GO:2000379

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Name positive regulation of reactive oxygen species metabolic process
Categary Process
Go Slim No
Go Link GO:2000379
Unique Molecular Interactions 1099
Total Molecular Interactions 1494
Total Single Events 10790
Pain Genes Associated 47

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of reactive oxygen species metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of reactive oxygen species metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
3 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
4 INT314205 Ngf Positive_regulation of Phosphorylation of Mapk14 1 0.43 1.24 2.3
5 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
6 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
7 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 0.34 0.85 1.84
8 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
9 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
10 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
11 INT314214 Mapk14 Positive_regulation of Ngf 1 0.43 1.97 1.56
12 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
13 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
14 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
15 INT314213 Mapk14 Positive_regulation of Agtrap 1 0.04 1.15 1.34
16 INT300864 Ngf Positive_regulation of Mapk14 2 0.60 1.38 1.32
17 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
18 INT314209 Ngf Positive_regulation of Binding of Mapk14 1 0.43 1.48 1.27
19 INT69279 Regulation of Binding of TSPO and Gabrg1 1 0.00 2.05 1.26
20 INT139724 PROC Positive_regulation of MAPK14 1 0.00 1.57 1.25
21 INT99695 Binding of Tspo and Insrr 1 0.02 0.52 1.25
22 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
23 INT314198 Mapk14 Positive_regulation of Gene_expression of Trpv1 1 0.48 1.09 1.24
24 INT314212 Mapk14 Positive_regulation of Gene_expression of Agtrap 1 0.06 1.09 1.24
25 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
26 INT328742 Il1 Positive_regulation of Mapk14 1 0.01 1.4 1.2
27 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18
28 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16
29 INT314206 Mapk14 Positive_regulation of Pax3 1 0.08 0.67 1.15
30 INT190771 Gene_expression of Il4 Negative_regulation of Gene_expression of Mapk14 1 0.15 1.14 1.13
31 INT190770 Il4 Negative_regulation of Gene_expression of Mapk14 1 0.20 1.14 1.13
32 INT59606 Binding of Tspo and Penk 1 0.04 0 1.12
33 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11
34 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
35 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
36 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
37 INT283934 Phax Negative_regulation of Positive_regulation of Mapk14 1 0.03 2.06 1.09
38 INT150794 ZNF398 Positive_regulation of Localization of THBS1 1 0.09 1.02 1.07
39 INT107938 POMC Positive_regulation of Gene_expression of TGFBR2 1 0.42 1.09 1.07
40 INT150789 THBS3 Negative_regulation of THBS1 1 0.18 1.01 1.06
41 INT292531 Il10 Negative_regulation of Positive_regulation of Mapk14 1 0.15 1.13 1.06
42 INT154846 Negative_regulation of Mapk14 Negative_regulation of Positive_regulation of Trpv1 1 0.23 0.07 1.05
43 INT352456 Dusp1 Negative_regulation of Mapk14 1 0.03 1.31 1.03
44 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
