GO:2001244

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Name positive regulation of intrinsic apoptotic signaling pathway
Categary Process
Go Slim No
Go Link GO:2001244
Unique Molecular Interactions 238
Total Molecular Interactions 325
Total Single Events 2456
Pain Genes Associated 18

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of intrinsic apoptotic signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of intrinsic apoptotic signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49
2 INT251164 Binding of Clu and Trpv1 1 0.19 0.44 2.23
3 INT73597 Positive_regulation of BAX Positive_regulation of Casp1 1 0.06 0.69 1.28
4 INT73598 BAX Positive_regulation of Casp1 1 0.06 0.63 1.27
5 INT166388 Binding of Gnb2l1 and Mapk1 1 0.49 0.49 1.21
6 INT153685 Binding of Bcl2l11 and Gtpbp4 1 0.08 0.76 0.93
7 INT251159 Binding of Clu and Positive_regulation of Trpv1 1 0.16 0 0.87
8 INT158684 MAPK8 Positive_regulation of Gene_expression of BCL2L11 1 0.51 0.44 0.78
9 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77
10 INT101675 Bcl2l11 Regulation of Localization of Ggh 1 0.03 0 0.72
11 INT166386 Mapk1 Regulation of Gene_expression of Gnb2l1 1 0.46 0.25 0.7
12 INT251169 Clu Regulation of Ca2 1 0.03 0.66 0.7
13 INT251166 Clu Positive_regulation of Trpc3 1 0.09 0.75 0.67
14 INT251171 Clu Positive_regulation of C6 1 0.05 0.75 0.67
15 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
16 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
17 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
18 INT251188 Clu Positive_regulation of TRPV1 1 0.01 0.23 0.64
19 INT166387 Binding of Gnb2l1 and Mdk 1 0.30 0.24 0.61
20 INT112699 Bid Regulation of Bax 1 0.25 0.51 0.61
21 INT166385 Binding of Araf and Gnb2l1 1 0.23 0.24 0.6
22 INT251167 Clu Positive_regulation of Trpc6 1 0.12 0.2 0.6
23 INT251168 Clu Positive_regulation of Trpc7 1 0.15 0.2 0.59
24 INT330544 Bcl2l11 Negative_regulation of Prkcg 1 0.03 0.38 0.52
25 INT330553 Bcl2l11 Negative_regulation of Camk2a 1 0.01 0.38 0.52
26 INT330541 Bcl2l11 Negative_regulation of Negative_regulation of Prkcg 1 0.03 0.38 0.52
27 INT330545 Bcl2l11 Negative_regulation of Trib3 1 0.00 0.38 0.52
28 INT228449 PMAIP1 Negative_regulation of Fgf2 1 0.00 0.07 0.49
29 INT228448 PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49
30 INT228447 Negative_regulation of PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49
31 INT352892 Binding of CAV1 and ITGA2 1 0.20 1.61 0.47
32 INT145260 Binding of CLU and App 1 0.00 0.74 0.46
33 INT69637 Binding of CAV1 and Zfp354a 1 0.00 0 0.46
34 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
35 INT244050 Binding of Gnb2l1 and Prkca 1 0.01 0 0.45
36 INT116613 Lnpep Negative_regulation of Gene_expression of BAX 1 0.42 0.62 0.43
37 INT116612 Lnpep Negative_regulation of BAX 1 0.42 0.62 0.42
38 INT51341 Binding of Pomc and Clu 1 0.14 0 0.38
39 INT60817 Binding of Sstr1 and Bcl2l11 1 0.06 0 0.37
40 INT172213 Binding of BAX and BCL2L1 3 0.22 4.02 0.35
41 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34
42 INT228446 PMAIP1 Regulation of Transcription of Mtpn 1 0.00 0 0.34
43 INT134080 OPA1 Negative_regulation of Phosphorylation of Gnb2l1 1 0.03 0.22 0.34
44 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
45 INT163762 MDM2 Positive_regulation of Gene_expression of BAX 1 0.27 0.86 0.3
