GO:0090400

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Name stress-induced premature senescence
Categary Process
Go Slim No
Go Link GO:0090400
Unique Molecular Interactions 307
Total Molecular Interactions 376
Total Single Events 3350
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for stress-induced premature senescence. They are ordered first by their pain relevance and then by number of times they were reported for stress-induced premature senescence. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT314205 Ngf Positive_regulation of Phosphorylation of Mapk14 1 0.43 1.24 2.3
2 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
3 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 0.34 0.85 1.84
4 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
5 INT314214 Mapk14 Positive_regulation of Ngf 1 0.43 1.97 1.56
6 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
7 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
8 INT314213 Mapk14 Positive_regulation of Agtrap 1 0.04 1.15 1.34
9 INT300864 Ngf Positive_regulation of Mapk14 2 0.60 1.38 1.32
10 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
11 INT314209 Ngf Positive_regulation of Binding of Mapk14 1 0.43 1.48 1.27
12 INT139724 PROC Positive_regulation of MAPK14 1 0.00 1.57 1.25
13 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
14 INT314198 Mapk14 Positive_regulation of Gene_expression of Trpv1 1 0.48 1.09 1.24
15 INT314212 Mapk14 Positive_regulation of Gene_expression of Agtrap 1 0.06 1.09 1.24
16 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
17 INT328742 Il1 Positive_regulation of Mapk14 1 0.01 1.4 1.2
18 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18
19 INT314206 Mapk14 Positive_regulation of Pax3 1 0.08 0.67 1.15
20 INT190771 Gene_expression of Il4 Negative_regulation of Gene_expression of Mapk14 1 0.15 1.14 1.13
21 INT190770 Il4 Negative_regulation of Gene_expression of Mapk14 1 0.20 1.14 1.13
22 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
23 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
24 INT108546 BCL2L10 Regulation of MAPKAPK5 1 0.03 1.22 1.1
25 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
26 INT283934 Phax Negative_regulation of Positive_regulation of Mapk14 1 0.03 2.06 1.09
27 INT108547 AKT1 Regulation of MAPKAPK5 1 0.04 1.2 1.08
28 INT292531 Il10 Negative_regulation of Positive_regulation of Mapk14 1 0.15 1.13 1.06
29 INT154846 Negative_regulation of Mapk14 Negative_regulation of Positive_regulation of Trpv1 1 0.23 0.07 1.05
30 INT352456 Dusp1 Negative_regulation of Mapk14 1 0.03 1.31 1.03
31 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
32 INT283932 Positive_regulation of Mapk14 Regulation of Gene_expression of Trpv1 1 0.14 1.28 0.99
33 INT308169 Negative_regulation of Mapk14 Negative_regulation of Ltp 1 0.01 0.79 0.95
34 INT145853 Casp1 Positive_regulation of Mapk14 1 0.02 0.68 0.93
35 INT318461 Nnat Positive_regulation of Mapk14 1 0.05 0.97 0.92
36 INT352465 Dusp1 Negative_regulation of Gene_expression of Mapk14 1 0.03 1.09 0.92
37 INT302828 Mapkapk5 Positive_regulation of Mapk1 1 0.07 1.38 0.91
38 INT352444 Dusp1 Negative_regulation of Phosphorylation of Mapk14 1 0.03 1.09 0.91
39 INT92404 PSRC1 Regulation of CDKN1A 1 0.33 0.66 0.89
40 INT314207 Ngf Negative_regulation of Phosphorylation of Mapk14 1 0.33 0.4 0.88