45 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
46 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
47 INT283932 Positive_regulation of Mapk14 Regulation of Gene_expression of Trpv1 1 0.14 1.28 0.99
48 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98
49 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
50 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
51 INT308169 Negative_regulation of Mapk14 Negative_regulation of Ltp 1 0.01 0.79 0.95
52 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
53 INT145853 Casp1 Positive_regulation of Mapk14 1 0.02 0.68 0.93
54 INT107001 F2 Positive_regulation of PAR1 4 0.05 2.15 0.92
55 INT318461 Nnat Positive_regulation of Mapk14 1 0.05 0.97 0.92
56 INT138602 Negative_regulation of BCL2L2 Positive_regulation of F2 1 0.00 0.67 0.92
57 INT352465 Dusp1 Negative_regulation of Gene_expression of Mapk14 1 0.03 1.09 0.92
58 INT138601 BCL2L2 Positive_regulation of F2 1 0.00 0.66 0.91
59 INT34457 AGT Positive_regulation of POMC 1 0.01 0 0.91
60 INT352444 Dusp1 Negative_regulation of Phosphorylation of Mapk14 1 0.03 1.09 0.91
61 INT147474 Nfe2l2 Positive_regulation of Hmox1 1 0.43 0.38 0.9
62 INT92404 PSRC1 Regulation of CDKN1A 1 0.33 0.66 0.89
63 INT310348 Binding of Tspo and Gabrd 1 0.00 0.43 0.88
64 INT314207 Ngf Negative_regulation of Phosphorylation of Mapk14 1 0.33 0.4 0.88
65 INT209928 IL1B Positive_regulation of MAPK14 2 0.15 1.69 0.87
66 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
67 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
68 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
69 INT288201 Mapk14 Positive_regulation of Cish 1 0.03 0.06 0.82
70 INT128590 Mapk14 Regulation of Nav1 1 0.21 0.25 0.82
71 INT107937 POMC Regulation of Gene_expression of TGFBR2 1 0.28 0.82 0.81
72 INT34458 AGT Negative_regulation of PENK 1 0.00 0 0.81
73 INT168648 Positive_regulation of Cx3cr1 Positive_regulation of Phosphorylation of Mapk14 1 0.35 1.51 0.8
74 INT222024 Mapk8 Regulation of Mapk14 2 0.17 0.83 0.79
75 INT168647 Cx3cr1 Positive_regulation of Phosphorylation of Mapk14 1 0.52 1.51 0.79
76 INT196577 Negative_regulation of Mapk14 Negative_regulation of Il6 1 0.13 0.45 0.78
77 INT196574 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il6 1 0.13 0.45 0.78
78 INT196575 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1a 1 0.04 0.44 0.77
79 INT346234 MAP2K6 Positive_regulation of MAPK14 1 0.44 1.65 0.77
80 INT146780 Positive_regulation of Fgfr1 Positive_regulation of Mapk14 1 0.34 0.95 0.77
81 INT262577 Localization of Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.05 0.92 0.75
82 INT128815 Mapk14 Regulation of Gene_expression of Nos2 1 0.21 0.46 0.74
83 INT106999 F2 Positive_regulation of PAR4 3 0.06 1.83 0.72
84 INT106992 F2 Positive_regulation of PARD3 3 0.05 1.83 0.72
85 INT89009 Lep Positive_regulation of Cck 2 0.67 0.43 0.69
86 INT164783 Positive_regulation of Mapk14 Regulation of Gene_expression of Cx3cr1 1 0.19 0.81 0.68
87 INT155457 Tnfrsf1a Positive_regulation of Mapk14 1 0.20 1.17 0.67
88 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
89 INT314199 Mapk14 Regulation of Tnf 1 0.26 0.71 0.67
90 INT150338 Binding of F2 and F2R 1 0.11 0.4 0.67
91 INT148139 Phosphorylation of Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.46 0.98 0.66
92 INT154766 Nox1 Positive_regulation of Localization of Prkce 1 0.47 0.45 0.66
