GOS:chromosome

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This page displays the top molecular interactions and top single events that were mentioned in the literature for chromosome. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for chromosome. They are ordered first by their pain relevance and then by number of times they were reported for chromosome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Genes linked to chromosome Documents TM Confidence Disease Relevance Pain Relevance
1 INT322411 Hist1h1t Positive_regulation of Positive_regulation of OPRM1 1 1 0.00 1.25 3.63
2 INT229497 Binding of Vim and Ndel1 1 1 0.33 3.5 2.81
3 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 1 2 0.02 0.44 2.79
4 INT322410 Hist1h1t Positive_regulation of Phosphorylation of OPRM1 1 1 0.00 0.08 2.31
5 INT215100 Binding of Hmgb1 and Tlr4 1 5 0.29 3.21 1.68
6 INT215096 Binding of Hmgb1 and Tlr2 1 9 0.38 11.61 1.61
7 INT28992 Tmpo Positive_regulation of Pomc 1 1 0.36 3.18 1.41
8 INT229496 Binding of Ndel1 and Gopc 1 1 0.08 2.05 1.36
9 INT136200 Binding of Penk and NUP37 1 1 0.04 0 1.28
10 INT100816 PPP1R14C Regulation of Ppp1cc 1 1 0.08 0 1.27
11 INT350862 Hist1h1t Regulation of Kcnj5 1 1 0.02 1.35 1.22
12 INT196812 Ppp1r1b Negative_regulation of Ppp1cc 1 3 0.07 0.13 1.12
13 INT109374 Ppp1cc Negative_regulation of Ppp2r1a 2 1 0.24 0 1.11
14 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 1 2 0.05 1.85 1.06
15 INT145163 Tlr4 Positive_regulation of Localization of Nsfl1c 1 1 0.02 0.43 0.94
16 INT253759 Hmgb1 Positive_regulation of Apex1 1 1 0.09 4.53 0.69
17 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 1 0.32 2.9 0.68
18 INT100806 Ppp1r14a Regulation of Ppp1cc 1 1 0.05 0 0.65
19 INT206206 Binding of Mcf2l and Obfc1 1 1 0.02 1.11 0.64
20 INT218837 Ppp1cc Regulation of Ltp 1 1 0.13 1.19 0.62
21 INT218835 Ppp1cc Regulation of Cysltr1 1 1 0.01 1.19 0.62
22 INT218833 Binding of Ppp1cc and Regulation of Ltp 1 1 0.13 1.2 0.62
23 INT218836 Binding of Ppp1cc and Regulation of Cysltr1 1 1 0.01 1.2 0.62
24 INT285939 IL6 Positive_regulation of TEP1 1 1 0.01 1.76 0.61
25 INT218845 Ppp1cc Positive_regulation of Positive_regulation of Cysltr1 1 1 0.02 0.92 0.6
26 INT350859 Hist1h1t Regulation of Gene_expression of Kcnj5 1 1 0.02 0.37 0.59
27 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 1 0.10 3.53 0.58
28 INT199976 EGF Regulation of ITGB3BP 1 1 0.02 0.77 0.57
29 INT350861 Hist1h1t Positive_regulation of Gene_expression of Kcnj5 1 1 0.02 0.35 0.56
30 INT311766 INCENP Negative_regulation of Gene_expression of SLC1A3 1 1 0.04 0 0.55
31 INT323611 Il1 Regulation of Hmgb1 1 1 0.17 2.36 0.55
32 INT215101 Hmgb1 Positive_regulation of Localization of Il6 1 4 0.16 1.18 0.54
33 INT248997 Gabrg1 Positive_regulation of Clock 1 1 0.37 0 0.54
34 INT248995 Gabrg1 Regulation of Transcription of Clock 1 1 0.36 0 0.54
35 INT249016 Gabrg1 Positive_regulation of Transcription of Clock 1 1 0.37 0 0.54
36 INT253767 Binding of Hmgb1 and Tlr9 1 2 0.12 1.78 0.52
37 INT196809 Arpp21 Regulation of Ppp1cc 1 1 0.01 0 0.52
38 INT292075 FSCN1 Positive_regulation of Gene_expression of Csnk1a1 1 1 0.03 0.57 0.52
39 INT196826 Ppp1r1b Regulation of Ppp1cc 1 1 0.10 0 0.51
40 INT304576 Binding of Arntl and Clock 1 6 0.37 0.43 0.5
41 INT189688 PRKCA Regulation of Transcription of TERT 1 1 0.13 0.2 0.5
42 INT189696 PRKCA Negative_regulation of Negative_regulation of TEP1 1 1 0.02 0.15 0.5
43 INT189680 PRKCA Negative_regulation of TEP1 1 1 0.02 0.15 0.5
44 INT350860 Hist1h1t Positive_regulation of Kcnj5 1 1 0.02 0.54 0.5
45 INT189675 Negative_regulation of PRKCA Negative_regulation of TEP1 1 1 0.02 0.15 0.5
46 INT103535 Obfc1 Negative_regulation of Positive_regulation of Gad1 1 1 0.03 0.07 0.49
47 INT253770 Hmgb1 Positive_regulation of Localization of Apex1 1 1 0.08 0.71 0.49
48 INT132060 NBN Positive_regulation of Nos2 1 1 0.01 0.21 0.49
49 INT346325 Sirpa Regulation of Obfc1 1 1 0.00 0.41 0.48
50 INT231340 INCENP Regulation of Gene_expression of IL6 1 1 0.01 1.09 0.47
51 INT177794 BUB1B Positive_regulation of Gene_expression of ASNS 1 1 0.11 0.77 0.46
52 INT177781 BUB1B Positive_regulation of ATF4 1 1 0.07 0.76 0.46
53 INT177780 BUB1B Positive_regulation of ASNS 1 1 0.05 0.76 0.46
54 INT103536 Obfc1 Regulation of Gene_expression of Penk 1 1 0.00 0.08 0.46
55 INT177787 BUB1B Positive_regulation of MTHFD2 1 1 0.15 0.76 0.46
56 INT155086 CASP1 Negative_regulation of DAXX 1 1 0.21 1.26 0.45
57 INT167619 Protein_catabolism of Ppp2cb Positive_regulation of App 1 1 0.00 0.88 0.44
58 INT304577 Binding of Arntl and Clock Regulation of Gene_expression of Maoa 1 1 0.01 0.3 0.44
59 INT229507 Binding of Nefl and Ndel1 1 1 0.09 2.01 0.43
60 INT344104 Binding of Slc6a3 and Obfc1 1 1 0.00 0 0.43
61 INT249011 Gabrg1 Regulation of Clock 1 1 0.19 0 0.43
62 INT322396 Hist1h1t Positive_regulation of Akt1 1 1 0.01 0 0.42
63 INT40208 Binding of Eef1a1 and Hils1 1 1 0.01 0.22 0.42
64 INT322394 Hist1h1t Positive_regulation of Pik3cb 1 1 0.01 0 0.42
65 INT313455 Binding of Ppp2ca and Syp 1 1 0.45 0.68 0.4
66 INT196828 Prkaca Positive_regulation of Ppp2ca 1 1 0.20 0 0.4
67 INT196800 Trh Negative_regulation of Ppp1cc 1 1 0.01 0 0.39
68 INT196829 Ppp1r1b Negative_regulation of Phosphorylation of Ppp1cc 1 1 0.07 0 0.39
69 INT256321 INCENP Positive_regulation of Gene_expression of Vcam1 1 1 0.00 1.89 0.38
70 INT199974 ESR1 Negative_regulation of Gene_expression of ITGB3BP 1 1 0.05 0.47 0.38
71 INT266553 Ppp2r1a Positive_regulation of Fig4 1 1 0.00 0 0.38
72 INT344103 Positive_regulation of Drd1a Positive_regulation of Obfc1 1 1 0.00 0 0.38
73 INT28991 Tmpo Positive_regulation of Gene_expression of Pomc 1 1 0.34 0.82 0.37
74 INT249004 Helt Regulation of Clock 1 1 0.01 0.09 0.37
75 INT299788 INCENP Negative_regulation of Gene_expression of NPEPPS 1 1 0.00 0.86 0.37
76 INT324823 Tlr4 Positive_regulation of Gene_expression of Hmgb1 1 1 0.21 0.51 0.37
77 INT249015 Regulation of Helt Regulation of Clock 1 1 0.01 0.09 0.37
78 INT262760 Binding of TEP1 and CD163L1 1 1 0.00 1.65 0.37
79 INT324803 Hmgb1 Positive_regulation of Gene_expression of Bad 1 1 0.02 0.44 0.37
80 INT324818 Hmgb1 Positive_regulation of Gene_expression of Tlr4 1 1 0.21 0.51 0.37
81 INT324819 Hmgb1 Positive_regulation of Gene_expression of Maob 1 1 0.09 0.44 0.37
82 INT324827 Hmgb1 Positive_regulation of Bad 1 1 0.02 0.43 0.36
83 INT218843 Binding of Ppp1cc and Ppp1r9a 1 1 0.17 0.52 0.36
84 INT189687 INSRR Negative_regulation of Transcription of TERT 1 1 0.00 0.24 0.35
85 INT196820 Negative_regulation of Ppp1cc Positive_regulation of Akt1 1 1 0.00 0 0.34
86 INT280190 Cbs Regulation of Gene_expression of Hist1h1t 1 1 0.04 0.58 0.32
87 INT253762 Binding of Apex1 and Hmgb1 1 1 0.09 1.29 0.32
88 INT235869 Binding of Slc6a4 and Ppp2ca 1 1 0.04 0.21 0.31
89 INT218849 Negative_regulation of Ppp1cc Negative_regulation of Cysltr1 Positive_regulation of Ltp 1 1 0.01 0.42 0.31
