GOS:GTPase activity

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This page displays the top molecular interactions and top single events that were mentioned in the literature for GTPase activity. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for GTPase activity. They are ordered first by their pain relevance and then by number of times they were reported for GTPase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Genes linked to GTPase activity Documents TM Confidence Disease Relevance Pain Relevance
1 INT269444 Binding of RAB5A and HHIP 1 1 0.04 0 5.79
2 INT103724 Oprd1 Positive_regulation of Gtpbp4 2 3 0.30 0.91 4.18
3 INT264929 Binding of Cnr1 and Gnaz 2 1 0.18 1.71 2.89
4 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 1 0.06 0.5 2.6
5 INT96465 Pnoc Positive_regulation of GEM 1 1 0.01 0.74 2.39
6 INT133946 Binding of DNM2 and OPRK1 2 1 0.11 0 2.1
7 INT13940 DNM2 Regulation of Localization of CGA 2 1 0.11 0 1.86
8 INT134363 Prkcg Regulation of ADCY2 1 1 0.00 0.14 1.7
9 INT80199 Ngf Regulation of Transcription of Rab38 2 1 0.01 1.48 1.68
10 INT103725 Negative_regulation of Oprd1 Positive_regulation of Gtpbp4 2 1 0.17 0.38 1.65
11 INT103726 Regulation of Oprd1 Positive_regulation of Gtpbp4 2 1 0.10 0.38 1.64
12 INT317184 BMS1 Regulation of Gene_expression of NAV1 1 1 0.03 1.94 1.62
13 INT247281 GLC1N Negative_regulation of HRAS 1 1 0.02 1.98 1.62
14 INT351366 LPA Positive_regulation of Rab38 2 1 0.00 0.95 1.53
15 INT240057 Binding of RHOB and NME8 1 1 0.41 4.11 1.5
16 INT21425 Binding of Pomc and Gtpbp4 2 1 0.01 0.1 1.45
17 INT133933 Binding of DNM2 and TP53INP2 2 1 0.00 0 1.38
18 INT122659 Binding of CACNA1A and SAR1B 1 1 0.06 1.38 1.35
19 INT115985 Cpe Positive_regulation of Binding of Gnas and 3 1 0.00 0.17 1.28
20 INT121464 Negative_regulation of Oprm1 Positive_regulation of Dnm2 1 1 0.34 0 1.26
21 INT121465 Binding of Dnm2 and Oprm1 1 1 0.23 0 1.24
22 INT124874 Gnat3 Positive_regulation of Localization of Calca 2 2 0.08 0.75 1.2
23 INT21424 Binding of Penk and Gtpbp4 2 1 0.02 0.16 1.2
24 INT65203 OPRL1 Negative_regulation of ADCY1 1 1 0.19 0 1.19
25 INT116730 Rac1 Regulation of Localization of Calca 2 1 0.13 1.32 1.19
26 INT49955 OPRM1 Positive_regulation of ADCY1 1 1 0.21 0.31 1.19
27 INT264930 Gnaz Positive_regulation of Negative_regulation of Cnr1 2 1 0.20 0 1.14
28 INT65204 PNOC Negative_regulation of ADCY1 1 1 0.07 0 1.14
29 INT117504 OPA1 Positive_regulation of CPP 1 1 0.09 1.09 1.13
30 INT130627 Gnas Regulation of Prkaca 3 1 0.00 0 1.13
31 INT264931 Binding of Gnaz and Hrh1 2 1 0.01 0.83 1.12
32 INT64259 Binding of Gtpbp4 and Ptprg 2 1 0.06 0 1.1
33 INT269443 Positive_regulation of Binding of RAB5A and HHIP 1 1 0.04 0 1.06
34 INT18828 DNM2 Positive_regulation of Localization of LTB4R 2 1 0.01 0.07 1.06
35 INT118859 GNA14 Positive_regulation of STAT3 1 1 0.01 0.38 1.03
36 INT224856 Binding of Bdnf and Eef2 1 1 0.14 0 1.02
37 INT157142 OPA1 Positive_regulation of Gene_expression of Camk2a 1 1 0.02 0.3 1.02
38 INT144661 Dnm1 Negative_regulation of Binding of Hbegf and 1 1 0.24 0 1.01
39 INT53052 ANTXRL Negative_regulation of Negative_regulation of ADCY1 1 1 0.01 0.66 0.99
40 INT61637 Binding of P2ry2 and Gtpbp4 2 1 0.02 0.1 0.99
41 INT166790 HRAS Negative_regulation of Gene_expression of PTGER1 1 1 0.01 1.46 0.95
42 INT73466 PTPLA Positive_regulation of Transcription of Hras1 1 1 0.21 0.98 0.95
43 INT264926 Binding of Gnaz and Pag1 2 1 0.08 0.19 0.94
44 INT153685 Binding of Bcl2l11 and Gtpbp4 2 1 0.08 0.76 0.93
45 INT54202 Gnai1 Negative_regulation of Binding of Pag1 and Agp2 2 1 0.01 0.18 0.91
46 INT52114 Oprd1 Regulation of ADCY1 1 2 0.05 0.46 0.9
47 INT54200 Gnai1 Negative_regulation of Pag1 2 1 0.05 0.18 0.9
48 INT54197 Binding of Gnai1 and Pag1 2 1 0.04 0.18 0.9
49 INT53152 Rac1 Regulation of Scg2 2 1 0.03 0 0.9
50 INT121702 HRAS Negative_regulation of Positive_regulation of MMP1 1 1 0.06 0.2 0.9
51 INT54187 Gnai1 Negative_regulation of Binding of Oprd1 and Pag1 2 1 0.00 0.18 0.9
52 INT121701 HRAS Negative_regulation of MMP1 1 1 0.06 0.2 0.89
53 INT121704 HRAS Negative_regulation of MMP3 1 1 0.06 0.19 0.89
54 INT53155 Rac1 Positive_regulation of Gene_expression of Calca 2 1 0.06 0 0.89
55 INT301079 Binding of GNAT1 and INPP5E 2 1 0.00 0.59 0.89
56 INT121699 HRAS Negative_regulation of Gene_expression of MMP1 1 1 0.06 0.19 0.88
57 INT52390 OPRD1 Regulation of ADCY1 1 1 0.09 0.13 0.86
58 INT114324 RAF1 Positive_regulation of Phosphorylation of ADCY6 1 1 0.02 0.05 0.85
59 INT124878 Gnat3 Negative_regulation of Gene_expression of FOS 2 1 0.09 0.16 0.85
60 INT114323 Binding of ADCY6 and RAF1 1 1 0.02 0.05 0.85
61 INT80877 Negative_regulation of PCDHB17 Negative_regulation of ADCY1 1 1 0.01 0.08 0.84
62 INT80878 PCDHB17 Negative_regulation of ADCY1 1 1 0.01 0.08 0.84
63 INT74383 Sst Positive_regulation of GEM 1 1 0.01 0.09 0.82
64 INT269455 Binding of RAB5A and GOPC 1 1 0.08 0 0.82
65 INT74382 Negative_regulation of Sst Positive_regulation of GEM 1 1 0.00 0.09 0.82
66 INT124877 Gnat3 Negative_regulation of FOS 2 1 0.09 0.15 0.82
67 INT124876 Gnat3 Negative_regulation of Positive_regulation of FOS 2 1 0.09 0.15 0.82
68 INT74384 Regulation of Sst Positive_regulation of GEM 1 1 0.00 0.09 0.82
69 INT80200 Negative_regulation of Ngf Negative_regulation of Gene_expression of Rab38 2 1 0.01 0.68 0.8
70 INT128180 Gna12 Regulation of Regulation of RHOA 4 1 0.00 0 0.78
71 INT142454 Npff Positive_regulation of Gtpbp4 2 1 0.56 0 0.78
72 INT142455 Binding of Npff and Gtpbp4 2 1 0.40 0 0.78
73 INT81976 Binding of GNA15 and OPRL1 1 1 0.02 0 0.77
74 INT118854 GNA14 Positive_regulation of Positive_regulation of STAT3 1 1 0.02 0.31 0.76
75 INT133935 DNM2 Positive_regulation of OPRK1 2 1 0.11 0 0.76
76 INT65593 CALCA Negative_regulation of Positive_regulation of ADCY1 1 1 0.23 0.07 0.76
77 INT162164 ARF6 Regulation of Positive_regulation of PLD2 1 1 0.60 0 0.74
78 INT43662 Negative_regulation of Binding of Chrna7 and Rac1 2 1 0.01 0 0.73
79 INT148909 Binding of GNA13 and TP53INP2 1 1 0.06 0.31 0.73
80 INT133943 Binding of DNM2 and OPRL1 2 1 0.00 0 0.73
81 INT43663 Binding of Chrna7 and Rac2 2 1 0.01 0 0.72
82 INT43661 Binding of Chrna7 and Rac1 2 1 0.01 0 0.72
83 INT162162 ARF6 Regulation of OPRM1 1 1 0.19 0 0.71
84 INT262574 Gnaq Positive_regulation of Prkca 2 1 0.00 0.57 0.71
85 INT123869 Binding of GNAS and OPRK1 2 1 0.00 0.37 0.7
86 INT43647 Binding of Eef1a1 and Man2a2 1 1 0.16 0.23 0.7
87 INT133936 Binding of DNM2 and YY1 2 1 0.29 0 0.69
88 INT74599 YY1 Negative_regulation of ADCY1 1 2 0.36 0.31 0.67
89 INT121966 HRAS Positive_regulation of RAC1 2 1 0.75 0.41 0.67