46 INT224131 Binding of CAV1 and Agtr1a 1 0.00 0.08 0.3
47 INT141870 Binding of Slc2a4 and Cav1 1 0.36 0.38 0.28
48 INT170719 Binding of Grm5 and Siah1a 1 0.01 1.1 0.28
49 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
50 INT237919 BAX Positive_regulation of Protein_catabolism of PARP1 1 0.03 1.41 0.26
51 INT130056 PPARG Positive_regulation of CAV1 1 0.02 0.53 0.25
52 INT288582 Binding of Cav1 and Kcnma1 1 0.11 0 0.22
53 INT220528 Ugt1a6b Positive_regulation of Cav1 1 0.01 1.31 0.22
54 INT330051 Mapk8 Positive_regulation of Bcl2l11 1 0.13 0.46 0.21
55 INT170721 Siah1a Regulation of Negative_regulation of Grm2 1 0.22 0 0.18
56 INT155063 Csf2 Negative_regulation of Gene_expression of Bax 1 0.27 1.46 0.18
57 INT251162 Clu Positive_regulation of Gene_expression of Trpv1 1 0.20 0.07 0.18
58 INT155066 Csf2 Negative_regulation of Bax 1 0.12 1.89 0.17
59 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
60 INT220520 Ugt1a6b Positive_regulation of Gene_expression of Cav1 1 0.01 0.81 0.17
61 INT155232 TXNIP Regulation of BAX 1 0.23 0.15 0.17
62 INT336891 Epo Negative_regulation of Transcription of Bax 1 0.10 0.68 0.16
63 INT170724 Binding of Grm8 and Siah1a 1 0.19 0.11 0.15
64 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
65 INT155644 Binding of CAV1 and HSD11B1 1 0.39 0.77 0.15
66 INT333241 Cxcl12 Regulation of Bcl2l11 1 0.18 1.11 0.15
67 INT130918 HMHA1 Positive_regulation of BAX 1 0.04 1.37 0.14
68 INT315030 Binding of Cav1 and Tmie 1 0.03 0.25 0.14
69 INT315032 Binding of Cav1 and Ryr1 1 0.27 0.2 0.14
70 INT273040 Vip Regulation of Bax 1 0.23 1.69 0.13
71 INT353897 Negative_regulation of Prkcg Negative_regulation of Localization of Bcl2l11 1 0.08 0.4 0.13
72 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13
73 INT226192 Protein_catabolism of Bax Positive_regulation of Gtf3a 1 0.00 0.53 0.12
74 INT182481 Binding of Cav1 and Ighg2b 1 0.10 0 0.12
75 INT182482 Binding of Cav1 and Cxcl16 1 0.07 0 0.12
76 INT311871 Cav1 Regulation of Mch 1 0.01 0.24 0.11
77 INT285030 Binding of Bax and Slc25a4 1 0.03 0.84 0.11
78 INT265890 BCL2 Regulation of Gene_expression of BAX 1 0.04 1.08 0.1
79 INT265889 BAX Regulation of Gene_expression of BAD 1 0.06 1.08 0.1
80 INT220517 Negative_regulation of Ugt1a6b Positive_regulation of Cav1 1 0.01 0.35 0.1
81 INT333242 Bcl2l11 Positive_regulation of Gene_expression of Cxcl12 1 0.18 1.48 0.1
82 INT51344 Binding of Clu and Vtn 1 0.06 0 0.1
83 INT310743 TP53 Regulation of BAX 1 0.09 1.11 0.1
84 INT239643 Binding of BCL2 and BCL2L11 3 0.16 2.26 0.09
85 INT302979 Binding of Gnb2l1 and Smpd2 1 0.07 0.71 0.09
86 INT302977 Binding of Cav1 and Smpd2 1 0.08 0.71 0.09
87 INT220511 Cav1 Negative_regulation of Transcription of Ccnd1 1 0.03 0.83 0.09
88 INT137252 BCL2L11 Regulation of NCAM1 1 0.20 0.99 0.08
89 INT333251 Binding of Bcl2l11 and Cxcl12 1 0.14 1.74 0.08
90 INT137254 BCL2L11 Regulation of VIM 1 0.17 0.99 0.08
91 INT137251 BCL2L11 Regulation of CDH1 1 0.17 0.99 0.08
92 INT309159 Binding of Cav1 and Positive_regulation of Localization of Esr1 1 0.04 0 0.08
93 INT137255 BCL2L11 Regulation of SLC4A3 1 0.10 0.99 0.08
94 INT137256 BCL2L11 Regulation of SLC4A1 1 0.24 0.99 0.08
95 INT137253 BCL2L11 Regulation of CD99 1 0.23 0.99 0.08
96 INT285032 Bnip3 Positive_regulation of Bax 1 0.28 0.77 0.07
