GOS:cell cycle

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This page displays the top molecular interactions and top single events that were mentioned in the literature for cell cycle. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cell cycle. They are ordered first by their pain relevance and then by number of times they were reported for cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Genes linked to cell cycle Documents TM Confidence Disease Relevance Pain Relevance
1 INT338167 Binding of CDKN2A and MC1R 1 1 0.42 6.14 5.76
2 INT143946 Binding of Pebp1 and Mastl 1 1 0.00 2.04 3.82
3 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 1 2 0.46 0.75 2.61
4 INT287746 Anxa1 Positive_regulation of Gene_expression of Lpar1 1 1 0.07 1.72 2.46
5 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 1 0.19 3.22 2.35
6 INT134872 Binding of Calm3 and IQCJ 1 1 0.00 0.82 2.26
7 INT281084 Prkaca Positive_regulation of Mapk1 1 2 0.25 0 2.06
8 INT227493 Binding of TCEA1 and SIRT2 1 1 0.01 1.55 1.93
9 INT207630 Binding of Calm3 and Nrgn 1 1 0.06 1.03 1.82
10 INT144280 ACP1 Negative_regulation of Phosphorylation of MAPK1 1 1 0.37 0.78 1.56
11 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 1 0.22 1.11 1.54
12 INT93781 Racgap1 Positive_regulation of Positive_regulation of Gnptab 1 1 0.02 0.07 1.49
13 INT93782 Racgap1 Positive_regulation of Rgs9 1 1 0.55 0.07 1.49
14 INT93783 Racgap1 Positive_regulation of Gnptab 1 1 0.02 0.07 1.49
15 INT73650 Binding of Pim3 and Creb1 1 1 0.03 2.48 1.47
16 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 1 0.02 0 1.46
17 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 1 0.39 1.04 1.45
18 INT261831 Mapk1 Negative_regulation of Hspg2 1 1 0.00 1.26 1.42
19 INT148450 Gene_expression of Inhbe Positive_regulation of Mapk1 1 1 0.07 1.35 1.41
20 INT161670 H2-M3 Positive_regulation of Positive_regulation of Mapk1 1 1 0.14 0.73 1.41
21 INT106062 Positive_regulation of Oprl1 Positive_regulation of Mapk1 1 1 0.13 0.16 1.35
22 INT106071 Positive_regulation of Oprl1 Positive_regulation of MAPK3 1 1 0.12 0.16 1.34
23 INT145473 Mastl Positive_regulation of Dnahc8 1 1 0.07 0.06 1.33
24 INT198957 Binding of Cnr1 and Mastl 1 1 0.00 0 1.31
25 INT261841 Mastl Positive_regulation of Trpa1 1 1 0.00 0.82 1.3
26 INT113844 CDKN1A Negative_regulation of CDK2 2 4 0.49 1.18 1.27
27 INT100816 PPP1R14C Regulation of Ppp1cc 1 1 0.08 0 1.27
28 INT87026 ZAK Positive_regulation of Gene_expression of IL12A 1 3 0.12 2.55 1.26
29 INT73710 Mastl Positive_regulation of Localization of Oprl1 1 1 0.02 0 1.26
30 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 1 0.11 0 1.25
31 INT162163 CDKN2A Positive_regulation of PLD2 1 1 0.24 0 1.24
32 INT249487 Binding of Ephb1 and Src 1 1 0.17 0.74 1.23
33 INT52955 Binding of Slc6a3 and Pdpn 2 1 0.17 1.11 1.22
34 INT166388 Binding of Gnb2l1 and Mapk1 2 1 0.49 0.49 1.21
35 INT299299 VEGFA Positive_regulation of SRC 1 1 0.20 0.91 1.2
36 INT70288 Negative_regulation of Atxn2l Positive_regulation of Racgap1 1 1 0.02 0.3 1.19
37 INT139736 Htr1a Positive_regulation of Mapk3 1 1 0.54 0.13 1.19
38 INT121191 KCNMA1 Positive_regulation of Phosphorylation of MAPK1 1 1 0.06 0.61 1.18
39 INT150835 Gper Positive_regulation of Localization of Prkce 1 1 0.15 0.62 1.18
40 INT134871 Negative_regulation of Binding of Calm3 and IQCJ 1 1 0.00 0.41 1.17
41 INT146352 Binding of Rgs14 and Mors1 1 1 0.23 0.27 1.17
42 INT169557 Cacna1h Positive_regulation of Mapk1 1 1 0.07 0.91 1.17
43 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 1 0.19 1.61 1.17
44 INT161510 Tlr4 Positive_regulation of Mapk1 1 1 0.14 0.3 1.16
45 INT70289 Atxn2l Positive_regulation of Racgap1 1 1 0.04 0.29 1.15
46 INT196812 Ppp1r1b Negative_regulation of Ppp1cc 1 3 0.07 0.13 1.12
47 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 1 0.23 0.68 1.12
48 INT109374 Ppp1cc Negative_regulation of Ppp2r1a 1 1 0.24 0 1.11
49 INT134870 Regulation of Binding of Calm3 and Nav1 1 1 0.17 0.42 1.1
50 INT134869 Binding of Calm3 and Nav1 1 1 0.31 0.42 1.1
51 INT164378 MAPK3 Positive_regulation of Transcription of PDYN 1 1 0.50 0.2 1.09
52 INT164382 MAPK3 Positive_regulation of Gene_expression of Fos 1 1 0.75 0.2 1.08
53 INT164383 Positive_regulation of MAPK3 Positive_regulation of Gene_expression of Fos 1 1 0.54 0.2 1.08
54 INT96905 Plxna3 Regulation of Regulation of Prkce 1 1 0.18 0.71 1.07
55 INT329962 Binding of C5 and HEPACAM 1 1 0.03 2.25 1.06
56 INT73311 Binding of Oprm1 and Pdpn 2 1 0.08 0.71 1.06
57 INT329959 Binding of TRAF1 and HEPACAM 1 1 0.03 2.25 1.06
58 INT317552 Binding of Calm3 and Car2 1 2 0.06 0.07 1.05
59 INT352456 Dusp1 Negative_regulation of Mapk14 1 1 0.03 1.31 1.03
60 INT101067 MAP3K15 Positive_regulation of MAPK1 1 1 0.21 0.47 1.03
61 INT225158 Binding of CDK2 and CDKN1A 2 7 0.30 3.26 1.02
62 INT87025 ZAK Positive_regulation of Gene_expression of IL6 1 2 0.11 1.59 1.02
63 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 1 0.46 1.03 1.02
64 INT121743 Negative_regulation of Src Negative_regulation of Ephb1 1 1 0.27 0 1.02
65 INT317518 Src Regulation of Negative_regulation of Oprm1 1 1 0.16 0.07 1
66 INT221747 Gtf3a Positive_regulation of Positive_regulation of Racgap1 1 1 0.00 0.33 1
67 INT143915 Src Regulation of Rbm39 1 1 0.03 0.18 0.99
68 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 1 0.26 0.63 0.98
69 INT121744 Src Positive_regulation of Positive_regulation of Ephb1 1 1 0.35 0 0.96
70 INT166842 Binding of ANXA1 and Nfkb1 1 1 0.37 1.64 0.95
71 INT22726 Positive_regulation of Ahr Positive_regulation of Hrtrt1 2 1 0.22 0.18 0.95
72 INT22725 Ahr Positive_regulation of Hrtrt1 2 1 0.22 0.18 0.95
73 INT100018 TNF Positive_regulation of MAPK1 1 3 0.24 1.56 0.94
74 INT41617 Sp5 Positive_regulation of Mlf1 1 1 0.02 0.25 0.94
75 INT144281 ACP1 Negative_regulation of Positive_regulation of MAPK1 1 1 0.27 0.58 0.94
76 INT102554 HGF Positive_regulation of Phosphorylation of RPS6KA1 1 1 0.21 0.93 0.94
77 INT144285 ACP1 Negative_regulation of MAPK1 1 1 0.37 0.58 0.93
78 INT223871 Ltp Positive_regulation of Gene_expression of Mapk1 1 1 0.33 0 0.93
79 INT65462 Bri3 Negative_regulation of Racgap1 1 1 0.02 0.39 0.93
80 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 1 0.27 0.44 0.92
81 INT352465 Dusp1 Negative_regulation of Gene_expression of Mapk14 1 1 0.03 1.09 0.92
82 INT302828 Mapkapk5 Positive_regulation of Mapk1 1 1 0.07 1.38 0.91
83 INT135446 Map2k1 Positive_regulation of Mapk3 1 1 0.54 0.25 0.91
84 INT352444 Dusp1 Negative_regulation of Phosphorylation of Mapk14 1 1 0.03 1.09 0.91
85 INT343918 IgG Positive_regulation of Phosphorylation of MAPK1 1 1 0.01 3.57 0.91
86 INT109842 Prkce Positive_regulation of Localization of Trpv1 1 1 0.13 1.31 0.91
87 INT54202 Gnai1 Negative_regulation of Binding of Pag1 and Agp2 1 1 0.01 0.18 0.91
88 INT122266 Src Negative_regulation of Grin2b 1 1 0.27 0.43 0.91
