GO:0097067

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Name cellular response to thyroid hormone stimulus
Categary Process
Go Slim No
Go Link GO:0097067
Unique Molecular Interactions 49
Total Molecular Interactions 73
Total Single Events 345
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular response to thyroid hormone stimulus. They are ordered first by their pain relevance and then by number of times they were reported for cellular response to thyroid hormone stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7190 Syt17 Positive_regulation of Ctsb 1 0.16 0 3.23
2 INT7193 Abl2 Positive_regulation of Ctsb 1 0.21 0 3.21
3 INT7195 Negative_regulation of Syt17 Positive_regulation of Ctsb 1 0.10 0 2.25
4 INT7186 Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
5 INT7184 Negative_regulation of Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
6 INT7191 Negative_regulation of Abl2 Positive_regulation of Ctsb 1 0.13 0 1.04
7 INT335644 CTSB Positive_regulation of F2RL1 1 0.02 2.58 0.82
8 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62
9 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62
10 INT36320 PDYN Negative_regulation of Ctsb 1 0.00 0 0.61
11 INT118485 CST3 Regulation of CTSH 1 0.36 0 0.49
12 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
13 INT139873 Negative_regulation of CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
14 INT335643 CTSB Positive_regulation of PAR4 1 0.01 1.3 0.41
15 INT139874 CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
16 INT28688 Binding of Kng1 and Ctsl1 1 0.15 0 0.31
17 INT135095 Negative_regulation of CTSB Negative_regulation of APP 1 0.00 0.74 0.3
18 INT50107 Ei24 Positive_regulation of Localization of CTSB 3 0.00 0.6 0.29
19 INT258858 CTSB Positive_regulation of Gene_expression of IL8 1 0.00 0.64 0.28
20 INT139980 Negative_regulation of CTSB Negative_regulation of Gene_expression of APP 1 0.15 0.7 0.26
21 INT139981 CTSB Negative_regulation of Gene_expression of APP 1 0.11 0.7 0.26
22 INT118418 Gata1 Positive_regulation of Transcription of Tac2 1 0.61 0.77 0.25
23 INT118419 Binding of Gata1 and Tac2 1 0.31 0.7 0.24
24 INT159132 Klf9 Positive_regulation of Smc5 1 0.01 0.48 0.2
25 INT245183 Binding of CTSB and TCF7L2 1 0.39 6.39 0.18
26 INT190635 Binding of Lmo2 and Nr1h2 1 0.09 0.59 0.16
27 INT190629 Binding of Lmo2 and Usf1 1 0.11 0.6 0.16
28 INT190634 Binding of Lmo2 and Maz 1 0.14 0.59 0.16
29 INT190633 Binding of Lmo2 and Deaf1 1 0.18 0.59 0.16
30 INT156833 Binding of MED1 and TRPV6 1 0.32 0 0.15
31 INT156837 Binding of CYP24A1 and MED1 1 0.47 0 0.15
32 INT171645 Negative_regulation of CTSB Positive_regulation of PRSS1 1 0.44 0.36 0.1
33 INT171644 CTSB Positive_regulation of PRSS1 1 0.52 0.36 0.1
34 INT171648 Binding of CTSB and PRSS1 1 0.27 0.42 0.1
35 INT118417 Gata1 Regulation of Gene_expression of Serpinb9g 1 0.17 0.12 0.06
36 INT225490 Med1 Positive_regulation of Ppara 1 0.12 0.26 0.06
37 INT62030 Bche Regulation of Localization of CTSB 1 0.09 0.15 0.06
38 INT261393 Binding of Nsdhl and Med1 1 0.02 1 0.04
39 INT110967 REG1A Positive_regulation of Gene_expression of CTSB 1 0.01 0 0.04
40 INT354622 CTSB Regulation of PRDX5 1 0.00 0.38 0
41 INT225585 Regulation of Binding of Med1 and Tpr 1 0.00 0.07 0
42 INT129874 Binding of CST3 and CTSS 1 0.42 2.45 0
43 INT177262 Binding of MED1 and SV2A 1 0.23 0 0
44 INT225481 Binding of Med1 and Acp5 1 0.16 0 0
45 INT177286 Binding of CXADR and MED1 1 0.27 0 0
46 INT304168 Binding of Gata1 and Sfpi1 1 0.08 0.07 0
47 INT171647 CTSB Positive_regulation of NXF1 1 0.23 0.47 0
48 INT225541 Binding of Med1 and Tpr 1 0.00 0.07 0
49 INT177280 Binding of MED1 and FAUP1 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular response to thyroid hormone stimulus. They are ordered first by their pain relevance and then by number of times they were reported in cellular response to thyroid hormone stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT3623 Negative_regulation of CTSB 49 0.55 27.39 13.52
2 INT3622 Regulation of CTSB 34 0.58 16.08 8.76
3 INT7168 Positive_regulation of Ctsb 9 0.70 0.3 7.58
4 INT50105 Localization of CTSB 29 0.78 10.98 5.21
5 INT7170 Positive_regulation of Positive_regulation of Ctsb 1 0.40 0 4.76
