GO:0090336

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Name positive regulation of brown fat cell differentiation
Categary Process
Go Slim No
Go Link GO:0090336
Unique Molecular Interactions 168
Total Molecular Interactions 191
Total Single Events 3705
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of brown fat cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of brown fat cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
2 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45
3 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45
4 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
5 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16
6 INT126401 ITIH4 Positive_regulation of Gene_expression of Ptgs2 1 0.00 1.05 1.04
7 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03
8 INT60213 Binding of Ptgs1 and Ptgs2 2 0.37 0.5 0.97
9 INT116559 Olr1627 Negative_regulation of Regulation of Ptgs2 1 0.01 1.52 0.86
10 INT149628 Il1b Regulation of Gene_expression of Ptgs2 1 0.30 0.84 0.84
11 INT62176 Binding of PTGS2 and Ptgs1 2 0.00 0.69 0.79
12 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78
13 INT158068 Positive_regulation of Pparg Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.28 0.76
14 INT65985 IL1B Positive_regulation of Gene_expression of PTGS2 3 0.23 2.62 0.71
15 INT71942 Negative_regulation of PTGS2 Negative_regulation of VN1R106P 1 0.00 0.07 0.62
16 INT101320 Negative_regulation of Ptgs1 Positive_regulation of Ptgs2 1 0.03 0.2 0.62
17 INT71944 PTGS2 Negative_regulation of VN1R106P 1 0.00 0.07 0.61
18 INT137247 Slc6a14 Negative_regulation of Ptgs2 2 0.19 1.38 0.58
19 INT137248 Slc6a14 Negative_regulation of Gene_expression of Ptgs2 1 0.19 1.32 0.58
20 INT125546 Arsa Negative_regulation of Gene_expression of PTGS2 1 0.00 0.53 0.58
21 INT87294 SERPINA3 Negative_regulation of PTGS2 1 0.25 0.6 0.58
22 INT254197 Mif Regulation of Ptgs2 1 0.02 1.08 0.55
23 INT71943 Regulation of ZNF697 Negative_regulation of PTGS2 1 0.01 0.07 0.54
24 INT129912 Skiv2l Negative_regulation of Gene_expression of PTGS2 1 0.00 0.87 0.54
25 INT161251 Ptgs2 Regulation of Mapk14 1 0.16 0.82 0.54
26 INT71945 ZNF697 Negative_regulation of PTGS2 1 0.01 0.07 0.53
27 INT69882 Ptger2 Positive_regulation of Gene_expression of Ptgs2 1 0.19 0.6 0.52
28 INT116541 Binding of Ptgs2 and ZNF398 1 0.00 0.68 0.52
29 INT150205 Tnrc6a Negative_regulation of PTGS2 1 0.00 0.42 0.49
30 INT135584 CSF2 Regulation of PTGS2 1 0.06 1.28 0.49
31 INT150788 ZNF398 Regulation of PTGS2 1 0.02 0.5 0.48
32 INT348402 LPA Positive_regulation of Gene_expression of Ptgs2 1 0.01 0.62 0.48
33 INT62164 Il1b Positive_regulation of PTGS2 1 0.00 0.49 0.47
34 INT62163 Il1b Positive_regulation of Positive_regulation of PTGS2 1 0.00 0.49 0.47
35 INT145434 Binding of HMOX1 and PTGS2 1 0.02 0.41 0.47
36 INT145436 Binding of HMOX2 and PTGS2 1 0.02 0.41 0.47
37 INT127662 Negative_regulation of PDE4A Negative_regulation of Gene_expression of PTGS2 1 0.15 0.75 0.47
38 INT106505 Binding of Ptgds and Ptgs2 1 0.01 0.93 0.39
39 INT200096 Negative_regulation of Il1a Negative_regulation of Gene_expression of Ptgs2 1 0.00 1.45 0.39
40 INT157171 Binding of PTGS2 and Pla2g1b 1 0.02 0.26 0.37
41 INT278766 HOXA9 Positive_regulation of Gene_expression of PTGS2 1 0.43 1.28 0.35
42 INT278749 NUP98 Positive_regulation of Gene_expression of PTGS2 1 0.46 1.28 0.35
43 INT89501 Il6 Positive_regulation of Ptgs2 1 0.01 1.07 0.35
44 INT89505 Nos2 Positive_regulation of Ptgs2 1 0.05 1.07 0.34
45 INT134303 Cpox Negative_regulation of PTGS2 1 0.00 0.77 0.34
46 INT89502 Positive_regulation of Nos2 Positive_regulation of Ptgs2 1 0.05 1.07 0.34
47 INT143567 Edn1 Regulation of Ptgs2 1 0.26 0.17 0.33
48 INT52700 Prkcg Positive_regulation of Ptgs2 1 0.12 0.3 0.32
49 INT108879 Negative_regulation of PTGS2 Positive_regulation of Protein_catabolism of Nfkbia 1 0.00 0.43 0.31
50 INT64859 Negative_regulation of PTGS1 Negative_regulation of PTGS2 1 0.07 0.05 0.31
51 INT116594 Negative_regulation of PTGS2 Negative_regulation of Gene_expression of IL6 1 0.22 0.45 0.31
52 INT139044 AKR1B1 Regulation of Gene_expression of PTGS2 1 0.09 0.37 0.3
53 INT156084 Binding of PTGS2 and AKR1C3 1 0.02 0.31 0.3
54 INT62207 Binding of PTGS1 and PTGS2 3 0.06 0.07 0.29
55 INT265467 HRAS Negative_regulation of Gene_expression of PTGS2 1 0.01 0.84 0.29
56 INT243214 Myst2 Negative_regulation of Gene_expression of Ptgs2 1 0.01 1.4 0.28
57 INT91751 Binding of PTGS2 and Hmox1 1 0.00 0.21 0.27
58 INT142447 PTGS2 Regulation of Gene_expression of PTGIS 1 0.30 0.24 0.27
59 INT107392 PTGS2 Positive_regulation of PTGS1 2 0.31 1.01 0.26
60 INT114069 Negative_regulation of Agtr2 Positive_regulation of Ptgs2 1 0.08 0.49 0.26
61 INT69120 MOCS1 Regulation of PTGS2 1 0.00 0.39 0.26
62 INT96402 Binding of PTGS2 and TBXAS1 1 0.02 0.32 0.26
63 INT64860 PTGS1 Negative_regulation of PTGS2 1 0.07 0 0.26
64 INT96401 Binding of PTGER1 and PTGS2 1 0.00 0.32 0.26
65 INT335126 Ptgs2 Positive_regulation of Gene_expression of PPARA 1 0.24 0.72 0.25
66 INT102625 IL6 Regulation of Gene_expression of PTGS2 1 0.11 0.29 0.24
67 INT136798 Spp1 Regulation of Gene_expression of PTGS2 1 0.08 0.65 0.24
68 INT126552 Agt Positive_regulation of Gene_expression of Ptgs2 1 0.32 0.92 0.24
69 INT166663 Mpzl2 Negative_regulation of Positive_regulation of Ptgs2 1 0.29 0.3 0.24
70 INT102617 PTAFR Regulation of Gene_expression of PTGS2 1 0.12 0.29 0.24
71 INT132382 Nos2 Positive_regulation of PTGS2 1 0.02 0.1 0.23
72 INT272143 PTAFR Positive_regulation of Gene_expression of PTGS2 1 0.12 1.59 0.23
73 INT126549 Agt Positive_regulation of Ptgs2 1 0.32 0.9 0.23
74 INT145014 Positive_regulation of GAST Positive_regulation of PTGS2 1 0.31 0.51 0.22
75 INT133164 Ptgs2 Regulation of Tnf 1 0.14 0.98 0.22
76 INT145012 GAST Positive_regulation of PTGS2 1 0.42 0.51 0.22
77 INT112134 Gast Positive_regulation of Gene_expression of Ptgs2 1 0.28 0.19 0.21
78 INT69318 ST3GAL4 Positive_regulation of Gene_expression of PTGS2 1 0.35 0.09 0.21
79 INT112136 Egf Positive_regulation of Gene_expression of Ptgs2 1 0.21 0.19 0.21
80 INT283747 Tbs1 Positive_regulation of Ptgs2 1 0.00 0 0.2
81 INT231639 Binding of PTGER2 and PTGS2 1 0.00 0.44 0.19
82 INT117517 PROC Positive_regulation of PTGS2 1 0.01 0.61 0.19
83 INT79651 PTGS2 Positive_regulation of Phosphorylation of NR3C1 1 0.07 0.1 0.19
84 INT206089 Negative_regulation of FOSB Negative_regulation of Gene_expression of PTGS2 1 0.00 0.97 0.19
85 INT139015 STAT1 Negative_regulation of Gene_expression of PTGS2 1 0.01 0.36 0.19
86 INT73332 IL1B Positive_regulation of Transcription of PTGS2 1 0.44 0.54 0.18
87 INT73331 PTAFR Positive_regulation of Transcription of PTGS2 1 0.13 0.54 0.18
88 INT119130 Binding of Nos2 and Ptgs2 1 0.33 0.07 0.17
89 INT354819 Binding of Cpox and Ptgs2 1 0.02 0.45 0.16
90 INT69317 PTGS2 Positive_regulation of Gene_expression of PTGS1 1 0.42 0.09 0.16
91 INT141753 Nfkb1 Regulation of Ptgs2 1 0.16 1.18 0.16
92 INT146745 UGCG Positive_regulation of Gene_expression of PTGS2 1 0.23 0.1 0.16
93 INT141754 Nfkb1 Regulation of Positive_regulation of Ptgs2 1 0.16 1.21 0.16
94 INT176621 PTGS2 Regulation of Gene_expression of PTGER2 1 0.00 0.09 0.15
95 INT87710 MYB Regulation of PTGS2 1 0.28 0.64 0.15
96 INT92342 Zfp697 Negative_regulation of Ptgs2 1 0.02 0.63 0.15
97 INT138321 PPA1 Positive_regulation of Gene_expression of PTGS2 1 0.02 0.09 0.14
98 INT141111 Sftpa1 Positive_regulation of Ptgs2 1 0.64 0.3 0.14
99 INT328851 Binding of PTGS2 and ZNF434 1 0.00 0.7 0.14
100 INT141112 Negative_regulation of Sftpa1 Positive_regulation of Ptgs2 1 0.39 0.31 0.14
101 INT81983 IL1A Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.27 0.13
102 INT306270 CCL4 Positive_regulation of Transcription of PTGS2 1 0.34 0.31 0.12
103 INT173129 PTGS2 Regulation of IER3 1 0.01 0.36 0.12
104 INT306262 NFKB1 Positive_regulation of Transcription of PTGS2 1 0.42 0.31 0.12
105 INT63521 Negative_regulation of Ptgs2 Negative_regulation of Gene_expression of Fos 1 0.66 0.1 0.12
106 INT117568 Dspp Negative_regulation of Ptgs2 1 0.11 0.13 0.12
107 INT147073 NFKB1 Regulation of PTGS2 1 0.37 0 0.11
108 INT133361 FABP6 Negative_regulation of PTGS2 1 0.01 0.07 0.11
109 INT52701 Slc3a1 Positive_regulation of Ptgs2 1 0.06 0.27 0.11
110 INT52702 Capza2 Positive_regulation of Ptgs2 1 0.00 0.27 0.11
111 INT294454 KLK4 Negative_regulation of PTGS2 1 0.01 0 0.1
112 INT87922 Gm7869 Negative_regulation of Ptgs2 1 0.01 0.56 0.1
113 INT327557 Pla2g4a Positive_regulation of Phosphorylation of Ptgs2 1 0.14 1.03 0.1
114 INT327559 Pla2g4a Positive_regulation of Gene_expression of Ptgs2 1 0.14 1 0.09
115 INT268325 Lep Positive_regulation of Ptgs2 1 0.09 0.39 0.08
116 INT140895 PTGS2 Positive_regulation of Gene_expression of VEGFA 1 0.27 0.07 0.07
117 INT98715 HGF Positive_regulation of Gene_expression of PTGS2 1 0.02 1.03 0.07
118 INT341882 Positive_regulation of Oxtr Positive_regulation of Positive_regulation of Ptgs2 1 0.02 0.11 0.05
119 INT17850 Binding of PTGS2 and Ptgs2 1 0.00 0.08 0.04
120 INT17851 Negative_regulation of Binding of PTGS2 and Ptgs2 1 0.00 0.08 0.04
