GO:2000353

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Name positive regulation of endothelial cell apoptosis
Categary Process
Go Slim No
Go Link GO:2000353
Unique Molecular Interactions 116
Total Molecular Interactions 262
Total Single Events 1605
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of endothelial cell apoptosis. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of endothelial cell apoptosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62
2 INT140935 Binding of Cd40lg and Cd40 1 0.30 6.34 5.61
3 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01
4 INT83425 Binding of CD40LG and IGHG3 11 0.21 4.56 2.09
5 INT122428 Binding of Ighm and Prkci 1 0.00 0 1.66
6 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
7 INT122430 Negative_regulation of Binding of Ighm and Prkci 1 0.00 0 1.36
8 INT153589 Binding of PRKCI and Oprm1 1 0.06 0 1.17
9 INT122432 Prkci Regulation of Negative_regulation of Oprd1 1 0.01 0 1.06
10 INT131853 CD40 Negative_regulation of Gene_expression of CD40LG 1 0.09 1.54 1.05
11 INT122429 Prkci Regulation of Gene_expression of Ighm 1 0.00 0 1.02
12 INT122431 Prkci Negative_regulation of Negative_regulation of Ighm 1 0.00 0 1.02
13 INT122433 Prkci Negative_regulation of Ighm 1 0.00 0 1.02
14 INT140936 Binding of Cd40lg and Ean5 1 0.07 1.03 0.98
15 INT140934 Binding of Cd40 and Ean5 1 0.09 1.03 0.98
16 INT160413 Tat Positive_regulation of Gene_expression of Cd40lg 1 0.50 0.98 0.86
17 INT125234 Positive_regulation of Binding of BCR and CD40LG 1 0.31 0.76 0.86
18 INT125233 Binding of BCR and CD40LG 1 0.23 0.75 0.85
19 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72
20 INT92998 Positive_regulation of SFTPA1 Positive_regulation of Localization of CD40 1 0.15 0.34 0.61
21 INT83424 Binding of CD40LG and ADIPOQ 2 0.13 1 0.59
22 INT83426 ADIPOQ Negative_regulation of Binding of CD40LG 2 0.21 1 0.59
23 INT92999 Binding of CD40 and VCAM1 1 0.39 0.33 0.57
24 INT190702 CD40 Positive_regulation of Gene_expression of F3 1 0.00 1.4 0.55
25 INT249600 IFNA1 Positive_regulation of Gene_expression of Cd40 1 0.49 1.13 0.52
26 INT116926 Cpox Regulation of AKR1C3 1 0.01 0.28 0.45
27 INT189846 Binding of Cd40 and Churc1 1 0.01 0.73 0.41
28 INT122169 AKR1C3 Regulation of PPARG 1 0.45 0.26 0.33
29 INT156087 Binding of AKR1C3 and Akr1c1 1 0.05 0.31 0.3
30 INT156083 Binding of AKR1C2 and AKR1C3 1 0.05 0.31 0.3
31 INT156084 Binding of PTGS2 and AKR1C3 1 0.02 0.31 0.3
32 INT156082 Binding of PTGS1 and AKR1C3 1 0.01 0.31 0.3
33 INT191503 CD40LG Regulation of Gene_expression of F3 1 0.01 0.99 0.27
34 INT343906 Hmgb1 Positive_regulation of Gene_expression of Cd40 1 0.05 0.41 0.24
35 INT188699 Binding of Cd40lg and Eae1 1 0.05 1.51 0.24
36 INT188696 Binding of Cd40 and Eae1 1 0.05 1.57 0.21
37 INT238001 Cxcl10 Positive_regulation of Gene_expression of Cd40 1 0.17 0.91 0.21
38 INT350016 Binding of CD40LG and ARID1B 1 0.01 3.26 0.21
39 INT311987 Binding of Cd40 and Negative_regulation of Regulation of Hand1 1 0.28 0.27 0.21
40 INT322733 CD40LG Positive_regulation of Gene_expression of CD40 1 0.08 0.62 0.18
41 INT322734 Binding of CD40LG and Positive_regulation of CD40 1 0.07 0.62 0.18
42 INT336751 Binding of Selp and Cd40 1 0.03 2.49 0.18
43 INT337180 CD40 Positive_regulation of Gene_expression of CD83 1 0.17 1.07 0.17
44 INT111802 Binding of CD40LG and TFPI 1 0.14 0.62 0.16
45 INT85445 NUBPL Negative_regulation of Gene_expression of CD40LG 1 0.01 0.31 0.16
46 INT310257 Tlr4 Positive_regulation of Gene_expression of Cd40 1 0.13 0.06 0.15
47 INT188697 Il6 Positive_regulation of Cd40 1 0.05 0.18 0.14
48 INT249598 Stat1 Positive_regulation of Gene_expression of Cd40 1 0.41 0.46 0.14
49 INT194576 Binding of ACLY and CD40LG 1 0.07 0.07 0.14
50 INT272776 CD40 Positive_regulation of Gene_expression of IGHG3 1 0.01 0.18 0.14
51 INT324128 Binding of Cd4 and Cd40 2 0.29 0.3 0.13
52 INT331564 Binding of Apcs and Cd40 1 0.12 0.74 0.13
53 INT324082 CD40 Positive_regulation of MAPK9 1 0.21 0.64 0.13
54 INT298476 CD40LG Positive_regulation of HLA-DRB1 1 0.01 0.33 0.12
55 INT298471 CD40LG Positive_regulation of CD80 1 0.04 0.33 0.12
56 INT330380 CD40 Regulation of Gene_expression of IFNA1 1 0.17 0.78 0.1
57 INT189848 IFN1@ Positive_regulation of Gene_expression of Cd40 1 0.69 0 0.09
58 INT249601 IFNA1 Negative_regulation of Gene_expression of Cd40 1 0.42 0.51 0.09
59 INT240770 Binding of CD40LG and F13A1 1 0.02 1.4 0.09
60 INT252344 Binding of Cd40 and Mthfd1 2 0.16 0.34 0.08
61 INT202505 Binding of Cd40lg and Positive_regulation of Positive_regulation of Nfasc 1 0.09 0.45 0.08
62 INT277807 CD40LG Regulation of CD40 1 0.21 0.17 0.08
63 INT231504 Binding of Tlr4 and Cd40 1 0.09 0.18 0.08
64 INT337166 PTGER2 Positive_regulation of Gene_expression of CD40 1 0.02 0.77 0.07
65 INT234381 Binding of CD40 and PPARA 1 0.19 1.39 0.07
66 INT331561 Binding of Cd4 and Cd40lg 1 0.28 0.06 0.06
67 INT220903 Regulation of Binding of Crp and Cd40 1 0.05 0.37 0.05
68 INT220906 Binding of Crp and Cd40 1 0.04 0.37 0.05
69 INT284559 Gopc Positive_regulation of Cd40 1 0.19 0.23 0.05
70 INT342886 Binding of C3 and CD40 1 0.02 0.66 0.05
71 INT328667 Binding of CD40LG and CSF2 1 0.16 0.59 0.05
72 INT234380 Negative_regulation of Binding of CD40 and CD40LG 1 0.16 1.4 0.04
73 INT227774 Negative_regulation of Binding of Cd40 and Cd40lg 1 0.31 0.29 0.03
74 INT211873 TP53 Positive_regulation of Transcription of CD40 1 0.03 1.44 0.03
75 INT288007 Binding of CD28 and CD40 1 0.05 0.51 0.03
76 INT211872 TP53 Positive_regulation of CD40 1 0.03 1.44 0.03
77 INT252339 Binding of Cd40 and Positive_regulation of Mthfd1 1 0.04 0.19 0
78 INT349016 Negative_regulation of Binding of Cd80 and Cd40 1 0.25 0 0
79 INT344266 Binding of APOH and CD40LG 1 0.04 0.31 0
80 INT220901 Regulation of Binding of Saa1 and Cd40 1 0.04 0.36 0
81 INT252331 Binding of Cd40lg and Mthfd1 1 0.03 0.1 0
82 INT170586 CD40 Negative_regulation of Positive_regulation of RELA 1 0.12 0.24 0
83 INT277809 Binding of CD4 and CD40LG 1 0.15 0 0
84 INT286653 Binding of CD40LG and OLR1 1 0.08 0.41 0
85 INT276390 Positive_regulation of CD40 Positive_regulation of Gene_expression of Pdcd1 1 0.01 1.06 0
86 INT276378 CD40 Positive_regulation of Gene_expression of Pdcd1 1 0.01 1.06 0
87 INT290160 Atp6v1e1 Positive_regulation of Cd40 1 0.24 0.5 0
88 INT101943 Binding of CD40LG and HSD11B1 1 0.08 0.23 0
89 INT252341 Cd40 Positive_regulation of Gene_expression of Cd80 1 0.12 0.1 0
90 INT308702 Binding of AQP4 and CD40LG 1 0.10 0 0
91 INT336574 Binding of CD40LG and HCRTR1 1 0.05 0.1 0
92 INT83446 CD40LG Positive_regulation of Localization of CCL2 1 0.00 0.17 0
93 INT248298 Binding of Cd40 and Rf 1 0.08 0 0
94 INT314970 Binding of Cd40 and Lbr 1 0.03 0.07 0
95 INT252334 Positive_regulation of Binding of Cd40 and Cd40lg 1 0.11 0.1 0
96 INT194926 Binding of CD40LG and Positive_regulation of BCR 1 0.04 0.39 0
97 INT284553 Adc Positive_regulation of Gene_expression of Cd40 1 0.18 0.35 0
98 INT288008 Binding of CD40 and LRRC23 1 0.02 0.45 0
99 INT220900 Binding of C4bp and Cd40 1 0.21 0.72 0
100 INT194927 Binding of CD40LG and Positive_regulation of CD79B 1 0.01 0.4 0
101 INT220908 Binding of Saa1 and Cd40 1 0.04 0.36 0
102 INT352086 Binding of CD40 and ADAM11 1 0.08 0.77 0
103 INT147062 LAMC2 Negative_regulation of CD40LG 1 0.47 0 0
104 INT349017 Binding of Cd80 and Cd40 1 0.22 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of endothelial cell apoptosis. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of endothelial cell apoptosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23
2 INT96156 Gene_expression of Cd40 144 0.77 56.95 21.7
3 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46
4 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86
5 INT133156 Binding of Cd40 77 0.48 45.92 13.77
6 INT24816 Binding of CD40LG 68 0.47 45.48 11.56
7 INT85966 Gene_expression of Cd40lg 50 0.73 30.9 9.11
8 INT93003 Binding of CD40 28 0.47 20.25 7.13
9 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7
10 INT83451 Positive_regulation of Gene_expression of CD40LG 26 0.60 22.81 6.25
11 INT142607 Positive_regulation of Gene_expression of Cd40 41 0.62 13.85 5.51
12 INT45753 Localization of CD40LG 45 0.79 32.31 5.28
13 INT101594 Positive_regulation of Cd40 36 0.69 16.14 4.56
14 INT85965 Binding of Cd40lg 26 0.45 16.76 4.52
15 INT5148 Regulation of CD40LG 25 0.44 21.58 4.05
16 INT108086 Negative_regulation of AKR1C3 17 0.58 7.7 3.99
17 INT140932 Binding of Cd40 1 0.44 4.19 3.6
18 INT140933 Binding of Cd40lg 1 0.38 4.2 3.6
19 INT93915 Positive_regulation of Gene_expression of CD40 14 0.44 12.45 3.35
20 INT140931 Gene_expression of Cd40lg 5 0.61 5.2 3.33
21 INT85971 Positive_regulation of Gene_expression of Cd40lg 14 0.66 7.61 3.29
22 INT125237 Negative_regulation of Gene_expression of CD40LG 16 0.54 9.9 3.27
23 INT142606 Regulation of Gene_expression of Cd40 13 0.56 6.15 3.27
24 INT85970 Positive_regulation of Cd40lg 21 0.53 8.51 3.16
25 INT93913 Positive_regulation of CD40 21 0.58 23.47 3.1
26 INT140929 Gene_expression of Cd40 9 0.72 8.76 2.88
27 INT78146 Gene_expression of AKR1C3 24 0.77 5.71 2.77
28 INT96151 Negative_regulation of Gene_expression of Cd40 20 0.58 6.06 2.58
29 INT122424 Gene_expression of Prkci 1 0.58 0 2.56
30 INT248297 Negative_regulation of Cd40 14 0.58 8.96 2.34
31 INT122423 Negative_regulation of Gene_expression of Prkci 1 0.43 0 2.04
32 INT51840 Positive_regulation of Localization of CD40LG 8 0.69 9.59 1.58
33 INT93001 Localization of CD40 4 0.78 1.97 1.45
34 INT188691 Negative_regulation of Binding of Cd40 3 0.42 2.49 1.31
35 INT189836 Regulation of Cd40 10 0.40 3.02 1.1
36 INT188667 Localization of Cd40lg 5 0.57 3.29 1.07
37 INT188664 Negative_regulation of Cd40lg 7 0.33 3.99 1.04
38 INT122421 Phosphorylation of Prkci 1 0.47 0 1.02
39 INT140928 Negative_regulation of Gene_expression of Cd40lg 1 0.46 1.09 1.01
40 INT140930 Positive_regulation of Gene_expression of Cd40 4 0.64 3.26 0.99
41 INT160406 Transcription of Cd40lg 2 0.52 1.52 0.83
42 INT170603 Negative_regulation of Gene_expression of CD40 5 0.32 2.18 0.78
43 INT108085 Positive_regulation of Gene_expression of AKR1C3 2 0.53 0.58 0.75
44 INT250281 Positive_regulation of Positive_regulation of CD40LG 3 0.23 3.19 0.73