41 INT209928 IL1B Positive_regulation of MAPK14 2 0.15 1.69 0.87
42 INT288201 Mapk14 Positive_regulation of Cish 1 0.03 0.06 0.82
43 INT128590 Mapk14 Regulation of Nav1 1 0.21 0.25 0.82
44 INT168648 Positive_regulation of Cx3cr1 Positive_regulation of Phosphorylation of Mapk14 1 0.35 1.51 0.8
45 INT222024 Mapk8 Regulation of Mapk14 2 0.17 0.83 0.79
46 INT168647 Cx3cr1 Positive_regulation of Phosphorylation of Mapk14 1 0.52 1.51 0.79
47 INT302831 Binding of Creb1 and Mapkapk5 1 0.07 1.3 0.79
48 INT196577 Negative_regulation of Mapk14 Negative_regulation of Il6 1 0.13 0.45 0.78
49 INT196574 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il6 1 0.13 0.45 0.78
50 INT196575 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1a 1 0.04 0.44 0.77
51 INT346234 MAP2K6 Positive_regulation of MAPK14 1 0.44 1.65 0.77
52 INT146780 Positive_regulation of Fgfr1 Positive_regulation of Mapk14 1 0.34 0.95 0.77
53 INT262577 Localization of Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.05 0.92 0.75
54 INT128815 Mapk14 Regulation of Gene_expression of Nos2 1 0.21 0.46 0.74
55 INT164783 Positive_regulation of Mapk14 Regulation of Gene_expression of Cx3cr1 1 0.19 0.81 0.68
56 INT155457 Tnfrsf1a Positive_regulation of Mapk14 1 0.20 1.17 0.67
57 INT314199 Mapk14 Regulation of Tnf 1 0.26 0.71 0.67
58 INT148139 Phosphorylation of Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.46 0.98 0.66
59 INT148138 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.64 0.98 0.66
60 INT166299 Binding of Mapk14 and Gpbar1 1 0.13 0.64 0.65
61 INT166302 Negative_regulation of Binding of Mapk14 and Gpbar1 1 0.12 0.64 0.65
62 INT288202 Negative_regulation of Cd14 Positive_regulation of Positive_regulation of Mapk14 1 0.09 1.08 0.64
63 INT165047 Mapk14 Positive_regulation of Gene_expression of Tnf 1 0.73 0.8 0.63
64 INT223155 Binding of Mapk14 and Stat4 1 0.36 0.84 0.63
65 INT148137 Tnf Positive_regulation of Positive_regulation of Mapk14 1 0.46 1 0.63
66 INT166398 CDKN1B Regulation of Gene_expression of CDKN1A 1 0.46 0.83 0.61
67 INT166399 CDKN1A Regulation of Gene_expression of CDKN1B 1 0.46 0.83 0.61
68 INT166395 CDKN1A Regulation of Gene_expression of IFI27 1 0.32 0.83 0.61
69 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
70 INT128811 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Casp1 1 0.06 0.35 0.61
71 INT219280 Mapk14 Positive_regulation of Pla2g2a 1 0.33 0.46 0.61
72 INT166392 IFI27 Regulation of Gene_expression of CDKN1A 1 0.32 0.83 0.61
73 INT308175 Negative_regulation of Mapk14 Negative_regulation of Localization of TNF 1 0.03 0.89 0.61
74 INT314197 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.48 1.16 0.61
75 INT219282 Mapk14 Positive_regulation of Pla2g1b 1 0.18 0.46 0.61
76 INT92403 PSRC1 Regulation of Positive_regulation of CDKN1A 1 0.33 0.45 0.6
77 INT223158 Mapk3 Regulation of Gene_expression of Mapk14 1 0.48 1.33 0.59
78 INT314208 Trap1 Positive_regulation of Mapk14 1 0.10 0.66 0.57
79 INT110032 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il12a 1 0.36 0 0.57
80 INT278694 TNF Positive_regulation of MAPK14 1 0.03 0.79 0.56
81 INT196585 Mapk14 Regulation of TNF 1 0.02 0.36 0.55
82 INT328744 TNF Regulation of Positive_regulation of Mapk14 1 0.02 0.81 0.55
83 INT161251 Ptgs2 Regulation of Mapk14 1 0.16 0.82 0.54
