GO:GO:0048844

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Name artery morphogenesis
Categary Process
Go Slim No
Go Link GO:0048844
Unique Molecular Interactions 752
Total Molecular Interactions 1159
Total Single Events 9283
Pain Genes Associated 26

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for artery morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for artery morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT134215 CRH Positive_regulation of ENG 1 0.13 1.22 2.06
2 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
3 INT31445 ENG Positive_regulation of Localization of Prl 4 0.01 0 1.77
4 INT167321 Binding of ENG and OPRM1 1 0.27 0.63 1.76
5 INT199503 ENG Positive_regulation of Oprk1 1 0.01 0.87 1.69
6 INT45306 Pomc Positive_regulation of ENG 2 0.07 1.11 1.68
7 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68
8 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
9 INT45307 ENG Positive_regulation of Localization of Avp 1 0.00 0 1.45
10 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
11 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
12 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
13 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
14 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
15 INT31444 ENG Positive_regulation of Prl 1 0.01 0 1.14
16 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
17 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
18 INT221 Chd7 Negative_regulation of Th 1 0.02 0 1.04
19 INT134213 CRH Positive_regulation of Gene_expression of ENG 1 0.13 0.61 1.03
20 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
21 INT161231 Positive_regulation of Htr1a Positive_regulation of Gene_expression of VEGFA 1 0.67 0.16 0.95
22 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
23 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
24 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
25 INT32187 Binding of ENG and Negative_regulation of Localization of LH 1 0.01 0 0.91
26 INT291011 Pomc Regulation of Gene_expression of ENG 1 0.08 0.86 0.91
27 INT74872 Igh-Dex Positive_regulation of Chd7 1 0.01 0.5 0.89
28 INT297332 Apoe Negative_regulation of Gene_expression of Mpz 1 0.02 1.09 0.87
29 INT116108 VEGFA Positive_regulation of SEC23IP 1 0.10 0.3 0.83
30 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
31 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
32 INT208354 Binding of Apoe and Hdl1 12 0.13 8.37 0.77
33 INT161951 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 0.27 0.99 0.76
34 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
35 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74
36 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73
37 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73
38 INT161950 TGFBR1 Negative_regulation of Localization of Ngf 1 0.23 1.01 0.72
39 INT120018 VEGFA Positive_regulation of CCL3 1 0.01 1 0.7
40 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
41 INT120036 VEGFA Positive_regulation of Prap1 1 0.00 1 0.7
42 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
43 INT167355 VEGFA Regulation of RYBP 1 0.01 0.53 0.68
44 INT168295 PROC Regulation of Gene_expression of VEGFA 2 0.00 1.6 0.67
45 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
46 INT214595 Binding of FOXC1 and TIMP1 1 0.02 0.96 0.66
47 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
48 INT32719 ENG Regulation of LH 2 0.00 0 0.64
49 INT31443 ENG Positive_regulation of Localization of Pomc 1 0.00 0 0.63
50 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63
51 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
52 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61
53 INT224731 Binding of VEGFA and Cia1 1 0.01 0.91 0.61
54 INT224733 Negative_regulation of Binding of VEGFA and Cia1 1 0.01 0.91 0.61
55 INT98629 VEGFA Positive_regulation of Gene_expression of EGR1 1 0.52 0.42 0.61
56 INT98628 VEGFA Positive_regulation of Transcription of EGR1 1 0.52 0.42 0.61
57 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
58 INT145661 Ptger2 Positive_regulation of Gene_expression of VEGFA 4 0.27 2.73 0.6
59 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
60 INT299286 VEGFA Positive_regulation of PI3 1 0.16 0.46 0.6
61 INT342624 VEGFA Negative_regulation of Mmp2 1 0.09 1.54 0.58
62 INT327339 Gtf3a Positive_regulation of VEGFA 1 0.00 2.34 0.58
63 INT297331 Apoe Negative_regulation of Gene_expression of Il6 1 0.14 0.61 0.57
64 INT304326 Ptger1 Positive_regulation of Gene_expression of VEGFA 1 0.19 1.37 0.57
65 INT342621 VEGFA Negative_regulation of Timp2 1 0.09 1.53 0.57
66 INT134214 CRH Regulation of Localization of ENG 1 0.14 0.39 0.53
67 INT32151 ENG Positive_regulation of Gene_expression of IFNA1 1 0.37 0 0.53
68 INT32291 ENG Negative_regulation of LH 2 0.00 0 0.52
69 INT254761 Igh-Dex Positive_regulation of Apoe 1 0.00 0.08 0.52
70 INT194918 Csf2 Positive_regulation of Gene_expression of VEGFA 1 0.02 0.85 0.52
71 INT194919 Kitl Positive_regulation of Gene_expression of VEGFA 1 0.01 0.85 0.52
72 INT302644 ARSA Positive_regulation of Gene_expression of TGFBR1 1 0.04 0.29 0.51
73 INT302647 ARSA Positive_regulation of TGFBR1 1 0.03 0.29 0.51
74 INT30618 Slc3a1 Regulation of ENG 1 0.00 0 0.5
75 INT30619 Pomc Regulation of ENG 1 0.00 0 0.5
76 INT116862 Apoe Positive_regulation of Il10 1 0.30 0.69 0.5
77 INT127430 VEGFA Negative_regulation of Gene_expression of TIMP1 1 0.43 0.6 0.5
78 INT116863 Apoe Negative_regulation of Hand1 1 0.37 0.69 0.5
79 INT254768 DNMT1 Positive_regulation of Gene_expression of Apoe 1 0.02 0.05 0.49
80 INT102214 ENG Negative_regulation of HP 1 0.01 0 0.49
81 INT60872 Binding of ENG and Abat 1 0.00 0 0.49
82 INT60871 ENG Regulation of Localization of LH 1 0.00 0 0.49
83 INT327332 VEGFA Positive_regulation of Gene_expression of Hgfac 1 0.00 2.02 0.49
84 INT288376 IL17A Regulation of VEGFA 1 0.00 1.16 0.49
85 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48
86 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48
87 INT305547 VEGFA Positive_regulation of Gtf3a 2 0.00 1.83 0.48
88 INT260836 Il18 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.48
89 INT331928 Negative_regulation of Cpox Negative_regulation of VEGFA 1 0.01 0.97 0.47
90 INT43695 ENG Regulation of Regulation of Prl 1 0.00 0 0.47
91 INT314053 VEGFA Positive_regulation of Gene_expression of Mmp2 1 0.02 0.2 0.47
92 INT60870 ENG Negative_regulation of Localization of LH 1 0.00 0 0.47
93 INT260843 Il6 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
94 INT260838 Il17a Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
95 INT102213 Binding of ENG and HP 1 0.01 0 0.47