89 INT54200 Gnai1 Negative_regulation of Pag1 1 1 0.05 0.18 0.9
90 INT54197 Binding of Gnai1 and Pag1 1 1 0.04 0.18 0.9
91 INT54187 Gnai1 Negative_regulation of Binding of Oprd1 and Pag1 1 1 0.00 0.18 0.9
92 INT168281 Tlr4 Positive_regulation of Phosphorylation of Mapk4 1 1 0.06 1.05 0.89
93 INT92404 PSRC1 Regulation of CDKN1A 3 1 0.33 0.66 0.89
94 INT188196 LIF Regulation of MAPK1 1 1 0.21 2.26 0.87
95 INT97738 Mdk Positive_regulation of Mapk3 1 1 0.08 0.66 0.87
96 INT188214 OSM Regulation of MAPK1 1 1 0.20 2.27 0.87
97 INT97735 Trib3 Positive_regulation of Mapk3 1 1 0.05 0.66 0.87
98 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 1 0.01 0.5 0.87
99 INT116107 CDK4 Positive_regulation of Phosphorylation of EID1 2 1 0.01 0.32 0.86
100 INT133176 Regulation of Mastl Negative_regulation of Il12a 1 1 0.01 0.24 0.86
101 INT166634 Binding of Bcl2 and Becn1 1 1 0.20 0.5 0.86
102 INT133177 Mastl Negative_regulation of Il12a 1 1 0.01 0.24 0.86
103 INT306831 Positive_regulation of Binding of E2F4 and NOLC1 1 1 0.10 0.46 0.85
104 INT190183 MAPK1 Regulation of CDCP1 1 1 0.00 1.19 0.85
105 INT306826 Binding of E2F4 and NOLC1 1 1 0.08 0.41 0.84
106 INT340115 Comt Regulation of Localization of Dusp1 1 1 0.12 0.83 0.83
107 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 1 0.36 0.51 0.83
108 INT97058 Cpz Regulation of Gene_expression of Trp53 1 1 0.27 0.57 0.83
109 INT317513 Oprm1 Regulation of Positive_regulation of Src 1 1 0.09 0.4 0.82
110 INT317570 Oprm1 Regulation of Src 1 1 0.04 0.4 0.82
111 INT322266 Binding of LIG4 and NOS3 1 1 0.02 2.35 0.82
112 INT262572 Ngf Positive_regulation of Mapk1 1 2 0.04 0.52 0.81
113 INT103178 Mastl Positive_regulation of Localization of Calca 1 1 0.13 0.36 0.81
114 INT161520 H2-M3 Regulation of Positive_regulation of Mapk1 1 1 0.09 0.47 0.79
115 INT132977 Tac1 Positive_regulation of Mapk1 1 1 0.06 0.17 0.79
116 INT117909 Mastl Positive_regulation of Mapk1 2 1 0.04 0 0.79
117 INT110518 Tnf Positive_regulation of Prkce 1 1 0.26 1.43 0.78
118 INT128180 Gna12 Regulation of Regulation of RHOA 1 1 0.00 0 0.78
119 INT181615 SRC Positive_regulation of IRS1 1 1 0.01 0.98 0.77
120 INT163830 ERBB2 Positive_regulation of MAPK1 1 1 0.06 1.63 0.76
121 INT155096 Stat3 Regulation of Mapk3 1 1 0.36 0.45 0.76
122 INT117412 RYBP Negative_regulation of LIG4 1 1 0.00 0.42 0.76
123 INT133675 NPY6R Negative_regulation of SRC 1 1 0.17 0.75 0.74
124 INT93709 Positive_regulation of Oprd1 Regulation of Calm3 1 1 0.01 0 0.74
125 INT93708 Oprd1 Regulation of Calm3 1 1 0.01 0 0.73
126 INT93710 Oprm1 Positive_regulation of Gene_expression of Calm3 1 1 0.25 0 0.73
127 INT128404 Mapk1 Positive_regulation of Phosphorylation of Gja1 1 1 0.65 0.73 0.73
128 INT106992 F2 Positive_regulation of PARD3 1 3 0.05 1.83 0.72
129 INT317547 Src Positive_regulation of Positive_regulation of Grin1 1 1 0.17 0 0.72
130 INT148453 Gene_expression of Inhbe Positive_regulation of Src 1 1 0.06 0.68 0.72
131 INT126304 Binding of Rgs2 and Pag1 1 1 0.16 0.41 0.72
132 INT168911 Grm5 Regulation of Mapk3 1 1 0.17 0.78 0.71
133 INT134476 Cdk5 Regulation of Map2k1 2 1 0.69 0.88 0.71
134 INT107933 Oprm1 Positive_regulation of Gene_expression of Mastl 1 1 0.33 0.61 0.71
135 INT155610 FPR1 Positive_regulation of Phosphorylation of SGSM3 1 1 0.04 0.68 0.71
136 INT142994 Binding of UPF1 and FCMTE1 1 1 0.00 0.91 0.7
137 INT166386 Mapk1 Regulation of Gene_expression of Gnb2l1 2 1 0.46 0.25 0.7
