GO:2000737

From wiki-pain
Jump to: navigation, search
Name negative regulation of stem cell differentiation
Categary Process
Go Slim No
Go Link GO:2000737
Unique Molecular Interactions 98
Total Molecular Interactions 144
Total Single Events 636
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of stem cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of stem cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
2 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
3 INT148381 UFM1 Positive_regulation of JAG1 1 0.00 1.13 0.63
4 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
5 INT148377 PDP1 Positive_regulation of NOTCH1 1 0.44 0.64 0.44
6 INT148378 CP Positive_regulation of NOTCH1 1 0.11 0.64 0.44
7 INT297545 Pou3f3 Regulation of Hes1 1 0.05 0.41 0.2
8 INT297544 Pou3f3 Regulation of Notch1 1 0.06 0.41 0.2
9 INT316052 Notch1 Regulation of Binding of Cd8a 1 0.01 0.86 0.15
10 INT316053 Notch1 Regulation of Binding of Cd4 1 0.02 0.86 0.15
11 INT316050 Binding of Notch1 and Regulation of Binding of Cd8a 1 0.01 0.86 0.15
12 INT316051 Binding of Notch1 and Regulation of Binding of Cd4 1 0.02 0.86 0.15
13 INT297546 Neurod1 Regulation of Notch1 1 0.05 0.2 0.1
14 INT297548 Neurod1 Regulation of Hes1 1 0.05 0.2 0.1
15 INT278217 Binding of Ciita and Notch1 1 0.41 0.22 0.09
16 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
17 INT351422 Mfng Negative_regulation of Jag1 1 0.06 1.29 0.07
18 INT297246 Binding of Notch1 and Ncstn 1 0.04 0.32 0.07
19 INT327871 Binding of Notch1 and Postn 1 0.38 1.42 0.07
20 INT297244 Regulation of Binding of Notch1 and Ncstn 1 0.05 0.32 0.07
21 INT189557 Binding of NOTCH1 and ROBO4 1 0.01 0.22 0.06
22 INT303393 Binding of Jag1 and Tceb2 1 0.03 0.29 0.04
23 INT349314 Binding of Notch1 and Notch3 1 0.11 0.67 0.04
24 INT332483 Binding of JAG1 and SGPP2 1 0.21 0.23 0.04
25 INT303389 Binding of Jag1 and Cul5 1 0.20 0.29 0.04
26 INT347165 Binding of NOTCH1 and PAX5 1 0.05 0.86 0.03
27 INT327876 Postn Regulation of Gene_expression of Notch1 1 0.56 0.92 0.03
28 INT347163 NOTCH1 Positive_regulation of MSC 1 0.03 0.85 0.03
29 INT347164 NOTCH1 Negative_regulation of Gene_expression of EBF1 1 0.03 0.85 0.03
30 INT258529 Binding of JAG1 and NOTCH1 3 0.06 2.44 0
31 INT258528 Binding of NOTCH1 and DLL1 2 0.07 1.6 0
32 INT291330 Binding of ENO1 and NOTCH1 1 0.03 1.33 0
33 INT193946 Binding of Notch1 and Positive_regulation of Psen1 1 0.03 0.06 0
34 INT303397 Binding of Jag1 and Gopc 1 0.13 0 0
35 INT327870 Postn Positive_regulation of Gene_expression of Notch1 1 0.37 0.57 0
36 INT297245 Prnp Positive_regulation of Notch1 1 0.21 0.73 0
37 INT264735 Binding of Hes1 and Mir199b 1 0.08 0.93 0
38 INT327873 Postn Regulation of Notch1 1 0.41 0 0
39 INT303398 Jag1 Positive_regulation of Protein_catabolism of Myh3 1 0.52 0 0
40 INT264738 Mir199b Regulation of Gene_expression of Hes1 1 0.08 0.89 0
41 INT291329 Binding of NOTCH1 and CERS1 1 0.06 1.42 0
42 INT356083 Binding of App and Notch1 1 0.02 0.2 0
43 INT303405 Binding of NPAT and Jag1 1 0.39 0 0
44 INT193949 Alph1 Positive_regulation of Notch1 1 0.01 0.08 0
45 INT227218 Binding of JAG1 and CD8A 1 0.05 0.5 0
46 INT264736 Hes1 Regulation of Notch2 1 0.20 0.13 0
47 INT193950 Alph1 Positive_regulation of Positive_regulation of Notch1 1 0.01 0.07 0
48 INT303404 Binding of TCAP and Jag1 1 0.39 0 0
49 INT197316 Hes1 Regulation of Atoh1 1 0.01 0.14 0
50 INT193948 Binding of Psen1 and Notch1 1 0.02 0 0
51 INT264727 Binding of Notch1 and Mir199b 1 0.00 0.86 0
