GO:GO:0030346

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Name protein phosphatase 2B binding
Categary Function
Go Slim No
Go Link GO:0030346
Unique Molecular Interactions 100
Total Molecular Interactions 120
Total Single Events 1362
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein phosphatase 2B binding. They are ordered first by their pain relevance and then by number of times they were reported for protein phosphatase 2B binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT42579 SOD1 Negative_regulation of POMC 1 0.16 0.43 1.27
2 INT130232 Binding of Cat and Sod1 1 0.35 0.3 0.98
3 INT130231 Positive_regulation of Binding of Cat and Sod1 1 0.46 0.3 0.98
4 INT250959 Binding of HLA-B and SOD1 1 0.05 0.75 0.75
5 INT296097 Acsm3 Negative_regulation of SOD1 1 0.01 1.3 0.72
6 INT5856 Bad Positive_regulation of Gene_expression of Penk 1 0.02 0.37 0.5
7 INT274625 OPN1MW Positive_regulation of SOD1 1 0.19 0.29 0.5
8 INT155958 Binding of Kcnk2 and Akap5 1 0.15 0.64 0.48
9 INT241914 SOD1 Positive_regulation of Ros1 1 0.00 0.76 0.44
10 INT135015 MGP Negative_regulation of Cabin1 1 0.01 0.26 0.4
11 INT235887 CALM1 Regulation of Akap5 1 0.00 0 0.39
12 INT235860 Prkca Regulation of Akap5 1 0.16 0 0.39
13 INT250956 Positive_regulation of Binding of HLA-B and SOD1 1 0.07 0.38 0.38
14 INT324813 Tlr4 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
15 INT324803 Hmgb1 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
16 INT324827 Hmgb1 Positive_regulation of Bad 1 0.02 0.43 0.36
17 INT324808 Tlr4 Positive_regulation of Bad 1 0.02 0.43 0.36
18 INT235861 Binding of Prkaca and Akap5 1 0.20 0 0.35
19 INT235862 Binding of Ppp3r2 and Akap5 1 0.01 0 0.35
20 INT235859 Binding of Prkca and Akap5 1 0.13 0 0.35
21 INT315385 Adcyap1 Positive_regulation of Phosphorylation of Bad 1 0.05 0.44 0.32
22 INT242399 Cyp19a1 Negative_regulation of Gene_expression of Bad 1 0.00 1.32 0.31
23 INT29984 Bad Positive_regulation of Localization of Prl 1 0.15 0 0.3
24 INT135014 Binding of Ephb1 and Cabin1 1 0.09 0.32 0.3
25 INT154194 Binding of KCNK2 and Akap5 1 0.08 0.19 0.29
26 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27
27 INT172901 Binding of Bad and Bcl2l1 3 0.13 6.51 0.27
28 INT305623 Ca2 Positive_regulation of Cabin1 1 0.00 0.27 0.27
29 INT164517 CABIN1 Positive_regulation of Transcription of IL2 1 0.13 0.35 0.22
30 INT120376 Bad Positive_regulation of Gene_expression of Oxtr 1 0.08 0 0.22
31 INT315386 Adcyap1 Positive_regulation of Bad 1 0.03 0.52 0.2
32 INT305508 Binding of Sod1 and Slc17a6 1 0.03 1.1 0.2
33 INT305511 Negative_regulation of Binding of Sod1 and Slc17a6 1 0.03 1.1 0.2
34 INT28562 SOD1 Negative_regulation of Pacs1 1 0.03 2.63 0.19
35 INT251492 Binding of HSPD1 and SOD1 1 0.02 1.45 0.18
36 INT250949 Binding of KIR3DL2 and SOD1 1 0.24 0.55 0.18
37 INT252575 Rpe Negative_regulation of SOD1 1 0.03 2.39 0.14
38 INT240909 Hmgcr Regulation of Gene_expression of Sod1 1 0.03 0.53 0.14
39 INT263321 Akt1 Regulation of Bad 1 0.00 0.74 0.13
40 INT266900 Gene_expression of Sod2 Negative_regulation of Gene_expression of Sod1 1 0.11 0.41 0.11
41 INT274156 Negative_regulation of Cabin1 Negative_regulation of Gene_expression of Vegfa 1 0.08 0.28 0.09
42 INT275184 Bad Positive_regulation of Positive_regulation of Bcl2l1 1 0.12 0.62 0.09
43 INT275183 Bad Positive_regulation of Gene_expression of Bcl2 1 0.08 0.63 0.09
44 INT174133 Binding of Igfals and Sod1 3 0.19 3 0.08
45 INT303337 Binding of SOD1 and Igfals 1 0.06 1.27 0.08
