GO:2000107

From wiki-pain
Jump to: navigation, search
Name negative regulation of leukocyte apoptosis
Categary Process
Go Slim No
Go Link GO:2000107
Unique Molecular Interactions 83
Total Molecular Interactions 127
Total Single Events 786
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of leukocyte apoptosis. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of leukocyte apoptosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52
2 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17
3 INT149844 Negative_regulation of Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.26
4 INT149845 Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.24
5 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
6 INT105109 Cxcl12 Positive_regulation of JUN 1 0.01 1.07 1.05
7 INT182208 Binding of CXCR2 and CXCL12 1 0.29 1.26 0.95
8 INT182198 Binding of CXCR5 and CXCL12 1 0.33 1.25 0.94
9 INT182209 Binding of CXCL12 and CXCL13 1 0.30 1.24 0.93
10 INT166135 Regulation of Binding of Cxcl12 and Cxcr4 1 0.30 0.9 0.91
11 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
12 INT181437 Binding of Ccr7 and Ccl21b 1 0.01 2.23 0.87
13 INT254004 Cxcl12 Positive_regulation of Cxcr4 1 0.47 1.29 0.86
14 INT181452 Binding of Ccl19 and Ccl21b 1 0.02 2.22 0.86
15 INT253995 Binding of Cxcl12 and Cyp3a23/3a1 1 0.06 1.28 0.85
16 INT254352 Binding of CXCR4 and Positive_regulation of Gene_expression of CXCL12 1 0.14 1.8 0.66
17 INT295724 CXCL12 Positive_regulation of MMP9 1 0.02 0.32 0.6
18 INT253998 Cyp3a23/3a1 Positive_regulation of Binding of Cxcl12 1 0.10 0.65 0.55
19 INT253990 Cyp3a23/3a1 Positive_regulation of Cxcl12 1 0.09 0.65 0.55
20 INT105110 Cxcl12 Positive_regulation of NFKB1 1 0.06 0.54 0.53
21 INT105108 Negative_regulation of Cxcl12 Positive_regulation of NFKB1 1 0.05 0.54 0.53
22 INT181441 Csf2 Positive_regulation of Cxcl12 1 0.02 1.69 0.39
23 INT181439 Csf2 Positive_regulation of Ccl19 1 0.06 1.68 0.38
24 INT208571 CCL21 Positive_regulation of Gene_expression of CCL16 1 0.51 0.63 0.38
25 INT7893 Binding of Oprm1 and Ccl21b 1 0.00 0.08 0.35
26 INT252292 CCL21 Regulation of Binding of Mthfd1 1 0.03 0.41 0.33
27 INT190290 Binding of CXCL12 and VIPR1 1 0.06 0 0.33
28 INT322964 Binding of IL8 and Cxcl12 1 0.30 0.2 0.32
29 INT225021 PDGFB Positive_regulation of Ccl21 1 0.10 0.07 0.3
30 INT225026 PDGFB Positive_regulation of Gene_expression of Ccl21 1 0.10 0.07 0.3
31 INT333246 Binding of Cxcr4 and Cxcl12 3 0.34 0.99 0.27
32 INT291352 Positive_regulation of CXCL12 Positive_regulation of ERBB2 1 0.17 0.88 0.22
33 INT253991 Negative_regulation of Binding of Cxcl12 and Cxcr4 1 0.43 0.41 0.21
34 INT276301 Binding of CCL21 and CXCL13 1 0.04 1.85 0.18
35 INT333250 Binding of Cxcr7 and Cxcl12 1 0.19 1.39 0.18
36 INT353361 Positive_regulation of Binding of Cxcr4 and Cxcl12 1 0.46 0 0.17
37 INT291354 CXCL12 Positive_regulation of EPHB2 1 0.42 2.02 0.16
38 INT333255 Cxcl12 Regulation of Mcl1 1 0.12 1.12 0.15
39 INT333241 Cxcl12 Regulation of Bcl2l11 1 0.18 1.11 0.15
40 INT353359 Binding of Cxcl12 and Regulation of Nes 1 0.25 0.3 0.15
41 INT353360 Binding of Cxcl12 and Positive_regulation of Gene_expression of Hist1h3f 1 0.03 0.3 0.15