121 INT331157 Ptgis Positive_regulation of Ptgs2 1 0.04 0.77 0.03
122 INT346838 ZNF434 Regulation of PTGS2 1 0.01 0.34 0
123 INT121545 Mif Negative_regulation of Regulation of Ptgs2 1 0.13 0.15 0
124 INT346836 MECP2 Regulation of PTGS2 1 0.00 0.34 0
125 INT352066 Binding of PTGS2 and PTGES2 1 0.04 0 0
126 INT149883 Agtr2 Positive_regulation of Gene_expression of Ptgs2 1 0.06 0.31 0
127 INT343163 ACSL4 Regulation of Gene_expression of PTGS2 1 0.08 0.5 0
128 INT352064 Binding of PTGS2 and HPGDS 1 0.20 0 0
129 INT165863 Binding of HSPG2 and PTGS2 1 0.01 0.19 0
130 INT352065 Binding of PTGDS and PTGS2 1 0.28 0 0
131 INT143293 Negative_regulation of Nfkb1 Negative_regulation of Gene_expression of PTGS2 1 0.00 0 0
132 INT166070 PTGS2 Regulation of VEGFA 1 0.29 0.06 0
133 INT350068 Positive_regulation of Hmox1 Negative_regulation of Gene_expression of Ptgs2 1 0.03 0.16 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of brown fat cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of brown fat cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85
2 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51
3 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08
4 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6
5 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73
6 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71
7 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39
8 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46
9 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02
10 INT50490 Regulation of PTGS2 80 0.48 39.51 25.85
11 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18
12 INT17848 Binding of PTGS2 70 0.46 32.1 20.6
13 INT52696 Positive_regulation of Ptgs2 48 0.70 27.65 14.44
14 INT59080 Negative_regulation of Gene_expression of PTGS2 55 0.58 22.92 12.39
15 INT53082 Positive_regulation of Gene_expression of Ptgs2 47 0.64 25.39 11.39
16 INT52689 Regulation of Ptgs2 27 0.60 12.76 10.6
17 INT53081 Negative_regulation of Gene_expression of Ptgs2 29 0.59 15.83 10.39
18 INT85535 Negative_regulation of Gene_expression of Ptgs2 27 0.51 16.04 10.01
19 INT69321 Regulation of Gene_expression of PTGS2 27 0.61 13.27 9.53
20 INT52688 Transcription of Ptgs2 16 0.69 8.31 7.52
21 INT90097 Localization of PTGS2 15 0.69 6.14 6.63
22 INT59079 Transcription of PTGS2 30 0.72 14.21 6.52
23 INT67656 Positive_regulation of Positive_regulation of PTGS2 12 0.46 4.83 6.17
24 INT78955 Regulation of Gene_expression of Ptgs2 12 0.62 7.22 6.02
25 INT112530 Localization of Ptgs2 13 0.70 7.77 5.86
26 INT52695 Regulation of Ptgs2 20 0.42 8.72 5.71
27 INT73309 Regulation of Negative_regulation of PTGS2 14 0.44 9.55 4.5
28 INT52616 Negative_regulation of Positive_regulation of PTGS2 13 0.43 4.95 4.13
29 INT115773 Negative_regulation of Localization of Ptgs2 6 0.43 2.99 3.81
30 INT53200 Binding of Ptgs2 11 0.48 5.08 3.54
31 INT52694 Negative_regulation of Positive_regulation of Ptgs2 9 0.43 4.72 3.11
32 INT68505 Positive_regulation of Negative_regulation of PTGS2 8 0.49 2.26 2.76