84 INT161250 Trib3 Regulation of Mapk14 1 0.04 0.81 0.54
85 INT171906 MAPK1 Positive_regulation of Gene_expression of MAPK14 1 0.08 1.55 0.52
86 INT313376 Cnr1 Positive_regulation of Phosphorylation of Mapk14 1 0.20 0.38 0.5
87 INT104960 Ephb1 Regulation of Positive_regulation of Mapk14 1 0.15 0.42 0.5
88 INT313375 Cnr2 Positive_regulation of Phosphorylation of Mapk14 1 0.18 0.39 0.5
89 INT104961 Mapk14 Regulation of Positive_regulation of Ephb1 1 0.15 0.42 0.5
90 INT110031 Positive_regulation of Adra2c Positive_regulation of Mapk14 1 0.25 0 0.48
91 INT110030 Adra2c Positive_regulation of Mapk14 1 0.25 0 0.48
92 INT110034 Negative_regulation of Adra2c Positive_regulation of Mapk14 1 0.23 0 0.48
93 INT131504 Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.14 0.2 0.47
94 INT131507 Ngf Positive_regulation of Mapk14 1 0.13 0.2 0.47
95 INT265646 Binding of Mapk1 and Mapk14 1 0.01 1.53 0.46
96 INT254225 Mapk14 Positive_regulation of Mapk8 1 0.02 0.87 0.46
97 INT254216 Mapk14 Positive_regulation of Mapk1 1 0.02 0.87 0.46
98 INT254222 Mapk1 Positive_regulation of Mapk14 1 0.02 0.86 0.46
99 INT313378 Trib3 Regulation of Phosphorylation of Mapk14 1 0.01 0.37 0.44
100 INT278964 MAPK14 Negative_regulation of Localization of EPHB2 1 0.15 0.47 0.43
101 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
102 INT264479 Il1a Positive_regulation of Gene_expression of Mapk14 1 0.02 0 0.43
103 INT124088 Rab38 Negative_regulation of Mapk14 1 0.00 0.89 0.42
104 INT331799 IL8 Negative_regulation of Mapk14 1 0.01 1.6 0.42
105 INT131506 Rac1 Regulation of Positive_regulation of Mapk14 1 0.19 0.39 0.42
106 INT319313 Socs4 Positive_regulation of Mapk14 1 0.02 0.68 0.41
107 INT95402 Mapk14 Regulation of Positive_regulation of Trib3 1 0.06 0.19 0.41
108 INT302824 Mapkapk5 Positive_regulation of Phosphorylation of Hspb2 1 0.11 0.64 0.4
109 INT152238 Mapk14 Positive_regulation of Localization of Tlr4 1 0.29 0.13 0.39
110 INT152241 Mapk14 Positive_regulation of Localization of Nfkb1 1 0.25 0.13 0.39
111 INT264482 Il1a Positive_regulation of Phosphorylation of Mapk14 1 0.02 0 0.37
112 INT264481 Il1a Positive_regulation of Mapk14 1 0.02 0 0.37
113 INT278970 MAPK14 Positive_regulation of Gene_expression of IL8 1 0.11 0.66 0.37
114 INT278938 MAPK14 Positive_regulation of Gene_expression of PRKCA 1 0.05 0.65 0.37
115 INT278966 MAPK14 Positive_regulation of Gene_expression of LEP 1 0.16 0.62 0.36
116 INT288208 Binding of Mapk14 and Positive_regulation of Akt1 1 0.01 0.42 0.35
117 INT223874 Negative_regulation of Mapk14 Negative_regulation of Positive_regulation of Ltp 1 0.13 0 0.34
118 INT346228 MAP2K6 Positive_regulation of Positive_regulation of MAPK14 1 0.44 0.68 0.34
119 INT346229 PREP Positive_regulation of MAPK14 1 0.13 0.63 0.34
120 INT119262 PPM1E Negative_regulation of Positive_regulation of CDKN1A 1 0.01 0.96 0.33
121 INT346236 Binding of MAPK14 and MAP2K6 1 0.32 0.65 0.33
122 INT302830 Mapk14 Regulation of Mapkapk5 1 0.12 0.53 0.33
123 INT346231 Binding of MAPK14 and MAP2K3 1 0.33 0.65 0.33
124 INT297972 MAPK14 Negative_regulation of ING5 1 0.21 1.67 0.33
125 INT255944 MAPK14 Positive_regulation of Tauph 1 0.00 0.1 0.32
126 INT259639 MAPK14 Regulation of Gene_expression of IL8 1 0.02 1.2 0.32
127 INT255945 MAPK14 Positive_regulation of Rps6ka5 1 0.06 0.1 0.32
