GO:2001241

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Name positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
Categary Process
Go Slim No
Go Link GO:2001241
Unique Molecular Interactions 37
Total Molecular Interactions 39
Total Single Events 399
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of extrinsic apoptotic signaling pathway in absence of ligand. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of extrinsic apoptotic signaling pathway in absence of ligand. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT180814 Binding of Ret and Gdnf 1 0.01 1.31 1.17
2 INT147507 Binding of Ret and Gtf3a 1 0.03 0.81 0.92
3 INT147505 Binding of Ret and Gdnf 1 0.27 0.81 0.92
4 INT338390 Thim Regulation of Gene_expression of Ret 1 0.02 0.43 0.65
5 INT114845 RET Regulation of Gene_expression of Lgals1 1 0.02 0.84 0.65
6 INT280895 Runx1 Positive_regulation of Gene_expression of Ret 2 0.33 0.2 0.58
7 INT98034 Binding of Ret and Trpv1 1 0.43 0.42 0.58
8 INT242613 Binding of Gfra2 and Ret 1 0.02 0 0.52
9 INT242628 Binding of Gfra1 and Ret 1 0.03 0 0.46
10 INT242615 Ret Positive_regulation of Gene_expression of Gfra1 1 0.04 0 0.46
11 INT242596 Binding of Ntrk1 and Ret 1 0.12 0 0.46
12 INT242607 Negative_regulation of Ntrk1 Positive_regulation of Ret 1 0.16 0 0.39
13 INT223470 Ret Regulation of Ntrk1 1 0.21 0 0.36
14 INT148240 Binding of Kit and Ret 1 0.24 0.44 0.35
15 INT245563 Negative_regulation of Runx1 Regulation of Ret 1 0.39 0.76 0.29
16 INT245556 Runx1 Regulation of Ret 1 0.56 0.76 0.29
17 INT242632 Ret Positive_regulation of Gene_expression of Trpa1 1 0.33 0.09 0.18
18 INT96518 Regulation of Gdnf Positive_regulation of Ret 1 0.00 0.23 0.11
19 INT258527 Binding of BRAF and RET 1 0.21 1.49 0.11
20 INT96519 Gdnf Positive_regulation of Ret 1 0.00 0.22 0.1
21 INT242627 Ngf Positive_regulation of Gene_expression of Ret 1 0.32 0.1 0.1
22 INT258522 Binding of DDR1 and RET 1 0.03 1.05 0.1
23 INT242594 Binding of Gdnf and Ret 1 0.21 0 0.08
24 INT242636 Ret Positive_regulation of Gene_expression of Slc18a3 1 0.20 0 0.06
25 INT137870 Binding of Artn and Ret 1 0.25 0.16 0.05
26 INT199159 Binding of RET and Pheo 1 0.04 1.42 0.03
27 INT211883 Binding of RET and CDCP1 1 0.00 2.12 0
28 INT223471 Dok4 Regulation of Ret 1 0.30 0.17 0
29 INT240271 Binding of GDNF and RET 1 0.09 1.04 0
30 INT242620 Tg(CAG-EGFP)D4Nagy Negative_regulation of Ret 1 0.02 0 0
31 INT242619 Ret Negative_regulation of Transcription of Slc18a3 1 0.18 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of extrinsic apoptotic signaling pathway in absence of ligand. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of extrinsic apoptotic signaling pathway in absence of ligand. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT79979 Gene_expression of Ret 94 0.75 19.21 25.51
2 INT64849 Gene_expression of Ret 24 0.75 14.36 9.1
3 INT242569 Positive_regulation of Ret 17 0.55 3.61 3.54
4 INT38631 Positive_regulation of Ret 8 0.39 3.23 2.52
5 INT63333 Gene_expression of RET 24 0.76 30.09 2.41
6 INT242548 Regulation of Gene_expression of Ret 7 0.49 1.2 2.33
7 INT50392 Regulation of Ret 6 0.54 3.51 2.22
8 INT242551 Negative_regulation of Gene_expression of Ret 5 0.41 1.01 2.21
9 INT102896 Binding of Ret 8 0.35 1.55 2.03
10 INT242572 Positive_regulation of Gene_expression of Ret 6 0.40 0.29 1.56
11 INT44746 Localization of Ret 3 0.48 1.23 1.28
12 INT223448 Localization of Ret 2 0.60 0.58 1.23
13 INT109396 Negative_regulation of RET 12 0.42 14.92 1.06
14 INT208932 Regulation of Ret 6 0.49 1.49 0.97
15 INT2425 Negative_regulation of Ret 3 0.58 1.77 0.94
16 INT92002 Transcription of Ret 3 0.43 1.58 0.9
17 INT83461 Binding of RET 8 0.47 9.7 0.87
18 INT79784 Positive_regulation of RET 15 0.57 17.43 0.71
19 INT114842 Localization of RET 3 0.71 5.98 0.71
20 INT66940 Regulation of RET 7 0.52 5.61 0.69
21 INT91993 Regulation of Gene_expression of Ret 3 0.42 2.42 0.55
22 INT245546 Negative_regulation of Positive_regulation of Ret 2 0.34 0.89 0.49
23 INT140868 Positive_regulation of Gene_expression of Ret 1 0.50 0.32 0.42
24 INT242520 Negative_regulation of Ret 1 0.35 2.49 0.26
25 INT153553 Positive_regulation of Gene_expression of RET 1 0.67 1.38 0.12
26 INT242576 Positive_regulation of Regulation of Ret 1 0.35 0.09 0.08
27 INT153554 Positive_regulation of Binding of RET 1 0.45 0.83 0.07
28 INT199153 Phosphorylation of RET 1 0.44 1.73 0.04
29 INT292130 Negative_regulation of Gene_expression of RET 1 0.12 1.37 0.04
30 INT242574 Positive_regulation of Positive_regulation of Ret 1 0.40 0.12 0.04
31 INT356267 Binding of Ret 1 0.08 0 0.03
32 INT338104 Transcription of RET 1 0.54 0.59 0
33 INT242580 Regulation of Positive_regulation of Ret 1 0.36 0.69 0
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