90 INT235872 Phosphorylation of Ppp2ca Positive_regulation of Slc37a4 1 1 0.00 0.15 0.31
91 INT218831 Ppp1cc Regulation of Gria2 1 1 0.27 0.86 0.3
92 INT235886 Ppp2ca Positive_regulation of Slc37a4 1 1 0.00 0.15 0.3
93 INT56250 Binding of NBN and NCOR2 1 1 0.00 0 0.3
94 INT196825 Prkaca Positive_regulation of Phosphorylation of Ppp2ca 1 1 0.20 0 0.29
95 INT226375 INCENP Positive_regulation of Regulation of TH1L 1 1 0.01 0.57 0.29
96 INT196831 Positive_regulation of Prkaca Positive_regulation of Ppp2ca 1 1 0.20 0 0.29
97 INT196814 Negative_regulation of Prkaca Positive_regulation of Ppp2ca 1 1 0.17 0 0.29
98 INT226376 INCENP Negative_regulation of Gene_expression of TH1L 1 1 0.00 0.61 0.29
99 INT218847 Ppp1cc Positive_regulation of Regulation of Ltp 1 1 0.22 0.46 0.29
100 INT226383 IL22 Positive_regulation of Gene_expression of INCENP 1 1 0.00 0.85 0.28
101 INT199978 ESR1 Regulation of ITGB3BP 1 1 0.03 0.39 0.28
102 INT329528 Seh1l Positive_regulation of Gene_expression of Csf2 1 1 0.07 0.37 0.28
103 INT306267 Binding of INCENP and TP53 1 1 0.02 0.83 0.27
104 INT313446 Syp Regulation of Ppp2ca 1 1 0.58 0.62 0.26
105 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 1 0.01 1.34 0.26
106 INT126550 Agt Positive_regulation of Gene_expression of Nsfl1c 1 1 0.39 1.07 0.26
107 INT302468 INCENP Positive_regulation of Gene_expression of MMP9 1 1 0.01 0.72 0.26
108 INT323612 Negative_regulation of Tlr4 Positive_regulation of Hmgb1 1 1 0.23 0.2 0.25
109 INT323610 Tlr4 Positive_regulation of Hmgb1 1 1 0.25 0.2 0.25
110 INT302169 PTGER2 Positive_regulation of DYNC1LI1 1 1 0.02 1.51 0.25
111 INT253765 Apex1 Positive_regulation of Hmgb1 1 1 0.09 1.27 0.24
112 INT343914 Hmgb1 Positive_regulation of Gene_expression of IL12A 1 1 0.01 0.41 0.24
113 INT253771 Gopc Positive_regulation of Hmgb1 1 1 0.03 1.27 0.24
114 INT343906 Hmgb1 Positive_regulation of Gene_expression of Cd40 1 1 0.05 0.41 0.24
115 INT269561 TMPO Positive_regulation of RHOA 1 1 0.22 0 0.23
116 INT253773 TNF Positive_regulation of Hmgb1 1 1 0.09 1.21 0.23
117 INT252213 INCENP Regulation of Lgals3 1 1 0.00 1.91 0.23
118 INT183945 INCENP Positive_regulation of Localization of IL6 1 1 0.00 0.2 0.23
119 INT296372 Binding of IDUA and ACD 1 1 0.03 2.72 0.23
120 INT344833 Binding of Ager and Hmgb1 1 1 0.08 0.72 0.22
121 INT90280 Binding of Ppp1cc and Ppp2ca 2 1 0.34 0.22 0.22
122 INT331602 Binding of SSRP1 and Tlr4 1 1 0.03 0.9 0.21
123 INT309513 Binding of Xrcc6 and Htt 1 1 0.30 3.69 0.21
124 INT120716 Binding of AKT1 and TEP1 1 1 0.05 0.46 0.21
125 INT52355 Cfp Negative_regulation of Ndel1 1 1 0.34 0.16 0.21
126 INT159132 Klf9 Positive_regulation of Smc5 1 1 0.01 0.48 0.2
127 INT226384 INCENP Positive_regulation of IL19 1 1 0.00 0.58 0.2
128 INT132054 NBN Positive_regulation of NOS1 1 1 0.00 0.08 0.2
129 INT229513 Positive_regulation of Binding of Ndel1 and Gopc 1 1 0.09 0.2 0.2
130 INT258289 Hmgb1 Positive_regulation of Tlr2 1 4 0.48 3.61 0.19
131 INT324815 Binding of Hmgb1 and Caprin1 1 1 0.01 0.65 0.19
132 INT265048 INCENP Positive_regulation of Positive_regulation of Nfasc 1 1 0.00 0.69 0.19
133 INT324797 Binding of Cd24a and Hmgb1 1 1 0.19 0.66 0.19
134 INT323613 Il1 Regulation of Localization of Hmgb1 1 1 0.10 0.75 0.19
135 INT226372 INCENP Negative_regulation of Gene_expression of IL5 1 1 0.00 1.12 0.18
136 INT231866 INCENP Regulation of Positive_regulation of Racgap1 1 1 0.00 0.58 0.18
137 INT262359 Binding of DISC1 and NDEL1 1 1 0.04 0.56 0.18
138 INT269322 TMPO Positive_regulation of Positive_regulation of NOS1 1 1 0.03 0 0.18
139 INT247084 Binding of F7 and H1F0 1 1 0.00 0.38 0.17
140 INT215094 Il6 Positive_regulation of Hmgb1 1 1 0.18 1.84 0.17
141 INT163273 H2BFM Regulation of TRPA1 1 1 0.23 0.42 0.17
142 INT222443 INCENP Positive_regulation of Localization of Pomc 1 1 0.00 0.75 0.17
143 INT313449 Siglec1 Regulation of Ppp2ca 1 1 0.03 0.61 0.17
144 INT182326 LBR Positive_regulation of Gene_expression of Birc5 1 1 0.00 0.46 0.17
145 INT344832 Hmgb1 Positive_regulation of Gene_expression of Nos2 1 1 0.12 0.82 0.17
146 INT235883 Ppp2ca Regulation of Slc6a4 1 1 0.03 0 0.15
147 INT226367 INCENP Negative_regulation of SOCS1 1 1 0.01 0.47 0.15
148 INT269325 DYNC1I2 Positive_regulation of TMPO 1 1 0.01 0 0.15
149 INT235879 Regulation of Ppp2ca Regulation of Slc6a4 1 1 0.03 0 0.15
150 INT229514 Positive_regulation of Ndel1 Positive_regulation of Binding of Vim and Ndel1 1 1 0.34 0 0.14
151 INT343833 INCENP Positive_regulation of TLR4 1 1 0.01 0.92 0.14
152 INT343840 Protein_catabolism of INCENP Positive_regulation of TLR4 1 1 0.01 0.92 0.14
153 INT45371 IGF1 Regulation of Smc1b 1 1 0.08 0 0.14
154 INT343920 Binding of TLR4 and Hmgb1 1 1 0.39 0.97 0.13
155 INT324866 Hmgb1 Positive_regulation of Tlr4 1 1 0.16 1.29 0.13
156 INT343917 Binding of IRF6 and Hmgb1 1 1 0.05 0.98 0.13
157 INT226378 INCENP Positive_regulation of Transcription of SOCS1 1 1 0.01 0.41 0.13
158 INT269326 PRKCA Positive_regulation of Localization of TMPO 1 1 0.01 0 0.13
159 INT269336 PRKCA Regulation of Localization of TMPO 1 1 0.01 0.12 0.13
160 INT276037 Binding of Prkaca and Ppp1cc 1 1 0.08 0 0.12
161 INT276040 Binding of Camk2a and Ppp1cc 1 1 0.13 0 0.12
162 INT253761 Hmgb1 Positive_regulation of Gene_expression of Gopc 1 1 0.03 0.73 0.12
163 INT269332 Binding of NOS3 and TMPO 1 1 0.01 0 0.12
164 INT210161 INCENP Positive_regulation of TNFRSF8 1 1 0.02 0.93 0.12
165 INT227701 Tlx2 Positive_regulation of Regulation of SSRP1 1 1 0.00 0.69 0.12
166 INT308004 Rsph1 Positive_regulation of Mapk14 1 1 0.02 0.61 0.12
167 INT253772 Binding of THBD and Hmgb1 1 1 0.05 0.95 0.12
168 INT253775 Negative_regulation of Binding of THBD and Hmgb1 1 1 0.06 0.69 0.12
169 INT171383 Ppp1cc Positive_regulation of Positive_regulation of Mapk1 1 1 0.18 0 0.11
170 INT196827 Phosphorylation of Prkaca Positive_regulation of Ppp2ca 1 1 0.18 0 0.11
171 INT235385 INCENP Negative_regulation of Bche 1 1 0.01 0.19 0.11
172 INT171385 Ppp1cc Positive_regulation of Phosphorylation of Egfr 1 1 0.15 0 0.11
173 INT285948 IL17A Regulation of Gene_expression of TERT 1 1 0.00 0.58 0.11
174 INT281022 Clock Negative_regulation of Per1 1 1 0.26 0.09 0.11
175 INT196819 Prkaca Positive_regulation of Binding of Ppp2ca and 1 1 0.20 0 0.11
176 INT171387 Ppp1cc Positive_regulation of Phosphorylation of Src 1 1 0.07 0 0.11
177 INT171392 Ppp1cc Positive_regulation of Phosphorylation of Gpbar1 1 1 0.06 0 0.11
178 INT281023 Clock Negative_regulation of Per2 1 1 0.31 0.09 0.11
179 INT84867 Ptger1 Negative_regulation of SETD2 1 1 0.00 1.09 0.11
180 INT189702 CHKB Regulation of Gene_expression of TERT 1 1 0.06 0.55 0.1
181 INT269415 Prkaca Regulation of Localization of TMPO 1 1 0.00 0 0.1
182 INT229506 Negative_regulation of Binding of Ndel1 and Gopc 1 1 0.08 0.35 0.09
183 INT2194 HIST2H2BD Regulation of REN 1 1 0.00 0.07 0.09
184 INT222442 Tlr4 Positive_regulation of Gene_expression of INCENP 1 1 0.00 0.34 0.09
185 INT215095 Negative_regulation of Il6 Positive_regulation of Hmgb1 1 1 0.13 1.03 0.09
186 INT304460 Ass1 Positive_regulation of Xist 1 1 0.00 0 0.09
187 INT229504 Negative_regulation of Binding of Nefl and Ndel1 1 1 0.08 0.33 0.09
188 INT74742 OBFC1 Negative_regulation of Positive_regulation of Pdyn 1 1 0.00 0.45 0.09
189 INT313430 Syp Positive_regulation of Ppp2ca 1 1 0.66 0.08 0.09
190 INT74740 OBFC1 Negative_regulation of Positive_regulation of Penk 1 1 0.00 0.45 0.09
191 INT250730 Hmgb1 Positive_regulation of Localization of TNF 1 1 0.08 0.92 0.09
192 INT74741 Negative_regulation of OBFC1 Negative_regulation of Positive_regulation of Pdyn 1 1 0.00 0.45 0.09
193 INT276033 Binding of Ppp1cc and Ppp1r1b 1 1 0.06 0 0.09
194 INT346323 Binding of Gopc and Obfc1 1 1 0.01 0 0.08
195 INT269324 Regulation of TNIP3 Negative_regulation of TMPO 1 1 0.00 0 0.08
196 INT313447 Ppp2ca Regulation of Phosphorylation of Syp 1 1 0.43 0 0.08
197 INT173058 INCENP Positive_regulation of Gene_expression of VEGFA 1 1 0.03 1.48 0.08
198 INT169551 HIST1H1B Positive_regulation of LCS1 1 1 0.20 0.31 0.08
199 INT346695 Negative_regulation of SOD1 Positive_regulation of Negative_regulation of Hist3h2a 1 1 0.00 0.41 0.08
200 INT188007 NLRP3 Regulation of Binding of TP53BP1 and 1 1 0.28 0.62 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported for chromosome. They are ordered first by their pain relevance and then by number of times they were reported in chromosome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26
2 INT292049 Gene_expression of Csnk1a1 1 0.59 28.22 19.53
3 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32
4 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31
5 INT174838 Localization of INCENP 80 0.64 19.05 12.89
6 INT39553 Gene_expression of Hmgb1 50 0.75 51.18 12.21
7 INT39244 Gene_expression of TMPO 137 0.77 14.55 11.83
8 INT149818 Gene_expression of Clock 81 0.70 14.15 10.04
9 INT114363 Positive_regulation of Hmgb1 50 0.67 48.92 8.15
10 INT121496 Gene_expression of TERT 107 0.78 45.6 7.42
11 INT212758 Binding of Hmgb1 40 0.44 35.6 7.41
12 INT90275 Negative_regulation of Ppp1cc 29 0.58 1.91 7.11
13 INT39242 Negative_regulation of TMPO 29 0.58 5.15 7.04
14 INT159518 Gene_expression of Clock 4 0.35 2.34 6.91
15 INT173639 Positive_regulation of INCENP 40 0.14 20.97 6.7
16 INT8101 Binding of INCENP 42 0.31 16.2 6.68
17 INT147366 Gene_expression of Hist1h1t 15 0.44 9.84 6.67
18 INT292062 Negative_regulation of Csnk1a1 1 0.44 7.57 6.52
19 INT170385 Regulation of Clock 29 0.49 4.95 6.39
20 INT104673 Positive_regulation of Obfc1 10 0.41 4.26 5.61
21 INT190520 Negative_regulation of Hmgb1 24 0.53 20.08 5.6
22 INT121494 Transcription of TERT 64 0.69 10.03 5.55
23 INT292072 Positive_regulation of Gene_expression of Csnk1a1 1 0.53 9.76 5.39
24 INT83728 Localization of TMPO 42 0.46 0.46 5.06
25 INT116464 Negative_regulation of Birc5 53 0.59 45.4 4.91
26 INT292060 Positive_regulation of Csnk1a1 1 0.53 6.03 4.57
27 INT178751 Positive_regulation of TMPO 51 0.44 1.47 4.41
28 INT162249 Gene_expression of Hist1h2aa 8 0.12 6.46 4.35
29 INT196782 Positive_regulation of Ppp2ca 32 0.61 1.89 4.33
30 INT292057 Regulation of Csnk1a1 1 0.34 3.52 4.33
31 INT215071 Positive_regulation of Localization of Hmgb1 34 0.63 22.03 4.15
32 INT37615 Gene_expression of ESCO1 6 0.72 1.1 4.15
33 INT215085 Positive_regulation of Gene_expression of Hmgb1 17 0.63 16.81 4.13
34 INT182311 Positive_regulation of Birc5 26 0.67 25.32 4.08
35 INT90277 Negative_regulation of Ppp2ca 15 0.41 4.04 4.02
36 INT215074 Negative_regulation of Localization of Hmgb1 28 0.57 15.09 4
37 INT112541 Gene_expression of Hmgb1 2 0.78 4.75 3.8
38 INT196779 Phosphorylation of Ppp2ca 28 0.72 1.86 3.25
39 INT292056 Localization of Csnk1a1 1 0.57 3.99 3.17
40 INT172551 Negative_regulation of INCENP 38 0.07 20.83 3.14
41 INT103533 Negative_regulation of Obfc1 6 0.54 1.79 2.98
42 INT112539 Positive_regulation of Gene_expression of Hmgb1 2 0.70 3.55 2.95
43 INT172177 Protein_catabolism of INCENP 18 0.37 6.34 2.91
44 INT200833 Gene_expression of Ndel1 2 0.73 5.56 2.9
45 INT90276 Gene_expression of Ppp1cc 10 0.73 0.83 2.87
46 INT31450 Binding of HIST1H1B 20 0.37 10.21 2.84
47 INT103529 Regulation of Obfc1 11 0.22 1.61 2.84
48 INT120717 Positive_regulation of TEP1 50 0.63 27.94 2.81
49 INT116463 Negative_regulation of Gene_expression of Birc5 40 0.59 33.99 2.74
50 INT90273 Positive_regulation of Ppp1cc 10 0.41 0.82 2.71
51 INT351263 Binding of CLOCK 1 0.18 0.46 2.71
52 INT39243 Regulation of TMPO 20 0.61 5.66 2.67
53 INT77925 Negative_regulation of TEP1 21 0.53 15.23 2.62
54 INT98457 Phosphorylation of Ppp1cc 11 0.33 0.12 2.57
55 INT292070 Binding of Csnk1a1 1 0.28 3.18 2.5
56 INT222400 Negative_regulation of Localization of INCENP 4 0.02 1.82 2.46
57 INT133194 Negative_regulation of TERT 23 0.48 4.01 2.45
58 INT139295 Gene_expression of Obfc1 11 0.42 2.93 2.43
59 INT3578 Negative_regulation of TPR 7 0.42 4.18 2.41
60 INT91837 Negative_regulation of Ppp2r1a 4 0.48 0.95 2.41
61 INT26696 Gene_expression of Hils1 4 0.21 1.18 2.38
62 INT269402 Phosphorylation of TMPO 17 0.32 0.17 2.36
63 INT149507 Positive_regulation of Hist1h1t 4 0.26 2.71 2.33
64 INT182312 Positive_regulation of Gene_expression of Birc5 26 0.69 25.3 2.32
65 INT100935 Positive_regulation of Cenpi 1 0.56 0 2.32
66 INT182318 Regulation of Birc5 25 0.60 23.58 2.29
67 INT116880 Gene_expression of SYCP1 6 0.73 13.37 2.29
68 INT269372 Positive_regulation of Localization of TMPO 19 0.23 0.25 2.23
69 INT100805 Binding of Ppp1cc 7 0.47 1.77 2.23
70 INT173090 Regulation of INCENP 24 0.09 9.45 2.16
71 INT13368 Binding of Hils1 5 0.23 0.46 2.14
72 INT189770 Positive_regulation of Transcription of TERT 1 0.28 1.36 2.14
73 INT192198 Phosphorylation of Ppp2cb 3 0.43 0.22 2.12
74 INT293563 Negative_regulation of Gene_expression of ESCO1 2 0.33 0.17 2.1
75 INT90272 Gene_expression of Ppp2ca 18 0.68 4.69 2.08
76 INT162247 Positive_regulation of Hist1h2aa 2 0.09 2.6 2.03
77 INT229467 Binding of Ndel1 1 0.45 2.71 2
78 INT189766 Regulation of Transcription of TERT 1 0.25 3.48 1.99
79 INT106153 Gene_expression of HJURP 5 0.04 2.33 1.85
80 INT73866 Binding of Hist1h2aa 5 0.43 0.46 1.85
81 INT170387 Transcription of Clock 11 0.63 1.78 1.83
82 INT269406 Binding of TMPO 35 0.31 1.43 1.82
83 INT253755 Regulation of Hmgb1 7 0.55 6.23 1.8
84 INT181280 Regulation of Gene_expression of INCENP 5 0.07 4 1.78
85 INT280198 Regulation of Hist1h1t 2 0.21 1.28 1.69
86 INT63812 Gene_expression of H1FNT 14 0.06 8.41 1.67
87 INT185017 Gene_expression of TOP2B 7 0.75 4.84 1.67
88 INT167657 Localization of Hmgb1 3 0.75 3.48 1.67
89 INT322389 Phosphorylation of Hist1h1t 1 0.03 0 1.67
90 INT229463 Positive_regulation of Ndel1 1 0.66 1.87 1.64
91 INT86368 Gene_expression of TEP1 31 0.50 16.36 1.63
92 INT292052 Regulation of Gene_expression of Csnk1a1 1 0.47 2.5 1.62
93 INT147403 Regulation of Gene_expression of TERT 11 0.27 3.45 1.54
94 INT192197 Regulation of Phosphorylation of Ppp2cb 1 0.04 0.22 1.54
95 INT112540 Negative_regulation of Hmgb1 2 0.26 1.98 1.51
96 INT220783 Gene_expression of Tert 39 0.77 12.55 1.49
97 INT149815 Positive_regulation of Gene_expression of Clock 7 0.46 0.87 1.45
98 INT129712 Positive_regulation of Gene_expression of TERT 12 0.70 7.3 1.44
99 INT133193 Positive_regulation of TERT 16 0.50 6.43 1.38
100 INT248976 Positive_regulation of Clock 8 0.48 0.15 1.38
101 INT139296 Positive_regulation of Gene_expression of Obfc1 4 0.31 2.18 1.38
102 INT144805 Regulation of Negative_regulation of Ppp2ca 1 0.28 0.24 1.38
103 INT57190 Positive_regulation of Nbn 1 0.41 0.16 1.36
104 INT171975 Negative_regulation of Gene_expression of INCENP 8 0.05 5.24 1.35
105 INT147607 Binding of TERT 16 0.48 12.36 1.31
106 INT189736 Regulation of TERT 22 0.40 3.58 1.29
107 INT41698 Localization of Hils1 3 0.16 0.54 1.29
108 INT173877 Positive_regulation of Gene_expression of INCENP 14 0.08 7.83 1.28
109 INT38916 Positive_regulation of Tert 3 0.33 1.92 1.28
110 INT269381 Positive_regulation of Phosphorylation of TMPO 9 0.20 0 1.27
111 INT71926 Gene_expression of Smc1b 6 0.35 3.64 1.27
112 INT18947 Negative_regulation of Hils1 3 0.04 1.11 1.27
113 INT13659 Positive_regulation of Rsph1 2 0.22 1.02 1.25
114 INT100934 Regulation of Positive_regulation of Cenpi 1 0.37 0 1.24
115 INT300926 Gene_expression of OBFC1 15 0.65 6.97 1.22
116 INT269411 Positive_regulation of Gene_expression of TMPO 9 0.23 0.65 1.22
117 INT165691 Localization of Banf1 1 0.64 0.94 1.2
118 INT25726 Positive_regulation of TOP2B 4 0.67 4.1 1.19
119 INT23415 Regulation of Hils1 2 0.27 0.29 1.18
120 INT329510 Gene_expression of Seh1l 1 0.67 2.95 1.18
121 INT196785 Regulation of Ppp2ca 5 0.54 2.1 1.17
122 INT192807 Gene_expression of SSRP1 14 0.49 19.28 1.15
123 INT123242 Negative_regulation of Casc5 1 0.04 0.95 1.13
124 INT229466 Localization of Ndel1 1 0.76 1.32 1.1
125 INT163727 Positive_regulation of Gene_expression of Hist1h2aa 2 0.08 1.28 1.09
126 INT133195 Negative_regulation of Transcription of TERT 4 0.42 2.9 1.08
127 INT199979 Gene_expression of ITGB3BP 1 0.11 2.83 1.08
128 INT292071 Regulation of Negative_regulation of Csnk1a1 1 0.34 0.64 1.07
129 INT227501 Gene_expression of SMG6 1 0.05 0.9 1.07
130 INT215077 Negative_regulation of Positive_regulation of Hmgb1 3 0.42 5.09 1.05
131 INT131200 Gene_expression of TNKS 5 0.65 1.24 1.04
132 INT84777 Negative_regulation of H1f0 1 0.14 0 1.02
133 INT280196 Positive_regulation of Gene_expression of Hist1h1t 1 0.07 1.62 1.02
134 INT19849 Positive_regulation of Smc1b 8 0.50 4.09 1.01
135 INT70201 Negative_regulation of ESCO2 4 0.37 1.46 1.01
136 INT163726 Transcription of Hist1h2aa 1 0.03 0.54 0.99
137 INT123136 Positive_regulation of Gene_expression of Mki67ip 1 0.01 1.57 0.98
138 INT269384 Negative_regulation of Gene_expression of TMPO 10 0.23 0.47 0.97
139 INT182313 Regulation of Gene_expression of Birc5 18 0.60 15.34 0.96
140 INT215078 Negative_regulation of Gene_expression of Hmgb1 4 0.41 4.3 0.96
141 INT145159 Negative_regulation of Localization of Nsfl1c 1 0.08 0.43 0.95
142 INT292066 Negative_regulation of Gene_expression of Csnk1a1 1 0.32 2.01 0.95
143 INT183499 Gene_expression of Rsph1 5 0.11 4.74 0.94
144 INT90278 Localization of Ppp2ca 4 0.66 1.12 0.94
145 INT145158 Localization of Nsfl1c 1 0.15 0.43 0.93
146 INT107249 Negative_regulation of Negative_regulation of Cenpi 1 0.37 0 0.93
147 INT242656 Regulation of Hist1h2aa 3 0.04 2.68 0.92
148 INT351266 Regulation of Binding of CLOCK 1 0.21 0 0.92
149 INT71601 Positive_regulation of ACD 11 0.60 6.55 0.9
150 INT292067 Negative_regulation of Negative_regulation of Csnk1a1 1 0.32 0.56 0.9
151 INT292063 Positive_regulation of Positive_regulation of Csnk1a1 1 0.38 1.46 0.9
152 INT196754 Binding of Ppp2ca 5 0.37 0.42 0.89
153 INT76844 Positive_regulation of Rbm19 3 0.46 0.84 0.89
154 INT36494 Positive_regulation of Hils1 2 0.15 0.88 0.88
155 INT107251 Negative_regulation of Cenpi 1 0.37 0 0.87
156 INT167656 Negative_regulation of Gene_expression of Hmgb1 1 0.43 1.22 0.87
157 INT269413 Regulation of Localization of TMPO 7 0.18 0 0.86
158 INT189734 Negative_regulation of Gene_expression of TERT 8 0.24 1.84 0.85
159 INT175747 Regulation of CLOCK 4 0.21 0.06 0.84
160 INT222727 Positive_regulation of RANGAP1 2 0.41 1.62 0.83
161 INT107250 Binding of Cenpi 1 0.27 0 0.83
162 INT138956 Negative_regulation of Sycp1 1 0.43 0.68 0.82
163 INT137112 Regulation of HIST1H2AB 1 0.00 0.08 0.82
164 INT292048 Transcription of Csnk1a1 1 0.52 1.44 0.82
165 INT95190 Gene_expression of NDEL1 1 0.29 0 0.81
166 INT77612 Gene_expression of Tmpo 1 0.01 0.06 0.81
167 INT73868 Regulation of Binding of Hist1h2aa 1 0.55 0 0.81
168 INT269401 Regulation of Gene_expression of TMPO 8 0.18 2.89 0.78
169 INT190522 Regulation of Gene_expression of Hmgb1 1 0.39 1.47 0.77
170 INT73865 Negative_regulation of Binding of Hist1h2aa 1 0.52 0 0.77
171 INT196741 Positive_regulation of Negative_regulation of Ppp1cc 3 0.33 0.42 0.76
172 INT164813 Localization of Obfc1 3 0.15 0.36 0.76
173 INT156606 Positive_regulation of Acd 2 0.42 3.88 0.75
174 INT148658 Negative_regulation of Csnk1a1 2 0.08 0.99 0.75
175 INT68307 Negative_regulation of Ncapd2 3 0.42 1.2 0.74
176 INT169575 Regulation of H1FNT 3 0.07 3.41 0.74
177 INT248971 Binding of Clock 8 0.34 1.12 0.73
178 INT144880 Negative_regulation of DAXX 4 0.23 2.15 0.73
179 INT19848 Regulation of Smc1b 4 0.61 2.06 0.71
180 INT196753 Negative_regulation of Phosphorylation of Ppp2ca 3 0.37 0.52 0.7
181 INT94896 Regulation of TEP1 12 0.39 8.04 0.69
182 INT171747 Gene_expression of ACD 4 0.57 4.44 0.68
183 INT196742 Positive_regulation of Positive_regulation of Ppp2ca 4 0.44 0.05 0.68
184 INT88164 Regulation of Phosphorylation of Hmga1 1 0.07 0.31 0.68
185 INT192196 Regulation of Ppp2cb 1 0.04 0.11 0.68
186 INT40069 Negative_regulation of Binding of Hils1 1 0.03 0.09 0.67
187 INT105054 Negative_regulation of Ppp1cc 1 0.23 0 0.67
188 INT181282 Transcription of INCENP 10 0.11 1.21 0.66
189 INT26695 Positive_regulation of Binding of Hils1 2 0.11 0.2 0.66
190 INT346318 Positive_regulation of Obfc1 1 0.05 0.98 0.66
191 INT63064 Gene_expression of PRM1 7 0.50 2.66 0.65
192 INT14953 Binding of HIST3H3 1 0.24 0 0.65
193 INT42216 Positive_regulation of Hist2h2ab 1 0.01 0 0.65
194 INT126543 Gene_expression of Nsfl1c 2 0.75 1.69 0.64
195 INT196739 Regulation of Ppp1cc 5 0.19 0 0.63
196 INT280195 Regulation of Gene_expression of Hist1h1t 1 0.04 1.09 0.63
197 INT56251 Binding of NBN 4 0.38 3.16 0.62
198 INT296253 Negative_regulation of Gene_expression of Ppp2ca 3 0.41 1.71 0.62
199 INT42348 Regulation of Pes1 1 0.23 0 0.62
200 INT314577 Negative_regulation of Zw10 1 0.20 0 0.62
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