42 INT181842 PHB2 Regulation of CCR7 1 0.00 0.7 0.14
43 INT352073 Positive_regulation of Binding of ADAM11 and CCL19 1 0.22 1.27 0.13
44 INT352080 Binding of ADAM11 and CCL19 1 0.16 1.27 0.13
45 INT333242 Bcl2l11 Positive_regulation of Gene_expression of Cxcl12 1 0.18 1.48 0.1
46 INT265388 CCL21 Positive_regulation of Gene_expression of CXCL9 1 0.13 0.88 0.1
47 INT265389 CCL21 Positive_regulation of Gene_expression of CXCL10 1 0.16 0.88 0.1
48 INT291358 Binding of CXCL12 and CXCR7 1 0.20 0.11 0.09
49 INT333251 Binding of Bcl2l11 and Cxcl12 1 0.14 1.74 0.08
50 INT249968 Cxcr4 Positive_regulation of Cxcl12 1 0.17 0.55 0.08
51 INT333256 Gene_expression of Cxcl12 Negative_regulation of Ptk2b 1 0.10 0.99 0.07
52 INT333260 Gene_expression of Cxcl12 Negative_regulation of Gene_expression of Ptk2 1 0.21 1 0.07
53 INT333247 Gene_expression of Cxcl12 Negative_regulation of Pxn 1 0.09 1 0.07
54 INT333243 Gene_expression of Cxcl12 Negative_regulation of Bcar1 1 0.15 1 0.07
55 INT333257 Gene_expression of Cxcl12 Negative_regulation of Ptk2 1 0.21 1 0.07
56 INT291355 CXCL12 Positive_regulation of Gene_expression of HGF 1 0.06 1.53 0.06
57 INT225023 PDGFB Regulation of Transcription of Ccl21 1 0.11 0 0.06
58 INT225022 PDGFB Regulation of Ccl21 1 0.11 0 0.06
59 INT345307 CXCL12 Positive_regulation of Gene_expression of MMP15 1 0.00 2.5 0.05
60 INT224310 EPAS1 Positive_regulation of CXCL12 1 0.02 0.63 0.05
61 INT333254 Binding of Mcl1 and Cxcl12 1 0.10 0.88 0.04
62 INT333244 Positive_regulation of Binding of Mcl1 and Cxcl12 1 0.13 0.88 0.04
63 INT337174 Binding of TLR3 and Positive_regulation of CCR7 1 0.15 0.31 0.03
64 INT291356 CXCL12 Positive_regulation of AKT1 1 0.04 1.28 0.03
65 INT352074 ADAM11 Positive_regulation of Gene_expression of CCL19 1 0.17 0.74 0.03
66 INT333249 Cxcl12 Positive_regulation of Positive_regulation of Bak1 1 0.30 0.32 0.03
67 INT121650 Negative_regulation of Binding of CXCL12 and CXCR4 2 0.47 1.61 0
68 INT245071 Binding of CXCL12 and KDELR1 1 0.04 1.49 0
69 INT121652 Binding of CCR5 and CXCL12 1 0.33 0.2 0
70 INT333258 Gene_expression of Cxcl12 Positive_regulation of Positive_regulation of Bak1 1 0.15 0.55 0
71 INT121649 Binding of CD4 and CXCL12 1 0.29 0.2 0
72 INT245077 Binding of ESR1 and CXCL12 1 0.06 1.42 0
73 INT299130 Cxcl12 Positive_regulation of Gene_expression of Fgf2 1 0.15 0.38 0
74 INT299140 Cxcl12 Positive_regulation of Transcription of VEGFA 1 0.03 0.38 0
75 INT352082 Binding of CCR7 and ADAM11 1 0.15 0.76 0
76 INT333248 Bcl2l11 Regulation of Gene_expression of Cxcl12 1 0.11 0.52 0
77 INT299129 Cxcl12 Positive_regulation of Transcription of Fgf2 1 0.16 0.38 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of leukocyte apoptosis. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of leukocyte apoptosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108480 Gene_expression of CCL21 53 0.77 37.87 14.42
2 INT108485 Gene_expression of CXCL12 61 0.75 49.34 13.79
3 INT108479 Positive_regulation of CCL21 18 0.67 19.93 10.76
4 INT222233 Gene_expression of Cxcl12 42 0.69 32.64 10.13
5 INT126478 Gene_expression of Cxcl12 78 0.77 58.69 8.01
6 INT116717 Gene_expression of CCR7 37 0.76 34.1 7.48
7 INT136309 Positive_regulation of Cxcl12 24 0.62 12.45 5.58