45 INT153565 Gene_expression of PRKCI 1 0.75 0 0.72
46 INT5211 Localization of Cd40 6 0.78 1.75 0.71
47 INT85969 Regulation of Gene_expression of Cd40lg 2 0.43 1.96 0.69
48 INT285262 Regulation of Cd40lg 3 0.34 1.48 0.66
49 INT178201 Negative_regulation of Binding of Cd40lg 2 0.33 2.92 0.64
50 INT97130 Negative_regulation of CD40 5 0.35 1.96 0.63
51 INT153568 Binding of PRKCI 1 0.36 0 0.6
52 INT130373 Regulation of Gene_expression of CD40LG 3 0.60 1.87 0.59
53 INT122420 Regulation of Prkci 1 0.44 0 0.58
54 INT269970 Positive_regulation of Positive_regulation of Cd40 2 0.50 1.79 0.57
55 INT116925 Binding of AKR1C3 2 0.36 0.75 0.56
56 INT83435 Negative_regulation of Binding of CD40LG 2 0.39 0.96 0.55
57 INT236370 Positive_regulation of Phosphorylation of CD40LG 1 0.37 0.59 0.55
58 INT188663 Regulation of Binding of Cd40 1 0.41 0.95 0.55
59 INT83436 Positive_regulation of Binding of CD40LG 3 0.33 0.85 0.49
60 INT311966 Positive_regulation of Cd40 2 0.50 1.46 0.49
61 INT130391 Positive_regulation of AKR1C3 4 0.50 1.7 0.47
62 INT105408 Negative_regulation of Gene_expression of AKR1C3 1 0.23 0.56 0.45
63 INT238502 Regulation of CD40 6 0.28 3.7 0.44
64 INT216992 Regulation of Binding of CD40 1 0.13 0.06 0.41
65 INT188680 Positive_regulation of Binding of Cd40 1 0.46 1.33 0.32
66 INT151274 Negative_regulation of Gene_expression of Cd40lg 3 0.32 2.16 0.3
67 INT153836 Phosphorylation of CD40LG 2 0.79 0.47 0.28
68 INT176333 Transcription of Cd40 1 0.52 0.8 0.28
69 INT5213 Regulation of Localization of Cd40 1 0.26 0 0.27
70 INT217002 Positive_regulation of Localization of CD40 1 0.14 0 0.26
71 INT311985 Regulation of Positive_regulation of Cd40 1 0.45 0.64 0.24
72 INT285263 Positive_regulation of Negative_regulation of Cd40lg 1 0.26 0.34 0.19
73 INT76125 Transcription of CD40LG 5 0.55 2.66 0.18
74 INT219192 Positive_regulation of Regulation of CD40LG 2 0.43 2.9 0.17
75 INT252316 Regulation of Regulation of Cd40 2 0.24 0.71 0.15
76 INT238504 Positive_regulation of Positive_regulation of CD40 2 0.36 3.03 0.15
77 INT234680 Localization of Cd40 1 0.18 0.16 0.14
78 INT332303 Localization of Cd40lg 1 0.00 0.26 0.14
79 INT78144 Transcription of AKR1C3 4 0.72 1.21 0.13
80 INT285264 Regulation of Localization of Cd40lg 1 0.25 0.42 0.13
81 INT219164 Regulation of Positive_regulation of CD40LG 1 0.04 1.51 0.13
82 INT257930 Regulation of Binding of Cd40lg 1 0.13 1.14 0.12
83 INT170592 Regulation of Gene_expression of CD40 4 0.17 0 0.11
84 INT240780 Negative_regulation of Localization of CD40LG 2 0.24 0.72 0.1
85 INT252306 Positive_regulation of Binding of Cd40lg 1 0.22 0.55 0.1
86 INT288014 Negative_regulation of Positive_regulation of CD40 1 0.17 0.63 0.09
87 INT311981 Regulation of Protein_catabolism of Cd40 1 0.45 0.31 0.07
88 INT311983 Protein_catabolism of Cd40 1 0.88 0.31 0.07
89 INT143828 Regulation of AKR1C3 1 0.06 1.32 0.07
90 INT275162 Negative_regulation of Gene_expression of Cd40 1 0.14 1.23 0.06
91 INT209184 Regulation of PRKCI 1 0.02 0.06 0.06
92 INT285261 Regulation of Positive_regulation of Cd40lg 1 0.15 0.11 0.05
93 INT211878 Transcription of CD40 2 0.35 2.01 0.03
94 INT337233 Positive_regulation of Binding of CD40 1 0.26 0.6 0.03
95 INT178540 Regulation of Gene_expression of AKR1C3 1 0.59 0.32 0
96 INT284542 Negative_regulation of Positive_regulation of Cd40 1 0.27 0.28 0
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