33 INT127176 Transcription of Ptgs2 8 0.58 4.68 2.58
34 INT17846 Binding of Ptgs2 8 0.32 4.66 2.48
35 INT78958 Regulation of Negative_regulation of Ptgs2 6 0.42 2.61 2.3
36 INT97579 Negative_regulation of Localization of PTGS2 2 0.08 2.37 1.99
37 INT77805 Regulation of Gene_expression of Ptgs2 6 0.51 2.7 1.92
38 INT52691 Positive_regulation of Transcription of Ptgs2 5 0.44 3 1.9
39 INT149622 Positive_regulation of Transcription of Ptgs2 3 0.28 2.48 1.46
40 INT190768 Regulation of Positive_regulation of Ptgs2 1 0.04 1.2 1.41
41 INT86823 Regulation of Transcription of PTGS2 3 0.19 1.48 1.4
42 INT135658 Phosphorylation of Ptgs2 2 0.23 1.39 1.34
43 INT101026 Positive_regulation of Negative_regulation of Ptgs2 2 0.35 1.01 1.23
44 INT179372 Positive_regulation of Localization of PTGS2 2 0.38 0.35 1.21
45 INT59078 Positive_regulation of Transcription of PTGS2 5 0.69 2.36 1.17
46 INT62981 Protein_catabolism of PTGS2 5 0.78 1.09 1.11
47 INT64862 Negative_regulation of Negative_regulation of PTGS2 3 0.36 0.76 1.09
48 INT70505 Positive_regulation of Positive_regulation of Ptgs2 4 0.49 2.22 1.08
49 INT83647 Negative_regulation of Negative_regulation of Ptgs2 1 0.28 1.97 1.05
50 INT64177 Negative_regulation of Transcription of PTGS2 4 0.41 1.99 1.03
51 INT68265 Positive_regulation of Negative_regulation of Ptgs2 3 0.46 0.08 0.92
52 INT149624 Regulation of Transcription of Ptgs2 1 0.16 0.84 0.84
53 INT115770 Negative_regulation of Positive_regulation of Ptgs2 4 0.43 0.94 0.79
54 INT120057 Regulation of Localization of PTGS2 1 0.28 0.14 0.78
55 INT71950 Positive_regulation of Binding of PTGS2 2 0.31 0.31 0.74
56 INT78957 Regulation of Transcription of Ptgs2 1 0.17 0.49 0.72
57 INT82544 Regulation of Positive_regulation of PTGS2 4 0.39 1.41 0.71
58 INT127175 Negative_regulation of Transcription of Ptgs2 3 0.47 2.11 0.7
59 INT92341 Localization of Ptgs2 5 0.75 2.04 0.64
60 INT115772 Positive_regulation of Localization of Ptgs2 1 0.46 0.5 0.55
61 INT115771 Positive_regulation of Positive_regulation of Ptgs2 1 0.46 0.5 0.54
62 INT142835 Regulation of Localization of Ptgs2 2 0.25 0.26 0.5
63 INT94036 Negative_regulation of Transcription of Ptgs2 1 0.30 0.52 0.43
64 INT82545 Positive_regulation of Regulation of PTGS2 1 0.19 0.15 0.35
65 INT17849 Negative_regulation of Binding of PTGS2 2 0.38 0.16 0.2
66 INT148274 Negative_regulation of Regulation of PTGS2 1 0.01 0.47 0.19
67 INT87715 Negative_regulation of Negative_regulation of Ptgs2 1 0.16 0.68 0.17
68 INT247598 Regulation of Binding of Ptgs2 1 0.10 1.69 0.16
69 INT129433 Regulation of Binding of PTGS2 1 0.25 1.01 0.14
70 INT52697 Regulation of Positive_regulation of Ptgs2 2 0.27 0.34 0.13
71 INT212801 Phosphorylation of Ptgs2 2 0.22 1.03 0.1
72 INT283729 Protein_catabolism of Ptgs2 1 0.01 0.09 0.08
73 INT17845 Negative_regulation of Binding of Ptgs2 1 0.09 0.08 0.04
74 INT121544 Positive_regulation of Regulation of Ptgs2 1 0.14 0.15 0
75 INT96041 Positive_regulation of Localization of Ptgs2 1 0.17 0.07 0
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