8 INT166966 Gene_expression of Ccr7 14 0.48 7.36 4.2
9 INT181414 Gene_expression of Ccl19 12 0.74 9.8 4.11
10 INT121661 Binding of CXCL12 25 0.37 11.27 3.82
11 INT108481 Positive_regulation of CCL19 4 0.44 15.22 3.77
12 INT253983 Binding of Cxcl12 8 0.43 5.33 3.71
13 INT108484 Gene_expression of CCL19 4 0.50 12.56 3.63
14 INT130646 Regulation of CXCL12 14 0.47 7.67 3.48
15 INT181386 Positive_regulation of Cxcl12 12 0.69 15.35 2.84
16 INT126514 Positive_regulation of CCR7 16 0.43 16.21 2.79
17 INT253982 Positive_regulation of Binding of Cxcl12 1 0.45 3.85 2.6
18 INT182224 Binding of CCL21 6 0.34 5.91 2.54
19 INT108483 Positive_regulation of Gene_expression of CCL21 7 0.69 5.76 2.45
20 INT130638 Regulation of Cxcl12 6 0.34 2.91 2.44
21 INT121659 Positive_regulation of CXCL12 8 0.53 9.17 2.36
22 INT108482 Positive_regulation of Gene_expression of CXCL12 7 0.53 9.72 2.36
23 INT222230 Positive_regulation of Gene_expression of Cxcl12 11 0.59 5.26 2.13
24 INT297679 Positive_regulation of Gene_expression of Cxcl12 6 0.69 8.02 2.02
25 INT181368 Gene_expression of Ccl21b 1 0.03 3.48 2.01
26 INT108486 Positive_regulation of Gene_expression of CCL19 2 0.45 6.2 1.79
27 INT253972 Positive_regulation of Positive_regulation of Cxcl12 1 0.45 3.22 1.71
28 INT177509 Regulation of CCL21 6 0.45 5.43 1.66
29 INT113110 Negative_regulation of CXCL12 8 0.43 6.01 1.63
30 INT222227 Localization of Cxcl12 5 0.64 1.61 1.59
31 INT221059 Negative_regulation of CCL21 5 0.28 2.48 1.58
32 INT145921 Localization of CCL21 4 0.73 2.41 1.58
33 INT254252 Localization of Cxcl12 9 0.76 7.17 1.49
34 INT33299 Binding of CCR7 3 0.31 2.88 1.45
35 INT130647 Regulation of Gene_expression of CXCL12 6 0.39 5.01 1.38
36 INT245089 Localization of CXCL12 8 0.65 10.17 1.28
37 INT152010 Positive_regulation of Ccr7 3 0.47 1.46 1.15
38 INT181400 Negative_regulation of Ccl19 3 0.43 1.97 1.13
39 INT211294 Binding of Cxcl12 4 0.45 2.89 1.05
40 INT181354 Binding of Ccr7 2 0.23 1.94 1.01
41 INT181367 Negative_regulation of Ccl21b 1 0.01 1.72 0.98
42 INT222231 Transcription of Cxcl12 4 0.55 2.25 0.91
43 INT182239 Negative_regulation of Gene_expression of CCR7 1 0.36 1.16 0.91
44 INT184687 Transcription of Ccl19 1 0.68 1.04 0.9
45 INT181370 Positive_regulation of Ccl19 2 0.37 2.28 0.77
46 INT300848 Negative_regulation of Cxcl12 3 0.40 2.29 0.69
47 INT145922 Positive_regulation of Positive_regulation of CCL21 1 0.39 0.82 0.69
48 INT181366 Regulation of Ccl21b 1 0.01 0.52 0.69
49 INT116716 Positive_regulation of Gene_expression of CCR7 5 0.68 6.92 0.67
50 INT291371 Positive_regulation of Localization of CXCL12 2 0.35 2.8 0.65
51 INT208591 Negative_regulation of Gene_expression of CCL21 2 0.40 0.92 0.6
52 INT333232 Negative_regulation of Gene_expression of Cxcl12 4 0.42 3.35 0.57
53 INT222238 Regulation of Localization of Cxcl12 1 0.22 0.6 0.55
54 INT136310 Negative_regulation of Cxcl12 3 0.37 3.29 0.51
55 INT252284 Binding of Ccl19 1 0.17 0.54 0.48
56 INT221052 Positive_regulation of Negative_regulation of CCL21 1 0.22 0.85 0.48
57 INT280914 Positive_regulation of Localization of Cxcl12 3 0.44 3.99 0.47
58 INT291367 Negative_regulation of Gene_expression of CXCL12 3 0.32 4.15 0.47