97 INT340401 Positive_regulation of Bax Positive_regulation of Binding of Hrk 1 0.01 0.79 0.07
98 INT170722 Siah1a Regulation of Gene_expression of Grm8 1 0.24 0 0.07
99 INT340395 Binding of Bax and Tg(CAG-EGFP)D4Nagy 1 0.02 0.43 0.07
100 INT302175 BAX Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06
101 INT302129 BAX Regulation of Positive_regulation of CASP3 1 0.02 0.69 0.06
102 INT183853 Gene_expression of CAV1 Negative_regulation of Positive_regulation of MAPK1 1 0.28 0.25 0.05
103 INT306510 INCENP Regulation of Gene_expression of Clu 1 0.00 1.92 0.05
104 INT234379 BAX Positive_regulation of CASP3 1 0.04 1.16 0.04
105 INT172214 BAX Positive_regulation of TP53 1 0.09 0.37 0.04
106 INT333245 Binding of Bcl2 and Bcl2l11 1 0.03 0.87 0.04
107 INT306505 Binding of Clu and Tnf 1 0.24 0.4 0.04
108 INT340394 Binding of Bax and Bbc3 1 0.01 0.36 0.04
109 INT306501 Negative_regulation of Binding of Clu and Tnf 1 0.29 0.4 0.04
110 INT172902 Binding of Bax and Bcl2 5 0.30 3.19 0.03
111 INT190738 Adcyap1 Positive_regulation of Gene_expression of Gnb2l1 1 0.08 0 0.03
112 INT297737 Cbr1 Positive_regulation of Bax 1 0.06 0.53 0.03
113 INT220512 Cav1 Regulation of Positive_regulation of Cdkn1b 1 0.06 0.85 0.03
114 INT238395 BAX Regulation of CDKN1A 1 0.03 0.31 0.03
115 INT333259 Bcl2 Regulation of Bax 1 0.03 0.32 0.03
116 INT224676 Binding of Bax and Mcl1 1 0.01 1.09 0.03
117 INT183896 Gene_expression of CAV1 Negative_regulation of Positive_regulation of Racgap1 1 0.01 0.64 0.03
118 INT224690 Mcl1 Regulation of Bax 1 0.00 1.09 0.03
119 INT341376 Sod2 Regulation of Bax 1 0.09 0.99 0.03
120 INT185852 Binding of BAK1 and BAX 3 0.29 2.5 0
121 INT178861 Binding of BAX and BCL2 3 0.27 3.07 0
122 INT172906 Binding of Bax and Bcl2l1 2 0.16 2.03 0
123 INT198011 Binding of BAX and MCL1 2 0.20 3.04 0
124 INT351167 CAV1 Negative_regulation of Ppp2r1a 1 0.08 1.5 0
125 INT306500 Clu Regulation of Esr1 1 0.22 0.13 0
126 INT342737 Pink1 Positive_regulation of HTRA2 1 0.29 0.58 0
127 INT288584 Cav1 Regulation of Gene_expression of Kcnma1 1 0.14 0 0
128 INT198014 Binding of MCL1 and BCL2L11 1 0.11 0.82 0
129 INT288594 Regulation of Binding of CAV1 and Kcnma1 1 0.01 0 0
130 INT288588 Binding of Cav1 and Neu3 1 0.01 0 0
131 INT285029 Binding of Bax and Bcl2l1 1 0.25 0.1 0
132 INT330047 Binding of Bax and Bcl2l11 1 0.13 0.62 0
133 INT183895 CAV1 Regulation of Positive_regulation of Racgap1 1 0.01 0.37 0
134 INT191058 Binding of Bcl2 and Positive_regulation of Gene_expression of Bax 1 0.21 0.49 0
135 INT249169 PMAIP1 Positive_regulation of PRKDC 1 0.00 0 0
136 INT345505 E2f1 Positive_regulation of PMAIP1 1 0.18 0.62 0
137 INT327971 PNLIP Positive_regulation of Gene_expression of BAX 1 0.43 1.95 0
138 INT292500 Mlph Regulation of Gene_expression of BAX 1 0.00 0.4 0
139 INT106380 ARSA Regulation of Gene_expression of BAX 1 0.06 0.12 0
140 INT284919 XRCC6 Negative_regulation of BAX 1 0.01 0.64 0
141 INT345489 TP53 Positive_regulation of PMAIP1 1 0.05 0.6 0
142 INT321400 VEGFA Negative_regulation of Gene_expression of BAX 1 0.03 0.75 0
143 INT330055 Binding of Bcl2l11 and Hrk 1 0.02 0.62 0
144 INT242483 Negative_regulation of Ciapin1 Negative_regulation of Positive_regulation of Bax 1 0.17 1.76 0
145 INT351166 Gtf3a Positive_regulation of Gene_expression of CAV1 1 0.01 0.79 0
