GO:2000114

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Name regulation of establishment of cell polarity
Categary Process
Go Slim No
Go Link GO:2000114
Unique Molecular Interactions 41
Total Molecular Interactions 58
Total Single Events 361
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of establishment of cell polarity. They are ordered first by their pain relevance and then by number of times they were reported for regulation of establishment of cell polarity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT87267 Binding of BMP8B and KRIT1 1 0.06 0.16 2.69
2 INT87266 Negative_regulation of Binding of BMP8B and KRIT1 1 0.05 0.07 1.37
3 INT87275 KRIT1 Regulation of Oprd1 1 0.01 0.08 0.72
4 INT134080 OPA1 Negative_regulation of Phosphorylation of Gnb2l1 1 0.03 0.22 0.34
5 INT88252 Binding of RAP1A and Krit1 1 0.36 2.25 0.33
6 INT174311 Binding of Krit1 and Rap1a 1 0.04 1.08 0.28
7 INT193031 CHRM2 Positive_regulation of ROCK1 1 0.00 0.12 0.24
8 INT343547 ROCK1 Positive_regulation of Gene_expression of PTHLH 1 0.15 0.2 0.2
9 INT23585 Binding of KRIT1 and CCR1 1 0.40 0.97 0.19
10 INT23586 Binding of CALCR and KRIT1 1 0.40 0.97 0.19
11 INT304964 Binding of AMT and PTK2B 1 0.23 0.78 0.18
12 INT193080 ROCK1 Positive_regulation of Ppp1r14a 1 0.00 0.13 0.18
13 INT267138 Binding of CDH5 and PECAM1 2 0.16 2.69 0.16
14 INT194829 Gata3 Positive_regulation of IL13 1 0.01 0.12 0.15
15 INT194835 Gata3 Positive_regulation of IL5 1 0.01 0.12 0.15
16 INT194833 Binding of IL5 and Gata3 1 0.01 0.12 0.15
17 INT194827 Binding of IL13 and Gata3 1 0.01 0.12 0.15
18 INT338428 Il4 Positive_regulation of Gata3 1 0.06 0.75 0.13
19 INT343542 ROCK1 Positive_regulation of Positive_regulation of PTHLH 1 0.21 0 0.12
20 INT206056 PTK2B Negative_regulation of Positive_regulation of IRF6 1 0.00 0.66 0.1
21 INT111134 Binding of Krit1 and Rap1a 1 0.07 0.81 0.1
22 INT355584 VEGFA Positive_regulation of Positive_regulation of CDH5 1 0.06 1.35 0.09
23 INT322851 Binding of KRIT1 and OSM 1 0.04 1.42 0.09
24 INT265564 Ocln Regulation of Gene_expression of Cdh5 1 0.01 1.03 0.05
25 INT89385 INS Positive_regulation of Phosphorylation of PTK2B 1 0.15 0.59 0.04
26 INT190738 Adcyap1 Positive_regulation of Gene_expression of Gnb2l1 1 0.08 0 0.03
27 INT269584 Binding of CFL1 and ROCK1 1 0.03 0.05 0.03
28 INT343546 Negative_regulation of ROCK1 Negative_regulation of Gene_expression of PTHLH 1 0.16 3.28 0.03
29 INT343545 Binding of GLI2 and ROCK1 1 0.07 0.65 0.03
30 INT343537 ROCK1 Regulation of Gene_expression of PTHLH 1 0.08 0.09 0.03
31 INT290592 Binding of KDR and Cdh5 1 0.07 0.08 0
32 INT290590 Binding of Cdh5 and Prom1 1 0.05 0.08 0
33 INT258209 ROCK1 Regulation of ARR3 1 0.00 0.2 0
34 INT258202 ROCK1 Positive_regulation of MYL2 1 0.14 0.2 0
35 INT261730 ROCK1 Positive_regulation of Positive_regulation of F2R 1 0.37 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of establishment of cell polarity. They are ordered first by their pain relevance and then by number of times they were reported in regulation of establishment of cell polarity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT63701 Localization of KRIT1 11 0.78 2.02 9.17
2 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
3 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
4 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6
5 INT14914 Regulation of Cdh5 5 0.52 4.59 1.85
6 INT48218 Gene_expression of KRIT1 16 0.75 7.59 1.8
7 INT87272 Binding of KRIT1 4 0.47 1.2 1.48
8 INT116014 Transcription of Gata3 4 0.63 2.24 1.46
9 INT116015 Regulation of Gata3 3 0.22 1.41 1.42
10 INT116008 Binding of Gata3 2 0.34 1.37 1.41
11 INT116016 Positive_regulation of Positive_regulation of Gata3 2 0.21 0.5 1.28
12 INT78692 Regulation of PTK2B 2 0.47 0.29 1.28
13 INT118682 Positive_regulation of KRIT1 4 0.67 1.25 1.24
14 INT182474 Gene_expression of Cdh5 17 0.57 14.58 1.23
15 INT126534 Negative_regulation of ROCK1 18 0.49 14.32 1.13
16 INT87273 Positive_regulation of Localization of KRIT1 1 0.67 0.1 1.02
17 INT71599 Phosphorylation of KRIT1 1 0.79 0 0.73
18 INT116012 Regulation of Positive_regulation of Gata3 1 0.20 0.07 0.71
19 INT116006 Positive_regulation of Transcription of Gata3 1 0.21 0.07 0.7
20 INT116010 Positive_regulation of Binding of Gata3 1 0.31 0.07 0.7
21 INT202416 Negative_regulation of Gata3 2 0.32 1.17 0.64
22 INT290660 Negative_regulation of Gene_expression of Gata3 1 0.25 1.52 0.6
23 INT102336 Gene_expression of Krit1 3 0.69 2.54 0.49
24 INT188173 Gene_expression of CDH5 14 0.49 3.17 0.44
25 INT109920 Positive_regulation of PTK2B 5 0.43 2.21 0.43
26 INT142598 Negative_regulation of KRIT1 3 0.57 0.57 0.4
27 INT109922 Negative_regulation of PTK2B 3 0.26 1.63 0.39
28 INT71598 Positive_regulation of Gene_expression of KRIT1 1 0.49 0 0.37
29 INT109919 Positive_regulation of Positive_regulation of PTK2B 1 0.31 0.09 0.35
30 INT134072 Negative_regulation of Phosphorylation of Gnb2l1 1 0.11 0.22 0.34
31 INT134076 Phosphorylation of Gnb2l1 1 0.22 0.22 0.3
32 INT339435 Binding of Cdh5 1 0.31 3.37 0.3
33 INT185436 Gene_expression of ROCK1 5 0.52 6.85 0.29
34 INT258250 Positive_regulation of ROCK1 7 0.51 2.07 0.22
35 INT148791 Negative_regulation of Phosphorylation of Cdh5 2 0.07 0.97 0.22
36 INT185443 Regulation of ROCK1 4 0.18 3.32 0.21
37 INT148790 Phosphorylation of Cdh5 2 0.14 0.97 0.21
38 INT89400 Phosphorylation of PTK2B 4 0.38 1.16 0.19
39 INT182476 Positive_regulation of Gene_expression of Cdh5 5 0.40 1.65 0.17
40 INT150084 Binding of Krit1 6 0.23 0.55 0.16
41 INT277989 Positive_regulation of CDH5 3 0.11 1.66 0.15
42 INT148792 Positive_regulation of Phosphorylation of Cdh5 1 0.08 0 0.14
43 INT266328 Positive_regulation of Cdh5 4 0.40 0.77 0.12
44 INT89409 Negative_regulation of Phosphorylation of PTK2B 2 0.13 0.89 0.12
45 INT194746 Phosphorylation of Gata3 1 0.10 0.08 0.12
46 INT150083 Positive_regulation of Binding of Krit1 1 0.24 0.29 0.1
47 INT135555 Localization of PTK2B 1 0.57 0.32 0.1
48 INT239985 Negative_regulation of Cdh5 2 0.27 0.47 0.08
49 INT339433 Localization of Cdh5 1 0.48 0.37 0.08
50 INT339438 Negative_regulation of Localization of Cdh5 1 0.27 0.37 0.08
51 INT188176 Positive_regulation of Gene_expression of CDH5 3 0.32 0.75 0.07
52 INT158676 Negative_regulation of Gene_expression of KRIT1 1 0.41 0.21 0.07
53 INT160286 Negative_regulation of Krit1 1 0.25 0.19 0.06
54 INT341887 Positive_regulation of Positive_regulation of ROCK1 1 0.01 0.12 0.05
55 INT239993 Negative_regulation of Gene_expression of Cdh5 3 0.31 0.76 0.04
56 INT343555 Regulation of Gene_expression of ROCK1 1 0.15 1.02 0.04
57 INT265545 Regulation of Gene_expression of Cdh5 1 0.05 1.01 0.04
58 INT314241 Transcription of CDH5 1 0.31 0.07 0.04
59 INT192237 Phosphorylation of ROCK1 2 0.19 0.39 0.03
60 INT190723 Gene_expression of Gnb2l1 1 0.17 0 0.03
61 INT343556 Positive_regulation of Gene_expression of ROCK1 1 0.23 1.05 0.03
62 INT200683 Gene_expression of PTK2B 2 0.67 1.02 0
63 INT269651 Positive_regulation of Phosphorylation of ROCK1 1 0.11 0.29 0
64 INT258237 Negative_regulation of Negative_regulation of ROCK1 1 0.32 0.16 0
65 INT243389 Transcription of PTK2B 1 0.64 0.52 0
66 INT200665 Negative_regulation of Gene_expression of PTK2B 1 0.04 0.69 0
67 INT232507 Regulation of CDH5 1 0.15 0.22 0
68 INT269645 Negative_regulation of Positive_regulation of ROCK1 1 0.10 0 0
69 INT156922 Positive_regulation of Phosphorylation of PTK2B 1 0.23 0 0
70 INT308503 Regulation of KRIT1 1 0.11 0 0
71 INT188174 Negative_regulation of Gene_expression of CDH5 1 0.27 0 0
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