59 INT182236 Transcription of CCR7 2 0.58 1.07 0.47
60 INT281148 Negative_regulation of Transcription of Cxcl12 1 0.26 1.12 0.47
61 INT354384 Regulation of CCL19 1 0.23 1.89 0.47
62 INT281140 Regulation of Binding of Cxcl12 1 0.28 0.93 0.47
63 INT281149 Positive_regulation of Localization of Cxcl12 1 0.31 0.42 0.45
64 INT181358 Transcription of Ccr7 1 0.43 1.33 0.43
65 INT177505 Regulation of CCR7 3 0.38 2.19 0.42
66 INT225008 Gene_expression of Ccl21 1 0.27 0.07 0.36
67 INT225010 Positive_regulation of Ccl21 1 0.20 0.12 0.33
68 INT208587 Transcription of CCL21 2 0.49 0.84 0.3
69 INT177508 Regulation of Gene_expression of CCL21 1 0.27 1.23 0.3
70 INT305840 Positive_regulation of Gene_expression of Ccr7 1 0.27 0.25 0.24
71 INT184699 Localization of Ccl19 1 0.72 0.47 0.24
72 INT274228 Positive_regulation of Positive_regulation of Cxcl12 4 0.44 2.82 0.23
73 INT265418 Negative_regulation of Negative_regulation of CCL21 1 0.20 0.32 0.22
74 INT299139 Positive_regulation of Transcription of Cxcl12 1 0.37 0.28 0.21
75 INT245087 Transcription of CXCL12 2 0.46 2.04 0.2
76 INT333239 Regulation of Gene_expression of Cxcl12 1 0.43 3.48 0.19
77 INT227245 Localization of CCR7 4 0.47 0.74 0.18
78 INT220167 Localization of Ccr7 1 0.31 0.39 0.18
79 INT312713 Protein_catabolism of CXCL12 1 0.37 0.45 0.17
80 INT253969 Regulation of Gene_expression of Cxcl12 3 0.40 1.56 0.15
81 INT184666 Negative_regulation of Localization of Ccl19 1 0.41 0.25 0.15
82 INT253981 Negative_regulation of Gene_expression of Cxcl12 3 0.39 1.7 0.13
83 INT233555 Regulation of Cxcl12 2 0.43 4.12 0.13
84 INT285485 Negative_regulation of Gene_expression of Ccl19 1 0.07 1.15 0.1
85 INT285481 Positive_regulation of Gene_expression of Ccl19 1 0.08 1.15 0.1
86 INT299136 Protein_catabolism of Cxcl12 1 0.56 1.15 0.09
87 INT353357 Regulation of Positive_regulation of Cxcl12 1 0.27 0.62 0.08
88 INT265420 Negative_regulation of Transcription of CCL21 1 0.23 0.52 0.08
89 INT333206 Negative_regulation of Localization of Cxcl12 1 0.41 1.11 0.08
90 INT333233 Negative_regulation of Positive_regulation of Cxcl12 1 0.41 1.11 0.08
91 INT225009 Transcription of Ccl21 1 0.24 0 0.06
92 INT225005 Positive_regulation of Transcription of Ccl21 1 0.18 0 0.06
93 INT352112 Transcription of CCL19 1 0.38 1.37 0.06
94 INT352100 Positive_regulation of Transcription of CCL19 1 0.37 1.38 0.06
95 INT216078 Negative_regulation of CCR7 2 0.27 0.36 0.03
96 INT352095 Regulation of Gene_expression of CCL19 1 0.21 0.68 0.03
97 INT291363 Positive_regulation of Binding of CXCL12 1 0.38 0.36 0.03
98 INT337244 Positive_regulation of Binding of CCR7 1 0.31 0.6 0.03
99 INT352097 Positive_regulation of Positive_regulation of CCR7 1 0.25 1.06 0
100 INT352113 Positive_regulation of Positive_regulation of CCL19 1 0.27 1.06 0
101 INT245083 Regulation of Positive_regulation of CXCL12 1 0.39 1.6 0
102 INT237846 Positive_regulation of Localization of CCL21 1 0.23 0.94 0
103 INT166967 Negative_regulation of Ccr7 1 0.09 0 0
104 INT352098 Negative_regulation of Gene_expression of CCL19 1 0.23 1.48 0
105 INT333210 Regulation of Localization of Cxcl12 1 0.58 0.56 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox