GO:0097060

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Name synaptic membrane
Categary Component
Go Slim No
Go Link GO:0097060
Unique Molecular Interactions 284
Total Molecular Interactions 377
Total Single Events 3851
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for synaptic membrane. They are ordered first by their pain relevance and then by number of times they were reported for synaptic membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT130625 Prkcg Regulation of Prkaca 1 0.23 1.32 3.87
2 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
3 INT276676 Prkcg Regulation of Nav1 1 0.30 0.82 3.29
4 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
5 INT276679 Prkcg Positive_regulation of Positive_regulation of Nkx1-1 1 0.07 0.94 3.08
6 INT351349 Prkcg Positive_regulation of Binding of Lpar1 1 0.15 2 2.82
7 INT121742 Prkcg Positive_regulation of Ephb1 3 0.49 0.99 2.6
8 INT144115 Positive_regulation of Grm5 Positive_regulation of Prkcg 1 0.41 0 2.01
9 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
10 INT276669 Negative_regulation of Prkcg Regulation of Nav1 1 0.21 0.68 1.82
11 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
12 INT134363 Prkcg Regulation of ADCY2 1 0.00 0.14 1.7
13 INT276672 Binding of Prkcg and Nav1 1 0.16 0.18 1.67
14 INT276680 Binding of Prkcg and Nkx1-1 1 0.05 0.18 1.66
15 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
16 INT276671 Prkcg Positive_regulation of Nav1 1 0.23 0.21 1.55
17 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
18 INT161870 OPRM1 Positive_regulation of Prkcg 1 0.01 0.12 1.47
19 INT161865 Mors1 Positive_regulation of Prkcg 1 0.00 0.12 1.47
20 INT153581 Binding of Oprm1 and Prkcg 1 0.00 0 1.44
21 INT78974 Binding of Prkcg and Prkaca 2 0.31 0.35 1.4
22 INT131888 gr Positive_regulation of Gene_expression of Prkcg 1 0.00 0 1.32
23 INT120929 Prkcg Regulation of Gene_expression of Fos 2 0.50 0.34 1.31
24 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
25 INT283426 Binding of Lcn2 and Nt5e 1 0.08 5.8 1.24
26 INT298454 Prkcg Positive_regulation of Phosphorylation of Adarb1 1 0.00 0.41 1.19
27 INT85780 Prkaca Regulation of Prkcg 1 0.29 0.47 1.17
28 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
29 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
30 INT130471 Prkcg Regulation of Regulation of Fos 1 0.45 0.27 1.12
31 INT193328 Grid1 Regulation of Positive_regulation of Prkcg 1 0.00 0.1 1.1
32 INT269193 Prkcg Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
33 INT263232 Prkcg Positive_regulation of Trpv4 1 0.12 1.1 1.02
34 INT240453 Prkcg Positive_regulation of Positive_regulation of Prkaca 1 0.23 0.63 1.01
35 INT263227 Positive_regulation of Prkcg Regulation of Trpv4 1 0.07 0.95 1
36 INT78976 Prkcg Regulation of Ina 1 0.13 0.16 0.93
37 INT159996 Prkcg Regulation of Gene_expression of App 1 0.42 0.32 0.92
38 INT159994 App Regulation of Gene_expression of Prkcg 1 0.42 0.32 0.92
39 INT159995 Prkcg Regulation of Gene_expression of Bace1 1 0.39 0.32 0.91
40 INT85783 PRKG1 Regulation of Prkcg 1 0.09 0.38 0.9
