GO:2000110

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Name negative regulation of macrophage apoptosis
Categary Process
Go Slim No
Go Link GO:2000110
Unique Molecular Interactions 110
Total Molecular Interactions 187
Total Single Events 1387
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of macrophage apoptosis. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of macrophage apoptosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
2 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
3 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
4 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
5 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
6 INT189490 Binding of Ccr3 and Ccl5 1 0.33 8.54 2.6
7 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46
8 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03
9 INT275406 Binding of ITIH4 and Ccr5 1 0.09 2.88 0.97
10 INT275390 Binding of Ccr5 and Htatsf1 1 0.01 3.26 0.97
11 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
12 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
13 INT222243 Negative_regulation of Binding of Trpv1 and Ccr5 1 0.21 0.57 0.86
14 INT222244 Binding of Trpv1 and Ccr5 1 0.19 0.57 0.86
15 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
16 INT87490 CALCA Positive_regulation of Gene_expression of CCL5 1 0.30 0.14 0.81
17 INT149493 PNOC Negative_regulation of CCL5 1 0.14 0.16 0.77
18 INT258644 Binding of CCL2 and CCL5 1 0.36 1.6 0.74
19 INT258643 Positive_regulation of Binding of CCL2 and CCL5 1 0.49 1.61 0.74
20 INT123494 Binding of Egr1 and Ccr5 1 0.04 0.94 0.71
21 INT297313 Negative_regulation of Binding of Ccr1 and Ccl5 1 0.28 0.74 0.67
22 INT245299 Ccl5 Positive_regulation of Localization of IL8 1 0.11 2.87 0.66
23 INT316831 CCL5 Positive_regulation of Gene_expression of MMP2 1 0.02 0.51 0.59
24 INT162789 Binding of TLR2 and NOD2 1 0.37 0.51 0.57
25 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57
26 INT254637 Bdkrb2 Regulation of Gene_expression of Ccl5 1 0.17 1.22 0.56
27 INT244232 Binding of Ccr5 and Ccl4 3 0.17 1.48 0.55
28 INT275387 Binding of Lamp1 and Ccr5 1 0.01 1.45 0.52
29 INT275405 Binding of GOLPH3 and Ccr5 1 0.00 1.46 0.52
30 INT171278 TNFSF12 Positive_regulation of CCL5 1 0.02 0.93 0.48
31 INT275407 Binding of ERVW-1 and Ccr5 1 0.00 1.74 0.46
32 INT181444 Ccl5 Positive_regulation of Csf2 1 0.07 1.88 0.45
33 INT186758 Il13 Regulation of Ccl5 2 0.17 0.17 0.39
34 INT316830 TNF Regulation of CCL5 1 0.02 1.02 0.39
35 INT123511 TIAF1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0.6 0.37
36 INT123495 Negative_regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
37 INT123493 Regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
38 INT189491 Icam1 Positive_regulation of Transcription of Ccl5 1 0.19 0.64 0.36
39 INT189494 Negative_regulation of Ccr5 Negative_regulation of Gene_expression of Hand1 1 0.16 0.66 0.32
40 INT284229 Binding of ITIH4 and Ccr5 1 0.10 0.27 0.31
41 INT181432 Csf2 Positive_regulation of Ccl5 1 0.03 0.81 0.29
42 INT103279 PGR Negative_regulation of Gene_expression of CCL5 1 0.32 0.31 0.27
43 INT237088 Binding of Cxcl9 and Ccl5 1 0.29 1.51 0.26
44 INT246438 Ccl5 Positive_regulation of Gene_expression of Cd79a 1 0.13 0.83 0.26
45 INT275553 Negative_regulation of Binding of Ccr5 and Ccl3 1 0.05 0.73 0.26
46 INT266802 Dlst Positive_regulation of CCL5 1 0.00 0.95 0.25