90 INT113931 Mors1 Positive_regulation of Gtpbp4 2 1 0.02 0 0.67
91 INT264927 Cnr1 Regulation of Gnaz 2 1 0.23 0.05 0.66
92 INT118824 OPA1 Positive_regulation of Gene_expression of Nos1 1 2 0.03 0.24 0.65
93 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 1 0.44 0.06 0.65
94 INT184193 HRAS Negative_regulation of Gene_expression of IL1B 1 1 0.00 1.12 0.65
95 INT62849 TUBE1 Positive_regulation of Rmp1 1 1 0.02 0 0.65
96 INT34211 DNM2 Regulation of Localization of Crh 2 1 0.01 0.09 0.63
97 INT334594 Binding of GNAI1 and MRGPRD 3 1 0.01 0.19 0.63
98 INT36511 Binding of Htr2a and Eef1a1 1 1 0.22 0 0.62
99 INT330104 Binding of Sh3rf1 and Rac1 2 1 0.13 2.41 0.62
100 INT330101 Binding of Map3k11 and Rac1 2 1 0.16 2.43 0.62
101 INT247285 GLC1N Positive_regulation of Gene_expression of HRAS 1 1 0.02 1.3 0.61
102 INT142993 Serpinc1 Positive_regulation of Phosphorylation of RHOA 1 1 0.05 0.05 0.59
103 INT161387 Binding of PNOC and GTPBP4 1 1 0.03 1.05 0.59
104 INT41250 Binding of Adra2a and Eef1a1 1 1 0.06 0.4 0.56
105 INT210830 OPRM1 Negative_regulation of ADCY1 1 1 0.00 0.06 0.55
106 INT59635 Binding of Adarb1 and Gnaz 2 1 0.01 0 0.55
107 INT32908 Binding of ADCY1 and Drd2 1 1 0.00 0 0.54
108 INT64744 OR5D2P Negative_regulation of ADCY1 1 1 0.00 0 0.54
109 INT164971 Binding of Rgs7 and Gnai2 1 1 0.01 0 0.54
110 INT269449 Positive_regulation of Binding of RAB5A and GOPC 1 1 0.11 0 0.53
111 INT164970 Binding of Rgs8 and Gnai2 1 1 0.01 0 0.53
112 INT97949 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of CDC42 2 1 0.06 0.72 0.51
113 INT77218 Binding of NFKBIL1 and NKIRAS2 1 1 0.00 0.27 0.51
114 INT182813 EEF1A2 Negative_regulation of ITGAL 1 1 0.10 1.53 0.51
115 INT33415 KNG1 Positive_regulation of GBP1 1 1 0.02 0.43 0.51
116 INT93265 Binding of ADCY1 and OPRL1 1 1 0.13 0.17 0.51
117 INT97953 ST3GAL3 Positive_regulation of CDC42 2 1 0.09 0.7 0.5
118 INT81004 Htr1a Positive_regulation of Gtpbp4 2 1 0.20 0 0.5
119 INT243998 Binding of Prkaca and Dnm1 1 1 0.11 0.24 0.49
120 INT243999 Positive_regulation of Binding of Prkaca and Dnm1 1 1 0.14 0.24 0.49
121 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 1 0.04 0.24 0.49
122 INT243997 Binding of Tfap2a and Dnm1 1 1 0.03 0.24 0.49
123 INT131508 Gene_expression of Rac1 Positive_regulation of Trpv1 2 1 0.42 0.21 0.48
124 INT131503 Gene_expression of Rac1 Positive_regulation of Ngf 2 1 0.38 0.21 0.48
125 INT155881 Binding of CDX2 and KRAS 1 1 0.40 1.51 0.47
126 INT89647 OPRM1 Regulation of ADCY1 1 1 0.09 0.09 0.47
127 INT153658 PRKCA Negative_regulation of GEM 1 1 0.01 0.22 0.46
128 INT95564 Positive_regulation of HRAS Positive_regulation of IL12A 1 1 0.03 0.7 0.45
129 INT95562 HRAS Positive_regulation of IL12A 1 1 0.03 0.7 0.45
130 INT95563 HRAS Positive_regulation of TNF 1 1 0.03 0.7 0.45
131 INT258584 ADORA3 Negative_regulation of ADCY1 1 1 0.02 0 0.44
132 INT111275 BRI3P1 Positive_regulation of Negative_regulation of ADCY1 1 1 0.06 0 0.44
133 INT148930 Rac1 Regulation of Chrna7 2 1 0.13 0.6 0.44
134 INT89649 INSRR Regulation of ADCY1 1 1 0.00 0.07 0.44
135 INT111274 C2 Positive_regulation of Negative_regulation of ADCY1 1 1 0.14 0 0.44
136 INT72016 Positive_regulation of Binding of Gnai2 and Ptprg 1 1 0.02 0 0.44
137 INT73832 Pld1 Positive_regulation of ADCY1 1 1 0.00 0.16 0.44
