GO:2000311

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Name regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
Categary Process
Go Slim No
Go Link GO:2000311
Unique Molecular Interactions 49
Total Molecular Interactions 91
Total Single Events 159
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT296477 Binding of Cacng2 and Dlg4 1 0.04 0.22 0.42
2 INT296450 Cacng2 Regulation of Gria2 1 0.13 0.24 0.26
3 INT346745 Binding of Cacng2 and Grip2 1 0.01 0 0.25
4 INT296470 Binding of Cacng2 and Myo18a 1 0.00 0.22 0.24
5 INT296467 Binding of Cacng2 and Gria1 1 0.12 0.25 0.23
6 INT296464 Binding of Cacng2 and Tinagl1 1 0.06 0.25 0.23
7 INT296474 Binding of Cacng2 and Gria2 1 0.18 0.26 0.23
8 INT103359 Binding of Mapk3 and Mink1 1 0.09 0.17 0.22
9 INT103358 Binding of Mapk1 and Mink1 1 0.07 0.17 0.22
10 INT296469 Gene_expression of Cacng2 Positive_regulation of Gria2 1 0.15 0 0.16
11 INT296461 Gene_expression of Cacng2 Positive_regulation of Rbm39 1 0.00 0 0.16
12 INT296468 Cacng2 Regulation of Regulation of Gria2 1 0.10 0 0.11
13 INT303179 Binding of Dlgap1 and Shank1 1 0.22 0.31 0.1
14 INT303180 Trim3 Negative_regulation of Shank1 1 0.40 0 0.09
15 INT303176 Gene_expression of Trim3 Positive_regulation of Protein_catabolism of Shank1 1 0.44 0 0.07
16 INT244022 Binding of Nrxn1 and Nlgn4l 1 0.00 0.21 0.07
17 INT354963 Binding of Cttn and Shank1 1 0.12 0 0.04
18 INT354971 Binding of HOMER1 and Shank1 1 0.01 0 0.04
19 INT303170 Gene_expression of Trim3 Negative_regulation of Shank1 1 0.40 0.12 0.04
20 INT272603 Binding of Dlg4 and Nlgn2 1 0.23 0 0.03
21 INT272594 Binding of Dlg4 and Shank1 1 0.20 0 0.03
22 INT303159 Trim3 Negative_regulation of Gene_expression of Shank1 1 0.40 0 0
23 INT346742 Binding of Cacng2 and Dlg4 1 0.03 0 0
24 INT303185 Binding of Shank1 and Trim3 1 0.35 0 0
25 INT346746 Binding of Cacng2 and Gria2 1 0.21 0.18 0
26 INT303161 Gene_expression of Trim3 Positive_regulation of Shank1 1 0.44 0 0
27 INT303169 Trim3 Regulation of Gene_expression of Shank1 1 0.42 0 0
28 INT303163 Shank1 Positive_regulation of Trim3 1 0.47 0 0
29 INT303173 Negative_regulation of Trim3 Negative_regulation of Shank1 1 0.40 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT128413 Positive_regulation of Shank1 2 0.70 0.61 1.16
2 INT128411 Regulation of Shank1 2 0.45 0.81 0.95
3 INT272575 Binding of Cacng2 3 0.36 0.54 0.58
4 INT103354 Positive_regulation of Binding of Mink1 1 0.11 0.34 0.44
5 INT303211 Gene_expression of Shank1 1 0.64 0.48 0.4
6 INT103355 Binding of Mink1 1 0.08 0.17 0.22
7 INT170513 Gene_expression of Cacng2 3 0.65 0.06 0.18
8 INT296433 Positive_regulation of Gene_expression of Cacng2 1 0.18 0 0.16
9 INT303216 Protein_catabolism of Shank1 1 0.83 0 0.15
10 INT243912 Gene_expression of Nlgn2 2 0.37 0.22 0.12
11 INT303217 Binding of Shank1 1 0.36 0 0.11
12 INT303233 Negative_regulation of Gene_expression of Shank1 1 0.49 0.07 0.1
13 INT251222 Localization of Nlgn2 1 0.20 0 0.1
14 INT303212 Positive_regulation of Protein_catabolism of Shank1 1 0.42 0 0.08
15 INT243988 Binding of Nrxn1 1 0.01 0.21 0.07
16 INT272574 Gene_expression of Shank1 2 0.61 0.22 0.06
17 INT346730 Positive_regulation of Cacng2 1 0.49 0 0.06
18 INT303195 Positive_regulation of Gene_expression of Shank1 1 0.42 0.08 0.06
19 INT243932 Gene_expression of Nrxn1 1 0.02 0.28 0.06
20 INT303204 Negative_regulation of Shank1 1 0.42 0.11 0.04
21 INT346727 Regulation of Cacng2 1 0.26 0 0.03
22 INT303227 Regulation of Negative_regulation of Shank1 1 0.26 0 0
23 INT303202 Negative_regulation of Protein_catabolism of Shank1 1 0.49 0 0
24 INT303209 Positive_regulation of Positive_regulation of Shank1 1 0.34 0 0
25 INT303193 Localization of Shank1 1 0.62 0.19 0
26 INT303199 Regulation of Gene_expression of Shank1 1 0.23 0 0
27 INT346728 Localization of Cacng2 1 0.73 0 0
28 INT354939 Positive_regulation of Gene_expression of Shank1 1 0.45 0.14 0
29 INT303232 Regulation of Protein_catabolism of Shank1 1 0.38 0 0
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