GO:2000474

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Name regulation of opioid receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:2000474
Unique Molecular Interactions 47
Total Molecular Interactions 81
Total Single Events 509
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of opioid receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for regulation of opioid receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT317511 Ppp1r9b Regulation of Oprm1 3 0.27 0.33 3.85
2 INT302118 Binding of Oprm1 and Ppp1r9b 2 0.24 0.26 3.45
3 INT259231 Binding of Oprm1 and Ppp1r9b 1 0.01 0 2.67
4 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48
5 INT259211 Binding of Ppp1r9b and Flna 1 0.06 0 1.33
6 INT302119 Positive_regulation of Binding of Oprm1 and Ppp1r9b 1 0.02 0 0.77
7 INT354249 Binding of Mtap6 and Ppp1r9b 1 0.24 0.07 0.67
8 INT313435 Syp Regulation of Th 1 0.43 1.6 0.64
9 INT147273 Bdnf Regulation of Syp 1 0.24 0 0.56
10 INT141242 Binding of SYP and DNLZ 1 0.29 1.74 0.41
11 INT313455 Binding of Ppp2ca and Syp 1 0.45 0.68 0.4
12 INT313446 Syp Regulation of Ppp2ca 1 0.58 0.62 0.26
13 INT316945 Positive_regulation of Ltp Positive_regulation of Positive_regulation of Syp 1 0.01 0 0.21
14 INT316946 Ltp Positive_regulation of Positive_regulation of Syp 1 0.01 0 0.19
15 INT313439 Syp Negative_regulation of Th 1 0.30 0.14 0.13
16 INT313466 Syp Negative_regulation of Siglec1 1 0.05 0.24 0.12
17 INT342405 AAVS1 Positive_regulation of Syp 1 0.05 0.19 0.11
18 INT313454 Negative_regulation of Syp Negative_regulation of Th 1 0.30 0.14 0.1
19 INT313430 Syp Positive_regulation of Ppp2ca 1 0.66 0.08 0.09
20 INT313442 Th Regulation of Phosphorylation of Syp 1 0.32 0 0.08
21 INT251231 Binding of Syp and Slc17a6 1 0.04 0 0.08
22 INT313447 Ppp2ca Regulation of Phosphorylation of Syp 1 0.43 0 0.08
23 INT313459 Gene_expression of Syp Negative_regulation of Th 1 0.30 0.49 0.08
24 INT342404 Binding of AAVS1 and Syp 1 0.04 0.07 0.08
25 INT212080 Eno2 Regulation of Localization of SYP 1 0.03 0.51 0.07
26 INT212079 SYP Regulation of Localization of Afp 1 0.10 0.52 0.07
27 INT212063 CHGA Regulation of Localization of SYP 1 0.49 0.51 0.07
28 INT212064 ENO2 Regulation of Localization of SYP 1 0.49 0.51 0.07
29 INT212069 SYP Regulation of Localization of EPHB6 1 0.49 0.52 0.07
30 INT212062 SYP Regulation of Localization of AFP 1 0.49 0.52 0.07
31 INT313450 Th Regulation of Syp 1 0.32 0.6 0.06
32 INT313463 Ppp2ca Regulation of Syp 1 0.43 0.6 0.06
33 INT342403 Regulation of Binding of AAVS1 and Syp 1 0.04 0 0.04
34 INT313462 Syp Positive_regulation of Binding of Ppp2ca 1 0.47 0 0.04
35 INT238086 Binding of C2 and Syp 1 0.00 0 0.03
36 INT313448 Gene_expression of Syp Positive_regulation of Th 1 0.28 0 0.03
37 INT313468 Negative_regulation of Syp Regulation of Th 1 0.30 0.3 0.03
38 INT313451 Gene_expression of Syp Negative_regulation of Mapk1 1 0.09 0 0.03
39 INT313443 Syp Positive_regulation of Binding of Th 1 0.35 0.31 0
40 INT313429 Syp Regulation of Phosphorylation of Siglec1 1 0.04 0.57 0
41 INT278934 Binding of Syp and Meta 1 0.01 0 0
42 INT313465 Syp Regulation of Regulation of Ppp2ca 1 0.26 0.56 0
43 INT278931 Positive_regulation of Binding of Syp and Meta 1 0.01 0 0