46 INT346695 Negative_regulation of SOD1 Positive_regulation of Negative_regulation of Hist3h2a 1 0.00 0.41 0.08
47 INT31986 NTS Positive_regulation of Binding of SOD1 1 0.16 0 0.08
48 INT220724 Binding of IGFALS and SOD1 1 0.06 2.1 0.06
49 INT262233 Nr1i2 Negative_regulation of SOD1 1 0.03 0.23 0.05
50 INT262230 SOD1 Regulation of Nr1i2 1 0.02 0.3 0.05
51 INT240888 Sod1 Regulation of Gene_expression of Ins1 1 0.08 0.18 0.04
52 INT331153 Akt1 Positive_regulation of Bad 1 0.03 0.92 0.04
53 INT331155 Akt1 Positive_regulation of Binding of Bad 1 0.04 0.93 0.04
54 INT266897 Nfe2l2 Positive_regulation of Sod1 1 0.11 0.19 0.04
55 INT331156 Akt1 Positive_regulation of Phosphorylation of Bad 1 0.02 0.91 0.04
56 INT347416 Tlr4 Negative_regulation of SOD1 1 0.00 0.36 0.04
57 INT240905 Gene_expression of Sod1 Negative_regulation of Phosphorylation of Creb1 1 0.32 0.1 0.03
58 INT240881 Gene_expression of Sod1 Positive_regulation of Phosphorylation of Foxo1 1 0.38 0.07 0.03
59 INT292416 SOD1 Regulation of Cat 1 0.01 0.45 0.03
60 INT293367 Binding of CABIN1 and Ppia 1 0.00 0.19 0.03
61 INT293358 Binding of FKBP1A and CABIN1 1 0.00 0.07 0.03
62 INT240875 Gene_expression of Sod1 Negative_regulation of Gene_expression of Pck1 1 0.33 0.27 0.03
63 INT294293 Binding of RCAN1 and CABIN1 1 0.03 0 0.03
64 INT240876 Gene_expression of Sod1 Negative_regulation of Pck1 1 0.33 0.27 0.03
65 INT303056 Rorb Regulation of Bad 1 0.00 0.52 0.03
66 INT239181 Gene_expression of Gh Negative_regulation of Sod1 1 0.24 0.33 0
67 INT229815 Fos Regulation of Bad 1 0.09 0.31 0
68 INT329340 UCN2 Positive_regulation of SOD1 1 0.02 1.12 0
69 INT333853 Binding of SOD1 and Gtf3a 1 0.00 0 0
70 INT293355 Binding of Fkbp1a and CABIN1 1 0.00 0.12 0
71 INT285909 AKT1 Regulation of Phosphorylation of Bad 1 0.01 0.4 0
72 INT240887 Binding of Sod1 and Gopc 1 0.10 0.08 0
73 INT204320 SOD1 Positive_regulation of Protein_catabolism of ROS1 1 0.06 0.05 0
74 INT335953 Binding of BCL2 and Bad 1 0.14 0.37 0
75 INT333854 Binding of SOD1 and Creb1 1 0.02 0 0
76 INT291716 Binding of SOD1 and Rxra 1 0.21 0 0
77 INT295048 Bad Regulation of RYBP 1 0.00 1.64 0
78 INT172908 Binding of Bad and Bax 1 0.01 1.34 0
79 INT232575 SNRNP70 Regulation of SOD1 1 0.12 0.65 0
80 INT293366 Binding of CABIN1 and Fkbp1a 1 0.00 0.05 0
81 INT201760 Binding of BCL2L1 and Positive_regulation of Bad 1 0.01 0.3 0
82 INT217770 MIR181A1 Regulation of PPP3CB 1 0.00 0.7 0
83 INT335951 Binding of Bad and Tgif2lx1 1 0.00 0.37 0
84 INT229418 Mpo Positive_regulation of Sod1 1 0.20 0.71 0
85 INT240882 Sod1 Positive_regulation of Phosphorylation of Creb1 1 0.31 0.1 0
86 INT229826 Fos Positive_regulation of Sod1 1 0.42 0.38 0
87 INT302672 Gene_expression of Zmat3 Positive_regulation of Sod1 1 0.05 0.05 0
88 INT234164 Binding of Sod1 and Dynll1 1 0.06 1.27 0
89 INT240896 Gene_expression of Sod1 Negative_regulation of Ros1 1 0.12 0.69 0
90 INT347418 Tlr4 Positive_regulation of SOD1 1 0.01 0 0
91 INT186247 CGA Regulation of Gene_expression of SOD1 1 0.01 0.35 0
92 INT240874 Sod1 Negative_regulation of Ros1 1 0.11 0.09 0
93 INT201743 Bad Positive_regulation of Positive_regulation of Bax 1 0.00 0.43 0
94 INT294313 Gene_expression of CABIN1 Positive_regulation of IL11 1 0.03 0.06 0
95 INT347417 Positive_regulation of Tlr4 Positive_regulation of SOD1 1 0.01 0 0
96 INT302671 Zmat3 Positive_regulation of Gene_expression of Sod1 1 0.04 0.3 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein phosphatase 2B binding. They are ordered first by their pain relevance and then by number of times they were reported in protein phosphatase 2B binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52
2 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4
3 INT66460 Negative_regulation of Cabin1 15 0.43 8.98 8.03
4 INT67037 Gene_expression of Sod1 121 0.78 59.32 7.99
5 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91
6 INT13385 Gene_expression of Bad 60 0.76 41.86 6.52
7 INT24889 Negative_regulation of CABIN1 36 0.48 16.76 4.73
8 INT137332 Positive_regulation of Gene_expression of Sod1 41 0.70 19.8 4.69
9 INT33229 Gene_expression of Bad 9 0.70 6.95 4.15
10 INT51654 Regulation of Bad 21 0.40 12.18 4.06
11 INT3437 Negative_regulation of Bad 5 0.48 1.66 2.99
12 INT48539 Positive_regulation of Cabin1 8 0.32 0.63 2.68
13 INT91899 Binding of Sod1 17 0.47 11.56 2.63
14 INT31989 Binding of SOD1 43 0.47 19.38 2.55
15 INT29983 Localization of Bad 5 0.28 4.44 2.52
16 INT24887 Localization of CABIN1 1 0.71 1.19 2.39
17 INT130230 Positive_regulation of Sod1 3 0.67 1.63 2.3
18 INT172874 Phosphorylation of Bad 31 0.80 27.46 2.07
19 INT96764 Positive_regulation of Gene_expression of SOD1 36 0.61 16.55 1.99
20 INT69222 Positive_regulation of Sod1 15 0.61 8.19 1.87
21 INT145655 Transcription of Sod1 3 0.42 0.92 1.84
22 INT69221 Negative_regulation of Sod1 14 0.56 10.57 1.83
23 INT43143 Binding of Bad 8 0.21 5.12 1.81
24 INT24888 Gene_expression of CABIN1 3 0.56 0.91 1.71
25 INT93427 Negative_regulation of Bad 4 0.02 2.5 1.63
26 INT5855 Positive_regulation of Bad 12 0.61 12.26 1.56
27 INT27293 Regulation of SOD1 21 0.53 15.73 1.55
28 INT91900 Localization of Sod1 12 0.77 6.62 1.51
29 INT117101 Gene_expression of Sod1 18 0.67 7.93 1.47
30 INT18495 Regulation of Bad 6 0.19 4.79 1.45
31 INT145658 Negative_regulation of Transcription of Sod1 1 0.34 0.15 1.42
32 INT154081 Negative_regulation of Localization of Bad 2 0.16 2.06 1.31
33 INT132191 Regulation of Cabin1 6 0.45 2.96 1.28
34 INT117100 Positive_regulation of Gene_expression of Sod1 5 0.60 1.18 1.2
35 INT159543 Localization of SOD1 29 0.75 8.62 1.06
36 INT129398 Negative_regulation of Gene_expression of SOD1 22 0.43 7.11 1.02
37 INT126876 Gene_expression of Cabin1 6 0.63 2.81 0.92
38 INT159668 Positive_regulation of Bad 8 0.45 6.32 0.89
39 INT133767 Transcription of Bad 2 0.57 1.72 0.84
40 INT135836 Negative_regulation of Sod1 5 0.25 1.62 0.82
41 INT275180 Positive_regulation of Phosphorylation of Bad 4 0.40 3.79 0.77
42 INT129630 Regulation of Sod1 6 0.44 4.94 0.73
43 INT201628 Positive_regulation of Gene_expression of Bad 12 0.68 13.86 0.72
44 INT28561 Regulation of Gene_expression of SOD1 9 0.61 2.83 0.71
45 INT134276 Positive_regulation of Positive_regulation of Cabin1 1 0.03 0.13 0.65
46 INT331152 Positive_regulation of Localization of Bad 1 0.19 1.35 0.64
47 INT331150 Negative_regulation of Gene_expression of Bad 1 0.10 1.33 0.63
48 INT126877 Positive_regulation of Gene_expression of Cabin1 3 0.56 1.97 0.57
49 INT162429 Negative_regulation of Gene_expression of Sod1 6 0.48 2.46 0.53
50 INT142871 Negative_regulation of Gene_expression of Bad 7 0.51 6.52 0.49
51 INT159667 Negative_regulation of Positive_regulation of Bad 4 0.20 3.13 0.48
52 INT105886 Phosphorylation of Bad 3 0.23 2.15 0.47
53 INT135013 Binding of Cabin1 2 0.32 0.72 0.46
54 INT187472 Regulation of Gene_expression of Sod1 5 0.53 2.68 0.37
55 INT192983 Regulation of Regulation of Bad 1 0.01 0.3 0.33
56 INT48538 Regulation of Positive_regulation of Cabin1 1 0.01 0.28 0.29
57 INT129632 Negative_regulation of Transcription of Sod1 1 0.43 0.69 0.28
58 INT129631 Transcription of Sod1 1 0.52 0.69 0.28
59 INT135807 Positive_regulation of Negative_regulation of Bad 1 0.35 0.24 0.27
60 INT129399 Transcription of SOD1 6 0.66 3.08 0.25
61 INT88004 Binding of CABIN1 2 0.03 0.11 0.25
62 INT220727 Regulation of Binding of SOD1 1 0.42 1.46 0.21
63 INT238309 Negative_regulation of Gene_expression of Sod1 3 0.38 1.09 0.2
64 INT116432 Positive_regulation of Positive_regulation of SOD1 3 0.40 3.88 0.2
65 INT174127 Positive_regulation of Positive_regulation of Sod1 2 0.45 4.9 0.19
66 INT240279 Negative_regulation of Positive_regulation of SOD1 5 0.43 2.45 0.18
67 INT201637 Regulation of Gene_expression of Bad 4 0.23 2.99 0.17
68 INT319180 Regulation of Transcription of SOD1 1 0.21 0.3 0.17
69 INT126875 Negative_regulation of Gene_expression of Cabin1 2 0.47 1.04 0.16
70 INT273054 Positive_regulation of Binding of Bad 2 0.14 2.66 0.16
71 INT238306 Regulation of Gene_expression of Sod1 1 0.39 0.46 0.16
72 INT323165 Regulation of Akap5 1 0.10 0.08 0.14
73 INT204370 Negative_regulation of Binding of SOD1 4 0.41 0.82 0.13
74 INT164520 Regulation of CABIN1 2 0.26 0.1 0.13
75 INT314356 Positive_regulation of Localization of SOD1 1 0.04 0.82 0.13
76 INT153486 Positive_regulation of Gene_expression of Bad 1 0.62 0.74 0.13
77 INT172857 Binding of Bad 2 0.36 2.86 0.12
78 INT229429 Localization of Sod1 2 0.65 0.8 0.12
79 INT217824 Positive_regulation of PPP3CB 2 0.19 1.02 0.11
80 INT294331 Positive_regulation of CABIN1 1 0.03 0 0.11
81 INT204330 Protein_catabolism of SOD1 8 0.84 4.75 0.1
82 INT268725 Positive_regulation of Negative_regulation of SOD1 3 0.35 2.41 0.1
83 INT177582 Regulation of Sod1 2 0.24 0.39 0.1
84 INT162014 Protein_catabolism of Bad 1 0.76 0.29 0.1
85 INT203330 Negative_regulation of Binding of Sod1 1 0.28 1.03 0.1
86 INT274155 Localization of Cabin1 1 0.57 0.55 0.1
87 INT275179 Localization of Bad 2 0.69 0.66 0.09
88 INT252574 Negative_regulation of Regulation of SOD1 1 0.06 1.11 0.09
89 INT342172 Regulation of Regulation of SOD1 1 0.02 0.75 0.08
90 INT274153 Negative_regulation of Binding of Cabin1 1 0.28 0.2 0.08
91 INT323163 Negative_regulation of Akap5 1 0.16 0.1 0.07
92 INT323162 Transcription of Akap5 1 0.19 0.1 0.07
93 INT294336 Negative_regulation of Binding of CABIN1 1 0.03 0 0.07
94 INT272876 Negative_regulation of Localization of Sod1 1 0.18 0.57 0.03
95 INT240277 Negative_regulation of Protein_catabolism of SOD1 1 0.42 1.23 0.03
96 INT294360 Negative_regulation of Gene_expression of CABIN1 1 0.03 0.06 0.03
97 INT250969 Regulation of Positive_regulation of SOD1 2 0.44 0.38 0
98 INT174131 Regulation of Negative_regulation of Sod1 1 0.43 0.52 0
99 INT217815 Gene_expression of PPP3CB 1 0.01 1.07 0
100 INT253184 Binding of Sod1 1 0.33 0.06 0
101 INT268728 Negative_regulation of Negative_regulation of SOD1 1 0.24 0 0
102 INT175515 Regulation of Phosphorylation of Bad 1 0.08 1.69 0
103 INT330030 Positive_regulation of Regulation of Bad 1 0.21 0.71 0
104 INT294330 Positive_regulation of Gene_expression of CABIN1 1 0.03 0.06 0
105 INT174130 Positive_regulation of Binding of Sod1 1 0.48 0.72 0
106 INT335937 Negative_regulation of Phosphorylation of Bad 1 0.15 0.41 0
107 INT118577 Positive_regulation of Binding of SOD1 1 0.28 0.16 0
108 INT217840 Regulation of PPP3CB 1 0.00 0.74 0
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