41 INT12766 Ins1 Positive_regulation of Prkcg 3 0.53 0.07 0.89
42 INT113383 Negative_regulation of Sert1 Positive_regulation of Prkcg 1 0.31 0 0.89
43 INT152835 Prkcg Regulation of Phosphorylation of Nfasc 1 0.10 0.21 0.87
44 INT152853 Prkcg Regulation of PRS 1 0.01 0.21 0.87
45 INT80792 Prkcg Regulation of Oprd1 1 0.19 0.2 0.86
46 INT80793 Prkcg Regulation of Pkm2 1 0.29 0.2 0.83
47 INT186428 Trib3 Regulation of Prkcg 1 0.02 0.09 0.81
48 INT240456 Ephb1 Regulation of Prkcg 1 0.19 0.51 0.79
49 INT107739 Prkcg Negative_regulation of Positive_regulation of Pld2 1 0.46 0 0.79
50 INT152833 Nefl Regulation of Prkcg 1 0.12 0.19 0.77
51 INT152831 Nefh Regulation of Prkcg 1 0.05 0.19 0.77
52 INT152836 Nefm Regulation of Prkcg 1 0.15 0.19 0.77
53 INT94816 Prkcg Positive_regulation of TACR1 1 0.06 0.1 0.76
54 INT152854 PRS Regulation of Prkcg 1 0.01 0.19 0.76
55 INT219914 Prkcg Regulation of Phosphorylation of Trpv1 1 0.11 1 0.74
56 INT124353 Prkcg Positive_regulation of Positive_regulation of Gorasp2 1 0.02 1.19 0.73
57 INT351351 Prkcg Regulation of Lpar1 1 0.12 0.58 0.72
58 INT263236 DAG1 Positive_regulation of Prkcg 2 0.01 0.31 0.7
59 INT186162 Phosphorylation of Prkaca Positive_regulation of Phosphorylation of Prkcg 1 0.04 0.22 0.7
60 INT171825 Binding of Prkcg and Ncs1 1 0.00 0.07 0.66
61 INT330046 Mapk8 Negative_regulation of Prkcg 1 0.13 0.4 0.66
62 INT265144 Olah Positive_regulation of Prkcg 1 0.02 0 0.62
63 INT265140 Olah Regulation of Prkcg 1 0.01 0 0.62
64 INT131072 Cc2d1b Negative_regulation of Prkcg 1 0.01 0 0.58
65 INT270943 Binding of Prkcg and Cpe 1 0.05 0 0.58
66 INT263230 Prkcg Regulation of Trpv1 1 0.05 0.95 0.56
67 INT78973 Prkcg Positive_regulation of Positive_regulation of Ina 1 0.10 0.07 0.55
68 INT263231 Positive_regulation of Trpv1 Positive_regulation of Prkcg 1 0.08 0.57 0.55
69 INT311256 Nt5e Positive_regulation of Positive_regulation of Adora1 1 0.49 0.19 0.54
70 INT263229 Trpv1 Positive_regulation of Prkcg 1 0.08 0.57 0.54
71 INT97425 Prkcg Regulation of Regulation of Nos1 1 0.06 0 0.53
72 INT330544 Bcl2l11 Negative_regulation of Prkcg 1 0.03 0.38 0.52
73 INT330541 Bcl2l11 Negative_regulation of Negative_regulation of Prkcg 1 0.03 0.38 0.52
74 INT144130 Binding of Gja1 and Prkcg 1 0.48 0.5 0.52
75 INT160203 Prkcc Positive_regulation of Src 1 0.02 0 0.51
76 INT263228 Prkcg Regulation of Trpv4 1 0.07 0.36 0.5
77 INT153580 Binding of Prkcc and Hint1 1 0.03 0 0.49
78 INT114543 Bdnf Positive_regulation of Prkcg 1 0.21 0 0.49
79 INT330543 Prkcg Regulation of Regulation of Trpm8 1 0.11 0.28 0.47
80 INT322131 Binding of Prkcg and Trpv4 1 0.04 0.75 0.46
81 INT91087 SST Positive_regulation of Positive_regulation of Prkcg 1 0.29 0.05 0.43
82 INT74548 Prkcg Regulation of Tecr 1 0.48 0 0.43
83 INT15024 Prkcg Regulation of Pdpk1 1 0.09 0 0.43
84 INT69851 Prkcg Regulation of Pigm 1 0.16 0 0.41
85 INT157650 Phosphorylation of Prkcc Positive_regulation of Pik3c3 1 0.51 0 0.41
86 INT157646 Positive_regulation of Oprd1 Positive_regulation of Phosphorylation of Prkcc 1 0.01 0 0.4
87 INT157649 Prkcc Regulation of Pik3c3 1 0.30 0 0.39
88 INT153052 Prkcg Positive_regulation of Phosphorylation of Trpv1 1 0.45 0 0.38
89 INT12767 Ins1 Positive_regulation of Phosphorylation of Prkcg 1 0.36 0 0.38
90 INT201485 Ntrk2 Positive_regulation of Prkcg 1 0.01 0.73 0.38
91 INT171823 Nrgn Positive_regulation of Prkcg 1 0.18 0.53 0.36
92 INT85779 Rb1 Regulation of Prkcg 1 0.01 0.38 0.36
93 INT157648 Binding of Prkcc and Pik3c3 1 0.39 0 0.36
94 INT263226 Prkcg Negative_regulation of Positive_regulation of Ca2 1 0.01 0.58 0.36
95 INT270936 Prkcg Regulation of Flvcr2 1 0.00 0 0.35
96 INT265146 Calm2 Negative_regulation of Phosphorylation of Prkcg 1 0.04 0.07 0.35
97 INT238261 pma Positive_regulation of Prkcg 1 0.01 0.33 0.34
98 INT265142 Prkcg Regulation of Localization of Chrm1 1 0.04 0 0.34
99 INT280808 Prkcg Positive_regulation of Transcription of Fos 1 0.02 0.06 0.33
100 INT322129 Binding of Prkcg and Ca2 1 0.00 0.57 0.33
101 INT265147 Prkcg Regulation of Gene_expression of Chrm1 1 0.04 0 0.33
102 INT201484 Negative_regulation of Prkcg Negative_regulation of Positive_regulation of Ednrb 1 0.34 0.96 0.32
103 INT126851 Prkcg Positive_regulation of Creb1 1 0.46 0.09 0.32
104 INT52700 Prkcg Positive_regulation of Ptgs2 1 0.12 0.3 0.32
105 INT66414 Prkcg Regulation of Penk 1 0.17 0 0.32
106 INT66413 Prkcg Regulation of Positive_regulation of Penk 1 0.38 0 0.32
107 INT69854 Prkcg Regulation of Transcription of Pdyn 1 0.00 0 0.28
108 INT69853 Prkcg Regulation of Pdyn 1 0.00 0 0.28
109 INT69852 Prkcg Regulation of Pdyn 1 0.14 0 0.28
110 INT280807 Mapk1 Positive_regulation of Positive_regulation of Prkcg 1 0.01 0.08 0.28
111 INT280805 Positive_regulation of Prkcg Positive_regulation of Avp 1 0.01 0.16 0.26
112 INT149947 Ephb1 Positive_regulation of Prkcg 1 0.27 0.07 0.26
113 INT237749 Prkcg Regulation of Transcription of Pcgf1 1 0.14 0.68 0.25
114 INT71429 Calca Positive_regulation of Prkcg 1 0.54 0 0.21
115 INT126046 Binding of Prkcg and Emp1 1 0.33 0.25 0.21
116 INT283429 Nt5e Regulation of Gene_expression of Cxcr1 1 0.00 0.22 0.2
117 INT238262 Prkcg Negative_regulation of Gene_expression of Cr1l 1 0.12 0.26 0.16
118 INT283428 Negative_regulation of Binding of Lcn2 and Nt5e 1 0.06 1.09 0.15
119 INT219912 Trpv1 Regulation of Prkcg 1 0.11 0 0.15
120 INT311255 Binding of Gpi1 and Nt5e 1 0.05 0.16 0.13
121 INT326246 Prkcg Positive_regulation of ras 1 0.01 0.62 0.13
122 INT353897 Negative_regulation of Prkcg Negative_regulation of Localization of Bcl2l11 1 0.08 0.4 0.13
123 INT326249 Prkcg Positive_regulation of EPHB2 1 0.06 0.63 0.13
124 INT326247 Prkcg Positive_regulation of Prkaca 1 0.00 0.62 0.13
125 INT237746 Prkcg Regulation of Pcgf1 1 0.14 0.34 0.12
126 INT270957 Prkcg Negative_regulation of Flvcr2 1 0.00 0 0.1
127 INT283427 Lcn2 Positive_regulation of Nt5e 1 0.08 0.21 0.09
128 INT171400 Binding of Adcyap1 and Prkcg 1 0.01 0.24 0.08
129 INT77938 Prkcg Positive_regulation of Localization of Gnrh1 1 0.32 0 0.08
130 INT283425 Lcn2 Positive_regulation of Gene_expression of Nt5e 1 0.07 0.13 0.07
131 INT283433 Nt5e Positive_regulation of Localization of IL8 1 0.01 0.21 0.07
132 INT275102 Prkcg Regulation of CREB1 1 0.01 0 0.06
133 INT275101 CAMK4 Positive_regulation of Prkcg 1 0.01 0 0.06
134 INT275103 CA2 Positive_regulation of Prkcg 1 0.01 0 0.06
135 INT275105 CALM3 Positive_regulation of Prkcg 1 0.00 0 0.06
136 INT307454 Prkcg Regulation of Phosphorylation of Gsk3a 1 0.04 0.13 0.05
137 INT326250 Prkcg Positive_regulation of ARAF 1 0.00 0 0.05
138 INT171399 Binding of Npr1 and Prkcg 1 0.00 0.23 0.04
139 INT191214 Cotl1 Positive_regulation of Prkcg 1 0.10 1.35 0.04
140 INT290904 Shh Positive_regulation of Prkcg 1 0.26 0.06 0
141 INT290900 Prkcg Regulation of Shh 1 0.23 0 0
142 INT87159 Phosphorylation of Marcks Positive_regulation of Prkcg 1 0.07 0 0
143 INT87160 Prkcg Regulation of Pmf1 1 0.39 0 0
144 INT191218 Edn1 Regulation of Positive_regulation of Prkcg 1 0.14 0.32 0
145 INT330049 Prkcg Negative_regulation of Pnck 1 0.01 0.28 0
146 INT143144 Prkcg Negative_regulation of Gene_expression of Acta2 1 0.00 0.15 0
147 INT228285 Binding of Ptprc and Nt5e 1 0.06 0.25 0
148 INT290899 Prkcg Regulation of Positive_regulation of Nos2 1 0.14 0 0
149 INT228286 Binding of Cd14 and Nt5e 1 0.20 0.25 0
150 INT290902 Prkcg Regulation of Positive_regulation of Ntn1 1 0.10 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for synaptic membrane. They are ordered first by their pain relevance and then by number of times they were reported in synaptic membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41
2 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47
3 INT47243 Gene_expression of Prkcg 195 0.78 58.05 108.44
4 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63
5 INT12536 Localization of Prkcg 101 0.80 36.37 73.81
6 INT39777 Regulation of Prkcg 90 0.62 31.52 68.17
7 INT48959 Positive_regulation of Positive_regulation of Prkcg 52 0.70 16.47 36.49
8 INT12765 Positive_regulation of Phosphorylation of Prkcg 59 0.66 20.16 34.67
9 INT12537 Positive_regulation of Localization of Prkcg 36 0.70 14.57 33.81
10 INT51698 Positive_regulation of Gene_expression of Prkcg 44 0.68 14.02 32.9
11 INT9133 Negative_regulation of Positive_regulation of Prkcg 37 0.59 10.95 30.06
12 INT87607 Positive_regulation of Prkcc 25 0.69 6.06 22.78
13 INT65211 Binding of Prkcg 38 0.48 14.75 16.92
14 INT74545 Negative_regulation of Gene_expression of Prkcg 22 0.42 7.77 16.26
15 INT9525 Regulation of Positive_regulation of Prkcg 20 0.62 7.82 16.18
16 INT79887 Gene_expression of Prkcc 20 0.78 12.59 14.73
17 INT63854 Regulation of Gene_expression of Prkcg 27 0.56 9.41 14.15
18 INT47847 Negative_regulation of Localization of Prkcg 11 0.58 4.02 12.36
19 INT79248 Regulation of Negative_regulation of Prkcg 13 0.44 3.44 9.78
20 INT47845 Regulation of Localization of Prkcg 16 0.62 3.1 9.42
21 INT71565 Negative_regulation of Prkcc 11 0.54 4.16 9.31
22 INT79247 Negative_regulation of Negative_regulation of Prkcg 11 0.42 1.78 7.13
23 INT115849 Localization of Prkcc 5 0.77 0.65 6.26
24 INT127237 Phosphorylation of Prkcc 7 0.81 0 5.96
25 INT59879 Transcription of Prkcg 9 0.69 2.29 5.3
26 INT19391 Gene_expression of Nt5e 44 0.72 13.99 5.14
27 INT148168 Positive_regulation of Localization of Prkcc 4 0.48 0.15 4.03
28 INT65210 Positive_regulation of Binding of Prkcg 6 0.70 2.71 3.65
29 INT74374 Negative_regulation of Phosphorylation of Prkcg 7 0.41 1.28 3.57
30 INT129752 Regulation of Phosphorylation of Prkcg 8 0.31 1.43 3.41
31 INT161863 Positive_regulation of Regulation of Prkcg 4 0.27 1.63 3.1
32 INT130616 Positive_regulation of Negative_regulation of Prkcg 5 0.48 1.6 3.08
33 INT181668 Protein_catabolism of Prkcg 8 0.77 2.59 3.06
34 INT94687 Binding of Prkcc 5 0.37 0.34 3.02
35 INT95779 Positive_regulation of Gene_expression of Prkcc 5 0.69 5.66 3.02
36 INT59878 Negative_regulation of Transcription of Prkcg 3 0.43 2.15 2.85
37 INT59877 Regulation of Regulation of Prkcg 2 0.45 1.17 2.81
38 INT89026 Positive_regulation of Nt5e 12 0.49 7.25 2.67
39 INT148166 Positive_regulation of Phosphorylation of Prkcc 2 0.68 0 2.44
40 INT70174 Negative_regulation of Regulation of Prkcg 3 0.42 0.88 1.98
41 INT135332 Positive_regulation of Negative_regulation of Prkcc 1 0.46 0.74 1.75
42 INT222031 Localization of Nt5e 16 0.75 3.1 1.73
43 INT241733 Negative_regulation of Nt5e 4 0.40 2.84 1.58
44 INT121297 Positive_regulation of Positive_regulation of Prkcc 1 0.50 0 1.38
45 INT183568 Negative_regulation of Protein_catabolism of Prkcg 2 0.36 1.12 1.33
46 INT154041 Negative_regulation of Localization of Prkcc 1 0.42 0.3 1.1
47 INT153563 Negative_regulation of Phosphorylation of Prkcc 2 0.42 0 1.04
48 INT182594 Regulation of Protein_catabolism of Prkcg 1 0.39 0 0.88
49 INT283402 Binding of Nt5e 10 0.30 2.53 0.85
50 INT265156 Regulation of Binding of Prkcg 1 0.15 0.18 0.78
51 INT87606 Regulation of Prkcc 2 0.43 1.05 0.72
52 INT121296 Negative_regulation of Positive_regulation of Prkcc 1 0.58 0 0.72
53 INT280801 Positive_regulation of Transcription of Prkcg 1 0.07 0.12 0.67
54 INT247550 Positive_regulation of Gene_expression of Nt5e 5 0.56 3.21 0.61
55 INT156528 Negative_regulation of Gene_expression of Prkcc 1 0.36 1.91 0.59
56 INT87608 Positive_regulation of Regulation of Prkcc 1 0.45 0.9 0.49
57 INT283403 Phosphorylation of Nt5e 2 0.67 0.23 0.21
58 INT283404 Positive_regulation of Phosphorylation of Nt5e 1 0.07 0.23 0.21
59 INT181674 Positive_regulation of Protein_catabolism of Prkcg 1 0.14 0.37 0.21
60 INT247566 Transcription of Nt5e 3 0.17 1.73 0.19
61 INT247554 Negative_regulation of Negative_regulation of Nt5e 1 0.10 1.85 0.08
62 INT247552 Regulation of Nt5e 1 0.05 2.07 0.07
63 INT283401 Positive_regulation of Binding of Nt5e 1 0.06 0.41 0.04
64 INT172322 Negative_regulation of Gene_expression of Nt5e 1 0.41 1.03 0.04
65 INT283409 Positive_regulation of Transcription of Nt5e 1 0.07 0.06 0.03
66 INT283405 Positive_regulation of Localization of Nt5e 1 0.07 0 0
67 INT183569 Negative_regulation of Binding of Prkcg 1 0.05 0.69 0
68 INT311251 Protein_catabolism of Nt5e 1 0.53 0 0
69 INT283398 Negative_regulation of Binding of Nt5e 1 0.05 0.46 0
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