GO:GO:0060071

From wiki-pain
Jump to: navigation, search
Name Wnt receptor signaling pathway, planar cell polarity pathway
Categary Process
Go Slim No
Go Link GO:0060071
Unique Molecular Interactions 58
Total Molecular Interactions 71
Total Single Events 746
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for Wnt receptor signaling pathway, planar cell polarity pathway. They are ordered first by their pain relevance and then by number of times they were reported for Wnt receptor signaling pathway, planar cell polarity pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
2 INT53152 Rac1 Regulation of Scg2 1 0.03 0 0.9
3 INT53155 Rac1 Positive_regulation of Gene_expression of Calca 1 0.06 0 0.89
4 INT43662 Negative_regulation of Binding of Chrna7 and Rac1 1 0.01 0 0.73
5 INT43661 Binding of Chrna7 and Rac1 1 0.01 0 0.72
6 INT330104 Binding of Sh3rf1 and Rac1 1 0.13 2.41 0.62
7 INT330101 Binding of Map3k11 and Rac1 1 0.16 2.43 0.62
8 INT131508 Gene_expression of Rac1 Positive_regulation of Trpv1 1 0.42 0.21 0.48
9 INT131503 Gene_expression of Rac1 Positive_regulation of Ngf 1 0.38 0.21 0.48
10 INT148930 Rac1 Regulation of Chrna7 1 0.13 0.6 0.44
11 INT131506 Rac1 Regulation of Positive_regulation of Mapk14 1 0.19 0.39 0.42
12 INT131505 Rac1 Regulation of Gene_expression of Trpv1 1 0.55 0.39 0.42
13 INT275156 Agt Positive_regulation of Rac1 1 0.03 2.89 0.4
14 INT330105 Rac1 Positive_regulation of Mapk8 1 0.15 1.47 0.34
15 INT330103 Rac1 Positive_regulation of Positive_regulation of Mapk8 1 0.14 1.24 0.32
16 INT330109 Binding of Racgap1 and Rac1 1 0.03 1.22 0.32
17 INT162599 Wnt5a Regulation of Gene_expression of IL4I1 1 0.00 0.1 0.28
18 INT143973 Rac1 Positive_regulation of Vti1b 1 0.00 0.16 0.2
19 INT287884 WNT5A Positive_regulation of THEMIS 1 0.00 0.08 0.13
20 INT233510 Wnt5a Positive_regulation of Gene_expression of Il12a 1 0.03 0.33 0.1
21 INT275157 Binding of Stat3 and Rac1 1 0.05 0.71 0.1
22 INT275158 Rac1 Positive_regulation of Stat3 1 0.07 0.72 0.1
23 INT211960 Wnt5a Positive_regulation of Car2 1 0.13 0.38 0.08
24 INT287879 Binding of WNT5A and FZD5 1 0.06 1.16 0.08
25 INT171709 Rac1 Negative_regulation of Localization of Chrna7 1 0.04 0.75 0.08
26 INT302632 Rac1 Positive_regulation of Gene_expression of Rhog 1 0.37 0.21 0.05
27 INT288829 Binding of Rhoa and Rac1 2 0.21 1.88 0
28 INT302640 Rac1 Regulation of Gene_expression of VEGFA 1 0.03 0 0
29 INT335884 Akt1 Regulation of Positive_regulation of Wnt5a 1 0.03 0.15 0
30 INT302641 Rac1 Regulation of TIE1 1 0.25 0.47 0
31 INT287885 Binding of DVL1 and AXIN1 1 0.02 0 0
32 INT254847 Rac1 Positive_regulation of Fbrs 1 0.09 0.81 0
33 INT228112 Gene_expression of Chrm2 Positive_regulation of Positive_regulation of Rac1 1 0.14 0.26 0
34 INT288826 Binding of Rac1 and Vav1 1 0.25 0.68 0
35 INT334474 PGGT1B Regulation of Localization of Rac1 1 0.03 0.47 0
36 INT302634 Rac1 Regulation of Gene_expression of Kdr 1 0.36 0 0
37 INT335883 Binding of Lrp6 and Wnt5a 1 0.27 0.08 0
38 INT302633 Rac1 Regulation of Cdc42ep2 1 0.01 0 0
39 INT334468 Rhoa Regulation of Localization of Rac1 1 0.25 0.18 0
40 INT254853 Rhoa Positive_regulation of Rac1 1 0.10 0.81 0
41 INT257340 Binding of Cyba and Rac1 1 0.09 0.29 0
42 INT254850 Setd1a Negative_regulation of Rac1 1 0.00 0 0
43 INT266703 Binding of RYR1 and DIXDC1 1 0.26 0.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for Wnt receptor signaling pathway, planar cell polarity pathway. They are ordered first by their pain relevance and then by number of times they were reported in Wnt receptor signaling pathway, planar cell polarity pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT19396 Regulation of Rac1 66 0.53 37.41 30.01
2 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33
3 INT23212 Positive_regulation of Rac1 46 0.55 32.85 15.1
4 INT27627 Binding of Rac1 41 0.41 22.88 13.68
5 INT50055 Negative_regulation of Rac1 36 0.50 19.74 8.98
6 INT106422 Negative_regulation of Gene_expression of Rac1 4 0.43 3.97 3.41
7 INT58475 Localization of Rac1 12 0.75 5.94 3.2
8 INT65928 Positive_regulation of Gene_expression of Rac1 12 0.42 3.34 2.33
9 INT117980 Regulation of Rac1 10 0.45 3.72 1.88
10 INT16013 Gene_expression of Rac1 52 0.75 23.79 1.21
11 INT98062 Regulation of Gene_expression of Rac1 4 0.39 1.41 1.21
12 INT150074 Gene_expression of WNT5A 8 0.75 6.3 1.17
13 INT98061 Negative_regulation of Binding of Rac1 3 0.43 2.28 1.13
14 INT67174 Negative_regulation of Rac1 22 0.56 10.72 0.99
15 INT81211 Transcription of Rac1 4 0.54 1.05 0.89
16 INT330097 Positive_regulation of Positive_regulation of Rac1 1 0.37 2.47 0.86
17 INT287954 Gene_expression of DVL1 8 0.24 2.48 0.83
18 INT264629 Localization of Rac1 8 0.72 5.7 0.79
19 INT115596 Regulation of Regulation of Rac1 1 0.36 0.29 0.7
20 INT150075 Positive_regulation of Gene_expression of WNT5A 2 0.67 2.53 0.59
21 INT228103 Positive_regulation of Rac1 25 0.67 18.92 0.57
22 INT16012 Binding of Rac1 17 0.37 6.9 0.53
23 INT81212 Negative_regulation of Transcription of Rac1 1 0.01 0 0.46
24 INT87847 Regulation of Positive_regulation of Rac1 2 0.36 1.49 0.43
25 INT124986 Positive_regulation of Localization of Rac1 3 0.50 1.22 0.33
26 INT112551 Protein_catabolism of Rac1 2 0.66 0.29 0.3
27 INT287931 Positive_regulation of Gene_expression of DVL1 2 0.09 0.08 0.29
28 INT116729 Regulation of Localization of Rac1 1 0.01 0.07 0.29
29 INT99682 Phosphorylation of Rac1 1 0.54 0.72 0.28
30 INT162873 Negative_regulation of Negative_regulation of Rac1 1 0.34 0.35 0.26
31 INT330090 Regulation of Negative_regulation of Rac1 1 0.36 0.53 0.25
32 INT330093 Negative_regulation of Positive_regulation of Rac1 1 0.34 0.88 0.23
33 INT289128 Negative_regulation of Gene_expression of DVL1 1 0.07 0.31 0.17
34 INT289117 Negative_regulation of DVL1 1 0.07 0.31 0.17
35 INT168055 Regulation of Transcription of Rac1 1 0.36 0.34 0.16
36 INT133599 Positive_regulation of Binding of Rac1 2 0.40 0.4 0.15
37 INT330085 Regulation of Binding of Rac1 1 0.36 0.28 0.15
38 INT287922 Phosphorylation of DVL1 4 0.20 1.21 0.12
39 INT162574 Gene_expression of Wnt5a 7 0.47 0.92 0.1
40 INT282594 Localization of WNT5A 2 0.18 0.89 0.1
41 INT233483 Regulation of Gene_expression of Wnt5a 1 0.19 0.33 0.1
42 INT302613 Positive_regulation of Gene_expression of Rac1 14 0.67 3.7 0.08
43 INT162576 Positive_regulation of Wnt5a 3 0.48 0.71 0.08
44 INT334443 Positive_regulation of Positive_regulation of Rac1 1 0.33 1.1 0.08
45 INT290078 Regulation of WNT5A 1 0.07 2.3 0.07
46 INT287947 Binding of DVL1 3 0.10 0.95 0.06
47 INT302624 Negative_regulation of Gene_expression of Rac1 1 0.56 3.67 0.06
48 INT323949 Negative_regulation of Positive_regulation of Rac1 1 0.23 0.53 0.05
49 INT334445 Regulation of Positive_regulation of Rac1 1 0.40 1.73 0.04
50 INT287920 Positive_regulation of DVL1 3 0.49 1.29 0.03
51 INT302611 Regulation of Gene_expression of Rac1 1 0.43 4.5 0.03
52 INT302615 Transcription of Rac1 5 0.66 1.1 0
53 INT287937 Positive_regulation of Positive_regulation of DVL1 2 0.12 0.52 0
54 INT334450 Regulation of Localization of Rac1 1 0.30 0.65 0
55 INT228095 Phosphorylation of Rac1 1 0.34 0.21 0
56 INT302609 Positive_regulation of Transcription of Rac1 1 0.48 0.27 0
57 INT300638 Transcription of DVL1 1 0.33 1.11 0
58 INT302631 Regulation of Transcription of Rac1 1 0.43 0.47 0
59 INT335880 Regulation of Wnt5a 1 0.32 0.07 0
60 INT302621 Regulation of Negative_regulation of Rac1 1 0.43 0 0
61 INT302627 Negative_regulation of Localization of Rac1 1 0.41 0.28 0
62 INT302620 Negative_regulation of Transcription of Rac1 1 0.41 0 0
63 INT334438 Positive_regulation of Localization of Rac1 1 0.33 2.37 0
64 INT230271 Transcription of DIXDC1 1 0.20 1.24 0
65 INT254786 Positive_regulation of Negative_regulation of Rac1 1 0.26 0.95 0
66 INT162572 Positive_regulation of Gene_expression of Wnt5a 1 0.02 0.3 0
67 INT302614 Positive_regulation of Binding of Rac1 1 0.48 0.31 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox