GO:2000463

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Name positive regulation of excitatory postsynaptic membrane potential
Categary Process
Go Slim No
Go Link GO:2000463
Unique Molecular Interactions 44
Total Molecular Interactions 84
Total Single Events 194
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of excitatory postsynaptic membrane potential. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of excitatory postsynaptic membrane potential. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
2 INT167767 Prkcz Positive_regulation of Phosphorylation of Sigmar1 1 0.04 0.23 0.9
3 INT167766 Prkcz Positive_regulation of Positive_regulation of Sigmar1 1 0.04 0.23 0.9
4 INT167770 Sigmar1 Positive_regulation of Prkcz 1 0.04 0.34 0.77
5 INT167768 Regulation of Sigmar1 Positive_regulation of Prkcz 1 0.02 0.34 0.77
6 INT110476 EDN1 Positive_regulation of Localization of PRKCZ 1 0.25 0.07 0.46
7 INT354968 Shank3 Positive_regulation of Gene_expression of Gria2 1 0.05 0 0.15
8 INT303179 Binding of Dlgap1 and Shank1 1 0.22 0.31 0.1
9 INT303180 Trim3 Negative_regulation of Shank1 1 0.40 0 0.09
10 INT354962 Gene_expression of Shank3 Positive_regulation of Gusb 1 0.10 0.45 0.08
11 INT303176 Gene_expression of Trim3 Positive_regulation of Protein_catabolism of Shank1 1 0.44 0 0.07
12 INT244022 Binding of Nrxn1 and Nlgn4l 1 0.00 0.21 0.07
13 INT354963 Binding of Cttn and Shank1 1 0.12 0 0.04
14 INT354971 Binding of HOMER1 and Shank1 1 0.01 0 0.04
15 INT303170 Gene_expression of Trim3 Negative_regulation of Shank1 1 0.40 0.12 0.04
16 INT272603 Binding of Dlg4 and Nlgn2 1 0.23 0 0.03
17 INT272594 Binding of Dlg4 and Shank1 1 0.20 0 0.03
18 INT303159 Trim3 Negative_regulation of Gene_expression of Shank1 1 0.40 0 0
19 INT303185 Binding of Shank1 and Trim3 1 0.35 0 0
20 INT303161 Gene_expression of Trim3 Positive_regulation of Shank1 1 0.44 0 0
21 INT303169 Trim3 Regulation of Gene_expression of Shank1 1 0.42 0 0
22 INT303163 Shank1 Positive_regulation of Trim3 1 0.47 0 0
23 INT303173 Negative_regulation of Trim3 Negative_regulation of Shank1 1 0.40 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of excitatory postsynaptic membrane potential. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of excitatory postsynaptic membrane potential. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT118151 Positive_regulation of Prkcz 5 0.12 2.35 6.41
2 INT118156 Binding of Prkcz 2 0.08 2.68 2.89
3 INT109059 Gene_expression of PRKCZ 2 0.65 0.64 1.87
4 INT118149 Positive_regulation of Binding of Prkcz 1 0.09 0.58 1.54
5 INT118150 Positive_regulation of Positive_regulation of Prkcz 1 0.08 0.49 1.42
6 INT128413 Positive_regulation of Shank1 2 0.70 0.61 1.16
7 INT128411 Regulation of Shank1 2 0.45 0.81 0.95
8 INT167763 Negative_regulation of Prkcz 1 0.04 0.32 0.88
9 INT109060 Regulation of Gene_expression of PRKCZ 1 0.03 0 0.83
10 INT354944 Negative_regulation of Shank3 1 0.59 1.18 0.59
11 INT110477 Positive_regulation of Localization of PRKCZ 1 0.20 0.07 0.45
12 INT354955 Gene_expression of Shank3 1 0.78 3.23 0.45
13 INT110479 Localization of PRKCZ 1 0.35 0.07 0.43
14 INT303211 Gene_expression of Shank1 1 0.64 0.48 0.4
15 INT110478 Regulation of PRKCZ 1 0.20 0.1 0.37
16 INT354948 Regulation of Shank3 1 0.45 0.69 0.26
17 INT303216 Protein_catabolism of Shank1 1 0.83 0 0.15
18 INT243912 Gene_expression of Nlgn2 2 0.37 0.22 0.12
19 INT303217 Binding of Shank1 1 0.36 0 0.11
20 INT303233 Negative_regulation of Gene_expression of Shank1 1 0.49 0.07 0.1
21 INT251222 Localization of Nlgn2 1 0.20 0 0.1
22 INT354949 Positive_regulation of Gene_expression of Shank3 1 0.70 0.45 0.08
23 INT354958 Localization of Shank3 1 0.80 0.4 0.08
24 INT303212 Positive_regulation of Protein_catabolism of Shank1 1 0.42 0 0.08
25 INT243988 Binding of Nrxn1 1 0.01 0.21 0.07
26 INT272574 Gene_expression of Shank1 2 0.61 0.22 0.06
27 INT303195 Positive_regulation of Gene_expression of Shank1 1 0.42 0.08 0.06
28 INT354959 Regulation of Gene_expression of Shank3 1 0.27 1.11 0.06
29 INT243932 Gene_expression of Nrxn1 1 0.02 0.28 0.06
30 INT303204 Negative_regulation of Shank1 1 0.42 0.11 0.04
31 INT303227 Regulation of Negative_regulation of Shank1 1 0.26 0 0
32 INT354953 Negative_regulation of Gene_expression of Shank3 1 0.59 0.36 0
33 INT354960 Binding of Shank3 1 0.32 0 0
34 INT303202 Negative_regulation of Protein_catabolism of Shank1 1 0.49 0 0
35 INT303209 Positive_regulation of Positive_regulation of Shank1 1 0.34 0 0
36 INT303193 Localization of Shank1 1 0.62 0.19 0
37 INT303199 Regulation of Gene_expression of Shank1 1 0.23 0 0
38 INT354939 Positive_regulation of Gene_expression of Shank1 1 0.45 0.14 0
39 INT303232 Regulation of Protein_catabolism of Shank1 1 0.38 0 0
40 INT354946 Positive_regulation of Shank3 1 0.50 0 0
41 INT354938 Transcription of Shank3 1 0.69 0 0
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