93 INT148138 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.64 0.98 0.66
94 INT166299 Binding of Mapk14 and Gpbar1 1 0.13 0.64 0.65
95 INT209854 IL4 Positive_regulation of Gene_expression of CD36 1 0.51 1.2 0.65
96 INT166302 Negative_regulation of Binding of Mapk14 and Gpbar1 1 0.12 0.64 0.65
97 INT207111 F2 Positive_regulation of Pawr 2 0.07 1.38 0.64
98 INT288202 Negative_regulation of Cd14 Positive_regulation of Positive_regulation of Mapk14 1 0.09 1.08 0.64
99 INT113780 AGT Positive_regulation of Positive_regulation of Nfkb1 1 0.00 1.25 0.64
100 INT69280 Negative_regulation of Binding of TSPO and Gabrg1 1 0.00 1.03 0.63
101 INT165047 Mapk14 Positive_regulation of Gene_expression of Tnf 1 0.73 0.8 0.63
102 INT223155 Binding of Mapk14 and Stat4 1 0.36 0.84 0.63
103 INT148137 Tnf Positive_regulation of Positive_regulation of Mapk14 1 0.46 1 0.63
104 INT69278 Binding of TSPO and Gabrg1 1 0.00 1.01 0.62
105 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.82 0.62
106 INT166398 CDKN1B Regulation of Gene_expression of CDKN1A 1 0.46 0.83 0.61
107 INT166399 CDKN1A Regulation of Gene_expression of CDKN1B 1 0.46 0.83 0.61
108 INT166395 CDKN1A Regulation of Gene_expression of IFI27 1 0.32 0.83 0.61
109 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
110 INT128811 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Casp1 1 0.06 0.35 0.61
111 INT219280 Mapk14 Positive_regulation of Pla2g2a 1 0.33 0.46 0.61
112 INT166392 IFI27 Regulation of Gene_expression of CDKN1A 1 0.32 0.83 0.61
113 INT308175 Negative_regulation of Mapk14 Negative_regulation of Localization of TNF 1 0.03 0.89 0.61
114 INT314197 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.48 1.16 0.61
115 INT219282 Mapk14 Positive_regulation of Pla2g1b 1 0.18 0.46 0.61
116 INT92403 PSRC1 Regulation of Positive_regulation of CDKN1A 1 0.33 0.45 0.6
117 INT223158 Mapk3 Regulation of Gene_expression of Mapk14 1 0.48 1.33 0.59
118 INT314208 Trap1 Positive_regulation of Mapk14 1 0.10 0.66 0.57
119 INT110032 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il12a 1 0.36 0 0.57
120 INT349083 Binding of Lep and Rtn1 1 0.09 1.68 0.57
121 INT278694 TNF Positive_regulation of MAPK14 1 0.03 0.79 0.56
122 INT96089 Binding of F2 and Pf4 1 0.00 1.31 0.56
123 INT96098 Binding of PPBP and F2 1 0.00 1.31 0.56
124 INT196585 Mapk14 Regulation of TNF 1 0.02 0.36 0.55
125 INT328744 TNF Regulation of Positive_regulation of Mapk14 1 0.02 0.81 0.55
126 INT161251 Ptgs2 Regulation of Mapk14 1 0.16 0.82 0.54
127 INT34459 AGT Negative_regulation of MBTPS1 1 0.01 0 0.54
128 INT161250 Trib3 Regulation of Mapk14 1 0.04 0.81 0.54
129 INT132438 Binding of AGT and OXTR 1 0.08 1.03 0.53
130 INT150791 THBS1 Negative_regulation of TIMP2 1 0.17 0.5 0.52
131 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
132 INT150796 ZNF398 Positive_regulation of THBS1 1 0.06 0.5 0.52
133 INT150785 THBS1 Negative_regulation of MMP2 1 0.10 0.5 0.52
134 INT171906 MAPK1 Positive_regulation of Gene_expression of MAPK14 1 0.08 1.55 0.52
135 INT119546 Nfe2l2 Regulation of Gene_expression of Fos 1 0.48 0.94 0.52
136 INT213809 F2 Positive_regulation of F2rl3 2 0.12 0.61 0.5
137 INT313376 Cnr1 Positive_regulation of Phosphorylation of Mapk14 1 0.20 0.38 0.5
138 INT104960 Ephb1 Regulation of Positive_regulation of Mapk14 1 0.15 0.42 0.5
139 INT313375 Cnr2 Positive_regulation of Phosphorylation of Mapk14 1 0.18 0.39 0.5
140 INT19296 AGT Positive_regulation of Localization of AVP 1 0.38 0 0.5
141 INT104961 Mapk14 Regulation of Positive_regulation of Ephb1 1 0.15 0.42 0.5
142 INT21315 AGT Positive_regulation of Npy 1 0.03 0.15 0.5
143 INT84515 IRF6 Positive_regulation of Gene_expression of F2 1 0.02 0.15 0.49
144 INT84520 Gene_expression of F2 Positive_regulation of F13A1 1 0.03 0.16 0.49
145 INT57391 Binding of Tspo and Oprl1 1 0.18 0.16 0.49
146 INT110031 Positive_regulation of Adra2c Positive_regulation of Mapk14 1 0.25 0 0.48
147 INT110030 Adra2c Positive_regulation of Mapk14 1 0.25 0 0.48
148 INT110034 Negative_regulation of Adra2c Positive_regulation of Mapk14 1 0.23 0 0.48
149 INT131504 Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.14 0.2 0.47
150 INT118396 Nfe2l2 Positive_regulation of Gene_expression of Cars 1 0.05 0.26 0.47
151 INT131507 Ngf Positive_regulation of Mapk14 1 0.13 0.2 0.47
152 INT265646 Binding of Mapk1 and Mapk14 1 0.01 1.53 0.46
153 INT341622 Binding of F2 and CTRC 1 0.06 1.22 0.46
154 INT173295 F2 Positive_regulation of OR1S1 1 0.01 0.15 0.46
155 INT254225 Mapk14 Positive_regulation of Mapk8 1 0.02 0.87 0.46
156 INT254216 Mapk14 Positive_regulation of Mapk1 1 0.02 0.87 0.46
157 INT342633 ACE Regulation of Gene_expression of AGT 1 0.01 0.14 0.46
158 INT254222 Mapk1 Positive_regulation of Mapk14 1 0.02 0.86 0.46
159 INT116926 Cpox Regulation of AKR1C3 1 0.01 0.28 0.45
160 INT319554 Sgk1 Regulation of Cdkn1a 1 0.26 0.09 0.45
161 INT165677 NFE2L2 Negative_regulation of Positive_regulation of HMOX1 1 0.40 0.32 0.44
162 INT313378 Trib3 Regulation of Phosphorylation of Mapk14 1 0.01 0.37 0.44
163 INT114341 Agt Positive_regulation of AGT 3 0.01 1.15 0.43
164 INT345288 AGT Positive_regulation of Localization of CCL2 1 0.01 1.5 0.43
165 INT278964 MAPK14 Negative_regulation of Localization of EPHB2 1 0.15 0.47 0.43
166 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
167 INT165678 NFE2L2 Negative_regulation of HMOX1 1 0.40 0.31 0.43
168 INT345291 AGT Positive_regulation of CCL2 1 0.01 1.39 0.43
169 INT264479 Il1a Positive_regulation of Gene_expression of Mapk14 1 0.02 0 0.43
170 INT124088 Rab38 Negative_regulation of Mapk14 1 0.00 0.89 0.42
171 INT331799 IL8 Negative_regulation of Mapk14 1 0.01 1.6 0.42
172 INT131506 Rac1 Regulation of Positive_regulation of Mapk14 1 0.19 0.39 0.42
173 INT244280 Binding of Tspo and Ptz1a 1 0.02 0.49 0.41
174 INT162043 F2 Positive_regulation of Gene_expression of OSM 1 0.44 1.13 0.41
175 INT319313 Socs4 Positive_regulation of Mapk14 1 0.02 0.68 0.41
176 INT95402 Mapk14 Regulation of Positive_regulation of Trib3 1 0.06 0.19 0.41
177 INT162041 F2 Positive_regulation of Positive_regulation of FOS 1 0.13 1.14 0.41
178 INT75489 Binding of SGCG and Tgfbr2 1 0.23 0.83 0.41
179 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
180 INT83171 Cck Regulation of Lep 1 0.30 0.09 0.4
181 INT209858 TNF Regulation of Transcription of CD36 1 0.27 0 0.4
182 INT338044 F2 Positive_regulation of Pard3 1 0.08 0.38 0.4
183 INT56876 Regulation of Binding of Cd36 and Gtpbp4 1 0.00 0 0.4
184 INT97395 Lep Positive_regulation of Stat3 1 0.67 0.42 0.4
185 INT182489 Gene_expression of AGTR2 Positive_regulation of Gene_expression of AGTR1 1 0.26 0.92 0.4
186 INT56875 Binding of Cd36 and Gtpbp4 1 0.00 0 0.4
187 INT191493 Binding of AGTR1 and NLRP3 2 0.03 2.35 0.39
188 INT152238 Mapk14 Positive_regulation of Localization of Tlr4 1 0.29 0.13 0.39
189 INT147473 Nfe2l2 Positive_regulation of Gene_expression of Hmox1 1 0.74 0.49 0.39
190 INT152241 Mapk14 Positive_regulation of Localization of Nfkb1 1 0.25 0.13 0.39
191 INT185530 Binding of AGT and EDNRA 1 0.00 0.31 0.38
192 INT130930 Egr1 Negative_regulation of Positive_regulation of Thbs1 1 0.58 0.64 0.38
193 INT264482 Il1a Positive_regulation of Phosphorylation of Mapk14 1 0.02 0 0.37
194 INT198652 F2 Positive_regulation of Gene_expression of CD36 1 0.03 1.32 0.37
195 INT264481 Il1a Positive_regulation of Mapk14 1 0.02 0 0.37
196 INT278970 MAPK14 Positive_regulation of Gene_expression of IL8 1 0.11 0.66 0.37
197 INT353391 Binding of DRD4 and GRB2 1 0.37 0.62 0.37
198 INT52632 Binding of TSPO and CCK 1 0.15 0.53 0.37
199 INT278938 MAPK14 Positive_regulation of Gene_expression of PRKCA 1 0.05 0.65 0.37
200 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of reactive oxygen species metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of reactive oxygen species metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61
2 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46
3 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51
4 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79
5 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59
6 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32
7 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42
8 INT97702 Positive_regulation of Phosphorylation of Mapk14 69 0.69 49.21 36.81
9 INT84825 Gene_expression of CD36 121 0.78 43.73 33.23
10 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08
11 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
12 INT106272 Positive_regulation of Positive_regulation of Mapk14 39 0.70 32.08 24.71
13 INT86534 Positive_regulation of MAPK14 81 0.62 57.81 23.62
14 INT99069 Positive_regulation of Gene_expression of Mapk14 42 0.53 29.84 23.16
15 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
16 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73
17 INT69322 Negative_regulation of MAPK14 70 0.54 42.92 22.71
18 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91
19 INT171924 Gene_expression of MAPK14 60 0.65 54.38 21.68
20 INT125411 Negative_regulation of Phosphorylation of Mapk14 31 0.57 18.55 19.98
21 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3
22 INT111531 Negative_regulation of Phosphorylation of Mapk14 37 0.50 20 17.68
23 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92
24 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
25 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
26 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
27 INT96911 Positive_regulation of Phosphorylation of Mapk14 46 0.70 43.03 15.15
28 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74
29 INT142621 Positive_regulation of Gene_expression of CD36 38 0.70 15.18 13.4
30 INT104954 Negative_regulation of Positive_regulation of Mapk14 29 0.58 17.71 13.31
31 INT3962 Regulation of AGT 50 0.62 20.96 13.01
32 INT110025 Positive_regulation of Positive_regulation of Mapk14 39 0.63 20.67 12.71
33 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63
34 INT73641 Regulation of Lep 45 0.62 26.2 12.59
35 INT117113 Regulation of Mapk14 28 0.45 16.71 11.99
36 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64
37 INT118906 Regulation of Mapk14 21 0.44 17.95 11.63
38 INT398 Localization of AGT 45 0.78 16.97 11.54
39 INT82079 Positive_regulation of Lep 79 0.70 40 11.07
40 INT8065 Binding of AGT 54 0.48 20.54 10.85
41 INT4498 Gene_expression of F2 83 0.65 57.4 10.8
42 INT103923 Negative_regulation of Positive_regulation of Mapk14 23 0.53 13.95 10.64
43 INT118390 Positive_regulation of Nfe2l2 82 0.70 20.41 10.61
44 INT110178 Phosphorylation of MAPK14 40 0.68 19.38 10.37
45 INT18088 Binding of Tspo 26 0.48 9.12 10.2
46 INT424 Positive_regulation of TSPO 34 0.61 15.04 10.02
47 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
48 INT62269 Gene_expression of Cdkn1a 60 0.73 35.78 9.84
49 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69
50 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38
51 INT82082 Localization of Lep 63 0.81 26.41 8.56
52 INT209866 Regulation of Gene_expression of CD36 27 0.60 10.04 8.42
53 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
54 INT39170 Gene_expression of TSPO 76 0.78 24.11 8.05
55 INT2271 Gene_expression of F2 51 0.76 30.21 7.97
56 INT159750 Negative_regulation of Gene_expression of Mapk14 15 0.40 10.88 7.81
57 INT6335 Binding of TSPO 39 0.44 10.88 7.66
58 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51
59 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
60 INT83006 Gene_expression of AGTR1 59 0.75 54.46 7.27
61 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
62 INT128695 Regulation of Gene_expression of Mapk14 14 0.44 11.49 7.14
63 INT717 Regulation of F2 29 0.61 17.46 6.99
64 INT1038 Negative_regulation of F2 26 0.58 15.12 6.75
65 INT117142 Gene_expression of Thbs1 58 0.72 45.02 6.51
66 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
67 INT14258 Regulation of TSPO 32 0.60 10.16 6.24
68 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14
69 INT128587 Localization of Mapk14 15 0.81 8.41 6.1
70 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
71 INT118388 Localization of Nfe2l2 40 0.81 9.59 5.89
72 INT104330 Negative_regulation of CDKN1A 57 0.58 39.93 5.88
73 INT62270 Positive_regulation of Gene_expression of Cdkn1a 30 0.47 18.73 5.69
74 INT22839 Gene_expression of F2 31 0.74 15.53 5.56
75 INT164656 Negative_regulation of Gene_expression of CD36 24 0.57 6.51 5.39
76 INT102891 Positive_regulation of AGTR1 31 0.67 30.57 5.29
77 INT60585 Regulation of TP53 59 0.59 54.55 5.21
78 INT176524 Binding of Mapk14 19 0.43 12.54 5.21
79 INT107386 Negative_regulation of AGTR1 37 0.55 35.94 5.15
80 INT20650 Positive_regulation of F2 26 0.69 15.49 5.08
81 INT126047 Regulation of Phosphorylation of Mapk14 7 0.60 5.05 5.03
82 INT16051 Regulation of Tspo 6 0.45 2.81 4.95
83 INT160055 Localization of CDKN1A 15 0.78 12.56 4.83
84 INT171472 Binding of Mapk14 10 0.36 6.79 4.83
85 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
86 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
87 INT29809 Gene_expression of Tspo 8 0.75 4.12 4.54
88 INT97391 Binding of Lep 18 0.48 8.97 4.47
89 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
90 INT7841 Gene_expression of Tspo 10 0.75 7.63 4.45
91 INT9842 Binding of F2 36 0.47 22.79 4.42
92 INT3332 Protein_catabolism of AGT 23 0.87 3.17 4.39
93 INT74531 Regulation of PDGFB 14 0.26 7.57 4.38
94 INT6881 Binding of Tspo 12 0.46 5.03 4.38
95 INT117920 Regulation of MAPK14 14 0.38 8.75 4.31
96 INT110024 Negative_regulation of Gene_expression of Mapk14 19 0.42 7.83 4.21
97 INT119544 Gene_expression of Nfe2l2 50 0.77 19.32 4.19
98 INT117921 Positive_regulation of Positive_regulation of MAPK14 9 0.44 9.93 4.18
99 INT131782 Regulation of Positive_regulation of Mapk14 7 0.43 2.68 4.02
100 INT108086 Negative_regulation of AKR1C3 17 0.58 7.7 3.99
101 INT110021 Positive_regulation of Gene_expression of Mapk14 29 0.46 19.06 3.86
102 INT75485 Gene_expression of Tgfbr2 10 0.57 10.98 3.76
103 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
104 INT84427 Positive_regulation of Gene_expression of TSPO 15 0.64 5.05 3.58
105 INT70897 Positive_regulation of Gene_expression of PDGFB 15 0.57 13.04 3.52
106 INT82077 Positive_regulation of Gene_expression of Lep 32 0.70 17.9 3.5
107 INT26702 Transcription of CD36 17 0.70 3.56 3.49
108 INT36716 Positive_regulation of Gene_expression of Tspo 4 0.68 3.48 3.49
109 INT28802 Binding of F2 15 0.47 8.8 3.47
110 INT63506 Localization of F2 21 0.77 7.53 3.41
111 INT70895 Localization of PDGFB 20 0.52 8.98 3.4
112 INT4545 Negative_regulation of Nox1 15 0.53 10.08 3.4
113 INT82796 Regulation of CDKN1A 22 0.53 9.83 3.33
114 INT118393 Positive_regulation of Localization of Nfe2l2 9 0.70 2.82 3.3
115 INT62268 Positive_regulation of Cdkn1a 33 0.67 14.12 3.26
116 INT48902 Gene_expression of ACE2 22 0.78 17.91 3.24
117 INT70885 Gene_expression of Pdgfb 48 0.67 42.27 3.19
118 INT25745 Regulation of Tspo 6 0.45 0.25 3.1
119 INT91173 Gene_expression of Pdgfrb 33 0.65 32.55 3.09
120 INT75505 Regulation of Gene_expression of CDKN1A 24 0.60 12.24 3.07
121 INT8103 Binding of TP53 46 0.44 40.2 2.96
122 INT173179 Binding of MAPK14 13 0.29 4.51 2.92
123 INT155453 Protein_catabolism of Mapk14 6 0.36 4.24 2.85
124 INT75499 Positive_regulation of Positive_regulation of CDKN1A 12 0.60 7.28 2.84
125 INT118394 Positive_regulation of Positive_regulation of Nfe2l2 13 0.70 1.4 2.81
126 INT96901 Regulation of Negative_regulation of Mapk14 3 0.45 4.07 2.79
127 INT78146 Gene_expression of AKR1C3 24 0.77 5.71 2.77
128 INT95105 Gene_expression of TGFBR2 15 0.64 16.36 2.74
129 INT14447 Localization of F2 20 0.79 12.77 2.67
130 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
131 INT74527 Positive_regulation of PDGFB 14 0.38 13.31 2.54
132 INT71933 Positive_regulation of Gene_expression of F2 19 0.56 14.24 2.53
133 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
134 INT137135 Gene_expression of THBS1 28 0.75 11.55 2.45
135 INT17857 Negative_regulation of Gene_expression of AGT 25 0.46 21.16 2.45
136 INT137908 Phosphorylation of Pdgfrb 14 0.81 8.44 2.45
137 INT110179 Negative_regulation of Phosphorylation of MAPK14 11 0.36 5.25 2.38
138 INT103487 Positive_regulation of Positive_regulation of Lep 9 0.67 4.08 2.38
139 INT55952 Transcription of TP53 16 0.61 12.14 2.36
140 INT198662 Positive_regulation of CD36 14 0.68 7.73 2.36
141 INT27988 Negative_regulation of Positive_regulation of AGT 11 0.42 5.71 2.27
142 INT163545 Gene_expression of PDGFRB 39 0.78 25.5 2.2
143 INT63505 Negative_regulation of F2 18 0.57 7.4 2.2
144 INT82081 Regulation of Gene_expression of Lep 11 0.53 7.78 2.12
145 INT26706 Positive_regulation of Transcription of CD36 8 0.68 3.32 2.12
146 INT74131 Positive_regulation of Tspo 7 0.50 0.92 2.11
147 INT173647 Positive_regulation of Gene_expression of MAPK14 15 0.39 7.54 2.05
