra2a 1 0.00 0 0.24
65 INT32735 ADRA2A Regulation of RTCA 1 0.07 0 0.22
66 INT291798 Binding of CALM1 and Positive_regulation of MYLK 1 0.09 0.33 0.19
67 INT291797 Binding of CA2 and Positive_regulation of MYLK 1 0.15 0.33 0.19
68 INT293712 Binding of Adra2a and Atl1 1 0.06 0.83 0.15
69 INT106009 Binding of VTN and Plaur 1 0.05 1.37 0.15
70 INT103425 Binding of Adra2a and Cyth2 1 0.00 0 0.14
71 INT109082 Adra2a Regulation of Nppa 1 0.21 0.56 0.14
72 INT134614 Prkce Regulation of Trpv1 1 0.30 0.15 0.13
73 INT117136 NPEPPS Positive_regulation of Hbegf 1 0.00 0 0.12
74 INT110107 Acot1 Positive_regulation of Localization of Prkce 1 0.11 0 0.12
75 INT164060 MYLK Positive_regulation of EFS 1 0.08 0.08 0.1
76 INT17394 Adra2a Positive_regulation of GNAI1 1 0.02 0.37 0.1
77 INT66171 Negative_regulation of Adra2a Negative_regulation of Positive_regulation of Pnmt 1 0.38 0 0.08
78 INT66166 Negative_regulation of Binding of Pnmt and Adra2a 1 0.38 0 0.07
79 INT66167 Negative_regulation of Pnmt Negative_regulation of Adra2a 1 0.38 0 0.07
80 INT66172 Binding of Pnmt and Adra2a 1 0.33 0 0.07
81 INT348715 Positive_regulation of Binding of Ca2 and Mylk 1 0.02 0.47 0.05
82 INT348716 Binding of Ca2 and Mylk 1 0.02 0.47 0.05
83 INT91832 CD81 Negative_regulation of Gene_expression of Hbegf 1 0.01 0.07 0
84 INT169448 Binding of Prkce and Trpv4 1 0.04 0.08 0
85 INT66168 Pde2a Negative_regulation of Adra2a 1 0.04 0 0
86 INT257547 HBEGF Positive_regulation of Phosphorylation of CDCP1 1 0.00 0.36 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of wound healing. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of wound healing. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7059 Regulation of Adra2a 89 0.62 18.24 48.43
2 INT7608 Positive_regulation of Adra2a 66 0.70 17.81 35.15
3 INT7779 Negative_regulation of Adra2a 47 0.58 9.45 28
4 INT7717 Positive_regulation of Adra2a 62 0.70 17.68 27.32
5 INT8248 Binding of Adra2a 43 0.48 6.72 22.17
6 INT3030 Gene_expression of Adra2a 37 0.68 5.58 19.76
7 INT14114 Binding of Adra2a 30 0.48 4.24 18.53
8 INT12875 Regulation of Adra2a 26 0.45 7.51 17.35
9 INT5674 Gene_expression of Adra2a 34 0.77 6.14 15.13
10 INT88650 Negative_regulation of Prkce 13 0.57 11.93 11.16
11 INT91948 Positive_regulation of Prkce 16 0.64 11.36 10.32
12 INT12455 Negative_regulation of Adra2a 30 0.54 5.63 10.14
13 INT72148 Positive_regulation of Prkce 17 0.68 5.06 9.44
14 INT6576 Localization of Adra2a 11 0.71 1.49 7.18
15 INT110104 Localization of Prkce 17 0.79 3.75 6.92
16 INT21138 Binding of ADRA2A 16 0.48 5.57 6.8
17 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68
18 INT101497 Phosphorylation of Prkce 9 0.81 2.55 5.59
19 INT91946 Regulation of Prkce 6 0.44 4.13 5.46
20 INT109838 Phosphorylation of Prkce 6 0.67 5.26 4.95
21 INT13650 Positive_regulation of Gene_expression of Adra2a 6 0.50 0.69 4.94
22 INT7716 Positive_regulation of Positive_regulation of Adra2a 9 0.68 0.8 4.69
23 INT60758 Gene_expression of Prkce 8 0.20 4.12 4.59
24 INT71716 Binding of Hbegf 21 0.28 6.54 4.51
25 INT109840 Localization of Prkce 5 0.74 3.01 3.45
26 INT71717 Negative_regulation of Hbegf 15 0.39 3.63 3.18
27 INT110100 Negative_regulation of Prkce 5 0.57 0.68 3.16
28 INT77333 Binding of Hbegf 5 0.32 2.39 3.07
29 INT17389 Negative_regulation of Positive_regulation of Adra2a 6 0.58 0.99 3.06
30 INT24821 Binding of VTN 14 0.47 5.83 3
31 INT7931 Positive_regulation of Protein_catabolism of Adra2a 1 0.70 0 2.9
32 INT31923 Positive_regulation of Positive_regulation of Adra2a 7 0.44 1.88 2.89
