GO:GO:0051092

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Name positive regulation of NF-kappaB transcription factor activity
Categary Process
Go Slim No
Go Link GO:0051092
Unique Molecular Interactions 4697
Total Molecular Interactions 6961
Total Single Events 55046
Pain Genes Associated 141

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of NF-kappaB transcription factor activity. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of NF-kappaB transcription factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
2 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62
3 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49
4 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1
5 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
6 INT140935 Binding of Cd40lg and Cd40 1 0.30 6.34 5.61
7 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
8 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
9 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
10 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
11 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
12 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
13 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
14 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01
15 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
16 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
17 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
18 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
19 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
20 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11
21 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
22 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
23 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
24 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
25 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
26 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
27 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81
28 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
29 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
30 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
31 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
32 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
33 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
34 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
35 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
36 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
37 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
38 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
39 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
40 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
41 INT251164 Binding of Clu and Trpv1 1 0.19 0.44 2.23
42 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
43 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
44 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
45 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
46 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
47 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
48 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
49 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
50 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
51 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
52 INT184262 Binding of AGER and HMGB1 1 0.34 4.49 2.17
53 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
54 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
55 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
56 INT63918 Binding of Cck and Ripk2 1 0.28 0 2.07
57 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
58 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
59 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
60 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
61 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2
62 INT317540 Camk2a Negative_regulation of Oprm1 1 0.19 0 1.98
63 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
64 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
65 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
66 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
67 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
68 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
69 INT264947 Binding of POMC and TLR2 1 0.03 0.89 1.95
70 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
71 INT83418 Binding of OPRL1 and Ntrk1 1 0.02 0 1.91
72 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
73 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
74 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
75 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
76 INT81914 Binding of HSF1 and NFKB1 1 0.05 1.54 1.85
77 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
78 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83
79 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
80 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
81 INT116092 TFF2 Positive_regulation of NFKB1 1 0.17 0.06 1.77
82 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
83 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
84 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
85 INT119413 SEMA6A Positive_regulation of TNFRSF11A 1 0.10 2.48 1.7
86 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
87 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
88 INT266391 Binding of Ager and S100a1 1 0.01 5.63 1.69
89 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
90 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
91 INT108385 Binding of Crygs and Ntrk1 1 0.01 0 1.67
92 INT108066 Binding of NTRK1 and Ngf 3 0.33 2.56 1.66
93 INT122428 Binding of Ighm and Prkci 1 0.00 0 1.66
94 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
95 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
96 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
97 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
98 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
99 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
100 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
101 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
102 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
103 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
104 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57
105 INT116093 OPRM1 Positive_regulation of Positive_regulation of NFKB1 1 0.36 0.08 1.56
106 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
107 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
108 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
109 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
110 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
111 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
112 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
113 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
114 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
115 INT256360 Car2 Positive_regulation of Localization of Rela 1 0.14 0 1.51
116 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
117 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
118 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
119 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
120 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
121 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
122 INT136843 Binding of Camk2a and Nrgn 1 0.47 0 1.47
123 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
124 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
125 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
126 INT83416 Binding of OPRK1 and Ntrk1 1 0.02 0 1.45
127 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
128 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
129 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
130 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
131 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
132 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39
133 INT118980 NTRK1 Positive_regulation of NGF 1 0.56 1.45 1.39
134 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
135 INT82025 Negative_regulation of Binding of Ntrk1 and Ngf 1 0.47 0.64 1.37
136 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
137 INT122430 Negative_regulation of Binding of Ighm and Prkci 1 0.00 0 1.36
138 INT83197 Binding of Ntrk1 and Gdnf 1 0.01 1.05 1.36
139 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
140 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
141 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
142 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
143 INT264327 IL-17 Positive_regulation of Gene_expression of Tnfsf11 1 0.07 3.19 1.33
144 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
145 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
146 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
147 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32
148 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32
149 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
150 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
151 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
152 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
153 INT112961 NGF Positive_regulation of ICAM1 1 0.40 0.96 1.28
154 INT177232 ICAM1 Regulation of Gene_expression of Vcam1 1 0.03 5.52 1.28
155 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
156 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
157 INT42580 CAT Negative_regulation of POMC 1 0.20 0.42 1.26
158 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
159 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
160 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
161 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
162 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
163 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
164 INT151657 Vcam1 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
165 INT151658 F3 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
166 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24
167 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
168 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
169 INT334129 Acsm3 Positive_regulation of Gene_expression of Icam1 1 0.22 2.89 1.22
170 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
171 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
172 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
173 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
174 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
175 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
176 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
177 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
178 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
179 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
180 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
181 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
182 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2
183 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
184 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
185 INT131462 NGF Regulation of Localization of INS 1 0.40 0.97 1.2
186 INT108067 Negative_regulation of Binding of NTRK1 and Ngf 1 0.06 2.38 1.2
187 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
188 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
189 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
190 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
191 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18
192 INT351373 Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
193 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
194 INT98908 Binding of NTRK1 and PKLR 1 0.41 1.95 1.18
195 INT351378 Gene_expression of Ngf Positive_regulation of Ntrk1 1 0.35 0.41 1.18
196 INT98906 Positive_regulation of Binding of NTRK1 and PKLR 1 0.56 1.95 1.18
197 INT351377 Gene_expression of Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
198 INT153589 Binding of PRKCI and Oprm1 1 0.06 0 1.17
199 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16
200 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of NF-kappaB transcription factor activity. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of NF-kappaB transcription factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
3 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
4 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
5 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
6 INT6852 Localization of TNF 883 0.81 705.95 270.84
7 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
8 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
9 INT6481 Binding of TNF 624 0.48 510.2 214.82
10 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
11 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
12 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
13 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
14 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
15 INT812 Localization of INS 1026 0.81 515.6 145.31
16 INT9660 Regulation of TNF 363 0.62 312.94 139.99
17 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
18 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
19 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
20 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01
21 INT12082 Localization of IL6 365 0.81 241.78 105.78
22 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
23 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
24 INT10166 Localization of Tnf 237 0.81 153.95 88.64
25 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6
26 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32
27 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71
28 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
29 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
30 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
31 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
32 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
33 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
34 INT6849 Localization of IL1B 229 0.81 112.56 69.63
35 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
36 INT19511 Localization of Il6 212 0.81 118.17 67.67
37 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
38 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
39 INT10706 Regulation of Il6 150 0.62 93.23 62.34
40 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28
41 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
42 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
43 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
44 INT251 Regulation of INS 398 0.62 232.47 55.04
45 INT119528 Positive_regulation of Camk2a 135 0.70 26.13 54.7
46 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
47 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
48 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
49 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71
50 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
51 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
52 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43
53 INT9210 Regulation of IL6 166 0.62 125.61 49.95
54 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
55 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
56 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98
57 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
58 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
59 INT13354 Transcription of TNF 108 0.72 85.81 42.32
60 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
61 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48
62 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
63 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52
64 INT115649 Gene_expression of Camk2a 95 0.78 33.22 38
65 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61
66 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
