GOS:chromosome organization

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This page displays the top molecular interactions and top single events that were mentioned in the literature for chromosome organization. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for chromosome organization. They are ordered first by their pain relevance and then by number of times they were reported for chromosome organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Genes linked to chromosome organization Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 1 2 0.01 5.83 10.21
2 INT29240 Binding of POMC and YY1 1 5 0.40 0.17 4.06
3 INT123451 Binding of YY1 and Adra2a 1 1 0.37 0 2.98
4 INT39108 Binding of PDYN and YY1 1 2 0.50 0.44 2.14
5 INT62065 Binding of YY1 and Penk 1 3 0.14 0 1.69
6 INT30042 Binding of YY1 and Gnrhr 1 1 0.18 0 1.47
7 INT157540 Binding of SP1 and YY1 1 1 0.41 2.55 1.42
8 INT154114 PENK Positive_regulation of YY1 1 1 0.50 0.06 1.41
9 INT154113 POMC Positive_regulation of YY1 1 1 0.70 0.06 1.41
10 INT84886 APC Regulation of PPARD 1 1 0.51 1.57 1.26
11 INT59707 PSENEN Regulation of Negative_regulation of YY1 1 1 0.12 0.07 1.21
12 INT56882 Binding of YY1 and Ppbp 1 1 0.01 0 1.11
13 INT77982 Binding of YY1 and Oprm1 1 2 0.17 0.17 1.06
14 INT59518 YY1 Positive_regulation of SGCG 1 1 0.50 0.32 0.99
15 INT106248 Binding of CCR5 and YY1 1 1 0.54 0.19 0.98
16 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 1 0.06 0.99 0.96
17 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 1 0.30 1.76 0.94
18 INT73467 PTPLA Positive_regulation of Transcription of Myc 2 1 0.29 0.97 0.94
19 INT118204 ST14 Regulation of YY1 1 1 0.04 0 0.93
20 INT161915 Negative_regulation of Binding of POMC and YY1 1 1 0.33 0 0.88
21 INT30955 YY1 Negative_regulation of Negative_regulation of LH 1 1 0.23 0.47 0.87
22 INT116269 Binding of Myc and Mycbp2 2 1 0.19 0.5 0.87
23 INT330630 Binding of TP53 and Car1 1 1 0.23 1.56 0.86
24 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 1 0.36 0.51 0.83
25 INT97058 Cpz Regulation of Gene_expression of Trp53 1 1 0.27 0.57 0.83
26 INT322266 Binding of LIG4 and NOS3 1 1 0.02 2.35 0.82
27 INT151882 Binding of YY1 and DLL1 1 1 0.00 0 0.79
28 INT151883 Negative_regulation of Binding of YY1 and DLL1 1 1 0.00 0 0.79
29 INT166672 YY1 Regulation of Binding of UGT1A6 and 1 1 0.48 0 0.76
30 INT117412 RYBP Negative_regulation of LIG4 1 1 0.00 0.42 0.76
31 INT166674 YY1 Regulation of Binding of PRKCA and 1 1 0.38 0 0.75
32 INT195778 Binding of APC and PROCR 1 7 0.19 3.78 0.73
33 INT7049 Binding of YY1 and Oprd1 1 1 0.01 0 0.73
34 INT157541 Binding of YY1 and Regulation of Gene_expression of OPRM1 1 1 0.31 1.21 0.72
35 INT166671 YY1 Regulation of Positive_regulation of UGT1A6 1 1 0.48 0 0.7
36 INT133942 Binding of YY1 and ARFGEF1 1 1 0.05 0 0.69
37 INT133936 Binding of DNM2 and YY1 1 1 0.29 0 0.69
38 INT74599 YY1 Negative_regulation of ADCY1 1 2 0.36 0.31 0.67
39 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 1 0.52 2.45 0.67
40 INT314560 RYBP Positive_regulation of Gene_expression of MYC 1 1 0.02 0.06 0.67
41 INT114947 YY1 Positive_regulation of Gene_expression of RXRA 1 1 0.33 0.25 0.65
42 INT114950 YY1 Positive_regulation of Positive_regulation of PPARA 1 1 0.52 0.25 0.64
43 INT34005 YY1 Regulation of KNG1 1 1 0.04 0.38 0.63
44 INT135498 Binding of YY1 and MRGPRX4 1 1 0.00 0.2 0.62
45 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 1 0.27 0.83 0.61
46 INT120348 Negative_regulation of Binding of DES and MYC 1 1 0.06 0.18 0.58
47 INT74656 YY1 Positive_regulation of Localization of IL2 1 1 0.07 0.09 0.58
48 INT120350 Binding of DES and MYC 1 1 0.05 0.17 0.58
49 INT120347 Binding of KNG1 and MYC 1 1 0.21 0.17 0.58
50 INT142868 YY1 Positive_regulation of Oprd1 1 1 0.01 0.1 0.55
51 INT57546 Binding of YY1 and GNPTAB 1 1 0.00 0 0.53
52 INT110474 YY1 Positive_regulation of Positive_regulation of EDN1 1 1 0.56 0.15 0.53
53 INT254200 Mif Regulation of Trp53 1 1 0.02 0.96 0.52
54 INT135500 Positive_regulation of YY1 Positive_regulation of MRGPRX4 1 1 0.01 0.06 0.52
55 INT135501 MRGPRX4 Positive_regulation of YY1 1 1 0.00 0.06 0.52
56 INT135497 YY1 Positive_regulation of MRGPRX4 1 1 0.01 0.06 0.52
57 INT135503 MRGPRX4 Regulation of YY1 1 1 0.01 0.05 0.5
58 INT182150 Binding of APC and DCPS 1 1 0.02 1.14 0.48
59 INT34006 Binding of ITPR3 and YY1 1 1 0.22 0.33 0.48
60 INT58578 Binding of RPA1 and TACR1 1 1 0.01 0 0.48
61 INT114297 Apc Negative_regulation of Gene_expression of Fcer2a 2 1 0.03 0.96 0.48
62 INT168130 Mir190 Positive_regulation of Phosphorylation of Yy1 1 1 0.54 0 0.45
63 INT128521 Binding of YY1 and IGKV2-26 1 1 0.12 0 0.45
64 INT168131 Phosphorylation of Yy1 Positive_regulation of Gene_expression of Mir190 1 1 0.32 0 0.45
65 INT168129 Binding of Yy1 and Positive_regulation of Transcription of Tln2 1 1 0.02 0 0.44
66 INT8356 Binding of YY1 and Smpd1 1 1 0.32 0 0.43
67 INT168132 Binding of Yy1 and Tln2 1 1 0.01 0 0.43
68 INT302829 Mapkapk5 Positive_regulation of Trp53 1 1 0.07 0.81 0.43
69 INT168134 Phosphorylation of Yy1 Negative_regulation of Binding of Yy1 and Tln2 1 1 0.02 0 0.43
70 INT62066 Binding of YY1 and Pdyn 1 1 0.00 0 0.42
71 INT84885 APC Regulation of APC Regulation of PPARD 1 1 0.18 0.55 0.41
72 INT84887 APC Negative_regulation of Gene_expression of PPARD 1 1 0.36 0.55 0.37
73 INT239540 Binding of CXCR2 and MYC 1 1 0.15 0.09 0.33
74 INT91814 Binding of TNF and TP53 1 1 0.14 2.2 0.32
75 INT195665 APC Negative_regulation of F8 1 1 0.04 1.53 0.32
76 INT242164 Wnt2 Positive_regulation of Localization of Apc 2 1 0.13 1.53 0.32
77 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 1 0.28 0.41 0.31
78 INT166396 IFI27 Regulation of Gene_expression of TP53 1 1 0.19 0.41 0.31
79 INT195664 APC Negative_regulation of F5 1 1 0.08 1.51 0.31
80 INT63122 Binding of APC and Man2a2 1 1 0.01 0.15 0.3
81 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 1 0.01 1.23 0.3
82 INT333918 HDAC1 Regulation of Trp53 1 1 0.03 1.24 0.3
83 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 1 0.40 0.86 0.3
84 INT239537 CXCR2 Regulation of MYC 1 1 0.15 0.05 0.29
85 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 1 0.05 0.75 0.28
86 INT130107 YY1 Positive_regulation of MAPK1 1 1 0.45 0 0.28
87 INT130106 Regulation of YY1 Positive_regulation of MAPK1 1 1 0.41 0 0.28
88 INT289954 Binding of APC and CD28 1 1 0.03 0.38 0.28
89 INT286042 Binding of Tp53 and Wwox 1 1 0.04 2.05 0.28
90 INT216127 EGR1 Regulation of Transcription of TP53 1 1 0.06 0.21 0.28
91 INT302837 Binding of TNFRSF10D and Trp53 1 1 0.01 0.98 0.28
92 INT306267 Binding of INCENP and TP53 1 1 0.02 0.83 0.27
93 INT350813 Binding of Apc and Crp 2 1 0.18 1.12 0.27
94 INT216128 EGR1 Regulation of TP53 1 1 0.11 0.21 0.27
95 INT352931 Prkaca Regulation of TP53 1 1 0.13 1.01 0.26
96 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 1 0.13 1.02 0.26
97 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 1 0.01 1.34 0.26
98 INT172975 Trp53 Positive_regulation of Cdkn1a 1 1 0.03 1.35 0.26
99 INT352893 PTGDS Regulation of TP53 1 1 0.16 1.02 0.26
100 INT125516 TP53 Regulation of GDF15 1 1 0.10 0.47 0.26
101 INT337086 Mif Negative_regulation of Localization of Trp53 1 1 0.16 1.64 0.25
102 INT327300 Binding of Hnrnpd and Myc 2 1 0.12 1.02 0.25
103 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 1 0.16 1.64 0.25
104 INT235976 Binding of APC and Trav6-3 1 2 0.01 2.62 0.24
105 INT235974 Negative_regulation of Binding of APC and Trav6-3 1 1 0.00 1.15 0.24
106 INT156879 Gene_expression of TP53 Negative_regulation of Positive_regulation of PDF 1 1 0.45 0.9 0.24
107 INT181900 TP53 Negative_regulation of Gene_expression of NOS1 1 1 0.03 0.94 0.24
108 INT235972 Negative_regulation of Binding of APC and Bcr 1 1 0.01 1.15 0.24
109 INT235973 Binding of APC and Bcr 1 1 0.01 1.14 0.24
110 INT156881 TP53 Positive_regulation of Positive_regulation of PDF 1 1 0.49 0.89 0.24
111 INT109408 Negative_regulation of APC Negative_regulation of Positive_regulation of RASGRP1 1 1 0.06 0.73 0.23
112 INT229177 IFRD1 Regulation of TP53 1 1 0.13 0.68 0.23
113 INT250783 APC Negative_regulation of SERPINE1 1 1 0.06 0.86 0.23
114 INT151884 Binding of PRLR and YY1 1 1 0.01 0 0.23
115 INT250782 APC Negative_regulation of F2 1 1 0.00 0.86 0.23
116 INT61346 Positive_regulation of YY1 Positive_regulation of Localization of SST 1 1 0.54 0 0.22
117 INT316111 APC Negative_regulation of SAE1 1 1 0.04 1.21 0.22
118 INT226902 Padi3 Regulation of Trp53 1 1 0.06 0.69 0.22
119 INT195663 APC Negative_regulation of Gene_expression of IL6 1 1 0.16 1.18 0.22
120 INT229178 TP53 Regulation of ICAM1 1 1 0.07 0.9 0.21
121 INT64382 Positive_regulation of Binding of YY1 and Tyr 1 1 0.11 0 0.21
122 INT322017 RPA1 Positive_regulation of IL1B 1 1 0.00 0 0.21
123 INT156882 Binding of TP53 and PDF 1 1 0.39 0.77 0.21
124 INT64383 Binding of YY1 and Tyr 1 1 0.09 0 0.21
125 INT156880 TP53 Positive_regulation of Gene_expression of PDF 1 1 0.49 0.75 0.21
126 INT316110 Binding of APC and SAE1 1 1 0.03 1.16 0.2
127 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 1 0.33 0.93 0.2
128 INT79206 Binding of MGP and YY1 1 1 0.34 0 0.19
129 INT91862 RPA1 Negative_regulation of Transcription of ATG9B 1 1 0.03 0.46 0.19
130 INT193787 Positive_regulation of CXCR4 Positive_regulation of Positive_regulation of TP53 1 1 0.03 0.71 0.19
131 INT142853 Binding of TP53 and WISP2 1 1 0.33 1.43 0.19
132 INT58579 Binding of INSRR and RPA1 1 1 0.00 0 0.18
133 INT74600 Negative_regulation of YY1 Negative_regulation of ADCY1 1 1 0.36 0.25 0.17
134 INT334106 APC Negative_regulation of NFKB1 1 1 0.25 1.37 0.17
135 INT102804 NFKB1 Regulation of TP53 1 1 0.35 0.77 0.17
136 INT334108 APC Negative_regulation of TNF 1 1 0.13 1.36 0.17
137 INT102803 NFKB1 Regulation of Gene_expression of TP53 1 1 0.35 0.77 0.17
138 INT91812 Binding of FASLG and TP53 1 1 0.04 1.1 0.16
139 INT91811 Binding of FAS and TP53 1 1 0.21 1.1 0.16
140 INT116268 Binding of Myc and Acsl1 2 1 0.08 0.19 0.16
141 INT266377 Binding of S100a11 and Trp53 1 1 0.02 0.89 0.15