138 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 1 0.04 1.21 0.7
139 INT329957 Binding of STAT4 and HEPACAM 1 1 0.03 1.41 0.7
140 INT194685 MAPK1 Regulation of Gene_expression of IL10 1 1 0.06 1.18 0.7
141 INT320634 Positive_regulation of MAPK1 Regulation of PBX2 1 1 0.03 1.21 0.7
142 INT303691 KNG1 Positive_regulation of AHR 1 1 0.03 0.98 0.69
143 INT278077 Binding of BPHL and AURKC 1 1 0.16 4.29 0.69
144 INT340116 Dusp1 Regulation of Transcription of Oprm1 1 1 0.12 0.71 0.69
145 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 1 0.03 0.99 0.69
146 INT223868 Mapk1 Positive_regulation of Creb1 1 2 0.17 0.34 0.68
147 INT223876 Mapk1 Positive_regulation of Atf6b 1 1 0.10 0 0.68
148 INT194410 Binding of CALCA and LZTS1 1 1 0.06 0 0.67
149 INT211915 Fig4 Positive_regulation of Mapk3 1 1 0.12 0.25 0.66
150 INT118568 Binding of Ddit3 and Atf6 1 1 0.33 0.85 0.66
151 INT88194 ZAK Positive_regulation of Gene_expression of IL1B 1 1 0.07 0.94 0.66
152 INT211916 Fig4 Positive_regulation of Mapk1 1 1 0.13 0.25 0.66
153 INT191332 AMPH Positive_regulation of Mapk1 1 1 0.76 0 0.66
154 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 1 0.20 0.63 0.66
155 INT213895 Mastl Regulation of Gene_expression of Cnr1 1 1 0.17 0.26 0.66
156 INT124477 MAP2K1 Positive_regulation of Positive_regulation of MAPK1 1 1 0.12 1.35 0.65
157 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 1 0.44 0.06 0.65
158 INT148173 Positive_regulation of Grm5 Positive_regulation of Phosphorylation of Mapk1 1 1 0.01 0.45 0.65
159 INT100806 Ppp1r14a Regulation of Ppp1cc 1 1 0.05 0 0.65
160 INT112513 Binding of Prkaca and Prkce 1 1 0.04 0.4 0.64
161 INT253585 Binding of IFN1@ and Csnk2a2 1 1 0.24 1.35 0.64
162 INT112516 Binding of Prkce and Trib3 1 1 0.01 0.4 0.64
163 INT112870 Aap Positive_regulation of Gene_expression of Ccnd1 1 1 0.24 0.34 0.63
164 INT169296 PTPLA Positive_regulation of MAPK3 1 1 0.10 0.15 0.63
165 INT334594 Binding of GNAI1 and MRGPRD 1 1 0.01 0.19 0.63
166 INT281092 Adcy1 Positive_regulation of Mapk1 1 1 0.21 0 0.63
167 INT281090 Prkacb Positive_regulation of Mapk1 1 1 0.06 0 0.62
168 INT218837 Ppp1cc Regulation of Ltp 1 1 0.13 1.19 0.62
169 INT218835 Ppp1cc Regulation of Cysltr1 1 1 0.01 1.19 0.62
170 INT96945 Hrh1 Negative_regulation of Spdya 1 1 0.00 0.32 0.62
171 INT2687 Negative_regulation of Binding of Thra and SGSM3 1 1 0.43 0.1 0.62
172 INT218833 Binding of Ppp1cc and Regulation of Ltp 1 1 0.13 1.2 0.62
173 INT218836 Binding of Ppp1cc and Regulation of Cysltr1 1 1 0.01 1.2 0.62
174 INT166398 CDKN1B Regulation of Gene_expression of CDKN1A 2 1 0.46 0.83 0.61
175 INT166399 CDKN1A Regulation of Gene_expression of CDKN1B 2 1 0.46 0.83 0.61
176 INT166395 CDKN1A Regulation of Gene_expression of IFI27 1 1 0.32 0.83 0.61
177 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 1 0.27 0.83 0.61
178 INT166392 IFI27 Regulation of Gene_expression of CDKN1A 1 1 0.32 0.83 0.61
179 INT2686 Binding of Thra and SGSM3 1 1 0.36 0.1 0.61
180 INT166387 Binding of Gnb2l1 and Mdk 1 1 0.30 0.24 0.61
181 INT92403 PSRC1 Regulation of Positive_regulation of CDKN1A 3 1 0.33 0.45 0.6
182 INT166385 Binding of Araf and Gnb2l1 1 1 0.23 0.24 0.6
183 INT218845 Ppp1cc Positive_regulation of Positive_regulation of Cysltr1 1 1 0.02 0.92 0.6
184 INT208372 Il13 Positive_regulation of Ahr 2 1 0.21 1.22 0.59
185 INT142993 Serpinc1 Positive_regulation of Phosphorylation of RHOA 1 1 0.05 0.05 0.59
186 INT352463 Gse1 Regulation of Gene_expression of Dusp1 1 1 0.07 0 0.59
187 INT77376 Tmie Negative_regulation of Mastl 1 1 0.01 0 0.59
188 INT223158 Mapk3 Regulation of Gene_expression of Mapk14 1 1 0.48 1.33 0.59
189 INT250054 Positive_regulation of Binding of Gpr143 and Spdya 1 1 0.04 0.52 0.59
190 INT250053 Binding of Gpr143 and Spdya 1 1 0.03 0.51 0.59
191 INT87024 Positive_regulation of ZAK Positive_regulation of Localization of IFNG 1 2 0.05 0.81 0.58
192 INT73654 Binding of Jun and Pim3 1 1 0.02 0.99 0.58
193 INT291262 Positive_regulation of INS Positive_regulation of Mapk1 1 1 0.03 1.78 0.58
194 INT100225 Binding of Egf and Src 1 1 0.01 0.67 0.58
195 INT291258 INS Positive_regulation of Mapk1 1 1 0.04 1.77 0.58
196 INT115146 MAPK1 Positive_regulation of EGR1 1 3 0.13 2.43 0.57
197 INT148172 Mapk1 Positive_regulation of Phosphorylation of Kcnd2 1 1 0.49 0.55 0.57
198 INT299263 PTPN3 Negative_regulation of VEGFA Positive_regulation of SRC 1 1 0.03 0.35 0.57
199 INT141362 EP300 Negative_regulation of Transcription of IL2 1 1 0.17 0 0.56
200 INT73920 Binding of CCNT1 and CYP2B6 1 1 0.19 0.17 0.56

Single Events

The table below shows the top 100 pain related interactions that have been reported for cell cycle. They are ordered first by their pain relevance and then by number of times they were reported in cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94
2 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27
3 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46
4 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72
5 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17
6 INT92437 Positive_regulation of Phosphorylation of Mapk1 113 0.70 32.19 40.29
7 INT114751 Gene_expression of Mapk1 137 0.76 60.14 39.98
8 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37
9 INT48933 Gene_expression of Mapk3 93 0.75 44.39 37.92
10 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05
11 INT48924 Positive_regulation of Mapk3 107 0.67 50.53 34.05
12 INT48925 Gene_expression of Mapk1 95 0.74 42.21 32.91
13 INT117112 Negative_regulation of Mapk1 87 0.56 40.34 31.18
14 INT46833 Positive_regulation of SGSM3 56 0.67 24.49 30.31
15 INT72375 Phosphorylation of Mapk3 87 0.80 43.66 30.27
16 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85
17 INT95788 Positive_regulation of Positive_regulation of Mapk1 83 0.69 24.75 25.84
18 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58
19 INT71781 Phosphorylation of MAPK3 62 0.80 27.73 23.73
20 INT292049 Gene_expression of Csnk1a1 1 0.59 28.22 19.53
21 INT12725 Positive_regulation of Racgap1 66 0.68 32.74 19.29
22 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99
23 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3
24 INT71787 Positive_regulation of MAPK3 37 0.67 17.5 17.88
25 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
26 INT95790 Regulation of Mapk1 55 0.61 21.17 16.31
27 INT111462 Negative_regulation of Phosphorylation of Mapk1 45 0.57 19.49 15.59
28 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42
29 INT128401 Positive_regulation of Positive_regulation of Mapk1 39 0.70 10.88 15.38
30 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32
31 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74
32 INT80688 Positive_regulation of Positive_regulation of MAPK1 72 0.69 39.35 14.11
33 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99
