GO:2000256

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Name positive regulation of male germ cell proliferation
Categary Process
Go Slim No
Go Link GO:2000256
Unique Molecular Interactions 95
Total Molecular Interactions 152
Total Single Events 856
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of male germ cell proliferation. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of male germ cell proliferation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83
2 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
3 INT176368 IL18 Positive_regulation of Gene_expression of IFNA1 1 0.16 2.53 1.35
4 INT160585 IL18 Positive_regulation of Gene_expression of OPRM1 1 0.09 0.54 1.35
5 INT203178 IL18 Positive_regulation of Gene_expression of Lts1 1 0.01 1.98 1.02
6 INT141276 Negative_regulation of Il18 Negative_regulation of Gene_expression of Hand2 1 0.25 0.8 0.92
7 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79
8 INT224580 Gene_expression of IL18 Positive_regulation of SERPINH1 1 0.00 1.34 0.7
9 INT205706 P2rx7 Regulation of Gene_expression of Il18 1 0.21 1.35 0.7
10 INT171976 Il18 Positive_regulation of Gene_expression of IFNA1 1 0.01 1.37 0.64
11 INT299004 Binding of Il18 and Il1 1 0.04 1.16 0.58
12 INT176370 IL18BP Negative_regulation of IL18 1 0.15 0.76 0.56
13 INT297311 Casp1 Positive_regulation of Il18 1 0.09 1.02 0.55
14 INT226360 IL18 Positive_regulation of Gene_expression of IL4 1 0.05 2.66 0.54
15 INT226348 IL18 Positive_regulation of Gene_expression of IL13 1 0.03 2.66 0.54
16 INT206010 Foxm1 Positive_regulation of Gene_expression of Il18 1 0.03 0.72 0.5
17 INT260836 Il18 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.48
18 INT222284 Negative_regulation of Casp1 Negative_regulation of Il18 1 0.01 0.79 0.46
19 INT224699 Il18 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
20 INT298999 Binding of Il18bp and Il18 1 0.02 0 0.45
21 INT354395 TNFSF12 Regulation of Gene_expression of IL18 1 0.47 0.79 0.45
22 INT172136 IL18 Positive_regulation of Gene_expression of IFN1@ 1 0.09 0.63 0.42
23 INT178823 TNF Regulation of Il18 1 0.18 3.28 0.41
24 INT176361 Positive_regulation of LBR Positive_regulation of Gene_expression of IL18 1 0.10 0.84 0.39
25 INT141016 Il18 Positive_regulation of Gene_expression of Ifng 1 0.39 0.27 0.39
26 INT182054 Il18 Positive_regulation of LOH19CR1 1 0.55 0.74 0.38
27 INT182052 Il18 Positive_regulation of Col7a1 1 0.03 0.74 0.38
28 INT182051 Il18 Positive_regulation of Il1 1 0.18 0.77 0.38
29 INT262824 Gene_expression of Serpinf1 Negative_regulation of Gene_expression of Il18 1 0.39 1.56 0.37
30 INT152313 Il18 Regulation of Ednrb 1 0.30 0.22 0.36
31 INT152314 Il18 Regulation of Edn1 1 0.02 0.22 0.36
32 INT176373 IL18 Regulation of FASLG 1 0.41 0.4 0.35
33 INT205704 P2rx7 Regulation of Localization of Il18 1 0.09 0.67 0.35
34 INT300729 IL18 Positive_regulation of IL13 1 0.00 0 0.33
35 INT174265 IL18 Regulation of Gene_expression of F3 1 0.00 3.21 0.33
36 INT98013 Il18 Positive_regulation of Gene_expression of IFNG 1 0.66 0.44 0.32
37 INT176362 Binding of IL18 and IL18BP 1 0.12 0.49 0.32
38 INT317835 Nlrp3 Positive_regulation of Il18 1 0.08 1.49 0.31
39 INT219151 IL18 Positive_regulation of CASP1 1 0.01 1.05 0.3
40 INT182053 Il18 Positive_regulation of TNF 1 0.06 0.63 0.29
41 INT298996 Il18 Positive_regulation of Gene_expression of Cdk5r1 1 0.03 1.65 0.29
42 INT298995 Il18 Positive_regulation of Gene_expression of Cdk5 1 0.12 1.65 0.29
43 INT299008 Il18 Positive_regulation of Transcription of Cdk5 1 0.12 1.65 0.29
44 INT299011 Il18 Positive_regulation of Transcription of Cdk5r1 1 0.03 1.65 0.29
45 INT176372 Positive_regulation of IL18 Positive_regulation of IFNA1 1 0.16 0.36 0.28
46 INT176369 IL18 Regulation of TH1L 1 0.27 0.33 0.26
47 INT299013 Il18 Regulation of Ltp 1 0.05 0.39 0.25
48 INT299003 Il18 Positive_regulation of Gene_expression of Il13 1 0.11 0.73 0.24
49 INT113419 IL10 Negative_regulation of Gene_expression of IL18 1 0.31 0.86 0.24
50 INT104553 Il18 Negative_regulation of Il18bp 1 0.26 1.09 0.23
51 INT303606 Binding of IL18 and SOAT1 1 0.05 0.52 0.22
52 INT299000 Positive_regulation of Il18 Regulation of Ltp 1 0.05 0.35 0.2
53 INT91653 Negative_regulation of CASP1 Negative_regulation of IL18 1 0.39 0.15 0.2
54 INT252788 Binding of IL12A and IL18 1 0.01 1.33 0.19
55 INT316748 IL18 Positive_regulation of Regulation of Hand2 1 0.14 1.11 0.18
56 INT159596 Binding of IL18 and IL18R1 1 0.08 0.17 0.17
57 INT298998 Il18 Positive_regulation of Cdk5 1 0.11 0.36 0.17
58 INT354400 IL18 Regulation of Gene_expression of TNFSF12 1 0.35 0.55 0.17
59 INT299001 Il18 Positive_regulation of Cdk5r1 1 0.03 0.36 0.17
60 INT331600 Il18 Regulation of IFN1@ 1 0.00 1.05 0.16
61 INT334530 Sema3a Regulation of Il18 1 0.18 1.61 0.13
62 INT354403 IL18 Regulation of TNFSF12 1 0.35 0.11 0.13
63 INT299015 Binding of FAS and Il18 1 0.38 0.83 0.11
64 INT354401 TNFSF12 Regulation of IL18 1 0.47 0 0.1
65 INT298994 Binding of Il18 and Il1f5 1 0.01 0 0.1
66 INT294431 IL18 Positive_regulation of Gene_expression of SELE 1 0.06 0.98 0.1
67 INT294430 IL18 Positive_regulation of Gene_expression of VCAM1 1 0.10 0.91 0.09
68 INT276814 IL18 Positive_regulation of Gene_expression of Hgs 1 0.05 0.09 0.09
69 INT239839 IL18 Positive_regulation of TNF 1 0.11 1.08 0.09
70 INT297317 Positive_regulation of Mthfd1 Positive_regulation of Gene_expression of Il18 1 0.07 0.79 0.08
71 INT299002 Negative_regulation of Binding of Il18bp and Il18 1 0.02 0 0.08
72 INT178821 TNF Negative_regulation of Il18 1 0.29 0.64 0.08
73 INT354402 IL18 Positive_regulation of Gene_expression of TNFSF12 1 0.39 0.55 0.08
74 INT262821 Serpinf1 Negative_regulation of Gene_expression of Il18 1 0.54 0.85 0.08
75 INT299009 Il1f5 Negative_regulation of Il18 1 0.01 0 0.07
76 INT354391 Binding of IL18 and UNK 1 0.23 0.66 0.06
77 INT354397 Positive_regulation of IL18 Regulation of Gene_expression of TNFSF12 1 0.18 0 0.05
78 INT224679 Il18 Positive_regulation of Gene_expression of Vcam1 1 0.01 0.41 0.05
79 INT194735 IL18 Positive_regulation of Positive_regulation of MAPK1 1 0.05 0 0.04
80 INT194741 IL18 Positive_regulation of Gene_expression of GADD45A 1 0.05 0 0.04
81 INT194704 IL18 Positive_regulation of GADD45A 1 0.08 0 0.04
82 INT178822 TNF Regulation of Gene_expression of Il18 1 0.18 0.47 0.03
83 INT299006 Binding of Il18 and Myd88 1 0.21 0.19 0.03
84 INT165187 Positive_regulation of Binding of CST3 and IL18 1 0.03 0.28 0
85 INT165197 Positive_regulation of Binding of IL18 and Havcr1 1 0.00 0.28 0
86 INT165195 Binding of IL18 and Havcr1 1 0.00 0.28 0
87 INT165198 Positive_regulation of Binding of IL18 and Fabp1 1 0.01 0.55 0
88 INT334538 Il18 Positive_regulation of Localization of IFN1@ 1 0.34 0.65 0
89 INT165190 Binding of IL18 and LCN2 1 0.00 0.28 0
90 INT139563 Tlr4 Positive_regulation of Localization of IL18 1 0.01 0 0
91 INT186376 IFNA1 Positive_regulation of Il18 1 0.02 0.76 0
92 INT354404 Binding of IL18 and NCR1 1 0.22 0 0
93 INT165196 Binding of IL18 and Fabp1 1 0.01 0.55 0
94 INT165189 Binding of CST3 and IL18 1 0.02 0.28 0
95 INT165188 Positive_regulation of Binding of IL18 and LCN2 1 0.00 0.28 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of male germ cell proliferation. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of male germ cell proliferation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT104551 Gene_expression of Il18 156 0.76 115.51 36.95
2 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95
