GO:2000145

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Name regulation of cell motility
Categary Process
Go Slim No
Go Link GO:2000145
Unique Molecular Interactions 81
Total Molecular Interactions 110
Total Single Events 571
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of cell motility. They are ordered first by their pain relevance and then by number of times they were reported for regulation of cell motility. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT44716 Binding of ABL2 and PDYN 2 0.40 0.66 4.77
2 INT114324 RAF1 Positive_regulation of Phosphorylation of ADCY6 1 0.02 0.05 0.85
3 INT114323 Binding of ADCY6 and RAF1 1 0.02 0.05 0.85
4 INT323148 PRKCA Positive_regulation of RAF1 1 0.01 0 0.55
5 INT323150 PRKCA Positive_regulation of Phosphorylation of RAF1 1 0.01 0 0.55
6 INT221630 Binding of Fes and Plxna1 1 0.01 1.02 0.5
7 INT105169 RAF1 Regulation of Positive_regulation of ADCY1 1 0.12 0 0.4
8 INT124798 RAF1 Regulation of PRKCA 1 0.06 0 0.39
9 INT353454 Binding of BRCA1 and IL17A 1 0.00 2.55 0.36
10 INT353452 Binding of AGRP and BRCA1 1 0.00 3.89 0.34
11 INT109098 Binding of ABL2 and PON1 1 0.36 1.32 0.28
12 INT353448 BRCA1 Positive_regulation of CCL2 1 0.01 1.37 0.26
13 INT353449 BRCA1 Positive_regulation of IL4 1 0.00 1.37 0.26
14 INT353455 BRCA1 Positive_regulation of IL13 1 0.00 1.37 0.26
15 INT118851 GNA14 Positive_regulation of RAF1 1 0.00 0.14 0.26
16 INT193031 CHRM2 Positive_regulation of ROCK1 1 0.00 0.12 0.24
17 INT274578 Binding of ABL1 and PSTPIP1 1 0.07 1.55 0.21
18 INT45934 PKN1 Regulation of NOTCH2NL 1 0.01 0 0.2
19 INT45933 PKN1 Regulation of PKN3 1 0.05 0 0.2
20 INT221642 Binding of Fes and Fer 1 0.32 0.27 0.2
21 INT221641 Binding of Dpysl2 and Fes 1 0.23 0.27 0.2
22 INT343547 ROCK1 Positive_regulation of Gene_expression of PTHLH 1 0.15 0.2 0.2
23 INT193080 ROCK1 Positive_regulation of Ppp1r14a 1 0.00 0.13 0.18
24 INT221632 Plxna1 Negative_regulation of Fes 1 0.02 0.58 0.15
25 INT353451 Binding of BRCA1 and CRP 1 0.01 1.18 0.14
26 INT82802 Binding of ABL2 and POMC 1 0.00 0 0.14
27 INT353453 Binding of BRCA1 and IL4 1 0.00 1.18 0.14
28 INT221662 Fes Positive_regulation of Phosphorylation of Dpysl2 1 0.24 0.14 0.14
29 INT221615 Dpysl2 Positive_regulation of Gene_expression of Fes 1 0.21 0.14 0.13
30 INT221620 Fes Regulation of Gh 1 0.01 0.39 0.12
31 INT343542 ROCK1 Positive_regulation of Positive_regulation of PTHLH 1 0.21 0 0.12
32 INT221634 Fes Regulation of Ngf 1 0.28 0.33 0.12
33 INT252779 Binding of ESR1 and RAF1 1 0.01 2.03 0.11
34 INT274583 Binding of ABL1 and PSTPIP2 1 0.06 0.79 0.11
35 INT252778 RAF1 Positive_regulation of Positive_regulation of ROS1 1 0.04 2.05 0.11
36 INT221659 Binding of Fes and Dpysl5 1 0.16 0.58 0.11
37 INT185278 Binding of CCND1 and CDK6 3 0.13 1.62 0.08
38 INT221655 Plxna1 Negative_regulation of Phosphorylation of Fes 1 0.02 0.17 0.08
39 INT88054 ABL2 Regulation of Gh 1 0.02 0.57 0.08
40 INT221631 Dpysl2 Negative_regulation of Fes 1 0.21 0.42 0.07
41 INT353450 Binding of BRCA1 and VEGFA 1 0.01 0.82 0.05
42 INT221663 Fes Positive_regulation of Binding of Plxna1 1 0.02 0.4 0.05
43 INT354715 Binding of PKN1 and Pick1 1 0.01 0.19 0.04
44 INT354682 Binding of ASIC1 and PKN1 1 0.01 0.19 0.04
45 INT221654 Fes Positive_regulation of Phosphorylation of Crmp1 1 0.18 0.37 0.04
46 INT269584 Binding of CFL1 and ROCK1 1 0.03 0.05 0.03
47 INT343546 Negative_regulation of ROCK1 Negative_regulation of Gene_expression of PTHLH 1 0.16 3.28 0.03
48 INT343545 Binding of GLI2 and ROCK1 1 0.07 0.65 0.03
49 INT221623 Fyn Regulation of Fes 1 0.14 0.2 0.03
50 INT343537 ROCK1 Regulation of Gene_expression of PTHLH 1 0.08 0.09 0.03
51 INT221262 Binding of BRCA1 and CD4 1 0.22 0.81 0.03
52 INT234178 Binding of BRCA1 and BRCA2 2 0.40 1.52 0
53 INT292680 Negative_regulation of TXK Negative_regulation of ABL1 1 0.00 0.26 0
54 INT280568 MRAS Positive_regulation of RAF1 1 0.01 0.7 0
55 INT222868 Binding of Chuk and Pkn1 1 0.00 0 0
56 INT350523 ABL1 Negative_regulation of Pmf1 1 0.01 2.19 0
57 INT258209 ROCK1 Regulation of ARR3 1 0.00 0.2 0
58 INT234180 Binding of BRCA1 and BRIP1 1 0.33 1.37 0
59 INT185281 Binding of CDK6 and CDKN2A 1 0.29 0.87 0
60 INT314743 Binding of RAD51 and Brca1 1 0.06 1.06 0
61 INT314740 Binding of ESR1 and Brca1 1 0.16 0.69 0
62 INT258202 ROCK1 Positive_regulation of MYL2 1 0.14 0.2 0
63 INT291335 Positive_regulation of RAF1 Positive_regulation of Phosphorylation of GSK3A 1 0.07 0.88 0
64 INT232595 Binding of BRCA1 and HEPACAM 1 0.02 0.89 0
65 INT258523 Positive_regulation of RAF1 Positive_regulation of Phosphorylation of GSK 1 0.19 0.64 0
66 INT185280 Binding of CDK4 and CDK6 1 0.20 0.87 0
67 INT225874 Positive_regulation of ras Positive_regulation of RAF1 1 0.00 0 0
68 INT225871 RAF1 Positive_regulation of Mdk 1 0.00 0 0
69 INT327872 Binding of Postn and Pkn1 1 0.03 0.21 0
70 INT259091 Binding of BRCA1 and LMO4 1 0.24 0.74 0
71 INT314745 Binding of TP53 and Brca1 1 0.18 1.17 0
72 INT285582 Binding of ABL1 and S100A8 1 0.02 0.2 0
73 INT221622 Dpysl2 Positive_regulation of Fes 1 0.24 0 0
74 INT225875 ras Positive_regulation of RAF1 1 0.00 0 0
75 INT296162 Mcph1 Regulation of Brca1 1 0.26 0.19 0
76 INT261730 ROCK1 Positive_regulation of Positive_regulation of F2R 1 0.37 0 0
77 INT291331 Negative_regulation of GSK3A Positive_regulation of Positive_regulation of RAF1 1 0.07 0.94 0
78 INT292726 ABL1 Positive_regulation of Mapk1 1 0.01 0.15 0
79 INT221635 Dpysl2 Negative_regulation of Phosphorylation of Fes 1 0.20 0 0
80 INT160602 Binding of ABL2 and ADH1B 1 0.40 0.36 0
81 INT350504 ABL1 Negative_regulation of JAK2 1 0.20 2.18 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of cell motility. They are ordered first by their pain relevance and then by number of times they were reported in regulation of cell motility. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT105171 Phosphorylation of RAF1 11 0.74 2.33 4.19
2 INT119063 Gene_expression of BRCA1 24 0.67 30.04 4.17
3 INT119421 Negative_regulation of RAF1 10 0.41 6.94 3.31
4 INT221269 Binding of BRCA1 14 0.40 31.77 2.7
5 INT114327 Positive_regulation of RAF1 26 0.51 20.87 2.32
6 INT17617 Gene_expression of ABL2 8 0.75 2.73 2.25
7 INT48850 Gene_expression of PKN1 16 0.52 1.93 1.92
8 INT44723 Positive_regulation of ABL2 7 0.49 2.23 1.82
9 INT221422 Positive_regulation of BRCA1 5 0.23 12.63 1.53
10 INT221560 Gene_expression of Fes 36 0.72 6.63 1.51
11 INT119062 Negative_regulation of BRCA1 12 0.49 13.7 1.36
12 INT123877 Negative_regulation of ABL1 40 0.57 27.94 1.17
13 INT127805 Positive_regulation of Phosphorylation of RAF1 3 0.45 1.21 1.17
14 INT126534 Negative_regulation of ROCK1 18 0.49 14.32 1.13
15 INT98174 Positive_regulation of Gene_expression of ABL2 1 0.49 1.1 1.05
16 INT250699 Binding of CDK6 3 0.33 2.54 0.97
17 INT221543 Binding of Fes 1 0.45 1.79 0.83
18 INT48851 Positive_regulation of Gene_expression of PKN1 2 0.27 0.67 0.78
19 INT221557 Phosphorylation of Fes 1 0.76 2.49 0.76
20 INT114405 Regulation of Pkn1 1 0.44 1.58 0.61
21 INT221420 Positive_regulation of Gene_expression of BRCA1 2 0.24 2.17 0.55
22 INT172310 Positive_regulation of PKN1 6 0.12 2 0.51
23 INT323167 Negative_regulation of Phosphorylation of RAF1 1 0.08 0 0.43
24 INT252737 Gene_expression of RAF1 12 0.58 10.97 0.42
25 INT77493 Regulation of ABL2 1 0.26 0.71 0.42
26 INT117662 Gene_expression of ABL1 21 0.69 18.76 0.39
27 INT65292 Binding of ABL2 2 0.36 0 0.39
28 INT82806 Negative_regulation of ABL2 3 0.41 0.58 0.37
29 INT73854 Transcription of ABL1 4 0.52 2.26 0.34
30 INT353457 Positive_regulation of Binding of BRCA1 1 0.09 1.69 0.34
31 INT221419 Regulation of BRCA1 5 0.35 6.18 0.31
32 INT66060 Regulation of Gene_expression of PKN1 1 0.23 0 0.3
33 INT185436 Gene_expression of ROCK1 5 0.52 6.85 0.29
34 INT287251 Negative_regulation of PKN1 6 0.01 1.86 0.25
35 INT120047 Negative_regulation of Localization of ABL2 1 0.41 0 0.23
36 INT258250 Positive_regulation of ROCK1 7 0.51 2.07 0.22
37 INT120048 Localization of ABL2 2 0.73 0.19 0.22
38 INT185443 Regulation of ROCK1 4 0.18 3.32 0.21
39 INT252745 Positive_regulation of Positive_regulation of RAF1 3 0.20 4.62 0.21
40 INT221535 Regulation of Fes 1 0.25 0.19 0.19
41 INT221549 Localization of Fes 1 0.70 0.66 0.19
42 INT221532 Positive_regulation of Fes 1 0.47 0.59 0.19
43 INT239412 Binding of ABL1 8 0.28 5.39 0.18
44 INT221268 Localization of BRCA1 7 0.63 4.83 0.18
45 INT119061 Negative_regulation of Gene_expression of BRCA1 4 0.51 0.85 0.18
46 INT233130 Regulation of PKN1 2 0.02 0.69 0.18
47 INT89689 Binding of Brca1 2 0.37 2.55 0.18
48 INT163461 Regulation of ABL1 8 0.32 5.98 0.14
49 INT287249 Localization of PKN1 3 0.03 0.78 0.14
50 INT82805 Negative_regulation of Binding of ABL2 1 0.00 0 0.14
51 INT330973 Regulation of Phosphorylation of RAF1 1 0.30 1.09 0.14
52 INT284981 Protein_catabolism of RAF1 2 0.08 1.62 0.12
53 INT221571 Negative_regulation of Fes 1 0.55 0.56 0.12
54 INT221577 Negative_regulation of Phosphorylation of Fes 1 0.40 0.37 0.12
55 INT315042 Positive_regulation of Gene_expression of RAF1 1 0.05 0.23 0.12
56 INT187590 Gene_expression of Brca1 12 0.65 4.94 0.11
57 INT208914 Regulation of Brca1 1 0.10 0.79 0.11
58 INT280585 Negative_regulation of Gene_expression of RAF1 1 0.13 1.88 0.11
59 INT221530 Negative_regulation of Binding of Fes 1 0.40 0.17 0.08
60 INT174155 Negative_regulation of Brca1 4 0.36 1.77 0.07
61 INT252703 Localization of RAF1 2 0.32 1.3 0.07
62 INT252753 Positive_regulation of Localization of RAF1 1 0.06 1.35 0.07
63 INT163462 Negative_regulation of Regulation of ABL1 1 0.11 1.17 0.06
64 INT109594 Positive_regulation of ABL1 10 0.49 7.19 0.05
65 INT224326 Binding of RAF1 3 0.13 3.11 0.05
66 INT341887 Positive_regulation of Positive_regulation of ROCK1 1 0.01 0.12 0.05
67 INT350897 Negative_regulation of Binding of ABL1 1 0.18 1.19 0.04
68 INT343555 Regulation of Gene_expression of ROCK1 1 0.15 1.02 0.04
69 INT234417 Positive_regulation of Gene_expression of ABL1 4 0.37 3.65 0.03
70 INT192237 Phosphorylation of ROCK1 2 0.19 0.39 0.03
71 INT187589 Positive_regulation of Gene_expression of Brca1 2 0.55 1.93 0.03
72 INT344009 Negative_regulation of Localization of BRCA1 1 0.30 0.18 0.03
73 INT343556 Positive_regulation of Gene_expression of ROCK1 1 0.23 1.05 0.03
74 INT221565 Regulation of Binding of Fes 1 0.42 0.05 0.03
75 INT222851 Binding of Pkn1 4 0.03 0.1 0
76 INT233129 Binding of PKN1 3 0.03 0 0
77 INT259116 Transcription of BRCA1 3 0.44 3.77 0
78 INT325167 Gene_expression of CDK6 2 0.43 0 0
79 INT212457 Phosphorylation of Brca1 2 0.51 0.96 0
80 INT292713 Phosphorylation of ABL1 2 0.44 1.04 0
81 INT327869 Positive_regulation of Pkn1 1 0.04 0.32 0
82 INT269651 Positive_regulation of Phosphorylation of ROCK1 1 0.11 0.29 0
83 INT187580 Positive_regulation of Brca1 1 0.10 1.17 0
84 INT258237 Negative_regulation of Negative_regulation of ROCK1 1 0.32 0.16 0
85 INT119064 Regulation of Gene_expression of BRCA1 1 0.53 0.05 0
86 INT350510 Localization of ABL1 1 0.40 2.51 0
87 INT269598 Regulation of Positive_regulation of PKN1 1 0.07 0 0
88 INT292711 Regulation of Gene_expression of ABL1 1 0.06 1.02 0
89 INT221567 Transcription of Fes 1 0.64 0 0
90 INT287594 Negative_regulation of Pkn1 1 0.01 0.12 0
91 INT314706 Transcription of Brca1 1 0.43 0.53 0
92 INT350521 Negative_regulation of Negative_regulation of ABL1 1 0.23 0.55 0
93 INT327859 Gene_expression of Pkn1 1 0.07 0 0
94 INT221563 Positive_regulation of Localization of Fes 1 0.47 0.05 0
95 INT156466 Regulation of Negative_regulation of ABL1 1 0.44 0.63 0
96 INT221271 Negative_regulation of Binding of BRCA1 1 0.28 0.93 0
97 INT350517 Negative_regulation of Gene_expression of ABL1 1 0.23 0.53 0
98 INT165179 Regulation of Positive_regulation of ABL1 1 0.15 0.95 0
99 INT221524 Regulation of Localization of Fes 1 0.42 0.06 0
100 INT280590 Transcription of RAF1 1 0.52 0.75 0
101 INT302260 Negative_regulation of CDK6 1 0.19 0.29 0
102 INT221523 Negative_regulation of Gene_expression of Fes 1 0.40 0 0
103 INT334189 Regulation of Binding of BRCA1 1 0.13 0.8 0
104 INT234188 Positive_regulation of Localization of BRCA1 1 0.42 0.68 0
105 INT325171 Regulation of Gene_expression of CDK6 1 0.25 0 0
106 INT269645 Negative_regulation of Positive_regulation of ROCK1 1 0.10 0 0
107 INT350512 Positive_regulation of Phosphorylation of ABL1 1 0.27 0.75 0
108 INT287254 Positive_regulation of Negative_regulation of PKN1 1 0.01 0.41 0
109 INT351489 Regulation of Transcription of ABL1 1 0.28 0.08 0
110 INT350508 Protein_catabolism of ABL1 1 0.54 0.5 0
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