52 INT197304 Ahr Regulation of Hes1 1 0.06 0.17 0
53 INT264731 Gene_expression of Hes1 Negative_regulation of Positive_regulation of Musd1 1 0.00 0.18 0
54 INT303399 Binding of Jag1 and Myh3 1 0.50 0.85 0
55 INT197315 Hes5 Regulation of Atoh1 1 0.00 0.14 0
56 INT264728 Mir199b Regulation of Notch1 1 0.01 0.85 0
57 INT303391 Binding of Jag1 and Tceb1 1 0.44 0 0
58 INT285770 Binding of NOTCH1 and Das 1 0.00 1.14 0
59 INT197314 Hes5 Regulation of Ascl1 1 0.00 0.14 0
60 INT264726 Binding of Notch1 and Gtf3a 1 0.00 1.68 0
61 INT356084 Binding of Notch1 and Ncstn 1 0.01 0.07 0
62 INT264729 Mir199b Regulation of Hes1 1 0.05 0.25 0
63 INT303386 Binding of Jag1 and Laptm5 1 0.02 0 0
64 INT285769 Das Regulation of NOTCH1 1 0.00 0.78 0
65 INT303390 Binding of Jag1 and Myo1f 1 0.07 0 0
66 INT197310 Hes1 Regulation of Ascl1 1 0.01 0.14 0
67 INT193947 Notch1 Positive_regulation of Alph1 1 0.01 0.07 0
68 INT303400 Jag1 Positive_regulation of Protein_catabolism of Gopc 1 0.25 0 0
69 INT291333 Binding of CSHL1 and NOTCH1 1 0.05 1.16 0
70 INT299456 Binding of Gabpa and Notch1 1 0.21 0.09 0
71 INT264725 Binding of Hes1 and Notch1 1 0.03 0.84 0
72 INT264734 Mir199b Negative_regulation of Negative_regulation of Hes1 1 0.07 0.1 0
73 INT258564 Binding of NOTCH1 and Crlf2 1 0.27 0.67 0
74 INT264739 Mir199b Negative_regulation of Gene_expression of Hes1 1 0.07 0.82 0
75 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0
76 INT303395 Positive_regulation of Binding of Jag1 and Myo1f 1 0.07 0 0
77 INT264733 Hes1 Regulation of Mir199b 1 0.05 0.43 0
78 INT273887 Binding of Jag1 and Notch2 1 0.02 1.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of stem cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of stem cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
2 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
3 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7
4 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54
5 INT62678 Negative_regulation of JAG1 8 0.41 6.95 3.5
6 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
7 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64
8 INT50057 Regulation of Notch1 3 0.39 0.87 2.14
9 INT303352 Gene_expression of Jag1 19 0.73 7.68 1.89
10 INT140036 Positive_regulation of Gene_expression of Notch1 6 0.61 2 1.86
11 INT52633 Negative_regulation of Notch1 4 0.42 2.99 1.84
12 INT6830 Positive_regulation of Notch1 20 0.55 7.91 1.57
13 INT117033 Gene_expression of JAG1 13 0.65 11.46 1.52
14 INT163381 Transcription of Notch1 2 0.69 0.41 1.52
15 INT130098 Negative_regulation of NOTCH1 11 0.42 5.45 1.33
16 INT110784 Protein_catabolism of Notch1 8 0.21 2.32 1.31
17 INT149295 Regulation of NOTCH1 10 0.13 4.26 1.22
18 INT303362 Regulation of Jag1 2 0.22 2.91 1.22
19 INT110780 Localization of Notch1 2 0.06 0.47 1.19
20 INT149292 Localization of NOTCH1 7 0.54 6.11 1.14
21 INT123727 Negative_regulation of Notch1 6 0.21 1.22 1.11
22 INT6833 Binding of Notch1 4 0.36 0.05 0.94
23 INT303347 Positive_regulation of Gene_expression of Jag1 6 0.65 4.06 0.77
24 INT140037 Positive_regulation of Positive_regulation of Notch1 2 0.22 1.34 0.69
25 INT264709 Gene_expression of Hes1 24 0.76 7.04 0.63
26 INT74781 Regulation of JAG1 6 0.39 2.75 0.63
27 INT148382 Positive_regulation of JAG1 5 0.23 3.88 0.63
28 INT6831 Negative_regulation of Binding of Notch1 1 0.27 0 0.6
29 INT136920 Positive_regulation of Gene_expression of NOTCH1 12 0.49 8.25 0.59
30 INT151401 Localization of JAG1 4 0.65 1.88 0.58
