GO:2000054

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Name negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification
Categary Process
Go Slim No
Go Link GO:2000054
Unique Molecular Interactions 17
Total Molecular Interactions 34
Total Single Events 147
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT335886 Binding of Sost and Lrp4 1 0.28 0.65 0.07
2 INT254433 Binding of Lrp5 and Sost 2 0.39 1.51 0.03
3 INT302311 PTH Negative_regulation of Gene_expression of SOST 1 0.29 0.59 0
4 INT293982 MYC Negative_regulation of SFRP1 1 0.21 0.62 0
5 INT302321 Negative_regulation of Binding of Lrp6 and SOST 1 0.16 0.26 0
6 INT302322 Negative_regulation of Binding of Lrp5 and SOST 1 0.16 0.26 0
7 INT251072 Wnt3a Positive_regulation of Axin2 1 0.23 0.29 0
8 INT254432 Binding of Best1 and Sost 1 0.12 0.69 0
9 INT302320 Binding of Lrp6 and SOST 1 0.18 0.26 0
10 INT283361 AXIN2 Negative_regulation of GSK 1 0.09 1.67 0
11 INT302323 Binding of SOST and Wnt2 1 0.02 0.26 0
12 INT302319 Binding of Lrp5 and SOST 1 0.18 0.26 0
13 INT347123 Binding of Axin2 and Lrp1 1 0.08 0.2 0
14 INT315194 Binding of SFRP1 and Slc10a1 1 0.02 8.85 0
15 INT283362 AXIN2 Negative_regulation of APC 1 0.10 1.67 0
16 INT304023 SFRP1 Regulation of Binding of MSI1 1 0.04 1.78 0
17 INT315187 Binding of SFRP1 and COPD 1 0.01 4.47 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT47039 Regulation of SFRP1 14 0.62 7.44 0.92
2 INT335876 Negative_regulation of Sost 11 0.51 6.77 0.67
3 INT47038 Gene_expression of SFRP1 14 0.67 9.6 0.63
4 INT135366 Localization of SFRP1 4 0.75 1.82 0.47
5 INT302314 Negative_regulation of SOST 5 0.44 2.22 0.33
6 INT335878 Localization of Sost 3 0.69 1.11 0.22
7 INT335864 Gene_expression of Sost 4 0.77 2.36 0.2
8 INT335869 Binding of Sost 6 0.32 1.79 0.18
9 INT302313 Gene_expression of SOST 6 0.67 2.06 0.08
10 INT302317 Positive_regulation of Gene_expression of SOST 4 0.60 1.58 0.08
11 INT325665 Positive_regulation of Axin2 1 0.36 0.59 0.06
12 INT347118 Binding of Axin2 1 0.32 1.63 0.06
13 INT206866 Positive_regulation of SFRP1 7 0.51 3.97 0.05
14 INT302316 Negative_regulation of Gene_expression of SOST 4 0.51 1.36 0.05
15 INT287913 Positive_regulation of Gene_expression of SFRP1 2 0.25 2.12 0.05
16 INT329487 Positive_regulation of Negative_regulation of SOST 1 0.45 0.62 0.05
17 INT335868 Negative_regulation of Gene_expression of Sost 2 0.58 1.12 0.04
18 INT302318 Regulation of SOST 2 0.34 0.46 0.04
19 INT325670 Negative_regulation of Axin2 1 0.31 0.34 0.04
20 INT325666 Regulation of Axin2 1 0.32 0.31 0.04
21 INT325669 Gene_expression of Axin2 4 0.57 1.42 0.03
22 INT226288 Negative_regulation of SFRP1 6 0.43 4.45 0
23 INT205099 Positive_regulation of Gene_expression of AXIN2 1 0.48 3.48 0
24 INT338152 Positive_regulation of Gene_expression of Sost 1 0.69 0.2 0
25 INT205105 Gene_expression of AXIN2 1 0.74 6.6 0
26 INT315189 Binding of SFRP1 1 0.15 2.96 0
27 INT226287 Regulation of Gene_expression of SFRP1 1 0.38 0.37 0
28 INT349907 Negative_regulation of Gene_expression of Axin2 1 0.32 0 0
29 INT338151 Regulation of Sost 1 0.39 0.16 0
30 INT302315 Localization of SOST 1 0.61 0.11 0
31 INT226286 Negative_regulation of Gene_expression of SFRP1 1 0.31 0.7 0
32 INT145371 Negative_regulation of AXIN2 1 0.34 0 0
33 INT294017 Negative_regulation of Localization of SFRP1 1 0.32 0.47 0
34 INT251046 Localization of Axin2 1 0.53 0 0
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