96 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46
97 INT224698 Il17a Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
98 INT224699 Il18 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
99 INT224451 Il1 Positive_regulation of Gene_expression of VEGFA 1 0.10 1.08 0.45
100 INT142608 Apoe Regulation of Gene_expression of Il6 1 0.25 1.01 0.44
101 INT224434 TNF Positive_regulation of VEGFA 1 0.10 2.04 0.44
102 INT311587 CXCL10 Regulation of Gene_expression of VEGFA 1 0.23 0.45 0.43
103 INT353109 Binding of VEGFA and Aes 1 0.02 3.93 0.43
104 INT311589 EGF Regulation of Gene_expression of VEGFA 1 0.18 0.51 0.43
105 INT254350 FASLG Negative_regulation of Gene_expression of VEGFA 1 0.06 0.92 0.42
106 INT202516 Positive_regulation of Binding of ENG and Penk 1 0.03 0.58 0.42
107 INT254760 Igh-Dex Positive_regulation of Gene_expression of Apoe 1 0.00 0 0.42
108 INT329085 Csf2 Positive_regulation of Apoe 1 0.00 1.23 0.42
109 INT202515 Binding of ENG and Penk 1 0.02 0.57 0.41
110 INT153720 Binding of VEGFA and Pscs 1 0.32 3.12 0.41
111 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
112 INT32720 Negative_regulation of ENG Regulation of LH 1 0.00 0 0.41
113 INT295709 PTGER2 Regulation of VEGFA 1 0.01 1.61 0.41
114 INT304319 Ptger1 Positive_regulation of Gene_expression of Vegfa 1 0.37 1.19 0.39
115 INT285205 Binding of VEGFA and SLEB1 1 0.05 5.12 0.38
116 INT291616 Cby1 Positive_regulation of Gene_expression of Smad7 1 0.00 0.79 0.38
117 INT240617 Binding of APOB and ADIPOQ 1 0.04 3.62 0.38
118 INT342623 Binding of VEGFA and Col18a1 1 0.02 1.15 0.37
119 INT342606 Binding of MMP14 and VEGFA 1 0.08 1.16 0.37
120 INT277353 VEGFA Regulation of Mtor 1 0.02 1.11 0.37
121 INT277355 VEGFA Regulation of Trerf1 1 0.08 1.17 0.37
122 INT277354 Gene_expression of VEGFA Regulation of Mtor 1 0.02 1.1 0.37
123 INT277352 Gene_expression of VEGFA Regulation of Trerf1 1 0.08 1.16 0.37
124 INT329449 IL17A Regulation of Gene_expression of Vegfa 1 0.28 0.63 0.36
125 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35
126 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34
127 INT352231 VEGFA Negative_regulation of Cntf 1 0.04 0.22 0.34
128 INT352230 VEGFA Negative_regulation of Gene_expression of Cntf 1 0.04 0.22 0.34
129 INT352232 VEGFA Negative_regulation of Vegfa 1 0.02 0.21 0.34
130 INT110691 Lta Positive_regulation of Gene_expression of VEGFA 1 0.24 0.48 0.33
131 INT295717 VEGFA Regulation of MMP9 1 0.01 0.98 0.33
132 INT329448 IL17A Positive_regulation of Gene_expression of Vegfa 1 0.45 0.59 0.32
133 INT128756 Binding of Esr1 and Foxc1 1 0.01 0.43 0.32
134 INT191616 Binding of Cbln1 and Nf1 1 0.01 0.2 0.32
135 INT191620 Binding of Nf1 and Gopc 1 0.08 0.2 0.32
136 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3
137 INT191611 Nf1 Regulation of ras 1 0.26 0.18 0.3
138 INT229635 SPINK5 Positive_regulation of NF1 1 0.01 2.17 0.3
139 INT55404 Binding of ENG and Th 1 0.02 0 0.3
140 INT210953 Binding of VEGFA and Csf2 1 0.00 0.47 0.3
141 INT281797 Positive_regulation of Chrna4 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.43 0.3
142 INT266800 Dlst Positive_regulation of Localization of VEGFA 1 0.02 0.88 0.29
143 INT29137 ENG Regulation of POMC 1 0.00 0 0.28
144 INT254759 Igh-Dex Positive_regulation of Localization of Apoe 1 0.00 0.32 0.28
145 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28
146 INT214615 FOXC1 Positive_regulation of Gene_expression of Ang 1 0.01 0.29 0.28
147 INT29139 ENG Regulation of Oprl1 1 0.00 0 0.28
148 INT254353 Binding of VEGFA and MMRN1 1 0.00 0.81 0.28
149 INT214594 Binding of FOXC1 and IBD9 1 0.00 1.81 0.28
150 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27
151 INT320794 Binding of VEGFA and Flt4 4 0.08 3.04 0.27
152 INT103156 Tnf Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.94 0.27
153 INT287699 TNF Regulation of Binding of VEGFA 1 0.02 0.46 0.27
154 INT297338 Apoe Regulation of Gnb5 1 0.06 1.12 0.27
155 INT318551 Binding of VEGFA and Adamts1 1 0.13 1.13 0.27
156 INT285238 EGF Positive_regulation of VEGFA 1 0.01 1.55 0.27
157 INT141635 Binding of APOB and Alb 1 0.02 0.3 0.26
158 INT248318 RETN Regulation of VEGFA 1 0.00 0.43 0.26
159 INT311918 Insrr Negative_regulation of Tgfbr1 1 0.00 0.87 0.26
160 INT32156 Binding of ENG and Oprd1 1 0.00 0 0.26
161 INT109538 Lox Negative_regulation of Transcription of VEGFA 1 0.30 0.69 0.26
162 INT260423 IFNA1 Positive_regulation of Gene_expression of VEGFA 1 0.01 1.28 0.26
163 INT32149 Binding of ENG and LLGL1 1 0.11 0 0.26
164 INT311902 Acvrl1 Negative_regulation of Tgfbr1 1 0.13 0.87 0.26
165 INT254359 IL1B Positive_regulation of Localization of VEGFA 1 0.01 0.87 0.26
166 INT103152 TNF Positive_regulation of Positive_regulation of VEGFA 1 0.09 0.93 0.26
167 INT126886 Protein_catabolism of SP1 Negative_regulation of Gene_expression of VEGFA 1 0.03 0.49 0.26
168 INT126887 Protein_catabolism of SP4 Negative_regulation of Gene_expression of VEGFA 1 0.15 0.49 0.26
169 INT266803 Dlst Positive_regulation of VEGFA 1 0.01 0.96 0.25
170 INT109539 Lox Negative_regulation of VEGFA 1 0.40 0.68 0.25
171 INT145660 Zfp329 Positive_regulation of Gene_expression of VEGFA 1 0.00 0.51 0.25
172 INT241401 VEGFA Positive_regulation of Gene_expression of Gopc 1 0.11 0.85 0.25
173 INT256227 Binding of EDN1 and VEGFA 1 0.18 2.92 0.25
174 INT254772 DNMT1 Positive_regulation of Apoe 1 0.02 0 0.25
175 INT78293 Binding of Apoe and Ldlr 1 0.20 0.25 0.24
176 INT98631 Negative_regulation of VEGFA Positive_regulation of EGR1 1 0.44 0.18 0.24
177 INT78295 Binding of Ptpra and Apoe 1 0.42 0.25 0.24
178 INT297334 Gnb5 Regulation of Apoe 1 0.09 0.83 0.24
179 INT78294 Negative_regulation of Binding of Ptpra and Apoe 1 0.48 0.25 0.24
180 INT98630 VEGFA Positive_regulation of EGR1 1 0.52 0.18 0.24
181 INT254773 PPARA Positive_regulation of Gene_expression of Apoe 1 0.01 0.07 0.24
182 INT78292 Negative_regulation of Binding of Apoe and Ldlr 1 0.23 0.25 0.24
183 INT43713 ENG Regulation of Prl 1 0.00 0 0.23
184 INT304323 VEGFA Positive_regulation of Gene_expression of Ptger2 1 0.27 0.16 0.23
185 INT118840 VEGFA Regulation of Positive_regulation of Mb 1 0.05 0.36 0.23
186 INT311911 Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
187 INT163403 VEGFA Positive_regulation of MMP2 1 0.52 0.13 0.23
188 INT323436 VEGFA Regulation of Kdr 1 0.03 0.77 0.23
189 INT254774 DNMT1 Positive_regulation of Localization of Apoe 1 0.01 0.31 0.23
190 INT304321 Ptger4 Positive_regulation of Gene_expression of VEGFA 1 0.27 0.59 0.23
191 INT304324 VEGFA Positive_regulation of Gene_expression of Ptger4 1 0.27 0.16 0.23
192 INT245866 Binding of VEGFA and Fgf1 1 0.07 0.52 0.22
193 INT118838 Gene_expression of Vegfa Positive_regulation of Gene_expression of Mb 1 0.44 0.4 0.22
194 INT318189 MUC5AC Regulation of Gene_expression of VEGFA 1 0.21 1.17 0.22
195 INT137611 Crh Positive_regulation of Vegfa 1 0.43 0.49 0.21
196 INT116467 Vegfa Positive_regulation of Akt1 1 0.33 1.41 0.21
197 INT137612 Crh Positive_regulation of Positive_regulation of Vegfa 1 0.43 0.43 0.21
198 INT114837 Il1b Negative_regulation of Vegfa 1 0.26 3.04 0.21
199 INT163096 Tlr2 Positive_regulation of Gene_expression of VEGFA 1 0.07 0.16 0.21
200 INT116469 VEGFA Positive_regulation of Amfr 1 0.01 1.39 0.21

Single Events

The table below shows the top 100 pain related interactions that have been reported for artery morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in artery morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
2 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
3 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
4 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
5 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
6 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6
7 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69
8 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
9 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
10 INT10799 Localization of ENG 63 0.78 18.67 27.28
11 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26
12 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
13 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
14 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
15 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89
16 INT7674 Regulation of ENG 42 0.30 11.41 14.44
17 INT7673 Negative_regulation of ENG 31 0.42 7.9 8.61
18 INT39301 Gene_expression of Chd7 50 0.26 27.06 8.13
19 INT197493 Localization of Apoe 61 0.79 27.48 7.06
20 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94
21 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72
22 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63
23 INT23375 Binding of ENG 17 0.47 6.02 6.46
24 INT63042 Binding of Apoe 59 0.48 31.23 5.88
25 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88
26 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78
27 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9
28 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79
29 INT55758 Positive_regulation of Apoe 15 0.70 11.71 4.69
30 INT68216 Binding of NF1 40 0.48 51.24 4.59
31 INT37912 Negative_regulation of Chd7 10 0.26 5.84 4.46
32 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22
33 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17
34 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95
35 INT118835 Positive_regulation of Vegfa 18 0.59 11.2 3.91
36 INT15033 Gene_expression of Apoe 18 0.78 14.97 3.75
37 INT104624 Negative_regulation of Apoe 26 0.59 19.25 3.71
38 INT120072 Gene_expression of Smad7 38 0.74 20.87 3.69
39 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52
40 INT15844 Positive_regulation of Localization of ENG 7 0.67 4.2 3.47
41 INT72141 Binding of Apoe 11 0.37 10.91 3.27
42 INT99687 Negative_regulation of Transcription of VEGFA 17 0.43 10.3 3.25
43 INT111547 Negative_regulation of Phosphorylation of VEGFA 13 0.42 5.08 3.22
44 INT97710 Localization of Apoe 1 0.79 7.18 3.2
45 INT75484 Gene_expression of Tgfbr1 21 0.64 13.36 3.15
46 INT137609 Localization of Vegfa 22 0.78 14.67 3.01
47 INT32222 Negative_regulation of Gene_expression of ENG 9 0.37 2.23 2.89
48 INT50080 Binding of APOE 38 0.45 29.61 2.67
49 INT43719 Positive_regulation of Vegfa 21 0.69 5.15 2.64
50 INT22071 Positive_regulation of Gene_expression of ENG 13 0.50 5.44 2.62
51 INT97713 Negative_regulation of Apoe 4 0.59 4.57 2.52
52 INT77852 Binding of Chd7 8 0.31 4.1 2.51
53 INT113164 Regulation of Regulation of VEGFA 6 0.36 5.96 2.43
54 INT61434 Regulation of Nf1 3 0.26 1.39 2.4
55 INT13997 Regulation of Gene_expression of ENG 11 0.36 3.31 2.31
56 INT123528 Negative_regulation of Gene_expression of Vegfa 10 0.57 7.08 2.31
57 INT64700 Binding of Nf1 14 0.45 15.24 2.29
58 INT43723 Regulation of Vegfa 9 0.34 4.96 2.28
59 INT208344 Positive_regulation of Localization of Apoe 22 0.48 9.6 2.27
60 INT12133 Regulation of Localization of ENG 3 0.03 0.57 2.24
61 INT142265 Regulation of Apoe 20 0.60 9.52 2.23
62 INT105247 Positive_regulation of Gene_expression of Vegfa 12 0.67 12.07 2.05
63 INT84060 Regulation of Apoe 4 0.62 3.33 2.05
64 INT136818 Positive_regulation of Phosphorylation of VEGFA 4 0.46 0.81 2.02
65 INT184676 Transcription of Prrx2 1 0.37 3.64 2.02
66 INT32135 Positive_regulation of Positive_regulation of ENG 2 0.02 0.98 1.99
67 INT80798 Positive_regulation of Chd7 16 0.14 7.95 1.95
68 INT84510 Positive_regulation of Nf1 8 0.69 9.52 1.93
69 INT122195 Regulation of Localization of VEGFA 13 0.57 10.61 1.92
70 INT68181 Binding of Nf1 6 0.48 8.14 1.88
71 INT40877 Positive_regulation of APOB 35 0.68 32.47 1.86
72 INT174924 Gene_expression of Smad7 6 0.41 3.59 1.76
73 INT174923 Positive_regulation of Gene_expression of Smad7 3 0.37 2.3 1.73
74 INT15845 Negative_regulation of Localization of ENG 3 0.05 0.76 1.71
75 INT118833 Positive_regulation of Gene_expression of Vegfa 11 0.65 8.14 1.7
76 INT12442 Localization of Vegfa 11 0.73 4.85 1.68
77 INT96814 Negative_regulation of APOE 13 0.59 10.64 1.61
78 INT105248 Negative_regulation of Vegfa 8 0.47 6.19 1.61
79 INT9466 Binding of APOB 27 0.41 19.36 1.56
80 INT89116 Regulation of Positive_regulation of VEGFA 8 0.43 6.62 1.5
81 INT184683 Gene_expression of Prrx2 1 0.37 7.9 1.5
82 INT217388 Negative_regulation of Gene_expression of Apoe 11 0.59 6.07 1.4
83 INT109536 Negative_regulation of Vegfa 15 0.46 10.35 1.39
84 INT113960 Positive_regulation of Gene_expression of APOB 8 0.49 5.88 1.39
85 INT37799 Gene_expression of Apob 13 0.56 10.59 1.36
86 INT97716 Transcription of Apoe 3 0.53 2.61 1.36
87 INT20238 Regulation of APOB 9 0.61 11.52 1.26
88 INT120076 Positive_regulation of Gene_expression of Smad7 16 0.65 11.33 1.25
89 INT32717 Negative_regulation of Regulation of ENG 3 0.00 0.43 1.25
90 INT90938 Gene_expression of Eng 48 0.72 15.76 1.24
91 INT131645 Negative_regulation of Nf1 10 0.58 8.12 1.24
92 INT61993 Gene_expression of NF1 29 0.78 34.47 1.23
93 INT97715 Regulation of Gene_expression of Apoe 3 0.62 1.98 1.23
94 INT113336 Positive_regulation of Gene_expression of Apoe 3 0.70 1.79 1.23
95 INT39711 Negative_regulation of FOXC1 4 0.41 4.29 1.2
96 INT81311 Gene_expression of FOXC1 9 0.44 3.46 1.18
97 INT137607 Positive_regulation of Localization of Vegfa 7 0.49 3.72 1.18
98 INT188376 Negative_regulation of Gene_expression of Vegfa 5 0.30 5.29 1.18
99 INT310164 Negative_regulation of Gene_expression of Tgfbr1 9 0.40 6.11 1.17
100 INT51863 Negative_regulation of Negative_regulation of ENG 2 0.04 0.51 1.13
101 INT156427 Localization of FOXC1 2 0.73 1.36 1.07
102 INT217390 Negative_regulation of Positive_regulation of Apoe 3 0.37 1.95 1.05
103 INT184698 Positive_regulation of Prrx2 1 0.38 3.21 1.01
104 INT214609 Positive_regulation of Gene_expression of FOXC1 1 0.08 1.78 1
105 INT37914 Regulation of Negative_regulation of Chd7 1 0.12 0 1
106 INT112717 Negative_regulation of Binding of VEGFA 21 0.56 11.07 0.99
107 INT46334 Binding of FOXC1 2 0.36 2.66 0.99
108 INT43131 Regulation of FOXC1 3 0.36 1.09 0.98
109 INT97714 Negative_regulation of Localization of Apoe 1 0.58 1.83 0.97
110 INT10827 Gene_expression of Apob 16 0.78 13.08 0.9
111 INT9467 Negative_regulation of APOB 14 0.57 10.49 0.88
112 INT265313 Positive_regulation of Tgfbr1 8 0.66 2.95 0.87
113 INT11949 Negative_regulation of Apob 11 0.09 8.13 0.85
114 INT10828 Regulation of Apob 7 0.39 7.55 0.83
115 INT211488 Regulation of Binding of VEGFA 5 0.43 3.72 0.83
116 INT258932 Positive_regulation of TBX1 3 0.39 2.73 0.82
117 INT142597 Regulation of Binding of Apoe 1 0.34 2.21 0.8
118 INT173082 Positive_regulation of Binding of VEGFA 20 0.48 11.16 0.79
119 INT51739 Negative_regulation of Apob 9 0.42 4.21 0.78
120 INT196325 Positive_regulation of Gene_expression of Chd7 7 0.14 4.28 0.76
121 INT161947 Positive_regulation of TGFBR1 2 0.52 1.6 0.76
122 INT197495 Negative_regulation of Localization of Apoe 6 0.43 2.19 0.73
123 INT44612 Positive_regulation of APOE 16 0.67 5.73 0.72
124 INT143445 Protein_catabolism of VEGFA 12 0.85 4.14 0.72
125 INT272878 Negative_regulation of Smad7 4 0.41 3.86 0.72
126 INT12443 Regulation of Localization of Vegfa 2 0.20 0 0.72
127 INT169421 Positive_regulation of FOXC1 4 0.49 2.42 0.7
128 INT270428 Negative_regulation of Binding of APOE 2 0.41 1.16 0.7
129 INT113335 Regulation of Transcription of Apoe 1 0.27 0.51 0.7
130 INT68179 Gene_expression of Nf1 9 0.78 8.87 0.68
131 INT179133 Localization of Nf1 2 0.80 2.18 0.68
132 INT49650 Gene_expression of Nf1 4 0.76 3.38 0.67
133 INT175580 Localization of APOE 10 0.76 18.84 0.65
134 INT11763 Positive_regulation of Regulation of ENG 1 0.01 0.97 0.64
135 INT340625 Protein_catabolism of Vegfa 1 0.05 1.61 0.64
136 INT264709 Gene_expression of Hes1 24 0.76 7.04 0.63
137 INT174868 Regulation of Negative_regulation of VEGFA 4 0.43 4.51 0.63
138 INT97708 Regulation of Localization of Apoe 1 0.61 2.06 0.62
139 INT90939 Positive_regulation of Eng 9 0.64 4.62 0.57
140 INT144922 Gene_expression of TGFBR1 4 0.72 0.19 0.57
141 INT113334 Positive_regulation of Positive_regulation of Apoe 1 0.50 0.6 0.56
142 INT174873 Regulation of Transcription of VEGFA 8 0.43 3.71 0.55
143 INT172964 Binding of Vegfa 14 0.47 10.62 0.53
144 INT105677 Binding of Vegfa 7 0.37 5.22 0.51
145 INT197322 Protein_catabolism of Apoe 6 0.71 3.52 0.51
146 INT61992 Positive_regulation of Gene_expression of NF1 3 0.50 4.47 0.51
147 INT120074 Regulation of Gene_expression of Smad7 1 0.58 2.05 0.5
148 INT100698 Regulation of Chd7 6 0.34 1.85 0.49
149 INT217370 Phosphorylation of Apoe 2 0.63 1.8 0.49
150 INT37800 Positive_regulation of Apob 7 0.18 11.01 0.48
151 INT316933 Transcription of Nf1 1 0.18 0.49 0.47
152 INT316939 Positive_regulation of Transcription of Nf1 1 0.16 0.49 0.47
153 INT96816 Regulation of APOE 8 0.45 6.62 0.44
154 INT74864 Negative_regulation of Gene_expression of Chd7 1 0.08 0.34 0.44
155 INT247568 Negative_regulation of Negative_regulation of VEGFA 5 0.41 5.35 0.43
156 INT159221 Negative_regulation of TBX1 4 0.41 4.22 0.43
157 INT224538 Negative_regulation of Gene_expression of Smad7 1 0.09 0.25 0.43
158 INT268877 Regulation of Gene_expression of Vegfa 2 0.58 4.73 0.42
159 INT152023 Regulation of Vegfa 4 0.52 3.99 0.41
160 INT284164 Localization of Chd7 3 0.25 1.32 0.41
161 INT65606 Binding of TBX1 2 0.30 3.13 0.41
162 INT43720 Regulation of Positive_regulation of Vegfa 1 0.03 0.41 0.41
163 INT43722 Positive_regulation of Regulation of Vegfa 1 0.06 0.41 0.41
164 INT97712 Negative_regulation of Transcription of Apoe 1 0.43 1.05 0.4
165 INT292484 Negative_regulation of TGFBR1 3 0.19 0.75 0.39
166 INT129849 Positive_regulation of Localization of Vegfa 1 0.46 0.35 0.39
167 INT254816 Negative_regulation of Tgfbr1 20 0.55 9.24 0.34
168 INT112334 Regulation of NF1 18 0.52 15.85 0.34
169 INT339386 Negative_regulation of Gene_expression of Apob 3 0.43 1.91 0.34
170 INT131542 Negative_regulation of Gene_expression of APOE 6 0.40 3.92 0.33
171 INT128754 Binding of Foxc1 1 0.01 0.43 0.32
172 INT134840 Gene_expression of SMAD7 1 0.74 2.74 0.31
173 INT83352 Positive_regulation of Negative_regulation of APOB 1 0.01 0.69 0.31
174 INT311128 Positive_regulation of Regulation of Apoe 1 0.30 0.3 0.3
175 INT175687 Transcription of Apoe 4 0.72 2.12 0.29
176 INT96815 Regulation of Gene_expression of APOE 2 0.62 1.1 0.29
177 INT184716 Binding of Smad7 2 0.34 0.91 0.29
178 INT311881 Regulation of Positive_regulation of Tgfbr1 1 0.22 0.97 0.29
179 INT272890 Regulation of Negative_regulation of Smad7 1 0.19 1.33 0.29
180 INT269082 Gene_expression of TBX1 1 0.14 0.36 0.28
181 INT224619 Regulation of Positive_regulation of Vegfa 1 0.05 0.57 0.27
182 INT224638 Positive_regulation of Positive_regulation of Vegfa 1 0.06 0.57 0.27
183 INT97711 Positive_regulation of Transcription of Apoe 1 0.46 1.06 0.27
184 INT148796 Regulation of Phosphorylation of VEGFA 3 0.35 1.66 0.26
185 INT109537 Transcription of Vegfa 2 0.44 1.32 0.26
186 INT254756 Regulation of Positive_regulation of Apoe 1 0.20 0.22 0.26
187 INT214611 Positive_regulation of Localization of FOXC1 1 0.07 0.34 0.26
188 INT184670 Localization of Prrx2 1 0.35 0.23 0.24
189 INT184671 Positive_regulation of Localization of Prrx2 1 0.24 0.23 0.24
190 INT137608 Regulation of Localization of Vegfa 1 0.25 0.56 0.24
191 INT228793 Negative_regulation of Gene_expression of Smad7 5 0.25 2.33 0.23
192 INT306427 Localization of TBX1 1 0.20 1.08 0.23
193 INT129342 Positive_regulation of Positive_regulation of Nf1 1 0.50 0.79 0.23
194 INT306428 Positive_regulation of Localization of TBX1 1 0.14 1.08 0.23
195 INT68180 Regulation of Nf1 2 0.27 2.02 0.22
196 INT194472 Positive_regulation of Gene_expression of Apob 2 0.15 1.71 0.22
197 INT323964 Negative_regulation of Binding of Apoe 1 0.39 0.35 0.22
198 INT198892 Regulation of Binding of Apoe 6 0.45 2.94 0.21
199 INT177938 Negative_regulation of NF1 9 0.43 10.3 0.2
200 INT206159 Negative_regulation of Regulation of VEGFA 3 0.24 2.38 0.2
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