33 INT31451 Negative_regulation of Gene_expression of Adra2a 4 0.43 1.03 2.72
34 INT128184 Positive_regulation of Positive_regulation of Prkce 4 0.41 1.3 2.64
35 INT91825 Binding of HBEGF 4 0.31 2.39 2.52
36 INT43212 Regulation of Gene_expression of Adra2a 4 0.45 0.24 2.48
37 INT12456 Negative_regulation of Positive_regulation of Adra2a 4 0.37 1.35 2.42
38 INT53587 Positive_regulation of Binding of Adra2a 1 0.12 0 2.26
39 INT128185 Gene_expression of Prkce 4 0.69 1.39 2.23
40 INT34196 Regulation of Binding of Adra2a 2 0.45 0 2.12
41 INT136941 Positive_regulation of Localization of Prkce 3 0.43 1.42 2.06
42 INT31262 Positive_regulation of Binding of Adra2a 4 0.10 1.02 2.04
43 INT124052 Binding of Prkce 2 0.06 2.52 2.03
44 INT64709 Gene_expression of VTN 11 0.67 11.01 1.97
45 INT23426 Regulation of ADRA2A 8 0.48 1.81 1.88
46 INT87454 Gene_expression of Hbegf 11 0.66 2.1 1.67
47 INT91739 Positive_regulation of MYLK 9 0.54 2.89 1.58
48 INT43327 Positive_regulation of ADRA2A 3 0.46 1.54 1.53
49 INT7780 Positive_regulation of Negative_regulation of Adra2a 2 0.50 0.09 1.48
50 INT129099 Negative_regulation of Hbegf 4 0.36 1.2 1.46
51 INT7932 Protein_catabolism of Adra2a 1 1.00 0 1.44
52 INT53632 Regulation of Negative_regulation of Adra2a 1 0.23 0.08 1.41
53 INT29262 Negative_regulation of Binding of Adra2a 4 0.40 0.25 1.37
54 INT95815 Regulation of Positive_regulation of Adra2a 4 0.45 1.45 1.32
55 INT91947 Negative_regulation of Negative_regulation of Prkce 1 0.42 0.69 1.3
56 INT136991 Localization of HBEGF 5 0.59 3.62 1.28
57 INT7847 Positive_regulation of Localization of Adra2a 2 0.40 0.22 1.28
58 INT110099 Positive_regulation of Localization of Prkce 4 0.68 1.3 1.25
59 INT91949 Regulation of Positive_regulation of Prkce 1 0.44 0.72 1.24
60 INT24819 Positive_regulation of VTN 8 0.49 3.52 1.23
61 INT79489 Transcription of Adra2a 2 0.61 2.38 1.22
62 INT110106 Regulation of Prkce 4 0.44 0.4 1.2
63 INT110102 Negative_regulation of Localization of Prkce 3 0.49 0.17 1.13
64 INT117134 Localization of Hbegf 5 0.50 0.37 1.12
65 INT131238 Negative_regulation of Positive_regulation of Prkce 1 0.41 0.44 1.12
66 INT87452 Negative_regulation of Binding of Hbegf 4 0.32 1.94 1.11
67 INT12976 Negative_regulation of ADRA2A 4 0.50 0.16 1.01
68 INT78561 Gene_expression of Hbegf 4 0.56 2.65 0.97
69 INT135111 Regulation of Gene_expression of Prkce 1 0.51 0.15 0.96
70 INT135115 Regulation of Localization of Prkce 1 0.38 0.15 0.96
71 INT20687 Positive_regulation of Regulation of Adra2a 1 0.35 1.07 0.95
72 INT87453 Regulation of Hbegf 3 0.20 1.05 0.94
73 INT86458 Positive_regulation of Hbegf 4 0.41 2 0.93
74 INT18801 Negative_regulation of Negative_regulation of Adra2a 2 0.43 0 0.91
75 INT87455 Positive_regulation of Gene_expression of Hbegf 5 0.59 1.01 0.86
76 INT136944 Positive_regulation of Positive_regulation of Prkce 2 0.46 0.8 0.85
77 INT14770 Localization of Adra2a 2 0.60 0.1 0.78
78 INT18836 Localization of ADRA2A 2 0.38 0.33 0.76
79 INT11102 Negative_regulation of Regulation of Adra2a 2 0.42 1.5 0.71
80 INT109839 Positive_regulation of Phosphorylation of Prkce 1 0.18 1.27 0.71
81 INT154761 Positive_regulation of Gene_expression of Prkce 1 0.44 0.5 0.7
82 INT154762 Negative_regulation of Phosphorylation of Prkce 1 0.38 0.48 0.69
83 INT7609 Regulation of Positive_regulation of Adra2a 3 0.32 0.59 0.66
84 INT346193 Positive_regulation of Gene_expression of VTN 1 0.25 1.54 0.63
85 INT91831 Gene_expression of HBEGF 2 0.63 1.93 0.6
86 INT117133 Positive_regulation of Localization of Hbegf 3 0.43 0.38 0.59