34 INT111529 Phosphorylation of Mapk3 41 0.80 21.14 13.72
35 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61
36 INT75521 Positive_regulation of Positive_regulation of SGSM3 13 0.67 7.99 13.54
37 INT30117 Gene_expression of Calm1 18 0.71 17.45 13.18
38 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
39 INT48927 Regulation of Mapk3 25 0.60 14.06 12.82
40 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
41 INT150676 Positive_regulation of Gene_expression of Mapk1 30 0.45 10.06 12.37
42 INT119396 Regulation of Positive_regulation of Mapk1 22 0.61 7.88 12.25
43 INT146197 Positive_regulation of Rhoa 60 0.68 34.12 12.02
44 INT10654 Negative_regulation of SGSM3 31 0.57 12.24 11.7
45 INT88650 Negative_regulation of Prkce 13 0.57 11.93 11.16
46 INT75525 Negative_regulation of Positive_regulation of MAPK1 40 0.59 25.15 11.15
47 INT48921 Regulation of Mapk1 25 0.49 19.51 10.41
48 INT87451 Positive_regulation of Mapk3 34 0.67 12.82 10.38
49 INT91948 Positive_regulation of Prkce 16 0.64 11.36 10.32
50 INT790 Gene_expression of Mastl 22 0.68 4.56 10.23
51 INT73223 Gene_expression of UPF1 78 0.41 31.44 9.94
52 INT62269 Gene_expression of Cdkn1a 60 0.73 35.78 9.84
53 INT113667 Positive_regulation of Mapk7 15 0.70 12.24 9.72
54 INT62544 Gene_expression of Anxa1 21 0.47 13.56 9.71
55 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69
56 INT159116 Gene_expression of Gnb2l1 12 0.77 2.79 9.49
57 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25
58 INT94196 Negative_regulation of Phosphorylation of MAPK1 60 0.59 31.64 9.16
59 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
60 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01
61 INT128159 Positive_regulation of DDIT3 29 0.67 29.5 8.99
62 INT109432 Negative_regulation of Phosphorylation of Mapk1 19 0.54 7.01 8.98
63 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
64 INT111133 Negative_regulation of Mapk3 31 0.57 10.89 8.9
65 INT232307 Localization of Calm1 5 0.74 9.99 8.71
66 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
67 INT126848 Positive_regulation of Phosphorylation of Mapk1 30 0.50 15.94 8.34
68 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
69 INT71785 Gene_expression of MAPK3 22 0.75 11.35 8.21
70 INT60285 Negative_regulation of Racgap1 27 0.56 21.71 8.14
71 INT116707 Positive_regulation of Mapk4 8 0.21 9.83 7.96
72 INT82762 Positive_regulation of Positive_regulation of Mapk3 23 0.67 7.72 7.91
73 INT116706 Phosphorylation of Mapk4 9 0.25 8.5 7.79
74 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73
75 INT72372 Positive_regulation of Phosphorylation of Mapk3 30 0.67 13.6 7.69
76 INT91618 Positive_regulation of Phosphorylation of MAPK3 21 0.67 7.99 7.65
77 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47
78 INT92138 Binding of CDKN2A 28 0.37 25.64 7.47
79 INT102572 Gene_expression of Ccnd1 79 0.69 56.37 7.34
80 INT13348 Negative_regulation of Mastl 11 0.36 3.33 7.28
81 INT82610 Positive_regulation of SRC 53 0.67 26.89 7.27
82 INT106757 Gene_expression of Dusp1 9 0.66 10.45 7.26
83 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
84 INT195969 Binding of Khdrbs1 1 0.36 1.62 7.19
85 INT55957 Positive_regulation of PRNP 57 0.67 37.87 7.11
86 INT90275 Negative_regulation of Ppp1cc 29 0.58 1.91 7.11
87 INT87644 Phosphorylation of SGSM3 12 0.80 2.08 7.04
88 INT166383 Positive_regulation of Gene_expression of Gnb2l1 1 0.69 2.19 7.02