47 INT252815 Binding of CCL5 and TNF 1 0.02 0.75 0.25
48 INT290378 NOD2 Negative_regulation of TLR2 1 0.27 0.83 0.23
49 INT290377 NOD2 Negative_regulation of Positive_regulation of TLR2 1 0.24 0.95 0.23
50 INT80286 IFNG Positive_regulation of Gene_expression of CCL5 1 0.24 0.37 0.23
51 INT80287 IL4 Positive_regulation of Gene_expression of CCL5 1 0.21 0.37 0.23
52 INT181445 Binding of Ccr5 and Hand1 1 0.12 1.01 0.22
53 INT196635 CFTR Positive_regulation of Gene_expression of CCL5 1 0.07 0.44 0.21
54 INT295713 PTGER2 Positive_regulation of Regulation of CCL5 1 0.01 0.82 0.21
55 INT170995 Binding of IFNA1 and Positive_regulation of Localization of CCL5 1 0.03 0.34 0.19
56 INT303937 Positive_regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
57 INT303940 Regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
58 INT244240 Binding of IL8 and Ccr5 1 0.03 0.05 0.18
59 INT226344 Gene_expression of IL9 Positive_regulation of CCL5 1 0.07 1.03 0.18
60 INT303938 Binding of GLI2 and CCL5 1 0.01 0 0.18
61 INT246437 Ccl5 Positive_regulation of Regulation of Hand1 1 0.19 0.76 0.17
62 INT284230 Positive_regulation of Binding of ITIH4 and Ccr5 1 0.10 0 0.17
63 INT329795 IL6 Positive_regulation of Transcription of CCL5 1 0.02 0.59 0.17
64 INT204791 Binding of Spg7 and Nod2 1 0.03 0.5 0.16
65 INT246440 Ccl5 Positive_regulation of Positive_regulation of Xcl1 1 0.27 1.28 0.16
66 INT204789 Binding of Tlr2 and Nod2 1 0.23 0.44 0.16
67 INT318305 Binding of NOD2 and NLRP3 1 0.08 1.76 0.15
68 INT284226 Negative_regulation of Binding of Ccr5 and Hivan1 1 0.01 0.27 0.14
69 INT284217 Binding of Ccr5 and Hivan1 1 0.01 0.27 0.14
70 INT352417 Ccl2 Positive_regulation of Ccr5 1 0.06 0.26 0.14
71 INT333652 Binding of Ccr5 and Msc 1 0.10 0.07 0.13
72 INT145830 Mdp1 Positive_regulation of Nod2 1 0.34 0.52 0.13
73 INT284219 Binding of Ccr5 and Avpr1b 1 0.01 0.46 0.12
74 INT171295 CXCL10 Positive_regulation of CCL5 1 0.04 0.06 0.12
75 INT284208 Binding of Ccr5 and Eclc 1 0.08 0.3 0.12
76 INT284220 Binding of Ccr5 and Mela 1 0.12 0.23 0.1
77 INT186767 Ccl11 Regulation of Ccl5 1 0.01 0 0.07
78 INT284222 Binding of Ccr5 and Musd1 1 0.01 0.5 0.07
79 INT171297 TNF Positive_regulation of Localization of CCL5 1 0.17 0.66 0.07
80 INT186766 Il5 Regulation of Ccl5 1 0.01 0 0.07
81 INT284216 Binding of Ccr5 and Arhgap4 1 0.02 0.31 0.07
82 INT246441 Ccl5 Positive_regulation of Gene_expression of Aif1 1 0.03 0.71 0.06
83 INT246436 Ccl5 Regulation of Aif1 1 0.01 0.67 0.06
84 INT284209 Negative_regulation of Binding of Ccr5 and Mela 1 0.14 0.12 0.05
85 INT122216 IL1B Positive_regulation of CCL5 3 0.67 0.53 0.04
86 INT247774 Binding of Ccl5 and Ccrl2 1 0.14 0.29 0.04
87 INT284225 Binding of Cd4 and Ccr5 1 0.30 0.26 0.04
88 INT171279 IL6 Positive_regulation of CCL5 1 0.04 0.38 0.04
89 INT171301 TNF Positive_regulation of CCL5 1 0.16 0.38 0.04
90 INT247766 Binding of Ccl2 and Ccl5 1 0.14 0.28 0.04
91 INT122217 IL1B Positive_regulation of Gene_expression of CCL5 2 0.52 0.08 0
92 INT222259 EIF4E Regulation of Negative_regulation of NOD2 1 0.13 0.1 0
93 INT127690 TNF Positive_regulation of Regulation of CCL5 1 0.33 0.17 0
94 INT171282 TNFSF12 Positive_regulation of Gene_expression of CCL5 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of macrophage apoptosis. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of macrophage apoptosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09