31 INT110782 Negative_regulation of Localization of Notch1 1 0.03 0.33 0.56
32 INT149294 Regulation of Localization of NOTCH1 1 0.10 0.9 0.55
33 INT110785 Positive_regulation of Protein_catabolism of Notch1 1 0.05 0.33 0.55
34 INT149297 Protein_catabolism of NOTCH1 2 0.15 0.87 0.51
35 INT158426 Binding of NOTCH1 10 0.36 7.95 0.45
36 INT151400 Binding of JAG1 14 0.37 7.96 0.39
37 INT258685 Regulation of Gene_expression of Notch1 2 0.40 1.45 0.3
38 INT273867 Binding of Jag1 18 0.45 3.14 0.25
39 INT303374 Negative_regulation of Jag1 2 0.48 0.9 0.23
40 INT316049 Regulation of Regulation of Notch1 1 0.03 0.92 0.23
41 INT130099 Negative_regulation of Positive_regulation of NOTCH1 4 0.43 2.56 0.21
42 INT297241 Positive_regulation of Positive_regulation of Notch1 2 0.40 1.02 0.2
43 INT193945 Binding of Notch1 7 0.15 1.28 0.19
44 INT130096 Positive_regulation of Positive_regulation of NOTCH1 2 0.50 1.15 0.18
45 INT264701 Negative_regulation of Gene_expression of Hes1 1 0.42 0.73 0.18
46 INT297239 Positive_regulation of Gene_expression of Notch1 2 0.40 1.31 0.13
47 INT338718 Positive_regulation of Localization of NOTCH1 1 0.04 0.6 0.13
48 INT316042 Negative_regulation of Gene_expression of Notch1 1 0.27 1.7 0.12
49 INT141999 Regulation of Gene_expression of NOTCH1 2 0.04 0.97 0.08
50 INT327728 Regulation of Gene_expression of Notch1 2 0.27 0.73 0.07
51 INT298251 Gene_expression of Hes5 2 0.45 0.39 0.06
52 INT193845 Localization of Notch1 2 0.78 0.32 0.05
53 INT193850 Regulation of Localization of Notch1 1 0.14 0.33 0.05
54 INT219231 Positive_regulation of Gene_expression of JAG1 1 0.40 1.18 0.05
55 INT298336 Phosphorylation of Notch1 1 0.02 0.13 0.04
56 INT264717 Negative_regulation of Hes1 7 0.42 0.77 0.03
57 INT264704 Regulation of Hes1 4 0.44 1.03 0.03
58 INT350959 Transcription of NOTCH1 2 0.05 0.84 0.03
59 INT264702 Positive_regulation of Gene_expression of Hes1 1 0.68 1.39 0.03
60 INT303349 Positive_regulation of Jag1 5 0.57 1.23 0
61 INT232397 Protein_catabolism of Notch1 3 0.64 1.56 0
62 INT264719 Regulation of Gene_expression of Hes1 2 0.28 0.12 0
63 INT286388 Transcription of Jag1 2 0.65 0.64 0
64 INT264708 Transcription of Hes1 1 0.67 0.83 0
65 INT297242 Transcription of Notch1 1 0.19 0.25 0
66 INT264724 Negative_regulation of Positive_regulation of Notch1 1 0.03 0.77 0
67 INT300174 Negative_regulation of Gene_expression of NOTCH1 1 0.04 0.53 0
68 INT303366 Negative_regulation of Gene_expression of Jag1 1 0.55 0.48 0
69 INT264705 Binding of Hes1 1 0.35 0.07 0
70 INT234247 Negative_regulation of Protein_catabolism of NOTCH1 1 0.05 0 0
71 INT298236 Localization of Hes5 1 0.51 0.39 0
72 INT130094 Regulation of Positive_regulation of NOTCH1 1 0.45 0.52 0
73 INT264706 Positive_regulation of Hes1 1 0.40 0.14 0
74 INT303370 Protein_catabolism of Jag1 1 0.62 0.05 0
75 INT257560 Regulation of Negative_regulation of JAG1 1 0.13 0.48 0
76 INT303356 Localization of Jag1 1 0.70 0.09 0
77 INT303348 Positive_regulation of Transcription of Jag1 1 0.44 0.64 0
78 INT303353 Negative_regulation of Binding of Jag1 1 0.40 0 0
79 INT264723 Negative_regulation of Gene_expression of Notch1 1 0.03 0.83 0
80 INT327858 Positive_regulation of Protein_catabolism of Notch1 1 0.45 0.13 0
81 INT303367 Negative_regulation of Positive_regulation of Jag1 1 0.35 0.28 0
82 INT327861 Positive_regulation of Localization of Notch1 1 0.67 0 0
83 INT273836 Positive_regulation of Regulation of Notch1 1 0.15 0.05 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox