GO:0097110

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Name scaffold protein binding
Categary Function
Go Slim No
Go Link GO:0097110
Unique Molecular Interactions 208
Total Molecular Interactions 308
Total Single Events 1962
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for scaffold protein binding. They are ordered first by their pain relevance and then by number of times they were reported for scaffold protein binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT296275 Binding of Dlg4 and Kcnip3 1 0.39 3.58 5.6
2 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
3 INT296280 Binding of Car2 and Dlg4 1 0.19 0.45 1.71
4 INT73597 Positive_regulation of BAX Positive_regulation of Casp1 1 0.06 0.69 1.28
5 INT73598 BAX Positive_regulation of Casp1 1 0.06 0.63 1.27
6 INT251142 Binding of Dlg4 and Grin2a 3 0.30 0.5 1.24
7 INT156380 Regulation of Binding of Grin1 and Dlg4 1 0.29 0.32 0.97
8 INT145853 Casp1 Positive_regulation of Mapk14 1 0.02 0.68 0.93
9 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
10 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
11 INT120820 Binding of ASIC3 and Dlg4 3 0.02 0.11 0.84
12 INT339293 Casp1 Regulation of Localization of Il1 1 0.07 1.87 0.83
13 INT155760 Binding of Nos1 and Dlg4 1 0.13 1.01 0.82
14 INT339291 Casp1 Positive_regulation of Il1 2 0.12 1.63 0.8
15 INT152947 Dlg4 Regulation of Sgk1 1 0.09 0.18 0.76
16 INT152945 Dlg4 Regulation of Cap1 1 0.11 0.18 0.76
17 INT152949 Homer1 Regulation of Sgk1 1 0.28 0.18 0.76
18 INT152946 Homer1 Regulation of Cap1 1 0.32 0.18 0.76
19 INT152948 Homer1 Regulation of Gpr88 1 0.36 0.18 0.75
20 INT152944 Dlg4 Regulation of Gpr88 1 0.12 0.18 0.75
21 INT205706 P2rx7 Regulation of Gene_expression of Il18 1 0.21 1.35 0.7
22 INT246335 Fig4 Regulation of Localization of P2rx7 1 0.01 0 0.67
23 INT205702 P2rx7 Regulation of Gene_expression of Il1 1 0.04 1.38 0.67
24 INT168205 Binding of Dlg4 and Pik3cd 1 0.11 0.37 0.65
25 INT70161 Casp1 Regulation of Oprd1 1 0.03 0 0.65
26 INT70162 Casp1 Regulation of Penk 1 0.03 0 0.64
27 INT128811 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Casp1 1 0.06 0.35 0.61
28 INT66766 Casp1 Positive_regulation of Transcription of Pla2g10 1 0.06 0.19 0.6
29 INT128604 Casp1 Positive_regulation of Gene_expression of Fos 1 0.10 0.55 0.59
30 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 0.07 1.42 0.58
31 INT308174 Binding of TNF and P2rx7 1 0.02 0.84 0.56
32 INT339290 Casp1 Regulation of Gene_expression of Il1 1 0.11 1.38 0.55
33 INT251141 Binding of Dlg4 and Grin2b 1 0.14 0.32 0.55
34 INT297311 Casp1 Positive_regulation of Il18 1 0.09 1.02 0.55
35 INT185490 Atp5o Negative_regulation of Gene_expression of P2rx7 1 0.01 0.87 0.53
36 INT216941 P2rx7 Regulation of Ryr1 1 0.01 0.55 0.52
37 INT278122 Negative_regulation of P2rx7 Negative_regulation of Binding of P2RX7 1 0.03 0 0.51
38 INT81064 Negative_regulation of Nts Negative_regulation of Gene_expression of Homer1 1 0.01 0 0.48
39 INT263746 Binding of Dlg4 and Neto1 1 0.27 0 0.48
40 INT222284 Negative_regulation of Casp1 Negative_regulation of Il18 1 0.01 0.79 0.46
41 INT222283 Negative_regulation of Casp1 Negative_regulation of Il1a 1 0.00 0.78 0.46
42 INT198931 Binding of Dlg4 and Lrp8 1 0.06 0.23 0.46
43 INT90079 Ass1 Positive_regulation of Casp1 1 0.02 0.99 0.43