138 INT169466 TGFB3 Positive_regulation of HRAS 1 1 0.03 0.89 0.43
139 INT56578 Eef1a1 Positive_regulation of Localization of Gnrh1 1 1 0.16 0 0.43
140 INT124088 Rab38 Negative_regulation of Mapk14 2 1 0.00 0.89 0.42
141 INT251430 Gnat3 Positive_regulation of Gucy1b2 2 1 0.04 0.48 0.42
142 INT346218 Positive_regulation of Kras Positive_regulation of Phosphorylation of Mdk 2 1 0.01 0.71 0.42
143 INT247287 Gene_expression of GLC1N Regulation of Gene_expression of HRAS 1 1 0.02 0.56 0.42
144 INT40208 Binding of Eef1a1 and Hils1 1 1 0.01 0.22 0.42
145 INT131506 Rac1 Regulation of Positive_regulation of Mapk14 2 1 0.19 0.39 0.42
146 INT269448 HHIP Positive_regulation of Binding of RAB5A and 1 1 0.04 0 0.42
147 INT131505 Rac1 Regulation of Gene_expression of Trpv1 2 1 0.55 0.39 0.42
148 INT146274 Binding of Rasd1 and Nos1ap 1 1 0.33 0.18 0.41
149 INT134114 Gnai2 Positive_regulation of Oprd1 Regulation of ADCY1 2 1 0.00 0.47 0.41
150 INT114516 Eef1a1 Positive_regulation of Transcription of co 1 1 0.00 0 0.41
151 INT146273 Binding of Nos1 and Rasd1 1 1 0.34 0.18 0.41
152 INT68526 Binding of ADCY1 and DIO2 1 1 0.01 0.07 0.41
153 INT207110 Adam3 Regulation of Gene_expression of Eef1a1 1 1 0.01 1 0.41
154 INT80233 Positive_regulation of OPRM1 Positive_regulation of GNAI1 3 1 0.23 0 0.41
155 INT72018 Binding of Gnai2 and Ptprg 1 1 0.01 0 0.41
156 INT68527 Binding of ADCY1 and OPRD1 1 1 0.06 0.07 0.41
157 INT105170 OPRD1 Positive_regulation of Phosphorylation of ADCY1 1 1 0.08 0 0.41
158 INT80232 OPRM1 Positive_regulation of GNAI1 3 1 0.23 0 0.41
159 INT11425 OR2A12 Positive_regulation of Negative_regulation of ADCY1 1 1 0.01 0 0.4
160 INT351237 HRAS Regulation of CBL 1 1 0.00 0.48 0.4
161 INT105169 RAF1 Regulation of Positive_regulation of ADCY1 1 1 0.12 0 0.4
162 INT124799 PRKCA Positive_regulation of Localization of ADCY6 1 1 0.19 0 0.4
163 INT162289 Binding of TUBA1A and Phospho2 1 1 0.31 1.26 0.4
164 INT56876 Regulation of Binding of Cd36 and Gtpbp4 2 1 0.00 0 0.4
165 INT56875 Binding of Cd36 and Gtpbp4 2 1 0.00 0 0.4
166 INT275156 Agt Positive_regulation of Rac1 2 1 0.03 2.89 0.4
167 INT162288 Regulation of Binding of TUBA1A and Phospho2 1 1 0.24 1.28 0.4
168 INT166788 HRAS Negative_regulation of Phosphorylation of NFKB1 1 1 0.08 0.5 0.39
169 INT269456 RAB5A Regulation of Binding of HHIP and 1 1 0.04 0 0.38
170 INT180442 Acot1 Positive_regulation of Rhoa 2 1 0.08 1.03 0.38
171 INT104992 Ptger3 Regulation of Rab38 2 1 0.02 0.79 0.38
172 INT166792 Binding of CD44 and HRAS 1 3 0.12 1.49 0.37
173 INT300610 Rorb Regulation of Dnm2 2 1 0.01 0.27 0.37
174 INT300608 Arc Regulation of Dnm2 2 1 0.15 0.27 0.37
175 INT173356 Gnaq Positive_regulation of CDK20 2 1 0.06 0 0.37
176 INT26552 Gene_expression of Mras Positive_regulation of Gene_expression of KNG1 1 1 0.03 0.07 0.36
177 INT257741 HRAS Negative_regulation of PTEN 1 1 0.15 1.06 0.35
178 INT251426 Gnat3 Negative_regulation of Aldh2 2 1 0.22 0 0.35
179 INT257737 Positive_regulation of HRAS Negative_regulation of PTEN 1 1 0.17 1.07 0.35
180 INT330105 Rac1 Positive_regulation of Mapk8 2 1 0.15 1.47 0.34
181 INT134080 OPA1 Negative_regulation of Phosphorylation of Gnb2l1 1 1 0.03 0.22 0.34
182 INT88252 Binding of RAP1A and Krit1 1 1 0.36 2.25 0.33
183 INT20468 Ran Negative_regulation of Localization of Prl 1 1 0.30 0 0.33
