GO:0090403

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Name oxidative stress-induced premature senescence
Categary Process
Go Slim No
Go Link GO:0090403
Unique Molecular Interactions 216
Total Molecular Interactions 257
Total Single Events 1986
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for oxidative stress-induced premature senescence. They are ordered first by their pain relevance and then by number of times they were reported for oxidative stress-induced premature senescence. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
3 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
4 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
5 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
6 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
7 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
8 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
9 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
10 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
11 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32
12 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
13 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31
14 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
15 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
16 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
17 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 0.05 0.75 0.28
18 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
19 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28
20 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
21 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
22 INT216128 EGR1 Regulation of TP53 1 0.11 0.21 0.27
23 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26
24 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26
25 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
26 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
27 INT352893 PTGDS Regulation of TP53 1 0.16 1.02 0.26
28 INT125516 TP53 Regulation of GDF15 1 0.10 0.47 0.26
29 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
30 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
31 INT156879 Gene_expression of TP53 Negative_regulation of Positive_regulation of PDF 1 0.45 0.9 0.24
32 INT181900 TP53 Negative_regulation of Gene_expression of NOS1 1 0.03 0.94 0.24
33 INT156881 TP53 Positive_regulation of Positive_regulation of PDF 1 0.49 0.89 0.24
34 INT229177 IFRD1 Regulation of TP53 1 0.13 0.68 0.23
35 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22
36 INT229178 TP53 Regulation of ICAM1 1 0.07 0.9 0.21
37 INT156882 Binding of TP53 and PDF 1 0.39 0.77 0.21
38 INT156880 TP53 Positive_regulation of Gene_expression of PDF 1 0.49 0.75 0.21
39 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 0.33 0.93 0.2
40 INT193787 Positive_regulation of CXCR4 Positive_regulation of Positive_regulation of TP53 1 0.03 0.71 0.19
41 INT142853 Binding of TP53 and WISP2 1 0.33 1.43 0.19
42 INT102804 NFKB1 Regulation of TP53 1 0.35 0.77 0.17
43 INT102803 NFKB1 Regulation of Gene_expression of TP53 1 0.35 0.77 0.17
44 INT91812 Binding of FASLG and TP53 1 0.04 1.1 0.16
45 INT91811 Binding of FAS and TP53 1 0.21 1.1 0.16
46 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15
47 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
48 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
49 INT132148 LTF Positive_regulation of TP53 1 0.44 0.56 0.13
50 INT103561 Binding of TP53 and Mc1r 1 0.03 1 0.13
51 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
52 INT83370 Binding of HRAS and TP53 1 0.30 0.59 0.11
53 INT266386 Binding of S100a1 and Trp53 1 0.03 0.64 0.1