44 INT169859 P2rx7 Regulation of Gene_expression of Grin1 1 0.17 0 0.43
45 INT296477 Binding of Cacng2 and Dlg4 1 0.04 0.22 0.42
46 INT135426 Binding of APBB1 and Dlg4 1 0.00 0.17 0.42
47 INT283714 Positive_regulation of Binding of Id2 and Homer1 1 0.08 1.34 0.42
48 INT283713 Binding of Id2 and Homer1 1 0.06 1.34 0.42
49 INT278389 Binding of Casp1 and Il1 2 0.09 0.82 0.36
50 INT120821 Dlg4 Positive_regulation of ASIC3 1 0.02 0 0.36
51 INT205704 P2rx7 Regulation of Localization of Il18 1 0.09 0.67 0.35
52 INT272602 Binding of Dlg4 and Gria2 3 0.09 0.19 0.34
53 INT120817 Binding of Dlg4 and Lin7b 1 0.00 0 0.34
54 INT296465 Binding of Dlg4 and Rbm39 1 0.00 0.05 0.34
55 INT205713 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of IL8 1 0.03 0.77 0.33
56 INT217025 P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
57 INT217024 Regulation of P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
58 INT205703 P2rx7 Regulation of Positive_regulation of Casp1 1 0.11 0.66 0.33
59 INT283841 Dlg4 Negative_regulation of Insrr 1 0.01 0.95 0.33
60 INT205711 P2rx7 Regulation of Localization of IL8 1 0.02 0.92 0.33
61 INT198779 Binding of Dlg4 and Psd 10 0.25 0.09 0.31
62 INT145682 Binding of P2rx4 and P2rx7 2 0.25 0.36 0.31
63 INT215789 Fig4 Positive_regulation of Localization of P2rx7 1 0.03 0.53 0.29
64 INT135425 Binding of Dlg4 and Dlg3 1 0.29 0.07 0.28
65 INT274944 Binding of Dlg4 and Pick1 1 0.04 0 0.28
66 INT274939 Binding of Dlg4 and Ephb6 1 0.12 0 0.25
67 INT205701 P2rx7 Positive_regulation of Il1 1 0.04 0.8 0.25
68 INT185489 Atp5o Negative_regulation of P2rx7 1 0.01 0.29 0.24
69 INT191687 Igh-Dex Positive_regulation of Gene_expression of Xiap 1 0.01 0.63 0.24
70 INT191689 Igh-Dex Positive_regulation of Xiap 1 0.01 0.63 0.24
71 INT263787 Binding of GRIN1 and Dlg4 3 0.18 0.05 0.23
72 INT198776 Binding of Dlg4 and Psds1 1 0.11 0.05 0.23
73 INT216911 Positive_regulation of P2rx7 Positive_regulation of Localization of Plg 1 0.02 0.13 0.23
74 INT69042 Negative_regulation of Casp1 Negative_regulation of Positive_regulation of IL1B 1 0.21 0.17 0.22
75 INT69041 Casp1 Negative_regulation of Gene_expression of IL1B 1 0.21 0.17 0.22
76 INT150582 Creb1 Positive_regulation of Gene_expression of Homer1 1 0.00 0 0.22
77 INT69040 Casp1 Negative_regulation of Gene_expression of IFNA1 1 0.07 0.17 0.22
78 INT69039 Negative_regulation of Casp1 Negative_regulation of Gene_expression of IFNA1 1 0.07 0.17 0.22
79 INT107219 Binding of P2rx7 and Atp5o 1 0.03 0.07 0.21
80 INT174679 Homer1 Regulation of Luc7l3 1 0.02 0.67 0.21
81 INT216946 P2rx7 Regulation of Il10 1 0.28 0.17 0.21
82 INT107223 APEH Negative_regulation of P2rx7 1 0.00 0.13 0.21
83 INT205710 CAMP Positive_regulation of P2rx7 1 0.02 0.47 0.19
84 INT273099 Bdnf Positive_regulation of Localization of Dlg4 1 0.21 0.07 0.18
85 INT69038 Casp1 Regulation of Gene_expression of IFNA1 1 0.07 0.16 0.18
86 INT261518 Binding of DLG4 and HTR4 1 0.01 0 0.16
87 INT58179 Gtf3a Positive_regulation of Gene_expression of Homer1 1 0.07 0.1 0.16
88 INT218930 Akt1 Positive_regulation of Xiap 1 0.06 0.64 0.16
89 INT354968 Shank3 Positive_regulation of Gene_expression of Gria2 1 0.05 0 0.15
90 INT261520 Binding of DLG4 and HTR2A 1 0.06 0 0.14
91 INT272605 Binding of Dlg4 and Nsf 1 0.36 0.41 0.14