6 INT20265 Gene_expression of Ctsb 3 0.47 1.01 3.52
7 INT110980 Gene_expression of CTSB 17 0.45 8.02 2.69
8 INT73028 Positive_regulation of Transcription of Ctsb 1 0.55 1.53 2.54
9 INT59135 Positive_regulation of CTSB 15 0.67 7.53 2.53
10 INT37427 Positive_regulation of Gene_expression of Ctsb 2 0.37 1.02 2.33
11 INT7173 Regulation of Positive_regulation of Ctsb 1 0.49 0 2.29
12 INT50106 Positive_regulation of Localization of CTSB 9 0.33 3.15 1.69
13 INT73027 Transcription of Ctsb 1 0.56 1.01 1.68
14 INT118412 Gene_expression of Gata1 5 0.62 0.83 1.6
15 INT118413 Positive_regulation of Gene_expression of Gata1 3 0.40 0.68 1.56
16 INT42335 Binding of CTSB 11 0.34 5.98 1.37
17 INT20317 Localization of Ctsb 3 0.81 0.68 1.12
18 INT59136 Negative_regulation of Positive_regulation of CTSB 3 0.41 2.02 1.11
19 INT129878 Positive_regulation of CTSS 6 0.70 7.86 0.97
20 INT6534 Negative_regulation of Ctsl1 3 0.54 0.11 0.94
21 INT7175 Negative_regulation of Positive_regulation of Ctsb 1 0.34 0 0.86
22 INT129877 Gene_expression of CTSS 4 0.75 4.65 0.81
23 INT79243 Negative_regulation of Localization of CTSB 2 0.57 1.35 0.73
24 INT144995 Positive_regulation of Gata1 1 0.37 0.14 0.71
25 INT129879 Positive_regulation of Gene_expression of CTSS 3 0.47 3.25 0.7
26 INT20318 Regulation of Ctsb 1 0.54 0.19 0.69
27 INT59137 Protein_catabolism of CTSB 5 0.96 3.92 0.62
28 INT28687 Gene_expression of Ctsl1 4 0.61 0.48 0.57
29 INT51843 Localization of Ctsl1 3 0.62 0.54 0.54
30 INT126367 Positive_regulation of Gene_expression of CTSB 3 0.04 1.57 0.52
31 INT193736 Regulation of Positive_regulation of CTSB 1 0.04 1.13 0.52
32 INT36603 Positive_regulation of CTSH 1 0.01 0 0.46
33 INT6533 Binding of Ctsl1 2 0.34 0 0.45
34 INT335648 Localization of CTSS 1 0.08 1.39 0.41
35 INT348083 Positive_regulation of Ctsl1 1 0.08 0.21 0.4
36 INT145045 Gene_expression of Med1 29 0.65 5.37 0.39
37 INT233917 Gene_expression of MED1 2 0.20 0.17 0.38
38 INT6536 Negative_regulation of Binding of Ctsl1 1 0.39 0 0.3
39 INT106734 Phosphorylation of MED1 4 0.74 1.65 0.28
40 INT126366 Regulation of Binding of CTSB 1 0.01 0.31 0.28
41 INT36060 Protein_catabolism of Ctsl1 2 0.83 0.15 0.22
42 INT124178 Regulation of Ctsl1 1 0.23 0.19 0.22
43 INT129875 Positive_regulation of Positive_regulation of CTSS 1 0.50 1.94 0.2
44 INT45092 Positive_regulation of Localization of Ctsb 1 0.50 0 0.19
45 INT142708 Gene_expression of CTSH 1 0.75 1.51 0.18
46 INT190551 Localization of Lmo2 1 0.21 0.6 0.17
47 INT129876 Negative_regulation of Positive_regulation of CTSS 1 0.43 1.88 0.17
48 INT106730 Regulation of Phosphorylation of MED1 2 0.24 0.7 0.16
49 INT220570 Transcription of Gata1 2 0.05 0.91 0.14
50 INT348081 Positive_regulation of Gene_expression of Ctsl1 1 0.06 0.24 0.14
51 INT106731 Negative_regulation of Phosphorylation of MED1 1 0.02 0.96 0.12
52 INT190566 Gene_expression of Lmo2 1 0.43 0.9 0.12
53 INT36061 Negative_regulation of Protein_catabolism of Ctsl1 1 0.12 0.08 0.1
54 INT62029 Regulation of Localization of CTSB 2 0.05 0.21 0.09
55 INT156864 Positive_regulation of Phosphorylation of MED1 1 0.45 0 0.07
56 INT55785 Negative_regulation of Localization of Ctsb 1 0.23 0.51 0.07
57 INT180694 Regulation of Localization of Ctsl1 1 0.16 0 0.05
58 INT307189 Localization of Med1 3 0.53 0.32 0
59 INT225400 Positive_regulation of Gene_expression of Med1 2 0.35 0.82 0
60 INT225358 Negative_regulation of Gene_expression of Med1 2 0.30 1.16 0
61 INT177336 Positive_regulation of Binding of MED1 1 0.24 0 0
62 INT307197 Negative_regulation of Med1 1 0.30 0.7 0
63 INT307188 Transcription of Med1 1 0.48 0.7 0
64 INT175639 Binding of CTSS 1 0.36 1.44 0
65 INT225389 Regulation of Binding of Med1 1 0.17 0.07 0
66 INT177320 Binding of MED1 1 0.25 0 0
67 INT171654 Regulation of Regulation of CTSB 1 0.18 0.18 0
68 INT225457 Binding of Med1 1 0.35 0.28 0
69 INT341851 Positive_regulation of MED1 1 0.01 0.5 0
70 INT334482 Regulation of Gene_expression of Med1 1 0.17 0.1 0
71 INT262679 Phosphorylation of Gata1 1 0.18 0.55 0
72 INT262696 Binding of Gata1 1 0.08 0.56 0
73 INT334481 Negative_regulation of Localization of Med1 1 0.16 0.09 0
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