54 INT193782 Binding of TP53 and SDF2L1 1 0.00 0.67 0.1
55 INT262522 Binding of Trp53 and Foxo4 1 0.05 0.7 0.1
56 INT310743 TP53 Regulation of BAX 1 0.09 1.11 0.1
57 INT326126 Binding of S100A1 and TP53 1 0.04 1.34 0.09
58 INT352611 Trp53 Negative_regulation of Localization of Gli1 1 0.23 1.2 0.09
59 INT302168 YWHAQ Regulation of TP53 1 0.01 0.41 0.09
60 INT265466 CSPG4 Regulation of Phosphorylation of TP53 1 0.09 0.15 0.09
61 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
62 INT266394 Binding of S100a4 and Trp53 1 0.03 0.59 0.08
63 INT266390 Binding of S100a6 and Trp53 1 0.04 0.51 0.07
64 INT245296 Trp53 Regulation of Gadd45a 1 0.05 0.43 0.07
65 INT266398 Binding of S100b and Trp53 1 0.06 0.92 0.07
66 INT302143 TP53 Regulation of Positive_regulation of CASP3 1 0.01 0.69 0.06
67 INT302155 TP53 Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06
68 INT204074 Tp53 Positive_regulation of Cdkn1b 1 0.00 0.59 0.06
69 INT140291 ROS1 Positive_regulation of TP53 1 0.52 1.27 0.06
70 INT265459 Phosphorylation of TP53 Positive_regulation of Localization of CASP9 1 0.17 1.16 0.05
71 INT352618 Tpt1 Regulation of Trp53 1 0.06 0.54 0.05
72 INT286768 Binding of Trp53 and Tusc2 1 0.07 1.1 0.05
73 INT352621 Gli1 Negative_regulation of Trp53 1 0.32 0.56 0.05
74 INT181601 Binding of TP53 and WT1 1 0.30 0.9 0.05
75 INT265454 Phosphorylation of TP53 Positive_regulation of CASP9 1 0.17 1.16 0.05
76 INT345181 Gpr87 Regulation of Trp53 1 0.01 0.42 0.05
77 INT193788 ITIH4 Regulation of Phosphorylation of TP53 1 0.07 0.45 0.05
78 INT352612 Trp53 Negative_regulation of Cd44 1 0.24 1.01 0.04
79 INT348022 Binding of Jun and Trp53 1 0.07 0.46 0.04
80 INT172214 BAX Positive_regulation of TP53 1 0.09 0.37 0.04
81 INT329230 Negative_regulation of ATIC Positive_regulation of Trp53 1 0.00 0.58 0.04
82 INT329228 ATIC Positive_regulation of Trp53 1 0.01 0.58 0.04
83 INT352619 Bcl2l12 Negative_regulation of Trp53 1 0.27 0.94 0.04
84 INT352613 Binding of Trp53 and Bcl2l12 1 0.23 0.94 0.04
85 INT170457 RASGRP1 Regulation of TP53 1 0.02 0.58 0.04
86 INT201726 Mapk8 Positive_regulation of Positive_regulation of Trp53 1 0.00 0.41 0.04
87 INT260267 Binding of TFAM and TP53 2 0.37 2.1 0.03
88 INT355036 CKAP4 Regulation of Positive_regulation of TP53 1 0.08 0.4 0.03
89 INT266903 Binding of Sod2 and Trp53 1 0.05 0 0.03
90 INT211873 TP53 Positive_regulation of Transcription of CD40 1 0.03 1.44 0.03
91 INT234625 TP53 Positive_regulation of IGFBP3 1 0.29 0.74 0.03
92 INT352624 Trp53 Negative_regulation of CEL 1 0.01 1.01 0.03
93 INT265464 CSPG4 Regulation of Gene_expression of TP53 1 0.09 0.23 0.03
94 INT314686 TP53 Regulation of Gene_expression of MDM2 1 0.21 0.96 0.03
95 INT229098 Binding of TP53 and IER3 1 0.01 1.47 0.03
96 INT314677 TP53 Regulation of Positive_regulation of CDKN2A 1 0.27 0.97 0.03
97 INT276389 Binding of Trp53 and KRT20 1 0.01 0.97 0.03
98 INT302134 TP53 Positive_regulation of Transcription of CDKN1A 1 0.04 0.28 0.03
99 INT314690 TP53 Regulation of Gene_expression of ZBTB7A 1 0.33 0.97 0.03
100 INT211872 TP53 Positive_regulation of CD40 1 0.03 1.44 0.03
101 INT242015 Binding of Mdm2 and Trp53 3 0.16 5.74 0
102 INT352615 Binding of Mdm4 and Trp53 1 0.30 1.36 0
103 INT304029 Binding of PTEN and TP53 1 0.35 0.62 0
104 INT315395 Regulation of Binding of IFNA1 and Tp53 1 0.00 0.46 0
105 INT304020 AR Regulation of TP53 1 0.24 1.11 0
106 INT315221 Tpt1 Regulation of Positive_regulation of Trp53 1 0.33 1.04 0
107 INT203901 HIVEP1 Positive_regulation of Gene_expression of TP53 1 0.04 0.86 0
108 INT232006 Binding of Trp53 and Tsp1 1 0.06 0.75 0
109 INT333685 Binding of Trp53 and Hdac1 1 0.26 0.55 0
110 INT333688 Trp53 Positive_regulation of Bcl2 1 0.45 2.51 0
111 INT304022 Binding of PIK3CG and TP53 1 0.10 0.72 0
112 INT333690 Hr Negative_regulation of Transcription of Trp53 1 0.23 0.51 0
113 INT217776 TP53 Regulation of MITF 1 0.00 1.28 0
114 INT334322 Binding of RB1 and TP53 1 0.34 2 0
115 INT342007 Mta1 Regulation of Trp53 1 0.15 0.15 0
116 INT179095 Myc Positive_regulation of Gene_expression of Trp53 1 0.43 0.83 0
117 INT315397 Binding of IFNA1 and Tp53 1 0.00 0.43 0
118 INT333689 Hr Positive_regulation of Protein_catabolism of Trp53 1 0.25 1.71 0
119 INT345489 TP53 Positive_regulation of PMAIP1 1 0.05 0.6 0
120 INT286044 Wwox Positive_regulation of Tp53 1 0.05 0.63 0
121 INT347162 MDM2 Negative_regulation of TP53 1 0.02 1.09 0
122 INT235645 TP53 Regulation of EPHA2 1 0.10 0.97 0
123 INT241256 TP53 Regulation of OPCML 1 0.12 1.31 0
124 INT305542 Binding of Rb1 and Trp53 1 0.00 0.9 0
125 INT352625 Trp53 Regulation of CEL 1 0.00 0.71 0
126 INT320714 Gene_expression of MDM2 Negative_regulation of TP53 1 0.16 0.88 0
127 INT333455 ATM Positive_regulation of TP53 1 0.18 0 0
128 INT204234 Binding of CDKN2A and TP53 1 0.43 1.27 0
129 INT177793 EGR1 Positive_regulation of Negative_regulation of TP53 1 0.18 0.44 0
130 INT284232 Binding of TP53 and HNRNPUL1 1 0.26 0.88 0
131 INT304028 MDM2 Regulation of TP53 1 0.19 1.11 0
132 INT306256 MDM2 Negative_regulation of Positive_regulation of TP53 1 0.23 0.44 0
133 INT278186 Binding of TP53 and GOPC 1 0.02 0.85 0
134 INT337708 Naf1 Regulation of Gene_expression of Tp53 1 0.09 0.22 0
135 INT345337 Binding of TP53 and BCC1 1 0.11 1.05 0
136 INT304018 Regulation of Binding of PIK3CG and TP53 1 0.12 0.73 0
137 INT353437 Negative_regulation of Trp53 Positive_regulation of Gene_expression of Cdkn2a 1 0.24 0.59 0
138 INT268513 MIR34A Regulation of Gene_expression of TP53 1 0.00 0.9 0
139 INT172604 Binding of EP300 and TP53 1 0.00 0 0
140 INT193118 Trp53 Regulation of Gene_expression of Birc5 1 0.19 0.86 0
141 INT225564 Ncoa6 Regulation of Trp53 1 0.04 0.93 0
142 INT304025 Binding of PIK3CA and TP53 1 0.30 0.67 0
143 INT352617 Mdm2 Positive_regulation of Positive_regulation of Trp53 1 0.20 2.56 0
144 INT337639 TP53 Regulation of Gene_expression of MIR34A 1 0.08 1.19 0
145 INT350983 TP53 Regulation of VEGFA 1 0.03 0.61 0
146 INT276380 Binding of PIM1 and Trp53 1 0.01 0.66 0
147 INT337680 Binding of TP53 and Scrib 1 0.03 1.6 0
148 INT325375 Binding of Tp53 and Positive_regulation of Positive_regulation of PARP1 1 0.05 0.59 0
149 INT187575 TP53 Regulation of Gene_expression of Birc5 1 0.05 1.1 0
150 INT217781 Binding of MITF and TP53 1 0.00 1.2 0
151 INT267258 Binding of TP53 and BCL11B 1 0.09 0.42 0
152 INT305540 Binding of Trp53 and Tpt1 1 0.07 0.9 0
153 INT333697 Binding of Hr and Trp53 1 0.19 0.56 0
154 INT113343 Phosphorylation of TP53 Positive_regulation of Gene_expression of BAX 1 0.11 0.14 0
155 INT179090 Positive_regulation of Myc Regulation of Gene_expression of Trp53 1 0.23 0.69 0
156 INT301466 Smyd2 Negative_regulation of Binding of Trp53 1 0.20 0.3 0
157 INT338969 Binding of ING1 and TP53 1 0.13 0.98 0
158 INT235650 TP53 Regulation of EFNA1 1 0.06 0.97 0
159 INT301468 Smyd2 Negative_regulation of Trp53 1 0.20 0.31 0
160 INT337637 SIRT1 Negative_regulation of TP53 1 0.23 1.49 0
161 INT351977 Binding of Tp53 and Trib3 1 0.01 0.79 0
162 INT119045 HIF1A Regulation of Regulation of TP53 1 0.09 1.06 0
163 INT333695 Trp53 Positive_regulation of Localization of Bcl2l1 1 0.23 1.33 0
164 INT119046 HIF1A Regulation of TP53 1 0.05 1.06 0
165 INT333693 Hr Negative_regulation of Gene_expression of Trp53 1 0.27 0.9 0
166 INT338971 ING1 Regulation of TP53 1 0.09 1.02 0
167 INT175399 Binding of TP53 and SACM1L 1 0.00 2.37 0
168 INT284231 Binding of TP53 and C4orf3 1 0.02 0.88 0
169 INT304019 Binding of AKT1 and TP53 1 0.27 0.72 0
170 INT217787 Binding of TP53 and MIR208A 1 0.21 0.5 0
171 INT333681 Trp53 Regulation of Negative_regulation of Bax 1 0.15 1.17 0
172 INT333691 Trp53 Positive_regulation of Bcl2l1 1 0.23 1.33 0
173 INT300307 Binding of Tp53 and Sirt1 1 0.24 0.98 0
174 INT305541 Binding of Bcl2 and Trp53 1 0.05 0.9 0
175 INT187574 Binding of TP53 and Birc5 1 0.04 1.27 0
176 INT314745 Binding of TP53 and Brca1 1 0.18 1.17 0
177 INT189956 TP53 Positive_regulation of Gene_expression of Pttg1 1 0.06 1.21 0
178 INT351976 Binding of Tp53 and Stk11 1 0.13 2.3 0
179 INT286029 Binding of Tp53 and Atf2 1 0.03 0.33 0
180 INT305539 Binding of Mki67 and Trp53 1 0.20 0.91 0
181 INT172605 Positive_regulation of Binding of EP300 and TP53 1 0.00 0 0
182 INT352614 Negative_regulation of Binding of Mdm2 and Trp53 1 0.19 1.16 0
183 INT314691 ERBB2 Negative_regulation of TP53 1 0.28 1.23 0
184 INT236468 TP53 Positive_regulation of Protein_catabolism of SNRPB 1 0.00 0.52 0
185 INT294428 PSEN2 Regulation of Gene_expression of Tp53 1 0.49 0.86 0
186 INT294429 PSEN2 Negative_regulation of Tp53 1 0.46 1.03 0
187 INT324908 TP53 Regulation of Gene_expression of BAX 1 0.47 1.33 0
188 INT238390 ELANE Positive_regulation of Gene_expression of TP53 1 0.04 0.42 0
189 INT287874 Binding of TCF4 and TP53 1 0.02 0.54 0
190 INT338972 Binding of CDKN1A and TP53 1 0.10 0.98 0
191 INT217774 TP53 Regulation of TSC1 1 0.02 1.28 0
192 INT315054 TP53 Positive_regulation of MIR34A 1 0.02 0.47 0
193 INT342251 Binding of Trp53 and Tymp 1 0.21 1.01 0
194 INT305336 TP53 Negative_regulation of Phosphorylation of RB1 1 0.29 0.96 0
195 INT305543 Binding of Top2a and Trp53 1 0.37 0.91 0
196 INT252789 TP53 Regulation of ROS1 1 0.02 0 0
197 INT304017 Regulation of Binding of AKT1 and TP53 1 0.32 0.73 0
198 INT333687 Trp53 Positive_regulation of Localization of Bcl2 1 0.45 1.24 0
199 INT333459 TP53 Positive_regulation of CHEK1 1 0.09 0 0
200 INT301465 Mdm4 Negative_regulation of Trp53 1 0.13 0.35 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for oxidative stress-induced premature senescence. They are ordered first by their pain relevance and then by number of times they were reported in oxidative stress-induced premature senescence. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
2 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
3 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
4 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
5 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
6 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
7 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
8 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
9 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
10 INT60585 Regulation of TP53 59 0.59 54.55 5.21
11 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
12 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
13 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
14 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
15 INT8103 Binding of TP53 46 0.44 40.2 2.96
16 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
17 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
18 INT55952 Transcription of TP53 16 0.61 12.14 2.36
19 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
20 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
21 INT65855 Localization of TP53 18 0.76 17.08 1.89
22 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
23 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
24 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
25 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