92 INT270827 P2rx7 Positive_regulation of Localization of Panx1 1 0.41 0.18 0.13
93 INT354705 Binding of ASIC2 and Dlg4 1 0.00 0.11 0.12
94 INT265982 Homer1 Regulation of Grm5 1 0.04 0.38 0.12
95 INT216945 Positive_regulation of P2rx7 Positive_regulation of Positive_regulation of Casp1 1 0.14 0.18 0.12
96 INT354698 Binding of Dlg4 and Gopc 1 0.02 0.11 0.12
97 INT74504 Binding of P2rx7 and Rp2 1 0.02 0.19 0.11
98 INT354717 Binding of ASIC1 and Dlg4 1 0.02 0 0.11
99 INT205709 CAMP Positive_regulation of Positive_regulation of Casp1 1 0.00 0.27 0.11
100 INT303179 Binding of Dlgap1 and Shank1 1 0.22 0.31 0.1
101 INT270834 CBX1 Negative_regulation of Transcription of Panx1 1 0.06 0.13 0.1
102 INT270837 Negative_regulation of Panx1 Negative_regulation of Transcription of CBX1 1 0.07 0.13 0.1
103 INT101880 Oxt Positive_regulation of Gene_expression of Homer1 1 0.23 0.14 0.1
104 INT205708 Binding of Icam1 and P2rx7 1 0.08 1.03 0.09
105 INT272265 Binding of Dlg4 and Grip2 1 0.02 0 0.09
106 INT270833 Binding of CASP1 and Panx1 1 0.02 0.14 0.09
107 INT217036 IRF6 Positive_regulation of Gene_expression of P2rx7 1 0.02 0 0.09
108 INT270824 Binding of P2rx7 and Panx1 1 0.34 0.15 0.09
109 INT270830 Panx1 Negative_regulation of CASP1 1 0.03 0.09 0.09
110 INT265981 Homer1 Regulation of Localization of Grm5 1 0.04 0.06 0.09
111 INT304464 Binding of P2rx7 and P2rx6 1 0.05 0 0.09
112 INT303180 Trim3 Negative_regulation of Shank1 1 0.40 0 0.09
113 INT354962 Gene_expression of Shank3 Positive_regulation of Gusb 1 0.10 0.45 0.08
114 INT270832 Negative_regulation of Panx1 Negative_regulation of Gene_expression of CASP1 1 0.03 0.14 0.08
115 INT243156 Positive_regulation of P2rx7 Positive_regulation of NOS1 1 0.00 0.08 0.08
116 INT270829 P2rx7 Positive_regulation of Panx1 1 0.66 0.08 0.08
117 INT340420 Hmmr Regulation of P2rx7 1 0.01 1.12 0.08
118 INT278376 Negative_regulation of Casp1 Negative_regulation of Hps5 1 0.05 0.05 0.08
119 INT263764 Dlg4 Regulation of Localization of Grin2a 1 0.16 0.17 0.07
120 INT263741 Grin2b Regulation of Localization of Dlg4 1 0.17 0.17 0.07
121 INT263784 Dlg4 Regulation of Localization of Grin1 1 0.17 0.17 0.07
122 INT272595 Binding of Dlg4 and Dnahc8 1 0.03 0.21 0.07
123 INT265983 Homer1 Regulation of Ryr1 1 0.37 0.15 0.07
124 INT263734 Dlg4 Regulation of Localization of Vamp2 1 0.15 0.17 0.07
125 INT270835 Positive_regulation of P2rx7 Positive_regulation of Localization of DPEP1 1 0.04 0.08 0.07
126 INT263742 Grin1 Regulation of Localization of Dlg4 1 0.19 0.17 0.07
127 INT303176 Gene_expression of Trim3 Positive_regulation of Protein_catabolism of Shank1 1 0.44 0 0.07
128 INT263771 Grin2a Regulation of Localization of Dlg4 1 0.19 0.17 0.07
129 INT263722 Dlg4 Regulation of Localization of Grin2b 1 0.15 0.17 0.07
130 INT263740 Dlg4 Regulation of Localization of Gria2 1 0.11 0.17 0.07
131 INT263724 Positive_regulation of Binding of Dlg4 and Neto1 1 0.28 0 0.06
132 INT346754 Binding of Dlg4 and Gria2 1 0.02 0 0.06
133 INT263751 Binding of Dlg4 and Spna1 1 0.03 0 0.05
134 INT263778 Localization of Neto1 Regulation of Localization of Dlg4 1 0.26 0.18 0.05
135 INT340427 Positive_regulation of P2rx7 Positive_regulation of Regulation of Pkhd1 1 0.01 1 0.05
136 INT272598 Dlg4 Positive_regulation of Gene_expression of Gria2 1 0.03 0.53 0.04
137 INT272593 Dlg4 Positive_regulation of Clc 1 0.11 0.54 0.04
138 INT354963 Binding of Cttn and Shank1 1 0.12 0 0.04
139 INT270825 P2rx7 Positive_regulation of Slc37a4 1 0.01 0 0.04
140 INT354971 Binding of HOMER1 and Shank1 1 0.01 0 0.04
141 INT272591 Dlg4 Positive_regulation of Gene_expression of Clybl 1 0.09 0.53 0.04
142 INT272590 Dlg4 Positive_regulation of Clybl 1 0.09 0.52 0.04
143 INT272599 Dlg4 Positive_regulation of Gene_expression of Clc 1 0.11 0.54 0.04
144 INT303170 Gene_expression of Trim3 Negative_regulation of Shank1 1 0.40 0.12 0.04
145 INT272603 Binding of Dlg4 and Nlgn2 1 0.23 0 0.03
146 INT272600 Binding of Dlg4 and Grik5 1 0.20 0 0.03
147 INT272597 Binding of Dlg4 and Kcna4 1 0.17 0 0.03
148 INT263788 Positive_regulation of Binding of GRIN1 and Dlg4 1 0.24 0 0.03
149 INT272596 Binding of Dlg4 and Lrp1 1 0.16 0 0.03
150 INT272606 Binding of Dlg4 and Grin2c 1 0.18 0 0.03
151 INT272604 Binding of Dlg4 and Nlgn3 1 0.17 0 0.03
152 INT272601 Binding of Dlg4 and Grik2 1 0.22 0 0.03
153 INT272594 Binding of Dlg4 and Shank1 1 0.20 0 0.03
154 INT282503 Binding of ocd and Dlgap3 1 0.28 1.58 0.03
155 INT327404 Binding of Xiap and Siva1 1 0.02 1.97 0.03
156 INT272609 Binding of Cit and Dlg4 1 0.11 0 0.03
157 INT198780 Regulation of Binding of Dlg4 and Psd 1 0.14 0 0.03
158 INT303159 Trim3 Negative_regulation of Gene_expression of Shank1 1 0.40 0 0
159 INT346742 Binding of Cacng2 and Dlg4 1 0.03 0 0
160 INT263791 Binding of DLG3 and Dlg4 1 0.20 0 0
161 INT272592 Binding of Dlg4 and Sh3 1 0.11 0.13 0
162 INT132849 Homer1 Regulation of Srf 1 0.01 0.15 0
163 INT287609 Fmr1 Regulation of Protein_catabolism of Dlg4 1 0.05 0.06 0
164 INT278369 Ctsb Positive_regulation of Casp1 1 0.03 0 0
165 INT263726 Binding of Dlg1 and Dlg4 1 0.04 0 0
166 INT303185 Binding of Shank1 and Trim3 1 0.35 0 0
167 INT226045 Binding of Casp1 and Lta 1 0.04 0.73 0
168 INT217031 Binding of P2rx7 and Positive_regulation of Casp1 1 0.02 0 0
169 INT272610 Binding of NA and Dlg4 1 0.41 0.13 0
170 INT287077 Chrm2 Positive_regulation of Homer1 1 0.05 0.08 0
171 INT270831 Positive_regulation of Panx1 Positive_regulation of NLRP3 1 0.18 0.1 0
172 INT199861 Xiap Regulation of Gopc 1 0.07 0.46 0
173 INT303161 Gene_expression of Trim3 Positive_regulation of Shank1 1 0.44 0 0
174 INT226042 Binding of Casp1 and Casp3 1 0.02 0.73 0
175 INT217032 Binding of P2rx7 and Positive_regulation of Il1 1 0.02 0 0
176 INT313272 Binding of DLG4 and GRIN1 1 0.09 0.06 0
177 INT346747 Binding of Dlg4 and Shisa9 1 0.01 0 0
178 INT115239 Binding of Casp1 and EXOSC3 1 0.40 0.11 0
179 INT303169 Trim3 Regulation of Gene_expression of Shank1 1 0.42 0 0
180 INT272264 Dlg4 Regulation of Psd 1 0.22 0.09 0
181 INT346744 Binding of Dlg4 and Tinagl1 1 0.03 0 0
182 INT216942 Positive_regulation of P2rx7 Positive_regulation of Casp1 1 0.14 0 0
183 INT307460 P2rx7 Positive_regulation of Phosphorylation of Gsk3a 1 0.02 0 0
184 INT115240 Binding of Casp1 and TPPP3 1 0.52 0.11 0
185 INT287619 Fmr1 Regulation of Dlg4 1 0.12 0.06 0
186 INT303163 Shank1 Positive_regulation of Trim3 1 0.47 0 0
187 INT303173 Negative_regulation of Trim3 Negative_regulation of Shank1 1 0.40 0 0
188 INT270836 CBX1 Negative_regulation of Panx1 1 0.09 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for scaffold protein binding. They are ordered first by their pain relevance and then by number of times they were reported in scaffold protein binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7898 Gene_expression of Homer1 123 0.78 31.52 53.67
2 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
3 INT7899 Positive_regulation of Gene_expression of Homer1 41 0.70 7.29 25.98
4 INT47818 Positive_regulation of Homer1 48 0.70 11.11 24.05
5 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
6 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
7 INT97100 Negative_regulation of Dlg4 16 0.58 6.18 14.36
8 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
9 INT88789 Gene_expression of Dlg4 26 0.78 4.41 12.74
10 INT69035 Positive_regulation of Casp1 43 0.69 25.18 10.67
11 INT73427 Localization of P2rx7 24 0.79 8.65 9.87
12 INT60995 Negative_regulation of Positive_regulation of Homer1 9 0.38 1.63 9.63
13 INT15242 Regulation of Gene_expression of Homer1 14 0.62 4.33 9.28
14 INT108643 Gene_expression of Dlg4 61 0.76 8.63 8.58
15 INT70848 Gene_expression of Casp1 24 0.77 10.97 8.52
16 INT48257 Negative_regulation of P2rx7 18 0.41 7.82 8.42
17 INT69033 Negative_regulation of Casp1 21 0.58 13.15 7.52
18 INT97099 Positive_regulation of Dlg4 13 0.60 3.04 6.98
19 INT88786 Binding of Dlg4 11 0.46 2.73 6.58
20 INT81586 Negative_regulation of Casp1 11 0.57 6.55 6.45
21 INT90077 Gene_expression of Casp1 29 0.76 20.79 6.26
22 INT88326 Negative_regulation of P2rx7 16 0.58 8.77 6.25
23 INT94608 Regulation of P2rx7 19 0.23 8.06 6.19
24 INT68882 Binding of P2rx7 16 0.23 4.33 6.17
25 INT71220 Positive_regulation of Casp1 15 0.38 10.23 5.84
26 INT145680 Regulation of P2rx7 22 0.61 11.92 5.42
27 INT53974 Regulation of Homer1 14 0.39 4.71 4.9
28 INT88790 Negative_regulation of Gene_expression of Dlg4 6 0.59 1.53 4.66
29 INT145532 Localization of Dlg4 25 0.79 1.97 4.36
30 INT185484 Positive_regulation of Gene_expression of P2rx7 8 0.31 7.44 4.28
31 INT88787 Transcription of Dlg4 4 0.69 0.83 4.09
32 INT120810 Binding of Dlg4 38 0.41 3.55 4.03
33 INT144830 Positive_regulation of Gene_expression of P2rx7 22 0.68 9.78 3.92
34 INT9798 Negative_regulation of Gene_expression of Homer1 10 0.41 2.04 3.77
35 INT60714 Regulation of Positive_regulation of Homer1 3 0.04 0.64 3.46
36 INT129441 Regulation of Gene_expression of P2rx7 8 0.24 4.29 3.32
37 INT144828 Binding of P2rx7 19 0.47 7.84 3.16
38 INT58173 Negative_regulation of Homer1 5 0.43 1 2.79
39 INT82278 Positive_regulation of Positive_regulation of Homer1 5 0.13 2.32 2.73
40 INT107433 Localization of Casp1 6 0.56 2.44 2.64
41 INT107216 Negative_regulation of Gene_expression of P2rx7 10 0.56 3.39 2.61
42 INT156876 Positive_regulation of Gene_expression of Casp1 10 0.50 10.25 2.58
43 INT205692 Positive_regulation of Positive_regulation of Casp1 5 0.46 3 2.44
44 INT144829 Localization of P2rx7 12 0.79 2.92 2.12
45 INT134874 Regulation of Dlg4 3 0.58 0.28 2.12
46 INT198748 Regulation of Gene_expression of Dlg4 10 0.44 2.16 1.85
47 INT61845 Transcription of Homer1 9 0.72 2.28 1.85
48 INT216936 Negative_regulation of Gene_expression of P2rx7 5 0.42 2.59 1.84
49 INT63520 Localization of Homer1 4 0.75 0.38 1.63
50 INT23786 Positive_regulation of Positive_regulation of P2rx7 5 0.44 2.21 1.58
51 INT125735 Transcription of P2rx7 3 0.62 1.34 1.58
52 INT119219 Localization of Dlg4 3 0.64 0.16 1.5
53 INT152939 Regulation of Dlg4 9 0.60 1.09 1.49
54 INT215757 Transcription of P2rx7 3 0.21 1.84 1.45
55 INT205691 Regulation of Gene_expression of P2rx7 5 0.44 3.25 1.42
56 INT134873 Phosphorylation of Dlg4 3 0.80 0.5 1.42
57 INT191678 Gene_expression of Xiap 60 0.71 57.25 1.37
58 INT69034 Regulation of Casp1 3 0.27 3.56 1.36
59 INT82279 Regulation of Negative_regulation of Homer1 1 0.02 0 1.36
60 INT205690 Positive_regulation of Positive_regulation of P2rx7 14 0.68 6.26 1.3
61 INT97098 Regulation of Negative_regulation of Dlg4 3 0.45 0.97 1.3
62 INT96073 Localization of Casp1 11 0.78 4.91 1.29
63 INT73590 Positive_regulation of Positive_regulation of Casp1 2 0.19 1.94 1.28
64 INT145993 Positive_regulation of Xiap 4 0.67 4.4 1.16
65 INT128413 Positive_regulation of Shank1 2 0.70 0.61 1.16
66 INT198750 Positive_regulation of Gene_expression of Dlg4 5 0.68 0.6 1.02
67 INT267750 Binding of Casp1 4 0.35 1.53 1.02
68 INT216661 Regulation of Positive_regulation of P2rx7 1 0.07 0 1
69 INT113887 Positive_regulation of Negative_regulation of P2rx7 1 0.22 1.02 0.96
70 INT128411 Regulation of Shank1 2 0.45 0.81 0.95
71 INT134876 Negative_regulation of Phosphorylation of Dlg4 1 0.35 0.27 0.93
72 INT134878 Negative_regulation of Negative_regulation of Dlg4 1 0.35 0.27 0.93
73 INT9797 Binding of Homer1 2 0.48 1.14 0.9
74 INT115238 Positive_regulation of Gene_expression of Casp1 5 0.68 1.78 0.88
75 INT96074 Negative_regulation of Gene_expression of Casp1 4 0.57 2.77 0.87
76 INT151776 Positive_regulation of Transcription of P2rx7 1 0.03 0.53 0.86
77 INT205685 Regulation of Positive_regulation of Casp1 3 0.11 1.62 0.78
78 INT271589 Regulation of Transcription of P2rx7 1 0.05 0.5 0.78
79 INT169844 Positive_regulation of Localization of Dlg4 2 0.49 0.07 0.75
80 INT182049 Protein_catabolism of Casp1 3 0.20 1.64 0.73
81 INT163783 Transcription of Casp1 1 0.58 0.88 0.73
82 INT163785 Positive_regulation of Transcription of Casp1 1 0.42 0.89 0.73
83 INT204795 Gene_expression of Xiap 9 0.60 15.32 0.7
84 INT70156 Regulation of Casp1 2 0.15 0.79 0.7
85 INT138237 Negative_regulation of Negative_regulation of Casp1 1 0.30 0.56 0.69
86 INT353369 Regulation of Localization of Dlg4 1 0.23 0 0.69
87 INT125734 Negative_regulation of Transcription of P2rx7 1 0.38 0.81 0.67
88 INT156376 Negative_regulation of Transcription of Dlg4 1 0.56 0.16 0.65
89 INT185485 Negative_regulation of Localization of P2rx7 1 0.26 0.95 0.62
90 INT76505 Positive_regulation of Transcription of Homer1 3 0.21 0.48 0.59
91 INT354944 Negative_regulation of Shank3 1 0.59 1.18 0.59
92 INT71172 Negative_regulation of Gene_expression of Casp1 2 0.58 1.3 0.58
93 INT84854 Regulation of Transcription of Homer1 1 0.00 0.15 0.57
94 INT270809 Gene_expression of Panx1 1 0.69 0.59 0.55
95 INT198749 Negative_regulation of Dlg4 8 0.53 2.14 0.54
96 INT198744 Negative_regulation of Gene_expression of Dlg4 6 0.42 1.73 0.54
97 INT243864 Gene_expression of DLG4 5 0.34 0.22 0.54
98 INT138236 Positive_regulation of Localization of Casp1 2 0.48 0.82 0.54
99 INT153321 Positive_regulation of Gene_expression of Dlg4 3 0.49 0.31 0.53
100 INT90078 Negative_regulation of Positive_regulation of Casp1 2 0.42 1.38 0.53
101 INT92523 Phosphorylation of Homer1 3 0.63 0.15 0.52
102 INT156377 Regulation of Binding of Dlg4 1 0.43 0.17 0.51
103 INT198755 Positive_regulation of Dlg4 7 0.59 0.6 0.5
104 INT153099 Negative_regulation of Positive_regulation of P2rx7 1 0.42 0.25 0.5
105 INT191671 Positive_regulation of Xiap 5 0.67 4.63 0.49
106 INT215732 Negative_regulation of Binding of P2rx7 1 0.11 0.74 0.49
107 INT218919 Negative_regulation of Xiap 4 0.32 4.61 0.46
108 INT354955 Gene_expression of Shank3 1 0.78 3.23 0.45
109 INT278114 Negative_regulation of Negative_regulation of P2rx7 1 0.21 0 0.45
110 INT215741 Positive_regulation of Transcription of P2rx7 1 0.15 1.15 0.43
111 INT203253 Protein_catabolism of Xiap 1 0.92 20.16 0.43
112 INT107432 Negative_regulation of Localization of Casp1 1 0.03 0 0.42
113 INT117939 Transcription of Casp1 1 0.27 0.89 0.4
114 INT303211 Gene_expression of Shank1 1 0.64 0.48 0.4
115 INT117938 Negative_regulation of Transcription of Casp1 1 0.22 0.89 0.4
116 INT270810 Localization of Panx1 1 0.67 0.33 0.34
117 INT121239 Regulation of Positive_regulation of P2rx7 2 0.61 1.32 0.32
118 INT296258 Negative_regulation of Localization of Dlg4 1 0.32 0 0.32
119 INT216937 Regulation of Binding of P2rx7 1 0.44 0.08 0.29
120 INT298971 Positive_regulation of Localization of Casp1 2 0.06 0.97 0.28
121 INT218918 Regulation of Gene_expression of Xiap 1 0.29 0.55 0.27
122 INT270811 Negative_regulation of Panx1 1 0.52 0.4 0.27
123 INT354948 Regulation of Shank3 1 0.45 0.69 0.26
124 INT178027 Negative_regulation of Xiap 14 0.54 11.62 0.24
125 INT317821 Regulation of Gene_expression of Casp1 1 0.05 1.74 0.24
126 INT216938 Negative_regulation of Localization of P2rx7 1 0.37 0.25 0.24
127 INT282473 Gene_expression of Dlgap3 1 0.71 3.11 0.23
128 INT216940 Negative_regulation of Binding of P2rx7 1 0.37 0.15 0.2
129 INT270812 Transcription of Panx1 1 0.54 0.26 0.19
130 INT270803 Negative_regulation of Transcription of Panx1 1 0.33 0.26 0.19
131 INT272255 Regulation of Positive_regulation of Dlg4 1 0.39 0.06 0.19
132 INT243875 Positive_regulation of Gene_expression of DLG4 1 0.30 0.22 0.19
133 INT216889 Phosphorylation of P2rx7 1 0.23 0 0.18
134 INT272253 Negative_regulation of Regulation of Dlg4 1 0.37 0 0.18
135 INT204805 Regulation of Xiap 3 0.40 3.98 0.17
136 INT307467 Regulation of Binding of P2rx7 1 0.08 0 0.16
137 INT218922 Phosphorylation of Xiap 1 0.40 0.64 0.16
138 INT193102 Positive_regulation of Gene_expression of Xiap 9 0.64 10.62 0.15
139 INT303216 Protein_catabolism of Shank1 1 0.83 0 0.15
140 INT270813 Positive_regulation of Localization of P2rx7 1 0.46 0.24 0.15
141 INT243883 Negative_regulation of DLG4 1 0.19 0.07 0.15
142 INT198738 Protein_catabolism of Dlg4 5 0.97 0.06 0.12
143 INT203254 Positive_regulation of Protein_catabolism of Xiap 1 0.64 7.46 0.12
144 INT303217 Binding of Shank1 1 0.36 0 0.11
145 INT203260 Negative_regulation of Gene_expression of Xiap 4 0.54 4.54 0.1
146 INT303233 Negative_regulation of Gene_expression of Shank1 1 0.49 0.07 0.1
147 INT267759 Negative_regulation of Binding of Casp1 1 0.04 0.09 0.1
148 INT272257 Positive_regulation of Localization of Dlg4 1 0.43 0 0.1
149 INT307481 Phosphorylation of P2rx7 1 0.15 0.35 0.08
150 INT307480 Positive_regulation of Phosphorylation of P2rx7 1 0.09 0.35 0.08
151 INT270808 Positive_regulation of Gene_expression of Panx1 1 0.62 0.13 0.08
152 INT354949 Positive_regulation of Gene_expression of Shank3 1 0.70 0.45 0.08
153 INT354958 Localization of Shank3 1 0.80 0.4 0.08
154 INT303212 Positive_regulation of Protein_catabolism of Shank1 1 0.42 0 0.08
155 INT156437 Binding of DLG4 2 0.35 0.29 0.07
156 INT282484 Localization of Dlgap3 1 0.74 0.66 0.07
157 INT272574 Gene_expression of Shank1 2 0.61 0.22 0.06
158 INT303195 Positive_regulation of Gene_expression of Shank1 1 0.42 0.08 0.06
159 INT354959 Regulation of Gene_expression of Shank3 1 0.27 1.11 0.06
160 INT270807 Positive_regulation of Localization of Panx1 1 0.39 0.05 0.06
161 INT100988 Regulation of Gene_expression of Dlg4 1 0.36 0.06 0.05
162 INT198746 Regulation of Protein_catabolism of Dlg4 1 0.26 0 0.04
163 INT270806 Positive_regulation of Panx1 1 0.62 0.3 0.04
164 INT303204 Negative_regulation of Shank1 1 0.42 0.11 0.04
165 INT272252 Regulation of Phosphorylation of Dlg4 1 0.44 0 0.04
166 INT203264 Binding of Xiap 5 0.39 5.3 0.03
167 INT204804 Protein_catabolism of Xiap 1 0.59 2.27 0.03
168 INT270801 Binding of Panx1 1 0.33 0 0.03
169 INT204800 Binding of Xiap 1 0.43 3.39 0.03
170 INT204806 Negative_regulation of Binding of Xiap 1 0.38 1.91 0.03
171 INT282478 Positive_regulation of Dlgap3 1 0.46 0.82 0.03
172 INT263696 Transcription of Dlg4 2 0.68 0.07 0
173 INT303227 Regulation of Negative_regulation of Shank1 1 0.26 0 0
174 INT282475 Negative_regulation of Dlgap3 1 0.39 0.7 0
175 INT354953 Negative_regulation of Gene_expression of Shank3 1 0.59 0.36 0
176 INT203256 Regulation of Gene_expression of Xiap 1 0.57 2.82 0
177 INT204796 Localization of Xiap 1 0.63 0.1 0
178 INT354960 Binding of Shank3 1 0.32 0 0
179 INT204809 Positive_regulation of Gene_expression of Xiap 1 0.45 1.6 0
180 INT272578 Phosphorylation of Dlg4 1 0.69 0 0
181 INT203265 Regulation of Xiap 1 0.41 7.93 0
182 INT348166 Localization of DLG4 1 0.11 1.13 0
183 INT270805 Positive_regulation of Positive_regulation of Panx1 1 0.45 0.13 0
184 INT203257 Negative_regulation of Positive_regulation of Xiap 1 0.39 0.68 0
185 INT198741 Negative_regulation of Binding of Dlg4 1 0.36 0 0
186 INT303202 Negative_regulation of Protein_catabolism of Shank1 1 0.49 0 0
187 INT303209 Positive_regulation of Positive_regulation of Shank1 1 0.34 0 0
188 INT203252 Localization of Xiap 1 0.69 2.15 0
189 INT353117 Negative_regulation of Positive_regulation of Casp1 1 0.06 1.25 0
190 INT203258 Negative_regulation of Protein_catabolism of Xiap 1 0.39 1.02 0
191 INT270799 Negative_regulation of Positive_regulation of Panx1 1 0.33 0 0
192 INT263677 Positive_regulation of Binding of Dlg4 1 0.21 0 0
193 INT198745 Regulation of Binding of Dlg4 1 0.44 0 0
194 INT303193 Localization of Shank1 1 0.62 0.19 0
195 INT303199 Regulation of Gene_expression of Shank1 1 0.23 0 0
196 INT354939 Positive_regulation of Gene_expression of Shank1 1 0.45 0.14 0
197 INT303232 Regulation of Protein_catabolism of Shank1 1 0.38 0 0
198 INT270802 Negative_regulation of Gene_expression of Panx1 1 0.33 0 0
199 INT270804 Regulation of Panx1 1 0.35 0.06 0
200 INT354946 Positive_regulation of Shank3 1 0.50 0 0
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