2 INT130186 Gene_expression of Ccl5 101 0.74 79.96 25.01
3 INT78901 Localization of CCL5 67 0.78 40.79 20.59
4 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62
5 INT167679 Gene_expression of Ccr5 74 0.75 59.03 18.16
6 INT168409 Positive_regulation of Ccl5 47 0.64 45.84 10.83
7 INT4240 Positive_regulation of CCL5 32 0.58 20.55 10.65
8 INT87393 Gene_expression of Ccr5 19 0.65 11 10.51
9 INT78895 Regulation of CCL5 30 0.46 20.45 10.18
10 INT87495 Positive_regulation of Gene_expression of CCL5 26 0.69 13.85 9.46
11 INT89589 Negative_regulation of Ccl5 9 0.40 4.62 7.39
12 INT103909 Gene_expression of NOD2 37 0.77 21.9 7.36
13 INT153268 Positive_regulation of Ccr5 25 0.66 19 7.02
14 INT181348 Localization of Ccl5 24 0.65 19.55 6.8
15 INT120089 Negative_regulation of Ccr5 7 0.58 10.36 5.91
16 INT92470 Negative_regulation of Gene_expression of CCL5 15 0.50 5.46 5.86
17 INT103847 Positive_regulation of Ccr5 11 0.55 6.04 5.79
18 INT181406 Binding of Ccr5 16 0.45 17 5.78
19 INT181363 Regulation of Ccl5 16 0.46 13.65 5.09
20 INT181362 Negative_regulation of Ccl5 21 0.40 15.63 4.96
21 INT82887 Positive_regulation of Ccl5 10 0.40 3.4 4.91
22 INT176614 Positive_regulation of Gene_expression of Ccl5 20 0.59 16.2 4.81
23 INT89590 Negative_regulation of Gene_expression of Ccl5 8 0.36 3.97 4.67
24 INT181042 Binding of Ccl5 18 0.41 9.34 4.51
25 INT4239 Negative_regulation of CCL5 15 0.40 10.92 4.26
26 INT103843 Positive_regulation of Gene_expression of Ccr5 5 0.42 2.31 3.89
27 INT103281 Transcription of CCL5 10 0.67 5.95 3.7
28 INT89592 Localization of Ccl5 10 0.61 7.65 3.62
29 INT181378 Negative_regulation of Gene_expression of Ccl5 12 0.46 9.64 3.59
30 INT124123 Positive_regulation of Localization of CCL5 12 0.67 7 3.37
31 INT181418 Regulation of Gene_expression of Ccl5 11 0.52 9.86 3.37
32 INT82879 Regulation of Ccl5 9 0.30 6.19 3.17
33 INT78898 Regulation of Gene_expression of CCL5 9 0.42 5.7 3.11
34 INT115617 Binding of Ccl5 5 0.33 0.58 3.11
35 INT166879 Localization of Ccr5 4 0.71 3.62 2.97
36 INT103910 Binding of NOD2 19 0.47 12.24 2.93
37 INT194661 Binding of CCL5 9 0.46 6.07 2.73
38 INT87395 Binding of Ccr5 5 0.29 2.5 2.6
39 INT181356 Positive_regulation of Gene_expression of Ccr5 11 0.66 8.3 2.24
40 INT96743 Transcription of Ccr5 2 0.54 2.72 2.17
41 INT115616 Positive_regulation of Binding of Ccl5 3 0.25 0.59 2.04
42 INT103061 Positive_regulation of Gene_expression of Ccl5 4 0.35 1.67 1.9
43 INT117221 Positive_regulation of Gene_expression of NOD2 7 0.65 4.39 1.83
44 INT162793 Regulation of NOD2 6 0.45 7.61 1.78
45 INT87394 Negative_regulation of Ccr5 3 0.32 1.3 1.74
46 INT194660 Positive_regulation of Binding of CCL5 1 0.42 2.74 1.72
47 INT78896 Negative_regulation of Localization of CCL5 8 0.57 2.43 1.59
48 INT171015 Positive_regulation of Positive_regulation of CCL5 3 0.42 3.63 1.51
49 INT117219 Positive_regulation of NOD2 9 0.69 4.66 1.31
50 INT115895 Phosphorylation of Ccl5 1 0.55 0 1.31
51 INT204766 Gene_expression of Nod2 4 0.75 4.14 1.3
52 INT149554 Transcription of Ccl5 2 0.59 0.55 1.14
53 INT115893 Negative_regulation of Binding of Ccl5 1 0.37 0 1.14
54 INT208244 Regulation of Gene_expression of Ccl5 1 0.26 1.92 1.01
55 INT154227 Regulation of Gene_expression of NOD2 3 0.44 3.38 0.99
56 INT87396 Negative_regulation of Gene_expression of Ccr5 1 0.12 1.02 0.92
57 INT181351 Transcription of Ccl5 5 0.64 2.19 0.9
58 INT103285 Regulation of Localization of CCL5 3 0.44 1.11 0.89