89 INT134864 Binding of Calm3 20 0.27 1.86 6.86
90 INT73709 Binding of Mastl 11 0.40 3.39 6.76
91 INT48928 Positive_regulation of Gene_expression of Mapk1 19 0.48 9.38 6.59
92 INT292062 Negative_regulation of Csnk1a1 1 0.44 7.57 6.52
93 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
94 INT94197 Negative_regulation of Phosphorylation of MAPK3 13 0.57 5.51 6.18
95 INT48926 Positive_regulation of Gene_expression of Mapk3 12 0.46 6.02 6.13
96 INT139964 Regulation of Phosphorylation of Mapk1 12 0.58 10.04 6.1
97 INT20899 Negative_regulation of GNAI1 12 0.57 4.24 6.07
98 INT178604 Gene_expression of TPX2 13 0.37 20.29 6.04
99 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
100 INT130111 Regulation of Positive_regulation of MAPK1 14 0.36 11.01 5.9
101 INT104330 Negative_regulation of CDKN1A 57 0.58 39.93 5.88
102 INT158672 Positive_regulation of Calm1 10 0.44 4.79 5.86
103 INT62270 Positive_regulation of Gene_expression of Cdkn1a 30 0.47 18.73 5.69
104 INT159115 Negative_regulation of Gene_expression of Gnb2l1 3 0.42 1.33 5.59
105 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56
106 INT101604 Regulation of Cdk5 10 0.61 2.2 5.53
107 INT82611 Negative_regulation of SRC 30 0.57 20.16 5.47
108 INT91946 Regulation of Prkce 6 0.44 4.13 5.46
109 INT71779 Positive_regulation of Gene_expression of MAPK1 27 0.47 21.41 5.39
110 INT99487 Negative_regulation of MAPK3 15 0.57 7.13 5.39
111 INT292072 Positive_regulation of Gene_expression of Csnk1a1 1 0.53 9.76 5.39
112 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38
113 INT100222 Binding of Src 9 0.26 5.41 5.37
114 INT92571 Regulation of Mapk7 8 0.54 4.8 5.25
115 INT106756 Positive_regulation of Gene_expression of Dusp1 7 0.59 7.65 5.24
116 INT75250 Negative_regulation of Positive_regulation of SGSM3 5 0.57 2.47 5.24
117 INT46281 Binding of Calm1 8 0.48 5.54 5.22
118 INT111100 Gene_expression of Dusp1 18 0.76 14.81 5.21
119 INT134468 Gene_expression of Cdk5r1 26 0.48 27.09 5.2
120 INT99549 Gene_expression of CDKN1B 30 0.75 17 5.15
121 INT128161 Gene_expression of DDIT3 20 0.75 17.14 5.13
122 INT61312 Positive_regulation of Spdya 3 0.10 0.74 5.12
123 INT116150 Positive_regulation of Ddit3 26 0.67 22.58 5.01
124 INT162365 Gene_expression of Map3k8 33 0.58 22.75 4.95
125 INT89844 Positive_regulation of Phosphorylation of Src 10 0.43 4.71 4.95
126 INT109838 Phosphorylation of Prkce 6 0.67 5.26 4.95
127 INT100220 Negative_regulation of Src 13 0.41 6.37 4.93
128 INT116464 Negative_regulation of Birc5 53 0.59 45.4 4.91
129 INT116710 Positive_regulation of Phosphorylation of Mapk4 4 0.11 5.45 4.85
130 INT160055 Localization of CDKN1A 15 0.78 12.56 4.83
131 INT52952 Binding of Pdpn 8 0.13 3.57 4.79
132 INT62920 Regulation of Gnai1 3 0.52 0.08 4.78
133 INT92572 Gene_expression of Mapk7 17 0.78 3.71 4.76
134 INT128178 Positive_regulation of RHOA 59 0.68 9.3 4.7
135 INT17391 Gene_expression of GNAI1 11 0.75 5.26 4.7
136 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
137 INT17393 Positive_regulation of GNAI1 17 0.49 2.42 4.66
138 INT98453 Positive_regulation of Src 19 0.47 7.84 4.62
139 INT159122 Positive_regulation of Gnb2l1 8 0.69 2.2 4.61
140 INT60758 Gene_expression of Prkce 8 0.20 4.12 4.59
141 INT292060 Positive_regulation of Csnk1a1 1 0.53 6.03 4.57
142 INT29326 Gene_expression of Calm1 17 0.67 3.71 4.53
143 INT2213 Regulation of EP300 10 0.54 4.72 4.5
144 INT75530 Regulation of SGSM3 11 0.60 7.22 4.48
145 INT34263 Positive_regulation of Mastl 8 0.35 1.36 4.35
146 INT92570 Negative_regulation of Mapk7 6 0.53 2.53 4.34
147 INT292057 Regulation of Csnk1a1 1 0.34 3.52 4.33
148 INT118565 Gene_expression of Ddit3 35 0.75 23.62 4.32
149 INT111535 Negative_regulation of Phosphorylation of Mapk3 9 0.57 6.39 4.31
150 INT109219 Negative_regulation of Cdk5r1 5 0.43 1.22 4.25
151 INT158416 Localization of Mapk1 19 0.67 5.32 4.18
152 INT119063 Gene_expression of BRCA1 24 0.67 30.04 4.17
153 INT14165 Negative_regulation of Ahr 14 0.51 8.35 4.17
154 INT37615 Gene_expression of ESCO1 6 0.72 1.1 4.15
155 INT38859 Gene_expression of SGSM3 14 0.75 12.98 4.09
156 INT182311 Positive_regulation of Birc5 26 0.67 25.32 4.08
157 INT133244 Regulation of Positive_regulation of Mapk1 11 0.43 3.52 4.03
158 INT109861 Gene_expression of Rhoa 11 0.78 5.67 4.02
159 INT59836 Positive_regulation of Upf1 24 0.02 4.42 3.99
160 INT112782 Localization of Mapk3 8 0.78 1.87 3.98
161 INT116709 Negative_regulation of Mapk4 5 0.10 4.48 3.97
162 INT88414 Negative_regulation of CDK2 30 0.57 18.4 3.96
163 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95
164 INT148495 Regulation of Cdk5 6 0.58 5.42 3.95
165 INT93707 Positive_regulation of Calm3 9 0.65 1.62 3.9
166 INT94303 Gene_expression of Upf1 44 0.04 11.62 3.87
167 INT113924 Binding of Mapk1 27 0.38 8.64 3.84
168 INT123827 Positive_regulation of Phosphorylation of Mapk3 10 0.67 5.22 3.82
169 INT94291 Regulation of Gene_expression of Mapk3 4 0.40 3.05 3.8
170 INT1167 Regulation of Mastl 7 0.53 1.86 3.77
171 INT146350 Phosphorylation of Rgs14 1 0.80 0.79 3.77
172 INT162366 Positive_regulation of Map3k8 24 0.50 15.69 3.71
173 INT78514 Gene_expression of Cast 6 0.64 4.48 3.69
174 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
175 INT85497 Gene_expression of Anxa1 6 0.77 4.7 3.68
176 INT93399 Gene_expression of Ccnd1 38 0.58 21 3.65
177 INT122327 Regulation of Src 6 0.59 0.59 3.6
178 INT88197 Binding of ZAK 9 0.46 6.23 3.54
179 INT115921 Positive_regulation of AHR 22 0.49 12.03 3.53
180 INT142483 Positive_regulation of Gene_expression of DDIT3 15 0.67 11.39 3.47
181 INT109840 Localization of Prkce 5 0.74 3.01 3.45
182 INT162307 Gene_expression of Mapk4 2 0.23 2.89 3.44
183 INT122997 Phosphorylation of Rps6kb1 46 0.72 9.92 3.43
184 INT85233 Localization of SGSM3 11 0.78 10.91 3.41
185 INT109424 Positive_regulation of Rgs2 1 0.67 0.26 3.41
186 INT55259 Negative_regulation of Calm2 9 0.49 1.87 3.4
187 INT12639 Gene_expression of Gnai2 6 0.24 0.35 3.4
188 INT79270 Gene_expression of MKI67 113 0.77 63.52 3.38
189 INT52839 Regulation of Racgap1 14 0.25 9.46 3.37
190 INT106760 Positive_regulation of Dusp1 16 0.59 8.5 3.35
191 INT129751 Regulation of Phosphorylation of Mapk3 11 0.55 3.91 3.35
192 INT162368 Negative_regulation of Map3k8 17 0.42 7.96 3.34
193 INT82796 Regulation of CDKN1A 22 0.53 9.83 3.33
194 INT137350 Phosphorylation of Src 13 0.45 4.14 3.32
195 INT97737 Negative_regulation of Phosphorylation of Mapk3 9 0.57 5.64 3.3
196 INT78471 Regulation of Gene_expression of CDKN2A 13 0.45 12.52 3.28
197 INT62547 Positive_regulation of Gene_expression of Anxa1 5 0.42 4.52 3.27
198 INT62268 Positive_regulation of Cdkn1a 33 0.67 14.12 3.26
199 INT116078 Positive_regulation of Phosphorylation of SGSM3 4 0.67 0.09 3.24
200 INT60174 Positive_regulation of Pik3c3 12 0.67 1.05 3.23
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