44 INT313452 Phosphorylation of Siglec1 Regulation of Syp 1 0.06 0.1 0
45 INT313428 Binding of Syp and Th 1 0.25 0.31 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of opioid receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in regulation of opioid receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT62564 Gene_expression of Syp 40 0.76 15.56 17
2 INT106477 Positive_regulation of Syp 21 0.68 8.69 10.3
3 INT24891 Gene_expression of SYP 55 0.75 45.76 7.53
4 INT115677 Positive_regulation of Gene_expression of Syp 15 0.63 4.69 6.25
5 INT160853 Gene_expression of Syp 87 0.72 20.06 5.31
6 INT121759 Localization of Syp 8 0.73 1.78 2.84
7 INT99961 Positive_regulation of SYP 13 0.67 15.13 2.79
8 INT106476 Regulation of Gene_expression of Syp 3 0.60 2.32 2.3
9 INT264600 Negative_regulation of Gene_expression of Syp 8 0.31 2.88 2.23
10 INT24890 Localization of SYP 5 0.73 2.22 2.23
11 INT110242 Regulation of Syp 4 0.32 1.72 1.96
12 INT245663 Phosphorylation of Syp 2 0.76 7.4 1.88
13 INT100135 Negative_regulation of Syp 6 0.57 2.76 1.74
14 INT245670 Positive_regulation of Gene_expression of Syp 37 0.65 7.34 1.25
15 INT354243 Negative_regulation of Ppp1r9b 1 0.28 0.28 1.12
16 INT136284 Binding of Syp 3 0.36 0.73 1.08
17 INT185969 Regulation of Syp 5 0.57 2.58 0.92
18 INT185973 Negative_regulation of Syp 16 0.54 2.83 0.87
19 INT287686 Positive_regulation of Positive_regulation of Syp 2 0.36 1.08 0.86
20 INT82374 Binding of SYP 13 0.36 13.69 0.85
21 INT316932 Regulation of Positive_regulation of Syp 1 0.33 0.72 0.76
22 INT234494 Positive_regulation of Syp 12 0.65 2.47 0.69
23 INT218815 Localization of Ppp1r9b 1 0.47 1.2 0.65
24 INT251227 Binding of Syp 2 0.45 2.42 0.55
25 INT100136 Negative_regulation of Negative_regulation of Syp 1 0.42 0.62 0.55
26 INT167897 Gene_expression of Ppp1r9b 3 0.58 0.32 0.48
27 INT167898 Negative_regulation of Gene_expression of Ppp1r9b 1 0.42 0.32 0.48
28 INT218809 Positive_regulation of Ppp1r9b 1 0.24 1.21 0.45
29 INT132885 Regulation of SYP 4 0.44 3.92 0.44
30 INT316937 Negative_regulation of Positive_regulation of Syp 1 0.27 0.15 0.41
31 INT159232 Negative_regulation of SYP 4 0.41 4.45 0.38
32 INT217376 Regulation of Gene_expression of Syp 2 0.25 0.89 0.38
33 INT185964 Negative_regulation of Gene_expression of Syp 8 0.54 2.33 0.35
34 INT313412 Localization of Syp 3 0.70 0.39 0.34
35 INT217371 Negative_regulation of Negative_regulation of Syp 2 0.11 1.16 0.29
36 INT200901 Negative_regulation of Localization of Syp 1 0.41 0 0.22
37 INT150744 Negative_regulation of Gene_expression of SYP 4 0.41 2.35 0.2
38 INT316934 Positive_regulation of Localization of Syp 1 0.34 0 0.19
39 INT324124 Positive_regulation of Gene_expression of SYP 1 0.13 0.07 0.14
40 INT167900 Regulation of Ppp1r9b 1 0.26 0.07 0.13
41 INT313414 Negative_regulation of Phosphorylation of Syp 1 0.35 0.15 0.13
42 INT238076 Regulation of Regulation of Syp 1 0.03 0 0.1
43 INT313419 Positive_regulation of Phosphorylation of Syp 1 0.47 0 0.07
44 INT313424 Regulation of Phosphorylation of Syp 1 0.42 0.36 0.07
45 INT135380 Transcription of SYP 1 0.67 1.11 0.07
46 INT354602 Binding of Ppp1r9b 1 0.11 0 0
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