128 INT255946 MAPK14 Positive_regulation of Map3k1 1 0.04 0.1 0.32
129 INT346235 IL1B Positive_regulation of Gene_expression of MAPK14 1 0.15 0.64 0.32
130 INT288198 Binding of Tlr4 and Mapk14 1 0.01 0.63 0.31
131 INT288203 Binding of Cd14 and Mapk14 1 0.08 0.63 0.31
132 INT112799 Positive_regulation of CASP1 Positive_regulation of MAPK14 1 0.02 0.16 0.3
133 INT167982 Mapk14 Negative_regulation of gr 1 0.02 0.45 0.29
134 INT196584 Binding of Mapk14 and NeuN 1 0.02 0.39 0.27
135 INT123663 F2R Positive_regulation of MAPK14 1 0.12 0.42 0.26
136 INT123662 Negative_regulation of F2R Positive_regulation of MAPK14 1 0.08 0.42 0.26
137 INT171907 MAPK8 Positive_regulation of Gene_expression of MAPK14 1 0.06 0.77 0.26
138 INT123661 COL7A1 Positive_regulation of MAPK14 1 0.08 0.42 0.26
139 INT171911 MAPK8IP3 Positive_regulation of Gene_expression of MAPK14 1 0.05 0.77 0.26
140 INT270216 Mapk14 Positive_regulation of Mknk1 1 0.10 0.5 0.26
141 INT225160 Negative_regulation of Binding of CDK2 and CDKN1A 1 0.35 0 0.25
142 INT260739 Mapk14 Regulation of Positive_regulation of Sp1 1 0.01 1.06 0.25
143 INT312546 Ros1 Positive_regulation of Positive_regulation of Mapk14 1 0.00 0.87 0.25
144 INT260743 Mapk14 Regulation of Gene_expression of Il10 1 0.04 0.99 0.24
145 INT179230 Binding of MAPK14 and GSR 1 0.03 0.5 0.23
146 INT112794 CASP1 Positive_regulation of MAPK14 1 0.02 0.16 0.23
147 INT327313 Positive_regulation of Mapk14 Positive_regulation of Phosphorylation of Khsrp 1 0.09 0.24 0.22
148 INT112793 IL4I1 Positive_regulation of Positive_regulation of MAPK14 1 0.04 0 0.22
149 INT297965 MAPK14 Negative_regulation of GADD45A 1 0.05 1 0.21
150 INT266410 Binding of HMGB1 and Mapk14 1 0.03 0.91 0.2
151 INT208942 Positive_regulation of Mapk14 Positive_regulation of Positive_regulation of Jun 1 0.10 0.42 0.2
152 INT212084 NOXO1 Positive_regulation of CDKN1A 1 0.06 0.53 0.19
153 INT284446 Dep1 Positive_regulation of Mapk14 1 0.01 0.58 0.18
154 INT300305 Mapk14 Positive_regulation of Gene_expression of Ctgf 1 0.19 1.25 0.17
155 INT119263 Binding of CDKN1A and PPM1E 1 0.01 0.46 0.17
156 INT226518 Il1rl1 Positive_regulation of MAPK14 1 0.04 0.2 0.15
157 INT228216 Positive_regulation of Mapk14 Regulation of Gene_expression of Tlr2 1 0.09 1.11 0.15
158 INT329985 Positive_regulation of Prkaca Positive_regulation of Positive_regulation of Mapk14 1 0.15 0.87 0.15
159 INT327324 Mapk6 Positive_regulation of Mapk14 1 0.01 0.29 0.15
160 INT226520 Il1rl1 Positive_regulation of Gene_expression of MAPK14 1 0.03 0.2 0.15
161 INT327329 S100a8 Positive_regulation of Mapk14 1 0.00 0.36 0.14
162 INT123192 Bmp6 Positive_regulation of CDKN1A 1 0.18 0.61 0.14
163 INT327309 Il1 Positive_regulation of Mapk14 1 0.01 0.36 0.14
164 INT302144 CDKN2A Regulation of CDKN1A 1 0.11 0.51 0.14
165 INT327319 Binding of Mapk14 and Ttpa 1 0.01 0.34 0.14
166 INT272927 Mapk14 Positive_regulation of Gene_expression of TNF 1 0.16 0.53 0.14
167 INT193789 SDF2L1 Positive_regulation of CDKN1A 1 0.00 0.68 0.13
168 INT224677 L1cam Positive_regulation of Positive_regulation of Mapk14 1 0.00 0.39 0.13
169 INT193785 SDF2L1 Positive_regulation of Gene_expression of CDKN1A 1 0.00 0.68 0.13
170 INT327318 Mapk14 Regulation of Localization of Elavl1 1 0.09 0.42 0.13
171 INT295480 MAPK14 Positive_regulation of Localization of TNF 1 0.08 1.08 0.12