26 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
27 INT172953 Binding of Trp53 33 0.37 20.76 1.41
28 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
29 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
30 INT145221 Binding of Tp53 10 0.37 8.59 1.37
31 INT174156 Localization of Trp53 16 0.72 13.52 1.18
32 INT116436 Negative_regulation of Phosphorylation of TP53 2 0.40 0.94 1.16
33 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
34 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
35 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
36 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75
37 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
38 INT162470 Negative_regulation of Protein_catabolism of TP53 1 0.32 1.24 0.74
39 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6
40 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
41 INT286035 Negative_regulation of Gene_expression of Tp53 5 0.32 6.2 0.49
42 INT139976 Regulation of Tp53 7 0.44 6.49 0.39
43 INT145220 Negative_regulation of Binding of Tp53 1 0.20 0.75 0.36
44 INT93355 Negative_regulation of Negative_regulation of Trp53 2 0.41 0.92 0.3
45 INT179089 Protein_catabolism of Trp53 8 0.90 6.52 0.29
46 INT166960 Positive_regulation of Negative_regulation of TP53 2 0.25 1.65 0.26
47 INT314729 Regulation of Localization of TP53 1 0.30 2.5 0.25
48 INT179088 Positive_regulation of Regulation of Trp53 3 0.38 3.23 0.23
49 INT156886 Positive_regulation of Localization of TP53 1 0.48 0.87 0.23
50 INT300284 Regulation of Phosphorylation of Tp53 1 0.16 1.51 0.17
51 INT337078 Negative_regulation of Localization of Trp53 1 0.20 1.3 0.17
52 INT179086 Positive_regulation of Negative_regulation of Trp53 5 0.50 4.78 0.15
53 INT125081 Positive_regulation of Binding of TP53 2 0.46 1.2 0.15
54 INT207805 Negative_regulation of Phosphorylation of Trp53 2 0.18 0.98 0.15
55 INT286749 Regulation of Localization of Trp53 1 0.06 1.39 0.15
56 INT168244 Regulation of Transcription of Tp53 1 0.33 0.57 0.13
57 INT297456 Protein_catabolism of Tp53 1 0.11 0.72 0.1
58 INT111139 Localization of Tp53 4 0.45 2.4 0.09
59 INT352605 Regulation of Negative_regulation of Trp53 1 0.45 0.72 0.07
60 INT171421 Regulation of Positive_regulation of TP53 1 0.48 0.45 0.05
61 INT315213 Negative_regulation of Binding of Trp53 1 0.32 0.11 0.05
62 INT311668 Regulation of Regulation of TP53 2 0.36 3.58 0.04
63 INT305536 Positive_regulation of Binding of Trp53 1 0.35 0.32 0.04
64 INT217802 Regulation of Transcription of TP53 2 0.37 0.81 0.03
65 INT259061 Negative_regulation of Regulation of TP53 2 0.10 2.23 0.03
66 INT178927 Regulation of Gene_expression of Tp53 6 0.26 2.23 0
67 INT333669 Positive_regulation of Transcription of Trp53 3 0.45 2.33 0
68 INT250698 Positive_regulation of Transcription of TP53 3 0.18 3.68 0
69 INT113348 Negative_regulation of Binding of TP53 2 0.28 1.49 0
70 INT214913 Positive_regulation of Positive_regulation of Tp53 2 0.08 2.47 0
71 INT217820 Regulation of Negative_regulation of TP53 2 0.37 1.92 0
72 INT204059 Positive_regulation of Phosphorylation of Tp53 1 0.07 0.76 0
73 INT333668 Regulation of Protein_catabolism of Trp53 1 0.24 1.58 0
74 INT333671 Regulation of Transcription of Trp53 1 0.24 0.83 0
75 INT179076 Negative_regulation of Protein_catabolism of Trp53 1 0.32 0.43 0
76 INT179957 Positive_regulation of Binding of Tp53 1 0.08 0.48 0
77 INT333663 Positive_regulation of Protein_catabolism of Trp53 1 0.45 0.84 0
78 INT333662 Negative_regulation of Transcription of Trp53 1 0.53 1.15 0
79 INT223765 Negative_regulation of Positive_regulation of Tp53 1 0.07 1.69 0
80 INT305295 Regulation of Binding of TP53 1 0.39 1.09 0
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