3 INT87861 Gene_expression of Il18 33 0.78 30.44 18.42
4 INT104550 Positive_regulation of Il18 67 0.70 55.14 17.48
5 INT141014 Positive_regulation of Gene_expression of Il18 46 0.68 47.63 13.3
6 INT87863 Positive_regulation of IL18 40 0.69 34.08 9.53
7 INT94127 Positive_regulation of Il18 14 0.69 14 7.47
8 INT91721 Binding of IL18 21 0.48 21.17 6.56
9 INT91657 Negative_regulation of IL18 20 0.48 15.97 6.12
10 INT104547 Negative_regulation of Il18 24 0.59 17.89 6.01
11 INT124705 Binding of Il18 29 0.47 19.02 5.59
12 INT113420 Positive_regulation of Gene_expression of IL18 22 0.69 19.96 5.53
13 INT104549 Localization of Il18 16 0.78 13.01 4.64
14 INT165891 Transcription of Il18 5 0.69 7.63 4.37
15 INT35175 Localization of IL18 18 0.80 12.96 3.83
16 INT141015 Regulation of Il18 14 0.59 6.3 3.73
17 INT148151 Regulation of Il18 7 0.28 5.4 3.5
18 INT176383 Negative_regulation of Binding of IL18 1 0.35 5.91 2.91
19 INT139562 Transcription of IL18 10 0.68 6.14 2.73
20 INT222289 Localization of Il18 4 0.30 3.24 2.58
21 INT165892 Positive_regulation of Transcription of Il18 3 0.66 3.72 2.38
22 INT133567 Regulation of IL18 11 0.50 9.54 2.31
23 INT148152 Binding of Il18 4 0.46 4.44 2.19
24 INT104548 Positive_regulation of Positive_regulation of Il18 7 0.66 5.74 2.13
25 INT94128 Positive_regulation of Gene_expression of Il18 6 0.50 3.64 2.06
26 INT118305 Negative_regulation of Gene_expression of IL18 7 0.39 6.52 2.05
27 INT98888 Negative_regulation of Gene_expression of Il18 3 0.43 1.72 2.02
28 INT159598 Positive_regulation of Transcription of IL18 3 0.48 1.84 1.32
29 INT69037 Regulation of Gene_expression of IL18 4 0.43 3.29 1.31
30 INT176379 Regulation of Binding of IL18 1 0.37 2.37 1.17
31 INT35174 Positive_regulation of Localization of IL18 7 0.69 5.22 1.08
32 INT252286 Phosphorylation of Il18 2 0.79 2.22 0.86
33 INT163786 Regulation of Gene_expression of Il18 1 0.28 0.88 0.74
34 INT163788 Negative_regulation of Regulation of Il18 1 0.27 0.87 0.73
35 INT138489 Negative_regulation of Il18 1 0.02 0.48 0.7
36 INT178818 Regulation of Gene_expression of Il18 3 0.40 2.98 0.68
37 INT182050 Negative_regulation of Gene_expression of Il18 4 0.57 1.98 0.56
38 INT176384 Positive_regulation of Binding of IL18 1 0.41 0.98 0.51
39 INT252287 Positive_regulation of Phosphorylation of Il18 1 0.13 0.59 0.49
40 INT205689 Protein_catabolism of Il18 2 0.23 0.8 0.47
41 INT205684 Negative_regulation of Localization of Il18 1 0.13 0.61 0.39
42 INT91668 Positive_regulation of Negative_regulation of IL18 1 0.38 0.24 0.38
43 INT168788 Positive_regulation of Positive_regulation of Il18 1 0.16 0.73 0.38
44 INT182047 Negative_regulation of Negative_regulation of Il18 1 0.42 0.74 0.37
45 INT205688 Regulation of Localization of Il18 1 0.08 0.59 0.34
46 INT91660 Positive_regulation of Positive_regulation of IL18 1 0.41 0.25 0.31
47 INT113421 Negative_regulation of Localization of IL18 2 0.58 0.87 0.27
48 INT298985 Regulation of Regulation of Il18 1 0.26 0.32 0.22
49 INT186274 Positive_regulation of Binding of Il18 1 0.16 0 0.14
50 INT178819 Negative_regulation of Positive_regulation of Il18 1 0.38 0.58 0.13
51 INT306736 Negative_regulation of Transcription of IL18 2 0.38 0.31 0.11
52 INT239842 Negative_regulation of Positive_regulation of IL18 1 0.20 1.1 0.08
53 INT298987 Positive_regulation of Negative_regulation of Il18 1 0.45 0 0.07
54 INT159600 Regulation of Transcription of IL18 2 0.43 0.07 0.06
55 INT298984 Negative_regulation of Binding of Il18 1 0.41 0.1 0.04
56 INT137341 Positive_regulation of Transcription of Il18 1 0.47 0.09 0
57 INT316745 Phosphorylation of IL18 1 0.70 0.79 0
58 INT137342 Transcription of Il18 1 0.53 0.09 0
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