59 INT149555 Negative_regulation of Positive_regulation of Ccl5 1 0.15 0 0.88
60 INT189482 Regulation of Gene_expression of Ccr5 4 0.44 3.38 0.86
61 INT160410 Positive_regulation of Positive_regulation of Ccr5 2 0.38 1.31 0.83
62 INT181390 Negative_regulation of Positive_regulation of Ccl5 2 0.31 2.31 0.77
63 INT115897 Positive_regulation of Phosphorylation of Ccl5 1 0.41 0 0.66
64 INT115892 Positive_regulation of Phosphorylation of Ccr5 1 0.00 0 0.66
65 INT115896 Phosphorylation of Ccr5 1 0.01 0 0.65
66 INT181364 Regulation of Ccr5 3 0.32 1.81 0.62
67 INT181349 Positive_regulation of Localization of Ccl5 2 0.37 0.89 0.62
68 INT194225 Positive_regulation of Positive_regulation of Ccl5 1 0.07 1.13 0.55
69 INT103844 Regulation of Gene_expression of Ccr5 1 0.22 0.55 0.51
70 INT181376 Negative_regulation of Gene_expression of Ccr5 3 0.41 2.12 0.49
71 INT204781 Positive_regulation of Nod2 6 0.45 2.79 0.46
72 INT181397 Transcription of Ccr5 2 0.62 1.33 0.46
73 INT87392 Regulation of Ccr5 1 0.17 0.53 0.46
74 INT194658 Positive_regulation of Transcription of CCL5 1 0.45 0.68 0.44
75 INT222266 Transcription of NOD2 5 0.68 0.76 0.43
76 INT267606 Protein_catabolism of CCL5 2 0.48 1.39 0.43
77 INT222240 Positive_regulation of Transcription of Ccr5 1 0.37 0.7 0.4
78 INT268760 Positive_regulation of Binding of Ccl5 1 0.13 0.91 0.39
79 INT322698 Protein_catabolism of Ccl5 1 0.49 0.33 0.38
80 INT171764 Localization of NOD2 2 0.74 0.86 0.37
81 INT322707 Protein_catabolism of Ccr5 1 0.22 0.32 0.37
82 INT183240 Negative_regulation of NOD2 6 0.43 1.52 0.33
83 INT195733 Phosphorylation of CCL5 2 0.10 1.04 0.33
84 INT244148 Positive_regulation of Positive_regulation of NOD2 1 0.47 0.68 0.31
85 INT222270 Regulation of Localization of NOD2 1 0.45 0.63 0.28
86 INT346895 Positive_regulation of Gene_expression of Nod2 1 0.33 0.74 0.28
87 INT103283 Negative_regulation of Transcription of CCL5 1 0.50 0.28 0.27
88 INT346896 Binding of Nod2 1 0.21 0.72 0.26
89 INT322710 Positive_regulation of Transcription of Ccl5 1 0.43 0.56 0.26
90 INT282377 Regulation of Positive_regulation of CCL5 1 0.05 1.12 0.22
91 INT346899 Regulation of Positive_regulation of Nod2 1 0.18 0.75 0.22
92 INT284203 Positive_regulation of Negative_regulation of Ccr5 1 0.41 0.41 0.18
93 INT89593 Negative_regulation of Localization of Ccl5 1 0.03 0.46 0.15
94 INT233838 Regulation of Binding of Ccl5 1 0.21 1 0.15
95 INT195730 Negative_regulation of Binding of CCL5 1 0.05 0.51 0.13
96 INT222274 Regulation of Regulation of NOD2 1 0.27 0.45 0.13
97 INT284206 Negative_regulation of Negative_regulation of Ccr5 1 0.40 0 0.12
98 INT204777 Negative_regulation of Localization of Nod2 1 0.28 0.61 0.09
99 INT322703 Negative_regulation of Binding of Ccr5 1 0.32 0.41 0.09
100 INT246434 Negative_regulation of Negative_regulation of Ccl5 1 0.40 1.72 0.09
101 INT204779 Localization of Nod2 1 0.48 0.6 0.08
102 INT204770 Regulation of Nod2 1 0.29 0.66 0.07
103 INT222267 Regulation of Transcription of NOD2 1 0.45 0 0.05
104 INT284205 Phosphorylation of Ccr5 1 0.59 0.08 0.04
105 INT346893 Negative_regulation of Gene_expression of Nod2 1 0.28 0.13 0.04
106 INT284053 Positive_regulation of Positive_regulation of Nod2 1 0.25 0.08 0
107 INT222273 Positive_regulation of Regulation of NOD2 1 0.46 0.09 0
108 INT189478 Regulation of Transcription of Ccl5 1 0.38 0.63 0
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