142 INT311666 Binding of BCL2 and TP53 1 1 0.19 1.26 0.14
143 INT239557 Binding of MYC and Hopx 1 1 0.14 0 0.14
144 INT299763 Binding of APC and CTLA4 Positive_regulation of Ido1 1 1 0.11 0.31 0.14
145 INT252902 PTTG1 Regulation of MMP2 1 1 0.01 1.5 0.14
146 INT253009 Igf1 Regulation of PTTG1 1 1 0.03 0.44 0.13
147 INT144589 Binding of YY1 and Oprl1 1 1 0.04 0.73 0.13
148 INT103557 Binding of ERCC2 and TP53 1 1 0.40 1 0.13
149 INT289956 Binding of APC and ICAM1 1 1 0.04 0.5 0.13
150 INT201722 Myc Regulation of Gene_expression of Ccnd1 2 1 0.03 0.79 0.13
151 INT132148 LTF Positive_regulation of TP53 1 1 0.44 0.56 0.13
152 INT320261 Binding of Myc and Ntrk2 2 1 0.01 0.36 0.13
153 INT242163 Wnt2 Positive_regulation of Regulation of Apc 2 1 0.13 0.71 0.13
154 INT201791 JUP Regulation of Gene_expression of Myc 2 1 0.49 0.8 0.13
155 INT253015 Egf Regulation of PTTG1 1 1 0.02 0.44 0.13
156 INT252901 PTTG1 Regulation of Gene_expression of TSC1 1 1 0.00 1.61 0.13
157 INT103561 Binding of TP53 and Mc1r 1 1 0.03 1 0.13
158 INT184603 APC Negative_regulation of Gene_expression of TNF 1 1 0.09 0.97 0.13
159 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 1 0.08 1.25 0.13
160 INT173200 PPA1 Positive_regulation of Myc 2 1 0.08 0.5 0.12
161 INT316190 Apc Negative_regulation of Positive_regulation of Mapk1 2 1 0.33 0.66 0.12
162 INT184608 APC Regulation of Gene_expression of Nppa 1 1 0.06 1.11 0.12
163 INT299754 Binding of APC and CTLA4 1 2 0.08 0.97 0.11
164 INT83370 Binding of HRAS and TP53 1 1 0.30 0.59 0.11
165 INT276064 Src Regulation of Positive_regulation of Rpa1 1 1 0.02 0.18 0.11
166 INT266386 Binding of S100a1 and Trp53 1 1 0.03 0.64 0.1
167 INT69909 Binding of MYC and PURA 1 1 0.24 0 0.1
168 INT193782 Binding of TP53 and SDF2L1 1 1 0.00 0.67 0.1
169 INT276041 Positive_regulation of Gabbr2 Negative_regulation of Positive_regulation of Rpa1 1 1 0.01 0 0.1
170 INT262522 Binding of Trp53 and Foxo4 1 1 0.05 0.7 0.1
171 INT310743 TP53 Regulation of BAX 1 1 0.09 1.11 0.1
172 INT262255 Binding of APC and F2R 1 1 0.05 3 0.1
173 INT276039 Positive_regulation of Car2 Positive_regulation of Positive_regulation of Rpa1 1 1 0.04 0 0.09
174 INT326126 Binding of S100A1 and TP53 1 1 0.04 1.34 0.09
175 INT352611 Trp53 Negative_regulation of Localization of Gli1 1 1 0.23 1.2 0.09
176 INT302168 YWHAQ Regulation of TP53 1 1 0.01 0.41 0.09
177 INT265466 CSPG4 Regulation of Phosphorylation of TP53 1 1 0.09 0.15 0.09
178 INT221653 Binding of Myc and Gopc 1 2 0.12 0.51 0.08
179 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 1 0.10 0.96 0.08
180 INT270203 Binding of CD28 and Apc 2 1 0.04 0.58 0.08
181 INT189957 Binding of LDHA and Pttg1 1 1 0.05 0.35 0.08
182 INT270197 Binding of Apc and Cd86 2 1 0.02 0.58 0.08
183 INT266394 Binding of S100a4 and Trp53 1 1 0.03 0.59 0.08
184 INT270198 Binding of Apc and Cd80 2 1 0.02 0.58 0.08
185 INT266390 Binding of S100a6 and Trp53 1 1 0.04 0.51 0.07
186 INT339897 Binding of Bnc1 and Shc4 1 1 0.05 0.69 0.07
187 INT245296 Trp53 Regulation of Gadd45a 1 1 0.05 0.43 0.07
188 INT266398 Binding of S100b and Trp53 1 1 0.06 0.92 0.07
189 INT195556 Smc2 Regulation of Gene_expression of Grm3 1 1 0.01 0 0.06
190 INT302143 TP53 Regulation of Positive_regulation of CASP3 1 1 0.01 0.69 0.06
191 INT338902 Binding of MAX and MYC 1 1 0.02 0.23 0.06
192 INT195550 Smc2 Regulation of Gene_expression of Grm2 1 1 0.02 0 0.06
193 INT302155 TP53 Regulation of Positive_regulation of CASP9 1 1 0.02 0.7 0.06
194 INT204074 Tp53 Positive_regulation of Cdkn1b 1 1 0.00 0.59 0.06
195 INT140291 ROS1 Positive_regulation of TP53 1 1 0.52 1.27 0.06
196 INT276049 Pde1b Regulation of Positive_regulation of Rpa1 1 1 0.04 0 0.06
197 INT265459 Phosphorylation of TP53 Positive_regulation of Localization of CASP9 1 1 0.17 1.16 0.05
198 INT345197 Gpr87 Regulation of Gpr87 Regulation of Trp53 1 1 0.00 0.42 0.05
199 INT176095 Binding of Apc and EC 2 1 0.04 0.51 0.05
200 INT352618 Tpt1 Regulation of Trp53 1 1 0.06 0.54 0.05

Single Events

The table below shows the top 100 pain related interactions that have been reported for chromosome organization. They are ordered first by their pain relevance and then by number of times they were reported in chromosome organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6437 Binding of YY1 154 0.47 26.3 90.46
2 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16
3 INT789 Positive_regulation of YY1 69 0.67 14.07 47.06
4 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
5 INT6717 Negative_regulation of YY1 45 0.57 15.35 27.8
6 INT3359 Regulation of YY1 32 0.60 8.19 19.2
7 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
8 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
9 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
10 INT20420 Gene_expression of MYC 99 0.75 49.32 14.36
11 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
12 INT18647 Localization of YY1 16 0.78 4.04 9.77
13 INT57057 Gene_expression of APC 131 0.78 122.24 8.7
14 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
15 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
16 INT16631 Negative_regulation of APC 46 0.57 30.53 7.11
17 INT33419 Positive_regulation of Gene_expression of YY1 10 0.67 4.15 7.08
18 INT25647 Negative_regulation of Binding of YY1 10 0.57 1.47 6.77
19 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
20 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02
21 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
22 INT17892 Gene_expression of Myc 57 0.75 36.37 5.82
23 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22
24 INT60585 Regulation of TP53 59 0.59 54.55 5.21
25 INT80038 Positive_regulation of Gene_expression of MYC 24 0.67 13.93 5.17
26 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08
27 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
28 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
29 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
30 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91
31 INT73750 Regulation of Gene_expression of YY1 7 0.44 0.28 3.91
32 INT63121 Binding of APC 29 0.41 23.02 3.8
33 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
34 INT53891 Positive_regulation of Positive_regulation of YY1 5 0.49 0.24 3.65
35 INT29356 Positive_regulation of Binding of YY1 8 0.67 0.22 3.49
36 INT20419 Negative_regulation of Gene_expression of MYC 19 0.57 9.7 3.29
37 INT107962 Gene_expression of Pttg1 34 0.53 34.05 3.11
38 INT138319 Positive_regulation of Rpa1 3 0.07 2.75 3.07
39 INT53889 Negative_regulation of Positive_regulation of YY1 6 0.41 0.57 3.05
40 INT8103 Binding of TP53 46 0.44 40.2 2.96
41 INT73263 Negative_regulation of MYC 20 0.57 12.86 2.95
42 INT53890 Transcription of YY1 8 0.67 1.53 2.88
43 INT36886 Transcription of Myc 6 0.69 3.16 2.86
44 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
45 INT73460 Positive_regulation of Gene_expression of Myc 26 0.67 20.44 2.61
46 INT168116 Phosphorylation of Yy1 1 0.71 0 2.57
47 INT59709 Negative_regulation of Negative_regulation of YY1 3 0.57 0.07 2.55
48 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
49 INT55952 Transcription of TP53 16 0.61 12.14 2.36
50 INT82798 Regulation of MYC 19 0.60 12.06 2.31
51 INT107685 Phosphorylation of MYC 3 0.80 2.52 2.28
52 INT117415 Negative_regulation of LIG4 4 0.04 1.59 2.17
53 INT73476 Transcription of MYC 18 0.69 12.14 2.13
54 INT16656 Negative_regulation of Gene_expression of YY1 8 0.57 2.62 2.12
55 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
56 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
57 INT20421 Positive_regulation of MYC 19 0.67 10.43 1.9
58 INT65855 Localization of TP53 18 0.76 17.08 1.89
59 INT239093 Gene_expression of PTTG1 84 0.65 83.94 1.87
60 INT27168 Positive_regulation of BLM 1 0.70 0 1.84
61 INT155110 Negative_regulation of Phosphorylation of MYC 1 0.57 1.61 1.83
62 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
63 INT79802 Phosphorylation of YY1 2 0.80 0.07 1.7
64 INT3818 Regulation of Apc 13 0.39 12.52 1.68
65 INT73475 Positive_regulation of Transcription of MYC 7 0.67 5.46 1.66
66 INT27167 Negative_regulation of BLM 1 0.43 0.32 1.58
67 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
68 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
69 INT58581 Binding of RPA1 8 0.44 1.68 1.44
70 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
71 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
72 INT189948 Gene_expression of Pttg1 106 0.76 104.68 1.41
73 INT172953 Binding of Trp53 33 0.37 20.76 1.41
74 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
75 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
76 INT220177 Binding of Apc 21 0.37 15.34 1.37
77 INT145221 Binding of Tp53 10 0.37 8.59 1.37
78 INT121307 Gene_expression of Ercc1 4 0.73 12.69 1.37
79 INT172452 Gene_expression of Myc 121 0.78 69.56 1.36
80 INT116265 Binding of Myc 9 0.36 4.28 1.36
81 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3
82 INT20418 Regulation of Gene_expression of MYC 6 0.60 4.4 1.29
83 INT59708 Regulation of Negative_regulation of YY1 1 0.44 0.07 1.21
84 INT174156 Localization of Trp53 16 0.72 13.52 1.18
85 INT116436 Negative_regulation of Phosphorylation of TP53 2 0.40 0.94 1.16
86 INT102073 Regulation of Gene_expression of APC 5 0.45 6.09 1.15
87 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
88 INT91872 Gene_expression of RPA1 9 0.77 5.28 1.12
89 INT71848 Positive_regulation of Transcription of Myc 1 0.67 0.16 1.11
90 INT102074 Positive_regulation of Gene_expression of APC 20 0.50 13.66 1.1
91 INT107961 Positive_regulation of Gene_expression of Pttg1 2 0.38 11.69 1.09
92 INT202264 Positive_regulation of Pttg1 8 0.45 8.03 1.04
93 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
94 INT87684 Positive_regulation of Blm 2 0.60 1.65 0.98
95 INT102070 Regulation of Gene_expression of Myc 4 0.60 2.68 0.96
96 INT167702 Negative_regulation of Rpa1 3 0.06 1.16 0.96
97 INT17894 Regulation of Myc 10 0.60 5.65 0.93
98 INT108012 Regulation of Localization of YY1 1 0.26 0 0.91
99 INT82795 Binding of MYC 16 0.47 6.1 0.9
100 INT168123 Positive_regulation of Phosphorylation of Yy1 1 0.60 0 0.89
101 INT242134 Localization of Apc 8 0.74 4.83 0.88
102 INT168114 Binding of Yy1 1 0.32 0 0.85
103 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
104 INT147433 Gene_expression of BRCA2 7 0.62 7.02 0.79
105 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75
106 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
107 INT252975 Positive_regulation of Gene_expression of PTTG1 36 0.28 31.96 0.74
108 INT92222 Positive_regulation of Phosphorylation of YY1 1 0.49 0 0.74
109 INT162470 Negative_regulation of Protein_catabolism of TP53 1 0.32 1.24 0.74
110 INT57062 Regulation of APC 24 0.58 14.3 0.7
111 INT276010 Regulation of Positive_regulation of Rpa1 1 0.06 0.72 0.7
112 INT80674 Negative_regulation of Gene_expression of APC 16 0.59 18.14 0.69
113 INT268557 Regulation of Regulation of MYC 1 0.44 0.86 0.69
114 INT156404 Negative_regulation of Pttg1 2 0.23 4.06 0.62
115 INT167701 Phosphorylation of Rpa1 1 0.01 0.16 0.61
116 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6
117 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
118 INT107686 Positive_regulation of Negative_regulation of MYC 2 0.49 1.59 0.6
119 INT69546 Protein_catabolism of YY1 2 0.64 0.35 0.58
120 INT333877 Protein_catabolism of LIG4 2 0.03 2.03 0.57
121 INT178222 Gene_expression of Yy1 5 0.57 2.06 0.56
122 INT71130 Regulation of Positive_regulation of YY1 1 0.44 0 0.55
123 INT16657 Positive_regulation of Negative_regulation of YY1 1 0.49 0.42 0.55
124 INT72869 Regulation of Negative_regulation of APC 2 0.36 1.7 0.54
125 INT202259 Transcription of Pttg1 1 0.34 4.13 0.53
126 INT96263 Positive_regulation of Transcription of YY1 2 0.49 0.75 0.51
127 INT286035 Negative_regulation of Gene_expression of Tp53 5 0.32 6.2 0.49
128 INT126036 Gene_expression of Smc2 4 0.65 0.28 0.47
129 INT151720 Negative_regulation of Positive_regulation of Apc 3 0.37 2.15 0.46
130 INT13381 Regulation of Binding of YY1 2 0.44 0 0.46
131 INT150433 Negative_regulation of Yy1 3 0.20 0.56 0.45
132 INT338935 Binding of Itpa 1 0.08 0.93 0.45
133 INT168126 Regulation of Phosphorylation of Yy1 1 0.39 0 0.43
134 INT152151 Regulation of Gene_expression of Apc 4 0.44 3.87 0.42
135 INT121310 Positive_regulation of Ercc1 2 0.45 1.78 0.42
136 INT168119 Negative_regulation of Binding of Yy1 1 0.37 0 0.42
137 INT168122 Negative_regulation of Phosphorylation of Yy1 1 0.37 0 0.42
138 INT90354 Negative_regulation of Myc 6 0.57 4.24 0.4
139 INT139976 Regulation of Tp53 7 0.44 6.49 0.39
140 INT189946 Positive_regulation of Gene_expression of Pttg1 14 0.68 23.72 0.38
141 INT219001 Gene_expression of ERCC1 12 0.54 3.77 0.38
142 INT58580 Positive_regulation of Binding of RPA1 2 0.43 0 0.38
143 INT275992 Positive_regulation of Positive_regulation of Rpa1 1 0.05 0.31 0.36
144 INT145220 Negative_regulation of Binding of Tp53 1 0.20 0.75 0.36
145 INT252989 Localization of PTTG1 1 0.32 1.49 0.36
146 INT220170 Regulation of Positive_regulation of Apc 1 0.10 0.46 0.35
147 INT150432 Positive_regulation of Regulation of Yy1 1 0.19 0.39 0.35
148 INT150435 Regulation of Yy1 1 0.11 0.39 0.35
149 INT202268 Regulation of Gene_expression of Pttg1 3 0.33 3.1 0.34
150 INT118243 Transcription of APC 4 0.45 3.33 0.33
151 INT184605 Positive_regulation of Transcription of APC 2 0.19 2.39 0.33
152 INT225667 Transcription of Apc 3 0.52 3.73 0.32
153 INT195672 Localization of APC 7 0.74 3.76 0.3
154 INT93355 Negative_regulation of Negative_regulation of Trp53 2 0.41 0.92 0.3
155 INT179089 Protein_catabolism of Trp53 8 0.90 6.52 0.29
156 INT342855 Gene_expression of Ercc1 1 0.22 1.82 0.29
157 INT202269 Regulation of Pttg1 3 0.33 2.47 0.27
158 INT189335 Gene_expression of Rpa1 2 0.07 0.07 0.27
159 INT166960 Positive_regulation of Negative_regulation of TP53 2 0.25 1.65 0.26
160 INT187547 Localization of Myc 1 0.68 0.92 0.26
161 INT187548 Regulation of Transcription of Myc 1 0.44 0.68 0.26
162 INT172445 Positive_regulation of Gene_expression of Myc 58 0.70 39.62 0.25
163 INT173223 Negative_regulation of BRCA2 7 0.54 6.79 0.25
164 INT189953 Regulation of PTTG1 2 0.18 6.45 0.25
165 INT314729 Regulation of Localization of TP53 1 0.30 2.5 0.25
166 INT179088 Positive_regulation of Regulation of Trp53 3 0.38 3.23 0.23
167 INT156886 Positive_regulation of Localization of TP53 1 0.48 0.87 0.23
168 INT150434 Regulation of Negative_regulation of Yy1 1 0.13 0.15 0.23
169 INT102071 Negative_regulation of Gene_expression of Myc 8 0.57 3.5 0.22
170 INT225666 Regulation of Transcription of Apc 1 0.29 0.33 0.22
171 INT121311 Positive_regulation of Gene_expression of Ercc1 3 0.62 1.23 0.21
172 INT13867 Negative_regulation of Regulation of YY1 1 0.41 0 0.21
173 INT275996 Negative_regulation of Positive_regulation of Rpa1 1 0.05 0.44 0.2
174 INT63067 Localization of MYC 13 0.78 6.93 0.19
175 INT19359 Binding of BRCA2 5 0.47 2.63 0.19
176 INT173166 Negative_regulation of Binding of APC 3 0.40 3.01 0.19
177 INT89690 Binding of Brca2 2 0.37 1.8 0.18
178 INT252977 Positive_regulation of PTTG1 1 0.28 8.39 0.18
179 INT169875 Negative_regulation of Ercc1 3 0.43 3.07 0.17
180 INT57065 Negative_regulation of Positive_regulation of APC 3 0.22 2.43 0.17
181 INT300284 Regulation of Phosphorylation of Tp53 1 0.16 1.51 0.17
182 INT228603 Positive_regulation of Positive_regulation of Apc 1 0.24 0.24 0.17
183 INT337078 Negative_regulation of Localization of Trp53 1 0.20 1.3 0.17
184 INT189945 Localization of Pttg1 3 0.73 3.02 0.16
185 INT202260 Regulation of Transcription of Pttg1 1 0.21 1.13 0.16
186 INT91870 Negative_regulation of Gene_expression of RPA1 1 0.58 0.4 0.16
187 INT179086 Positive_regulation of Negative_regulation of Trp53 5 0.50 4.78 0.15
188 INT125081 Positive_regulation of Binding of TP53 2 0.46 1.2 0.15
189 INT207805 Negative_regulation of Phosphorylation of Trp53 2 0.18 0.98 0.15
190 INT91871 Transcription of RPA1 1 0.69 0.38 0.15
191 INT286749 Regulation of Localization of Trp53 1 0.06 1.39 0.15
192 INT339892 Positive_regulation of Bnc1 1 0.17 3.82 0.15
193 INT91866 Positive_regulation of Gene_expression of RPA1 1 0.69 0.38 0.15
194 INT265097 Positive_regulation of Pot1 1 0.22 0 0.14
195 INT180196 Binding of DCLRE1C 1 0.08 0.49 0.14
196 INT250790 Negative_regulation of Localization of APC 2 0.13 2.3 0.13
197 INT250792 Positive_regulation of Localization of APC 1 0.15 0.48 0.13
198 INT89691 Regulation of Brca2 1 0.23 0.56 0.13
199 INT168244 Regulation of Transcription of Tp53 1 0.33 0.57 0.13
200 INT62489 Binding of Smc3 1 0.15 0.11 0.13
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