148 INT83392 Transcription of Lep 6 0.54 5.07 2.04
149 INT154651 Negative_regulation of Nfe2l2 19 0.59 10.48 2.01
150 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
151 INT94285 Negative_regulation of CD36 10 0.43 6.61 1.98
152 INT130364 Positive_regulation of Thbs1 7 0.62 7.73 1.97
153 INT199084 Gene_expression of Cd36 31 0.53 16.94 1.94
154 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
155 INT26311 Negative_regulation of ACE2 8 0.59 16.35 1.94
156 INT137906 Positive_regulation of Phosphorylation of Pdgfrb 6 0.50 2.55 1.94
157 INT144020 Positive_regulation of Pdgfrb 30 0.69 24.8 1.92
158 INT65855 Localization of TP53 18 0.76 17.08 1.89
159 INT14257 Localization of TSPO 9 0.73 1.48 1.87
160 INT60337 Positive_regulation of THBS1 8 0.46 4.69 1.83
161 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
162 INT182505 Positive_regulation of Gene_expression of AGTR1 12 0.65 13.18 1.77
163 INT118907 Negative_regulation of Negative_regulation of Mapk14 2 0.57 2.09 1.77
164 INT82083 Negative_regulation of Gene_expression of Lep 12 0.56 8.07 1.75
165 INT19576 Negative_regulation of Tspo 3 0.42 1.02 1.75
166 INT119540 Binding of Nfe2l2 29 0.48 6.34 1.74
167 INT152894 Regulation of Positive_regulation of Mapk14 9 0.45 6.01 1.74
168 INT101816 Localization of NFE2L2 17 0.77 6.91 1.69
169 INT168686 Transcription of Mapk14 6 0.52 2.96 1.67
170 INT173173 Regulation of Positive_regulation of MAPK14 6 0.38 2.59 1.64
171 INT104331 Negative_regulation of Gene_expression of CDKN1A 24 0.57 13.68 1.63
172 INT6391 Positive_regulation of Tspo 2 0.50 0.93 1.63
173 INT88667 Negative_regulation of Gene_expression of F2 11 0.41 5.53 1.62
174 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
175 INT182297 Positive_regulation of Phosphorylation of MAPK14 7 0.42 3.36 1.53
176 INT22836 Regulation of F2 9 0.59 2.3 1.49
177 INT182514 Binding of AGTR1 18 0.47 13.35 1.48
178 INT74528 Negative_regulation of PDGFB 11 0.40 10.34 1.48
179 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
180 INT154763 Gene_expression of Nox1 3 0.67 1.83 1.48
181 INT12035 Regulation of F2 21 0.45 12.66 1.47
182 INT74530 Transcription of PDGFB 7 0.65 4.56 1.47
183 INT154764 Localization of Nox1 1 0.65 1.07 1.47
184 INT173654 Localization of MAPK14 12 0.62 3.16 1.43
185 INT147471 Positive_regulation of Gene_expression of Nfe2l2 10 0.57 4.18 1.43
186 INT34768 Negative_regulation of Negative_regulation of AGT 10 0.25 2.79 1.42
187 INT39444 Negative_regulation of Positive_regulation of F2 7 0.59 5.82 1.42
188 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
189 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
190 INT172953 Binding of Trp53 33 0.37 20.76 1.41
191 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
192 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
193 INT182511 Regulation of AGTR1 7 0.44 8.25 1.4
194 INT8067 Negative_regulation of Binding of AGT 12 0.25 10.33 1.39
195 INT145221 Binding of Tp53 10 0.37 8.59 1.37
196 INT44529 Positive_regulation of Pdgfb 11 0.43 7.98 1.36
197 INT73938 Gene_expression of Cd36 20 0.76 12.27 1.35
198 INT39634 Regulation of Gene_expression of F2 4 0.22 1.72 1.31
199 INT215380 Positive_regulation of Gene_expression of Cd36 12 0.47 8.51 1.3
200 INT39443 Positive_regulation of Positive_regulation of F2 6 0.70 4.31 1.3
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