87 INT152068 Regulation of Gene_expression of Prkce 1 0.05 0.74 0.56
88 INT82128 Negative_regulation of Transcription of Adra2a 1 0.18 1.32 0.55
89 INT59394 Regulation of Regulation of Adra2a 1 0.17 0 0.55
90 INT31363 Positive_regulation of Regulation of Adra2a 1 0.04 0 0.55
91 INT30428 Positive_regulation of Binding of ADRA2A 1 0.34 0.59 0.53
92 INT144660 Negative_regulation of Negative_regulation of Hbegf 1 0.21 0 0.53
93 INT91828 Negative_regulation of Gene_expression of HBEGF 1 0.47 0.45 0.52
94 INT77904 Negative_regulation of Gene_expression of Adra2a 2 0.43 0.87 0.5
95 INT91827 Negative_regulation of Binding of HBEGF 1 0.34 0.44 0.5
96 INT91826 Negative_regulation of HBEGF 1 0.47 0.44 0.5
97 INT41146 Negative_regulation of Localization of Adra2a 1 0.37 0.1 0.49
98 INT136942 Negative_regulation of Positive_regulation of Prkce 1 0.39 0.66 0.48
99 INT29102 Transcription of ADRA2A 2 0.27 0.83 0.46
100 INT86459 Positive_regulation of Positive_regulation of Hbegf 1 0.13 0.1 0.46
101 INT33171 Positive_regulation of Negative_regulation of Adra2a 1 0.39 0 0.4
102 INT29100 Negative_regulation of Binding of ADRA2A 1 0.19 0.84 0.37
103 INT33569 Gene_expression of MYLK 6 0.25 2.56 0.34
104 INT111674 Phosphorylation of MYLK 3 0.81 0.35 0.33
105 INT209502 Positive_regulation of HBEGF 1 0.03 2.48 0.33
106 INT29101 Positive_regulation of Transcription of ADRA2A 1 0.19 0.76 0.32
107 INT193609 Protein_catabolism of HBEGF 4 0.30 2.77 0.3
108 INT8449 Positive_regulation of Phosphorylation of Mylk 1 0.05 0.16 0.3
109 INT8448 Phosphorylation of Mylk 1 0.07 0.16 0.3
110 INT13453 Regulation of Negative_regulation of Adra2a 2 0.27 0.49 0.28
111 INT24992 Regulation of Mylk 2 0.20 0.4 0.26
112 INT86463 Regulation of Gene_expression of Hbegf 1 0.05 0.59 0.26
113 INT134176 Gene_expression of ADRA2A 4 0.58 1.45 0.25
114 INT25928 Positive_regulation of Negative_regulation of ADRA2A 1 0.05 0 0.23
115 INT140351 Binding of Prkce 2 0.28 0.32 0.22
116 INT169685 Regulation of Positive_regulation of Prkce 1 0.61 0.36 0.22
117 INT24818 Positive_regulation of Binding of VTN 1 0.49 0 0.18
118 INT71718 Positive_regulation of Hbegf 4 0.59 0.63 0.16
119 INT164831 Negative_regulation of Mylk 1 0.49 0.07 0.15
120 INT129100 Negative_regulation of Positive_regulation of Hbegf 1 0.36 0.64 0.14
121 INT134177 Positive_regulation of Gene_expression of ADRA2A 1 0.10 0.26 0.12
122 INT134178 Positive_regulation of Regulation of ADRA2A 1 0.10 0.24 0.12
123 INT173322 Negative_regulation of Gene_expression of MYLK 1 0.14 0.14 0.09
124 INT64708 Negative_regulation of Gene_expression of VTN 1 0.37 0.44 0.09
125 INT326308 Regulation of Gene_expression of HBEGF 1 0.01 1.48 0.08
126 INT173327 Positive_regulation of Gene_expression of MYLK 1 0.22 0.24 0.07
127 INT348719 Positive_regulation of Mylk 1 0.20 0.4 0.05
128 INT348722 Positive_regulation of Positive_regulation of Mylk 1 0.13 0.42 0.05
129 INT269650 Positive_regulation of Phosphorylation of MYLK 1 0.24 0.08 0.04
130 INT210662 Transcription of Adra2a 1 0.01 0.09 0
131 INT201215 Negative_regulation of Binding of VTN 1 0.19 0.69 0
132 INT175261 Positive_regulation of Negative_regulation of VTN 1 0.02 0.77 0
133 INT279581 Regulation of VTN 1 0.01 0.18 0
134 INT311856 Positive_regulation of Positive_regulation of MYLK 1 0.01 0.18 0
135 INT169684 Positive_regulation of Phosphorylation of Prkce 1 0.49 0.05 0
136 INT91822 Negative_regulation of Gene_expression of Hbegf 1 0.35 0 0
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