172 INT327330 Mapk14 Regulation of Il1 1 0.01 0.33 0.12
173 INT297967 MAPK14 Negative_regulation of SCUBE3 1 0.01 0.67 0.12
174 INT308004 Rsph1 Positive_regulation of Mapk14 1 0.02 0.61 0.12
175 INT331797 Ugcg Regulation of Negative_regulation of Mapk14 1 0.01 1.03 0.11
176 INT331794 Binding of Ugcg and Regulation of Negative_regulation of Mapk14 1 0.01 1.05 0.11
177 INT291260 Map3k8 Regulation of Gene_expression of MAPK14 1 0.07 0.52 0.11
178 INT300313 TGFB1 Positive_regulation of Mapk14 1 0.01 1.5 0.11
179 INT300306 Agt Positive_regulation of Mapk14 1 0.14 1.51 0.11
180 INT314590 Binding of Ifnar1 and Positive_regulation of Mapk14 1 0.16 0 0.1
181 INT260944 Mapk14 Positive_regulation of Transcription of Aqp3 1 0.29 0.21 0.09
182 INT202402 Binding of Akt1 and Mapk14 1 0.11 0.13 0.09
183 INT260947 Mapk14 Positive_regulation of Aqp3 1 0.29 0.21 0.09
184 INT202406 Binding of Osm and Mapk14 1 0.21 0.13 0.09
185 INT260945 Mapk14 Positive_regulation of Gene_expression of Aqp3 1 0.29 0.21 0.09
186 INT202399 Binding of Mapk14 and Racgap1 1 0.07 0.13 0.09
187 INT202393 Binding of Mapk14 and Nexn 1 0.03 0.13 0.09
188 INT202401 Binding of Map3k3 and Mapk14 1 0.41 0.13 0.09
189 INT237922 TNFSF10 Positive_regulation of CDKN1A 1 0.09 3.28 0.08
190 INT218662 Olr811 Positive_regulation of Positive_regulation of Mapk14 1 0.00 0.54 0.08
191 INT268925 Igfbp2 Negative_regulation of Phosphorylation of Mapk14 1 0.01 0.35 0.08
192 INT302158 CDKN1A Regulation of CDKN2A 1 0.04 0.26 0.08
193 INT300304 Positive_regulation of Mapk14 Positive_regulation of Agt 1 0.14 1.5 0.08
194 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07
195 INT182268 Negative_regulation of MAPK14 Negative_regulation of Gene_expression of EDN1 1 0.22 0.31 0.07
196 INT231512 Positive_regulation of Tlr4 Positive_regulation of Mapk14 1 0.06 0.15 0.07
197 INT325275 IL1RAP Positive_regulation of Mapk14 1 0.13 0 0.07
198 INT182274 MAPK14 Negative_regulation of Gene_expression of EDN1 1 0.22 0.31 0.07
199 INT231513 Tlr4 Positive_regulation of Positive_regulation of Mapk14 1 0.06 0.15 0.07
200 INT193783 ITIH4 Regulation of Gene_expression of CDKN1A 1 0.03 0.55 0.07

Single Events

The table below shows the top 100 pain related interactions that have been reported for stress-induced premature senescence. They are ordered first by their pain relevance and then by number of times they were reported in stress-induced premature senescence. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61
2 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46
3 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51
4 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79
5 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59
6 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32
7 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42
8 INT97702 Positive_regulation of Phosphorylation of Mapk14 69 0.69 49.21 36.81
9 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08
10 INT106272 Positive_regulation of Positive_regulation of Mapk14 39 0.70 32.08 24.71
11 INT86534 Positive_regulation of MAPK14 81 0.62 57.81 23.62
12 INT99069 Positive_regulation of Gene_expression of Mapk14 42 0.53 29.84 23.16
13 INT69322 Negative_regulation of MAPK14 70 0.54 42.92 22.71
14 INT171924 Gene_expression of MAPK14 60 0.65 54.38 21.68
15 INT125411 Negative_regulation of Phosphorylation of Mapk14 31 0.57 18.55 19.98
16 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3
17 INT111531 Negative_regulation of Phosphorylation of Mapk14 37 0.50 20 17.68
18 INT96911 Positive_regulation of Phosphorylation of Mapk14 46 0.70 43.03 15.15
19 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74
20 INT104954 Negative_regulation of Positive_regulation of Mapk14 29 0.58 17.71 13.31
21 INT110025 Positive_regulation of Positive_regulation of Mapk14 39 0.63 20.67 12.71
22 INT117113 Regulation of Mapk14 28 0.45 16.71 11.99
23 INT118906 Regulation of Mapk14 21 0.44 17.95 11.63
24 INT103923 Negative_regulation of Positive_regulation of Mapk14 23 0.53 13.95 10.64
25 INT110178 Phosphorylation of MAPK14 40 0.68 19.38 10.37
26 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69
27 INT159750 Negative_regulation of Gene_expression of Mapk14 15 0.40 10.88 7.81
28 INT128695 Regulation of Gene_expression of Mapk14 14 0.44 11.49 7.14
29 INT128587 Localization of Mapk14 15 0.81 8.41 6.1
30 INT104330 Negative_regulation of CDKN1A 57 0.58 39.93 5.88
31 INT176524 Binding of Mapk14 19 0.43 12.54 5.21
32 INT126047 Regulation of Phosphorylation of Mapk14 7 0.60 5.05 5.03
33 INT160055 Localization of CDKN1A 15 0.78 12.56 4.83
34 INT171472 Binding of Mapk14 10 0.36 6.79 4.83
35 INT117920 Regulation of MAPK14 14 0.38 8.75 4.31
36 INT110024 Negative_regulation of Gene_expression of Mapk14 19 0.42 7.83 4.21
37 INT117921 Positive_regulation of Positive_regulation of MAPK14 9 0.44 9.93 4.18
38 INT131782 Regulation of Positive_regulation of Mapk14 7 0.43 2.68 4.02
39 INT110021 Positive_regulation of Gene_expression of Mapk14 29 0.46 19.06 3.86
40 INT82796 Regulation of CDKN1A 22 0.53 9.83 3.33
41 INT75505 Regulation of Gene_expression of CDKN1A 24 0.60 12.24 3.07
42 INT173179 Binding of MAPK14 13 0.29 4.51 2.92
43 INT155453 Protein_catabolism of Mapk14 6 0.36 4.24 2.85
44 INT75499 Positive_regulation of Positive_regulation of CDKN1A 12 0.60 7.28 2.84
45 INT96901 Regulation of Negative_regulation of Mapk14 3 0.45 4.07 2.79
46 INT202341 Gene_expression of Mapkapk5 3 0.46 3.67 2.43
47 INT110179 Negative_regulation of Phosphorylation of MAPK14 11 0.36 5.25 2.38
48 INT173647 Positive_regulation of Gene_expression of MAPK14 15 0.39 7.54 2.05
49 INT118907 Negative_regulation of Negative_regulation of Mapk14 2 0.57 2.09 1.77
50 INT152894 Regulation of Positive_regulation of Mapk14 9 0.45 6.01 1.74
51 INT168686 Transcription of Mapk14 6 0.52 2.96 1.67
52 INT173173 Regulation of Positive_regulation of MAPK14 6 0.38 2.59 1.64
53 INT104331 Negative_regulation of Gene_expression of CDKN1A 24 0.57 13.68 1.63
54 INT302790 Positive_regulation of Mapkapk5 1 0.25 2.6 1.55
55 INT182297 Positive_regulation of Phosphorylation of MAPK14 7 0.42 3.36 1.53
56 INT173654 Localization of MAPK14 12 0.62 3.16 1.43
57 INT202365 Regulation of Gene_expression of Mapk14 6 0.45 4.89 1.26
58 INT112823 Negative_regulation of Positive_regulation of MAPK14 5 0.36 1.49 1.22
59 INT126525 Regulation of Negative_regulation of Mapk14 2 0.41 0.81 1.11
60 INT108551 Gene_expression of MAPKAPK5 1 0.15 1.23 1.1
61 INT108553 Negative_regulation of Gene_expression of MAPKAPK5 1 0.09 1.23 1.1
62 INT108552 Regulation of MAPKAPK5 1 0.10 1.19 1.08
63 INT178391 Localization of Mapk14 9 0.68 5.27 0.97
64 INT145028 Positive_regulation of Localization of Mapk14 2 0.20 0.85 0.96
65 INT231494 Regulation of Phosphorylation of Mapk14 2 0.24 2.59 0.93
66 INT194875 Regulation of Negative_regulation of MAPK14 1 0.04 2.39 0.91
67 INT107161 Positive_regulation of MAPKAPK5 2 0.16 1.15 0.82
68 INT302768 Regulation of Mapkapk5 1 0.24 1.6 0.82
69 INT219268 Negative_regulation of Negative_regulation of Mapk14 2 0.38 0.99 0.8
70 INT302792 Transcription of Mapkapk5 1 0.38 1.37 0.8
71 INT146521 Negative_regulation of Positive_regulation of CDKN1A 6 0.42 3.29 0.79
72 INT302771 Negative_regulation of Mapkapk5 1 0.23 1.46 0.77
73 INT314190 Negative_regulation of Localization of Mapk14 1 0.36 0.91 0.69
74 INT139840 Positive_regulation of Negative_regulation of MAPK14 2 0.21 1.55 0.67
75 INT209936 Negative_regulation of Gene_expression of MAPK14 7 0.20 4.95 0.53
76 INT121027 Regulation of Phosphorylation of MAPK14 2 0.38 1.1 0.46
77 INT173625 Positive_regulation of Localization of MAPK14 3 0.17 1.05 0.44
78 INT179170 Protein_catabolism of MAPK14 3 0.43 0.88 0.43
79 INT231499 Positive_regulation of Negative_regulation of Mapk14 3 0.24 1.58 0.43
80 INT255902 Positive_regulation of Binding of MAPK14 1 0.17 0.93 0.42
81 INT125592 Negative_regulation of Negative_regulation of CDKN1A 2 0.42 2.07 0.41
82 INT302793 Positive_regulation of Gene_expression of Mapkapk5 1 0.25 0.68 0.41
83 INT302806 Positive_regulation of Transcription of Mapkapk5 1 0.25 0.69 0.4
84 INT82797 Transcription of CDKN1A 11 0.69 8.01 0.32
85 INT207377 Positive_regulation of Regulation of Mapk14 1 0.20 0.67 0.32
86 INT119269 Binding of CDKN1A 14 0.47 8.82 0.31
87 INT123529 Phosphorylation of CDKN1A 8 0.80 5.69 0.29
88 INT301057 Regulation of Transcription of Mapk14 1 0.25 0.5 0.29
89 INT255923 Positive_regulation of Regulation of MAPK14 1 0.17 0.41 0.28
90 INT345923 Positive_regulation of Transcription of Mapk14 1 0.07 0.41 0.25
91 INT225177 Regulation of Negative_regulation of CDKN1A 1 0.39 0.26 0.25
92 INT267610 Negative_regulation of Negative_regulation of MAPK14 1 0.03 1.08 0.15
93 INT250776 Protein_catabolism of Mapk14 3 0.52 1.04 0.14
94 INT123181 Positive_regulation of Negative_regulation of CDKN1A 1 0.49 0.6 0.14
95 INT346252 Regulation of Gene_expression of MAPK14 1 0.38 0 0.09
96 INT178395 Transcription of Mapk14 6 0.61 0.47 0.07
97 INT176262 Positive_regulation of Phosphorylation of CDKN1A 3 0.49 2.12 0.06
98 INT178408 Positive_regulation of Localization of Mapk14 2 0.42 0.87 0.04
99 INT182288 Negative_regulation of Binding of MAPK14 1 0.21 0.08 0.04
100 INT182280 Negative_regulation of Localization of MAPK14 1 0.21 0.39 0.04
101 INT224295 Protein_catabolism of CDKN1A 1 0.12 0.55 0.03
102 INT288182 Regulation of Transcription of Mapk14 1 0.40 0.33 0.03
103 INT288195 Negative_regulation of Transcription of Mapk14 1 0.08 0.06 0.03
104 INT288187 Positive_regulation of Transcription of Mapk14 1 0.09 0.06 0.03
105 INT271100 Regulation of Positive_regulation of CDKN1A 2 0.44 1.52 0
106 INT234750 Regulation of Regulation of CDKN1A 1 0.09 0.45 0
107 INT202368 Phosphorylation of Mapkapk5 1 0.80 0.2 0
108 INT225184 Positive_regulation of Binding of CDKN1A 1 0.43 0.87 0
109 INT250716 Positive_regulation of Transcription of CDKN1A 1 0.18 0.48 0
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