146 INT136914 Mapk8 Positive_regulation of Localization of Bax 1 0.51 0.12 0
147 INT351156 VEGFA Positive_regulation of Gene_expression of CAV1 1 0.07 0.79 0
148 INT170723 Binding of Calm2 and Siah1a 1 0.24 0 0
149 INT280961 Binding of Cav1 and Cpox 1 0.04 0 0
150 INT306509 Binding of XRCC6 and Clu 1 0.37 0.27 0
151 INT170718 Siah1a Regulation of Grm8 1 0.24 0 0
152 INT322664 Prdm8 Positive_regulation of Gene_expression of Bax 1 0.01 1.1 0
153 INT327972 Negative_regulation of BCL2 Positive_regulation of BAX 1 0.22 0.82 0
154 INT345484 Binding of MCL1 and PMAIP1 1 0.04 0.8 0
155 INT288587 Cav1 Regulation of Binding of Kcnma1 1 0.14 0 0
156 INT285028 Binding of Bcl2 and Bax 1 0.32 0.1 0
157 INT288597 Binding of CAV1 and Kcnma1 1 0.01 0.17 0
158 INT236528 Binding of Cav1 and Flna 1 0.06 0.09 0
159 INT342736 Pink1 Positive_regulation of Phosphorylation of HTRA2 1 0.29 0.58 0
160 INT288596 Positive_regulation of Binding of CAV1 and Kcnma1 1 0.01 0.1 0
161 INT288590 Binding of Cav1 and Abhd14a 1 0.00 0 0
162 INT183857 CAV1 Positive_regulation of RHOC 1 0.46 0.21 0
163 INT333248 Bcl2l11 Regulation of Gene_expression of Cxcl12 1 0.11 0.52 0
164 INT183861 Binding of CAV1 and CDC42EP5 1 0.03 3.21 0
165 INT288593 Cav1 Positive_regulation of Binding of Kcnma1 1 0.15 0 0
166 INT229821 Fos Positive_regulation of Bax 1 0.15 0.27 0
167 INT183864 Gene_expression of CAV1 Negative_regulation of Positive_regulation of RHOC 1 0.39 0.95 0
168 INT351165 Binding of CAV1 and Nos3 1 0.09 1.46 0
169 INT309517 Binding of Bax and Xrcc6 1 0.15 0.5 0
170 INT201761 BIK Positive_regulation of Positive_regulation of Bax 1 0.01 0.43 0
171 INT113343 Phosphorylation of TP53 Positive_regulation of Gene_expression of BAX 1 0.11 0.14 0
172 INT292456 AKT1 Regulation of BAX 1 0.00 0.76 0
173 INT330052 Binding of Bax and Bid 1 0.15 0.62 0
174 INT351157 TSC1 Positive_regulation of Gene_expression of CAV1 1 0.01 1.43 0
175 INT322662 Binding of Bax and Pbrm1 1 0.08 0.9 0
176 INT172908 Binding of Bad and Bax 1 0.01 1.34 0
177 INT330057 Bid Positive_regulation of Bax 1 0.19 0.62 0
178 INT297208 Myoz1 Regulation of Dnm1l 1 0.05 0.17 0
179 INT183860 Binding of RHOC and CAV1 1 0.34 0.4 0
180 INT185855 Binding of BAX and BIK 1 0.29 0.65 0
181 INT313426 Positive_regulation of Ppp2ca Positive_regulation of Bax 1 0.46 0.36 0
182 INT183856 Negative_regulation of RHOC Positive_regulation of Gene_expression of CAV1 1 0.42 0.09 0
183 INT267252 Bax Regulation of Bak1 1 0.05 1.09 0
184 INT201765 Binding of BCL2L1 and Bax 1 0.00 0.28 0
185 INT183868 CAV1 Positive_regulation of PAF1 1 0.54 0.41 0
186 INT288591 Cav1 Positive_regulation of Kcnma1 1 0.15 0 0
187 INT237918 BID Positive_regulation of Gene_expression of BAX 1 0.04 1.31 0
188 INT262498 Binding of Aqp1 and Cav1 1 0.03 0.56 0
189 INT201763 BID Positive_regulation of Positive_regulation of Bax 1 0.01 0.43 0
190 INT242476 Negative_regulation of Ciapin1 Positive_regulation of Bax 1 0.19 1.29 0
191 INT185850 BID Positive_regulation of BAX 1 0.41 0.73 0
192 INT345486 PMAIP1 Positive_regulation of Localization of CYC1 1 0.18 0.96 0
193 INT322670 Prdm8 Positive_regulation of Bax 1 0.01 1.1 0
194 INT298103 Binding of Cav1 and Ca2 1 0.03 0 0
195 INT275753 xn Regulation of Bax 1 0.05 1.31 0
196 INT333681 Trp53 Regulation of Negative_regulation of Bax 1 0.15 1.17 0
197 INT334718 Binding of NOS1 and Bax 1 0.02 0.87 0
198 INT238398 ELANE Positive_regulation of Gene_expression of BAX 1 0.05 0.47 0
199 INT351164 CAV1 Negative_regulation of Ppp1cc 1 0.11 1.5 0
200 INT292451 PTK2 Regulation of BAX 1 0.02 0.76 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of intrinsic apoptotic signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of intrinsic apoptotic signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
2 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94
3 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
4 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75
5 INT58986 Gene_expression of Clu 17 0.77 8.35 9.61
6 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
7 INT159116 Gene_expression of Gnb2l1 12 0.77 2.79 9.49
8 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
9 INT73596 Positive_regulation of Gene_expression of BAX 43 0.67 40.97 9.22
10 INT73595 Positive_regulation of BAX 61 0.61 56.97 7.82
11 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
12 INT166383 Positive_regulation of Gene_expression of Gnb2l1 1 0.69 2.19 7.02
13 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
14 INT159115 Negative_regulation of Gene_expression of Gnb2l1 3 0.42 1.33 5.59
15 INT51337 Binding of Clu 3 0.12 0.05 5.45
16 INT145929 Regulation of Bax 20 0.60 18.12 5.35
17 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06
18 INT159122 Positive_regulation of Gnb2l1 8 0.69 2.2 4.61
19 INT99504 Negative_regulation of Bax 19 0.56 8.89 4.44
20 INT101858 Negative_regulation of BAX 25 0.57 23.77 4.16
21 INT84686 Regulation of BAX 26 0.49 28.54 4.13
22 INT141443 Phosphorylation of Cav1 6 0.82 4.39 4.03
23 INT123752 Regulation of Bax 19 0.60 16.45 4
24 INT112692 Localization of Bax 31 0.80 20.97 3.98
25 INT153666 Gene_expression of CAV1 156 0.77 120.99 3.9
26 INT124579 Localization of BAX 35 0.78 30.31 3.43
27 INT35946 Positive_regulation of Clu 12 0.69 4.92 2.73
28 INT86703 Positive_regulation of Gene_expression of Cav1 7 0.70 3.58 2.73
29 INT166381 Negative_regulation of Gnb2l1 1 0.43 0.73 2.68
30 INT159117 Regulation of Gene_expression of Gnb2l1 3 0.56 0.5 2.36
31 INT102146 Phosphorylation of Bax 4 0.66 3.48 2.35
32 INT170712 Gene_expression of Siah1a 1 0.77 2.33 2.33
33 INT136614 Positive_regulation of Cav1 5 0.46 2.28 2.23
34 INT103966 Negative_regulation of Gene_expression of BAX 9 0.56 7.95 2.14
35 INT77627 Regulation of Gene_expression of BAX 14 0.44 15.09 2.12
36 INT154970 Localization of Bax 15 0.74 11.12 2.11
37 INT69702 Positive_regulation of PMAIP1 7 0.35 8.81 1.98
38 INT112089 Gene_expression of Cav1 73 0.75 23.8 1.97
39 INT98836 Transcription of Bax 6 0.69 5.04 1.96
40 INT228129 Negative_regulation of Bcl2l11 10 0.58 11.08 1.93
41 INT107905 Gene_expression of BCL2L11 9 0.75 7.58 1.92
42 INT134442 Transcription of Bax 14 0.67 7.6 1.9
43 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89
44 INT153684 Negative_regulation of Bcl2l11 3 0.31 1.19 1.89
45 INT134443 Binding of Bax 10 0.47 5.62 1.84
46 INT49347 Negative_regulation of Clu 4 0.58 1.63 1.79
47 INT159120 Protein_catabolism of Gnb2l1 1 0.26 0.37 1.79
48 INT104883 Positive_regulation of Positive_regulation of Bax 4 0.45 4.05 1.74
49 INT141444 Positive_regulation of Phosphorylation of Cav1 1 0.70 1.76 1.69
50 INT60815 Binding of Bcl2l11 2 0.27 0.95 1.67
51 INT135955 Positive_regulation of Cav1 17 0.48 7.73 1.61
52 INT146785 Positive_regulation of Localization of Bax 7 0.69 6.16 1.47
53 INT109512 Negative_regulation of Gene_expression of Bax 12 0.42 8.04 1.44
54 INT35944 Regulation of Clu 4 0.20 0.15 1.3
55 INT112695 Negative_regulation of Protein_catabolism of Bax 3 0.36 1.72 1.3
56 INT154969 Positive_regulation of Localization of Bax 4 0.64 3.42 1.27
57 INT228128 Gene_expression of Bcl2l11 31 0.67 18.31 1.25
58 INT141862 Binding of Cav1 11 0.36 1.32 1.25
59 INT107904 Positive_regulation of Gene_expression of BCL2L11 3 0.53 2.22 1.24
60 INT251180 Phosphorylation of Clu 1 0.29 0.79 1.22
61 INT122988 Gene_expression of CLU 28 0.75 24.07 1.21
62 INT303667 Regulation of BCL2L11 3 0.16 1.03 1.21
63 INT112693 Protein_catabolism of Bax 5 0.74 3.17 1.2
64 INT139764 Negative_regulation of CAV1 10 0.58 6.57 1.14
65 INT141189 Negative_regulation of Transcription of Bax 1 0.41 1.42 1.14
66 INT233561 Gene_expression of Clu 14 0.66 45.63 1.07
67 INT136613 Negative_regulation of Cav1 2 0.57 2.28 0.96
68 INT175507 Regulation of Gene_expression of Bax 13 0.50 10.91 0.95
69 INT98134 Binding of BAX 17 0.39 11.45 0.93
70 INT153670 Positive_regulation of Gene_expression of CAV1 26 0.69 44.27 0.92
71 INT228130 Positive_regulation of Bcl2l11 14 0.49 10 0.9
72 INT100273 Localization of Clu 4 0.61 0.49 0.88
73 INT141442 Negative_regulation of Phosphorylation of Cav1 1 0.59 0.94 0.87
74 INT137512 Positive_regulation of Positive_regulation of BAX 5 0.49 4.91 0.85
75 INT144697 Regulation of Gene_expression of Bax 8 0.37 9.5 0.81
76 INT82896 Transcription of BAX 3 0.67 4.61 0.8
77 INT112090 Negative_regulation of Gene_expression of Cav1 8 0.57 3.5 0.78
78 INT130057 Positive_regulation of CAV1 12 0.65 8.96 0.77
79 INT148984 Positive_regulation of Localization of BAX 6 0.48 5.29 0.77
80 INT70666 Positive_regulation of CLU 16 0.45 12.95 0.74
81 INT112088 Regulation of Cav1 2 0.44 0.51 0.73
82 INT25663 Localization of PMAIP1 3 0.38 2.47 0.71
83 INT94233 Positive_regulation of Gene_expression of Clu 3 0.69 2.64 0.71
84 INT153667 Localization of CAV1 15 0.76 11.92 0.68
85 INT25664 Negative_regulation of Localization of PMAIP1 1 0.09 0.09 0.66
86 INT94232 Negative_regulation of Gene_expression of Clu 2 0.43 1.17 0.63
87 INT86700 Regulation of Cav1 7 0.54 0.92 0.61
88 INT164585 Regulation of PMAIP1 2 0.20 2.07 0.61
89 INT131001 Regulation of CAV1 6 0.44 3.77 0.59
90 INT135294 Negative_regulation of Positive_regulation of Clu 1 0.37 0.35 0.59
91 INT170695 Binding of Siah1a 1 0.48 1.19 0.59
92 INT141863 Negative_regulation of Gene_expression of Cav1 4 0.49 1.77 0.58
93 INT310908 Positive_regulation of Bcl2l11 2 0.38 2.38 0.53
94 INT176242 Binding of Bax 10 0.42 10.18 0.52
95 INT192946 Gene_expression of PMAIP1 2 0.27 1.77 0.52
96 INT164584 Positive_regulation of Positive_regulation of PMAIP1 1 0.20 0.9 0.52
97 INT251182 Regulation of Phosphorylation of Clu 1 0.16 0.13 0.52
98 INT303674 Positive_regulation of Regulation of BCL2L11 1 0.02 0.28 0.5
99 INT102108 Protein_catabolism of Bax 8 0.64 5.69 0.48
100 INT134446 Positive_regulation of Binding of Bax 1 0.49 0.72 0.48
101 INT86702 Localization of Cav1 8 0.69 0.76 0.47
102 INT229243 Negative_regulation of Phosphorylation of BAX 1 0.18 2.32 0.47
103 INT153672 Negative_regulation of Negative_regulation of CAV1 1 0.25 0.2 0.46
104 INT218903 Gene_expression of Bcl2l11 10 0.42 5.19 0.45
105 INT233552 Positive_regulation of Gene_expression of Clu 3 0.59 9.31 0.45
106 INT166382 Positive_regulation of Positive_regulation of Gnb2l1 1 0.50 0.2 0.44
107 INT220504 Positive_regulation of Gene_expression of Cav1 11 0.39 6.26 0.43
108 INT166240 Regulation of Gene_expression of Cav1 3 0.51 1.03 0.43
109 INT152059 Regulation of Transcription of Bax 1 0.26 0.07 0.42
110 INT105888 Phosphorylation of BAX 9 0.80 4.78 0.4
111 INT135802 Positive_regulation of Negative_regulation of Bax 2 0.41 0.57 0.4
112 INT220506 Binding of Cav1 13 0.45 5.46 0.38
113 INT229233 Positive_regulation of Phosphorylation of BAX 1 0.21 1.94 0.38
114 INT228126 Positive_regulation of Gene_expression of Bcl2l11 9 0.50 6.49 0.37
115 INT135953 Negative_regulation of Positive_regulation of Cav1 2 0.37 1.09 0.37
116 INT330551 Regulation of Negative_regulation of Bcl2l11 1 0.06 0 0.36
117 INT163277 Negative_regulation of Gene_expression of CAV1 17 0.56 10.77 0.35
118 INT204069 Negative_regulation of Positive_regulation of Bax 5 0.31 3.08 0.34
119 INT169538 Negative_regulation of Localization of Bax 3 0.49 1.41 0.34
120 INT134072 Negative_regulation of Phosphorylation of Gnb2l1 1 0.11 0.22 0.34
121 INT184482 Positive_regulation of Positive_regulation of Bax 5 0.41 4.7 0.33
122 INT221191 Negative_regulation of Localization of Bax 4 0.38 2.85 0.33
123 INT330552 Negative_regulation of Gene_expression of Bcl2l11 1 0.05 0.12 0.31
124 INT109530 Negative_regulation of Positive_regulation of BAX 3 0.42 3.01 0.3
125 INT134076 Phosphorylation of Gnb2l1 1 0.22 0.22 0.3
126 INT82900 Positive_regulation of Transcription of BAX 2 0.49 1.86 0.29
127 INT141867 Positive_regulation of Transcription of Cav1 2 0.52 0.46 0.29
128 INT141868 Transcription of Cav1 2 0.54 1.48 0.29
129 INT141861 Negative_regulation of Binding of Cav1 1 0.44 0.4 0.29
130 INT140382 Regulation of Gene_expression of BCL2L11 1 0.26 1.18 0.28
131 INT122985 Negative_regulation of Gene_expression of CLU 4 0.57 4.58 0.27
132 INT102111 Positive_regulation of Protein_catabolism of Bax 2 0.45 1.14 0.27
133 INT145259 Binding of CLU 1 0.03 0.84 0.27
134 INT170714 Regulation of Gene_expression of Siah1a 1 0.61 0.71 0.25
135 INT172227 Regulation of Localization of BAX 3 0.26 4.79 0.24
136 INT330033 Phosphorylation of Bcl2l11 1 0.30 0.45 0.24
137 INT135543 Negative_regulation of Positive_regulation of Bax 5 0.30 6.4 0.23
138 INT135956 Phosphorylation of Cav1 5 0.64 2.24 0.22
139 INT135954 Positive_regulation of Phosphorylation of Cav1 2 0.40 0.64 0.22
140 INT141860 Regulation of Localization of Cav1 1 0.20 0.2 0.22
141 INT122987 Negative_regulation of CLU 5 0.42 4.58 0.21
142 INT306279 Transcription of BCL2L11 2 0.67 1.27 0.21
143 INT187553 Regulation of Transcription of BAX 1 0.37 1.21 0.21
144 INT228122 Localization of Bcl2l11 2 0.74 1.08 0.2
145 INT35945 Positive_regulation of Regulation of Clu 1 0.35 0 0.2
146 INT330039 Negative_regulation of Positive_regulation of Bcl2l11 1 0.23 1.02 0.19
147 INT330042 Positive_regulation of Positive_regulation of Bcl2l11 1 0.27 1.02 0.19
148 INT228121 Regulation of Bcl2l11 1 0.45 4.01 0.19
149 INT220497 Regulation of Gene_expression of Cav1 4 0.36 1.84 0.18
150 INT86697 Negative_regulation of Regulation of Cav1 1 0.41 0 0.18
151 INT300463 Regulation of Regulation of Bax 1 0.29 1.33 0.18
152 INT131000 Positive_regulation of Positive_regulation of CAV1 1 0.49 0 0.17
153 INT122984 Localization of CLU 2 0.78 2.46 0.16
154 INT122989 Positive_regulation of Localization of CLU 2 0.45 1.81 0.16
155 INT145253 Negative_regulation of Cav1 9 0.46 3.02 0.15
156 INT163278 Regulation of Gene_expression of CAV1 5 0.45 4.36 0.14
157 INT122986 Positive_regulation of Gene_expression of CLU 3 0.67 2.37 0.14
158 INT228125 Negative_regulation of Gene_expression of Bcl2l11 2 0.37 1.92 0.14
159 INT214975 Localization of Cav1 7 0.75 2.7 0.13
160 INT170700 Positive_regulation of Gene_expression of Siah1a 1 0.50 0.36 0.13
161 INT353892 Localization of Bcl2l11 1 0.22 0.4 0.13
162 INT170710 Negative_regulation of Siah1a 1 0.43 0.1 0.12
163 INT133486 Negative_regulation of Binding of BAX 1 0.15 0.62 0.12
164 INT170701 Negative_regulation of Localization of Siah1a 1 0.42 0 0.11
165 INT336888 Negative_regulation of Transcription of Bax 1 0.07 0.68 0.11
166 INT170696 Localization of Siah1a 1 0.74 0 0.11
167 INT310906 Regulation of Bcl2l11 2 0.25 2.9 0.1
168 INT170699 Positive_regulation of Siah1a 1 0.50 0.08 0.1
169 INT345504 Binding of PMAIP1 1 0.15 1.7 0.1
170 INT233567 Positive_regulation of Clu 3 0.59 2.91 0.09
171 INT304137 Regulation of Localization of Bax 2 0.24 1.7 0.09
172 INT220491 Transcription of Cav1 2 0.54 1.1 0.07
173 INT303976 Negative_regulation of Protein_catabolism of BAX 1 0.09 0.24 0.07
174 INT220500 Positive_regulation of Transcription of Cav1 1 0.16 0.9 0.07
175 INT303978 Protein_catabolism of BAX 1 0.13 0.24 0.07
176 INT307466 Positive_regulation of Phosphorylation of Bax 1 0.15 0.76 0.07
177 INT344260 Localization of BCL2L11 2 0.11 2.41 0.06
178 INT170698 Regulation of Siah1a 1 0.45 0.36 0.06
179 INT170704 Negative_regulation of Binding of Siah1a 1 0.42 0 0.06
180 INT233554 Negative_regulation of Gene_expression of Clu 2 0.39 1.96 0.05
181 INT233550 Localization of Clu 2 0.69 4.52 0.05
182 INT220502 Positive_regulation of Positive_regulation of Cav1 1 0.24 0.21 0.05
183 INT268622 Regulation of Negative_regulation of Bax 1 0.12 0.81 0.05
184 INT315009 Regulation of Phosphorylation of Cav1 1 0.36 0.2 0.05
185 INT265487 Positive_regulation of Localization of PMAIP1 1 0.25 1.17 0.05
186 INT352131 Binding of Bcl2l11 1 0.05 4.17 0.05
187 INT309494 Negative_regulation of Binding of Bax 2 0.38 1.31 0.04
188 INT172226 Positive_regulation of Negative_regulation of BAX 2 0.48 1.51 0.04
189 INT300713 Regulation of Localization of Cav1 2 0.42 1.37 0.04
190 INT333238 Negative_regulation of Positive_regulation of Bcl2l11 1 0.15 0.31 0.04
191 INT340387 Regulation of Positive_regulation of Bax 1 0.27 0.61 0.04
192 INT310746 Negative_regulation of Regulation of BAX 1 0.35 1.33 0.04
193 INT314252 Transcription of CAV1 1 0.50 0.07 0.04
194 INT340390 Regulation of Binding of Bax 1 0.54 0.59 0.04
195 INT161524 Regulation of Clu 4 0.38 3.18 0.03
196 INT123525 Phosphorylation of Bax 3 0.41 1.18 0.03
197 INT268313 Regulation of Gene_expression of Bcl2l11 2 0.33 3.88 0.03
198 INT302234 Negative_regulation of Localization of BAX 2 0.24 2.07 0.03
199 INT190723 Gene_expression of Gnb2l1 1 0.17 0 0.03
200 INT238508 Regulation of Regulation of BAX 1 0.21 1.5 0.03
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