67 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28
68 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17
69 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55
70 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
71 INT6484 Binding of IL1B 122 0.47 75.84 35.07
72 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79
73 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
74 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66
75 INT114729 Phosphorylation of Camk2a 110 0.82 15.49 33.19
76 INT35406 Localization of Tnf 94 0.81 64.63 31.65
77 INT9347 Localization of Il1b 58 0.81 26.13 31.53
78 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
79 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
80 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
81 INT86437 Binding of IL6 154 0.48 121.22 29.3
82 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29
83 INT56072 Negative_regulation of NFKB1 94 0.59 53.16 28.19
84 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
85 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
86 INT5206 Gene_expression of AR 316 0.78 113.83 27.29
87 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
88 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
89 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
90 INT64185 Gene_expression of TNFRSF11A 131 0.76 75.15 24.73
91 INT151758 Gene_expression of PYCARD 91 0.63 14.54 24.27
92 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
93 INT123386 Negative_regulation of Camk2a 48 0.58 12.57 23.78
94 INT51029 Negative_regulation of Il1b 34 0.57 29.34 23.62
95 INT134651 Binding of TLR4 89 0.48 66.96 23.19
96 INT55170 Gene_expression of NFKB1 97 0.77 52.75 23.04
97 INT16721 Negative_regulation of Cat 56 0.59 44.44 22.84
98 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83
99 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73
100 INT66208 Positive_regulation of Positive_regulation of NFKB1 45 0.68 20.17 22.62
101 INT48081 Localization of Il1b 46 0.80 21.59 22.4
102 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
103 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26
104 INT48312 Gene_expression of NTRK1 72 0.78 38.21 22.24
105 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
106 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
107 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
108 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91
109 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
110 INT96156 Gene_expression of Cd40 144 0.77 56.95 21.7
111 INT48407 Positive_regulation of Gene_expression of Icam1 61 0.70 57.91 21.54
112 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
113 INT56769 Gene_expression of Ntrk1 36 0.77 15.79 20.75
114 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66
115 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
116 INT12951 Negative_regulation of Cat 126 0.57 64.39 20.61
117 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61
118 INT51474 Binding of Il6 55 0.48 44.99 20.52
119 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
120 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
121 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
122 INT101188 Gene_expression of Rela 81 0.56 23.43 19.15
123 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
124 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
125 INT9246 Positive_regulation of Cat 113 0.70 52.73 18.04
126 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86
127 INT61626 Transcription of IL6 73 0.72 42.04 17.86
128 INT62826 Negative_regulation of Gene_expression of ICAM1 75 0.58 46.39 17.72
129 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
130 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
131 INT36054 Transcription of IL1B 53 0.72 32.64 17.31
132 INT50972 Negative_regulation of Ntrk1 39 0.51 32.22 17.29
133 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92
134 INT62546 Positive_regulation of Gene_expression of Icam1 60 0.70 59.52 16.9
135 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
136 INT139830 Gene_expression of AGER 47 0.75 41.71 16.53
137 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
138 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
139 INT56447 Positive_regulation of Icam1 64 0.64 64.14 16.16
140 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12
141 INT25517 Regulation of NFKB1 41 0.61 22.28 16.09
142 INT12950 Gene_expression of Cat 85 0.75 35.94 15.76
143 INT115650 Positive_regulation of Gene_expression of Camk2a 37 0.70 17.68 15.73
144 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49
145 INT54572 Negative_regulation of Positive_regulation of NFKB1 46 0.58 21.45 15.47
146 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
147 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99
148 INT79227 Negative_regulation of Gene_expression of Icam1 45 0.59 41.65 14.97
149 INT93482 Localization of Rela 56 0.78 24.52 14.82
150 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6
151 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
152 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
153 INT25266 Positive_regulation of Localization of IL1B 38 0.69 15.89 14.35
154 INT10173 Binding of Tnf 45 0.48 35.6 14.32
155 INT39733 Localization of NFKB1 59 0.79 22.76 13.99
156 INT133156 Binding of Cd40 77 0.48 45.92 13.77
157 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
158 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68
159 INT55256 Negative_regulation of Localization of Il6 38 0.58 16.12 13.67
160 INT19191 Negative_regulation of Localization of IL1B 35 0.58 15.19 13.63
161 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62
162 INT14572 Binding of INS 205 0.48 175.43 13.38
163 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
164 INT144646 Positive_regulation of Rela 53 0.67 27.78 13.2
165 INT55168 Binding of NFKB1 55 0.48 22.94 13.15
166 INT3962 Regulation of AGT 50 0.62 20.96 13.01
167 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
168 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83
169 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76
170 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
171 INT58226 Negative_regulation of Gene_expression of Il1b 24 0.57 18.09 12.68
172 INT51028 Regulation of Il1b 28 0.60 21.15 12.47
173 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34
174 INT149985 Gene_expression of Tlr9 32 0.75 29.83 11.86
175 INT50933 Transcription of Il6 38 0.72 24.31 11.58
176 INT398 Localization of AGT 45 0.78 16.97 11.54
177 INT65713 Localization of ICAM1 42 0.81 39.55 11.49
178 INT86544 Positive_regulation of Camk2a 20 0.47 4.59 11.37
179 INT49396 Negative_regulation of Positive_regulation of Il6 29 0.59 16.39 11.31
180 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
181 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
182 INT56448 Regulation of ICAM1 52 0.60 55.1 10.96
183 INT8065 Binding of AGT 54 0.48 20.54 10.85
184 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75
185 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
186 INT22132 Positive_regulation of CAT 41 0.67 18.64 10.67
187 INT133030 Positive_regulation of Gene_expression of TLR2 53 0.65 38.15 10.65
188 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
189 INT93533 Positive_regulation of Tnfsf11 53 0.50 36.93 10.53
190 INT150540 Binding of TLR2 50 0.45 35.86 10.43
191 INT50196 Transcription of Il1b 25 0.69 19.08 10.43
192 INT130867 Gene_expression of TNFSF11 106 0.77 45.15 10.34
193 INT56450 Negative_regulation of Gene_expression of Icam1 33 0.52 27.21 10.15
194 INT79720 Positive_regulation of Cat 57 0.70 31.81 10.11
195 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
196 INT120509 Gene_expression of Cat 65 0.77 50.9 9.75
197 INT80549 Binding of ICAM1 53 0.47 42.76 9.72
198 INT58986 Gene_expression of Clu 17 0.77 8.35 9.61
199 INT48078 Regulation of Gene_expression of Il1b 15 0.62 14.78 9.53
200 INT63341 Negative_regulation of ICAM1 42 0.59 30.45 9.5
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