184 INT109282 Gdi2 Negative_regulation of Gtpbp4 2 1 0.01 0.13 0.32
185 INT330103 Rac1 Positive_regulation of Positive_regulation of Mapk8 2 1 0.14 1.24 0.32
186 INT241776 Binding of AVP and Positive_regulation of ADCY1 1 1 0.06 0.54 0.32
187 INT295722 PTGER2 Positive_regulation of RAC1 1 1 0.02 2.14 0.32
188 INT330109 Binding of Racgap1 and Rac1 2 1 0.03 1.22 0.32
189 INT161435 OPA1 Positive_regulation of Gene_expression of Tnc 1 1 0.02 0.21 0.32
190 INT295725 PTGER2 Positive_regulation of RAC2 1 1 0.05 1.92 0.32
191 INT285567 Binding of IL1B and Cdc42 3 1 0.03 0.77 0.31
192 INT152061 Binding of SEPT9 and CD177 1 1 0.00 1.76 0.31
193 INT303105 CAMK4 Positive_regulation of Hras1 1 1 0.04 0.16 0.31
194 INT169612 OGFR Regulation of RAN 1 1 0.23 0.14 0.3
195 INT166789 HRAS Regulation of Positive_regulation of NFKB1 1 1 0.05 0.31 0.3
196 INT260438 Binding of Cd4 and Mx1 1 1 0.00 1.52 0.29
197 INT265467 HRAS Negative_regulation of Gene_expression of PTGS2 1 1 0.01 0.84 0.29
198 INT260434 Binding of Cd8a and Mx1 1 1 0.00 1.52 0.29
199 INT339001 GSX1 Positive_regulation of ADCY1 1 1 0.01 0 0.29
200 INT141438 Gnai2 Positive_regulation of Localization of ADCY1 2 1 0.01 0.43 0.29

Single Events

The table below shows the top 100 pain related interactions that have been reported for GTPase activity. They are ordered first by their pain relevance and then by number of times they were reported in GTPase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6490 Negative_regulation of ADCY1 145 0.58 26.25 70.96
2 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9
3 INT9298 Positive_regulation of Gtpbp4 64 0.69 12.29 41.97
4 INT19396 Regulation of Rac1 66 0.53 37.41 30.01
5 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33
6 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78
7 INT12617 Regulation of ADCY1 41 0.61 7.38 15.94
8 INT7531 Positive_regulation of Eef1a1 29 0.62 8.16 15.41
9 INT23212 Positive_regulation of Rac1 46 0.55 32.85 15.1
10 INT49089 Gene_expression of Rab38 22 0.45 6.79 13.76
11 INT27627 Binding of Rac1 41 0.41 22.88 13.68
12 INT21421 Regulation of Gtpbp4 15 0.30 2.7 13.49
13 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21
14 INT146197 Positive_regulation of Rhoa 60 0.68 34.12 12.02
15 INT49087 Positive_regulation of Rab38 20 0.00 8.01 12
16 INT11429 Gene_expression of ADCY1 26 0.74 5.89 11.93
17 INT16659 Gene_expression of Eef1a1 34 0.64 6.1 11.85
18 INT40486 Positive_regulation of Positive_regulation of ADCY1 20 0.48 4.29 11.33
19 INT204112 Gene_expression of GEM 43 0.75 38.74 11.23
20 INT9586 Gene_expression of Eef1a2 29 0.65 6.79 11.12
21 INT91357 Regulation of Dnm2 5 0.61 0 11.06
22 INT67915 Negative_regulation of Gtpbp4 18 0.33 6.31 10.17
23 INT12620 Negative_regulation of Negative_regulation of ADCY1 16 0.44 2.98 10.1
24 INT62919 Regulation of Gnas 22 0.43 5.61 9.55
25 INT106595 Negative_regulation of Dnm2 10 0.58 0.15 9.29
26 INT50055 Negative_regulation of Rac1 36 0.50 19.74 8.98
27 INT9968 Negative_regulation of Rab38 15 0.00 10.45 8.64
28 INT1682 Negative_regulation of Rem1 28 0.37 7.38 8.4
29 INT54681 Negative_regulation of Positive_regulation of ADCY1 16 0.38 2.7 8.14
30 INT6384 Regulation of Eef1a1 21 0.61 2.95 7.97
31 INT68434 Gene_expression of Gtpbp4 15 0.54 5.5 7.91
32 INT264910 Positive_regulation of Gnaz 1 0.30 0 7.82
33 INT14207 Gene_expression of DNM2 20 0.67 5.76 7.64
34 INT6341 Binding of Gtpbp4 11 0.44 1.54 7.3
35 INT77756 Positive_regulation of GTPBP4 16 0.11 2.6 7.29
36 INT106599 Positive_regulation of Dnm2 8 0.69 0.28 7.01
37 INT18578 Binding of Eef1a1 20 0.48 2.53 6.95
38 INT25467 Regulation of Rab38 19 0.00 8.68 6.73
39 INT234813 Gene_expression of RAB5A 58 0.66 3.67 6.48
40 INT103723 Regulation of Positive_regulation of Gtpbp4 5 0.22 1.56 6.35
41 INT11258 Gene_expression of Gnas 58 0.58 21.6 6.33
42 INT67635 Negative_regulation of Gnas 29 0.04 11.4 6.32
43 INT20899 Negative_regulation of GNAI1 12 0.57 4.24 6.07
44 INT34742 Gene_expression of Gnat3 44 0.67 6.83 5.65
45 INT69350 Gene_expression of RAC1 23 0.77 12.16 5.54
46 INT72000 Gene_expression of Gnaq 17 0.75 3.12 5.48
47 INT15367 Gene_expression of OPA1 35 0.67 24.9 5.45
48 INT44997 Positive_regulation of Eef1a2 16 0.40 8.84 5.37
49 INT80881 Phosphorylation of ADCY1 7 0.69 1.22 5.29
50 INT18577 Negative_regulation of Eef1a1 20 0.39 3.57 5.24
51 INT33854 Localization of OPA1 19 0.65 10.55 5.04
52 INT34870 Positive_regulation of OPA1 18 0.59 10.66 5
53 INT62920 Regulation of Gnai1 3 0.52 0.08 4.78
54 INT255981 Localization of RAB5A 3 0.68 0.88 4.76
55 INT269476 Binding of RAB5A 1 0.41 0 4.76
56 INT128178 Positive_regulation of RHOA 59 0.68 9.3 4.7
57 INT17391 Gene_expression of GNAI1 11 0.75 5.26 4.7
58 INT17393 Positive_regulation of GNAI1 17 0.49 2.42 4.66
59 INT88909 Positive_regulation of Gene_expression of Dnm1 6 0.70 3.43 4.59
60 INT26546 Positive_regulation of Gene_expression of Hras1 35 0.70 16.59 4.54
61 INT106596 Transcription of Dnm2 4 0.69 0 4.5
62 INT14574 Positive_regulation of Negative_regulation of ADCY1 9 0.66 2.45 4.39
63 INT96464 Positive_regulation of GEM 7 0.45 5.48 4.37
64 INT98357 Binding of Gnas 11 0.41 1.87 4.35
65 INT63113 Positive_regulation of HRAS 30 0.67 22.85 4.28
66 INT20981 Binding of HRAS 42 0.48 24.49 4.23
67 INT34624 Negative_regulation of REM1 22 0.38 9.25 4.22
68 INT34829 Positive_regulation of Gnat3 27 0.46 5.24 4.14
69 INT74203 Positive_regulation of Positive_regulation of Gtpbp4 6 0.50 0.33 4.13
70 INT206601 Gene_expression of Gnb1 1 0.73 3.6 4.1
71 INT32933 Gene_expression of GNAS 57 0.32 10.58 4.03
72 INT109861 Gene_expression of Rhoa 11 0.78 5.67 4.02
73 INT80175 Positive_regulation of Gene_expression of HRAS 24 0.67 14.69 3.97
74 INT169475 Localization of HRAS 14 0.73 9.02 3.9
75 INT112928 Localization of Dnm2 3 0.74 0 3.81
76 INT78619 Positive_regulation of RAC1 27 0.65 10.43 3.75
77 INT12841 Gene_expression of Gnao1 6 0.60 1.34 3.7
78 INT88906 Gene_expression of Dnm1 5 0.78 10.48 3.7
79 INT87408 Negative_regulation of ADCY2 3 0.01 0.1 3.68
80 INT25136 Localization of Gnat3 23 0.75 5.01 3.65
81 INT126685 Gene_expression of Rem1 30 0.65 11.21 3.61
82 INT53706 Positive_regulation of Kras 13 0.67 9.26 3.57
83 INT24883 Regulation of OPA1 14 0.45 9.73 3.44
84 INT87281 Localization of ADCY1 7 0.64 1.84 3.42
85 INT121967 Regulation of RAC1 9 0.45 6.14 3.41
86 INT106422 Negative_regulation of Gene_expression of Rac1 4 0.43 3.97 3.41
87 INT12639 Gene_expression of Gnai2 6 0.24 0.35 3.4
88 INT117117 Positive_regulation of REM1 12 0.40 10.1 3.33
89 INT25466 Binding of Rab38 6 0.00 2.23 3.28
90 INT139010 Regulation of Gfm1 16 0.32 5.02 3.27
91 INT137679 Localization of Gfm1 18 0.08 9.58 3.24
92 INT146194 Negative_regulation of Rhoa 21 0.42 11.05 3.22
93 INT19393 Gene_expression of Gfm1 31 0.51 18.9 3.2
94 INT58475 Localization of Rac1 12 0.75 5.94 3.2
95 INT28166 Positive_regulation of Rem1 8 0.40 7.96 3.19
96 INT317186 Regulation of BMS1 1 0.04 3.9 3.17
97 INT13179 Regulation of Positive_regulation of ADCY1 5 0.34 0.89 3.08
98 INT128179 Gene_expression of RHOA 7 0.64 2.48 3.01
99 INT301081 Positive_regulation of GNAT1 1 0.12 4.16 3
100 INT59309 Negative_regulation of Gene_expression of ADCY1 3 0.42 1.04 2.98
101 INT146191 Gene_expression of Rhoa 32 0.67 17.63 2.92
102 INT5913 Binding of OPA1 12 0.41 9.33 2.92
103 INT12638 Positive_regulation of Gnai2 5 0.52 1.16 2.91
104 INT69641 Positive_regulation of ADCY2 5 0.32 0.18 2.87
105 INT3605 Negative_regulation of OPA1 14 0.38 10.88 2.84
106 INT109833 Binding of GNB3 7 0.48 8.83 2.84
107 INT30815 Binding of ADCY1 7 0.36 0.21 2.79
108 INT136784 Phosphorylation of Eef2 4 0.55 0 2.79
109 INT13943 Localization of DNM2 4 0.52 0.07 2.75
110 INT121463 Regulation of Localization of Dnm2 2 0.45 0 2.72
111 INT234825 Positive_regulation of Gene_expression of RAB5A 16 0.59 1.15 2.71
112 INT11196 Negative_regulation of Gnat3 26 0.37 3.14 2.69
113 INT264915 Positive_regulation of Localization of Gnaz 1 0.19 0 2.68
114 INT62683 Negative_regulation of HRAS 19 0.57 7.93 2.65
115 INT44998 Regulation of Eef1a2 6 0.42 2.37 2.65
116 INT80884 Positive_regulation of Phosphorylation of ADCY1 4 0.43 0.24 2.64
117 INT11426 Positive_regulation of Gene_expression of ADCY1 5 0.29 0.68 2.63
118 INT204116 Regulation of Gene_expression of GEM 8 0.29 8.66 2.6
119 INT204110 Positive_regulation of Gene_expression of GEM 11 0.67 8.85 2.57
120 INT140363 Negative_regulation of Rhoa 7 0.58 2.49 2.47
121 INT72013 Negative_regulation of Gnai2 5 0.35 0.09 2.44
122 INT44880 Gene_expression of REM1 21 0.30 5.3 2.43
123 INT111039 Gene_expression of Kras 20 0.60 15.42 2.39
124 INT128174 Positive_regulation of Gene_expression of RHOA 7 0.36 1.5 2.36
125 INT80194 Transcription of Rab38 4 0.04 1.85 2.35
126 INT139008 Positive_regulation of Gfm1 21 0.35 7.79 2.34
127 INT65928 Positive_regulation of Gene_expression of Rac1 12 0.42 3.34 2.33
128 INT124641 Localization of Igtp 1 0.34 0 2.33
129 INT146196 Localization of Rhoa 6 0.78 4.68 2.3
130 INT131850 Gene_expression of RHOC 17 0.72 29.06 2.28
131 INT71268 Positive_regulation of Gene_expression of Eef1a1 7 0.41 1.75 2.26
132 INT71266 Regulation of Gene_expression of Eef1a1 1 0.51 0 2.2
133 INT146192 Positive_regulation of Positive_regulation of Rhoa 8 0.60 8.15 2.17
134 INT95076 Gene_expression of Rab5a 2 0.75 0.58 2.15
135 INT70987 Binding of RAC1 14 0.37 12.14 2.13
136 INT16226 Negative_regulation of Rit2 10 0.59 1.42 2.1
137 INT179311 Transcription of GNAS 2 0.10 0.67 2.08
138 INT69196 Positive_regulation of Rap1a 2 0.29 1.18 2.06
139 INT108903 Negative_regulation of GNAS 7 0.57 1.58 2.04
140 INT17390 Regulation of GNAI1 5 0.04 3.58 2.03
141 INT12636 Positive_regulation of Gene_expression of Gnai2 1 0.18 0.16 2.01
142 INT65993 Localization of Gnai1 1 0.46 0.08 2
143 INT92108 Gene_expression of Tubb3 3 0.12 1.94 1.97
144 INT112880 Positive_regulation of Gnaq 17 0.49 1.97 1.95
145 INT76993 Regulation of HRAS 8 0.60 7.81 1.95
146 INT12637 Negative_regulation of Gnai2 5 0.33 1.07 1.93
147 INT68435 Regulation of Gene_expression of Gtpbp4 4 0.34 0.96 1.89
148 INT9297 Localization of Gtpbp4 4 0.17 0.88 1.89
149 INT25871 Negative_regulation of Gnaz 3 0.23 0 1.89
150 INT117980 Regulation of Rac1 10 0.45 3.72 1.88
151 INT126626 Positive_regulation of Rhoa 14 0.69 4.43 1.87
152 INT57618 Binding of GTPBP4 9 0.43 1.61 1.87
153 INT301080 Binding of GNAT1 1 0.10 2.04 1.85
154 INT146193 Negative_regulation of Positive_regulation of Rhoa 3 0.42 3 1.84
155 INT240058 Gene_expression of RHOB 2 0.55 4.29 1.84
156 INT85348 Localization of RHOA 12 0.59 4.81 1.83
157 INT17387 Gene_expression of Gnaz 3 0.50 0.4 1.81
158 INT6628 Transcription of Eef1a1 4 0.16 2.59 1.8
159 INT136782 Positive_regulation of Phosphorylation of Eef2 1 0.41 0 1.78
160 INT163157 Binding of BMS1 3 0.42 3.6 1.77
161 INT128168 Positive_regulation of Gna12 1 0.01 0 1.76
162 INT134991 Regulation of Rem1 4 0.28 3.45 1.71
163 INT25192 Positive_regulation of Gene_expression of GNAI1 5 0.49 1.08 1.7
164 INT234827 Positive_regulation of RAB5A 3 0.59 0.54 1.69
165 INT109975 Positive_regulation of Kras 14 0.45 12.72 1.68
166 INT96823 Positive_regulation of Positive_regulation of GTPBP4 3 0.05 0.41 1.67
167 INT32939 Positive_regulation of Positive_regulation of Eef1a1 2 0.19 0 1.67
168 INT80195 Regulation of Gene_expression of Rab38 2 0.04 2.23 1.66
169 INT174656 Binding of NCF1 5 0.37 6.46 1.65
170 INT111886 Gene_expression of Dnm2 3 0.69 0.91 1.65
171 INT87289 Positive_regulation of Localization of ADCY1 3 0.43 0.36 1.65
172 INT136786 Regulation of Eef2 3 0.61 0 1.64
173 INT31616 Protein_catabolism of DNM2 5 0.75 1.61 1.63
174 INT110189 Regulation of Gnaq 3 0.02 0.26 1.63
175 INT168681 Gene_expression of BMS1 5 0.37 2.7 1.62
176 INT94827 Gene_expression of HBS1L 24 0.67 26.11 1.61
177 INT35526 Binding of Eef1a2 14 0.34 5.82 1.61
178 INT145201 Negative_regulation of Binding of Rab38 1 0.37 0.06 1.61
179 INT240059 Binding of RHOB 7 0.48 3.96 1.59
180 INT6438 Positive_regulation of RAN 6 0.42 2.09 1.59
181 INT80890 Negative_regulation of Phosphorylation of ADCY1 2 0.36 0.24 1.57
182 INT71999 Negative_regulation of Gene_expression of Gnaq 3 0.41 0.08 1.56
183 INT72310 Regulation of Regulation of ADCY1 6 0.24 1.24 1.55
184 INT128170 Gene_expression of Gna12 1 0.01 0 1.54
185 INT93624 Negative_regulation of Kras 3 0.41 1.15 1.52
186 INT9953 Positive_regulation of Gnas 10 0.34 3.21 1.51
187 INT146190 Negative_regulation of Localization of Rhoa 4 0.42 1.64 1.5
188 INT72008 Gene_expression of Gnai2 4 0.38 0.42 1.49
189 INT104694 Positive_regulation of Localization of TUBA4A 1 0.00 2.71 1.49
190 INT113785 Negative_regulation of Eef1a2 15 0.31 1.33 1.48
191 INT317187 Positive_regulation of BMS1 1 0.04 0.98 1.48
192 INT121347 Binding of GNAS 8 0.13 3.99 1.47
193 INT145229 Gene_expression of Rras 4 0.25 3.2 1.47
194 INT54190 Binding of Gnai1 2 0.34 0.28 1.47
195 INT184206 Protein_catabolism of HRAS 22 0.66 7.86 1.46
196 INT94639 Negative_regulation of Gene_expression of Gnai1 1 0.02 0.08 1.46
197 INT18493 Localization of Eef1a1 4 0.70 0.18 1.45
198 INT93860 Gene_expression of Srl 4 0.67 2.22 1.44
199 INT254072 Gene_expression of SEPT5 23 0.16 8.29 1.43
200 INT16227 Regulation of Rit2 3 0.62 0.24 1.43
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